FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB4275, 574 aa 1>>>pF1KB4275 574 - 574 aa - 574 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 12.1101+/-0.00112; mu= -9.8096+/- 0.068 mean_var=469.2624+/-95.971, 0's: 0 Z-trim(117.1): 97 B-trim: 479 in 1/51 Lambda= 0.059206 statistics sampled from 17729 (17826) to 17729 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.811), E-opt: 0.2 (0.548), width: 16 Scan time: 4.440 The best scores are: opt bits E(32554) CCDS8587.1 FOXJ2 gene_id:55810|Hs108|chr12 ( 574) 4105 364.9 1.5e-100 CCDS55594.1 FOXJ3 gene_id:22887|Hs108|chr1 ( 588) 1265 122.4 1.6e-27 CCDS30689.1 FOXJ3 gene_id:22887|Hs108|chr1 ( 622) 784 81.3 3.9e-15 >>CCDS8587.1 FOXJ2 gene_id:55810|Hs108|chr12 (574 aa) initn: 4105 init1: 4105 opt: 4105 Z-score: 1918.7 bits: 364.9 E(32554): 1.5e-100 Smith-Waterman score: 4105; 100.0% identity (100.0% similar) in 574 aa overlap (1-574:1-574) 10 20 30 40 50 60 pF1KB4 MASDLESSLTSIDWLPQLTLRATIEKLGSASQAGPPGSSRKCSPGSPTDPNATLSKDEAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS85 MASDLESSLTSIDWLPQLTLRATIEKLGSASQAGPPGSSRKCSPGSPTDPNATLSKDEAA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 VHQDGKPRYSYATLITYAINSSPAKKMTLSEIYRWICDNFPYYKNAGIGWKNSIRHNLSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS85 VHQDGKPRYSYATLITYAINSSPAKKMTLSEIYRWICDNFPYYKNAGIGWKNSIRHNLSL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 NKCFRKVPRPRDDPGKGSYWTIDTCPDISRKRRHPPDDDLSQDSPEQEASKSPRGGVAGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS85 NKCFRKVPRPRDDPGKGSYWTIDTCPDISRKRRHPPDDDLSQDSPEQEASKSPRGGVAGS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 GEASLPPEGNPQMSLQSPTSIASYSQGTGSVDGGAVAAGASGRESAEGPPPLYNTNHDFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS85 GEASLPPEGNPQMSLQSPTSIASYSQGTGSVDGGAVAAGASGRESAEGPPPLYNTNHDFK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 FSYSEINFQDLSWSFRNLYKSMLEKSSSSSQHGFSSLLGDIPPSNNYYMYQQQQPPPPQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS85 FSYSEINFQDLSWSFRNLYKSMLEKSSSSSQHGFSSLLGDIPPSNNYYMYQQQQPPPPQQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 QQQQQQPPQPPPQQSQPQQQQAPAQGPSAVGGAPPLHTPSTDGCTPPGGKQAGAEGYGPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS85 QQQQQQPPQPPPQQSQPQQQQAPAQGPSAVGGAPPLHTPSTDGCTPPGGKQAGAEGYGPP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB4 PVMAMHPPPLQHGGYHPHQHHPHSHPAQQPPPPQPQAQGQAPINNTGFAFPSDWCSNIDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS85 PVMAMHPPPLQHGGYHPHQHHPHSHPAQQPPPPQPQAQGQAPINNTGFAFPSDWCSNIDS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB4 LKESFKMVNRLNWSSIEQSQFSELMESLRQAEQKNWTLDQHHIANLCDSLNHFLTQTGHV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS85 LKESFKMVNRLNWSSIEQSQFSELMESLRQAEQKNWTLDQHHIANLCDSLNHFLTQTGHV 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB4 PPQGGTHRPPAPARIADSCALTSGKQESAMSQVNSYGHPQAPHLYPGPSPMYPIPTQDSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS85 