FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB4221, 561 aa 1>>>pF1KB4221 561 - 561 aa - 561 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 12.4739+/-0.00102; mu= -12.4152+/- 0.062 mean_var=442.0189+/-91.087, 0's: 0 Z-trim(116.6): 34 B-trim: 176 in 1/53 Lambda= 0.061003 statistics sampled from 17234 (17265) to 17234 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.808), E-opt: 0.2 (0.53), width: 16 Scan time: 4.460 The best scores are: opt bits E(32554) CCDS33944.1 SH3BP2 gene_id:6452|Hs108|chr4 ( 561) 3943 361.2 1.9e-99 CCDS54715.1 SH3BP2 gene_id:6452|Hs108|chr4 ( 589) 3943 361.2 2e-99 CCDS54716.1 SH3BP2 gene_id:6452|Hs108|chr4 ( 618) 3943 361.2 2.1e-99 >>CCDS33944.1 SH3BP2 gene_id:6452|Hs108|chr4 (561 aa) initn: 3943 init1: 3943 opt: 3943 Z-score: 1898.7 bits: 361.2 E(32554): 1.9e-99 Smith-Waterman score: 3943; 100.0% identity (100.0% similar) in 561 aa overlap (1-561:1-561) 10 20 30 40 50 60 pF1KB4 MAAEEMHWPVPMKAIGAQNLLTMPGGVAKAGYLHKKGGTQLQLLKWPLRFVIIHKRCVYY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 MAAEEMHWPVPMKAIGAQNLLTMPGGVAKAGYLHKKGGTQLQLLKWPLRFVIIHKRCVYY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 FKSSTSASPQGAFSLSGYNRVMRAAEETTSNNVFPFKIIHISKKHRTWFFSASSEEERKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 FKSSTSASPQGAFSLSGYNRVMRAAEETTSNNVFPFKIIHISKKHRTWFFSASSEEERKS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 WMALLRREIGHFHEKKDLPLDTSDSSSDTDSFYGAVERPVDISLSPYPTDNEDYEHDDED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 WMALLRREIGHFHEKKDLPLDTSDSSSDTDSFYGAVERPVDISLSPYPTDNEDYEHDDED 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 DSYLEPDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 DSYLEPDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 KHGLPDVGLAAEDSKRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGLRKPPCFRES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 KHGLPDVGLAAEDSKRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGLRKPPCFRES 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 ASPSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEPPPVPANKPKFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 ASPSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEPPPVPANKPKFL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB4 KIAEEDPPREAAMPGLFVPPVAPRPPALKLPVPEAMARPAVLPRPEKPQLPHLQRSPPDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 KIAEEDPPREAAMPGLFVPPVAPRPPALKLPVPEAMARPAVLPRPEKPQLPHLQRSPPDG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB4 QSFRSFSFEKPRQPSQADTGGDDSDEDYEKVPLPNSVFVNTTESCEVERLFKATSPRGEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 QSFRSFSFEKPRQPSQADTGGDDSDEDYEKVPLPNSVFVNTTESCEVERLFKATSPRGEP 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB4 QDGLYCIRNSSTKSGKVLVVWDETSNKVRNYRIFEKDSKFYLEGEVLFVSVGSMVEHYHT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 QDGLYCIRNSSTKSGKVLVVWDETSNKVRNYRIFEKDSKFYLEGEVLFVSVGSMVEHYHT 490 500 510 520 530 540 550 560 pF1KB4 HVLPSHQSLLLRHPYGYTGPR ::::::::::::::::::::: CCDS33 HVLPSHQSLLLRHPYGYTGPR 550 560 >>CCDS54715.1 SH3BP2 gene_id:6452|Hs108|chr4 (589 aa) initn: 3943 init1: 3943 opt: 3943 Z-score: 1898.5 bits: 361.2 E(32554): 2e-99 Smith-Waterman score: 3943; 100.0% identity (100.0% similar) in 561 aa overlap (1-561:29-589) 10 20 30 pF1KB4 MAAEEMHWPVPMKAIGAQNLLTMPGGVAKAGY :::::::::::::::::::::::::::::::: CCDS54 MASLGPRTPAPSRSRGRRAMCWVSTISFMAAEEMHWPVPMKAIGAQNLLTMPGGVAKAGY 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB4 LHKKGGTQLQLLKWPLRFVIIHKRCVYYFKSSTSASPQGAFSLSGYNRVMRAAEETTSNN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 LHKKGGTQLQLLKWPLRFVIIHKRCVYYFKSSTSASPQGAFSLSGYNRVMRAAEETTSNN 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB4 VFPFKIIHISKKHRTWFFSASSEEERKSWMALLRREIGHFHEKKDLPLDTSDSSSDTDSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 VFPFKIIHISKKHRTWFFSASSEEERKSWMALLRREIGHFHEKKDLPLDTSDSSSDTDSF 130 140 150 160 170 180 160 170 180 190 200 210 pF1KB4 YGAVERPVDISLSPYPTDNEDYEHDDEDDSYLEPDSPEPGRLEDALMHPPAYPPPPVPTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 