FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB4240, 471 aa 1>>>pF1KB4240 471 - 471 aa - 471 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 13.1371+/-0.000397; mu= -19.3734+/- 0.025 mean_var=353.8349+/-74.531, 0's: 0 Z-trim(123.4): 128 B-trim: 1985 in 1/58 Lambda= 0.068183 statistics sampled from 42920 (43049) to 42920 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.78), E-opt: 0.2 (0.505), width: 16 Scan time: 12.370 The best scores are: opt bits E(85289) XP_016859629 (OMIM: 157130) PREDICTED: microtubule ( 471) 3051 313.6 7.2e-85 NP_114033 (OMIM: 157130) microtubule-associated pr ( 471) 3051 313.6 7.2e-85 NP_114035 (OMIM: 157130) microtubule-associated pr ( 502) 2464 255.9 1.8e-67 XP_016859626 (OMIM: 157130) PREDICTED: microtubule (1668) 2079 218.2 1.4e-55 XP_016859615 (OMIM: 157130) PREDICTED: microtubule (1822) 2079 218.2 1.5e-55 XP_016859610 (OMIM: 157130) PREDICTED: microtubule (1826) 2079 218.2 1.5e-55 XP_016859618 (OMIM: 157130) PREDICTED: microtubule (1820) 2075 217.8 1.9e-55 XP_016859622 (OMIM: 157130) PREDICTED: microtubule (1669) 2072 217.5 2.2e-55 XP_016859624 (OMIM: 157130) PREDICTED: microtubule (1669) 2072 217.5 2.2e-55 XP_016859623 (OMIM: 157130) PREDICTED: microtubule (1669) 2072 217.5 2.2e-55 XP_016859616 (OMIM: 157130) PREDICTED: microtubule (1822) 2072 217.5 2.4e-55 XP_016859612 (OMIM: 157130) PREDICTED: microtubule (1823) 2072 217.5 2.4e-55 XP_016859613 (OMIM: 157130) PREDICTED: microtubule (1823) 2072 217.5 2.4e-55 XP_016859609 (OMIM: 157130) PREDICTED: microtubule (1826) 2072 217.6 2.4e-55 XP_016859611 (OMIM: 157130) PREDICTED: microtubule (1826) 2072 217.6 2.4e-55 NP_002365 (OMIM: 157130) microtubule-associated pr (1827) 2072 217.6 2.4e-55 XP_016859607 (OMIM: 157130) PREDICTED: microtubule (1827) 2072 217.6 2.4e-55 XP_016859625 (OMIM: 157130) PREDICTED: microtubule (1668) 2069 217.2 2.7e-55 XP_016859617 (OMIM: 157130) PREDICTED: microtubule (1821) 2069 217.3 2.9e-55 XP_016859614 (OMIM: 157130) PREDICTED: microtubule (1822) 2069 217.3 2.9e-55 XP_016859608 (OMIM: 157130) PREDICTED: microtubule (1826) 2069 217.3 2.9e-55 XP_011509492 (OMIM: 157130) PREDICTED: microtubule (1966) 1958 206.3 6e-52 XP_016859605 (OMIM: 157130) PREDICTED: microtubule (1853) 1492 160.5 3.6e-38 XP_011509495 (OMIM: 157130) PREDICTED: microtubule (1939) 1492 160.5 3.8e-38 XP_016859621 (OMIM: 157130) PREDICTED: microtubule (1700) 1485 159.8 5.4e-38 XP_016859620 (OMIM: 157130) PREDICTED: microtubule (1700) 1485 159.8 5.4e-38 XP_016859606 (OMIM: 157130) PREDICTED: microtubule (1853) 1485 159.8 5.8e-38 XP_016859604 (OMIM: 157130) PREDICTED: microtubule (1854) 1485 159.8 5.8e-38 XP_016859603 (OMIM: 157130) PREDICTED: microtubule (1858) 1485 159.8 5.8e-38 XP_011509494 (OMIM: 157130) PREDICTED: microtubule (1940) 1485 159.8 6e-38 XP_016859600 (OMIM: 157130) PREDICTED: microtubule (1939) 1482 159.5 7.4e-38 XP_016859628 (OMIM: 157130) PREDICTED: microtubule ( 559) 1371 148.4 4.7e-35 NP_001034627 (OMIM: 157130) microtubule-associated ( 559) 1371 148.4 4.7e-35 XP_016859627 (OMIM: 157130) PREDICTED: microtubule ( 559) 1371 148.4 4.7e-35 XP_005246623 (OMIM: 157130) PREDICTED: microtubule (1757) 1371 148.6 1.3e-34 XP_016859619 (OMIM: 157130) PREDICTED: microtubule (1757) 1371 148.6 1.3e-34 XP_005246622 (OMIM: 157130) PREDICTED: microtubule (1757) 1371 148.6 1.3e-34 XP_016859602 (OMIM: 157130) PREDICTED: microtubule (1910) 1371 148.6 1.4e-34 XP_011509499 (OMIM: 157130) PREDICTED: microtubule (1910) 1371 148.6 1.4e-34 XP_011509498 (OMIM: 157130) PREDICTED: microtubule (1911) 1371 148.6 1.4e-34 XP_011509497 (OMIM: 157130) PREDICTED: microtubule (1914) 1371 148.6 1.4e-34 XP_016859601 (OMIM: 157130) PREDICTED: microtubule (1915) 1371 148.6 1.4e-34 XP_011509493 (OMIM: 157130) PREDICTED: microtubule (1952) 1371 148.6 1.4e-34 XP_006712595 (OMIM: 157130) PREDICTED: microtubule (1996) 1371 148.6 1.5e-34 XP_011509490 (OMIM: 157130) PREDICTED: microtubule (1996) 1371 148.6 1.5e-34 XP_011509489 (OMIM: 157130) PREDICTED: microtubule (1996) 1371 148.6 1.5e-34 XP_011509488 (OMIM: 157130) PREDICTED: microtubule (1997) 1371 148.6 1.5e-34 XP_005246612 (OMIM: 157130) PREDICTED: microtubule (1997) 1371 148.6 1.5e-34 NP_001190180 (OMIM: 157140,168600,172700,260540,60 ( 381) 961 108.0 4.6e-23 XP_005257422 (OMIM: 157140,168600,172700,260540,60 ( 831) 953 107.4 1.6e-22 >>XP_016859629 (OMIM: 157130) PREDICTED: microtubule-ass (471 aa) initn: 3051 init1: 3051 opt: 3051 Z-score: 1644.6 bits: 313.6 E(85289): 7.2e-85 Smith-Waterman score: 3051; 100.0% identity (100.0% similar) in 471 aa overlap (1-471:1-471) 10 20 30 40 50 60 pF1KB4 MADERKDEAKAPHWTSAPLTEASAHSHPPEIKDQGGAGEGLVRSANGFPYREDEEGAFGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MADERKDEAKAPHWTSAPLTEASAHSHPPEIKDQGGAGEGLVRSANGFPYREDEEGAFGE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 HGSQGTYSNTKENGINGELTSADRETAEEVSARIVQVVTAEAVAVLKGEQEKEAQHKDQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HGSQGTYSNTKENGINGELTSADRETAEEVSARIVQVVTAEAVAVLKGEQEKEAQHKDQT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 AALPLAAEETANLPPSPPPSPASEQTVTVEEAAGGESALAPSVFKQAKDKVSDGVTKSPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AALPLAAEETANLPPSPPPSPASEQTVTVEEAAGGESALAPSVFKQAKDKVSDGVTKSPE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 KRSSLPRPSSILPPRRGVSGDRDENSFSLNSSISSSARRTTRSEPIRRAGKSGTSTPTTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KRSSLPRPSSILPPRRGVSGDRDENSFSLNSSISSSARRTTRSEPIRRAGKSGTSTPTTP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 GSTAITPGTPPSYSSRTPGTPGTPSYPRTPHTPGTPKSAILVPSEKKVAIIRTPPKSPAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GSTAITPGTPPSYSSRTPGTPGTPSYPRTPHTPGTPKSAILVPSEKKVAIIRTPPKSPAT 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 PKQLRLINQPLPDLKNVKSKIGSTDNIKYQPKGGQVQIVTKKIDLSHVTSKCGSLKNIRH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PKQLRLINQPLPDLKNVKSKIGSTDNIKYQPKGGQVQIVTKKIDLSHVTSKCGSLKNIRH 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB4 RPGGGRVKIESVKLDFKEKAQAKVGSLDNAHHVPGGGNVKIDSQKLNFREHAKARVDHGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RPGGGRVKIESVKLDFKEKAQAKVGSLDNAHHVPGGGNVKIDSQKLNFREHAKARVDHGA 370 380 390 400 410 420 430 440 450 460 470 pF1KB4 EIITQSPGRSSVASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL ::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EIITQSPGRSSVASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL 430 440 450 460 470 >>NP_114033 (OMIM: 157130) microtubule-associated protei (471 aa) initn: 3051 init1: 3051 opt: 3051 Z-score: 1644.6 bits: 313.6 E(85289): 7.2e-85 Smith-Waterman score: 3051; 100.0% identity (100.0% similar) in 471 aa overlap (1-471:1-471) 10 20 30 40 50 60 pF1KB4 MADERKDEAKAPHWTSAPLTEASAHSHPPEIKDQGGAGEGLVRSANGFPYREDEEGAFGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_114 MADERKDEAKAPHWTSAPLTEASAHSHPPEIKDQGGAGEGLVRSANGFPYREDEEGAFGE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 HGSQGTYSNTKENGINGELTSADRETAEEVSARIVQVVTAEAVAVLKGEQEKEAQHKDQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_114 HGSQGTYSNTKENGINGELTSADRETAEEVSARIVQVVTAEAVAVLKGEQEKEAQHKDQT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 AALPLAAEETANLPPSPPPSPASEQTVTVEEAAGGESALAPSVFKQAKDKVSDGVTKSPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_114 AALPLAAEETANLPPSPPPSPASEQTVTVEEAAGGESALAPSVFKQAKDKVSDGVTKSPE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 KRSSLPRPSSILPPRRGVSGDRDENSFSLNSSISSSARRTTRSEPIRRAGKSGTSTPTTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_114 