FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB4270, 419 aa 1>>>pF1KB4270 419 - 419 aa - 419 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.9476+/-0.000444; mu= 20.3175+/- 0.028 mean_var=105.2743+/-25.771, 0's: 0 Z-trim(111.8): 598 B-trim: 1191 in 1/50 Lambda= 0.125001 statistics sampled from 19748 (20483) to 19748 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.585), E-opt: 0.2 (0.24), width: 16 Scan time: 7.680 The best scores are: opt bits E(85289) XP_011534459 (OMIM: 606915) PREDICTED: probable G- ( 419) 2774 511.5 1.6e-144 XP_011534457 (OMIM: 606915) PREDICTED: probable G- ( 419) 2774 511.5 1.6e-144 XP_011534456 (OMIM: 606915) PREDICTED: probable G- ( 419) 2774 511.5 1.6e-144 XP_016866823 (OMIM: 606915) PREDICTED: probable G- ( 419) 2774 511.5 1.6e-144 XP_011534455 (OMIM: 606915) PREDICTED: probable G- ( 419) 2774 511.5 1.6e-144 XP_006715633 (OMIM: 606915) PREDICTED: probable G- ( 419) 2774 511.5 1.6e-144 NP_001137429 (OMIM: 606915) probable G-protein cou ( 419) 2774 511.5 1.6e-144 NP_110411 (OMIM: 606915) probable G-protein couple ( 419) 2774 511.5 1.6e-144 XP_011534461 (OMIM: 606915) PREDICTED: probable G- ( 419) 2774 511.5 1.6e-144 NP_009158 (OMIM: 604838) probable G-protein couple ( 372) 1361 256.6 7.4e-68 NP_001035262 (OMIM: 602164) 5-hydroxytryptamine re ( 360) 381 79.9 1.2e-14 NP_955525 (OMIM: 602164) 5-hydroxytryptamine recep ( 378) 381 79.9 1.2e-14 NP_001035259 (OMIM: 602164) 5-hydroxytryptamine re ( 387) 381 79.9 1.2e-14 NP_000861 (OMIM: 602164) 5-hydroxytryptamine recep ( 388) 381 79.9 1.2e-14 NP_001273339 (OMIM: 602164) 5-hydroxytryptamine re ( 411) 381 80.0 1.2e-14 NP_001035263 (OMIM: 602164) 5-hydroxytryptamine re ( 428) 381 80.0 1.3e-14 NP_000015 (OMIM: 109690,600807,601665) beta-2 adre ( 413) 367 77.4 7.2e-14 NP_150598 (OMIM: 606665) melanopsin isoform 1 [Hom ( 478) 336 71.9 3.8e-12 XP_016872445 (OMIM: 606665) PREDICTED: melanopsin ( 528) 336 72.0 4e-12 XP_016856349 (OMIM: 612250) PREDICTED: G-protein c ( 529) 336 72.0 4.1e-12 XP_005245113 (OMIM: 612250) PREDICTED: G-protein c ( 529) 336 72.0 4.1e-12 XP_011507679 (OMIM: 612250) PREDICTED: G-protein c ( 529) 336 72.0 4.1e-12 NP_001254539 (OMIM: 612250) G-protein coupled rece ( 529) 336 72.0 4.1e-12 XP_016856350 (OMIM: 612250) PREDICTED: G-protein c ( 529) 336 72.0 4.1e-12 XP_011507680 (OMIM: 612250) PREDICTED: G-protein c ( 529) 336 72.0 4.1e-12 XP_005245114 (OMIM: 612250) PREDICTED: G-protein c ( 529) 336 72.0 4.1e-12 XP_011507677 (OMIM: 612250) PREDICTED: G-protein c ( 529) 336 72.0 4.1e-12 NP_722561 (OMIM: 612250) G-protein coupled recepto ( 529) 336 72.0 4.1e-12 XP_016856351 (OMIM: 612250) PREDICTED: G-protein c ( 529) 336 72.0 4.1e-12 XP_011507678 (OMIM: 612250) PREDICTED: G-protein c ( 529) 336 72.0 4.1e-12 NP_001254540 (OMIM: 612250) G-protein coupled rece ( 546) 336 72.0 4.1e-12 