FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB4303, 635 aa 1>>>pF1KB4303 635 - 635 aa - 635 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 9.1920+/-0.000463; mu= 3.4180+/- 0.028 mean_var=528.9077+/-116.277, 0's: 0 Z-trim(121.4): 1403 B-trim: 0 in 0/56 Lambda= 0.055768 statistics sampled from 36019 (37903) to 36019 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.765), E-opt: 0.2 (0.444), width: 16 Scan time: 12.830 The best scores are: opt bits E(85289) NP_001075031 (OMIM: 160900,605377) myotonin-protei ( 625) 3951 333.4 1.4e-90 NP_001075032 (OMIM: 160900,605377) myotonin-protei ( 639) 3754 317.6 8.5e-86 NP_001275694 (OMIM: 160900,605377) myotonin-protei ( 541) 3707 313.7 1.1e-84 NP_001075029 (OMIM: 160900,605377) myotonin-protei ( 624) 3308 281.7 5.3e-75 NP_001275693 (OMIM: 160900,605377) myotonin-protei ( 655) 3291 280.4 1.4e-74 NP_004400 (OMIM: 160900,605377) myotonin-protein k ( 629) 3288 280.1 1.6e-74 NP_001275695 (OMIM: 160900,605377) myotonin-protei ( 530) 3189 272.0 3.7e-72 XP_016858071 (OMIM: 603412) PREDICTED: serine/thre (1589) 1580 143.3 6.1e-33 NP_055641 (OMIM: 603412) serine/threonine-protein (1638) 1580 143.4 6.2e-33 NP_003598 (OMIM: 603412) serine/threonine-protein (1719) 1580 143.4 6.3e-33 XP_005273381 (OMIM: 603412) PREDICTED: serine/thre (1732) 1580 143.4 6.4e-33 XP_005273379 (OMIM: 603412) PREDICTED: serine/thre (1754) 1580 143.4 6.4e-33 XP_011542611 (OMIM: 603412) PREDICTED: serine/thre (1764) 1580 143.4 6.4e-33 XP_016858067 (OMIM: 603412) PREDICTED: serine/thre (1767) 1580 143.4 6.4e-33 XP_005273378 (OMIM: 603412) PREDICTED: serine/thre (1781) 1580 143.4 6.5e-33 XP_011542610 (OMIM: 603412) PREDICTED: serine/thre (1783) 1580 143.4 6.5e-33 XP_005273377 (OMIM: 603412) PREDICTED: serine/thre (1794) 1580 143.4 6.5e-33 XP_006711898 (OMIM: 603412) PREDICTED: serine/thre (1797) 1580 143.4 6.5e-33 XP_011542609 (OMIM: 603412) PREDICTED: serine/thre (1810) 1580 143.4 6.5e-33 XP_006711897 (OMIM: 603412) PREDICTED: serine/thre (1816) 1580 143.4 6.5e-33 XP_005273375 (OMIM: 603412) PREDICTED: serine/thre (1829) 1580 143.4 6.5e-33 XP_005273374 (OMIM: 603412) PREDICTED: serine/thre (1832) 1580 143.4 6.6e-33 XP_011542608 (OMIM: 603412) PREDICTED: serine/thre (1845) 1580 143.4 6.6e-33 XP_016873487 (OMIM: 613991) PREDICTED: serine/thre (1081) 1552 140.8 2.4e-32 XP_011543463 (OMIM: 613991) PREDICTED: serine/thre (1135) 1552 140.9 2.4e-32 XP_016873486 (OMIM: 613991) PREDICTED: serine/thre (1139) 1552 140.9 2.4e-32 XP_011543461 (OMIM: 613991) PREDICTED: serine/thre (1481) 1552 141.0 2.8e-32 XP_011543460 (OMIM: 613991) PREDICTED: serine/thre (1495) 1552 141.0 2.8e-32 XP_011543459 (OMIM: 613991) PREDICTED: serine/thre (1530) 1552 141.1 2.8e-32 NP_059995 (OMIM: 613991) serine/threonine-protein (1551) 1552 141.1 2.9e-32 XP_011543458 (OMIM: 613991) PREDICTED: serine/thre (1562) 1552 141.1 2.9e-32 XP_016873485 (OMIM: 613991) PREDICTED: serine/thre (1568) 1552 141.1 2.9e-32 XP_011543457 (OMIM: 613991) PREDICTED: serine/thre (1569) 1552 141.1 2.9e-32 XP_011535689 (OMIM: 614062) PREDICTED: serine/thre (1460) 1540 140.1 5.4e-32 XP_005268287 (OMIM: 614062) PREDICTED: serine/thre (1490) 1540 140.1 5.5e-32 XP_005268286 (OMIM: 614062) PREDICTED: serine/thre (1685) 1540 140.2 5.8e-32 XP_005268285 (OMIM: 614062) PREDICTED: serine/thre (1702) 1540 140.2 5.9e-32 NP_006026 (OMIM: 614062) serine/threonine-protein (1711) 1540 140.2 5.9e-32 XP_005268284 (OMIM: 614062) PREDICTED: serine/thre (1728) 1540 140.2 5.9e-32 XP_016858070 (OMIM: 603412) PREDICTED: serine/thre (1712) 1391 128.2 2.4e-28 XP_016858069 (OMIM: 