KRSSLPRPSSILPPRRGVSGDRDENSFSLNSSISSSARRTTRSEPIRRAGKSGTSTPTTP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 GSTAITPGTPPSYSSRTPGTPGTPSYPRTPHTPGTPKSAILVPSEKKVAIIRTPPKSPAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_114 GSTAITPGTPPSYSSRTPGTPGTPSYPRTPHTPGTPKSAILVPSEKKVAIIRTPPKSPAT 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 PKQLRLINQPLPDLKNVKSKIGSTDNIKYQPKGGQVQIVTKKIDLSHVTSKCGSLKNIRH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_114 PKQLRLINQPLPDLKNVKSKIGSTDNIKYQPKGGQVQIVTKKIDLSHVTSKCGSLKNIRH 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB4 RPGGGRVKIESVKLDFKEKAQAKVGSLDNAHHVPGGGNVKIDSQKLNFREHAKARVDHGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_114 RPGGGRVKIESVKLDFKEKAQAKVGSLDNAHHVPGGGNVKIDSQKLNFREHAKARVDHGA 370 380 390 400 410 420 430 440 450 460 470 pF1KB4 EIITQSPGRSSVASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL ::::::::::::::::::::::::::::::::::::::::::::::::::: NP_114 EIITQSPGRSSVASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL 430 440 450 460 470 >>NP_114035 (OMIM: 157130) microtubule-associated protei (502 aa) initn: 2463 init1: 2338 opt: 2464 Z-score: 1332.1 bits: 255.9 E(85289): 1.8e-67 Smith-Waterman score: 2979; 93.8% identity (93.8% similar) in 502 aa overlap (1-471:1-502) 10 20 30 40 50 60 pF1KB4 MADERKDEAKAPHWTSAPLTEASAHSHPPEIKDQGGAGEGLVRSANGFPYREDEEGAFGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_114 MADERKDEAKAPHWTSAPLTEASAHSHPPEIKDQGGAGEGLVRSANGFPYREDEEGAFGE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 HGSQGTYSNTKENGINGELTSADRETAEEVSARIVQVVTAEAVAVLKGEQEKEAQHKDQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_114 HGSQGTYSNTKENGINGELTSADRETAEEVSARIVQVVTAEAVAVLKGEQEKEAQHKDQT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 AALPLAAEETANLPPSPPPSPASEQTVTVEEAAGGESALAPSVFKQAKDKVSDGVTKSPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_114 AALPLAAEETANLPPSPPPSPASEQTVTVEEAAGGESALAPSVFKQAKDKVSDGVTKSPE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 KRSSLPRPSSILPPRRGVSGDRDENSFSLNSSISSSARRTTRSEPIRRAGKSGTSTPTTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_114 KRSSLPRPSSILPPRRGVSGDRDENSFSLNSSISSSARRTTRSEPIRRAGKSGTSTPTTP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 GSTAITPGTPPSYSSRTPGTPGTPSYPRTPHTPGTPKSAILVPSEKKVAIIRTPPKSPAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_114 GSTAITPGTPPSYSSRTPGTPGTPSYPRTPHTPGTPKSAILVPSEKKVAIIRTPPKSPAT 250 260 270 280 290 300 310 320 330 pF1KB4 PKQLRLINQPLPDLKNVKSKIGSTDNIKYQPKGGQV------------------------ :::::::::::::::::::::::::::::::::::: NP_114 PKQLRLINQPLPDLKNVKSKIGSTDNIKYQPKGGQVRILNKKIDFSKVQSRCGSKDNIKH 310 320 330 340 350 360 340 350 360 370 380 pF1KB4 -------QIVTKKIDLSHVTSKCGSLKNIRHRPGGGRVKIESVKLDFKEKAQAKVGSLDN ::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_114 SAGGGNVQIVTKKIDLSHVTSKCGSLKNIRHRPGGGRVKIESVKLDFKEKAQAKVGSLDN 370 380 390 400 410 420 390 400 410 420 430 440 pF1KB4 AHHVPGGGNVKIDSQKLNFREHAKARVDHGAEIITQSPGRSSVASPRRLSNVSSSGSINL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_114 AHHVPGGGNVKIDSQKLNFREHAKARVDHGAEIITQSPGRSSVASPRRLSNVSSSGSINL 430 440 450 460 470 480 450 460 470 pF1KB4 LESPQLATLAEDVTAALAKQGL :::::::::::::::::::::: NP_114 LESPQLATLAEDVTAALAKQGL 490 500 >>XP_016859626 (OMIM: 157130) PREDICTED: microtubule-ass (1668 aa) initn: 2065 init1: 2065 opt: 2079 Z-score: 1119.0 bits: 218.2 E(85289): 1.4e-55 Smith-Waterman score: 2079; 80.0% identity (87.9% similar) in 421 aa overlap (54-471:1252-1668) 30 40 50 60 70 80 pF1KB4 AHSHPPEIKDQGGAGEGLVRSANGFPYREDEEGAFGEHGSQGTYSNTKENGIN---GELT :: : : .. .. ::. .. :... XP_016 DSIMDADSLWVDTQDDDRSIMTEQLETIPKEEKAEKEARRSSLEKHRKEKPFKTGRGRIS 1230 1240 1250 1260 1270 1280 90 100 110 120 130 140 pF1KB4 SADRETAEEVSARIVQVVTAEAVAVLKGEQEKEAQHKDQTAALPLAAEETANLPPSPPPS . .:..:.. . . . . . :: : . . :.. . : : ... : XP_016 