XP_016856348 (OMIM: 612250) PREDICTED: G-protein c ( 549) 336 72.0 4.1e-12 XP_005245112 (OMIM: 612250) PREDICTED: G-protein c ( 549) 336 72.0 4.1e-12 NP_001254538 (OMIM: 612250) G-protein coupled rece ( 549) 336 72.0 4.1e-12 XP_011507673 (OMIM: 612250) PREDICTED: G-protein c ( 552) 336 72.0 4.2e-12 XP_011507675 (OMIM: 612250) PREDICTED: G-protein c ( 552) 336 72.0 4.2e-12 XP_011507674 (OMIM: 612250) PREDICTED: G-protein c ( 552) 336 72.0 4.2e-12 XP_011507672 (OMIM: 612250) PREDICTED: G-protein c ( 552) 336 72.0 4.2e-12 XP_006711314 (OMIM: 612250) PREDICTED: G-protein c ( 552) 336 72.0 4.2e-12 XP_016856347 (OMIM: 612250) PREDICTED: G-protein c ( 552) 336 72.0 4.2e-12 XP_006711316 (OMIM: 612250) PREDICTED: G-protein c ( 609) 336 72.1 4.4e-12 NP_859529 (OMIM: 607514,609044) free fatty acid re ( 377) 322 69.3 1.9e-11 NP_005949 (OMIM: 600665) melatonin receptor type 1 ( 350) 321 69.1 2e-11 NP_000862 (OMIM: 601109) 5-hydroxytryptamine recep ( 440) 315 68.1 5e-11 NP_057658 (OMIM: 126450,159900) D(2) dopamine rece ( 414) 313 67.7 6.2e-11 XP_016872785 (OMIM: 126450,159900) PREDICTED: D(2) ( 443) 313 67.7 6.4e-11 NP_000786 (OMIM: 126450,159900) D(2) dopamine rece ( 443) 313 67.7 6.4e-11 NP_000672 (OMIM: 104210) alpha-2A adrenergic recep ( 465) 313 67.8 6.6e-11 NP_000674 (OMIM: 104250) alpha-2C adrenergic recep ( 462) 312 67.6 7.5e-11 NP_071640 (OMIM: 142703) histamine H2 receptor iso ( 359) 310 67.1 8.2e-11 >>XP_011534459 (OMIM: 606915) PREDICTED: probable G-prot (419 aa) initn: 2774 init1: 2774 opt: 2774 Z-score: 2715.8 bits: 511.5 E(85289): 1.6e-144 Smith-Waterman score: 2774; 99.8% identity (100.0% similar) in 419 aa overlap (1-419:1-419) 10 20 30 40 50 60 pF1KB4 MVFSAVLTAFHTGTSNTTFVMYENTYMNITLPPPFQHPDLSPLLRYSFETMAPTGLSSLT ::::::::::::::::::::.::::::::::::::::::::::::::::::::::::::: XP_011 MVFSAVLTAFHTGTSNTTFVVYENTYMNITLPPPFQHPDLSPLLRYSFETMAPTGLSSLT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 VNSTAVPTTPAAFKSLNLPLQITLSAIMIFILFVSFLGNLVVCLMVYQKAAMRSAINILL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VNSTAVPTTPAAFKSLNLPLQITLSAIMIFILFVSFLGNLVVCLMVYQKAAMRSAINILL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 ASLAFADMLLAVLNMPFALVTILTTRWIFGKFFCRVSAMFFWLFVIEGVAILLIISIDRF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ASLAFADMLLAVLNMPFALVTILTTRWIFGKFFCRVSAMFFWLFVIEGVAILLIISIDRF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 LIIVQRQDKLNPYRAKVLIAVSWATSFCVAFPLAVGNPDLQIPSRAPQCVFGYTTNPGYQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LIIVQRQDKLNPYRAKVLIAVSWATSFCVAFPLAVGNPDLQIPSRAPQCVFGYTTNPGYQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 AYVILISLISFFIPFLVILYSFMGILNTLRHNALRIHSYPEGICLSQASKLGLMSLQRPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AYVILISLISFFIPFLVILYSFMGILNTLRHNALRIHSYPEGICLSQASKLGLMSLQRPF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 