FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB4277, 425 aa
1>>>pF1KB4277 425 - 425 aa - 425 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.5900+/-0.000498; mu= 11.2821+/- 0.030
mean_var=180.3872+/-40.502, 0's: 0 Z-trim(113.6): 248 B-trim: 318 in 1/48
Lambda= 0.095493
statistics sampled from 22665 (23021) to 22665 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.637), E-opt: 0.2 (0.27), width: 16
Scan time: 8.490
The best scores are: opt bits E(85289)
NP_005601 (OMIM: 602923) histone-binding protein R ( 425) 2929 416.7 5.8e-116
NP_001128727 (OMIM: 602923) histone-binding protei ( 424) 2912 414.3 2.9e-115
NP_001128728 (OMIM: 602923) histone-binding protei ( 390) 2698 384.8 2.1e-106
NP_002884 (OMIM: 300825) histone-binding protein R ( 425) 2640 376.8 5.6e-104
NP_001185648 (OMIM: 300825) histone-binding protei ( 469) 2629 375.4 1.7e-103
XP_011509771 (OMIM: 616620) PREDICTED: ribosome bi ( 285) 265 49.4 1.4e-05
NP_060726 (OMIM: 616620) ribosome biogenesis prote ( 423) 265 49.6 1.7e-05
XP_005267076 (OMIM: 215100,266500,601757,614879) P ( 285) 251 47.5 5.2e-05
NP_000279 (OMIM: 215100,266500,601757,614879) pero ( 323) 251 47.6 5.6e-05
NP_003301 (OMIM: 608998) protein TSSC1 isoform 2 [ ( 387) 242 46.4 0.00015
NP_001308124 (OMIM: 270710,602342,608628,616944) F ( 427) 239 46.1 0.00021
NP_113673 (OMIM: 610597) glutamate-rich WD repeat- ( 446) 239 46.1 0.00022
NP_001308122 (OMIM: 270710,602342,608628,616944) F ( 514) 239 46.2 0.00024
XP_011511443 (OMIM: 270710,602342,608628,616944) P ( 514) 239 46.2 0.00024
XP_006713809 (OMIM: 270710,602342,608628,616944) P ( 514) 239 46.2 0.00024
XP_011511444 (OMIM: 270710,602342,608628,616944) P ( 514) 239 46.2 0.00024
XP_011511445 (OMIM: 270710,602342,608628,616944) P ( 514) 239 46.2 0.00024
NP_078941 (OMIM: 270710,602342,608628,616944) F-bo ( 514) 239 46.2 0.00024
XP_016862674 (OMIM: 270710,602342,608628,616944) P ( 514) 239 46.2 0.00024
XP_005247832 (OMIM: 270710,602342,608628,616944) P ( 514) 239 46.2 0.00024
NP_001308123 (OMIM: 270710,602342,608628,616944) F ( 514) 239 46.2 0.00024
NP_001177386 (OMIM: 605002) coronin-2B isoform 2 [ ( 475) 235 45.6 0.00033
NP_001310944 (OMIM: 605002) coronin-2B isoform 2 [ ( 475) 235 45.6 0.00033
NP_001310943 (OMIM: 605002) coronin-2B isoform 2 [ ( 475) 235 45.6 0.00033
NP_001177385 (OMIM: 605002) coronin-2B isoform 2 [ ( 475) 235 45.6 0.00033
NP_006082 (OMIM: 605002) coronin-2B isoform 1 [Hom ( 480) 235 45.6 0.00033
NP_942590 (OMIM: 608141) nucleoporin Nup43 [Homo s ( 380) 232 45.0 0.00038
NP_003380 (OMIM: 602159) coronin-2A [Homo sapiens] ( 525) 233 45.3 0.00042
NP_438171 (OMIM: 602159) coronin-2A [Homo sapiens] ( 525) 233 45.3 0.00042
XP_011517288 (OMIM: 602159) PREDICTED: coronin-2A ( 525) 233 45.3 0.00042
XP_005267019 (OMIM: 608141) PREDICTED: nucleoporin ( 313) 227 44.2 0.00054
XP_011534101 (OMIM: 608141) PREDICTED: nucleoporin ( 317) 227 44.3 0.00055
XP_005267018 (OMIM: 608141) PREDICTED: nucleoporin ( 333) 227 44.3 0.00057