TPERKVAKKEPSTVSRDEVRRKKAVYK--KAELAKKTEVQAHSP--SRKFILKPAIKYTR 1290 1300 1310 1320 1330 150 160 170 180 190 200 pF1KB4 PASEQTVTVEEAAGGESALAPSVFKQAKDKVSDGVTKSPEKRSSLPRPSSILPPRRGVSG :. . : . .:::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PTHLSCVKRKTTAGGESALAPSVFKQAKDKVSDGVTKSPEKRSSLPRPSSILPPRRGVSG 1340 1350 1360 1370 1380 1390 210 220 230 240 250 260 pF1KB4 DRDENSFSLNSSISSSARRTTRSEPIRRAGKSGTSTPTTPGSTAITPGTPPSYSSRTPGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DRDENSFSLNSSISSSARRTTRSEPIRRAGKSGTSTPTTPGSTAITPGTPPSYSSRTPGT 1400 1410 1420 1430 1440 1450 270 280 290 300 310 320 pF1KB4 PGTPSYPRTPHTPGTPKSAILVPSEKKVAIIRTPPKSPATPKQLRLINQPLPDLKNVKSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PGTPSYPRTPHTPGTPKSAILVPSEKKVAIIRTPPKSPATPKQLRLINQPLPDLKNVKSK 1460 1470 1480 1490 1500 1510 330 340 350 360 370 380 pF1KB4 IGSTDNIKYQPKGGQVQIVTKKIDLSHVTSKCGSLKNIRHRPGGGRVKIESVKLDFKEKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IGSTDNIKYQPKGGQVQIVTKKIDLSHVTSKCGSLKNIRHRPGGGRVKIESVKLDFKEKA 1520 1530 1540 1550 1560 1570 390 400 410 420 430 440 pF1KB4 QAKVGSLDNAHHVPGGGNVKIDSQKLNFREHAKARVDHGAEIITQSPGRSSVASPRRLSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QAKVGSLDNAHHVPGGGNVKIDSQKLNFREHAKARVDHGAEIITQSPGRSSVASPRRLSN 1580 1590 1600 1610 1620 1630 450 460 470 pF1KB4 VSSSGSINLLESPQLATLAEDVTAALAKQGL ::::::::::::::::::::::::::::::: XP_016 VSSSGSINLLESPQLATLAEDVTAALAKQGL 1640 1650 1660 >>XP_016859615 (OMIM: 157130) PREDICTED: microtubule-ass (1822 aa) initn: 2065 init1: 2065 opt: 2079 Z-score: 1118.4 bits: 218.2 E(85289): 1.5e-55 Smith-Waterman score: 2079; 80.0% identity (87.9% similar) in 421 aa overlap (54-471:1406-1822) 30 40 50 60 70 80 pF1KB4 AHSHPPEIKDQGGAGEGLVRSANGFPYREDEEGAFGEHGSQGTYSNTKENGIN---GELT :: : : .. .. ::. .. :... XP_016 DSIMDADSLWVDTQDDDRSIMTEQLETIPKEEKAEKEARRSSLEKHRKEKPFKTGRGRIS 1380 1390 1400 1410 1420 1430 90 100 110 120 130 140 pF1KB4 SADRETAEEVSARIVQVVTAEAVAVLKGEQEKEAQHKDQTAALPLAAEETANLPPSPPPS . .:..:.. . . . . . :: : . . :.. . : : ... : XP_016 TPERKVAKKEPSTVSRDEVRRKKAVYK--KAELAKKTEVQAHSP--SRKFILKPAIKYTR 1440 1450 1460 1470 1480 1490 150 160 170 180 190 200 pF1KB4 PASEQTVTVEEAAGGESALAPSVFKQAKDKVSDGVTKSPEKRSSLPRPSSILPPRRGVSG :. . : . .:::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PTHLSCVKRKTTAGGESALAPSVFKQAKDKVSDGVTKSPEKRSSLPRPSSILPPRRGVSG 1500 1510 1520 1530 1540 1550 210 220 230 240 250 260 pF1KB4 DRDENSFSLNSSISSSARRTTRSEPIRRAGKSGTSTPTTPGSTAITPGTPPSYSSRTPGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DRDENSFSLNSSISSSARRTTRSEPIRRAGKSGTSTPTTPGSTAITPGTPPSYSSRTPGT 1560 1570 1580 1590 1600 1610 270 280 290 300 310 320 pF1KB4 PGTPSYPRTPHTPGTPKSAILVPSEKKVAIIRTPPKSPATPKQLRLINQPLPDLKNVKSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PGTPSYPRTPHTPGTPKSAILVPSEKKVAIIRTPPKSPATPKQLRLINQPLPDLKNVKSK 1620 1630 1640 1650 1660 1670 330 340 350 360 370 380 pF1KB4 IGSTDNIKYQPKGGQVQIVTKKIDLSHVTSKCGSLKNIRHRPGGGRVKIESVKLDFKEKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IGSTDNIKYQPKGGQVQIVTKKIDLSHVTSKCGSLKNIRHRPGGGRVKIESVKLDFKEKA 1680 1690 1700 1710 1720 1730 390 400 410 420 430 440 pF1KB4 QAKVGSLDNAHHVPGGGNVKIDSQKLNFREHAKARVDHGAEIITQSPGRSSVASPRRLSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QAKVGSLDNAHHVPGGGNVKIDSQKLNFREHAKARVDHGAEIITQSPGRSSVASPRRLSN 1740 1750 1760 1770 1780 1790 450 460 470 pF1KB4 VSSSGSINLLESPQLATLAEDVTAALAKQGL ::::::::::::::::::::::::::::::: XP_016 VSSSGSINLLESPQLATLAEDVTAALAKQGL 1800 1810 1820 >-- initn: 1028 init1: 989 opt: 1035 Z-score: 563.4 bits: 115.5 E(85289): 1.2e-24 Smith-Waterman score: 1035; 57.4% identity (72.2% similar) in 331 aa overlap (1-316:1-327) 10 20 30 40 50 60 pF1KB4 