603412) PREDICTED: serine/thre (1741) 1391 128.2 2.4e-28 XP_016858068 (OMIM: 603412) PREDICTED: serine/thre (1741) 1391 128.2 2.4e-28 XP_011543462 (OMIM: 613991) PREDICTED: serine/thre (1471) 1340 124.0 3.8e-27 NP_005397 (OMIM: 601702) rho-associated protein ki (1354) 1206 113.1 6.4e-24 NP_004841 (OMIM: 604002) rho-associated protein ki (1388) 1191 111.9 1.5e-23 XP_016860867 (OMIM: 604002) PREDICTED: rho-associa (1404) 1191 112.0 1.5e-23 XP_005246247 (OMIM: 604002) PREDICTED: rho-associa (1417) 1191 112.0 1.5e-23 NP_001308572 (OMIM: 604002) rho-associated protein (1302) 1172 110.4 4.2e-23 XP_016860868 (OMIM: 604002) PREDICTED: rho-associa (1331) 1172 110.4 4.2e-23 XP_011508719 (OMIM: 604002) PREDICTED: rho-associa (1331) 1172 110.4 4.2e-23 >>NP_001075031 (OMIM: 160900,605377) myotonin-protein ki (625 aa) initn: 3947 init1: 3947 opt: 3951 Z-score: 1747.1 bits: 333.4 E(85289): 1.4e-90 Smith-Waterman score: 3951; 97.5% identity (98.3% similar) in 591 aa overlap (45-635:36-625) 20 30 40 50 60 70 pF1KB4 MWGSPWEADSPRVKLRGREKGRQTEGGAFPLVSSALSGDPRFFSPTTPPAEPIVVRLKEV : .: :. : .. . ::::::::::: NP_001 RLRRLQQLVLDPGFLGLEPLLDLLLGVHQELGASELAQD-KYVADFLQWAEPIVVRLKEV 10 20 30 40 50 60 80 90 100 110 120 130 pF1KB4 RLQRDDFEILKVIGRGAFSEVAVVKMKQTGQVYAMKIMNKWDMLKRGEVSCFREERDVLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RLQRDDFEILKVIGRGAFSEVAVVKMKQTGQVYAMKIMNKWDMLKRGEVSCFREERDVLV 70 80 90 100 110 120 140 150 160 170 180 190 pF1KB4 NGDRRWITQLHFAFQDENYLYLVMEYYVGGDLLTLLSKFGERIPAEMARFYLAEIVMAID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NGDRRWITQLHFAFQDENYLYLVMEYYVGGDLLTLLSKFGERIPAEMARFYLAEIVMAID 130 140 150 160 170 180 200 210 220 230 240 250 pF1KB4 SVHRLGYVHRDIKPDNILLDRCGHIRLADFGSCLKLRADGTVRSLVAVGTPDYLSPEILQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SVHRLGYVHRDIKPDNILLDRCGHIRLADFGSCLKLRADGTVRSLVAVGTPDYLSPEILQ 190 200 210 220 230 240 260 270 280 290 300 310 pF1KB4 AVGGGPGTGSYGPECDWWALGVFAYEMFYGQTPFYADSTAETYGKIVHYKEHLSLPLVDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AVGGGPGTGSYGPECDWWALGVFAYEMFYGQTPFYADSTAETYGKIVHYKEHLSLPLVDE 250 260 270 280 290 300 320 330 340 350 360 370 pF1KB4 GVPEEARDFIQRLLCPPETRLGRGGAGDFRTHPFFFGLDWDGLRDSVPPFTPDFEGATDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GVPEEARDFIQRLLCPPETRLGRGGAGDFRTHPFFFGLDWDGLRDSVPPFTPDFEGATDT 310 320 330 340 350 360 380 390 400 410 420 430 pF1KB4 CNFDLVEDGLTAMETLSDIREGAPLGVHLPFVGYSYSCMALRDSEVPGPTPMELEAEQLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CNFDLVEDGLTAMETLSDIREGAPLGVHLPFVGYSYSCMALRDSEVPGPTPMELEAEQLL 370 380 390 400 410 420 440 450 460 470 480 490 pF1KB4 EPHVQAPSLEPSVSPQDETAEVAVPAAVPAAEAEAEVTLRELQEALEEEVLTRQSLSREM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EPHVQAPSLEPSVSPQDETAEVAVPAAVPAAEAEAEVTLRELQEALEEEVLTRQSLSREM 430 440 450 460 470 480 500 510 520 530 540 550 pF1KB4 EAIRTDNQNFASQLREAEARNRDLEAHVRQLQERMELLQAEGATAVTGVPSPRATDPPSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EAIRTDNQNFASQLREAEARNRDLEAHVRQLQERMELLQAEGATAVTGVPSPRATDPPSH 490 500 510 520 530 540 560 570 580 590 600 610 pF1KB4 MAPRPWLWASARWWGQAPCTAATCCSLPGSLGLAYRRRFPCSCSPLFCLVPPPWAALGWW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAPRPWLWASARWWGQAPCTAATCCSLPGSLGLAYRRRFPCSCSPLFCLVPPPWAALGWW 550 560 570 580 590 600 620 630 pF1KB4 PTPANSPQSGAAQEPPALPEP ::::::::::::::::::::: NP_001 PTPANSPQSGAAQEPPALPEP 610 620 >>NP_001075032 (OMIM: 160900,605377) myotonin-protein ki (639 aa) initn: 3760 init1: 2698 opt: 3754 Z-score: 1661.3 bits: 317.6 E(85289): 8.5e-86 Smith-Waterman score: 3754; 98.4% identity (98.6% similar) in 564 aa overlap (1-559:1-564) 10 20 30 40 50 60 