FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB4249, 362 aa 1>>>pF1KB4249 362 - 362 aa - 362 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.4286+/-0.000544; mu= 15.7271+/- 0.034 mean_var=124.0237+/-33.542, 0's: 0 Z-trim(107.6): 623 B-trim: 923 in 1/52 Lambda= 0.115165 statistics sampled from 14893 (15649) to 14893 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.503), E-opt: 0.2 (0.183), width: 16 Scan time: 7.330 The best scores are: opt bits E(85289) NP_064707 (OMIM: 610376) atypical chemokine recept ( 362) 2422 414.8 1.6e-115 XP_016860005 (OMIM: 610376) PREDICTED: atypical ch ( 362) 2422 414.8 1.6e-115 XP_005246155 (OMIM: 610376) PREDICTED: atypical ch ( 362) 2422 414.8 1.6e-115 XP_005246154 (OMIM: 610376) PREDICTED: atypical ch ( 362) 2422 414.8 1.6e-115 NP_009195 (OMIM: 605307) G-protein coupled recepto ( 404) 695 127.9 4e-29 XP_011536127 (OMIM: 605307) PREDICTED: G-protein c ( 404) 695 127.9 4e-29 XP_011536126 (OMIM: 605307) PREDICTED: G-protein c ( 404) 695 127.9 4e-29 XP_011536129 (OMIM: 605307) PREDICTED: G-protein c ( 404) 695 127.9 4e-29 NP_033611 (OMIM: 106165,145500,267430) type-1 angi ( 359) 624 116.0 1.3e-25 NP_000676 (OMIM: 106165,145500,267430) type-1 angi ( 359) 624 116.0 1.3e-25 NP_114438 (OMIM: 106165,145500,267430) type-1 angi ( 388) 624 116.1 1.4e-25 NP_114038 (OMIM: 106165,145500,267430) type-1 angi ( 394) 624 116.1 1.4e-25 NP_004826 (OMIM: 106165,145500,267430) type-1 angi ( 394) 624 116.1 1.4e-25 XP_005246587 (OMIM: 146928) PREDICTED: C-X-C chemo ( 360) 618 115.0 2.6e-25 NP_001161770 (OMIM: 146928) C-X-C chemokine recept ( 360) 618 115.0 2.6e-25 XP_016859481 (OMIM: 146928) PREDICTED: C-X-C chemo ( 360) 618 115.0 2.6e-25 XP_016859480 (OMIM: 146928) PREDICTED: C-X-C chemo ( 360) 618 115.0 2.6e-25 XP_016859479 (OMIM: 146928) PREDICTED: C-X-C chemo ( 360) 618 115.0 2.6e-25 NP_001548 (OMIM: 146928) C-X-C chemokine receptor ( 360) 618 115.0 2.6e-25 NP_000625 (OMIM: 146929,609423) C-X-C chemokine re ( 350) 612 114.0 5.1e-25 NP_003458 (OMIM: 162643,193670) C-X-C chemokine re ( 352) 608 113.4 8.2e-25 NP_001008540 (OMIM: 162643,193670) C-X-C chemokine ( 356) 608 113.4 8.2e-25 NP_001288646 (OMIM: 600242) C-C chemokine receptor ( 372) 573 107.6 4.8e-23 NP_001288647 (OMIM: 600242) C-C chemokine receptor ( 372) 573 107.6 4.8e-23 NP_001288645 (OMIM: 600242) C-C chemokine receptor ( 372) 573 107.6 4.8e-23 NP_001829 (OMIM: 600242) C-C chemokine receptor ty ( 378) 573 107.6 4.8e-23 NP_001286 (OMIM: 601159) C-C chemokine receptor ty ( 355) 570 107.0 6.5e-23 XP_016861176 (OMIM: 604836) PREDICTED: C-C chemoki ( 360) 567 106.6 9.3e-23 NP_005499 (OMIM: 604836) C-C chemokine receptor ty ( 360) 567 106.6 9.3e-23 NP_001288643 (OMIM: 600242) C-C chemokine receptor ( 315) 562 105.7 1.5e-22 NP_001495 (OMIM: 300574) C-X-C chemokine receptor ( 368) 560 105.4 2.1e-22 XP_005262313 (OMIM: 300574) PREDICTED: C-X-C chemo ( 378) 560 105.4 2.2e-22 NP_001136269 (OMIM: 300574) C-X-C chemokine recept ( 415) 560 105.5 2.3e-22 XP_016884924 (OMIM: 300574) PREDICTED: C-X-C chemo ( 415) 560 105.5 2.3e-22 NP_001164645 (OMIM: 601470,607339,609423,613784) C ( 387) 559 105.3 2.5e-22 XP_011535835 (OMIM: 300034) PREDICTED: type-2 angi ( 363) 558 105.1 2.6e-22 NP_000677 (OMIM: 300034) type-2 angiotensin II rec ( 363) 558 105.1 2.6e-22 NP_001093638 (OMIM: 601373,609532,610379,612522) C ( 352) 556 104.7 3.3e-22 NP_000570 (OMIM: 601373,609532,610379,612522) C-C ( 352) 556 104.7 3.3e-22 NP_001164643 (OMIM: 601470,607339,609423,613784) C ( 355) 556 104.7 3.3e-22 NP_001328 (OMIM: 601470,607339,609423,613784) CX3C ( 355) 556 104.7 3.3e-22 NP_001164642 (OMIM: 601470,607339,609423,613784) C ( 355) 556 104.7 3.3e-22 NP_001040 (OMIM: 182451) somatostatin receptor typ ( 391) 554 104.4 4.4e-22 NP_005192 (OMIM: 601834) C-C chemokine receptor ty ( 355) 549 103.6 7.3e-22 NP_001155970 (OMIM: 278150,609239) lysophosphatidi ( 344) 546 103.0 1e-21 NP_005758 (OMIM: 278150,609239) lysophosphatidic a ( 344) 546 103.0 1e-21 NP_001155969 (OMIM: 278150,609239) lysophosphatidi ( 344) 546 103.0 1e-21 XP_011532371 (OMIM: 601267) PREDICTED: C-C chemoki ( 360) 542 102.4 1.7e-21 NP_001116868 (OMIM: 601267) C-C chemokine receptor ( 360) 542 102.4 1.7e-21 NP_005273 (OMIM: 600551) G-protein coupled recepto ( 362) 540 102.1 2.1e-21 >>NP_064707 (OMIM: 610376) atypical chemokine receptor 3 (362 aa) initn: 2422 init1: 2422 opt: 2422 Z-score: 2195.2 bits: 414.8 E(85289): 1.6e-115 Smith-Waterman score: 2422; 100.0% identity (100.0% similar) in 362 aa overlap (1-362:1-362) 10 20 30 40 50 60 pF1KB4 MDLHLFDYSEPGNFSDISWPCNSSDCIVVDTVMCPNMPNKSVLLYTLSFIYIFIFVIGMI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_064 MDLHLFDYSEPGNFSDISWPCNSSDCIVVDTVMCPNMPNKSVLLYTLSFIYIFIFVIGMI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 ANSVVVWVNIQAKTTGYDTHCYILNLAIADLWVVLTIPVWVVSLVQHNQWPMGELTCKVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_064 ANSVVVWVNIQAKTTGYDTHCYILNLAIADLWVVLTIPVWVVSLVQHNQWPMGELTCKVT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 HLIFSINLFGSIFFLTCMSVDRYLSITYFTNTPSSRKKMVRRVVCILVWLLAFCVSLPDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_064 