XP_005267017 (OMIM: 608141) PREDICTED: nucleoporin ( 333) 227 44.3 0.00057
XP_011534100 (OMIM: 608141) PREDICTED: nucleoporin ( 347) 227 44.3 0.00058
NP_599020 (OMIM: 400033) F-box-like/WD repeat-cont ( 522) 229 44.8 0.00062
NP_150600 (OMIM: 400033) F-box-like/WD repeat-cont ( 522) 229 44.8 0.00062
NP_599021 (OMIM: 400033) F-box-like/WD repeat-cont ( 522) 229 44.8 0.00062
XP_005262629 (OMIM: 400033) PREDICTED: F-box-like/ ( 536) 229 44.8 0.00063
XP_016885576 (OMIM: 400033) PREDICTED: F-box-like/ ( 540) 229 44.8 0.00063
XP_016885575 (OMIM: 400033) PREDICTED: F-box-like/ ( 577) 229 44.8 0.00066
NP_006089 (OMIM: 176981) receptor of activated pro ( 317) 224 43.8 0.00073
XP_016857569 (OMIM: 608067) PREDICTED: E3 ubiquiti ( 455) 226 44.3 0.00076
XP_016857567 (OMIM: 608067) PREDICTED: E3 ubiquiti ( 455) 226 44.3 0.00076
XP_016857568 (OMIM: 608067) PREDICTED: E3 ubiquiti ( 455) 226 44.3 0.00076
XP_016857566 (OMIM: 608067) PREDICTED: E3 ubiquiti ( 477) 226 44.3 0.00078
NP_001273573 (OMIM: 608067) E3 ubiquitin-protein l ( 491) 226 44.3 0.00079
XP_016857565 (OMIM: 608067) PREDICTED: E3 ubiquiti ( 491) 226 44.3 0.00079
XP_016857564 (OMIM: 608067) PREDICTED: E3 ubiquiti ( 497) 226 44.4 0.0008
XP_016857563 (OMIM: 608067) PREDICTED: E3 ubiquiti ( 507) 226 44.4 0.00081
>>NP_005601 (OMIM: 602923) histone-binding protein RBBP4 (425 aa)
initn: 2929 init1: 2929 opt: 2929 Z-score: 2202.9 bits: 416.7 E(85289): 5.8e-116
Smith-Waterman score: 2929; 100.0% identity (100.0% similar) in 425 aa overlap (1-425:1-425)
10 20 30 40 50 60
pF1KB4 MADKEAAFDDAVEERVINEEYKIWKKNTPFLYDLVMTHALEWPSLTAQWLPDVTRPEGKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MADKEAAFDDAVEERVINEEYKIWKKNTPFLYDLVMTHALEWPSLTAQWLPDVTRPEGKD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 FSIHRLVLGTHTSDEQNHLVIASVQLPNDDAQFDASHYDSEKGEFGGFGSVSGKIEIEIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 FSIHRLVLGTHTSDEQNHLVIASVQLPNDDAQFDASHYDSEKGEFGGFGSVSGKIEIEIK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 INHEGEVNRARYMPQNPCIIATKTPSSDVLVFDYTKHPSKPDPSGECNPDLRLRGHQKEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 INHEGEVNRARYMPQNPCIIATKTPSSDVLVFDYTKHPSKPDPSGECNPDLRLRGHQKEG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 YGLSWNPNLSGHLLSASDDHTICLWDISAVPKEGKVVDAKTIFTGHTAVVEDVSWHLLHE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 YGLSWNPNLSGHLLSASDDHTICLWDISAVPKEGKVVDAKTIFTGHTAVVEDVSWHLLHE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 SLFGSVADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 SLFGSVADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVAL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 WDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSPEDAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 WDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSPEDAE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 DGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQVWQMAENIYNDEDPEGSVDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 DGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQVWQMAENIYNDEDPEGSVDP
370 380 390 400 410 420
pF1KB4 EGQGS
:::::
NP_005 EGQGS
>>NP_001128727 (OMIM: 602923) histone-binding protein RB (424 aa)
initn: 2892 init1: 2892 opt: 2912 Z-score: 2190.3 bits: 414.3 E(85289): 2.9e-115
Smith-Waterman score: 2912; 99.8% identity (99.8% similar) in 425 aa overlap (1-425:1-424)
10 20 30 40 50 60
pF1KB4 MADKEAAFDDAVEERVINEEYKIWKKNTPFLYDLVMTHALEWPSLTAQWLPDVTRPEGKD
:::::: :::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MADKEA-FDDAVEERVINEEYKIWKKNTPFLYDLVMTHALEWPSLTAQWLPDVTRPEGKD
10 20 30 40 50
70 80 90 100 110 120
pF1KB4 FSIHRLVLGTHTSDEQNHLVIASVQLPNDDAQFDASHYDSEKGEFGGFGSVSGKIEIEIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FSIHRLVLGTHTSDEQNHLVIASVQLPNDDAQFDASHYDSEKGEFGGFGSVSGKIEIEIK
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB4 INHEGEVNRARYMPQNPCIIATKTPSSDVLVFDYTKHPSKPDPSGECNPDLRLRGHQKEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 INHEGEVNRARYMPQNPCIIATKTPSSDVLVFDYTKHPSKPDPSGECNPDLRLRGHQKEG
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB4 YGLSWNPNLSGHLLSASDDHTICLWDISAVPKEGKVVDAKTIFTGHTAVVEDVSWHLLHE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YGLSWNPNLSGHLLSASDDHTICLWDISAVPKEGKVVDAKTIFTGHTAVVEDVSWHLLHE
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB4 SLFGSVADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLFGSVADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVAL
240 250 260 270 280 290
310 320 330 340 350 360
pF1KB4 WDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSPEDAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSPEDAE
300 310 320 330 340 350
370 380 390 400 410 420
pF1KB4 DGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQVWQMAENIYNDEDPEGSVDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQVWQMAENIYNDEDPEGSVDP
360 370 380 390 400 410
pF1KB4 EGQGS
:::::
NP_001 EGQGS
420
>>NP_001128728 (OMIM: 602923) histone-binding protein RB (390 aa)
initn: 2698 init1: 2698 opt: 2698 Z-score: 2031.3 bits: 384.8 E(85289): 2.1e-106
Smith-Waterman score: 2698; 100.0% identity (100.0% similar) in 390 aa overlap (36-425:1-390)
10 20 30 40 50 60
pF1KB4 AAFDDAVEERVINEEYKIWKKNTPFLYDLVMTHALEWPSLTAQWLPDVTRPEGKDFSIHR
::::::::::::::::::::::::::::::
NP_001 MTHALEWPSLTAQWLPDVTRPEGKDFSIHR
10 20 30
70 80 90 100 110 120
pF1KB4 LVLGTHTSDEQNHLVIASVQLPNDDAQFDASHYDSEKGEFGGFGSVSGKIEIEIKINHEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LVLGTHTSDEQNHLVIASVQLPNDDAQFDASHYDSEKGEFGGFGSVSGKIEIEIKINHEG
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB4 EVNRARYMPQNPCIIATKTPSSDVLVFDYTKHPSKPDPSGECNPDLRLRGHQKEGYGLSW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EVNRARYMPQNPCIIATKTPSSDVLVFDYTKHPSKPDPSGECNPDLRLRGHQKEGYGLSW
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB4 NPNLSGHLLSASDDHTICLWDISAVPKEGKVVDAKTIFTGHTAVVEDVSWHLLHESLFGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NPNLSGHLLSASDDHTICLWDISAVPKEGKVVDAKTIFTGHTAVVEDVSWHLLHESLFGS
160 170 180 190 200 210
