FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB4286, 235 aa 1>>>pF1KB4286 235 - 235 aa - 235 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.6288+/-0.0009; mu= 13.1024+/- 0.054 mean_var=70.4904+/-14.519, 0's: 0 Z-trim(106.1): 14 B-trim: 3 in 1/47 Lambda= 0.152760 statistics sampled from 8755 (8765) to 8755 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.644), E-opt: 0.2 (0.269), width: 16 Scan time: 2.050 The best scores are: opt bits E(32554) CCDS3223.1 KCNMB2 gene_id:10242|Hs108|chr3 ( 235) 1581 357.2 5.2e-99 CCDS3225.1 KCNMB3 gene_id:27094|Hs108|chr3 ( 277) 636 149.0 2.9e-36 CCDS43172.1 KCNMB3 gene_id:27094|Hs108|chr3 ( 257) 633 148.3 4.4e-36 CCDS43173.1 KCNMB3 gene_id:27094|Hs108|chr3 ( 275) 633 148.4 4.6e-36 CCDS3226.1 KCNMB3 gene_id:27094|Hs108|chr3 ( 279) 633 148.4 4.7e-36 CCDS4373.1 KCNMB1 gene_id:3779|Hs108|chr5 ( 191) 534 126.5 1.2e-29 CCDS8997.1 KCNMB4 gene_id:27345|Hs108|chr12 ( 210) 419 101.1 5.8e-22 CCDS54683.1 KCNMB3 gene_id:27094|Hs108|chr3 ( 173) 381 92.7 1.6e-19 >>CCDS3223.1 KCNMB2 gene_id:10242|Hs108|chr3 (235 aa) initn: 1581 init1: 1581 opt: 1581 Z-score: 1891.1 bits: 357.2 E(32554): 5.2e-99 Smith-Waterman score: 1581; 100.0% identity (100.0% similar) in 235 aa overlap (1-235:1-235) 10 20 30 40 50 60 pF1KB4 MFIWTSGRTSSSYRHDEKRNIYQKIRDHDLLDKRKTVTALKAGEDRAILLGLAMMVCSIM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 MFIWTSGRTSSSYRHDEKRNIYQKIRDHDLLDKRKTVTALKAGEDRAILLGLAMMVCSIM 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 MYFLLGITLLRSYMQSVWTEESQCTLLNASITETFNCSFSCGPDCWKLSQYPCLQVYVNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 MYFLLGITLLRSYMQSVWTEESQCTLLNASITETFNCSFSCGPDCWKLSQYPCLQVYVNL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 TSSGEKLLLYHTEETIKINQKCSYIPKCGKNFEESMSLVNVVMENFRKYQHFSCYSDPEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 TSSGEKLLLYHTEETIKINQKCSYIPKCGKNFEESMSLVNVVMENFRKYQHFSCYSDPEG 130 140 150 160 170 180 190 200 210 220 230 pF1KB4 NQKSVILTKLYSSNVLFHSLFWPTCMMAGGVAIVAMVKLTQYLSLLCERIQRINR ::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 NQKSVILTKLYSSNVLFHSLFWPTCMMAGGVAIVAMVKLTQYLSLLCERIQRINR 190 200 210 220 230 >>CCDS3225.1 KCNMB3 gene_id:27094|Hs108|chr3 (277 aa) initn: 593 init1: 224 opt: 636 Z-score: 764.4 bits: 149.0 E(32554): 2.9e-36 Smith-Waterman score: 636; 41.8% identity (72.0% similar) in 232 aa overlap (7-235:20-247) 10 20 30 40 pF1KB4 MFIWTSGRTSSSYRHDEKRNIYQKIRDHDLLDKRKTVTALKAGEDRA :::. .... :. : : :: .: . . .:::::: CCDS32 MQPFSIPVQITLQGSRRRQGRTAFPASGKKRETDYS---DGDPLDVHKRLPS-SAGEDRA 10 20 30 40 50 50 60 70 80 90 100 