FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB4223, 416 aa 1>>>pF1KB4223 416 - 416 aa - 416 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.2749+/-0.000381; mu= 12.6048+/- 0.024 mean_var=83.6264+/-16.694, 0's: 0 Z-trim(113.6): 94 B-trim: 66 in 1/54 Lambda= 0.140250 statistics sampled from 22960 (23081) to 22960 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.643), E-opt: 0.2 (0.271), width: 16 Scan time: 7.600 The best scores are: opt bits E(85289) NP_003550 (OMIM: 603261) phosphatidylinositol 5-ph ( 416) 2757 567.8 1.8e-161 XP_016880685 (OMIM: 603261) PREDICTED: phosphatidy ( 352) 2347 484.8 1.5e-136 NP_005019 (OMIM: 603140) phosphatidylinositol 5-ph ( 406) 2115 437.9 2.2e-122 NP_001316991 (OMIM: 603140) phosphatidylinositol 5 ( 347) 1849 384.0 3.1e-106 XP_016871820 (OMIM: 603140) PREDICTED: phosphatidy ( 347) 1849 384.0 3.1e-106 XP_016871819 (OMIM: 603140) PREDICTED: phosphatidy ( 347) 1849 384.0 3.1e-106 NP_079055 (OMIM: 617104) phosphatidylinositol 5-ph ( 421) 1782 370.5 4.5e-102 NP_001139730 (OMIM: 617104) phosphatidylinositol 5 ( 421) 1782 370.5 4.5e-102 XP_016880687 (OMIM: 603261) PREDICTED: phosphatidy ( 257) 1705 354.8 1.4e-97 XP_011523632 (OMIM: 603261) PREDICTED: phosphatidy ( 284) 1640 341.7 1.4e-93 XP_011523629 (OMIM: 603261) PREDICTED: phosphatidy ( 379) 1640 341.7 1.8e-93 XP_011523628 (OMIM: 603261) PREDICTED: phosphatidy ( 443) 1640 341.8 2.1e-93 XP_016880686 (OMIM: 603261) PREDICTED: phosphatidy ( 278) 1636 340.9 2.4e-93 XP_016880688 (OMIM: 603261) PREDICTED: phosphatidy ( 248) 1634 340.4 2.9e-93 NP_001139731 (OMIM: 617104) phosphatidylinositol 5 ( 403) 1398 292.8 1.1e-78 XP_016871821 (OMIM: 603140) PREDICTED: phosphatidy ( 296) 1229 258.5 1.6e-68 XP_006717513 (OMIM: 603140) PREDICTED: phosphatidy ( 355) 1229 258.6 1.8e-68 XP_011523631 (OMIM: 603261) PREDICTED: phosphatidy ( 317) 1123 237.1 4.8e-62 XP_016875462 (OMIM: 617104) PREDICTED: phosphatidy ( 251) 1072 226.7 5e-59 NP_001139732 (OMIM: 617104) phosphatidylinositol 5 ( 373) 1072 226.8 7.1e-59 XP_011537049 (OMIM: 617104) PREDICTED: phosphatidy ( 249) 1046 221.5 1.9e-57 XP_005269209 (OMIM: 617104) PREDICTED: phosphatidy ( 408) 985 209.2 1.5e-53 XP_006717364 (OMIM: 602745) PREDICTED: phosphatidy ( 502) 617 134.8 4.7e-31 XP_016870680 (OMIM: 602745) PREDICTED: phosphatidy ( 502) 617 134.8 4.7e-31 NP_001265182 (OMIM: 602745) phosphatidylinositol 4 ( 502) 617 134.8 4.7e-31 NP_003549 (OMIM: 602745) phosphatidylinositol 4-ph ( 540) 617 134.8 5.1e-31 XP_005252318 (OMIM: 602745) PREDICTED: phosphatidy ( 540) 617 134.8 5.1e-31 XP_016870679 (OMIM: 602745) PREDICTED: phosphatidy ( 540) 617 134.8 5.1e-31 XP_011517386 (OMIM: 602745) PREDICTED: phosphatidy ( 540) 617 