PPQGGTHRPPAPARIADSCALTSGKQESAMSQVNSYGHPQAPHLYPGPSPMYPIPTQDSA 490 500 510 520 530 540 550 560 570 pF1KB4 GYNRPAHHMVPRPSVPPPGANEEIPDDFDWDLIT :::::::::::::::::::::::::::::::::: CCDS85 GYNRPAHHMVPRPSVPPPGANEEIPDDFDWDLIT 550 560 570 >>CCDS55594.1 FOXJ3 gene_id:22887|Hs108|chr1 (588 aa) initn: 1255 init1: 562 opt: 1265 Z-score: 607.5 bits: 122.4 E(32554): 1.6e-27 Smith-Waterman score: 1285; 40.2% identity (64.4% similar) in 612 aa overlap (1-573:16-587) 10 20 30 40 pF1KB4 MASDLESSLTSIDWLPQLTLRATIEKLGSASQAGPPGSSRKCSPG :.:.:::::::.:::::::.::.:.: ....: : :.: . CCDS55 MGLYGQACPSVTSLRMTSELESSLTSMDWLPQLTMRAAIQKSDATQNAHGTGISKK---N 10 20 30 40 50 50 60 70 80 90 100 pF1KB4 SPTDPNATLSKDEAAVHQDGKPRYSYATLITYAINSSPAKKMTLSEIYRWICDNFPYYKN . :::.::...:. :.:::: ::::.:::.:::::: :::::::::.:::::::::.. CCDS55 ALLDPNTTLDQEEVQQHKDGKPPYSYASLITFAINSSPKKKMTLSEIYQWICDNFPYYRE 60 70 80 90 100 110 110 120 130 140 150 160 pF1KB4 AGIGWKNSIRHNLSLNKCFRKVPRPRDDPGKGSYWTIDTCP--DI--SR-KRRHPPDDDL :: :::::::::::::::: :::: .:::::::::.::: : :. .: :.: . . CCDS55 AGSGWKNSIRHNLSLNKCFLKVPRSKDDPGKGSYWAIDTNPKEDVLPTRPKKRARSVERV 120 130 140 150 160 170 170 180 190 200 210 220 pF1KB4 SQDSPEQEASKSPRGGVAGSGEASLPPEGNPQMSLQSPTSIASYSQGTGSVDGGAVAAGA . . .:..: ::: .: . :: .. ...:.: :. ::. :. . .:. . CCDS55 TLYNTDQDGSDSPR----SSLNNSLSDQSLASVNLNSVGSVHSYTPVTSHPE--SVSQSL 180 190 200 210 220 230 230 240 250 260 pF1KB4 SGRESAEGPPPLYNT-NHDFKFSYSEINFQDLSWSFRNLYKSMLEKS----------SSS . ... : :: ..: .. .:: ::.::: :::.::::..:.: : : CCDS55 TPQQQ-----PQYNLPERDKQLLFSEYNFEDLSASFRSLYKSVFEQSLSQQGLMNIPSES 240 250 260 270 280 270 280 290 300 310 320 pF1KB4 SQHGFSSLLGDIPPSNNY--YMYQQQQPPPPQQQQQQQQPPQPPPQQ---SQPQQQQAPA ::.. .: . ::.. . ...:. .. . . . : :.::.. :. CCDS55 SQQSHTSCTYQHSPSSTVSTHPHSNQSSLSNSHGSGLNTTGSNSVAQVSLSHPQMHTQPS 290 300 310 320 330 340 330 340 350 360 370 380 pF1KB4 QGPSAVGGAPPLHTPSTDGCTPPGGKQAGAEGYGPPPVMAMHPPPLQHGGYHP-HQHHPH : . : : :. . : .: .. .: : .:: : :: .:: :::. CCDS55 PHPPHRPHGLPQH-PQRSPHPAPHPQQH-SQLQSPHP---QHPSPHQHIQHHPNHQHQTL 350 360 370 380 390 400 390 400 410 420 430 440 pF1KB4 SHPAQQPPPPQPQAQGQAPINNTGFAFPSDWCSNIDSLKESFKMVNRLNWSSIEQSQFSE .: : ::::: :.. .. ..: :: ...: :::: .... .:::... :::. CCDS55 TH--QAPPPPQ-QVSCNSGVSN-------DWYATLDMLKESCRIASSVNWSDVDLSQFQG 410 420 430 440 450 450 460 470 480 490 pF1KB4 LMESLRQAEQKNWTLDQHHIANLCDSLNHFLTQTGHVPPQG--------GTHRPPAPAR- ::::.:::. :::.::: ..:.::.:::.:.:::: . :. :. .: :.. CCDS55 LMESMRQADLKNWSLDQVQFADLCSSLNQFFTQTGLIHSQSNVQQNVCHGAMHPTKPSQH 460 470 480 490 500 510 500 510 520 530 540 550 pF1KB4 IADSCALTSGKQESAMSQVNSYGHPQAPHLYPGPSPMYPIPTQDSAGYNRPAH--HMVP- :. . ...:. : . :.:. :. :. . ::..: . ::.: CCDS55 IGTGNLYIDSRQNLPPSVMPPPGYPHIPQALSTPGTTM-------AGHHRAMNQQHMMPS 520 530 540 550 560 560 570 pF1KB4 -----RPSVPPPGANEEIPDDFDWDLIT : :.:: ..: :::::: : CCDS55 QAFQMRRSLPP----DDIQDDFDWDSIV 