FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB4188, 357 aa 1>>>pF1KB4188 357 - 357 aa - 357 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.6934+/-0.000884; mu= 14.1067+/- 0.053 mean_var=64.1557+/-12.838, 0's: 0 Z-trim(105.0): 19 B-trim: 0 in 0/49 Lambda= 0.160124 statistics sampled from 8167 (8179) to 8167 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.632), E-opt: 0.2 (0.251), width: 16 Scan time: 2.580 The best scores are: opt bits E(32554) CCDS55818.1 TWF1 gene_id:5756|Hs108|chr12 ( 357) 2358 553.5 9.8e-158 CCDS31780.2 TWF1 gene_id:5756|Hs108|chr12 ( 350) 2282 536.0 1.9e-152 CCDS2849.1 TWF2 gene_id:11344|Hs108|chr3 ( 349) 1591 376.3 2.1e-104 >>CCDS55818.1 TWF1 gene_id:5756|Hs108|chr12 (357 aa) initn: 2358 init1: 2358 opt: 2358 Z-score: 2945.3 bits: 553.5 E(32554): 9.8e-158 Smith-Waterman score: 2358; 100.0% identity (100.0% similar) in 357 aa overlap (1-357:1-357) 10 20 30 40 50 60 pF1KB4 MSHQTGIQASEDVKEIFARARNGKYRLLKISIENEQLVIGSYSQPSDSWDKDYDSFVLPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 MSHQTGIQASEDVKEIFARARNGKYRLLKISIENEQLVIGSYSQPSDSWDKDYDSFVLPL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 LEDKQPCYILFRLDSQNAQGYEWIFIAWSPDHSHVRQKMLYAATRATLKKEFGGGHIKDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 LEDKQPCYILFRLDSQNAQGYEWIFIAWSPDHSHVRQKMLYAATRATLKKEFGGGHIKDE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 VFGTVKEDVSLHGYKKYLLSQSSPAPLTAAEEELRQIKINESPEDHIGVQTDVGVDTKHQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 VFGTVKEDVSLHGYKKYLLSQSSPAPLTAAEEELRQIKINESPEDHIGVQTDVGVDTKHQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 TLQGVAFPISREAFQALEKLNNRQLNYVQLEIDIKNEIIILANTTNTELKDLPKRIPKDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 TLQGVAFPISREAFQALEKLNNRQLNYVQLEIDIKNEIIILANTTNTELKDLPKRIPKDS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 ARYHFFLYKHSHEGDYLESIVFIYSMPGYTCSIRERMLYSSCKSRLLEIVERQLQMDVIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 ARYHFFLYKHSHEGDYLESIVFIYSMPGYTCSIRERMLYSSCKSRLLEIVERQLQMDVIR 250 260 270 280 290 300 310 320 330 340 350 pF1KB4 KIEIDNGDELTADFLYEEVHPKQHAHKQSFAKPKGPAGKRGIRRLIRGPAETEATTD ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 KIEIDNGDELTADFLYEEVHPKQHAHKQSFAKPKGPAGKRGIRRLIRGPAETEATTD 310 320 330 340 350 >>CCDS31780.2 TWF1 gene_id:5756|Hs108|chr12 (350 aa) initn: 1237 init1: 1237 opt: 2282 Z-score: 2850.6 bits: 536.0 E(32554): 1.9e-152 Smith-Waterman score: 2282; 98.0% identity (98.0% similar) in 357 aa overlap (1-357:1-350) 10 20 30 40 50 60 pF1KB4 MSHQTGIQASEDVKEIFARARNGKYRLLKISIENEQLVIGSYSQPSDSWDKDYDSFVLPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 MSHQTGIQASEDVKEIFARARNGKYRLLKISIENEQLVIGSYSQPSDSWDKDYDSFVLPL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 LEDKQPCYILFRLDSQNAQGYEWIFIAWSPDHSHVRQKMLYAATRATLKKEFGGGHIKDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 