134.8 5.1e-31 XP_016870677 (OMIM: 602745) PREDICTED: phosphatidy ( 540) 617 134.8 5.1e-31 XP_011517384 (OMIM: 602745) PREDICTED: phosphatidy ( 540) 617 134.8 5.1e-31 XP_006717363 (OMIM: 602745) PREDICTED: phosphatidy ( 540) 617 134.8 5.1e-31 XP_005252319 (OMIM: 602745) PREDICTED: phosphatidy ( 540) 617 134.8 5.1e-31 XP_011517385 (OMIM: 602745) PREDICTED: phosphatidy ( 540) 617 134.8 5.1e-31 XP_016870678 (OMIM: 602745) PREDICTED: phosphatidy ( 540) 617 134.8 5.1e-31 XP_016857929 (OMIM: 603275) PREDICTED: phosphatidy ( 484) 537 118.6 3.4e-26 XP_016857928 (OMIM: 603275) PREDICTED: phosphatidy ( 485) 537 118.6 3.4e-26 NP_001129109 (OMIM: 603275) phosphatidylinositol 4 ( 500) 537 118.6 3.5e-26 XP_011508351 (OMIM: 603275) PREDICTED: phosphatidy ( 526) 537 118.6 3.7e-26 XP_011508350 (OMIM: 603275) PREDICTED: phosphatidy ( 526) 537 118.6 3.7e-26 XP_016857930 (OMIM: 603275) PREDICTED: phosphatidy ( 526) 537 118.6 3.7e-26 XP_006711630 (OMIM: 603275) PREDICTED: phosphatidy ( 526) 537 118.6 3.7e-26 XP_011508348 (OMIM: 603275) PREDICTED: phosphatidy ( 541) 537 118.6 3.8e-26 XP_005245589 (OMIM: 603275) PREDICTED: phosphatidy ( 542) 537 118.6 3.8e-26 NP_003548 (OMIM: 603275) phosphatidylinositol 4-ph ( 549) 537 118.6 3.8e-26 NP_001317618 (OMIM: 603275) phosphatidylinositol 4 ( 550) 537 118.6 3.8e-26 XP_011508347 (OMIM: 603275) PREDICTED: phosphatidy ( 553) 537 118.6 3.9e-26 XP_005245587 (OMIM: 603275) PREDICTED: phosphatidy ( 554) 537 118.6 3.9e-26 XP_011508345 (OMIM: 603275) PREDICTED: phosphatidy ( 555) 537 118.6 3.9e-26 XP_005245585 (OMIM: 603275) PREDICTED: phosphatidy ( 560) 537 118.6 3.9e-26 >>NP_003550 (OMIM: 603261) phosphatidylinositol 5-phosph (416 aa) initn: 2757 init1: 2757 opt: 2757 Z-score: 3019.9 bits: 567.8 E(85289): 1.8e-161 Smith-Waterman score: 2757; 100.0% identity (100.0% similar) in 416 aa overlap (1-416:1-416) 10 20 30 40 50 60 pF1KB4 MSSNCTSTTAVAVAPLSASKTKTKKKHFVCQKVKLFRASEPILSVLMWGVNHTINELSNV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 MSSNCTSTTAVAVAPLSASKTKTKKKHFVCQKVKLFRASEPILSVLMWGVNHTINELSNV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 PVPVMLMPDDFKAYSKIKVDNHLFNKENLPSRFKFKEYCPMVFRNLRERFGIDDQDYQNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 PVPVMLMPDDFKAYSKIKVDNHLFNKENLPSRFKFKEYCPMVFRNLRERFGIDDQDYQNS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 VTRSAPINSDSQGRCGTRFLTTYDRRFVIKTVSSEDVAEMHNILKKYHQFIVECHGNTLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 VTRSAPINSDSQGRCGTRFLTTYDRRFVIKTVSSEDVAEMHNILKKYHQFIVECHGNTLL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 PQFLGMYRLTVDGVETYMVVTRNVFSHRLTVHRKYDLKGSTVAREASDKEKAKDLPTFKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 