pF1KB4 MGGHFWPPEPYTVFMWGSPWEADSPRVKLRGREKGRQTEGGAFPLVSSALSGDPRFFSPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MGGHFWPPEPYTVFMWGSPWEADSPRVKLRGREKGRQTEGGAFPLVSSALSGDPRFFSPT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 TPPAEPIVVRLKEVRLQRDDFEILKVIGRGAFSEVAVVKMKQTGQVYAMKIMNKWDMLKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TPPAEPIVVRLKEVRLQRDDFEILKVIGRGAFSEVAVVKMKQTGQVYAMKIMNKWDMLKR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 GEVSCFREERDVLVNGDRRWITQLHFAFQDENYLYLVMEYYVGGDLLTLLSKFGERIPAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GEVSCFREERDVLVNGDRRWITQLHFAFQDENYLYLVMEYYVGGDLLTLLSKFGERIPAE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 MARFYLAEIVMAIDSVHRLGYVHRDIKPDNILLDRCGHIRLADFGSCLKLRADGTVRSLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MARFYLAEIVMAIDSVHRLGYVHRDIKPDNILLDRCGHIRLADFGSCLKLRADGTVRSLV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 AVGTPDYLSPEILQAVGGGPGTGSYGPECDWWALGVFAYEMFYGQTPFYADSTAETYGKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AVGTPDYLSPEILQAVGGGPGTGSYGPECDWWALGVFAYEMFYGQTPFYADSTAETYGKI 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 VHYKEHLSLPLVDEGVPEEARDFIQRLLCPPETRLGRGGAGDFRTHPFFFGLDWDGLRDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VHYKEHLSLPLVDEGVPEEARDFIQRLLCPPETRLGRGGAGDFRTHPFFFGLDWDGLRDS 310 320 330 340 350 360 370 380 390 400 410 pF1KB4 VPPFTPDFEGATDTCNFDLVEDGLTAM-----ETLSDIREGAPLGVHLPFVGYSYSCMAL ::::::::::::::::::::::::::: :::::::::::::::::::::::::::: NP_001 VPPFTPDFEGATDTCNFDLVEDGLTAMVSGGGETLSDIREGAPLGVHLPFVGYSYSCMAL 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB4 RDSEVPGPTPMELEAEQLLEPHVQAPSLEPSVSPQDETAEVAVPAAVPAAEAEAEVTLRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RDSEVPGPTPMELEAEQLLEPHVQAPSLEPSVSPQDETAEVAVPAAVPAAEAEAEVTLRE 430 440 450 460 470 480 480 490 500 510 520 530 pF1KB4 LQEALEEEVLTRQSLSREMEAIRTDNQNFASQLREAEARNRDLEAHVRQLQERMELLQAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LQEALEEEVLTRQSLSREMEAIRTDNQNFASQLREAEARNRDLEAHVRQLQERMELLQAE 490 500 510 520 530 540 540 550 560 570 580 590 pF1KB4 GATAVTGVPSPRATDPPSHMAPRPWLWASARWWGQAPCTAATCCSLPGSLGLAYRRRFPC :::::::::::::::::::. : NP_001 GATAVTGVPSPRATDPPSHLDGPPAVAVGQCPLVGPGPMHRRHLLLPARVPRPGLSEALS 550 560 570 580 590 600 >>NP_001275694 (OMIM: 160900,605377) myotonin-protein ki (541 aa) initn: 3713 init1: 2008 opt: 3707 Z-score: 1641.6 bits: 313.7 E(85289): 1.1e-84 Smith-Waterman score: 3707; 99.1% identity (99.1% similar) in 541 aa overlap (100-635:1-541) 70 80 90 100 110 120 pF1KB4 RLKEVRLQRDDFEILKVIGRGAFSEVAVVKMKQTGQVYAMKIMNKWDMLKRGEVSCFREE :::::::::::::::::::::::::::::: NP_001 MKQTGQVYAMKIMNKWDMLKRGEVSCFREE 10 20 30 130 140 150 160 170 180 pF1KB4 RDVLVNGDRRWITQLHFAFQDENYLYLVMEYYVGGDLLTLLSKFGERIPAEMARFYLAEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RDVLVNGDRRWITQLHFAFQDENYLYLVMEYYVGGDLLTLLSKFGERIPAEMARFYLAEI 40 50 60 70 80 90 190 200 210 220 230 240 pF1KB4 VMAIDSVHRLGYVHRDIKPDNILLDRCGHIRLADFGSCLKLRADGTVRSLVAVGTPDYLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VMAIDSVHRLGYVHRDIKPDNILLDRCGHIRLADFGSCLKLRADGTVRSLVAVGTPDYLS 100 110 120 130 140 150 250 260 270 280 290 300 pF1KB4 PEILQAVGGGPGTGSYGPECDWWALGVFAYEMFYGQTPFYADSTAETYGKIVHYKEHLSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PEILQAVGGGPGTGSYGPECDWWALGVFAYEMFYGQTPFYADSTAETYGKIVHYKEHLSL 160 170 180 190 200 210 310 320 330 340 350 360 pF1KB4 PLVDEGVPEEARDFIQRLLCPPETRLGRGGAGDFRTHPFFFGLDWDGLRDSVPPFTPDFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PLVDEGVPEEARDFIQRLLCPPETRLGRGGAGDFRTHPFFFGLDWDGLRDSVPPFTPDFE 220 230 240 250 260 270 370 380 390 400 410 420 pF1KB4 