MADERKDEAKAPHWTSAPLTEASAHSHPPEIKDQGGAGEGLVRSANGFPYREDEEGAFGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MADERKDEAKAPHWTSAPLTEASAHSHPPEIKDQGGAGEGLVRSANGFPYREDEEGAFGE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 HGSQGTYSNTKENGINGELTSADRETAEEVSARIVQVVTAEAVAVLKGEQEKEAQHKDQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HGSQGTYSNTKENGINGELTSADRETAEEVSARIVQVVTAEAVAVLKGEQEKEAQHKDQT 70 80 90 100 110 120 130 140 150 160 170 pF1KB4 AALPLAAEETANLPPSPPPSPASEQTVTVEEAAGGE----SALAPSVFKQA--KDKVSDG ::::::::::::::::::::::::::::::::. : . :.::. . . :.: :. XP_016 AALPLAAEETANLPPSPPPSPASEQTVTVEEASKMEFHDQQELTPSTAEPSDQKEKESEK 130 140 150 160 170 180 180 190 200 210 220 pF1KB4 VTKSPE--KRSSL---PRPSSILPPRRGVSGDRDENS-FSL--NSSISSSARRTTRSEP- .: : :...: :. .. : .. ..: ..:.. ..: .. ..: ..:: XP_016 QSKPGEDLKHAALVSQPETTKTYPDKKDMQGTEEEKAPLALFGHTLVASLEDMKQKTEPS 190 200 210 220 230 240 230 240 250 260 270 280 pF1KB4 IRRAGKSGTSTPTTPGSTAITPGTPPSYSSRTPGTPGTPSYPRTPHTPGTPKSAILVPSE . : . . : :: :. ... .: : : :: :... . XP_016 LVVPGIDLPKEPPTPKEQKDWFIEMPTEAKKDEWGLVAPISP-GPLTPMREKDVFDDIPK 250 260 270 280 290 290 300 310 320 330 340 pF1KB4 KKVAIIRTPPKSPATPKQLRLINQPLPDLKNVKSKIGSTDNIKYQPKGGQVQIVTKKIDL . . .: :: .. : :: .:: XP_016 WEGKQFDSPMPSPFQGGSFTL---PLDVMKNEIVTETSPFAPAFLQPDDKKSLQQTSGPA 300 310 320 330 340 350 350 360 370 380 390 400 pF1KB4 SHVTSKCGSLKNIRHRPGGGRVKIESVKLDFKEKAQAKVGSLDNAHHVPGGGNVKIDSQK XP_016 TAKDSFKIEEPHEAKPDKMAEAPPSEAMTLPKDAHIPVVEEHVMGKVLEEEKEAINQETV 360 370 380 390 400 410 >>XP_016859610 (OMIM: 157130) PREDICTED: microtubule-ass (1826 aa) initn: 2065 init1: 2065 opt: 2079 Z-score: 1118.4 bits: 218.2 E(85289): 1.5e-55 Smith-Waterman score: 2079; 80.0% identity (87.9% similar) in 421 aa overlap (54-471:1410-1826) 30 40 50 60 70 80 pF1KB4 AHSHPPEIKDQGGAGEGLVRSANGFPYREDEEGAFGEHGSQGTYSNTKENGIN---GELT :: : : .. .. ::. .. :... XP_016 DSIMDADSLWVDTQDDDRSIMTEQLETIPKEEKAEKEARRSSLEKHRKEKPFKTGRGRIS 1380 1390 1400 1410 1420 1430 90 100 110 120 130 140 pF1KB4 SADRETAEEVSARIVQVVTAEAVAVLKGEQEKEAQHKDQTAALPLAAEETANLPPSPPPS . .:..:.. . . . . . :: : . . :.. . : : ... : XP_016 TPERKVAKKEPSTVSRDEVRRKKAVYK--KAELAKKTEVQAHSP--SRKFILKPAIKYTR 1440 1450 1460 1470 1480 1490 150 160 170 180 190 200 pF1KB4 PASEQTVTVEEAAGGESALAPSVFKQAKDKVSDGVTKSPEKRSSLPRPSSILPPRRGVSG :. . : . .:::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PTHLSCVKRKTTAGGESALAPSVFKQAKDKVSDGVTKSPEKRSSLPRPSSILPPRRGVSG 1500 1510 1520 1530 1540 1550 210 220 230 240 250 260 pF1KB4 DRDENSFSLNSSISSSARRTTRSEPIRRAGKSGTSTPTTPGSTAITPGTPPSYSSRTPGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DRDENSFSLNSSISSSARRTTRSEPIRRAGKSGTSTPTTPGSTAITPGTPPSYSSRTPGT 1560 1570 1580 1590 1600 1610 270 280 290 300 310 320 pF1KB4 PGTPSYPRTPHTPGTPKSAILVPSEKKVAIIRTPPKSPATPKQLRLINQPLPDLKNVKSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PGTPSYPRTPHTPGTPKSAILVPSEKKVAIIRTPPKSPATPKQLRLINQPLPDLKNVKSK 1620 1630 1640 1650 1660 1670 330 340 350 360 370 380 pF1KB4 IGSTDNIKYQPKGGQVQIVTKKIDLSHVTSKCGSLKNIRHRPGGGRVKIESVKLDFKEKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IGSTDNIKYQPKGGQVQIVTKKIDLSHVTSKCGSLKNIRHRPGGGRVKIESVKLDFKEKA 1680 1690 1700 1710 1720 1730 390 400 410 420 430 440 pF1KB4 QAKVGSLDNAHHVPGGGNVKIDSQKLNFREHAKARVDHGAEIITQSPGRSSVASPRRLSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QAKVGSLDNAHHVPGGGNVKIDSQKLNFREHAKARVDHGAEIITQSPGRSSVASPRRLSN 1740 1750 1760 1770 1780 1790 450 460 470 pF1KB4 VSSSGSINLLESPQLATLAEDVTAALAKQGL ::::::::::::::::::::::::::::::: XP_016 VSSSGSINLLESPQLATLAEDVTAALAKQGL 1800 1810 1820 >-- initn: 1038 init1: 982 opt: 1003 Z-score: 546.4 bits: 112.4 E(85289): 1.1e-23 Smith-Waterman score: 1017; 56.7% identity (71.3% similar) in 335 aa overlap (1-316:1-331) 10 20 30 40 50 60 pF1KB4 MADERKDEAKAPHWTSAPLTEASAHSHPPEIKDQGGAGEGLVRSANGFPYREDEEGAFGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MADERKDEAKAPHWTSAPLTEASAHSHPPEIKDQGGAGEGLVRSANGFPYREDEEGAFGE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 