PQFLGMYRLTVDGVETYMVVTRNVFSHRLTVHRKYDLKGSTVAREASDKEKAKDLPTFKD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 NDFLNEGQKLHVGEESKKNFLEKLKRDVEFLAQLKIMDYSLLVGIHDVDRAEQEEMEVEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 NDFLNEGQKLHVGEESKKNFLEKLKRDVEFLAQLKIMDYSLLVGIHDVDRAEQEEMEVEE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 RAEDEECENDGVGGNLLCSYGTPPDSPGNLLSFPRFFGPGEFDPSVDVYAMKSHESSPKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 RAEDEECENDGVGGNLLCSYGTPPDSPGNLLSFPRFFGPGEFDPSVDVYAMKSHESSPKK 310 320 330 340 350 360 370 380 390 400 410 pF1KB4 EVYFMAIIDILTPYDTKKKAAHAAKTVKHGAGAEISTVNPEQYSKRFNEFMSNILT :::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 EVYFMAIIDILTPYDTKKKAAHAAKTVKHGAGAEISTVNPEQYSKRFNEFMSNILT 370 380 390 400 410 >>XP_016880685 (OMIM: 603261) PREDICTED: phosphatidylino (352 aa) initn: 2347 init1: 2347 opt: 2347 Z-score: 2572.7 bits: 484.8 E(85289): 1.5e-136 Smith-Waterman score: 2347; 100.0% identity (100.0% similar) in 352 aa overlap (65-416:1-352) 40 50 60 70 80 90 pF1KB4 LFRASEPILSVLMWGVNHTINELSNVPVPVMLMPDDFKAYSKIKVDNHLFNKENLPSRFK :::::::::::::::::::::::::::::: XP_016 MLMPDDFKAYSKIKVDNHLFNKENLPSRFK 10 20 30 100 110 120 130 140 150 pF1KB4 FKEYCPMVFRNLRERFGIDDQDYQNSVTRSAPINSDSQGRCGTRFLTTYDRRFVIKTVSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FKEYCPMVFRNLRERFGIDDQDYQNSVTRSAPINSDSQGRCGTRFLTTYDRRFVIKTVSS 40 50 60 70 80 90 160 170 180 190 200 210 pF1KB4 EDVAEMHNILKKYHQFIVECHGNTLLPQFLGMYRLTVDGVETYMVVTRNVFSHRLTVHRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EDVAEMHNILKKYHQFIVECHGNTLLPQFLGMYRLTVDGVETYMVVTRNVFSHRLTVHRK 100 110 120 130 140 150 220 230 240 250 260 270 pF1KB4 YDLKGSTVAREASDKEKAKDLPTFKDNDFLNEGQKLHVGEESKKNFLEKLKRDVEFLAQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YDLKGSTVAREASDKEKAKDLPTFKDNDFLNEGQKLHVGEESKKNFLEKLKRDVEFLAQL 160 170 180 190 200 210 280 290 300 310 320 330 pF1KB4 KIMDYSLLVGIHDVDRAEQEEMEVEERAEDEECENDGVGGNLLCSYGTPPDSPGNLLSFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KIMDYSLLVGIHDVDRAEQEEMEVEERAEDEECENDGVGGNLLCSYGTPPDSPGNLLSFP 220 230 240 250 260 270 340 350 360 370 380 390 pF1KB4 RFFGPGEFDPSVDVYAMKSHESSPKKEVYFMAIIDILTPYDTKKKAAHAAKTVKHGAGAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RFFGPGEFDPSVDVYAMKSHESSPKKEVYFMAIIDILTPYDTKKKAAHAAKTVKHGAGAE 280 290 300 310 320 330 400 410 pF1KB4 ISTVNPEQYSKRFNEFMSNILT :::::::::::::::::::::: XP_016 ISTVNPEQYSKRFNEFMSNILT 340 350 >>NP_005019 (OMIM: 603140) phosphatidylinositol 5-phosph (406 aa) initn: 2125 init1: 1643 opt: 2115 Z-score: 2318.0 bits: 437.9 E(85289): 2.2e-122 Smith-Waterman score: 2115; 78.7% identity (92.5% similar) in 399 aa overlap (18-416:13-406) 10 20 30 40 50 60 pF1KB4 MSSNCTSTTAVAVAPLSASKTKTKKKHFVCQKVKLFRASEPILSVLMWGVNHTINELSNV :::::::::::: :::::::::.:.::::::::::.:::::.: NP_005 MATPGNLGSSVLASKTKTKKKHFVAQKVKLFRASDPLLSVLMWGVNHSINELSHV 10 20 30 40 50 70 80 90 100 110 120 pF1KB4 PVPVMLMPDDFKAYSKIKVDNHLFNKENLPSRFKFKEYCPMVFRNLRERFGIDDQDYQNS .::::::::::::::::::::::::::.::.::::::::::::::::::::::::.::: NP_005 QIPVMLMPDDFKAYSKIKVDNHLFNKENMPSHFKFKEYCPMVFRNLRERFGIDDQDFQNS 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB4 VTRSAPINSDSQGRCGTRFLTTYDRRFVIKTVSSEDVAEMHNILKKYHQFIVECHGNTLL .:::::. .:::.: :.:: :.::.:..:::..::::::::::::::::.:::::: ::: NP_005 LTRSAPLPNDSQARSGARFHTSYDKRYIIKTITSEDVAEMHNILKKYHQYIVECHGITLL 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB4 PQFLGMYRLTVDGVETYMVVTRNVFSHRLTVHRKYDLKGSTVAREASDKEKAKDLPTFKD :::::::::.::::: :..::::::::::.:.:::::::::::::::::::::.:::.:: NP_005 PQFLGMYRLNVDGVEIYVIVTRNVFSHRLSVYRKYDLKGSTVAREASDKEKAKELPTLKD 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB4 NDFLNEGQKLHVGEESKKNFLEKLKRDVEFLAQLKIMDYSLLVGIHDVDRAEQEEMEVEE :::.:::::... ...:: ::::::.:::::::::.::::::::::::.::::::.: :: NP_005 NDFINEGQKIYIDDNNKKVFLEKLKKDVEFLAQLKLMDYSLLVGIHDVERAEQEEVECEE 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB4 RAEDEECENDGVGGNLLCSYGTPPDSPGNLLSFPRFFGPGEFDPSVDVYAMKSHESSPKK .:: :.::. ::::::::: :. ..::::::..:::..: ::.::.: NP_005 NDGEEEGESDGTH-----PVGTPPDSPGNTLNSSPPLAPGEFDPNIDVYGIKCHENSPRK 300 310 320 330 340 350 370 380 390 400 410 pF1KB4 EVYFMAIIDILTPYDTKKKAAHAAKTVKHGAGAEISTVNPEQYSKRFNEFMSNILT :::::::::::: ::.::::::::::::::::::::::::::::::: .:...::: NP_005 EVYFMAIIDILTHYDAKKKAAHAAKTVKHGAGAEISTVNPEQYSKRFLDFIGHILT 360 370 380 390 400 >>NP_001316991 (OMIM: 603140) phosphatidylinositol 5-pho (347 aa) initn: 1859 init1: 1377 opt: 1849 Z-score: 2028.2 bits: 384.0 E(85289): 3.1e-106 Smith-Waterman score: 1849; 77.8% identity (92.0% similar) in 352 aa overlap (65-416:1-347) 40 50 60 70 80 90 pF1KB4 LFRASEPILSVLMWGVNHTINELSNVPVPVMLMPDDFKAYSKIKVDNHLFNKENLPSRFK ::::::::::::::::::::::::.::.:: NP_001 MLMPDDFKAYSKIKVDNHLFNKENMPSHFK 10 20 30 100 110 120 130 140 150 pF1KB4 FKEYCPMVFRNLRERFGIDDQDYQNSVTRSAPINSDSQGRCGTRFLTTYDRRFVIKTVSS ::::::::::::::::::::::.:::.:::::. .:::.: :.:: :.::.:..:::..: NP_001 FKEYCPMVFRNLRERFGIDDQDFQNSLTRSAPLPNDSQARSGARFHTSYDKRYIIKTITS 40 50 60 70 80 90 160 170 180 190 200 210 pF1KB4 EDVAEMHNILKKYHQFIVECHGNTLLPQFLGMYRLTVDGVETYMVVTRNVFSHRLTVHRK :::::::::::::::.:::::: ::::::::::::.::::: :..::::::::::.:.:: NP_001 EDVAEMHNILKKYHQYIVECHGITLLPQFLGMYRLNVDGVEIYVIVTRNVFSHRLSVYRK 100 110 120 130 140 150 220 230 240 250 260 270 pF1KB4 YDLKGSTVAREASDKEKAKDLPTFKDNDFLNEGQKLHVGEESKKNFLEKLKRDVEFLAQL :::::::::::::::::::.:::.:::::.:::::... ...:: ::::::.:::::::: NP_001 YDLKGSTVAREASDKEKAKELPTLKDNDFINEGQKIYIDDNNKKVFLEKLKKDVEFLAQL 160 170 180 190 200 