GATDTCNFDLVEDGLTAM-----ETLSDIREGAPLGVHLPFVGYSYSCMALRDSEVPGPT :::::::::::::::::: ::::::::::::::::::::::::::::::::::::: NP_001 GATDTCNFDLVEDGLTAMVSGGGETLSDIREGAPLGVHLPFVGYSYSCMALRDSEVPGPT 280 290 300 310 320 330 430 440 450 460 470 480 pF1KB4 PMELEAEQLLEPHVQAPSLEPSVSPQDETAEVAVPAAVPAAEAEAEVTLRELQEALEEEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PMELEAEQLLEPHVQAPSLEPSVSPQDETAEVAVPAAVPAAEAEAEVTLRELQEALEEEV 340 350 360 370 380 390 490 500 510 520 530 540 pF1KB4 LTRQSLSREMEAIRTDNQNFASQLREAEARNRDLEAHVRQLQERMELLQAEGATAVTGVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LTRQSLSREMEAIRTDNQNFASQLREAEARNRDLEAHVRQLQERMELLQAEGATAVTGVP 400 410 420 430 440 450 550 560 570 580 590 600 pF1KB4 SPRATDPPSHMAPRPWLWASARWWGQAPCTAATCCSLPGSLGLAYRRRFPCSCSPLFCLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SPRATDPPSHMAPRPWLWASARWWGQAPCTAATCCSLPGSLGLAYRRRFPCSCSPLFCLV 460 470 480 490 500 510 610 620 630 pF1KB4 PPPWAALGWWPTPANSPQSGAAQEPPALPEP ::::::::::::::::::::::::::::::: NP_001 PPPWAALGWWPTPANSPQSGAAQEPPALPEP 520 530 540 >>NP_001075029 (OMIM: 160900,605377) myotonin-protein ki (624 aa) initn: 3304 init1: 3304 opt: 3308 Z-score: 1467.5 bits: 281.7 E(85289): 5.3e-75 Smith-Waterman score: 3308; 96.3% identity (97.5% similar) in 515 aa overlap (45-559:36-549) 20 30 40 50 60 70 pF1KB4 MWGSPWEADSPRVKLRGREKGRQTEGGAFPLVSSALSGDPRFFSPTTPPAEPIVVRLKEV : .: :. : .. . ::::::::::: NP_001 RLRRLQQLVLDPGFLGLEPLLDLLLGVHQELGASELAQD-KYVADFLQWAEPIVVRLKEV 10 20 30 40 50 60 80 90 100 110 120 130 pF1KB4 RLQRDDFEILKVIGRGAFSEVAVVKMKQTGQVYAMKIMNKWDMLKRGEVSCFREERDVLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RLQRDDFEILKVIGRGAFSEVAVVKMKQTGQVYAMKIMNKWDMLKRGEVSCFREERDVLV 70 80 90 100 110 120 140 150 160 170 180 190 pF1KB4 NGDRRWITQLHFAFQDENYLYLVMEYYVGGDLLTLLSKFGERIPAEMARFYLAEIVMAID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NGDRRWITQLHFAFQDENYLYLVMEYYVGGDLLTLLSKFGERIPAEMARFYLAEIVMAID 130 140 150 160 170 180 200 210 220 230 240 250 pF1KB4 SVHRLGYVHRDIKPDNILLDRCGHIRLADFGSCLKLRADGTVRSLVAVGTPDYLSPEILQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SVHRLGYVHRDIKPDNILLDRCGHIRLADFGSCLKLRADGTVRSLVAVGTPDYLSPEILQ 190 200 210 220 230 240 260 270 280 290 300 310 pF1KB4 AVGGGPGTGSYGPECDWWALGVFAYEMFYGQTPFYADSTAETYGKIVHYKEHLSLPLVDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AVGGGPGTGSYGPECDWWALGVFAYEMFYGQTPFYADSTAETYGKIVHYKEHLSLPLVDE 250 260 270 280 290 300 320 330 340 350 360 370 pF1KB4 GVPEEARDFIQRLLCPPETRLGRGGAGDFRTHPFFFGLDWDGLRDSVPPFTPDFEGATDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GVPEEARDFIQRLLCPPETRLGRGGAGDFRTHPFFFGLDWDGLRDSVPPFTPDFEGATDT 310 320 330 340 350 360 380 390 400 410 420 430 pF1KB4 CNFDLVEDGLTAMETLSDIREGAPLGVHLPFVGYSYSCMALRDSEVPGPTPMELEAEQLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CNFDLVEDGLTAMETLSDIREGAPLGVHLPFVGYSYSCMALRDSEVPGPTPMELEAEQLL 370 380 390 400 410 420 440 450 460 470 480 490 pF1KB4 EPHVQAPSLEPSVSPQDETAEVAVPAAVPAAEAEAEVTLRELQEALEEEVLTRQSLSREM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EPHVQAPSLEPSVSPQDETAEVAVPAAVPAAEAEAEVTLRELQEALEEEVLTRQSLSREM 430 440 450 460 470 480 500 510 520 530 540 550 pF1KB4 EAIRTDNQNFASQLREAEARNRDLEAHVRQLQERMELLQAEGATAVTGVPSPRATDPPSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EAIRTDNQNFASQLREAEARNRDLEAHVRQLQERMELLQAEGATAVTGVPSPRATDPPSH 490 500 510 520 530 540 560 570 580 590 600 610 pF1KB4 MAPRPWLWASARWWGQAPCTAATCCSLPGSLGLAYRRRFPCSCSPLFCLVPPPWAALGWW . : NP_001 LDGPPAVAVGQCPLVGPGPMHRRHLLLPARVPRPGLSEALSLLLFAVVLSRAAALGCIGL 550 560 570 580 590 600 >>NP_001275693 (OMIM: 160900,605377) myotonin-protein ki (655 aa) initn: 3290 init1: 2228 opt: 3291 Z-score: 