QMSIDMGFKTRAFTTILILFAVFIVCWAPFTTYSLVATFSKHFYYQHNFFEISTWLLWLC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QMSIDMGFKTRAFTTILILFAVFIVCWAPFTTYSLVATFSKHFYYQHNFFEISTWLLWLC 310 320 330 340 350 360 370 380 390 400 410 pF1KB4 YLKSALNPLIYYWRIKKFHDACLDMMPKSFKFLPQLPGHTKRRIRPSAVYVCGEHRTVV ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YLKSALNPLIYYWRIKKFHDACLDMMPKSFKFLPQLPGHTKRRIRPSAVYVCGEHRTVV 370 380 390 400 410 >>XP_011534457 (OMIM: 606915) PREDICTED: probable G-prot (419 aa) initn: 2774 init1: 2774 opt: 2774 Z-score: 2715.8 bits: 511.5 E(85289): 1.6e-144 Smith-Waterman score: 2774; 99.8% identity (100.0% similar) in 419 aa overlap (1-419:1-419) 10 20 30 40 50 60 pF1KB4 MVFSAVLTAFHTGTSNTTFVMYENTYMNITLPPPFQHPDLSPLLRYSFETMAPTGLSSLT ::::::::::::::::::::.::::::::::::::::::::::::::::::::::::::: XP_011 MVFSAVLTAFHTGTSNTTFVVYENTYMNITLPPPFQHPDLSPLLRYSFETMAPTGLSSLT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 VNSTAVPTTPAAFKSLNLPLQITLSAIMIFILFVSFLGNLVVCLMVYQKAAMRSAINILL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VNSTAVPTTPAAFKSLNLPLQITLSAIMIFILFVSFLGNLVVCLMVYQKAAMRSAINILL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 ASLAFADMLLAVLNMPFALVTILTTRWIFGKFFCRVSAMFFWLFVIEGVAILLIISIDRF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ASLAFADMLLAVLNMPFALVTILTTRWIFGKFFCRVSAMFFWLFVIEGVAILLIISIDRF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 LIIVQRQDKLNPYRAKVLIAVSWATSFCVAFPLAVGNPDLQIPSRAPQCVFGYTTNPGYQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LIIVQRQDKLNPYRAKVLIAVSWATSFCVAFPLAVGNPDLQIPSRAPQCVFGYTTNPGYQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 AYVILISLISFFIPFLVILYSFMGILNTLRHNALRIHSYPEGICLSQASKLGLMSLQRPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AYVILISLISFFIPFLVILYSFMGILNTLRHNALRIHSYPEGICLSQASKLGLMSLQRPF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 QMSIDMGFKTRAFTTILILFAVFIVCWAPFTTYSLVATFSKHFYYQHNFFEISTWLLWLC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QMSIDMGFKTRAFTTILILFAVFIVCWAPFTTYSLVATFSKHFYYQHNFFEISTWLLWLC 310 320 330 340 350 360 370 380 390 400 410 pF1KB4 YLKSALNPLIYYWRIKKFHDACLDMMPKSFKFLPQLPGHTKRRIRPSAVYVCGEHRTVV ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YLKSALNPLIYYWRIKKFHDACLDMMPKSFKFLPQLPGHTKRRIRPSAVYVCGEHRTVV 370 380 390 400 410 >>XP_011534456 (OMIM: 606915) PREDICTED: probable G-prot (419 aa) initn: 2774 init1: 2774 opt: 2774 Z-score: 2715.8 bits: 511.5 E(85289): 1.6e-144 Smith-Waterman score: 2774; 99.8% identity (100.0% similar) in 419 aa overlap (1-419:1-419) 10 20 30 40 50 60 pF1KB4 MVFSAVLTAFHTGTSNTTFVMYENTYMNITLPPPFQHPDLSPLLRYSFETMAPTGLSSLT ::::::::::::::::::::.::::::::::::::::::::::::::::::::::::::: XP_011 MVFSAVLTAFHTGTSNTTFVVYENTYMNITLPPPFQHPDLSPLLRYSFETMAPTGLSSLT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 