pF1KB4 ILLGLAMMVCSIMMYFLLGITLLRSYMQSVWTEESQCTLLNASITETF-NCSFSCGPDCW ..::.::: :..:.:::: :.:. .: :. ::: :: ....: . . .:.:.:: : CCDS32 VMLGFAMMGFSVLMFFLLGTTILKPFMLSIQREESTCTAIHTDIMDDWLDCAFTCGVHCH 60 70 80 90 100 110 110 120 130 140 150 160 pF1KB4 KLSQYPCLQVYVNLTSSGEKLLLYHTEETIKINQKCSYIPKCGKNFEESMSLVNVVMENF ..::::::.:::. :.: ::...::...:: :: : ::: .. .. .. . . : : CCDS32 GQGKYPCLQVFVNLSHPGQKALLHYNEEAVQINPKCFYTPKCHQDRNDLLNSALDIKEFF 120 130 140 150 160 170 170 180 190 200 210 220 pF1KB4 --RKYQHFSCYSDPEGNQKSVILTKLYSSNVLFHSLFWPTCMMAGGVAIVAMVKLTQYLS .. :::. .: .....::: : :.. ..:: ::::. . ::. ::.::.:::.:: CCDS32 DHKNGTPFSCFYSPASQSEDVILIKKYDQMAIFHCLFWPSLTLLGGALIVGMVRLTQHLS 180 190 200 210 220 230 230 pF1KB4 LLCERIQRINR ::::. . . : CCDS32 LLCEKYSTVVRDEVGGKVPYIEQHQFKLCIMRRSKGRAEKS 240 250 260 270 >>CCDS43172.1 KCNMB3 gene_id:27094|Hs108|chr3 (257 aa) initn: 593 init1: 224 opt: 633 Z-score: 761.4 bits: 148.3 E(32554): 4.4e-36 Smith-Waterman score: 633; 43.9% identity (74.1% similar) in 212 aa overlap (27-235:17-227) 10 20 30 40 50 60 pF1KB4 MFIWTSGRTSSSYRHDEKRNIYQKIRDHDLLDKRKTVTALKAGEDRAILLGLAMMVCSIM : : :: .: . . .::::::..::.::: :.. CCDS43 MTAFPASGKKRETDYSDGDPLDVHKRLPS-SAGEDRAVMLGFAMMGFSVL 10 20 30 40 70 80 90 100 110 pF1KB4 MYFLLGITLLRSYMQSVWTEESQCTLLNASITETF-NCSFSCGPDCWKLSQYPCLQVYVN :.:::: :.:. .: :. ::: :: ....: . . .:.:.:: : ..::::::.:: CCDS43 MFFLLGTTILKPFMLSIQREESTCTAIHTDIMDDWLDCAFTCGVHCHGQGKYPCLQVFVN 50 60 70 80 90 100 120 130 140 150 160 170 pF1KB4 LTSSGEKLLLYHTEETIKINQKCSYIPKCGKNFEESMSLVNVVMENF--RKYQHFSCYSD :. :.: ::...::...:: :: : ::: .. .. .. . . : : .. :::. . CCDS43 LSHPGQKALLHYNEEAVQINPKCFYTPKCHQDRNDLLNSALDIKEFFDHKNGTPFSCFYS 110 120 130 140 150 160 180 190 200 210 220 230 pF1KB4 PEGNQKSVILTKLYSSNVLFHSLFWPTCMMAGGVAIVAMVKLTQYLSLLCERIQRINR : .....::: : :.. ..:: ::::. . ::. ::.::.:::.::::::. . . : CCDS43 PASQSEDVILIKKYDQMAIFHCLFWPSLTLLGGALIVGMVRLTQHLSLLCEKYSTVVRDE 170 180 190 200 210 220 CCDS43 VGGKVPYIEQHQFKLCIMRRSKGRAEKS 230 240 250 >>CCDS43173.1 KCNMB3 gene_id:27094|Hs108|chr3 (275 aa) initn: 593 init1: 224 opt: 633 Z-score: 760.9 bits: 148.4 E(32554): 4.6e-36 Smith-Waterman score: 633; 43.9% identity (74.1% similar) in 212 aa overlap (27-235:35-245) 10 20 30 40 50 pF1KB4 MFIWTSGRTSSSYRHDEKRNIYQKIRDHDLLDKRKTVTALKAGEDRAILLGLAMMV : : :: .: . . .::::::..::.::: CCDS43 LYELTAVSPSPFPQRTAFPASGKKRETDYSDGDPLDVHKRLPS-SAGEDRAVMLGFAMMG 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB4 CSIMMYFLLGITLLRSYMQSVWTEESQCTLLNASITETF-NCSFSCGPDCWKLSQYPCLQ :..:.:::: :.:. .: :. ::: :: ....: . . .:.:.:: : ..::::: CCDS43 