HLIFSINLFGSIFFLTCMSVDRYLSITYFTNTPSSRKKMVRRVVCILVWLLAFCVSLPDT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 YYLKTVTSASNNETYCRSFYPEHSIKEWLIGMELVSVVLGFAVPFSIIAVFYFLLARAIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_064 YYLKTVTSASNNETYCRSFYPEHSIKEWLIGMELVSVVLGFAVPFSIIAVFYFLLARAIS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 ASSDQEKHSSRKIIFSYVVVFLVCWLPYHVAVLLDIFSILHYIPFTCRLEHALFTALHVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_064 ASSDQEKHSSRKIIFSYVVVFLVCWLPYHVAVLLDIFSILHYIPFTCRLEHALFTALHVT 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 QCLSLVHCCVNPVLYSFINRNYRYELMKAFIFKYSAKTGLTKLIDASRVSETEYSALEQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_064 QCLSLVHCCVNPVLYSFINRNYRYELMKAFIFKYSAKTGLTKLIDASRVSETEYSALEQS 310 320 330 340 350 360 pF1KB4 TK :: NP_064 TK >>XP_016860005 (OMIM: 610376) PREDICTED: atypical chemok (362 aa) initn: 2422 init1: 2422 opt: 2422 Z-score: 2195.2 bits: 414.8 E(85289): 1.6e-115 Smith-Waterman score: 2422; 100.0% identity (100.0% similar) in 362 aa overlap (1-362:1-362) 10 20 30 40 50 60 pF1KB4 MDLHLFDYSEPGNFSDISWPCNSSDCIVVDTVMCPNMPNKSVLLYTLSFIYIFIFVIGMI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MDLHLFDYSEPGNFSDISWPCNSSDCIVVDTVMCPNMPNKSVLLYTLSFIYIFIFVIGMI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 ANSVVVWVNIQAKTTGYDTHCYILNLAIADLWVVLTIPVWVVSLVQHNQWPMGELTCKVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ANSVVVWVNIQAKTTGYDTHCYILNLAIADLWVVLTIPVWVVSLVQHNQWPMGELTCKVT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 HLIFSINLFGSIFFLTCMSVDRYLSITYFTNTPSSRKKMVRRVVCILVWLLAFCVSLPDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HLIFSINLFGSIFFLTCMSVDRYLSITYFTNTPSSRKKMVRRVVCILVWLLAFCVSLPDT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 YYLKTVTSASNNETYCRSFYPEHSIKEWLIGMELVSVVLGFAVPFSIIAVFYFLLARAIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YYLKTVTSASNNETYCRSFYPEHSIKEWLIGMELVSVVLGFAVPFSIIAVFYFLLARAIS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 ASSDQEKHSSRKIIFSYVVVFLVCWLPYHVAVLLDIFSILHYIPFTCRLEHALFTALHVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ASSDQEKHSSRKIIFSYVVVFLVCWLPYHVAVLLDIFSILHYIPFTCRLEHALFTALHVT 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 QCLSLVHCCVNPVLYSFINRNYRYELMKAFIFKYSAKTGLTKLIDASRVSETEYSALEQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QCLSLVHCCVNPVLYSFINRNYRYELMKAFIFKYSAKTGLTKLIDASRVSETEYSALEQS 310 320 330 340 350 360 pF1KB4 TK :: XP_016 TK >>XP_005246155 (OMIM: 610376) PREDICTED: atypical chemok (362 aa) initn: 2422 init1: 2422 opt: 2422 Z-score: 2195.2 bits: 414.8 E(85289): 1.6e-115 Smith-Waterman score: 2422; 100.0% identity (100.0% similar) in 