250 260 270 280 290 300
pF1KB4 VADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRN
220 230 240 250 260 270
310 320 330 340 350 360
pF1KB4 LKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSPEDAEDGPPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSPEDAEDGPPE
280 290 300 310 320 330
370 380 390 400 410 420
pF1KB4 LLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQVWQMAENIYNDEDPEGSVDPEGQGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQVWQMAENIYNDEDPEGSVDPEGQGS
340 350 360 370 380 390
>>NP_002884 (OMIM: 300825) histone-binding protein RBBP7 (425 aa)
initn: 2739 init1: 2592 opt: 2640 Z-score: 1987.7 bits: 376.8 E(85289): 5.6e-104
Smith-Waterman score: 2640; 89.2% identity (96.5% similar) in 426 aa overlap (1-425:1-425)
10 20 30 40 50 60
pF1KB4 MADKEAAFDDAVEERVINEEYKIWKKNTPFLYDLVMTHALEWPSLTAQWLPDVTRPEGKD
::.:: :.:.:::::::::::::::::::::::::::::.:::::.::::.::.:::::
NP_002 MASKEM-FEDTVEERVINEEYKIWKKNTPFLYDLVMTHALQWPSLTVQWLPEVTKPEGKD
10 20 30 40 50
70 80 90 100 110 120
pF1KB4 FSIHRLVLGTHTSDEQNHLVIASVQLPNDDAQFDASHYDSEKGEFGGFGSVSGKIEIEIK
...: :::::::::::::::.: :..::::::::::: ::.::::::::::.:::: :::
NP_002 YALHWLVLGTHTSDEQNHLVVARVHIPNDDAQFDASHCDSDKGEFGGFGSVTGKIECEIK
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB4 INHEGEVNRARYMPQNPCIIATKTPSSDVLVFDYTKHPSKPDPSGECNPDLRLRGHQKEG
::::::::::::::::: ::::::::::::::::::::.:::::::::::::::::::::
NP_002 INHEGEVNRARYMPQNPHIIATKTPSSDVLVFDYTKHPAKPDPSGECNPDLRLRGHQKEG
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB4 YGLSWNPNLSGHLLSASDDHTICLWDISAVPKEGKVVDAKTIFTGHTAVVEDVSWHLLHE
:::::: ::::::::::::::.:::::.: :::::.::::.:::::.::::::.::::::
NP_002 YGLSWNSNLSGHLLSASDDHTVCLWDINAGPKEGKIVDAKAIFTGHSAVVEDVAWHLLHE
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB4 SLFGSVADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVAL
::::::::::::::::::::.:::::: ::::::::::::::::::::::::::::::::
NP_002 SLFGSVADDQKLMIWDTRSNTTSKPSHLVDAHTAEVNCLSFNPYSEFILATGSADKTVAL
240 250 260 270 280 290
310 320 330 340 350 360
pF1KB4 WDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSPEDAE
:::::::::::.:::::::::::.::::::::::::::::::::::::::::::: ::::
NP_002 WDLRNLKLKLHTFESHKDEIFQVHWSPHNETILASSGTDRRLNVWDLSKIGEEQSAEDAE
300 310 320 330 340 350
370 380 390 400 410 420
pF1KB4 DGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQVWQMAENIYNDEDPEGSVDP
::::::::::::::::::::::::::::::::::::::::.:::::::::::. . ...
NP_002 DGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQIWQMAENIYNDEESDVTTSE
360 370 380 390 400 410
pF1KB4 -EGQGS
:::::
NP_002 LEGQGS
420
>>NP_001185648 (OMIM: 300825) histone-binding protein RB (469 aa)
initn: 2739 init1: 2592 opt: 2629 Z-score: 1979.1 bits: 375.4 E(85289): 1.7e-103
Smith-Waterman score: 2629; 89.7% identity (96.9% similar) in 419 aa overlap (8-425:51-469)
10 20 30
pF1KB4 MADKEAAFDDAVEERVINEEYKIWKKNTPFLYDLVMT
:.:.::::::::::::::::::::::::::
NP_001 QACGLLLHVHLSSRLGRAAPVRTGRHLRTVFEDTVEERVINEEYKIWKKNTPFLYDLVMT
30 40 50 60 70 80
40 50 60 70 80 90
