Result of FASTA (omim) for
pF1KB4221
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB4221, 561 aa
1>>>pF1KB4221 561 - 561 aa - 561 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 13.7017+/-0.000432; mu= -19.5708+/- 0.027
mean_var=547.0957+/-110.697, 0's: 0 Z-trim(124.5): 20 B-trim: 0 in 0/61
Lambda= 0.054833
statistics sampled from 46319 (46379) to 46319 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.814), E-opt: 0.2 (0.544), width: 16
Scan time: 13.680
The best scores are: opt bits E(85289)
NP_001116153 (OMIM: 118400,602104) SH3 domain-bind ( 561) 3943 326.6 1.3e-88
NP_003014 (OMIM: 118400,602104) SH3 domain-binding ( 561) 3943 326.6 1.3e-88
NP_001139327 (OMIM: 118400,602104) SH3 domain-bind ( 589) 3943 326.6 1.4e-88
NP_001139328 (OMIM: 118400,602104) SH3 domain-bind ( 618) 3943 326.6 1.4e-88
>>NP_001116153 (OMIM: 118400,602104) SH3 domain-binding (561 aa)
initn: 3943 init1: 3943 opt: 3943 Z-score: 1711.8 bits: 326.6 E(85289): 1.3e-88
Smith-Waterman score: 3943; 100.0% identity (100.0% similar) in 561 aa overlap (1-561:1-561)
10 20 30 40 50 60
pF1KB4 MAAEEMHWPVPMKAIGAQNLLTMPGGVAKAGYLHKKGGTQLQLLKWPLRFVIIHKRCVYY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAAEEMHWPVPMKAIGAQNLLTMPGGVAKAGYLHKKGGTQLQLLKWPLRFVIIHKRCVYY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 FKSSTSASPQGAFSLSGYNRVMRAAEETTSNNVFPFKIIHISKKHRTWFFSASSEEERKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FKSSTSASPQGAFSLSGYNRVMRAAEETTSNNVFPFKIIHISKKHRTWFFSASSEEERKS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 WMALLRREIGHFHEKKDLPLDTSDSSSDTDSFYGAVERPVDISLSPYPTDNEDYEHDDED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WMALLRREIGHFHEKKDLPLDTSDSSSDTDSFYGAVERPVDISLSPYPTDNEDYEHDDED
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 DSYLEPDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DSYLEPDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 KHGLPDVGLAAEDSKRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGLRKPPCFRES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KHGLPDVGLAAEDSKRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGLRKPPCFRES
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 ASPSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEPPPVPANKPKFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ASPSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEPPPVPANKPKFL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 KIAEEDPPREAAMPGLFVPPVAPRPPALKLPVPEAMARPAVLPRPEKPQLPHLQRSPPDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KIAEEDPPREAAMPGLFVPPVAPRPPALKLPVPEAMARPAVLPRPEKPQLPHLQRSPPDG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 QSFRSFSFEKPRQPSQADTGGDDSDEDYEKVPLPNSVFVNTTESCEVERLFKATSPRGEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QSFRSFSFEKPRQPSQADTGGDDSDEDYEKVPLPNSVFVNTTESCEVERLFKATSPRGEP
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB4 QDGLYCIRNSSTKSGKVLVVWDETSNKVRNYRIFEKDSKFYLEGEVLFVSVGSMVEHYHT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QDGLYCIRNSSTKSGKVLVVWDETSNKVRNYRIFEKDSKFYLEGEVLFVSVGSMVEHYHT
490 500 510 520 530 540
550 560
pF1KB4 HVLPSHQSLLLRHPYGYTGPR
:::::::::::::::::::::
NP_001 HVLPSHQSLLLRHPYGYTGPR
550 560
>>NP_003014 (OMIM: 118400,602104) SH3 domain-binding pro (561 aa)
initn: 3943 init1: 3943 opt: 3943 Z-score: 1711.8 bits: 326.6 E(85289): 1.3e-88
Smith-Waterman score: 3943; 100.0% identity (100.0% similar) in 561 aa overlap (1-561:1-561)
10 20 30 40 50 60