210 280 290 300 310 320 330 pF1KB4 KIMDYSLLVGIHDVDRAEQEEMEVEERAEDEECENDGVGGNLLCSYGTPPDSPGNLLSFP :.::::::::::::.::::::.: :: .:: :.::. ::::::::: :. NP_001 KLMDYSLLVGIHDVERAEQEEVECEENDGEEEGESDGTH-----PVGTPPDSPGNTLNSS 220 230 240 250 260 340 350 360 370 380 390 pF1KB4 RFFGPGEFDPSVDVYAMKSHESSPKKEVYFMAIIDILTPYDTKKKAAHAAKTVKHGAGAE ..::::::..:::..: ::.::.::::::::::::: ::.:::::::::::::::::: NP_001 PPLAPGEFDPNIDVYGIKCHENSPRKEVYFMAIIDILTHYDAKKKAAHAAKTVKHGAGAE 270 280 290 300 310 320 400 410 pF1KB4 ISTVNPEQYSKRFNEFMSNILT ::::::::::::: .:...::: NP_001 ISTVNPEQYSKRFLDFIGHILT 330 340 >>XP_016871820 (OMIM: 603140) PREDICTED: phosphatidylino (347 aa) initn: 1859 init1: 1377 opt: 1849 Z-score: 2028.2 bits: 384.0 E(85289): 3.1e-106 Smith-Waterman score: 1849; 77.8% identity (92.0% similar) in 352 aa overlap (65-416:1-347) 40 50 60 70 80 90 pF1KB4 LFRASEPILSVLMWGVNHTINELSNVPVPVMLMPDDFKAYSKIKVDNHLFNKENLPSRFK ::::::::::::::::::::::::.::.:: XP_016 MLMPDDFKAYSKIKVDNHLFNKENMPSHFK 10 20 30 100 110 120 130 140 150 pF1KB4 FKEYCPMVFRNLRERFGIDDQDYQNSVTRSAPINSDSQGRCGTRFLTTYDRRFVIKTVSS ::::::::::::::::::::::.:::.:::::. .:::.: :.:: :.::.:..:::..: XP_016 FKEYCPMVFRNLRERFGIDDQDFQNSLTRSAPLPNDSQARSGARFHTSYDKRYIIKTITS 40 50 60 70 80 90 160 170 180 190 200 210 pF1KB4 EDVAEMHNILKKYHQFIVECHGNTLLPQFLGMYRLTVDGVETYMVVTRNVFSHRLTVHRK :::::::::::::::.:::::: ::::::::::::.::::: :..::::::::::.:.:: XP_016 EDVAEMHNILKKYHQYIVECHGITLLPQFLGMYRLNVDGVEIYVIVTRNVFSHRLSVYRK 100 110 120 130 140 150 220 230 240 250 260 270 pF1KB4 YDLKGSTVAREASDKEKAKDLPTFKDNDFLNEGQKLHVGEESKKNFLEKLKRDVEFLAQL :::::::::::::::::::.:::.:::::.:::::... ...:: ::::::.:::::::: XP_016 YDLKGSTVAREASDKEKAKELPTLKDNDFINEGQKIYIDDNNKKVFLEKLKKDVEFLAQL 160 170 180 190 200 210 280 290 300 310 320 330 pF1KB4 KIMDYSLLVGIHDVDRAEQEEMEVEERAEDEECENDGVGGNLLCSYGTPPDSPGNLLSFP :.::::::::::::.::::::.: :: .:: :.::. ::::::::: :. XP_016 KLMDYSLLVGIHDVERAEQEEVECEENDGEEEGESDGTH-----PVGTPPDSPGNTLNSS 220 230 240 250 260 340 350 360 370 380 390 pF1KB4 RFFGPGEFDPSVDVYAMKSHESSPKKEVYFMAIIDILTPYDTKKKAAHAAKTVKHGAGAE ..::::::..:::..: ::.::.::::::::::::: ::.:::::::::::::::::: XP_016 PPLAPGEFDPNIDVYGIKCHENSPRKEVYFMAIIDILTHYDAKKKAAHAAKTVKHGAGAE 270 280 290 300 310 320 400 410 pF1KB4 ISTVNPEQYSKRFNEFMSNILT ::::::::::::: .:...::: XP_016 ISTVNPEQYSKRFLDFIGHILT 330 340 >>XP_016871819 (OMIM: 603140) PREDICTED: phosphatidylino (347 aa) initn: 1859 init1: 1377 opt: 1849 Z-score: 2028.2 bits: 384.0 E(85289): 3.1e-106 Smith-Waterman score: 1849; 77.8% identity (92.0% similar) in 352 aa overlap (65-416:1-347) 40 50 60 70 80 90 pF1KB4 LFRASEPILSVLMWGVNHTINELSNVPVPVMLMPDDFKAYSKIKVDNHLFNKENLPSRFK ::::::::::::::::::::::::.::.:: XP_016 MLMPDDFKAYSKIKVDNHLFNKENMPSHFK 10 20 30 100 110 120 