VNSTAVPTTPAAFKSLNLPLQITLSAIMIFILFVSFLGNLVVCLMVYQKAAMRSAINILL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VNSTAVPTTPAAFKSLNLPLQITLSAIMIFILFVSFLGNLVVCLMVYQKAAMRSAINILL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 ASLAFADMLLAVLNMPFALVTILTTRWIFGKFFCRVSAMFFWLFVIEGVAILLIISIDRF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ASLAFADMLLAVLNMPFALVTILTTRWIFGKFFCRVSAMFFWLFVIEGVAILLIISIDRF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 LIIVQRQDKLNPYRAKVLIAVSWATSFCVAFPLAVGNPDLQIPSRAPQCVFGYTTNPGYQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LIIVQRQDKLNPYRAKVLIAVSWATSFCVAFPLAVGNPDLQIPSRAPQCVFGYTTNPGYQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 AYVILISLISFFIPFLVILYSFMGILNTLRHNALRIHSYPEGICLSQASKLGLMSLQRPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AYVILISLISFFIPFLVILYSFMGILNTLRHNALRIHSYPEGICLSQASKLGLMSLQRPF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 QMSIDMGFKTRAFTTILILFAVFIVCWAPFTTYSLVATFSKHFYYQHNFFEISTWLLWLC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QMSIDMGFKTRAFTTILILFAVFIVCWAPFTTYSLVATFSKHFYYQHNFFEISTWLLWLC 310 320 330 340 350 360 370 380 390 400 410 pF1KB4 YLKSALNPLIYYWRIKKFHDACLDMMPKSFKFLPQLPGHTKRRIRPSAVYVCGEHRTVV ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YLKSALNPLIYYWRIKKFHDACLDMMPKSFKFLPQLPGHTKRRIRPSAVYVCGEHRTVV 370 380 390 400 410 >>XP_016866823 (OMIM: 606915) PREDICTED: probable G-prot (419 aa) initn: 2774 init1: 2774 opt: 2774 Z-score: 2715.8 bits: 511.5 E(85289): 1.6e-144 Smith-Waterman score: 2774; 99.8% identity (100.0% similar) in 419 aa overlap (1-419:1-419) 10 20 30 40 50 60 pF1KB4 MVFSAVLTAFHTGTSNTTFVMYENTYMNITLPPPFQHPDLSPLLRYSFETMAPTGLSSLT ::::::::::::::::::::.::::::::::::::::::::::::::::::::::::::: XP_016 MVFSAVLTAFHTGTSNTTFVVYENTYMNITLPPPFQHPDLSPLLRYSFETMAPTGLSSLT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 VNSTAVPTTPAAFKSLNLPLQITLSAIMIFILFVSFLGNLVVCLMVYQKAAMRSAINILL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VNSTAVPTTPAAFKSLNLPLQITLSAIMIFILFVSFLGNLVVCLMVYQKAAMRSAINILL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 ASLAFADMLLAVLNMPFALVTILTTRWIFGKFFCRVSAMFFWLFVIEGVAILLIISIDRF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ASLAFADMLLAVLNMPFALVTILTTRWIFGKFFCRVSAMFFWLFVIEGVAILLIISIDRF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 LIIVQRQDKLNPYRAKVLIAVSWATSFCVAFPLAVGNPDLQIPSRAPQCVFGYTTNPGYQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LIIVQRQDKLNPYRAKVLIAVSWATSFCVAFPLAVGNPDLQIPSRAPQCVFGYTTNPGYQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 AYVILISLISFFIPFLVILYSFMGILNTLRHNALRIHSYPEGICLSQASKLGLMSLQRPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AYVILISLISFFIPFLVILYSFMGILNTLRHNALRIHSYPEGICLSQASKLGLMSLQRPF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 QMSIDMGFKTRAFTTILILFAVFIVCWAPFTTYSLVATFSKHFYYQHNFFEISTWLLWLC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QMSIDMGFKTRAFTTILILFAVFIVCWAPFTTYSLVATFSKHFYYQHNFFEISTWLLWLC 310 