570 580 >>CCDS30689.1 FOXJ3 gene_id:22887|Hs108|chr1 (622 aa) initn: 1146 init1: 562 opt: 784 Z-score: 385.2 bits: 81.3 E(32554): 3.9e-15 Smith-Waterman score: 1232; 39.4% identity (62.7% similar) in 632 aa overlap (1-570:16-618) 10 20 30 40 pF1KB4 MASDLESSLTSIDWLPQLTLRATIEKLGSASQAGPPGSSRKCSPG :.:.:::::::.:::::::.::.:.: ....: : :.: . CCDS30 MGLYGQACPSVTSLRMTSELESSLTSMDWLPQLTMRAAIQKSDATQNAHGTGISKK---N 10 20 30 40 50 50 60 70 80 90 100 pF1KB4 SPTDPNATLSKDEAAVHQDGKPRYSYATLITYAINSSPAKKMTLSEIYRWICDNFPYYKN . :::.::...:. :.:::: ::::.:::.:::::: :::::::::.:::::::::.. CCDS30 ALLDPNTTLDQEEVQQHKDGKPPYSYASLITFAINSSPKKKMTLSEIYQWICDNFPYYRE 60 70 80 90 100 110 110 120 130 140 150 pF1KB4 AGIGWKNSIRHNLSLNKCFRKVPRPRDDPGKGSYWTIDTCP--DI----SRKR-----RH :: :::::::::::::::: :::: .:::::::::.::: : :. .:: : CCDS30 AGSGWKNSIRHNLSLNKCFLKVPRSKDDPGKGSYWAIDTNPKEDVLPTRPKKRARSVERA 120 130 140 150 160 170 160 170 180 190 200 pF1KB4 PPDDDLSQDSPEQE----ASKSPRGGVAG-SGEASL---PPEGN--PQMSLQ---SPTSI ....:: .: .: :: .. .....: .:. :. ::. : :. CCDS30 STPYSIDSDSLGMECIISGSASPTLAINTVTNKVTLYNTDQDGSDSPRSSLNNSLSDQSL 180 190 200 210 220 230 210 220 230 240 250 pF1KB4 ASYSQGT-GSVDGGAVAAGASGRESAEGPP---PLYNT-NHDFKFSYSEINFQDLSWSFR :: . .. ::: . . ... : : : :: ..: .. .:: ::.::: ::: CCDS30 ASVNLNSVGSVHSYTPVTSHPESVSQSLTPQQQPQYNLPERDKQLLFSEYNFEDLSASFR 240 250 260 270 280 290 260 270 280 290 300 pF1KB4 NLYKSMLEKS----------SSSSQHGFSSLLGDIPPSNNY--YMYQQQQPPPPQQQQQQ .::::..:.: : :::.. .: . ::.. . ...:. .. . CCDS30 SLYKSVFEQSLSQQGLMNIPSESSQQSHTSCTYQHSPSSTVSTHPHSNQSSLSNSHGSGL 300 310 320 330 340 350 310 320 330 340 350 360 pF1KB4 QQPPQPPPQQ---SQPQQQQAPAQGPSAVGGAPPLHTPSTDGCTPPGGKQAGAEGYGPPP . . : :.::.. :. : . : : :. . : .: .. .: : CCDS30 NTTGSNSVAQVSLSHPQMHTQPSPHPPHRPHGLPQH-PQRSPHPAPHPQQH-SQLQSPHP 360 370 380 390 400 410 370 380 390 400 410 420 pF1KB4 VMAMHPPPLQHGGYHP-HQHHPHSHPAQQPPPPQPQAQGQAPINNTGFAFPSDWCSNIDS .:: : :: .:: :::. .: : ::::: :.. .. ..: :: ...: CCDS30 ---QHPSPHQHIQHHPNHQHQTLTH--QAPPPPQ-QVSCNSGVSN-------DWYATLDM 420 430 440 450 460 430 440 450 460 470 480 pF1KB4 LKESFKMVNRLNWSSIEQSQFSELMESLRQAEQKNWTLDQHHIANLCDSLNHFLTQTGHV :::: .... .:::... :::. ::::.:::. :::.::: ..:.::.:::.:.:::: . CCDS30 LKESCRIASSVNWSDVDLSQFQGLMESMRQADLKNWSLDQVQFADLCSSLNQFFTQTGLI 470 480 490 500 510 520 490 500 510 520 530 pF1KB4 PPQG--------GTHRPPAPAR-IADSCALTSGKQESAMSQVNSYGHPQAPHLYPGPSPM :. :. .: :.. :. . ...:. : . :.:. :. :. CCDS30 HSQSNVQQNVCHGAMHPTKPSQHIGTGNLYIDSRQNLPPSVMPPPGYPHIPQALSTPGTT 530 540 550 560 570 580 540 550 560 570 pF1KB4 YPIPTQDSAGYNRPAH--HMVP------RPSVPPPGANEEIPDDFDWDLIT . ::..: . ::.: : :.:: ..: ::::: CCDS30 M-------AGHHRAMNQQHMMPSQAFQMRRSLPP----DDIQDDFDWDSIV 590 600 610 620 574 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 21:32:23 2016 done: Thu Nov 3 21:32:23 2016 Total Scan time: 4.440 Total Display time: 0.040 Function used was FASTA [36.3.4 Apr, 2011]