362 aa overlap (1-362:1-362) 10 20 30 40 50 60 pF1KB4 MDLHLFDYSEPGNFSDISWPCNSSDCIVVDTVMCPNMPNKSVLLYTLSFIYIFIFVIGMI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MDLHLFDYSEPGNFSDISWPCNSSDCIVVDTVMCPNMPNKSVLLYTLSFIYIFIFVIGMI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 ANSVVVWVNIQAKTTGYDTHCYILNLAIADLWVVLTIPVWVVSLVQHNQWPMGELTCKVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ANSVVVWVNIQAKTTGYDTHCYILNLAIADLWVVLTIPVWVVSLVQHNQWPMGELTCKVT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 HLIFSINLFGSIFFLTCMSVDRYLSITYFTNTPSSRKKMVRRVVCILVWLLAFCVSLPDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HLIFSINLFGSIFFLTCMSVDRYLSITYFTNTPSSRKKMVRRVVCILVWLLAFCVSLPDT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 YYLKTVTSASNNETYCRSFYPEHSIKEWLIGMELVSVVLGFAVPFSIIAVFYFLLARAIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YYLKTVTSASNNETYCRSFYPEHSIKEWLIGMELVSVVLGFAVPFSIIAVFYFLLARAIS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 ASSDQEKHSSRKIIFSYVVVFLVCWLPYHVAVLLDIFSILHYIPFTCRLEHALFTALHVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ASSDQEKHSSRKIIFSYVVVFLVCWLPYHVAVLLDIFSILHYIPFTCRLEHALFTALHVT 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 QCLSLVHCCVNPVLYSFINRNYRYELMKAFIFKYSAKTGLTKLIDASRVSETEYSALEQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QCLSLVHCCVNPVLYSFINRNYRYELMKAFIFKYSAKTGLTKLIDASRVSETEYSALEQS 310 320 330 340 350 360 pF1KB4 TK :: XP_005 TK >>XP_005246154 (OMIM: 610376) PREDICTED: atypical chemok (362 aa) initn: 2422 init1: 2422 opt: 2422 Z-score: 2195.2 bits: 414.8 E(85289): 1.6e-115 Smith-Waterman score: 2422; 100.0% identity (100.0% similar) in 362 aa overlap (1-362:1-362) 10 20 30 40 50 60 pF1KB4 MDLHLFDYSEPGNFSDISWPCNSSDCIVVDTVMCPNMPNKSVLLYTLSFIYIFIFVIGMI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MDLHLFDYSEPGNFSDISWPCNSSDCIVVDTVMCPNMPNKSVLLYTLSFIYIFIFVIGMI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 ANSVVVWVNIQAKTTGYDTHCYILNLAIADLWVVLTIPVWVVSLVQHNQWPMGELTCKVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ANSVVVWVNIQAKTTGYDTHCYILNLAIADLWVVLTIPVWVVSLVQHNQWPMGELTCKVT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 HLIFSINLFGSIFFLTCMSVDRYLSITYFTNTPSSRKKMVRRVVCILVWLLAFCVSLPDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HLIFSINLFGSIFFLTCMSVDRYLSITYFTNTPSSRKKMVRRVVCILVWLLAFCVSLPDT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 YYLKTVTSASNNETYCRSFYPEHSIKEWLIGMELVSVVLGFAVPFSIIAVFYFLLARAIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YYLKTVTSASNNETYCRSFYPEHSIKEWLIGMELVSVVLGFAVPFSIIAVFYFLLARAIS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 