320 330 340 350 360 370 380 390 400 410 pF1KB4 YLKSALNPLIYYWRIKKFHDACLDMMPKSFKFLPQLPGHTKRRIRPSAVYVCGEHRTVV ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YLKSALNPLIYYWRIKKFHDACLDMMPKSFKFLPQLPGHTKRRIRPSAVYVCGEHRTVV 370 380 390 400 410 >>XP_011534455 (OMIM: 606915) PREDICTED: probable G-prot (419 aa) initn: 2774 init1: 2774 opt: 2774 Z-score: 2715.8 bits: 511.5 E(85289): 1.6e-144 Smith-Waterman score: 2774; 99.8% identity (100.0% similar) in 419 aa overlap (1-419:1-419) 10 20 30 40 50 60 pF1KB4 MVFSAVLTAFHTGTSNTTFVMYENTYMNITLPPPFQHPDLSPLLRYSFETMAPTGLSSLT ::::::::::::::::::::.::::::::::::::::::::::::::::::::::::::: XP_011 MVFSAVLTAFHTGTSNTTFVVYENTYMNITLPPPFQHPDLSPLLRYSFETMAPTGLSSLT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 VNSTAVPTTPAAFKSLNLPLQITLSAIMIFILFVSFLGNLVVCLMVYQKAAMRSAINILL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VNSTAVPTTPAAFKSLNLPLQITLSAIMIFILFVSFLGNLVVCLMVYQKAAMRSAINILL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 ASLAFADMLLAVLNMPFALVTILTTRWIFGKFFCRVSAMFFWLFVIEGVAILLIISIDRF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ASLAFADMLLAVLNMPFALVTILTTRWIFGKFFCRVSAMFFWLFVIEGVAILLIISIDRF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 LIIVQRQDKLNPYRAKVLIAVSWATSFCVAFPLAVGNPDLQIPSRAPQCVFGYTTNPGYQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LIIVQRQDKLNPYRAKVLIAVSWATSFCVAFPLAVGNPDLQIPSRAPQCVFGYTTNPGYQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 AYVILISLISFFIPFLVILYSFMGILNTLRHNALRIHSYPEGICLSQASKLGLMSLQRPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AYVILISLISFFIPFLVILYSFMGILNTLRHNALRIHSYPEGICLSQASKLGLMSLQRPF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 QMSIDMGFKTRAFTTILILFAVFIVCWAPFTTYSLVATFSKHFYYQHNFFEISTWLLWLC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QMSIDMGFKTRAFTTILILFAVFIVCWAPFTTYSLVATFSKHFYYQHNFFEISTWLLWLC 310 320 330 340 350 360 370 380 390 400 410 pF1KB4 YLKSALNPLIYYWRIKKFHDACLDMMPKSFKFLPQLPGHTKRRIRPSAVYVCGEHRTVV ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YLKSALNPLIYYWRIKKFHDACLDMMPKSFKFLPQLPGHTKRRIRPSAVYVCGEHRTVV 370 380 390 400 410 >>XP_006715633 (OMIM: 606915) PREDICTED: probable G-prot (419 aa) initn: 2774 init1: 2774 opt: 2774 Z-score: 2715.8 bits: 511.5 E(85289): 1.6e-144 Smith-Waterman score: 2774; 99.8% identity (100.0% similar) in 419 aa overlap (1-419:1-419) 10 20 30 40 50 60 pF1KB4 MVFSAVLTAFHTGTSNTTFVMYENTYMNITLPPPFQHPDLSPLLRYSFETMAPTGLSSLT ::::::::::::::::::::.::::::::::::::::::::::::::::::::::::::: XP_006 MVFSAVLTAFHTGTSNTTFVVYENTYMNITLPPPFQHPDLSPLLRYSFETMAPTGLSSLT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 VNSTAVPTTPAAFKSLNLPLQITLSAIMIFILFVSFLGNLVVCLMVYQKAAMRSAINILL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VNSTAVPTTPAAFKSLNLPLQITLSAIMIFILFVSFLGNLVVCLMVYQKAAMRSAINILL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 