HGSQGTYSNTKENGINGELTSADRETAEEVSARIVQVVTAEAVAVLKGEQEKEAQHKDQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HGSQGTYSNTKENGINGELTSADRETAEEVSARIVQVVTAEAVAVLKGEQEKEAQHKDQT 70 80 90 100 110 120 130 140 150 160 170 pF1KB4 AALPLAAEETANLPPSPPPSPASEQTVTVEE----AAGGE----SALAPSVFKQA--KDK ::::::::::::::::::::::::::::::: :. : . :.::. . . :.: XP_016 AALPLAAEETANLPPSPPPSPASEQTVTVEEDLLTASKMEFHDQQELTPSTAEPSDQKEK 130 140 150 160 170 180 180 190 200 210 220 pF1KB4 VSDGVTKSPE--KRSSL---PRPSSILPPRRGVSGDRDENS-FSL--NSSISSSARRTTR :. .: : :...: :. .. : .. ..: ..:.. ..: .. ..: . XP_016 ESEKQSKPGEDLKHAALVSQPETTKTYPDKKDMQGTEEEKAPLALFGHTLVASLEDMKQK 190 200 210 220 230 240 230 240 250 260 270 280 pF1KB4 SEP-IRRAGKSGTSTPTTPGSTAITPGTPPSYSSRTPGTPGTPSYPRTPHTPGTPKSAIL .:: . : . . : :: :. ... .: : : :: :... XP_016 TEPSLVVPGIDLPKEPPTPKEQKDWFIEMPTEAKKDEWGLVAPISP-GPLTPMREKDVFD 250 260 270 280 290 290 300 310 320 330 340 pF1KB4 VPSEKKVAIIRTPPKSPATPKQLRLINQPLPDLKNVKSKIGSTDNIKYQPKGGQVQIVTK . . . .: :: .. : :: .:: XP_016 DIPKWEGKQFDSPMPSPFQGGSFTL---PLDVMKNEIVTETSPFAPAFLQPDDKKSLQQT 300 310 320 330 340 350 350 360 370 380 390 400 pF1KB4 KIDLSHVTSKCGSLKNIRHRPGGGRVKIESVKLDFKEKAQAKVGSLDNAHHVPGGGNVKI XP_016 SGPATAKDSFKIEEPHEAKPDKMAEAPPSEAMTLPKDAHIPVVEEHVMGKVLEEEKEAIN 360 370 380 390 400 410 >>XP_016859618 (OMIM: 157130) PREDICTED: microtubule-ass (1820 aa) initn: 2065 init1: 2065 opt: 2075 Z-score: 1116.3 bits: 217.8 E(85289): 1.9e-55 Smith-Waterman score: 2075; 79.3% identity (87.9% similar) in 421 aa overlap (54-471:1405-1820) 30 40 50 60 70 80 pF1KB4 AHSHPPEIKDQGGAGEGLVRSANGFPYREDEEGAFGEHGSQGTYSNTKENGIN---GELT :: : : .. .. ::. .. :... XP_016 DSIMDADSLWVDTQDDDRSIMTEQLETIPKEEKAEKEARRSSLEKHRKEKPFKTGRGRIS 1380 1390 1400 1410 1420 1430 90 100 110 120 130 140 pF1KB4 SADRETAEEVSARIVQVVTAEAVAVLKGEQEKEAQHKDQTAALPLAAEETANLPPSPPPS . .:..:.. . . . . . . :.: :... . .. . . . : XP_016 TPERKVAKKEPSTVSRDEVRRKKVYKKAELAKKTEVQAHSPSRKFILK-----PAIKYTR 1440 1450 1460 1470 1480 150 160 170 180 190 200 pF1KB4 PASEQTVTVEEAAGGESALAPSVFKQAKDKVSDGVTKSPEKRSSLPRPSSILPPRRGVSG :. . : . .:::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PTHLSCVKRKTTAGGESALAPSVFKQAKDKVSDGVTKSPEKRSSLPRPSSILPPRRGVSG 1490 1500 1510 1520 1530 1540 210 220 230 240 250 260 pF1KB4 DRDENSFSLNSSISSSARRTTRSEPIRRAGKSGTSTPTTPGSTAITPGTPPSYSSRTPGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DRDENSFSLNSSISSSARRTTRSEPIRRAGKSGTSTPTTPGSTAITPGTPPSYSSRTPGT 1550 1560 1570 1580 1590 1600 270 280 290 300 310 320 pF1KB4 PGTPSYPRTPHTPGTPKSAILVPSEKKVAIIRTPPKSPATPKQLRLINQPLPDLKNVKSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PGTPSYPRTPHTPGTPKSAILVPSEKKVAIIRTPPKSPATPKQLRLINQPLPDLKNVKSK 1610 1620 1630 1640 1650 1660 330 340 350 360 370 380 pF1KB4 IGSTDNIKYQPKGGQVQIVTKKIDLSHVTSKCGSLKNIRHRPGGGRVKIESVKLDFKEKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IGSTDNIKYQPKGGQVQIVTKKIDLSHVTSKCGSLKNIRHRPGGGRVKIESVKLDFKEKA 1670 1680 1690 1700 1710 1720 390 400 410 420 430 440 pF1KB4 QAKVGSLDNAHHVPGGGNVKIDSQKLNFREHAKARVDHGAEIITQSPGRSSVASPRRLSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QAKVGSLDNAHHVPGGGNVKIDSQKLNFREHAKARVDHGAEIITQSPGRSSVASPRRLSN 1730 1740 1750 1760 1770 1780 450 460 470 pF1KB4 VSSSGSINLLESPQLATLAEDVTAALAKQGL ::::::::::::::::::::::::::::::: XP_016 VSSSGSINLLESPQLATLAEDVTAALAKQGL 1790 1800 1810 1820 >-- initn: 859 init1: 842 opt: 1018 Z-score: 554.4 bits: 113.9 E(85289): 3.8e-24 Smith-Waterman score: 1018; 57.1% identity (71.9% similar) in 331 aa overlap (1-316:1-326) 10 20 30 40 50 60 pF1KB4 MADERKDEAKAPHWTSAPLTEASAHSHPPEIKDQGGAGEGLVRSANGFPYREDEEGAFGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MADERKDEAKAPHWTSAPLTEASAHSHPPEIKDQGGAGEGLVRSANGFPYREDEEGAFGE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 