ASSDQEKHSSRKIIFSYVVVFLVCWLPYHVAVLLDIFSILHYIPFTCRLEHALFTALHVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ASSDQEKHSSRKIIFSYVVVFLVCWLPYHVAVLLDIFSILHYIPFTCRLEHALFTALHVT 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 QCLSLVHCCVNPVLYSFINRNYRYELMKAFIFKYSAKTGLTKLIDASRVSETEYSALEQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QCLSLVHCCVNPVLYSFINRNYRYELMKAFIFKYSAKTGLTKLIDASRVSETEYSALEQS 310 320 330 340 350 360 pF1KB4 TK :: XP_005 TK >>NP_009195 (OMIM: 605307) G-protein coupled receptor 18 (404 aa) initn: 636 init1: 362 opt: 695 Z-score: 643.9 bits: 127.9 E(85289): 4e-29 Smith-Waterman score: 695; 34.2% identity (68.8% similar) in 292 aa overlap (40-331:52-336) 10 20 30 40 50 60 pF1KB4 EPGNFSDISWPCNSSDCIVVDTVMCPNMPNKSVLLYTLSFIYIFIFVIGMIANSVVVWVN : :.:..: :. .::.:.. : .:. :: NP_009 DLGEIHNWTELLDLFNHTLSECHVELSQSTKRVVLFAL---YLAMFVVGLVENLLVICVN 30 40 50 60 70 70 80 90 100 110 120 pF1KB4 IQAKTTGYDTHCYILNLAIADLWVVLTIPVWVVSLVQHNQWPMGELTCKVTHLIFSINLF ... . . ::::.::::: .::..:::.. .. : : ..:. :: .. .:.. NP_009 WRGSGRAGLMNLYILNMAIADLGIVLSLPVWMLEVTLDYTWLWGSFSCRFTHYFYFVNMY 80 90 100 110 120 130 130 140 150 160 170 180 pF1KB4 GSIFFLTCMSVDRYLSITYFTNTPSSRKKMVRRVVCILVWLLAFCVSLPDTYYLKTVTSA .:::::.:.:::::...: . . . .. :::..: .:.:. . ::.. ... : . NP_009 SSIFFLVCLSVDRYVTLTSASPSWQRYQHRVRRAMCAGIWVLSAIIPLPEVVHIQLVEGP 140 150 160 170 180 190 190 200 210 220 230 240 pF1KB4 SNNETYCRSFYPEHSIKEWLIGMELVSVVLGFAVPFSIIAVFYFLLARAISASSDQEKHS : .: . : .. . : ... : ...::: .:: .:.:: : : . .. ... NP_009 ---EPMCLFMAPFETYSTWALAVALSTTILGFLLPFPLITVFNVLTACRLRQPGQPKSRR 200 210 220 230 240 250 250 260 270 280 290 300 pF1KB4 SRKIIFSYVVVFLVCWLPYHVAVLLDIFSILHYIPFTCRLEHALFTALHVTQCLSLVHCC .. .::.::..:::::::..:: . : : . :.: : :. : .:.:..:: NP_009 HCLLLCAYVAVFVMCWLPYHVTLLLLTLHGTH-ISLHCHLVHLLYFFYDVIDCFSMLHCV 260 270 280 290 300 310 310 320 330 340 350 360 pF1KB4 VNPVLYSFINRNYRYELMKAFIFKYSAKTGLTKLIDASRVSETEYSALEQSTK .::.::.:.. ..: .:..: . NP_009 INPILYNFLSPHFRGRLLNAVVHYLPKDQTKAGTCASSSSCSTQHSIIITKGDSQPAAAA 320 330 340 350 360 370 >>XP_011536127 (OMIM: 605307) PREDICTED: G-protein coupl (404 aa) initn: 636 init1: 362 opt: 695 Z-score: 643.9 bits: 127.9 E(85289): 4e-29 Smith-Waterman score: 695; 34.2% identity (68.8% similar) in 292 aa overlap (40-331:52-336) 10 20 30 40 50 60 pF1KB4 EPGNFSDISWPCNSSDCIVVDTVMCPNMPNKSVLLYTLSFIYIFIFVIGMIANSVVVWVN : :.:..: :. .::.:.. : .:. :: XP_011 DLGEIHNWTELLDLFNHTLSECHVELSQSTKRVVLFAL---YLAMFVVGLVENLLVICVN 30 40 50 60 70 70 80 90 100 110 120 pF1KB4 IQAKTTGYDTHCYILNLAIADLWVVLTIPVWVVSLVQHNQWPMGELTCKVTHLIFSINLF ... . . ::::.::::: .::..:::.. .. : : ..:. :: .. .:.. XP_011 