YGAVERPVDISLSPYPTDNEDYEHDDEDDSYLEPDSPEPGRLEDALMHPPAYPPPPVPTP 190 200 210 220 230 240 220 230 240 250 260 270 pF1KB4 RKPAFSDMPRAHSFTSKGPGPLLPPPPPKHGLPDVGLAAEDSKRDPLCPRRAEPCPRVPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 RKPAFSDMPRAHSFTSKGPGPLLPPPPPKHGLPDVGLAAEDSKRDPLCPRRAEPCPRVPA 250 260 270 280 290 300 280 290 300 310 320 330 pF1KB4 TPRRMSDPPLSTMPTAPGLRKPPCFRESASPSPEPWTPGHGACSTSSAAIMATATSRNCD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 TPRRMSDPPLSTMPTAPGLRKPPCFRESASPSPEPWTPGHGACSTSSAAIMATATSRNCD 310 320 330 340 350 360 340 350 360 370 380 390 pF1KB4 KLKSFHLSPRGPPTSEPPPVPANKPKFLKIAEEDPPREAAMPGLFVPPVAPRPPALKLPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 KLKSFHLSPRGPPTSEPPPVPANKPKFLKIAEEDPPREAAMPGLFVPPVAPRPPALKLPV 370 380 390 400 410 420 400 410 420 430 440 450 pF1KB4 PEAMARPAVLPRPEKPQLPHLQRSPPDGQSFRSFSFEKPRQPSQADTGGDDSDEDYEKVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 PEAMARPAVLPRPEKPQLPHLQRSPPDGQSFRSFSFEKPRQPSQADTGGDDSDEDYEKVP 430 440 450 460 470 480 460 470 480 490 500 510 pF1KB4 LPNSVFVNTTESCEVERLFKATSPRGEPQDGLYCIRNSSTKSGKVLVVWDETSNKVRNYR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 LPNSVFVNTTESCEVERLFKATSPRGEPQDGLYCIRNSSTKSGKVLVVWDETSNKVRNYR 490 500 510 520 530 540 520 530 540 550 560 pF1KB4 IFEKDSKFYLEGEVLFVSVGSMVEHYHTHVLPSHQSLLLRHPYGYTGPR ::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 IFEKDSKFYLEGEVLFVSVGSMVEHYHTHVLPSHQSLLLRHPYGYTGPR 550 560 570 580 >>CCDS54716.1 SH3BP2 gene_id:6452|Hs108|chr4 (618 aa) initn: 3943 init1: 3943 opt: 3943 Z-score: 1898.2 bits: 361.2 E(32554): 2.1e-99 Smith-Waterman score: 3943; 100.0% identity (100.0% similar) in 561 aa overlap (1-561:58-618) 10 20 30 pF1KB4 MAAEEMHWPVPMKAIGAQNLLTMPGGVAKA :::::::::::::::::::::::::::::: CCDS54 RGPGPCRCSQGRRAWIAPGKPAMPAAWTPFMAAEEMHWPVPMKAIGAQNLLTMPGGVAKA 30 40 50 60 70 80 40 50 60 70 80 90 pF1KB4 GYLHKKGGTQLQLLKWPLRFVIIHKRCVYYFKSSTSASPQGAFSLSGYNRVMRAAEETTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 GYLHKKGGTQLQLLKWPLRFVIIHKRCVYYFKSSTSASPQGAFSLSGYNRVMRAAEETTS 90 100 110 120 130 140 100 110 120 130 140 150 pF1KB4 NNVFPFKIIHISKKHRTWFFSASSEEERKSWMALLRREIGHFHEKKDLPLDTSDSSSDTD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 NNVFPFKIIHISKKHRTWFFSASSEEERKSWMALLRREIGHFHEKKDLPLDTSDSSSDTD 150 160 170 180 190 200 160 170 180 190 200 210 pF1KB4 SFYGAVERPVDISLSPYPTDNEDYEHDDEDDSYLEPDSPEPGRLEDALMHPPAYPPPPVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 SFYGAVERPVDISLSPYPTDNEDYEHDDEDDSYLEPDSPEPGRLEDALMHPPAYPPPPVP 210 220 230 240 250 260 220 230 240 250 260 270 pF1KB4 TPRKPAFSDMPRAHSFTSKGPGPLLPPPPPKHGLPDVGLAAEDSKRDPLCPRRAEPCPRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 TPRKPAFSDMPRAHSFTSKGPGPLLPPPPPKHGLPDVGLAAEDSKRDPLCPRRAEPCPRV 270 280 290 300 310 320 280 290 300 310 320 330 pF1KB4 PATPRRMSDPPLSTMPTAPGLRKPPCFRESASPSPEPWTPGHGACSTSSAAIMATATSRN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 PATPRRMSDPPLSTMPTAPGLRKPPCFRESASPSPEPWTPGHGACSTSSAAIMATATSRN 330 340 350 360 370 380 340 350 360 370 380 390 pF1KB4 CDKLKSFHLSPRGPPTSEPPPVPANKPKFLKIAEEDPPREAAMPGLFVPPVAPRPPALKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 CDKLKSFHLSPRGPPTSEPPPVPANKPKFLKIAEEDPPREAAMPGLFVPPVAPRPPALKL 390 400 410 420 430 440 400 410 420 430 440 450 pF1KB4 PVPEAMARPAVLPRPEKPQLPHLQRSPPDGQSFRSFSFEKPRQPSQADTGGDDSDEDYEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 PVPEAMARPAVLPRPEKPQLPHLQRSPPDGQSFRSFSFEKPRQPSQADTGGDDSDEDYEK 450 460 470 480 490 500 460 470 480 490 500 510 pF1KB4 VPLPNSVFVNTTESCEVERLFKATSPRGEPQDGLYCIRNSSTKSGKVLVVWDETSNKVRN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 VPLPNSVFVNTTESCEVERLFKATSPRGEPQDGLYCIRNSSTKSGKVLVVWDETSNKVRN 510 520 530 540 550 560 520 530 540 550 560 pF1KB4 YRIFEKDSKFYLEGEVLFVSVGSMVEHYHTHVLPSHQSLLLRHPYGYTGPR ::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 YRIFEKDSKFYLEGEVLFVSVGSMVEHYHTHVLPSHQSLLLRHPYGYTGPR 570 580 590 600 610 561 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 14:37:50 2016 done: Thu Nov 3 14:37:51 2016 Total Scan time: 4.460 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]