130 140 150 pF1KB4 FKEYCPMVFRNLRERFGIDDQDYQNSVTRSAPINSDSQGRCGTRFLTTYDRRFVIKTVSS ::::::::::::::::::::::.:::.:::::. .:::.: :.:: :.::.:..:::..: XP_016 FKEYCPMVFRNLRERFGIDDQDFQNSLTRSAPLPNDSQARSGARFHTSYDKRYIIKTITS 40 50 60 70 80 90 160 170 180 190 200 210 pF1KB4 EDVAEMHNILKKYHQFIVECHGNTLLPQFLGMYRLTVDGVETYMVVTRNVFSHRLTVHRK :::::::::::::::.:::::: ::::::::::::.::::: :..::::::::::.:.:: XP_016 EDVAEMHNILKKYHQYIVECHGITLLPQFLGMYRLNVDGVEIYVIVTRNVFSHRLSVYRK 100 110 120 130 140 150 220 230 240 250 260 270 pF1KB4 YDLKGSTVAREASDKEKAKDLPTFKDNDFLNEGQKLHVGEESKKNFLEKLKRDVEFLAQL :::::::::::::::::::.:::.:::::.:::::... ...:: ::::::.:::::::: XP_016 YDLKGSTVAREASDKEKAKELPTLKDNDFINEGQKIYIDDNNKKVFLEKLKKDVEFLAQL 160 170 180 190 200 210 280 290 300 310 320 330 pF1KB4 KIMDYSLLVGIHDVDRAEQEEMEVEERAEDEECENDGVGGNLLCSYGTPPDSPGNLLSFP :.::::::::::::.::::::.: :: .:: :.::. ::::::::: :. XP_016 KLMDYSLLVGIHDVERAEQEEVECEENDGEEEGESDGTH-----PVGTPPDSPGNTLNSS 220 230 240 250 260 340 350 360 370 380 390 pF1KB4 RFFGPGEFDPSVDVYAMKSHESSPKKEVYFMAIIDILTPYDTKKKAAHAAKTVKHGAGAE ..::::::..:::..: ::.::.::::::::::::: ::.:::::::::::::::::: XP_016 PPLAPGEFDPNIDVYGIKCHENSPRKEVYFMAIIDILTHYDAKKKAAHAAKTVKHGAGAE 270 280 290 300 310 320 400 410 pF1KB4 ISTVNPEQYSKRFNEFMSNILT ::::::::::::: .:...::: XP_016 ISTVNPEQYSKRFLDFIGHILT 330 340 >>NP_079055 (OMIM: 617104) phosphatidylinositol 5-phosph (421 aa) initn: 1581 init1: 803 opt: 1782 Z-score: 1953.6 bits: 370.5 E(85289): 4.5e-102 Smith-Waterman score: 1782; 65.0% identity (85.7% similar) in 420 aa overlap (2-415:4-420) 10 20 30 40 50 pF1KB4 MSSNCTSTTAVAVA---PLSASKTKTKKKHFVCQKVKLFRASEPILSVLMWGVNHTIN :: .:...:.: : . .:::::::: ::::.:::..:...:..::: :.:: NP_079 MASSSVPPATVSAATAGPGPGFGFASKTKKKHFVQQKVKVFRAADPLVGVFLWGVAHSIN 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB4 ELSNVPVPVMLMPDDFKAYSKIKVDNHLFNKENLPSRFKFKEYCPMVFRNLRERFGIDDQ :::.:: ::::.:::::: :::::.::::..:::::.::::::::.::::::.::::::: NP_079 ELSQVPPPVMLLPDDFKASSKIKVNNHLFHRENLPSHFKFKEYCPQVFRNLRDRFGIDDQ 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB4 DYQNSVTRSAPINSDSQGRCGTRFLTTYDRRFVIKTVSSEDVAEMHNILKKYHQFIVECH :: :.::. : :.:.: : ::: .::: .::: :::::.:.::. :..:::.::.:: NP_079 DYLVSLTRNPP--SESEGSDG-RFLISYDRTLVIKEVSSEDIADMHSNLSNYHQYIVKCH 130 140 150 160 170 180 190 200 210 220 230 pF1KB4 GNTLLPQFLGMYRLTVDGVETYMVVTRNVFSHRLTVHRKYDLKGSTVAREASDKEKAKDL :::::::::::::..::. ..::.: ::.::::: :::::::::: :.::::::::.:.: NP_079 GNTLLPQFLGMYRVSVDNEDSYMLVMRNMFSHRLPVHRKYDLKGSLVSREASDKEKVKEL 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB4 PTFKDNDFLNEGQKLHVGEESKKNFLEKLKRDVEFLAQLKIMDYSLLVGIHDVDRAEQEE ::.:: ::::..::...::: :: ::::::::::::.::::::::::.::::. :. . : NP_079 PTLKDMDFLNKNQKVYIGEEEKKIFLEKLKRDVEFLVQLKIMDYSLLLGIHDIIRGSEPE 