1459.9 bits: 280.4 E(85289): 1.4e-74 Smith-Waterman score: 3291; 93.3% identity (95.0% similar) in 535 aa overlap (31-559:50-580) 10 20 30 40 50 60 pF1KB4 MGGHFWPPEPYTVFMWGSPWEADSPRVKLRGREKGRQTEGGAFPLVSSALSGDPRFFSPT :. .:: : : ... .: :. NP_001 GVGPGLPGAGAPARPSPGRPPGAGRLRTGPGQVRGRLLAVGPKSRVFQSVVQEP----PA 20 30 40 50 60 70 70 80 90 100 110 pF1KB4 TPP-AEPIVVRLKEVRLQRDDFEILKVIGRGAFSEVAVVKMKQTGQVYAMKIMNKWDMLK . :::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SESRAEPIVVRLKEVRLQRDDFEILKVIGRGAFSEVAVVKMKQTGQVYAMKIMNKWDMLK 80 90 100 110 120 130 120 130 140 150 160 170 pF1KB4 RGEVSCFREERDVLVNGDRRWITQLHFAFQDENYLYLVMEYYVGGDLLTLLSKFGERIPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RGEVSCFREERDVLVNGDRRWITQLHFAFQDENYLYLVMEYYVGGDLLTLLSKFGERIPA 140 150 160 170 180 190 180 190 200 210 220 230 pF1KB4 EMARFYLAEIVMAIDSVHRLGYVHRDIKPDNILLDRCGHIRLADFGSCLKLRADGTVRSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EMARFYLAEIVMAIDSVHRLGYVHRDIKPDNILLDRCGHIRLADFGSCLKLRADGTVRSL 200 210 220 230 240 250 240 250 260 270 280 290 pF1KB4 VAVGTPDYLSPEILQAVGGGPGTGSYGPECDWWALGVFAYEMFYGQTPFYADSTAETYGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VAVGTPDYLSPEILQAVGGGPGTGSYGPECDWWALGVFAYEMFYGQTPFYADSTAETYGK 260 270 280 290 300 310 300 310 320 330 340 350 pF1KB4 IVHYKEHLSLPLVDEGVPEEARDFIQRLLCPPETRLGRGGAGDFRTHPFFFGLDWDGLRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IVHYKEHLSLPLVDEGVPEEARDFIQRLLCPPETRLGRGGAGDFRTHPFFFGLDWDGLRD 320 330 340 350 360 370 360 370 380 390 400 410 pF1KB4 SVPPFTPDFEGATDTCNFDLVEDGLTAM-----ETLSDIREGAPLGVHLPFVGYSYSCMA :::::::::::::::::::::::::::: ::::::::::::::::::::::::::: NP_001 SVPPFTPDFEGATDTCNFDLVEDGLTAMVSGGGETLSDIREGAPLGVHLPFVGYSYSCMA 380 390 400 410 420 430 420 430 440 450 460 470 pF1KB4 LRDSEVPGPTPMELEAEQLLEPHVQAPSLEPSVSPQDETAEVAVPAAVPAAEAEAEVTLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LRDSEVPGPTPMELEAEQLLEPHVQAPSLEPSVSPQDETAEVAVPAAVPAAEAEAEVTLR 440 450 460 470 480 490 480 490 500 510 520 530 pF1KB4 ELQEALEEEVLTRQSLSREMEAIRTDNQNFASQLREAEARNRDLEAHVRQLQERMELLQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ELQEALEEEVLTRQSLSREMEAIRTDNQNFASQLREAEARNRDLEAHVRQLQERMELLQA 500 510 520 530 540 550 540 550 560 570 580 590 pF1KB4 EGATAVTGVPSPRATDPPSHMAPRPWLWASARWWGQAPCTAATCCSLPGSLGLAYRRRFP ::::::::::::::::::::. : NP_001 EGATAVTGVPSPRATDPPSHLDGPPAVAVGQCPLVGPGPMHRRHLLLPARVPRPGLSEAL 560 570 580 590 600 610 >>NP_004400 (OMIM: 160900,605377) myotonin-protein kinas (629 aa) initn: 3290 init1: 2228 opt: 3288 Z-score: 1458.8 bits: 280.1 E(85289): 1.6e-74 Smith-Waterman score: 3288; 95.4% identity (96.5% similar) in 520 aa overlap (45-559:36-554) 20 30 40 50 60 70 pF1KB4 MWGSPWEADSPRVKLRGREKGRQTEGGAFPLVSSALSGDPRFFSPTTPPAEPIVVRLKEV : .: :. : .. . ::::::::::: NP_004 RLRRLQQLVLDPGFLGLEPLLDLLLGVHQELGASELAQD-KYVADFLQWAEPIVVRLKEV 10 20 30 40 50 60 80 90 100 110 120 130 pF1KB4 RLQRDDFEILKVIGRGAFSEVAVVKMKQTGQVYAMKIMNKWDMLKRGEVSCFREERDVLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 RLQRDDFEILKVIGRGAFSEVAVVKMKQTGQVYAMKIMNKWDMLKRGEVSCFREERDVLV 70 80 90 100 110 120 140 150 160 170 180 190 pF1KB4 NGDRRWITQLHFAFQDENYLYLVMEYYVGGDLLTLLSKFGERIPAEMARFYLAEIVMAID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 NGDRRWITQLHFAFQDENYLYLVMEYYVGGDLLTLLSKFGERIPAEMARFYLAEIVMAID 130 140 150 160 170 180 200 210 220 230 240 250 pF1KB4 SVHRLGYVHRDIKPDNILLDRCGHIRLADFGSCLKLRADGTVRSLVAVGTPDYLSPEILQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 SVHRLGYVHRDIKPDNILLDRCGHIRLADFGSCLKLRADGTVRSLVAVGTPDYLSPEILQ 190 200 210 220 230 240 260 270 280 290 300 310 pF1KB4 AVGGGPGTGSYGPECDWWALGVFAYEMFYGQTPFYADSTAETYGKIVHYKEHLSLPLVDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 