HGSQGTYSNTKENGINGELTSADRETAEEVSARIVQVVTAEAVAVLKGEQEKEAQHKDQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HGSQGTYSNTKENGINGELTSADRETAEEVSARIVQVVTAEAVAVLKGEQEKEAQHKDQT 70 80 90 100 110 120 130 140 150 160 170 pF1KB4 AALPLAAEETANLPPSPPPSPASEQTVTVEEAAGGE----SALAPSVFKQA--KDKVSDG :::::: :::::::::::::::::::::::::. : . :.::. . . :.: :. XP_016 AALPLA-EETANLPPSPPPSPASEQTVTVEEASKMEFHDQQELTPSTAEPSDQKEKESEK 130 140 150 160 170 180 190 200 210 220 pF1KB4 VTKSPE--KRSSL---PRPSSILPPRRGVSGDRDENS-FSL--NSSISSSARRTTRSEP- .: : :...: :. .. : .. ..: ..:.. ..: .. ..: ..:: XP_016 QSKPGEDLKHAALVSQPETTKTYPDKKDMQGTEEEKAPLALFGHTLVASLEDMKQKTEPS 180 190 200 210 220 230 230 240 250 260 270 280 pF1KB4 IRRAGKSGTSTPTTPGSTAITPGTPPSYSSRTPGTPGTPSYPRTPHTPGTPKSAILVPSE . : . . : :: :. ... .: : : :: :... . XP_016 LVVPGIDLPKEPPTPKEQKDWFIEMPTEAKKDEWGLVAPISP-GPLTPMREKDVFDDIPK 240 250 260 270 280 290 290 300 310 320 330 340 pF1KB4 KKVAIIRTPPKSPATPKQLRLINQPLPDLKNVKSKIGSTDNIKYQPKGGQVQIVTKKIDL . . .: :: .. : :: .:: XP_016 WEGKQFDSPMPSPFQGGSFTL---PLDVMKNEIVTETSPFAPAFLQPDDKKSLQQTSGPA 300 310 320 330 340 350 350 360 370 380 390 400 pF1KB4 SHVTSKCGSLKNIRHRPGGGRVKIESVKLDFKEKAQAKVGSLDNAHHVPGGGNVKIDSQK XP_016 TAKDSFKIEEPHEAKPDKMAEAPPSEAMTLPKDAHIPVVEEHVMGKVLEEEKEAINQETV 360 370 380 390 400 410 >>XP_016859622 (OMIM: 157130) PREDICTED: microtubule-ass (1669 aa) initn: 2069 init1: 2069 opt: 2072 Z-score: 1115.3 bits: 217.5 E(85289): 2.2e-55 Smith-Waterman score: 2072; 80.1% identity (87.7% similar) in 422 aa overlap (54-471:1252-1669) 30 40 50 60 70 80 pF1KB4 AHSHPPEIKDQGGAGEGLVRSANGFPYREDEEGAFGEHGSQGTYSNTKENGIN---GELT :: : : .. .. ::. .. :... XP_016 DSIMDADSLWVDTQDDDRSIMTEQLETIPKEEKAEKEARRSSLEKHRKEKPFKTGRGRIS 1230 1240 1250 1260 1270 1280 90 100 110 120 130 140 pF1KB4 SADRETAEEVSARIVQVVTAEAVAVLKGEQEKEAQHKDQTAALPLAAEETANLPPSPPPS . .:..:.. . . . . . :: : . . :.. . : : ... : XP_016 TPERKVAKKEPSTVSRDEVRRKKAVYK--KAELAKKTEVQAHSP--SRKFILKPAIKYTR 1290 1300 1310 1320 1330 150 160 170 180 190 pF1KB4 PASEQTVTVEE-AAGGESALAPSVFKQAKDKVSDGVTKSPEKRSSLPRPSSILPPRRGVS :. . : . :::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PTHLSCVKRKTTAAGGESALAPSVFKQAKDKVSDGVTKSPEKRSSLPRPSSILPPRRGVS 1340 1350 1360 1370 1380 1390 200 210 220 230 240 250 pF1KB4 GDRDENSFSLNSSISSSARRTTRSEPIRRAGKSGTSTPTTPGSTAITPGTPPSYSSRTPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GDRDENSFSLNSSISSSARRTTRSEPIRRAGKSGTSTPTTPGSTAITPGTPPSYSSRTPG 1400 1410 1420 1430 1440 1450 260 270 280 290 300 310 pF1KB4 TPGTPSYPRTPHTPGTPKSAILVPSEKKVAIIRTPPKSPATPKQLRLINQPLPDLKNVKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TPGTPSYPRTPHTPGTPKSAILVPSEKKVAIIRTPPKSPATPKQLRLINQPLPDLKNVKS 1460 1470 1480 1490 1500 1510 320 330 340 350 360 370 pF1KB4 KIGSTDNIKYQPKGGQVQIVTKKIDLSHVTSKCGSLKNIRHRPGGGRVKIESVKLDFKEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KIGSTDNIKYQPKGGQVQIVTKKIDLSHVTSKCGSLKNIRHRPGGGRVKIESVKLDFKEK 1520 1530 1540 1550 1560 1570 380 390 400 410 420 430 pF1KB4 AQAKVGSLDNAHHVPGGGNVKIDSQKLNFREHAKARVDHGAEIITQSPGRSSVASPRRLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AQAKVGSLDNAHHVPGGGNVKIDSQKLNFREHAKARVDHGAEIITQSPGRSSVASPRRLS 1580 1590 1600 1610 1620 1630 440 450 460 470 pF1KB4 NVSSSGSINLLESPQLATLAEDVTAALAKQGL :::::::::::::::::::::::::::::::: XP_016 NVSSSGSINLLESPQLATLAEDVTAALAKQGL 1640 1650 1660 >>XP_016859624 (OMIM: 157130) PREDICTED: microtubule-ass (1669 aa) initn: 2069 init1: 2069 opt: 2072 Z-score: 1115.3 bits: 217.5 E(85289): 2.2e-55 Smith-Waterman score: 2072; 80.1% identity (87.7% similar) in 422 aa overlap (54-471:1252-1669) 30 40 50 60 70 80 pF1KB4 AHSHPPEIKDQGGAGEGLVRSANGFPYREDEEGAFGEHGSQGTYSNTKENGIN---GELT :: : : .. .. ::. .. :... XP_016 DSIMDADSLWVDTQDDDRSIMTEQLETIPKEEKAEKEARRSSLEKHRKEKPFKTGRGRIS 1230 1240 1250 1260 1270 1280 90 100 