FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB4280, 271 aa 1>>>pF1KB4280 271 - 271 aa - 271 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.1045+/-0.000712; mu= 15.7051+/- 0.043 mean_var=61.2097+/-12.297, 0's: 0 Z-trim(109.0): 7 B-trim: 0 in 0/49 Lambda= 0.163932 statistics sampled from 10580 (10586) to 10580 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.699), E-opt: 0.2 (0.325), width: 16 Scan time: 2.550 The best scores are: opt bits E(32554) CCDS13770.1 COMT gene_id:1312|Hs108|chr22 ( 271) 1830 440.9 4.4e-124 CCDS46663.1 COMT gene_id:1312|Hs108|chr22 ( 221) 1485 359.3 1.3e-99 CCDS44668.1 LRTOMT gene_id:220074|Hs108|chr11 ( 291) 569 142.7 2.8e-34 >>CCDS13770.1 COMT gene_id:1312|Hs108|chr22 (271 aa) initn: 1830 init1: 1830 opt: 1830 Z-score: 2341.2 bits: 440.9 E(32554): 4.4e-124 Smith-Waterman score: 1830; 99.6% identity (100.0% similar) in 271 aa overlap (1-271:1-271) 10 20 30 40 50 60 pF1KB4 MPEAPPLLLAAVLLGLVLLVVLLLLLRHWGWGLCLIGWNEFILQPIHNLLMGDTKEQRIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 MPEAPPLLLAAVLLGLVLLVVLLLLLRHWGWGLCLIGWNEFILQPIHNLLMGDTKEQRIL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 NHVLQHAEPGNAQSVLEAIDTYCEQKEWAMNVGDKKGKIVDAVIQEHQPSVLLELGAYCG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 NHVLQHAEPGNAQSVLEAIDTYCEQKEWAMNVGDKKGKIVDAVIQEHQPSVLLELGAYCG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 YSAVRMARLLSPGARLITIEINPDCAAITQRMVDFAGMKDKVTLVVGASQDIIPQLKKKY :::::::::::::::::::::::::::::::::::::.:::::::::::::::::::::: CCDS13 YSAVRMARLLSPGARLITIEINPDCAAITQRMVDFAGVKDKVTLVVGASQDIIPQLKKKY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 DVDTLDMVFLDHWKDRYLPDTLLLEECGLLRKGTVLLADNVICPGAPDFLAHVRGSSCFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 DVDTLDMVFLDHWKDRYLPDTLLLEECGLLRKGTVLLADNVICPGAPDFLAHVRGSSCFE 190 200 210 220 230 240 250 260 270 pF1KB4 CTHYQSFLEYREVVDGLEKAIYKGPGSEAGP ::::::::::::::::::::::::::::::: CCDS13 CTHYQSFLEYREVVDGLEKAIYKGPGSEAGP 250 260 270 >>CCDS46663.1 COMT gene_id:1312|Hs108|chr22 (221 aa) initn: 1485 init1: 1485 opt: 1485 Z-score: 1901.6 bits: 359.3 E(32554): 1.3e-99 Smith-Waterman score: 1485; 99.5% identity (100.0% similar) in 221 aa overlap (51-271:1-221) 30 40 50 60 70 80 pF1KB4 VLLLLLRHWGWGLCLIGWNEFILQPIHNLLMGDTKEQRILNHVLQHAEPGNAQSVLEAID :::::::::::::::::::::::::::::: CCDS46 MGDTKEQRILNHVLQHAEPGNAQSVLEAID 10 20 30 90 100 110 120 130 140 pF1KB4 TYCEQKEWAMNVGDKKGKIVDAVIQEHQPSVLLELGAYCGYSAVRMARLLSPGARLITIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 TYCEQKEWAMNVGDKKGKIVDAVIQEHQPSVLLELGAYCGYSAVRMARLLSPGARLITIE 40 50 60 70 80 90 150 160 170 180 190 200 pF1KB4 INPDCAAITQRMVDFAGMKDKVTLVVGASQDIIPQLKKKYDVDTLDMVFLDHWKDRYLPD :::::::::::::::::.:::::::::::::::::::::::::::::::::::::::::: CCDS46 INPDCAAITQRMVDFAGVKDKVTLVVGASQDIIPQLKKKYDVDTLDMVFLDHWKDRYLPD 100 110 120 130 140 150 210 220 230 240 250 260 pF1KB4 TLLLEECGLLRKGTVLLADNVICPGAPDFLAHVRGSSCFECTHYQSFLEYREVVDGLEKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 TLLLEECGLLRKGTVLLADNVICPGAPDFLAHVRGSSCFECTHYQSFLEYREVVDGLEKA 160 170 180 190 200 210 270 pF1KB4 IYKGPGSEAGP ::::::::::: CCDS46 IYKGPGSEAGP 220 >>CCDS44668.1 LRTOMT gene_id:220074|Hs108|chr11 (291 aa) initn: 531 init1: 277 opt: 569 Z-score: 729.0 bits: 142.7 E(32554): 2.8e-34 Smith-Waterman score: 569; 36.3% identity (67.6% similar) in 259 aa overlap (10-266:37-291) 10 20 30 pF1KB4 MPEAPPLLLAAVLLGLVLLVVLLLLLRHWGWGLCLIGWN : .: : :.:.::. ::. : CCDS44 KRKGIAGPGLPDLSCALVLQPRAQVGTMSPAIALAFLPLVVTLLVRYRHYFRLLV----R 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB4 EFILQPIHNLLMGDTKEQRILNHVLQHAEPGNAQSVLEAIDTYCEQKEWAMNVGDKKGKI .:. ... : : :.: ...:: :: ::. .: ..: . . :. ..: ::.: CCDS44 TVLLRSLRDCLSGLRIEERAFSYVLTHALPGDPGHILTTLDHWSSRCEYLSHMGPVKGQI 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB4 VDAVIQEHQPSVLLELGAYCGYSAVRMARLLSPGARLITIEINPDCAAITQRMVDFAGMK . ...:. :. .::::.:::::.. .:: : ::.::.:.: .: ::...... .::. CCDS44 LMRLVEEKAPACVLELGTYCGYSTLLIARALPPGGRLLTVERDPRTAAVAEKLIRLAGFD 130 140 150 160 170 180 160 170 180 190 200 210 pF1KB4 DK-VTLVVGASQDIIPQLKKKYDVDTLDMVFLDHWKDRYLPDTLLLEECGLLRKGTVLLA .. : :.::.:.:.:: :. .:... :.:.: : :: : ::: .:: :...:: CCDS44 EHMVELIVGSSEDVIPCLRTQYQLSRADLVLLAHRPRCYLRDLQLLEAHALLPAGATVLA 190 200 210 220 230 240 220 230 240 250 260 270 pF1KB4 DNVICPGAPDFLAHVRGSSCFECT-HYQSFLEYREVVDGLEKAIYKGPGSEAGP :.:. :::: :: .... . ..: :. .. .. . ::. . : ::: CCDS44 DHVLFPGAPRFLQYAKSCGRYRCRLHHTGLPDFPAIKDGIAQLTYAGPG 250 260 270 280 290 271 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 02:56:18 2016 done: Fri Nov 4 02:56:18 2016 Total Scan time: 2.550 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]