AVGGGPGTGSYGPECDWWALGVFAYEMFYGQTPFYADSTAETYGKIVHYKEHLSLPLVDE 250 260 270 280 290 300 320 330 340 350 360 370 pF1KB4 GVPEEARDFIQRLLCPPETRLGRGGAGDFRTHPFFFGLDWDGLRDSVPPFTPDFEGATDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 GVPEEARDFIQRLLCPPETRLGRGGAGDFRTHPFFFGLDWDGLRDSVPPFTPDFEGATDT 310 320 330 340 350 360 380 390 400 410 420 pF1KB4 CNFDLVEDGLTAM-----ETLSDIREGAPLGVHLPFVGYSYSCMALRDSEVPGPTPMELE ::::::::::::: :::::::::::::::::::::::::::::::::::::::::: NP_004 CNFDLVEDGLTAMVSGGGETLSDIREGAPLGVHLPFVGYSYSCMALRDSEVPGPTPMELE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB4 AEQLLEPHVQAPSLEPSVSPQDETAEVAVPAAVPAAEAEAEVTLRELQEALEEEVLTRQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 AEQLLEPHVQAPSLEPSVSPQDETAEVAVPAAVPAAEAEAEVTLRELQEALEEEVLTRQS 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB4 LSREMEAIRTDNQNFASQLREAEARNRDLEAHVRQLQERMELLQAEGATAVTGVPSPRAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 LSREMEAIRTDNQNFASQLREAEARNRDLEAHVRQLQERMELLQAEGATAVTGVPSPRAT 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB4 DPPSHMAPRPWLWASARWWGQAPCTAATCCSLPGSLGLAYRRRFPCSCSPLFCLVPPPWA :::::. : NP_004 DPPSHLDGPPAVAVGQCPLVGPGPMHRRHLLLPARVPRPGLSEALSLLLFAVVLSRAAAL 550 560 570 580 590 600 >>NP_001275695 (OMIM: 160900,605377) myotonin-protein ki (530 aa) initn: 3185 init1: 3185 opt: 3189 Z-score: 1416.4 bits: 272.0 E(85289): 3.7e-72 Smith-Waterman score: 3189; 97.0% identity (98.0% similar) in 494 aa overlap (45-538:36-528) 20 30 40 50 60 70 pF1KB4 MWGSPWEADSPRVKLRGREKGRQTEGGAFPLVSSALSGDPRFFSPTTPPAEPIVVRLKEV : .: :. : .. . ::::::::::: NP_001 RLRRLQQLVLDPGFLGLEPLLDLLLGVHQELGASELAQD-KYVADFLQWAEPIVVRLKEV 10 20 30 40 50 60 80 90 100 110 120 130 pF1KB4 RLQRDDFEILKVIGRGAFSEVAVVKMKQTGQVYAMKIMNKWDMLKRGEVSCFREERDVLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RLQRDDFEILKVIGRGAFSEVAVVKMKQTGQVYAMKIMNKWDMLKRGEVSCFREERDVLV 70 80 90 100 110 120 140 150 160 170 180 190 pF1KB4 NGDRRWITQLHFAFQDENYLYLVMEYYVGGDLLTLLSKFGERIPAEMARFYLAEIVMAID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NGDRRWITQLHFAFQDENYLYLVMEYYVGGDLLTLLSKFGERIPAEMARFYLAEIVMAID 130 140 150 160 170 180 200 210 220 230 240 250 pF1KB4 SVHRLGYVHRDIKPDNILLDRCGHIRLADFGSCLKLRADGTVRSLVAVGTPDYLSPEILQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SVHRLGYVHRDIKPDNILLDRCGHIRLADFGSCLKLRADGTVRSLVAVGTPDYLSPEILQ 190 200 210 220 230 240 260 270 280 290 300 310 pF1KB4 AVGGGPGTGSYGPECDWWALGVFAYEMFYGQTPFYADSTAETYGKIVHYKEHLSLPLVDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AVGGGPGTGSYGPECDWWALGVFAYEMFYGQTPFYADSTAETYGKIVHYKEHLSLPLVDE 250 260 270 280 290 300 320 330 340 350 360 370 pF1KB4 GVPEEARDFIQRLLCPPETRLGRGGAGDFRTHPFFFGLDWDGLRDSVPPFTPDFEGATDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GVPEEARDFIQRLLCPPETRLGRGGAGDFRTHPFFFGLDWDGLRDSVPPFTPDFEGATDT 310 320 330 340 350 360 380 390 400 410 420 430 pF1KB4 CNFDLVEDGLTAMETLSDIREGAPLGVHLPFVGYSYSCMALRDSEVPGPTPMELEAEQLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CNFDLVEDGLTAMETLSDIREGAPLGVHLPFVGYSYSCMALRDSEVPGPTPMELEAEQLL 370 380 390 400 410 420 440 450 460 470 480 490 pF1KB4 EPHVQAPSLEPSVSPQDETAEVAVPAAVPAAEAEAEVTLRELQEALEEEVLTRQSLSREM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EPHVQAPSLEPSVSPQDETAEVAVPAAVPAAEAEAEVTLRELQEALEEEVLTRQSLSREM 430 440 450 460 470 480 500 510 520 530 540 550 pF1KB4 EAIRTDNQNFASQLREAEARNRDLEAHVRQLQERMELLQAEGATAVTGVPSPRATDPPSH :::::::::::::::::::::::::::::::::::::::::::: NP_001 EAIRTDNQNFASQLREAEARNRDLEAHVRQLQERMELLQAEGATGP 490 500 510 520 530 560 570 580 590 600 610 pF1KB4 MAPRPWLWASARWWGQAPCTAATCCSLPGSLGLAYRRRFPCSCSPLFCLVPPPWAALGWW >>XP_016858071 (OMIM: 603412) PREDICTED: serine/threonin (1589 aa) initn: 1588 init1: 1013 opt: 1580 Z-score: 712.4 bits: 143.3 E(85289): 6.1e-33 Smith-Waterman score: 1611; 52.3% identity (75.5% similar) in 493 aa overlap (64-535:60-543) 40 50 60 70 80 90 pF1KB4 KGRQTEGGAFPLVSSALSGDPRFFSPTTPPAEPIVVRLKEVRLQRDDFEILKVIGRGAFS :.:.. ..:..::.:.:::::::::::::. XP_016 TLLDILICLYDECNNSPLRREKNILEYLEWAKPFTSKVKQMRLHREDFEILKVIGRGAFG 30 40 50 60 70 80 100 110 120 130 140 150 pF1KB4 EVAVVKMKQTGQVYAMKIMNKWDMLKRGEVSCFREERDVLVNGDRRWITQLHFAFQDENY ::::::.:.. .:.::::.:::.::::.:..::::::::::::: .::: ::.::::.: XP_016 EVAVVKLKNADKVFAMKILNKWEMLKRAETACFREERDVLVNGDNKWITTLHYAFQDDNN 90 100 110 120 130 140 160 170 180 190 200 210 pF1KB4 LYLVMEYYVGGDLLTLLSKFGERIPAEMARFYLAEIVMAIDSVHRLGYVHRDIKPDNILL :::::.:::::::::::::: .:.: .::::::::.:.::::::.: ::::::::::::. XP_016 LYLVMDYYVGGDLLTLLSKFEDRLPEDMARFYLAEMVIAIDSVHQLHYVHRDIKPDNILM 150 160 170 180 190 200 220 230 240 250 260 270 pF1KB4 DRCGHIRLADFGSCLKLRADGTVRSLVAVGTPDYLSPEILQAVGGGPGTGSYGPECDWWA : :::::::::::::: ::::.: ::::::::.:::::::. : : ::::::::. XP_016 DMNGHIRLADFGSCLKLMEDGTVQSSVAVGTPDYISPEILQAMEDGKG--RYGPECDWWS 210 220 230 240 250 260 280 290 300 310 320 330 pF1KB4 LGVFAYEMFYGQTPFYADSTAETYGKIVHYKEHLSLPLVDEGVPEEARDFIQRLLCPPET ::: :::.::.:::::.: .::::::...::....: : :.:.:.:.::.: : XP_016 LGVCMYEMLYGETPFYAESLVETYGKIMNHKERFQFPAQVTDVSENAKDLIRRLICSREH 270 280 290 300 310 320 340 350 360 370 380 390 pF1KB4 RLGRGGAGDFRTHPFFFGLDWDGLRDSVPPFTPDFEGATDTCNFDLVEDGLTAMETLSDI :::..: ::. :::: :.:::..:. :. :. . ::: :::. .: : ::. XP_016 RLGQNGIEDFKKHPFFSGIDWDNIRNCEAPYIPEVSSPTDTSNFDVDDDCLKNSETMPPP 330 340 350 360 370 380 400 410 420 430 440 pF1KB4 REGAPLGVHLPFVGYSY--SCMALRDSE----VPGPTPMELEA--EQLLEPHVQAPSLEP . : : ::::::..: ::. : : . ::: ..:.. .. :. .. . . : XP_016 THTAFSGHHLPFVGFTYTSSCV-LSDRSCLRVTAGPTSLDLDVNVQRTLDNNLATEAYER 390 400 410 420 430 440 450 460 470 480 490 pF1KB4 SVSP-QDETAEVAVPAAVPAAEAEAEVTLRELQEALEEEVLTR------QSLSREMEAIR .. ..: :.. :. :.. :: . . :: ..:..:.: .: XP_016 RIKRLEQEKLELSRKLQ------ESTQTVQALQYSTVDGPLTASKDLEIKNLKEEIEKLR 450 460 470 480 490 500 500 510 520 530 540 550 pF1KB4 ---TDNQNFASQLREAEARNRDLEAHVRQLQ---ERMELLQAEGATAVTGVPSPRATDPP :..... .::.::.: ..:. ::.. .... :: : XP_016 KQVTESSHLEQQLEEANAVRQELDDAFRQIKAYEKQIKTLQQEREDLNKELVQASERLKN 510 520 530 540 550 560 560 570 580 590 600 610 pF1KB4 SHMAPRPWLWASARWWGQAPCTAATCCSLPGSLGLAYRRRFPCSCSPLFCLVPPPWAALG XP_016 QSKELKDAHCQRKLAMQEFMEINERLTELHTQKQKLARHVRDKEEEVDLVMQKVESLRQE 570 580 590 600 610 620 >>NP_055641 (OMIM: 603412) serine/threonine-protein kina (1638 aa) initn: 1585 init1: 1013 opt: 1580 Z-score: 712.3 bits: 143.4 E(85289): 6.2e-33 Smith-Waterman score: 1611; 52.3% identity (75.5% similar) in 493 aa overlap (64-535:60-543) 40 50 60 70 80 90 pF1KB4 KGRQTEGGAFPLVSSALSGDPRFFSPTTPPAEPIVVRLKEVRLQRDDFEILKVIGRGAFS :.:.. ..:..::.:.:::::::::::::. NP_055 TLLDILICLYDECNNSPLRREKNILEYLEWAKPFTSKVKQMRLHREDFEILKVIGRGAFG 30 40 50 60 70 80 100 110 120 130 140 150 pF1KB4 EVAVVKMKQTGQVYAMKIMNKWDMLKRGEVSCFREERDVLVNGDRRWITQLHFAFQDENY ::::::.:.. .:.::::.:::.::::.:..::::::::::::: .::: ::.::::.: NP_055 EVAVVKLKNADKVFAMKILNKWEMLKRAETACFREERDVLVNGDNKWITTLHYAFQDDNN 90 100 110 120 130 140 160 170 180 190 200 210 pF1KB4 LYLVMEYYVGGDLLTLLSKFGERIPAEMARFYLAEIVMAIDSVHRLGYVHRDIKPDNILL :::::.:::::::::::::: .:.: .::::::::.:.::::::.: ::::::::::::. NP_055 LYLVMDYYVGGDLLTLLSKFEDRLPEDMARFYLAEMVIAIDSVHQLHYVHRDIKPDNILM 150 160 170 180 190 200 220 230 240 250 260 270 pF1KB4 DRCGHIRLADFGSCLKLRADGTVRSLVAVGTPDYLSPEILQAVGGGPGTGSYGPECDWWA : :::::::::::::: ::::.: ::::::::.:::::::. : : ::::::::. NP_055 