FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB4278, 344 aa 1>>>pF1KB4278 344 - 344 aa - 344 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.2810+/-0.00082; mu= 16.5494+/- 0.050 mean_var=66.4917+/-13.450, 0's: 0 Z-trim(106.8): 25 B-trim: 472 in 1/49 Lambda= 0.157286 statistics sampled from 9186 (9210) to 9186 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.661), E-opt: 0.2 (0.283), width: 16 Scan time: 2.770 The best scores are: opt bits E(32554) CCDS3581.1 CCNG2 gene_id:901|Hs108|chr4 ( 344) 2294 529.3 1.8e-150 CCDS4360.1 CCNG1 gene_id:900|Hs108|chr5 ( 295) 972 229.3 3.2e-60 CCDS3580.1 CCNI gene_id:10983|Hs108|chr4 ( 377) 417 103.4 3.2e-22 CCDS34236.1 CCNI2 gene_id:645121|Hs108|chr5 ( 369) 298 76.4 4.2e-14 >>CCDS3581.1 CCNG2 gene_id:901|Hs108|chr4 (344 aa) initn: 2294 init1: 2294 opt: 2294 Z-score: 2815.0 bits: 529.3 E(32554): 1.8e-150 Smith-Waterman score: 2294; 100.0% identity (100.0% similar) in 344 aa overlap (1-344:1-344) 10 20 30 40 50 60 pF1KB4 MKDLGAEHLAGHEGVQLLGLLNVYLEQEERFQPREKGLSLIEATPENDNTLCPGLRNAKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS35 MKDLGAEHLAGHEGVQLLGLLNVYLEQEERFQPREKGLSLIEATPENDNTLCPGLRNAKV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 EDLRSLANFFGSCTETFVLAVNILDRFLALMKVKPKHLSCIGVCSFLLAARIVEEDCNIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS35 EDLRSLANFFGSCTETFVLAVNILDRFLALMKVKPKHLSCIGVCSFLLAARIVEEDCNIP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 STHDVIRISQCKCTASDIKRMEKIISEKLHYELEATTALNFLHLYHTIILCHTSERKEIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS35 STHDVIRISQCKCTASDIKRMEKIISEKLHYELEATTALNFLHLYHTIILCHTSERKEIL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 SLDKLEAQLKACNCRLIFSKAKPSVLALCLLNLEVETLKSVELLEILLLVKKHSKINDTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS35 SLDKLEAQLKACNCRLIFSKAKPSVLALCLLNLEVETLKSVELLEILLLVKKHSKINDTE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 FFYWRELVSKCLAEYSSPECCKPDLKKLVWIVSRRTAQNLHNSYYSVPELPTIPEGGCFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS35 FFYWRELVSKCLAEYSSPECCKPDLKKLVWIVSRRTAQNLHNSYYSVPELPTIPEGGCFD 250 260 270 280 290 300 310 320 330 340 pF1KB4 ESESEDSCEDMSCGEESLSSSPPSDQECTFFFNFKVAQTLCFPS :::::::::::::::::::::::::::::::::::::::::::: CCDS35 ESESEDSCEDMSCGEESLSSSPPSDQECTFFFNFKVAQTLCFPS 310 320 330 340 >>CCDS4360.1 CCNG1 gene_id:900|Hs108|chr5 (295 aa) initn: 972 init1: 498 opt: 972 Z-score: 1194.7 bits: 229.3 E(32554): 3.2e-60 Smith-Waterman score: 972; 52.8% identity (79.3% similar) in 290 aa overlap (7-295:3-292) 10 20 30 40 50 60 pF1KB4 MKDLGAEHLAGHEGVQLLGLLNVYLEQEERFQPREKGLSLIEATPENDNTLCPGLRNAKV : :. .. .:: ::. :::: : ::. :: :::.. .: . ::. .: CCDS43 MIEVLTTTDSQKLLHQLNALLEQESRCQPKVCGLRLIESAHDNGLRMTARLRDFEV 10 20 30 40 50 70 80 90 100 110 120 pF1KB4 EDLRSLANFFGSCTETFVLAVNILDRFLALMKVKPKHLSCIGVCSFLLAARIVEEDCNIP .:: ::..::: :::: ::::.:::::. :::.::::.:.:. : ::.. .::. :.: CCDS43 KDLLSLTQFFGFDTETFSLAVNLLDRFLSKMKVQPKHLGCVGLSCFYLAVKSIEEERNVP 60 70 80 90 100 110 130 140 150 160 170 pF1KB4 STHDVIRISQCKCTASDIKRMEKIISEKLHYELEATTALNFLHLYHTIILCHTS-ERKEI . :.::::: . :.::. :::::. ::. ....::::..::.::.... . ::.. CCDS43 LATDLIRISQYRFTVSDLMRMEKIVLEKVCWKVKATTAFQFLQLYYSLLQENLPLERRNS 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB4 