110 120 130 140 pF1KB4 SADRETAEEVSARIVQVVTAEAVAVLKGEQEKEAQHKDQTAALPLAAEETANLPPSPPPS . .:..:.. . . . . . :: : . . :.. . : : ... : XP_016 TPERKVAKKEPSTVSRDEVRRKKAVYK--KAELAKKTEVQAHSP--SRKFILKPAIKYTR 1290 1300 1310 1320 1330 150 160 170 180 190 pF1KB4 PASEQTVTVEE-AAGGESALAPSVFKQAKDKVSDGVTKSPEKRSSLPRPSSILPPRRGVS :. . : . :::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PTHLSCVKRKTTAAGGESALAPSVFKQAKDKVSDGVTKSPEKRSSLPRPSSILPPRRGVS 1340 1350 1360 1370 1380 1390 200 210 220 230 240 250 pF1KB4 GDRDENSFSLNSSISSSARRTTRSEPIRRAGKSGTSTPTTPGSTAITPGTPPSYSSRTPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GDRDENSFSLNSSISSSARRTTRSEPIRRAGKSGTSTPTTPGSTAITPGTPPSYSSRTPG 1400 1410 1420 1430 1440 1450 260 270 280 290 300 310 pF1KB4 TPGTPSYPRTPHTPGTPKSAILVPSEKKVAIIRTPPKSPATPKQLRLINQPLPDLKNVKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TPGTPSYPRTPHTPGTPKSAILVPSEKKVAIIRTPPKSPATPKQLRLINQPLPDLKNVKS 1460 1470 1480 1490 1500 1510 320 330 340 350 360 370 pF1KB4 KIGSTDNIKYQPKGGQVQIVTKKIDLSHVTSKCGSLKNIRHRPGGGRVKIESVKLDFKEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KIGSTDNIKYQPKGGQVQIVTKKIDLSHVTSKCGSLKNIRHRPGGGRVKIESVKLDFKEK 1520 1530 1540 1550 1560 1570 380 390 400 410 420 430 pF1KB4 AQAKVGSLDNAHHVPGGGNVKIDSQKLNFREHAKARVDHGAEIITQSPGRSSVASPRRLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AQAKVGSLDNAHHVPGGGNVKIDSQKLNFREHAKARVDHGAEIITQSPGRSSVASPRRLS 1580 1590 1600 1610 1620 1630 440 450 460 470 pF1KB4 NVSSSGSINLLESPQLATLAEDVTAALAKQGL :::::::::::::::::::::::::::::::: XP_016 NVSSSGSINLLESPQLATLAEDVTAALAKQGL 1640 1650 1660 >>XP_016859623 (OMIM: 157130) PREDICTED: microtubule-ass (1669 aa) initn: 2069 init1: 2069 opt: 2072 Z-score: 1115.3 bits: 217.5 E(85289): 2.2e-55 Smith-Waterman score: 2072; 80.1% identity (87.7% similar) in 422 aa overlap (54-471:1252-1669) 30 40 50 60 70 80 pF1KB4 AHSHPPEIKDQGGAGEGLVRSANGFPYREDEEGAFGEHGSQGTYSNTKENGIN---GELT :: : : .. .. ::. .. :... XP_016 DSIMDADSLWVDTQDDDRSIMTEQLETIPKEEKAEKEARRSSLEKHRKEKPFKTGRGRIS 1230 1240 1250 1260 1270 1280 90 100 110 120 130 140 pF1KB4 SADRETAEEVSARIVQVVTAEAVAVLKGEQEKEAQHKDQTAALPLAAEETANLPPSPPPS . .:..:.. . . . . . :: : . . :.. . : : ... : XP_016 TPERKVAKKEPSTVSRDEVRRKKAVYK--KAELAKKTEVQAHSP--SRKFILKPAIKYTR 1290 1300 1310 1320 1330 150 160 170 180 190 pF1KB4 PASEQTVTVEE-AAGGESALAPSVFKQAKDKVSDGVTKSPEKRSSLPRPSSILPPRRGVS :. . : . :::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PTHLSCVKRKTTAAGGESALAPSVFKQAKDKVSDGVTKSPEKRSSLPRPSSILPPRRGVS 1340 1350 1360 1370 1380 1390 200 210 220 230 240 250 pF1KB4 GDRDENSFSLNSSISSSARRTTRSEPIRRAGKSGTSTPTTPGSTAITPGTPPSYSSRTPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GDRDENSFSLNSSISSSARRTTRSEPIRRAGKSGTSTPTTPGSTAITPGTPPSYSSRTPG 1400 1410 1420 1430 1440 1450 260 270 280 290 300 310 pF1KB4 TPGTPSYPRTPHTPGTPKSAILVPSEKKVAIIRTPPKSPATPKQLRLINQPLPDLKNVKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TPGTPSYPRTPHTPGTPKSAILVPSEKKVAIIRTPPKSPATPKQLRLINQPLPDLKNVKS 1460 1470 1480 1490 1500 1510 320 330 340 350 360 370 pF1KB4 KIGSTDNIKYQPKGGQVQIVTKKIDLSHVTSKCGSLKNIRHRPGGGRVKIESVKLDFKEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KIGSTDNIKYQPKGGQVQIVTKKIDLSHVTSKCGSLKNIRHRPGGGRVKIESVKLDFKEK 1520 1530 1540 1550 1560 1570 380 390 400 410 420 430 pF1KB4 AQAKVGSLDNAHHVPGGGNVKIDSQKLNFREHAKARVDHGAEIITQSPGRSSVASPRRLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AQAKVGSLDNAHHVPGGGNVKIDSQKLNFREHAKARVDHGAEIITQSPGRSSVASPRRLS 1580 1590 1600 1610 1620 1630 440 450 460 470 pF1KB4 NVSSSGSINLLESPQLATLAEDVTAALAKQGL :::::::::::::::::::::::::::::::: XP_016 NVSSSGSINLLESPQLATLAEDVTAALAKQGL 1640 1650 1660 471 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 05:44:07 2016 done: Sat Nov 5 05:44:09 2016 Total Scan time: 12.370 Total Display time: 0.100 Function used was FASTA [36.3.4 Apr, 2011]