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB4 MEVEERAEDEECEND-GVGG--NLLCSYGTPPDSPGNLLSFPRFFGPGEFDPSVDVYAMK :. : .. : ..: .. : :. :::: :.. :. . : .:::::. .::::.. NP_079 EEAPVREDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIHSHRPLGPGEFESFIDVYAIR 300 310 320 330 340 350 360 370 380 390 400 410 pF1KB4 SHESSPKKEVYFMAIIDILTPYDTKKKAAHAAKTVKHGAGAEISTVNPEQYSKRFNEFMS : :..:.::::::..::::: ::.::::::::::::::::::::::.::::.::: .:.. NP_079 SAEGAPQKEVYFMGLIDILTQYDAKKKAAHAAKTVKHGAGAEISTVHPEQYAKRFLDFIT 360 370 380 390 400 410 pF1KB4 NILT ::. NP_079 NIFA 420 >>NP_001139730 (OMIM: 617104) phosphatidylinositol 5-pho (421 aa) initn: 1581 init1: 803 opt: 1782 Z-score: 1953.6 bits: 370.5 E(85289): 4.5e-102 Smith-Waterman score: 1782; 65.0% identity (85.7% similar) in 420 aa overlap (2-415:4-420) 10 20 30 40 50 pF1KB4 MSSNCTSTTAVAVA---PLSASKTKTKKKHFVCQKVKLFRASEPILSVLMWGVNHTIN :: .:...:.: : . .:::::::: ::::.:::..:...:..::: :.:: NP_001 MASSSVPPATVSAATAGPGPGFGFASKTKKKHFVQQKVKVFRAADPLVGVFLWGVAHSIN 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB4 ELSNVPVPVMLMPDDFKAYSKIKVDNHLFNKENLPSRFKFKEYCPMVFRNLRERFGIDDQ :::.:: ::::.:::::: :::::.::::..:::::.::::::::.::::::.::::::: NP_001 ELSQVPPPVMLLPDDFKASSKIKVNNHLFHRENLPSHFKFKEYCPQVFRNLRDRFGIDDQ 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB4 DYQNSVTRSAPINSDSQGRCGTRFLTTYDRRFVIKTVSSEDVAEMHNILKKYHQFIVECH :: :.::. : :.:.: : ::: .::: .::: :::::.:.::. :..:::.::.:: NP_001 DYLVSLTRNPP--SESEGSDG-RFLISYDRTLVIKEVSSEDIADMHSNLSNYHQYIVKCH 130 140 150 160 170 180 190 200 210 220 230 pF1KB4 GNTLLPQFLGMYRLTVDGVETYMVVTRNVFSHRLTVHRKYDLKGSTVAREASDKEKAKDL :::::::::::::..::. ..::.: ::.::::: :::::::::: :.::::::::.:.: NP_001 GNTLLPQFLGMYRVSVDNEDSYMLVMRNMFSHRLPVHRKYDLKGSLVSREASDKEKVKEL 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB4 PTFKDNDFLNEGQKLHVGEESKKNFLEKLKRDVEFLAQLKIMDYSLLVGIHDVDRAEQEE ::.:: ::::..::...::: :: ::::::::::::.::::::::::.::::. :. . : NP_001 PTLKDMDFLNKNQKVYIGEEEKKIFLEKLKRDVEFLVQLKIMDYSLLLGIHDIIRGSEPE 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB4 MEVEERAEDEECEND-GVGG--NLLCSYGTPPDSPGNLLSFPRFFGPGEFDPSVDVYAMK :. : .. : ..: .. : :. :::: :.. :. . : .:::::. .::::.. NP_001 EEAPVREDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIHSHRPLGPGEFESFIDVYAIR 300 310 320 330 340 350 360 370 380 390 400 410 pF1KB4 SHESSPKKEVYFMAIIDILTPYDTKKKAAHAAKTVKHGAGAEISTVNPEQYSKRFNEFMS : :..:.::::::..::::: ::.::::::::::::::::::::::.::::.::: .:.. NP_001 SAEGAPQKEVYFMGLIDILTQYDAKKKAAHAAKTVKHGAGAEISTVHPEQYAKRFLDFIT 360 370 380 390 400 410 pF1KB4 NILT ::. NP_001 NIFA 420 >>XP_016880687 (OMIM: 603261) PREDICTED: phosphatidylino (257 aa) initn: 1705 init1: 1705 opt: 1705 Z-score: 1872.8 bits: 354.8 E(85289): 1.4e-97 