LEDKQPCYILFRLDSQNAQGYEWIFIAWSPDHSHVRQKMLYAATRATLKKEFGGGHIKDE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 VFGTVKEDVSLHGYKKYLLSQSSPAPLTAAEEELRQIKINESPEDHIGVQTDVGVDTKHQ ::::::::::::::::::::::::::::::::::::::::: :::::::::::: CCDS31 VFGTVKEDVSLHGYKKYLLSQSSPAPLTAAEEELRQIKINE-------VQTDVGVDTKHQ 130 140 150 160 170 190 200 210 220 230 240 pF1KB4 TLQGVAFPISREAFQALEKLNNRQLNYVQLEIDIKNEIIILANTTNTELKDLPKRIPKDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 TLQGVAFPISREAFQALEKLNNRQLNYVQLEIDIKNEIIILANTTNTELKDLPKRIPKDS 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB4 ARYHFFLYKHSHEGDYLESIVFIYSMPGYTCSIRERMLYSSCKSRLLEIVERQLQMDVIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 ARYHFFLYKHSHEGDYLESIVFIYSMPGYTCSIRERMLYSSCKSRLLEIVERQLQMDVIR 240 250 260 270 280 290 310 320 330 340 350 pF1KB4 KIEIDNGDELTADFLYEEVHPKQHAHKQSFAKPKGPAGKRGIRRLIRGPAETEATTD ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 KIEIDNGDELTADFLYEEVHPKQHAHKQSFAKPKGPAGKRGIRRLIRGPAETEATTD 300 310 320 330 340 350 >>CCDS2849.1 TWF2 gene_id:11344|Hs108|chr3 (349 aa) initn: 1574 init1: 812 opt: 1591 Z-score: 1987.9 bits: 376.3 E(32554): 2.1e-104 Smith-Waterman score: 1591; 64.1% identity (89.2% similar) in 351 aa overlap (1-351:1-344) 10 20 30 40 50 60 pF1KB4 MSHQTGIQASEDVKEIFARARNGKYRLLKISIENEQLVIGSYSQPSDSWDKDYDSFVLPL :.:::::.:.:..::.::.:: :. ::.:. ::.::::.:. ..: ::.::: :::: CCDS28 MAHQTGIHATEELKEFFAKARAGSVRLIKVVIEDEQLVLGASQEPVGRWDQDYDRAVLPL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 LEDKQPCYILFRLDSQNAQGYEWIFIAWSPDHSHVRQKMLYAATRATLKKEFGGGHIKDE :. .::::.:.:::::::::.::.:.:::::.: :: ::::::::::.:::::::::::: CCDS28 LDAQQPCYLLYRLDSQNAQGFEWLFLAWSPDNSPVRLKMLYAATRATVKKEFGGGHIKDE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 VFGTVKEDVSLHGYKKYLLSQSSPAPLTAAEEELRQIKINESPEDHIGVQTDVGVDTKHQ .:::::.:.:. ::.:.: : ..:::::.::.::.::.::: :.:...:..::: CCDS28 LFGTVKDDLSFAGYQKHLSSCAAPAPLTSAERELQQIRINE-------VKTEISVESKHQ 130 140 150 160 170 190 200 210 220 230 240 pF1KB4 TLQGVAFPISREAFQALEKLNNRQLNYVQLEIDIKNEIIILANTTNTELKDLPKRIPKDS ::::.:::.. :: .::..:.....::.:...:.. : : :..: :.. .::.:.:.:. CCDS28 TLQGLAFPLQPEAQRALQQLKQKMVNYIQMKLDLERETIELVHTEPTDVAQLPSRVPRDA 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB4 ARYHFFLYKHSHEGDYLESIVFIYSMPGYTCSIRERMLYSSCKSRLLEIVERQLQMDVIR ::::::::::.:::: :::.::::::::: :::.:::::::::::::. ::....... . CCDS28 ARYHFFLYKHTHEGDPLESVVFIYSMPGYKCSIKERMLYSSCKSRLLDSVEQDFHLEIAK 240 250 260 270 280 290 310 320 330 340 350 pF1KB4 KIEIDNGDELTADFLYEEVHPKQHAHKQSFAKPKGPAGKRGIRRLIRGPAETEATTD :::: .: ::::.:::.:::::::: ::.:::::::.:::: .::::::.: CCDS28 KIEIGDGAELTAEFLYDEVHPKQHAFKQAFAKPKGPGGKRGHKRLIRGPGENGDDS 300 310 320 330 340 357 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 14:35:48 2016 done: Thu Nov 3 14:35:48 2016 Total Scan time: 2.580 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]