ASLAFADMLLAVLNMPFALVTILTTRWIFGKFFCRVSAMFFWLFVIEGVAILLIISIDRF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ASLAFADMLLAVLNMPFALVTILTTRWIFGKFFCRVSAMFFWLFVIEGVAILLIISIDRF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 LIIVQRQDKLNPYRAKVLIAVSWATSFCVAFPLAVGNPDLQIPSRAPQCVFGYTTNPGYQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LIIVQRQDKLNPYRAKVLIAVSWATSFCVAFPLAVGNPDLQIPSRAPQCVFGYTTNPGYQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 AYVILISLISFFIPFLVILYSFMGILNTLRHNALRIHSYPEGICLSQASKLGLMSLQRPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AYVILISLISFFIPFLVILYSFMGILNTLRHNALRIHSYPEGICLSQASKLGLMSLQRPF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 QMSIDMGFKTRAFTTILILFAVFIVCWAPFTTYSLVATFSKHFYYQHNFFEISTWLLWLC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QMSIDMGFKTRAFTTILILFAVFIVCWAPFTTYSLVATFSKHFYYQHNFFEISTWLLWLC 310 320 330 340 350 360 370 380 390 400 410 pF1KB4 YLKSALNPLIYYWRIKKFHDACLDMMPKSFKFLPQLPGHTKRRIRPSAVYVCGEHRTVV ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 YLKSALNPLIYYWRIKKFHDACLDMMPKSFKFLPQLPGHTKRRIRPSAVYVCGEHRTVV 370 380 390 400 410 >>NP_001137429 (OMIM: 606915) probable G-protein coupled (419 aa) initn: 2774 init1: 2774 opt: 2774 Z-score: 2715.8 bits: 511.5 E(85289): 1.6e-144 Smith-Waterman score: 2774; 99.8% identity (100.0% similar) in 419 aa overlap (1-419:1-419) 10 20 30 40 50 60 pF1KB4 MVFSAVLTAFHTGTSNTTFVMYENTYMNITLPPPFQHPDLSPLLRYSFETMAPTGLSSLT ::::::::::::::::::::.::::::::::::::::::::::::::::::::::::::: NP_001 MVFSAVLTAFHTGTSNTTFVVYENTYMNITLPPPFQHPDLSPLLRYSFETMAPTGLSSLT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 VNSTAVPTTPAAFKSLNLPLQITLSAIMIFILFVSFLGNLVVCLMVYQKAAMRSAINILL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VNSTAVPTTPAAFKSLNLPLQITLSAIMIFILFVSFLGNLVVCLMVYQKAAMRSAINILL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 ASLAFADMLLAVLNMPFALVTILTTRWIFGKFFCRVSAMFFWLFVIEGVAILLIISIDRF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ASLAFADMLLAVLNMPFALVTILTTRWIFGKFFCRVSAMFFWLFVIEGVAILLIISIDRF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 LIIVQRQDKLNPYRAKVLIAVSWATSFCVAFPLAVGNPDLQIPSRAPQCVFGYTTNPGYQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LIIVQRQDKLNPYRAKVLIAVSWATSFCVAFPLAVGNPDLQIPSRAPQCVFGYTTNPGYQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 AYVILISLISFFIPFLVILYSFMGILNTLRHNALRIHSYPEGICLSQASKLGLMSLQRPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AYVILISLISFFIPFLVILYSFMGILNTLRHNALRIHSYPEGICLSQASKLGLMSLQRPF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 QMSIDMGFKTRAFTTILILFAVFIVCWAPFTTYSLVATFSKHFYYQHNFFEISTWLLWLC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QMSIDMGFKTRAFTTILILFAVFIVCWAPFTTYSLVATFSKHFYYQHNFFEISTWLLWLC 310 320 330 340 350 360 370 380 390 400 410 pF1KB4 YLKSALNPLIYYWRIKKFHDACLDMMPKSFKFLPQLPGHTKRRIRPSAVYVCGEHRTVV ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YLKSALNPLIYYWRIKKFHDACLDMMPKSFKFLPQLPGHTKRRIRPSAVYVCGEHRTVV 