FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB4277, 425 aa 1>>>pF1KB4277 425 - 425 aa - 425 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.6642+/-0.00109; mu= 10.1998+/- 0.064 mean_var=121.6460+/-26.084, 0's: 0 Z-trim(106.7): 162 B-trim: 355 in 1/50 Lambda= 0.116285 statistics sampled from 8954 (9154) to 8954 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.651), E-opt: 0.2 (0.281), width: 16 Scan time: 2.960 The best scores are: opt bits E(32554) CCDS366.1 RBBP4 gene_id:5928|Hs108|chr1 ( 425) 2929 503.0 2.2e-142 CCDS44105.1 RBBP4 gene_id:5928|Hs108|chr1 ( 424) 2912 500.2 1.6e-141 CCDS44106.1 RBBP4 gene_id:5928|Hs108|chr1 ( 390) 2698 464.2 9.5e-131 CCDS14179.1 RBBP7 gene_id:5931|Hs108|chrX ( 425) 2640 454.5 8.7e-128 CCDS56598.1 RBBP7 gene_id:5931|Hs108|chrX ( 469) 2629 452.7 3.4e-127 >>CCDS366.1 RBBP4 gene_id:5928|Hs108|chr1 (425 aa) initn: 2929 init1: 2929 opt: 2929 Z-score: 2669.7 bits: 503.0 E(32554): 2.2e-142 Smith-Waterman score: 2929; 100.0% identity (100.0% similar) in 425 aa overlap (1-425:1-425) 10 20 30 40 50 60 pF1KB4 MADKEAAFDDAVEERVINEEYKIWKKNTPFLYDLVMTHALEWPSLTAQWLPDVTRPEGKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS36 MADKEAAFDDAVEERVINEEYKIWKKNTPFLYDLVMTHALEWPSLTAQWLPDVTRPEGKD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 FSIHRLVLGTHTSDEQNHLVIASVQLPNDDAQFDASHYDSEKGEFGGFGSVSGKIEIEIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS36 FSIHRLVLGTHTSDEQNHLVIASVQLPNDDAQFDASHYDSEKGEFGGFGSVSGKIEIEIK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 INHEGEVNRARYMPQNPCIIATKTPSSDVLVFDYTKHPSKPDPSGECNPDLRLRGHQKEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS36 INHEGEVNRARYMPQNPCIIATKTPSSDVLVFDYTKHPSKPDPSGECNPDLRLRGHQKEG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 YGLSWNPNLSGHLLSASDDHTICLWDISAVPKEGKVVDAKTIFTGHTAVVEDVSWHLLHE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS36 YGLSWNPNLSGHLLSASDDHTICLWDISAVPKEGKVVDAKTIFTGHTAVVEDVSWHLLHE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 SLFGSVADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS36 SLFGSVADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVAL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 WDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSPEDAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS36 WDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSPEDAE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB4 DGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQVWQMAENIYNDEDPEGSVDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS36 DGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQVWQMAENIYNDEDPEGSVDP 370 380 390 400 410 420 pF1KB4 EGQGS ::::: CCDS36 EGQGS >>CCDS44105.1 RBBP4 gene_id:5928|Hs108|chr1 (424 aa) initn: 2892 init1: 2892 opt: 2912 Z-score: 2654.3 bits: 500.2 E(32554): 1.6e-141 Smith-Waterman score: 2912; 99.8% identity (99.8% similar) in 425 aa overlap (1-425:1-424) 10 20 30 40 50 60 pF1KB4 MADKEAAFDDAVEERVINEEYKIWKKNTPFLYDLVMTHALEWPSLTAQWLPDVTRPEGKD :::::: ::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 MADKEA-FDDAVEERVINEEYKIWKKNTPFLYDLVMTHALEWPSLTAQWLPDVTRPEGKD 10 20 30 40 50 70 80 90 100 110 120 pF1KB4 FSIHRLVLGTHTSDEQNHLVIASVQLPNDDAQFDASHYDSEKGEFGGFGSVSGKIEIEIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 FSIHRLVLGTHTSDEQNHLVIASVQLPNDDAQFDASHYDSEKGEFGGFGSVSGKIEIEIK 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB4 INHEGEVNRARYMPQNPCIIATKTPSSDVLVFDYTKHPSKPDPSGECNPDLRLRGHQKEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 