FSVLMFFLLGTTILKPFMLSIQREESTCTAIHTDIMDDWLDCAFTCGVHCHGQGKYPCLQ 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB4 VYVNLTSSGEKLLLYHTEETIKINQKCSYIPKCGKNFEESMSLVNVVMENF--RKYQHFS :.:::. :.: ::...::...:: :: : ::: .. .. .. . . : : .. :: CCDS43 VFVNLSHPGQKALLHYNEEAVQINPKCFYTPKCHQDRNDLLNSALDIKEFFDHKNGTPFS 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB4 CYSDPEGNQKSVILTKLYSSNVLFHSLFWPTCMMAGGVAIVAMVKLTQYLSLLCERIQRI :. .: .....::: : :.. ..:: ::::. . ::. ::.::.:::.::::::. . . CCDS43 CFYSPASQSEDVILIKKYDQMAIFHCLFWPSLTLLGGALIVGMVRLTQHLSLLCEKYSTV 190 200 210 220 230 240 pF1KB4 NR : CCDS43 VRDEVGGKVPYIEQHQFKLCIMRRSKGRAEKS 250 260 270 >>CCDS3226.1 KCNMB3 gene_id:27094|Hs108|chr3 (279 aa) initn: 593 init1: 224 opt: 633 Z-score: 760.8 bits: 148.4 E(32554): 4.7e-36 Smith-Waterman score: 633; 43.9% identity (74.1% similar) in 212 aa overlap (27-235:39-249) 10 20 30 40 50 pF1KB4 MFIWTSGRTSSSYRHDEKRNIYQKIRDHDLLDKRKTVTALKAGEDRAILLGLAMMV : : :: .: . . .::::::..::.::: CCDS32 LGFHFVAFILLTRHRTAFPASGKKRETDYSDGDPLDVHKRLPS-SAGEDRAVMLGFAMMG 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB4 CSIMMYFLLGITLLRSYMQSVWTEESQCTLLNASITETF-NCSFSCGPDCWKLSQYPCLQ :..:.:::: :.:. .: :. ::: :: ....: . . .:.:.:: : ..::::: CCDS32 FSVLMFFLLGTTILKPFMLSIQREESTCTAIHTDIMDDWLDCAFTCGVHCHGQGKYPCLQ 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB4 VYVNLTSSGEKLLLYHTEETIKINQKCSYIPKCGKNFEESMSLVNVVMENF--RKYQHFS :.:::. :.: ::...::...:: :: : ::: .. .. .. . . : : .. :: CCDS32 VFVNLSHPGQKALLHYNEEAVQINPKCFYTPKCHQDRNDLLNSALDIKEFFDHKNGTPFS 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB4 CYSDPEGNQKSVILTKLYSSNVLFHSLFWPTCMMAGGVAIVAMVKLTQYLSLLCERIQRI :. .: .....::: : :.. ..:: ::::. . ::. ::.::.:::.::::::. . . CCDS32 CFYSPASQSEDVILIKKYDQMAIFHCLFWPSLTLLGGALIVGMVRLTQHLSLLCEKYSTV 190 200 210 220 230 240 pF1KB4 NR : CCDS32 VRDEVGGKVPYIEQHQFKLCIMRRSKGRAEKS 250 260 270 >>CCDS4373.1 KCNMB1 gene_id:3779|Hs108|chr5 (191 aa) initn: 532 init1: 339 opt: 534 Z-score: 645.4 bits: 126.5 E(32554): 1.2e-29 Smith-Waterman score: 534; 43.5% identity (73.1% similar) in 193 aa overlap (34-226:3-187) 10 20 30 40 50 60 pF1KB4 WTSGRTSSSYRHDEKRNIYQKIRDHDLLDKRKTVTALKAGEDRAILLGLAMMVCSIMMYF .: : : : :: ::. ::..:.::... :. CCDS43 MVKKLVMAQKRGETRALCLGVTMVVCAVITYY 10 20 30 70 80 90 100 110 120 pF1KB4 LLGITLLRSYMQSVWTEESQCTLLNASITETFNCSFSCGPDCWKLSQYPCLQVYVNLTSS .: :.: :..::::.::.: :....: . . . : :. ::::: .::.... CCDS43 ILVTTVLPLYQKSVWTQESKCHLIETNIRDQEELK---GK---KVPQYPCL--WVNVSAA 40 50 60 70 80 130 140 150 160 170 180 pF1KB4 GEKLLLYHTEETIKINQKCSYIPKCGKNFEESMSLVNVVMENFRKYQHFSCYSDPEGNQK :. .:::::.: ::.::::: :.. . . :. : .:.. : : :.: :.::. CCDS43 GRWAVLYHTEDTRDQNQQCSYIPGSVDNYQTARADVEKVRAKFQEQQVFYCFSAPRGNET 90 100 110 120 130 140 190 200 210 220 230 pF1KB4 SVILTKLYSSNVLFHSLFWPTCMMAGGVAIVAMVKLTQYLSLLCERIQRINR ::.. .::. ..:. :::::: ...::. :.:::: .::::.: CCDS43 SVLFQRLYGPQALLFSLFWPTFLLTGGLLIIAMVKSNQYLSILAAQK 150 160 170 180 190 >>CCDS8997.1 KCNMB4 gene_id:27345|Hs108|chr12 (210 aa) initn: 332 init1: 243 opt: 419 Z-score: 507.8 bits: 101.1 E(32554): 5.8e-22 Smith-Waterman score: 419; 32.4% identity (65.2% similar) in 210 aa overlap (31-232:1-206) 10 20 30 40 50 60 pF1KB4 MFIWTSGRTSSSYRHDEKRNIYQKIRDHDLLDKRKTVTALKAGEDRAILLGLAMMVCSIM . : ... .::..: ::: ... ... CCDS89 MAKLRVAYEYTEAEDKSIRLGLFLIISGVV 10 20 30 70 80 90 100 110 pF1KB4 MYFLLGITLLRSYMQSVWTEESQCTLLNAS-ITETFNCSFSCGPDCWKLSQYPCLQVYVN :..:. : .:.. . :..::.:... : :.:.:.:.:: :: :::::.::::: CCDS89 SLFIFGFCWLSPALQDLQATEANCTVLSVQQIGEVFECTFTCGADCRGTSQYPCVQVYVN 40 50 60 70 80 90 120 130 140 150 160 170 pF1KB4 LTSSGEKLLLYHTEETIKINQKCSYIPKCGKNFEESMSLVNVVMENFRKY-------QHF . :. . ::. :. . : :::::: : . :... .. :: :...: : : CCDS89 NSESNSRALLHSDEHQLLTNPKCSYIPPCKR---ENQKNLESVM-NWQQYWKDEIGSQPF 100 110 120 130 140 180 190 200 210 220 230 pF1KB4 SCYSDPEGNQKSVILTKLYSSNVLFHSLFWPTCMMAGGVAIVAMVKLTQYLSLLCERIQR .:: . . .:.: . .. ::.: ..:: .. :: ::... .. :.. : ... CCDS89 TCYFNQHQRPDDVLLHRTHDEIVLLHCFLWPLVTFVVGVLIVVLTICAKSLAVKAEAMKK 150 160 170 180 190 200 pF1KB4 INR CCDS89 RKFS 210 >>CCDS54683.1 KCNMB3 gene_id:27094|Hs108|chr3 (173 aa) initn: 335 init1: 192 opt: 381 Z-score: 463.9 bits: 92.7 E(32554): 1.6e-19 Smith-Waterman score: 381; 39.2% identity (71.2% similar) in 153 aa overlap (7-158:20-167) 10 20 30 40 pF1KB4 MFIWTSGRTSSSYRHDEKRNIYQKIRDHDLLDKRKTVTALKAGEDRA :::. .... :. : : :: .: . . .:::::: CCDS54 MQPFSIPVQITLQGSRRRQGRTAFPASGKKRETDYS---DGDPLDVHKRLPS-SAGEDRA 10 20 30 40 50 50 60 70 80 90 100 pF1KB4 ILLGLAMMVCSIMMYFLLGITLLRSYMQSVWTEESQCTLLNASITETF-NCSFSCGPDCW ..::.::: :..:.:::: :.:. .: :. ::: :: ....: . . .:.:.:: : CCDS54 VMLGFAMMGFSVLMFFLLGTTILKPFMLSIQREESTCTAIHTDIMDDWLDCAFTCGVHCH 60 70 80 90 100 110 110 120 130 140 150 160 pF1KB4 KLSQYPCLQVYVNLTSSGEKLLLYHTEETIKINQKCSYIPKCGKNFEESMSLVNVVMENF ..::::::.:::. :.: ::...::...:: : . . : . ...... CCDS54 GQGKYPCLQVFVNLSHPGQKALLHYNEEAVQINPKRD-VTDCRVKEKQTLTVSDEHKQ 120 130 140 150 160 170 170 180 190 200 210 220 pF1KB4 RKYQHFSCYSDPEGNQKSVILTKLYSSNVLFHSLFWPTCMMAGGVAIVAMVKLTQYLSLL 235 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 05:46:35 2016 done: Sat Nov 5 05:46:35 2016 Total Scan time: 2.050 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]