pF1KB4 MAAEEMHWPVPMKAIGAQNLLTMPGGVAKAGYLHKKGGTQLQLLKWPLRFVIIHKRCVYY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MAAEEMHWPVPMKAIGAQNLLTMPGGVAKAGYLHKKGGTQLQLLKWPLRFVIIHKRCVYY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 FKSSTSASPQGAFSLSGYNRVMRAAEETTSNNVFPFKIIHISKKHRTWFFSASSEEERKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 FKSSTSASPQGAFSLSGYNRVMRAAEETTSNNVFPFKIIHISKKHRTWFFSASSEEERKS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 WMALLRREIGHFHEKKDLPLDTSDSSSDTDSFYGAVERPVDISLSPYPTDNEDYEHDDED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 WMALLRREIGHFHEKKDLPLDTSDSSSDTDSFYGAVERPVDISLSPYPTDNEDYEHDDED
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 DSYLEPDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 DSYLEPDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 KHGLPDVGLAAEDSKRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGLRKPPCFRES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 KHGLPDVGLAAEDSKRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGLRKPPCFRES
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 ASPSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEPPPVPANKPKFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 ASPSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEPPPVPANKPKFL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 KIAEEDPPREAAMPGLFVPPVAPRPPALKLPVPEAMARPAVLPRPEKPQLPHLQRSPPDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 KIAEEDPPREAAMPGLFVPPVAPRPPALKLPVPEAMARPAVLPRPEKPQLPHLQRSPPDG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 QSFRSFSFEKPRQPSQADTGGDDSDEDYEKVPLPNSVFVNTTESCEVERLFKATSPRGEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 QSFRSFSFEKPRQPSQADTGGDDSDEDYEKVPLPNSVFVNTTESCEVERLFKATSPRGEP
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB4 QDGLYCIRNSSTKSGKVLVVWDETSNKVRNYRIFEKDSKFYLEGEVLFVSVGSMVEHYHT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 QDGLYCIRNSSTKSGKVLVVWDETSNKVRNYRIFEKDSKFYLEGEVLFVSVGSMVEHYHT
490 500 510 520 530 540
550 560
pF1KB4 HVLPSHQSLLLRHPYGYTGPR
:::::::::::::::::::::
NP_003 HVLPSHQSLLLRHPYGYTGPR
550 560
>>NP_001139327 (OMIM: 118400,602104) SH3 domain-binding (589 aa)
initn: 3943 init1: 3943 opt: 3943 Z-score: 1711.5 bits: 326.6 E(85289): 1.4e-88
Smith-Waterman score: 3943; 100.0% identity (100.0% similar) in 561 aa overlap (1-561:29-589)
10 20 30
pF1KB4 MAAEEMHWPVPMKAIGAQNLLTMPGGVAKAGY
::::::::::::::::::::::::::::::::
NP_001 MASLGPRTPAPSRSRGRRAMCWVSTISFMAAEEMHWPVPMKAIGAQNLLTMPGGVAKAGY
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB4 LHKKGGTQLQLLKWPLRFVIIHKRCVYYFKSSTSASPQGAFSLSGYNRVMRAAEETTSNN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LHKKGGTQLQLLKWPLRFVIIHKRCVYYFKSSTSASPQGAFSLSGYNRVMRAAEETTSNN
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB4 VFPFKIIHISKKHRTWFFSASSEEERKSWMALLRREIGHFHEKKDLPLDTSDSSSDTDSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VFPFKIIHISKKHRTWFFSASSEEERKSWMALLRREIGHFHEKKDLPLDTSDSSSDTDSF
130 140 150 160 170 180
160 170 180 190 200 210
pF1KB4 YGAVERPVDISLSPYPTDNEDYEHDDEDDSYLEPDSPEPGRLEDALMHPPAYPPPPVPTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YGAVERPVDISLSPYPTDNEDYEHDDEDDSYLEPDSPEPGRLEDALMHPPAYPPPPVPTP
190 200 210 220 230 240
220 230 240 250 260 270
pF1KB4 RKPAFSDMPRAHSFTSKGPGPLLPPPPPKHGLPDVGLAAEDSKRDPLCPRRAEPCPRVPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RKPAFSDMPRAHSFTSKGPGPLLPPPPPKHGLPDVGLAAEDSKRDPLCPRRAEPCPRVPA
250 260 270 280 290 300
280 290 300 310 320 330
pF1KB4 TPRRMSDPPLSTMPTAPGLRKPPCFRESASPSPEPWTPGHGACSTSSAAIMATATSRNCD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TPRRMSDPPLSTMPTAPGLRKPPCFRESASPSPEPWTPGHGACSTSSAAIMATATSRNCD