WRGSGRAGLMNLYILNMAIADLGIVLSLPVWMLEVTLDYTWLWGSFSCRFTHYFYFVNMY 80 90 100 110 120 130 130 140 150 160 170 180 pF1KB4 GSIFFLTCMSVDRYLSITYFTNTPSSRKKMVRRVVCILVWLLAFCVSLPDTYYLKTVTSA .:::::.:.:::::...: . . . .. :::..: .:.:. . ::.. ... : . XP_011 SSIFFLVCLSVDRYVTLTSASPSWQRYQHRVRRAMCAGIWVLSAIIPLPEVVHIQLVEGP 140 150 160 170 180 190 190 200 210 220 230 240 pF1KB4 SNNETYCRSFYPEHSIKEWLIGMELVSVVLGFAVPFSIIAVFYFLLARAISASSDQEKHS : .: . : .. . : ... : ...::: .:: .:.:: : : . .. ... XP_011 ---EPMCLFMAPFETYSTWALAVALSTTILGFLLPFPLITVFNVLTACRLRQPGQPKSRR 200 210 220 230 240 250 250 260 270 280 290 300 pF1KB4 SRKIIFSYVVVFLVCWLPYHVAVLLDIFSILHYIPFTCRLEHALFTALHVTQCLSLVHCC .. .::.::..:::::::..:: . : : . :.: : :. : .:.:..:: XP_011 HCLLLCAYVAVFVMCWLPYHVTLLLLTLHGTH-ISLHCHLVHLLYFFYDVIDCFSMLHCV 260 270 280 290 300 310 310 320 330 340 350 360 pF1KB4 VNPVLYSFINRNYRYELMKAFIFKYSAKTGLTKLIDASRVSETEYSALEQSTK .::.::.:.. ..: .:..: . XP_011 INPILYNFLSPHFRGRLLNAVVHYLPKDQTKAGTCASSSSCSTQHSIIITKGDSQPAAAA 320 330 340 350 360 370 >>XP_011536126 (OMIM: 605307) PREDICTED: G-protein coupl (404 aa) initn: 636 init1: 362 opt: 695 Z-score: 643.9 bits: 127.9 E(85289): 4e-29 Smith-Waterman score: 695; 34.2% identity (68.8% similar) in 292 aa overlap (40-331:52-336) 10 20 30 40 50 60 pF1KB4 EPGNFSDISWPCNSSDCIVVDTVMCPNMPNKSVLLYTLSFIYIFIFVIGMIANSVVVWVN : :.:..: :. .::.:.. : .:. :: XP_011 DLGEIHNWTELLDLFNHTLSECHVELSQSTKRVVLFAL---YLAMFVVGLVENLLVICVN 30 40 50 60 70 70 80 90 100 110 120 pF1KB4 IQAKTTGYDTHCYILNLAIADLWVVLTIPVWVVSLVQHNQWPMGELTCKVTHLIFSINLF ... . . ::::.::::: .::..:::.. .. : : ..:. :: .. .:.. XP_011 WRGSGRAGLMNLYILNMAIADLGIVLSLPVWMLEVTLDYTWLWGSFSCRFTHYFYFVNMY 80 90 100 110 120 130 130 140 150 160 170 180 pF1KB4 GSIFFLTCMSVDRYLSITYFTNTPSSRKKMVRRVVCILVWLLAFCVSLPDTYYLKTVTSA .:::::.:.:::::...: . . . .. :::..: .:.:. . ::.. ... : . XP_011 SSIFFLVCLSVDRYVTLTSASPSWQRYQHRVRRAMCAGIWVLSAIIPLPEVVHIQLVEGP 140 150 160 170 180 190 190 200 210 220 230 240 pF1KB4 SNNETYCRSFYPEHSIKEWLIGMELVSVVLGFAVPFSIIAVFYFLLARAISASSDQEKHS : .: . : .. . : ... : ...::: .:: .:.:: : : . .. ... XP_011 ---EPMCLFMAPFETYSTWALAVALSTTILGFLLPFPLITVFNVLTACRLRQPGQPKSRR 200 210 220 230 240 250 250 260 270 280 290 300 pF1KB4 SRKIIFSYVVVFLVCWLPYHVAVLLDIFSILHYIPFTCRLEHALFTALHVTQCLSLVHCC .. .::.::..:::::::..:: . : : . :.: : :. : .:.:..:: XP_011 HCLLLCAYVAVFVMCWLPYHVTLLLLTLHGTH-ISLHCHLVHLLYFFYDVIDCFSMLHCV 260 270 280 290 300 310 310 320 330 340 350 360 pF1KB4 VNPVLYSFINRNYRYELMKAFIFKYSAKTGLTKLIDASRVSETEYSALEQSTK .::.::.:.. ..: .:..: . XP_011 INPILYNFLSPHFRGRLLNAVVHYLPKDQTKAGTCASSSSCSTQHSIIITKGDSQPAAAA 320 330 340 