INHEGEVNRARYMPQNPCIIATKTPSSDVLVFDYTKHPSKPDPSGECNPDLRLRGHQKEG 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB4 YGLSWNPNLSGHLLSASDDHTICLWDISAVPKEGKVVDAKTIFTGHTAVVEDVSWHLLHE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 YGLSWNPNLSGHLLSASDDHTICLWDISAVPKEGKVVDAKTIFTGHTAVVEDVSWHLLHE 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB4 SLFGSVADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 SLFGSVADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVAL 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB4 WDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSPEDAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 WDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSPEDAE 300 310 320 330 340 350 370 380 390 400 410 420 pF1KB4 DGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQVWQMAENIYNDEDPEGSVDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 DGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQVWQMAENIYNDEDPEGSVDP 360 370 380 390 400 410 pF1KB4 EGQGS ::::: CCDS44 EGQGS 420 >>CCDS44106.1 RBBP4 gene_id:5928|Hs108|chr1 (390 aa) initn: 2698 init1: 2698 opt: 2698 Z-score: 2460.8 bits: 464.2 E(32554): 9.5e-131 Smith-Waterman score: 2698; 100.0% identity (100.0% similar) in 390 aa overlap (36-425:1-390) 10 20 30 40 50 60 pF1KB4 AAFDDAVEERVINEEYKIWKKNTPFLYDLVMTHALEWPSLTAQWLPDVTRPEGKDFSIHR :::::::::::::::::::::::::::::: CCDS44 MTHALEWPSLTAQWLPDVTRPEGKDFSIHR 10 20 30 70 80 90 100 110 120 pF1KB4 LVLGTHTSDEQNHLVIASVQLPNDDAQFDASHYDSEKGEFGGFGSVSGKIEIEIKINHEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 LVLGTHTSDEQNHLVIASVQLPNDDAQFDASHYDSEKGEFGGFGSVSGKIEIEIKINHEG 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB4 EVNRARYMPQNPCIIATKTPSSDVLVFDYTKHPSKPDPSGECNPDLRLRGHQKEGYGLSW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 EVNRARYMPQNPCIIATKTPSSDVLVFDYTKHPSKPDPSGECNPDLRLRGHQKEGYGLSW 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB4 NPNLSGHLLSASDDHTICLWDISAVPKEGKVVDAKTIFTGHTAVVEDVSWHLLHESLFGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 NPNLSGHLLSASDDHTICLWDISAVPKEGKVVDAKTIFTGHTAVVEDVSWHLLHESLFGS 160 170 180 190 200 210 250 260 270 280 290 300 pF1KB4 VADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 VADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRN 220 230 240 250 260 270 310 320 330 340 350 360 pF1KB4 LKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSPEDAEDGPPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 LKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSPEDAEDGPPE 280 290 300 310 320 330 370 380 390 400 410 420 pF1KB4 LLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQVWQMAENIYNDEDPEGSVDPEGQGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 LLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQVWQMAENIYNDEDPEGSVDPEGQGS 340 350 360 370 380 390 >>CCDS14179.1 RBBP7 gene_id:5931|Hs108|chrX (425 aa) initn: 2739 init1: 2592 opt: 2640 Z-score: 2407.7 bits: 454.5 E(32554): 8.7e-128 Smith-Waterman score: 2640; 89.2% identity (96.5% similar) in 426 aa overlap (1-425:1-425) 10 20 30 40 50 60 pF1KB4 MADKEAAFDDAVEERVINEEYKIWKKNTPFLYDLVMTHALEWPSLTAQWLPDVTRPEGKD ::.:: :.:.:::::::::::::::::::::::::::::.:::::.::::.::.::::: CCDS14 MASKEM-FEDTVEERVINEEYKIWKKNTPFLYDLVMTHALQWPSLTVQWLPEVTKPEGKD 10 20 30 40 50 70 80 90 100 110 120 pF1KB4 FSIHRLVLGTHTSDEQNHLVIASVQLPNDDAQFDASHYDSEKGEFGGFGSVSGKIEIEIK ...: :::::::::::::::.: :..::::::::::: ::.::::::::::.:::: ::: CCDS14 YALHWLVLGTHTSDEQNHLVVARVHIPNDDAQFDASHCDSDKGEFGGFGSVTGKIECEIK 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB4 