Smith-Waterman score: 1705; 100.0% identity (100.0% similar) in 257 aa overlap (160-416:1-257) 130 140 150 160 170 180 pF1KB4 DSQGRCGTRFLTTYDRRFVIKTVSSEDVAEMHNILKKYHQFIVECHGNTLLPQFLGMYRL :::::::::::::::::::::::::::::: XP_016 MHNILKKYHQFIVECHGNTLLPQFLGMYRL 10 20 30 190 200 210 220 230 240 pF1KB4 TVDGVETYMVVTRNVFSHRLTVHRKYDLKGSTVAREASDKEKAKDLPTFKDNDFLNEGQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TVDGVETYMVVTRNVFSHRLTVHRKYDLKGSTVAREASDKEKAKDLPTFKDNDFLNEGQK 40 50 60 70 80 90 250 260 270 280 290 300 pF1KB4 LHVGEESKKNFLEKLKRDVEFLAQLKIMDYSLLVGIHDVDRAEQEEMEVEERAEDEECEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LHVGEESKKNFLEKLKRDVEFLAQLKIMDYSLLVGIHDVDRAEQEEMEVEERAEDEECEN 100 110 120 130 140 150 310 320 330 340 350 360 pF1KB4 DGVGGNLLCSYGTPPDSPGNLLSFPRFFGPGEFDPSVDVYAMKSHESSPKKEVYFMAIID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DGVGGNLLCSYGTPPDSPGNLLSFPRFFGPGEFDPSVDVYAMKSHESSPKKEVYFMAIID 160 170 180 190 200 210 370 380 390 400 410 pF1KB4 ILTPYDTKKKAAHAAKTVKHGAGAEISTVNPEQYSKRFNEFMSNILT ::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ILTPYDTKKKAAHAAKTVKHGAGAEISTVNPEQYSKRFNEFMSNILT 220 230 240 250 >>XP_011523632 (OMIM: 603261) PREDICTED: phosphatidylino (284 aa) initn: 1640 init1: 1640 opt: 1640 Z-score: 1801.0 bits: 341.7 E(85289): 1.4e-93 Smith-Waterman score: 1641; 90.5% identity (90.5% similar) in 284 aa overlap (160-416:1-284) 130 140 150 160 pF1KB4 DSQGRCGTRFLTTYDRRFVIKTVSSEDVAEMHNILKKYHQ-------------------- :::::::::: XP_011 MHNILKKYHQMAGSLACLCILSLPCGIPIS 10 20 30 170 180 190 200 210 220 pF1KB4 -------FIVECHGNTLLPQFLGMYRLTVDGVETYMVVTRNVFSHRLTVHRKYDLKGSTV ::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GWQKRCKFIVECHGNTLLPQFLGMYRLTVDGVETYMVVTRNVFSHRLTVHRKYDLKGSTV 40 50 60 70 80 90 230 240 250 260 270 280 pF1KB4 AREASDKEKAKDLPTFKDNDFLNEGQKLHVGEESKKNFLEKLKRDVEFLAQLKIMDYSLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AREASDKEKAKDLPTFKDNDFLNEGQKLHVGEESKKNFLEKLKRDVEFLAQLKIMDYSLL 100 110 120 130 140 150 290 300 310 320 330 340 pF1KB4 VGIHDVDRAEQEEMEVEERAEDEECENDGVGGNLLCSYGTPPDSPGNLLSFPRFFGPGEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VGIHDVDRAEQEEMEVEERAEDEECENDGVGGNLLCSYGTPPDSPGNLLSFPRFFGPGEF 160 170 180 190 200 210 350 360 370 380 390 400 pF1KB4 DPSVDVYAMKSHESSPKKEVYFMAIIDILTPYDTKKKAAHAAKTVKHGAGAEISTVNPEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DPSVDVYAMKSHESSPKKEVYFMAIIDILTPYDTKKKAAHAAKTVKHGAGAEISTVNPEQ 220 230 240 250 260 270 410 pF1KB4 YSKRFNEFMSNILT :::::::::::::: XP_011 YSKRFNEFMSNILT 280 416 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 05:43:30 2016 done: Sat Nov 5 05:43:31 2016 Total Scan time: 7.600 Total Display time: 0.040 Function used was FASTA [36.3.4 Apr, 2011]