pF1KB4 HALEWPSLTAQWLPDVTRPEGKDFSIHRLVLGTHTSDEQNHLVIASVQLPNDDAQFDASH
:::.:::::.::::.::.:::::...: :::::::::::::::.: :..:::::::::::
NP_001 HALQWPSLTVQWLPEVTKPEGKDYALHWLVLGTHTSDEQNHLVVARVHIPNDDAQFDASH
90 100 110 120 130 140
100 110 120 130 140 150
pF1KB4 YDSEKGEFGGFGSVSGKIEIEIKINHEGEVNRARYMPQNPCIIATKTPSSDVLVFDYTKH
::.::::::::::.:::: :::::::::::::::::::: :::::::::::::::::::
NP_001 CDSDKGEFGGFGSVTGKIECEIKINHEGEVNRARYMPQNPHIIATKTPSSDVLVFDYTKH
150 160 170 180 190 200
160 170 180 190 200 210
pF1KB4 PSKPDPSGECNPDLRLRGHQKEGYGLSWNPNLSGHLLSASDDHTICLWDISAVPKEGKVV
:.::::::::::::::::::::::::::: ::::::::::::::.:::::.: :::::.:
NP_001 PAKPDPSGECNPDLRLRGHQKEGYGLSWNSNLSGHLLSASDDHTVCLWDINAGPKEGKIV
210 220 230 240 250 260
220 230 240 250 260 270
pF1KB4 DAKTIFTGHTAVVEDVSWHLLHESLFGSVADDQKLMIWDTRSNNTSKPSHSVDAHTAEVN
:::.:::::.::::::.::::::::::::::::::::::::::.:::::: :::::::::
NP_001 DAKAIFTGHSAVVEDVAWHLLHESLFGSVADDQKLMIWDTRSNTTSKPSHLVDAHTAEVN
270 280 290 300 310 320
280 290 300 310 320 330
pF1KB4 CLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSG
::::::::::::::::::::::::::::::::::.:::::::::::.:::::::::::::
NP_001 CLSFNPYSEFILATGSADKTVALWDLRNLKLKLHTFESHKDEIFQVHWSPHNETILASSG
330 340 350 360 370 380
340 350 360 370 380 390
pF1KB4 TDRRLNVWDLSKIGEEQSPEDAEDGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDN
:::::::::::::::::: :::::::::::::::::::::::::::::::::::::::::
NP_001 TDRRLNVWDLSKIGEEQSAEDAEDGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDN
390 400 410 420 430 440
400 410 420
pF1KB4 IMQVWQMAENIYNDEDPEGSVDP-EGQGS
:::.:::::::::::. . ... :::::
NP_001 IMQIWQMAENIYNDEESDVTTSELEGQGS
450 460
>>XP_011509771 (OMIM: 616620) PREDICTED: ribosome biogen (285 aa)
initn: 370 init1: 195 opt: 265 Z-score: 221.4 bits: 49.4 E(85289): 1.4e-05
Smith-Waterman score: 278; 31.6% identity (64.4% similar) in 174 aa overlap (169-342:111-271)
140 150 160 170 180 190
pF1KB4 IIATKTPSSDVLVFDYTKHPSKPDPSGECNPDLRLRGHQKEGYGLSWNPNLSGHLLSASD
: . : ::.. .. :. . .. :::
XP_011 VPTDEEDEMEESTNRPRKKQKTEQLGLTRTPIVTLSGHMEAVSSVLWSD--AEEICSASW
90 100 110 120 130
200 210 220 230 240 250
pF1KB4 DHTICLWDISAVPKEGKVVDAKTIFTGHTAVVEDVSWHLLHESLFGSVADDQKLMIWDTR
:::: .::. . :.. :. .::. : . .:. : . : .: . :... .:: :
XP_011 DHTIRVWDV----ESGSL---KSTLTGNK-VFNCISYSPLCKRL-ASGSTDRHIRLWDPR
140 150 160 170 180
260 270 280 290 300 310
pF1KB4 SNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSFESHKD
... : : :. .::. :. ....: : : .:: :. : ::: :. : :... .:.:
XP_011 TKDGSLVSLSLTSHTGWVTSVKWSPTHEQQLISGSLDNIVKLWDTRSCKAPLYDLAAHED
190 200 210 220 230 240
320 330 340 350 360 370
pF1KB4 EIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSPEDAEDGPPELLFIHGGHTAKIS
....:.:. . .: :.:.: .:
XP_011 KVLSVDWT--DTGLLLSGGADNKLYSYRYSPTTSHVGA
250 260 270 280
>>NP_060726 (OMIM: 616620) ribosome biogenesis protein W (423 aa)
initn: 370 init1: 195 opt: 265 Z-score: 219.4 bits: 49.6 E(85289): 1.7e-05
Smith-Waterman score: 278; 31.6% identity (64.4% similar) in 174 aa overlap (169-342:249-409)
140 150 160 170 180 190