LSLDKLEAQLKACNCRLIFSKAKPSVLALCLLNLEVETLKSVELLEILLLVKKHSKINDT .....::::::::.::.:::::::::::: .. ::... : ::: : . ..:::::: CCDS43 INFERLEAQLKACHCRIIFSKAKPSVLALSIIALEIQAQKCVELTEGIECLQKHSKINGR 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB4 EFFYWRELVSKCLAEYSSPECCKPDLKKLVWIVSRRTAQNLHNSYYSVPELPTIPEGGCF .. .:.:::::::.:::: .: ::...:: :::: :::..:..::: . .:::::: CCDS43 DLTFWQELVSKCLTEYSSNKCSKPNVQKLKWIVSGRTARQLKHSYYRITHLPTIPEMVP 240 250 260 270 280 290 300 310 320 330 340 pF1KB4 DESESEDSCEDMSCGEESLSSSPPSDQECTFFFNFKVAQTLCFPS >>CCDS3580.1 CCNI gene_id:10983|Hs108|chr4 (377 aa) initn: 362 init1: 325 opt: 417 Z-score: 512.5 bits: 103.4 E(32554): 3.2e-22 Smith-Waterman score: 417; 36.4% identity (67.1% similar) in 228 aa overlap (41-257:31-252) 20 30 40 50 60 70 pF1KB4 GHEGVQLLGLLNVYLEQEERFQPREKGLSLIEATPENDNTLCPGLRNAKVEDLRSLANFF .. : :.: . :. :. .. : .: : CCDS35 MKFPGPLENQRLSFLLEKAITREAQMWKVNVRKMPSNQN-VSPSQRDEVIQWLAKLKYQF 10 20 30 40 50 80 90 100 110 120 130 pF1KB4 GSCTETFVLAVNILDRFLALMKVKPKHLSCIGVCSFLLAARIVEEDCNIPSTHDVIRISQ . :::.:: ..:::::: .:..::.::::.. :.:::. :::: :: . . : : CCDS35 NLYPETFALASSLLDRFLATVKAHPKYLSCIAISCFFLAAKTVEEDERIPVLKVLARDSF 60 70 80 90 100 110 140 150 160 170 180 pF1KB4 CKCTASDIKRMEKIISEKLHYELEATTALNFLHLYHTIILCHTSERKEIL-SLDKLEA-- : :..:.: :::.:: .::...:...: :.:::..:.: . : : ..: :: :: CCDS35 CGCSSSEILRMERIILDKLNWDLHTATPLDFLHIFHAIAV---STRPQLLFSLPKLSPSQ 120 130 140 150 160 170 190 200 210 220 230 pF1KB4 -------QLKAC-NCRLIFSKAKPSVLALCLLNLEVETLKSVELLEILLLVKKHSKINDT :: : : .. . . :.::: ...::.: : . : . . . ........ CCDS35 HLAVLTKQLLHCMACNQLL-QFRGSMLALAMVSLEMEKLIP-DWLSLTIELLQKAQMDSS 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB4 EFFYWRELVSKCLAEYSSPECCKPDLKKLVWIVSRRTAQNLHNSYYSVPELPTIPEGGCF .... ::::.. :. .: CCDS35 QLIHCRELVAHHLSTLQSSLPLNSVYVYRPLKHTLVTCDKGVFRLHPSSVPGPDFSKDNS 240 250 260 270 280 290 >>CCDS34236.1 CCNI2 gene_id:645121|Hs108|chr5 (369 aa) initn: 288 init1: 207 opt: 298 Z-score: 366.7 bits: 76.4 E(32554): 4.2e-14 Smith-Waterman score: 298; 30.9% identity (58.7% similar) in 223 aa overlap (45-260:142-360) 20 30 40 50 60 70 pF1KB4 VQLLGLLNVYLEQEERFQPREKGLSLIEATPENDNTLCPGLRNAKVEDLRSLANFFGSCT :... .: ..... . :: : : : CCDS34 NLEGDLDERRLLCHLQLAQDREARLWRGGKPQDE--ICDAFEEVVLWLLR-LQNTFYFSQ 120 130 140 150 160 80 90 100 110 120 130 pF1KB4 ETFVLAVNILDRFLALMKVKPKHLSCIGVCSFLLAARIVEEDCNIPSTHDVIRISQCKCT :: ::..:. :.: .::: :.: : . :. :::.. ::. ::...: . . CCDS34 STFNLALTIFGRLLISVKVKEKYLHCATITSLRLAAKVNEEEEFIPQVKDFTKHYGSDYS 170 180 190 200 210 220 140 150 160 170 180 pF1KB4 ASDIKRMEKIISEKLHYELEATTALNFLHLYHTIILC---HTSE----RKEILSLDKLEA ... ::: : ..::..: : :.:: ..:.... :. : :. : . .: CCDS34 PNELLRMELAILDRLHWDLYIGTPLDFLTIFHALVVLSWPHVLELLPQRNPSLHVASLTR 230 240 250 260 270 280 190 200 210 220 230 240 pF1KB4 QLKACNCRLIFSKAKPSVLALCLLNLEVETLKSVELLEILLLVKKHSKINDTEFFYWREL ::. : . . : :.::: ...::.: : : :.:: ....: .. .:: CCDS34 QLQHCMAGHQLLQFKGSTLALVIITLELERLMPGWCAPISDLLKK-AQVGDMQYSCCKEL 290 300 310 320 330 340 250 260 270 280 290 300 pF1KB4 VSKCLAEYSSPECCKPDLKKLVWIVSRRTAQNLHNSYYSVPELPTIPEGGCFDESESEDS : . : .: : CCDS34 VMQQLRSLQSSSCTDNFVSPAN 350 360 344 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 05:46:00 2016 done: Sat Nov 5 05:46:00 2016 Total Scan time: 2.770 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]