370 380 390 400 410 >>NP_110411 (OMIM: 606915) probable G-protein coupled re (419 aa) initn: 2774 init1: 2774 opt: 2774 Z-score: 2715.8 bits: 511.5 E(85289): 1.6e-144 Smith-Waterman score: 2774; 99.8% identity (100.0% similar) in 419 aa overlap (1-419:1-419) 10 20 30 40 50 60 pF1KB4 MVFSAVLTAFHTGTSNTTFVMYENTYMNITLPPPFQHPDLSPLLRYSFETMAPTGLSSLT ::::::::::::::::::::.::::::::::::::::::::::::::::::::::::::: NP_110 MVFSAVLTAFHTGTSNTTFVVYENTYMNITLPPPFQHPDLSPLLRYSFETMAPTGLSSLT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 VNSTAVPTTPAAFKSLNLPLQITLSAIMIFILFVSFLGNLVVCLMVYQKAAMRSAINILL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_110 VNSTAVPTTPAAFKSLNLPLQITLSAIMIFILFVSFLGNLVVCLMVYQKAAMRSAINILL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 ASLAFADMLLAVLNMPFALVTILTTRWIFGKFFCRVSAMFFWLFVIEGVAILLIISIDRF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_110 ASLAFADMLLAVLNMPFALVTILTTRWIFGKFFCRVSAMFFWLFVIEGVAILLIISIDRF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 LIIVQRQDKLNPYRAKVLIAVSWATSFCVAFPLAVGNPDLQIPSRAPQCVFGYTTNPGYQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_110 LIIVQRQDKLNPYRAKVLIAVSWATSFCVAFPLAVGNPDLQIPSRAPQCVFGYTTNPGYQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 AYVILISLISFFIPFLVILYSFMGILNTLRHNALRIHSYPEGICLSQASKLGLMSLQRPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_110 AYVILISLISFFIPFLVILYSFMGILNTLRHNALRIHSYPEGICLSQASKLGLMSLQRPF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 QMSIDMGFKTRAFTTILILFAVFIVCWAPFTTYSLVATFSKHFYYQHNFFEISTWLLWLC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_110 QMSIDMGFKTRAFTTILILFAVFIVCWAPFTTYSLVATFSKHFYYQHNFFEISTWLLWLC 310 320 330 340 350 360 370 380 390 400 410 pF1KB4 YLKSALNPLIYYWRIKKFHDACLDMMPKSFKFLPQLPGHTKRRIRPSAVYVCGEHRTVV ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_110 YLKSALNPLIYYWRIKKFHDACLDMMPKSFKFLPQLPGHTKRRIRPSAVYVCGEHRTVV 370 380 390 400 410 >>XP_011534461 (OMIM: 606915) PREDICTED: probable G-prot (419 aa) initn: 2774 init1: 2774 opt: 2774 Z-score: 2715.8 bits: 511.5 E(85289): 1.6e-144 Smith-Waterman score: 2774; 99.8% identity (100.0% similar) in 419 aa overlap (1-419:1-419) 10 20 30 40 50 60 pF1KB4 MVFSAVLTAFHTGTSNTTFVMYENTYMNITLPPPFQHPDLSPLLRYSFETMAPTGLSSLT ::::::::::::::::::::.::::::::::::::::::::::::::::::::::::::: XP_011 MVFSAVLTAFHTGTSNTTFVVYENTYMNITLPPPFQHPDLSPLLRYSFETMAPTGLSSLT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 VNSTAVPTTPAAFKSLNLPLQITLSAIMIFILFVSFLGNLVVCLMVYQKAAMRSAINILL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VNSTAVPTTPAAFKSLNLPLQITLSAIMIFILFVSFLGNLVVCLMVYQKAAMRSAINILL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 ASLAFADMLLAVLNMPFALVTILTTRWIFGKFFCRVSAMFFWLFVIEGVAILLIISIDRF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ASLAFADMLLAVLNMPFALVTILTTRWIFGKFFCRVSAMFFWLFVIEGVAILLIISIDRF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 