pF1KB4 IIATKTPSSDVLVFDYTKHPSKPDPSGECNPDLRLRGHQKEGYGLSWNPNLSGHLLSASD
: . : ::.. .. :. . .. :::
NP_060 VPTDEEDEMEESTNRPRKKQKTEQLGLTRTPIVTLSGHMEAVSSVLWSD--AEEICSASW
220 230 240 250 260 270
200 210 220 230 240 250
pF1KB4 DHTICLWDISAVPKEGKVVDAKTIFTGHTAVVEDVSWHLLHESLFGSVADDQKLMIWDTR
:::: .::. . :.. :. .::. : . .:. : . : .: . :... .:: :
NP_060 DHTIRVWDV----ESGSL---KSTLTGNK-VFNCISYSPLCKRL-ASGSTDRHIRLWDPR
280 290 300 310 320
260 270 280 290 300 310
pF1KB4 SNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSFESHKD
... : : :. .::. :. ....: : : .:: :. : ::: :. : :... .:.:
NP_060 TKDGSLVSLSLTSHTGWVTSVKWSPTHEQQLISGSLDNIVKLWDTRSCKAPLYDLAAHED
330 340 350 360 370 380
320 330 340 350 360 370
pF1KB4 EIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSPEDAEDGPPELLFIHGGHTAKIS
....:.:. . .: :.:.: .:
NP_060 KVLSVDWT--DTGLLLSGGADNKLYSYRYSPTTSHVGA
390 400 410 420
>>XP_005267076 (OMIM: 215100,266500,601757,614879) PREDI (285 aa)
initn: 361 init1: 177 opt: 251 Z-score: 211.0 bits: 47.5 E(85289): 5.2e-05
Smith-Waterman score: 306; 26.5% identity (54.7% similar) in 245 aa overlap (162-405:58-279)
140 150 160 170 180 190
pF1KB4 YMPQNPCIIATKTPSSDVLVFDYTKHPSKPDPSGECNPDLRLRGHQKEGYGLSWNPNLSG
: . .: . : .: :...:. . .
XP_005 WNDGLFDVTWSENNEHVLITCSGDGSLQLWDTAKAAGPLQVYKEHAQEVYSVDWSQTRGE
30 40 50 60 70 80
200 210 220 230 240 250
pF1KB4 HLL-SASDDHTICLWDISAVPKEGKVVDAKTIFTGHTAVVEDVSWHLLHESLFGSVADDQ
.:. :.: :.:. ::: : :: . : :: ... .. : . :.:.. ::
XP_005 QLVVSGSWDQTVKLWD----PTVGKSL---CTFRGHESIIYSTIWSPHIPGCFASASGDQ
90 100 110 120 130 140
260 270 280 290 300 310
pF1KB4 KLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKL
: :::... .. . :: ::. .. :.: .:.::..: .. :::::.. .
XP_005 TLRIWDVKAAGVRI---VIPAHQAEILSCDWCKYNENLLVTGAVDCSLRGWDLRNVRQPV
150 160 170 180 190
320 330 340 350 360 370
pF1KB4 HSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSPEDAEDGPPELLFIH
. .: : .:..:: . ..::: . : . :..:: : ::
XP_005 FELLGHTYAIRRVKFSPFHASVLASCSYDFTVRFWNFSK-------------PDSLLETV
200 210 220 230 240
380 390 400 410 420
pF1KB4 GGHTAKISDFSWNPNEPWVICSVSEDNIMQVWQMAENIYNDEDPEGSVDPEGQGS
:: .... . : . . : :. ..... :
XP_005 EHHTEFTCGLDFSLQSPTQVADCSWDETIKIYDPACLTIPA
250 260 270 280
>>NP_000279 (OMIM: 215100,266500,601757,614879) peroxiso (323 aa)
initn: 361 init1: 177 opt: 251 Z-score: 210.3 bits: 47.6 E(85289): 5.6e-05
Smith-Waterman score: 306; 26.5% identity (54.7% similar) in 245 aa overlap (162-405:96-317)
140 150 160 170 180 190
pF1KB4 YMPQNPCIIATKTPSSDVLVFDYTKHPSKPDPSGECNPDLRLRGHQKEGYGLSWNPNLSG
: . .: . : .: :...:. . .
NP_000 WNDGLFDVTWSENNEHVLITCSGDGSLQLWDTAKAAGPLQVYKEHAQEVYSVDWSQTRGE
70 80 90 100 110 120
200 210 220 230 240 250
pF1KB4 HLL-SASDDHTICLWDISAVPKEGKVVDAKTIFTGHTAVVEDVSWHLLHESLFGSVADDQ
.:. :.: :.:. ::: : :: . : :: ... .. : . :.:.. ::
NP_000 QLVVSGSWDQTVKLWD----PTVGKSL---CTFRGHESIIYSTIWSPHIPGCFASASGDQ
130 140 150 160 170
260 270 280 290 300 310
pF1KB4 KLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKL
: :::... .. . :: ::. .. :.: .:.::..: .. :::::.. .