310 320 330 340 350 360
340 350 360 370 380 390
pF1KB4 KLKSFHLSPRGPPTSEPPPVPANKPKFLKIAEEDPPREAAMPGLFVPPVAPRPPALKLPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KLKSFHLSPRGPPTSEPPPVPANKPKFLKIAEEDPPREAAMPGLFVPPVAPRPPALKLPV
370 380 390 400 410 420
400 410 420 430 440 450
pF1KB4 PEAMARPAVLPRPEKPQLPHLQRSPPDGQSFRSFSFEKPRQPSQADTGGDDSDEDYEKVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PEAMARPAVLPRPEKPQLPHLQRSPPDGQSFRSFSFEKPRQPSQADTGGDDSDEDYEKVP
430 440 450 460 470 480
460 470 480 490 500 510
pF1KB4 LPNSVFVNTTESCEVERLFKATSPRGEPQDGLYCIRNSSTKSGKVLVVWDETSNKVRNYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LPNSVFVNTTESCEVERLFKATSPRGEPQDGLYCIRNSSTKSGKVLVVWDETSNKVRNYR
490 500 510 520 530 540
520 530 540 550 560
pF1KB4 IFEKDSKFYLEGEVLFVSVGSMVEHYHTHVLPSHQSLLLRHPYGYTGPR
:::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IFEKDSKFYLEGEVLFVSVGSMVEHYHTHVLPSHQSLLLRHPYGYTGPR
550 560 570 580
>>NP_001139328 (OMIM: 118400,602104) SH3 domain-binding (618 aa)
initn: 3943 init1: 3943 opt: 3943 Z-score: 1711.2 bits: 326.6 E(85289): 1.4e-88
Smith-Waterman score: 3943; 100.0% identity (100.0% similar) in 561 aa overlap (1-561:58-618)
10 20 30
pF1KB4 MAAEEMHWPVPMKAIGAQNLLTMPGGVAKA
::::::::::::::::::::::::::::::
NP_001 RGPGPCRCSQGRRAWIAPGKPAMPAAWTPFMAAEEMHWPVPMKAIGAQNLLTMPGGVAKA
30 40 50 60 70 80
40 50 60 70 80 90
pF1KB4 GYLHKKGGTQLQLLKWPLRFVIIHKRCVYYFKSSTSASPQGAFSLSGYNRVMRAAEETTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GYLHKKGGTQLQLLKWPLRFVIIHKRCVYYFKSSTSASPQGAFSLSGYNRVMRAAEETTS
90 100 110 120 130 140
100 110 120 130 140 150
pF1KB4 NNVFPFKIIHISKKHRTWFFSASSEEERKSWMALLRREIGHFHEKKDLPLDTSDSSSDTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NNVFPFKIIHISKKHRTWFFSASSEEERKSWMALLRREIGHFHEKKDLPLDTSDSSSDTD
150 160 170 180 190 200
160 170 180 190 200 210
pF1KB4 SFYGAVERPVDISLSPYPTDNEDYEHDDEDDSYLEPDSPEPGRLEDALMHPPAYPPPPVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SFYGAVERPVDISLSPYPTDNEDYEHDDEDDSYLEPDSPEPGRLEDALMHPPAYPPPPVP
210 220 230 240 250 260
220 230 240 250 260 270
pF1KB4 TPRKPAFSDMPRAHSFTSKGPGPLLPPPPPKHGLPDVGLAAEDSKRDPLCPRRAEPCPRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TPRKPAFSDMPRAHSFTSKGPGPLLPPPPPKHGLPDVGLAAEDSKRDPLCPRRAEPCPRV
270 280 290 300 310 320
280 290 300 310 320 330
pF1KB4 PATPRRMSDPPLSTMPTAPGLRKPPCFRESASPSPEPWTPGHGACSTSSAAIMATATSRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PATPRRMSDPPLSTMPTAPGLRKPPCFRESASPSPEPWTPGHGACSTSSAAIMATATSRN
330 340 350 360 370 380
340 350 360 370 380 390
pF1KB4 CDKLKSFHLSPRGPPTSEPPPVPANKPKFLKIAEEDPPREAAMPGLFVPPVAPRPPALKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CDKLKSFHLSPRGPPTSEPPPVPANKPKFLKIAEEDPPREAAMPGLFVPPVAPRPPALKL
390 400 410 420 430 440
400 410 420 430 440 450
pF1KB4 PVPEAMARPAVLPRPEKPQLPHLQRSPPDGQSFRSFSFEKPRQPSQADTGGDDSDEDYEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVPEAMARPAVLPRPEKPQLPHLQRSPPDGQSFRSFSFEKPRQPSQADTGGDDSDEDYEK
450 460 470 480 490 500
460 470 480 490 500 510
pF1KB4 VPLPNSVFVNTTESCEVERLFKATSPRGEPQDGLYCIRNSSTKSGKVLVVWDETSNKVRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPLPNSVFVNTTESCEVERLFKATSPRGEPQDGLYCIRNSSTKSGKVLVVWDETSNKVRN
510 520 530 540 550 560
520 530 540 550 560
pF1KB4 YRIFEKDSKFYLEGEVLFVSVGSMVEHYHTHVLPSHQSLLLRHPYGYTGPR
:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YRIFEKDSKFYLEGEVLFVSVGSMVEHYHTHVLPSHQSLLLRHPYGYTGPR
570 580 590 600 610
561 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 14:37:51 2016 done: Thu Nov 3 14:37:53 2016
Total Scan time: 13.680 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]