350 360 370 >>XP_011536129 (OMIM: 605307) PREDICTED: G-protein coupl (404 aa) initn: 636 init1: 362 opt: 695 Z-score: 643.9 bits: 127.9 E(85289): 4e-29 Smith-Waterman score: 695; 34.2% identity (68.8% similar) in 292 aa overlap (40-331:52-336) 10 20 30 40 50 60 pF1KB4 EPGNFSDISWPCNSSDCIVVDTVMCPNMPNKSVLLYTLSFIYIFIFVIGMIANSVVVWVN : :.:..: :. .::.:.. : .:. :: XP_011 DLGEIHNWTELLDLFNHTLSECHVELSQSTKRVVLFAL---YLAMFVVGLVENLLVICVN 30 40 50 60 70 70 80 90 100 110 120 pF1KB4 IQAKTTGYDTHCYILNLAIADLWVVLTIPVWVVSLVQHNQWPMGELTCKVTHLIFSINLF ... . . ::::.::::: .::..:::.. .. : : ..:. :: .. .:.. XP_011 WRGSGRAGLMNLYILNMAIADLGIVLSLPVWMLEVTLDYTWLWGSFSCRFTHYFYFVNMY 80 90 100 110 120 130 130 140 150 160 170 180 pF1KB4 GSIFFLTCMSVDRYLSITYFTNTPSSRKKMVRRVVCILVWLLAFCVSLPDTYYLKTVTSA .:::::.:.:::::...: . . . .. :::..: .:.:. . ::.. ... : . XP_011 SSIFFLVCLSVDRYVTLTSASPSWQRYQHRVRRAMCAGIWVLSAIIPLPEVVHIQLVEGP 140 150 160 170 180 190 190 200 210 220 230 240 pF1KB4 SNNETYCRSFYPEHSIKEWLIGMELVSVVLGFAVPFSIIAVFYFLLARAISASSDQEKHS : .: . : .. . : ... : ...::: .:: .:.:: : : . .. ... XP_011 ---EPMCLFMAPFETYSTWALAVALSTTILGFLLPFPLITVFNVLTACRLRQPGQPKSRR 200 210 220 230 240 250 250 260 270 280 290 300 pF1KB4 SRKIIFSYVVVFLVCWLPYHVAVLLDIFSILHYIPFTCRLEHALFTALHVTQCLSLVHCC .. .::.::..:::::::..:: . : : . :.: : :. : .:.:..:: XP_011 HCLLLCAYVAVFVMCWLPYHVTLLLLTLHGTH-ISLHCHLVHLLYFFYDVIDCFSMLHCV 260 270 280 290 300 310 310 320 330 340 350 360 pF1KB4 VNPVLYSFINRNYRYELMKAFIFKYSAKTGLTKLIDASRVSETEYSALEQSTK .::.::.:.. ..: .:..: . XP_011 INPILYNFLSPHFRGRLLNAVVHYLPKDQTKAGTCASSSSCSTQHSIIITKGDSQPAAAA 320 330 340 350 360 370 >>NP_033611 (OMIM: 106165,145500,267430) type-1 angioten (359 aa) initn: 528 init1: 385 opt: 624 Z-score: 580.7 bits: 116.0 E(85289): 1.3e-25 Smith-Waterman score: 624; 31.8% identity (66.2% similar) in 340 aa overlap (34-362:18-350) 10 20 30 40 50 60 pF1KB4 HLFDYSEPGNFSDISWPCNSSDCIVVDTVMCPNMPNKSVLLYTLSFIYIFIFVIGMIANS ::. .. .. . .: .:::.:...:: NP_033 MILNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNS 10 20 30 40 70 80 90 100 110 120 pF1KB4 ---VVVWVNIQAKTTGYDTHCYILNLAIADLWVVLTIPVWVVSLVQHNQWPMGELTCKVT .:.. .. ::.. ..::::.::: .::.:.:.: ... .::.:. ::.. NP_033 LVVIVIYFYMKLKTVA---SVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIA 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB4 HLIFSINLFGSIFFLTCMSVDRYLSITYFTNTPSSRKKMVRRVVCILVWLLAFCVSLPDT :.::..:.:.:::.:.::::.:.. .. : .: .:.::..:::: .::: NP_033 SASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAI 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB4 YYLKTVTSASNNETYCRSFYPEHSIKEWLIGMELVSVVLGFAVPFSIIAVFYFLLARAIS . .. ..: : : .:. : . . ::. :.. .::: :: :: . : :. .:.. NP_033 IHRNVFFIENTNITVC-AFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALK 170 180 190 200 210 220 250 260 270 280 290 pF1KB4 ASSDQEKHSSR-----KIIFSYVVVFLVCWLPYHVAVLLDIFSILHYIPFTCRLEHALFT . . .:.. : :::.. :. :. :.:... ..::.. : : ::. . : NP_033 KAYEIQKNKPRNDDIFKIIMAIVLFFFFSWIPHQIFTFLDVLIQLGIIR-DCRIADIVDT 230 240 250 260 270 280 300 310 320 330 340 350 pF1KB4 ALHVTQCLSLVHCCVNPVLYSFINRNY-RY--ELMKAFIFKYSAKTGLTKLIDASRVSET :. .: :.. . :.::..:.:..... :: .:.: . : .....:. . : .: NP_033 AMPITICIAYFNNCLNPLFYGFLGKKFKRYFLQLLKYIPPKAKSHSNLSTKM--STLSYR 290 300 310 320 330 340 360 pF1KB4 EYSALEQSTK . . .::: NP_033 PSDNVSSSTKKPAPCFEVE 350 >>NP_000676 (OMIM: 106165,145500,267430) type-1 angioten (359 aa) initn: 528 init1: 385 opt: 624 Z-score: 580.7 bits: 116.0 E(85289): 1.3e-25 Smith-Waterman score: 624; 31.8% identity (66.2% similar) in 340 aa overlap (34-362:18-350) 10 20 30 40 50 60 pF1KB4 HLFDYSEPGNFSDISWPCNSSDCIVVDTVMCPNMPNKSVLLYTLSFIYIFIFVIGMIANS ::. .. .. . .: .:::.:...:: NP_000 MILNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNS 10 20 30 40 70 80 90 100 110 120 pF1KB4 ---VVVWVNIQAKTTGYDTHCYILNLAIADLWVVLTIPVWVVSLVQHNQWPMGELTCKVT .:.. .. ::.. ..::::.::: .::.:.:.: ... .::.:. ::.. NP_000 LVVIVIYFYMKLKTVA---SVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIA 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB4 HLIFSINLFGSIFFLTCMSVDRYLSITYFTNTPSSRKKMVRRVVCILVWLLAFCVSLPDT :.::..:.:.:::.:.::::.:.. .. : .: .:.::..:::: .::: NP_000 SASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAI 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB4 YYLKTVTSASNNETYCRSFYPEHSIKEWLIGMELVSVVLGFAVPFSIIAVFYFLLARAIS . .. ..: : : .:. : . . ::. :.. .::: :: :: . : :. .:.. NP_000 IHRNVFFIENTNITVC-AFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALK 170 180 190 200 210 220 250 260 270 280 290 pF1KB4 ASSDQEKHSSR-----KIIFSYVVVFLVCWLPYHVAVLLDIFSILHYIPFTCRLEHALFT . . .:.. : :::.. :. :. :.:... ..::.. : : ::. . : NP_000 KAYEIQKNKPRNDDIFKIIMAIVLFFFFSWIPHQIFTFLDVLIQLGIIR-DCRIADIVDT 230 240 250 260 270 280 300 310 320 330 340 350 pF1KB4 ALHVTQCLSLVHCCVNPVLYSFINRNY-RY--ELMKAFIFKYSAKTGLTKLIDASRVSET :. .: :.. . :.::..:.:..... :: .:.: . : .....:. . : .: NP_000 AMPITICIAYFNNCLNPLFYGFLGKKFKRYFLQLLKYIPPKAKSHSNLSTKM--STLSYR 290 300 310 320 330 340 360 pF1KB4 EYSALEQSTK . . .::: NP_000 PSDNVSSSTKKPAPCFEVE 350 362 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 21:31:43 2016 done: Thu Nov 3 21:31:44 2016 Total Scan time: 7.330 Total Display time: 0.040 Function used was FASTA [36.3.4 Apr, 2011]