NP_000 TLRIWDVKAAGVRI---VIPAHQAEILSCDWCKYNENLLVTGAVDCSLRGWDLRNVRQPV
180 190 200 210 220 230
320 330 340 350 360 370
pF1KB4 HSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSPEDAEDGPPELLFIH
. .: : .:..:: . ..::: . : . :..:: : ::
NP_000 FELLGHTYAIRRVKFSPFHASVLASCSYDFTVRFWNFSK-------------PDSLLETV
240 250 260 270 280
380 390 400 410 420
pF1KB4 GGHTAKISDFSWNPNEPWVICSVSEDNIMQVWQMAENIYNDEDPEGSVDPEGQGS
:: .... . : . . : :. ..... :
NP_000 EHHTEFTCGLDFSLQSPTQVADCSWDETIKIYDPACLTIPA
290 300 310 320
>>NP_003301 (OMIM: 608998) protein TSSC1 isoform 2 [Homo (387 aa)
initn: 240 init1: 95 opt: 242 Z-score: 202.8 bits: 46.4 E(85289): 0.00015
Smith-Waterman score: 266; 22.3% identity (51.3% similar) in 376 aa overlap (58-396:10-369)
30 40 50 60 70 80
pF1KB4 TPFLYDLVMTHALEWPSLTAQWLPDVTRPEGKDFSIHRLVLGTHTSDEQNHLVIASVQLP
: .:. . :. : .: :: ..:
NP_003 MEDDAPVIYGLEFQARALTPQTAETDAIRFLV--GTQSL
10 20 30
90 100 110 120 130 140
pF1KB4 NDDAQFDASHYDSEKGEFGGFGSVSGKIEIEIKINHEGEVNRARYMPQNPCIIAT---KT
. : :. .:.: .. :. .. ... ::. . : . ...: .:
NP_003 KYDNQIHIIDFDDE----------NNIINKNVLLHQAGEIWHISASPADRGVLTTCYNRT
40 50 60 70 80
150 160 170 180
pF1KB4 PSSDVLV----------FDYTKHPSKPDPSGECNPDLRLRGH-QKEGYG----LSWNPNL
.: ::. .. .: : :: :. :.: : .. ..: . :.:
NP_003 SDSKVLTCAAVWRMPKELESGSHES-PDDSSSTAQTLELLCHLDNTAHGNMACVVWEPMG
90 100 110 120 130 140
190 200 210 220 230 240
pF1KB4 SGH-LLSASDDHTICLWDISAVPKEGKVVDAKTIFTGHTAVVEDVSWHLLHESLFGSVAD
.:. ..: .:.: : :::.. ... .... .. . : :. ..:.
NP_003 DGKKIISLADNH-ILLWDLQESSSQAVLASSASLEGKGQLKFTSGRWSPHHNCTQVATAN
150 160 170 180 190 200
250 260 270 280 290 300
pF1KB4 DQKLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKL
: : ::::: :. .:: : :.::: ... ::. . : : .:: ::.
NP_003 DTTLRGWDTRS--MSQIYCIENAHGQLVRDLDFNPNKQYYLASCGDDCKVKFWDTRNVTE
210 220 230 240 250 260
310 320 330 340 350 360
pF1KB4 KLHSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEE--------QSPEDAE
....: :. ...:... .. .. ....: :. . .. .:. : .. : :
NP_003 PVKTLEEHSHWVWNVRYNHSHDQLVLTGSSDSRVILSNMVSISSEPFGHLVDDDDISDQE
270 280 290 300 310 320
370 380 390 400 410
pF1KB4 DGPPE----------LLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQVWQMAENIYN
: : .. . : .. .:. .::.. :.: :
NP_003 DHRSEEKSKEPLQDNVIATYEEHEDSVYAVDWSSADPWLFASLSYDGRLVINRVPRALKY
330 340 350 360 370 380
420
pF1KB4 DEDPEGSVDPEGQGS
NP_003 HILL
425 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 22:55:10 2016 done: Fri Nov 4 22:55:11 2016
Total Scan time: 8.490 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]