INHEGEVNRARYMPQNPCIIATKTPSSDVLVFDYTKHPSKPDPSGECNPDLRLRGHQKEG ::::::::::::::::: ::::::::::::::::::::.::::::::::::::::::::: CCDS14 INHEGEVNRARYMPQNPHIIATKTPSSDVLVFDYTKHPAKPDPSGECNPDLRLRGHQKEG 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB4 YGLSWNPNLSGHLLSASDDHTICLWDISAVPKEGKVVDAKTIFTGHTAVVEDVSWHLLHE :::::: ::::::::::::::.:::::.: :::::.::::.:::::.::::::.:::::: CCDS14 YGLSWNSNLSGHLLSASDDHTVCLWDINAGPKEGKIVDAKAIFTGHSAVVEDVAWHLLHE 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB4 SLFGSVADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVAL ::::::::::::::::::::.:::::: :::::::::::::::::::::::::::::::: CCDS14 SLFGSVADDQKLMIWDTRSNTTSKPSHLVDAHTAEVNCLSFNPYSEFILATGSADKTVAL 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB4 WDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSPEDAE :::::::::::.:::::::::::.::::::::::::::::::::::::::::::: :::: CCDS14 WDLRNLKLKLHTFESHKDEIFQVHWSPHNETILASSGTDRRLNVWDLSKIGEEQSAEDAE 300 310 320 330 340 350 370 380 390 400 410 420 pF1KB4 DGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQVWQMAENIYNDEDPEGSVDP ::::::::::::::::::::::::::::::::::::::::.:::::::::::. . ... CCDS14 DGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQIWQMAENIYNDEESDVTTSE 360 370 380 390 400 410 pF1KB4 -EGQGS ::::: CCDS14 LEGQGS 420 >>CCDS56598.1 RBBP7 gene_id:5931|Hs108|chrX (469 aa) initn: 2739 init1: 2592 opt: 2629 Z-score: 2397.1 bits: 452.7 E(32554): 3.4e-127 Smith-Waterman score: 2629; 89.7% identity (96.9% similar) in 419 aa overlap (8-425:51-469) 10 20 30 pF1KB4 MADKEAAFDDAVEERVINEEYKIWKKNTPFLYDLVMT :.:.:::::::::::::::::::::::::: CCDS56 QACGLLLHVHLSSRLGRAAPVRTGRHLRTVFEDTVEERVINEEYKIWKKNTPFLYDLVMT 30 40 50 60 70 80 40 50 60 70 80 90 pF1KB4 HALEWPSLTAQWLPDVTRPEGKDFSIHRLVLGTHTSDEQNHLVIASVQLPNDDAQFDASH :::.:::::.::::.::.:::::...: :::::::::::::::.: :..::::::::::: CCDS56 HALQWPSLTVQWLPEVTKPEGKDYALHWLVLGTHTSDEQNHLVVARVHIPNDDAQFDASH 90 100 110 120 130 140 100 110 120 130 140 150 pF1KB4 YDSEKGEFGGFGSVSGKIEIEIKINHEGEVNRARYMPQNPCIIATKTPSSDVLVFDYTKH ::.::::::::::.:::: :::::::::::::::::::: ::::::::::::::::::: CCDS56 CDSDKGEFGGFGSVTGKIECEIKINHEGEVNRARYMPQNPHIIATKTPSSDVLVFDYTKH 150 160 170 180 190 200 160 170 180 190 200 210 pF1KB4 PSKPDPSGECNPDLRLRGHQKEGYGLSWNPNLSGHLLSASDDHTICLWDISAVPKEGKVV :.::::::::::::::::::::::::::: ::::::::::::::.:::::.: :::::.: CCDS56 PAKPDPSGECNPDLRLRGHQKEGYGLSWNSNLSGHLLSASDDHTVCLWDINAGPKEGKIV 210 220 230 240 250 260 220 230 240 250 260 270 pF1KB4 DAKTIFTGHTAVVEDVSWHLLHESLFGSVADDQKLMIWDTRSNNTSKPSHSVDAHTAEVN :::.:::::.::::::.::::::::::::::::::::::::::.:::::: ::::::::: CCDS56 DAKAIFTGHSAVVEDVAWHLLHESLFGSVADDQKLMIWDTRSNTTSKPSHLVDAHTAEVN 270 280 290 300 310 320 280 290 300 310 320 330 pF1KB4 CLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSG ::::::::::::::::::::::::::::::::::.:::::::::::.::::::::::::: CCDS56 CLSFNPYSEFILATGSADKTVALWDLRNLKLKLHTFESHKDEIFQVHWSPHNETILASSG 330 340 350 360 370 380 340 350 360 370 380 390 pF1KB4 TDRRLNVWDLSKIGEEQSPEDAEDGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDN :::::::::::::::::: ::::::::::::::::::::::::::::::::::::::::: CCDS56 TDRRLNVWDLSKIGEEQSAEDAEDGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDN 390 400 410 420 430 440 400 410 420 pF1KB4 IMQVWQMAENIYNDEDPEGSVDP-EGQGS :::.:::::::::::. . ... ::::: CCDS56 IMQIWQMAENIYNDEESDVTTSELEGQGS 450 460 425 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 22:55:09 2016 done: Fri Nov 4 22:55:09 2016 Total Scan time: 2.960 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]