LIIVQRQDKLNPYRAKVLIAVSWATSFCVAFPLAVGNPDLQIPSRAPQCVFGYTTNPGYQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LIIVQRQDKLNPYRAKVLIAVSWATSFCVAFPLAVGNPDLQIPSRAPQCVFGYTTNPGYQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 AYVILISLISFFIPFLVILYSFMGILNTLRHNALRIHSYPEGICLSQASKLGLMSLQRPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AYVILISLISFFIPFLVILYSFMGILNTLRHNALRIHSYPEGICLSQASKLGLMSLQRPF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 QMSIDMGFKTRAFTTILILFAVFIVCWAPFTTYSLVATFSKHFYYQHNFFEISTWLLWLC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QMSIDMGFKTRAFTTILILFAVFIVCWAPFTTYSLVATFSKHFYYQHNFFEISTWLLWLC 310 320 330 340 350 360 370 380 390 400 410 pF1KB4 YLKSALNPLIYYWRIKKFHDACLDMMPKSFKFLPQLPGHTKRRIRPSAVYVCGEHRTVV ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YLKSALNPLIYYWRIKKFHDACLDMMPKSFKFLPQLPGHTKRRIRPSAVYVCGEHRTVV 370 380 390 400 410 >>NP_009158 (OMIM: 604838) probable G-protein coupled re (372 aa) initn: 1382 init1: 1360 opt: 1361 Z-score: 1339.2 bits: 256.6 E(85289): 7.4e-68 Smith-Waterman score: 1361; 55.2% identity (83.4% similar) in 344 aa overlap (76-419:29-372) 50 60 70 80 90 100 pF1KB4 YSFETMAPTGLSSLTVNSTAVPTTPAAFKSLNLPLQITLSAIMIFILFVSFLGNLVVCLM : ::.:.:. .:... :.:::: :::.. NP_009 MACNSTSLEAYTYLLLNTSNASDSGSTQLPAPLRISLAIVMLLMTVVGFLGNTVVCII 10 20 30 40 50 110 120 130 140 150 160 pF1KB4 VYQKAAMRSAINILLASLAFADMLLAVLNMPFALVTILTTRWIFGKFFCRVSAMFFWLFV :::. :::::::.:::.:::.:..:.. :::. ::..:.:: :: :::.:: ..:.:: NP_009 VYQRPAMRSAINLLLATLAFSDIMLSLCCMPFTAVTLITVRWHFGDHFCRLSATLYWFFV 60 70 80 90 100 110 170 180 190 200 210 220 pF1KB4 IEGVAILLIISIDRFLIIVQRQDKLNPYRAKVLIAVSWATSFCVAFPLAVGNPDLQIPSR .::::::::::.::::::::::::::: ::::.:::::. :::.: : .: ...:.: NP_009 LEGVAILLIISVDRFLIIVQRQDKLNPRRAKVIIAVSWVLSFCIAGPSLTGWTLVEVPAR 120 130 140 150 160 170 230 240 250 260 270 280 pF1KB4 APQCVFGYTTNPGYQAYVILISLISFFIPFLVILYSFMGILNTLRHNALRIHSYPEGICL :::::.::: :. .:::. . . :: :: :.: ..: ::::.:.::.:.:. ... : NP_009 APQCVLGYTELPADRAYVVTLVVAVFFAPFGVMLCAYMCILNTVRKNAVRVHNQSDSLDL 180 190 200 210 220 230 290 300 310 320 330 340 pF1KB4 SQASKLGLMSLQRPFQMSIDMGFKTRAFTTILILFAVFIVCWAPFTTYSLVATFSKHFYY : .. :: ::: :.:.:..:::.:::::::::. : .:: : ..:::...::..:: NP_009 RQLTRAGLRRLQRQQQVSVDLSFKTKAFTTILILFVGFSLCWLPHSVYSLLSVFSQRFYC 240 250 260 270 280 290 350 360 370 380 390 400 pF1KB4 QHNFFEISTWLLWLCYLKSALNPLIYYWRIKKFHDACLDMMPKSFKFLPQLPGHTKRRIR .:. :: .::: ::::..::..: ::::::..::....:..:..::..: . .:::. NP_009 GSSFYATSTCVLWLSYLKSVFNPIVYCWRIKKFREACIELLPQTFQILPKVPERIRRRIQ 300 310 320 330 340 350 410 pF1KB4 PSAVYVCGEHRTVV ::.::::.:....: NP_009 PSTVYVCNENQSAV 360 370 419 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 14:41:41 2016 done: Thu Nov 3 14:41:43 2016 Total Scan time: 7.680 Total Display time: 0.050 Function used was FASTA [36.3.4 Apr, 2011]