DMNGHIRLADFGSCLKLMEDGTVQSSVAVGTPDYISPEILQAMEDGKG--RYGPECDWWS 210 220 230 240 250 260 280 290 300 310 320 330 pF1KB4 LGVFAYEMFYGQTPFYADSTAETYGKIVHYKEHLSLPLVDEGVPEEARDFIQRLLCPPET ::: :::.::.:::::.: .::::::...::....: : :.:.:.:.::.: : NP_055 LGVCMYEMLYGETPFYAESLVETYGKIMNHKERFQFPAQVTDVSENAKDLIRRLICSREH 270 280 290 300 310 320 340 350 360 370 380 390 pF1KB4 RLGRGGAGDFRTHPFFFGLDWDGLRDSVPPFTPDFEGATDTCNFDLVEDGLTAMETLSDI :::..: ::. :::: :.:::..:. :. :. . ::: :::. .: : ::. NP_055 RLGQNGIEDFKKHPFFSGIDWDNIRNCEAPYIPEVSSPTDTSNFDVDDDCLKNSETMPPP 330 340 350 360 370 380 400 410 420 430 440 pF1KB4 REGAPLGVHLPFVGYSY--SCMALRDSE----VPGPTPMELEA--EQLLEPHVQAPSLEP . : : ::::::..: ::. : : . ::: ..:.. .. :. .. . . : NP_055 THTAFSGHHLPFVGFTYTSSCV-LSDRSCLRVTAGPTSLDLDVNVQRTLDNNLATEAYER 390 400 410 420 430 440 450 460 470 480 490 pF1KB4 SVSP-QDETAEVAVPAAVPAAEAEAEVTLRELQEALEEEVLTR------QSLSREMEAIR .. ..: :.. :. :.. :: . . :: ..:..:.: .: NP_055 RIKRLEQEKLELSRKLQ------ESTQTVQALQYSTVDGPLTASKDLEIKNLKEEIEKLR 450 460 470 480 490 500 500 510 520 530 540 550 pF1KB4 ---TDNQNFASQLREAEARNRDLEAHVRQLQ---ERMELLQAEGATAVTGVPSPRATDPP :..... .::.::.: ..:. ::.. .... :: : NP_055 KQVTESSHLEQQLEEANAVRQELDDAFRQIKAYEKQIKTLQQEREDLNKLEVHTEALAAE 510 520 530 540 550 560 560 570 580 590 600 610 pF1KB4 SHMAPRPWLWASARWWGQAPCTAATCCSLPGSLGLAYRRRFPCSCSPLFCLVPPPWAALG NP_055 ASKDRKLREQSEHYSKQLENELEGLKQKQISYSPGVCSIEHQQEITKLKTDLEKKSIFYE 570 580 590 600 610 620 >>NP_003598 (OMIM: 603412) serine/threonine-protein kina (1719 aa) initn: 1585 init1: 1013 opt: 1580 Z-score: 712.1 bits: 143.4 E(85289): 6.3e-33 Smith-Waterman score: 1611; 52.3% identity (75.5% similar) in 493 aa overlap (64-535:60-543) 40 50 60 70 80 90 pF1KB4 KGRQTEGGAFPLVSSALSGDPRFFSPTTPPAEPIVVRLKEVRLQRDDFEILKVIGRGAFS :.:.. ..:..::.:.:::::::::::::. NP_003 TLLDILICLYDECNNSPLRREKNILEYLEWAKPFTSKVKQMRLHREDFEILKVIGRGAFG 30 40 50 60 70 80 100 110 120 130 140 150 pF1KB4 EVAVVKMKQTGQVYAMKIMNKWDMLKRGEVSCFREERDVLVNGDRRWITQLHFAFQDENY ::::::.:.. .:.::::.:::.::::.:..::::::::::::: .::: ::.::::.: NP_003 EVAVVKLKNADKVFAMKILNKWEMLKRAETACFREERDVLVNGDNKWITTLHYAFQDDNN 90 100 110 120 130 140 160 170 180 190 200 210 pF1KB4 LYLVMEYYVGGDLLTLLSKFGERIPAEMARFYLAEIVMAIDSVHRLGYVHRDIKPDNILL :::::.:::::::::::::: .:.: .::::::::.:.::::::.: ::::::::::::. NP_003 LYLVMDYYVGGDLLTLLSKFEDRLPEDMARFYLAEMVIAIDSVHQLHYVHRDIKPDNILM 150 160 170 180 190 200 220 230 240 250 260 270 pF1KB4 DRCGHIRLADFGSCLKLRADGTVRSLVAVGTPDYLSPEILQAVGGGPGTGSYGPECDWWA : :::::::::::::: ::::.: ::::::::.:::::::. : : ::::::::. NP_003 DMNGHIRLADFGSCLKLMEDGTVQSSVAVGTPDYISPEILQAMEDGKG--RYGPECDWWS 210 220 230 240 250 260 280 290 300 310 320 330 pF1KB4 LGVFAYEMFYGQTPFYADSTAETYGKIVHYKEHLSLPLVDEGVPEEARDFIQRLLCPPET ::: :::.::.:::::.: .::::::...::....: : :.:.:.:.::.: : NP_003 LGVCMYEMLYGETPFYAESLVETYGKIMNHKERFQFPAQVTDVSENAKDLIRRLICSREH 270 280 290 300 310 320 340 350 360 370 380 390 pF1KB4 RLGRGGAGDFRTHPFFFGLDWDGLRDSVPPFTPDFEGATDTCNFDLVEDGLTAMETLSDI :::..: ::. :::: :.:::..:. :. :. . ::: :::. .: : ::. NP_003 RLGQNGIEDFKKHPFFSGIDWDNIRNCEAPYIPEVSSPTDTSNFDVDDDCLKNSETMPPP 330 340 350 360 370 380 400 410 420 430 440 pF1KB4 REGAPLGVHLPFVGYSY--SCMALRDSE----VPGPTPMELEA--EQLLEPHVQAPSLEP . : : ::::::..: ::. : : . ::: ..:.. .. :. .. . . : NP_003 THTAFSGHHLPFVGFTYTSSCV-LSDRSCLRVTAGPTSLDLDVNVQRTLDNNLATEAYER 390 400 410 420 430 440 450 460 470 480 490 pF1KB4 SVSP-QDETAEVAVPAAVPAAEAEAEVTLRELQEALEEEVLTR------QSLSREMEAIR .. ..: :.. :. :.. :: . . :: ..:..:.: .: NP_003 RIKRLEQEKLELSRKLQ------ESTQTVQALQYSTVDGPLTASKDLEIKNLKEEIEKLR 450 460 470 480 490 500 500 510 520 530 540 550 pF1KB4 ---TDNQNFASQLREAEARNRDLEAHVRQLQ---ERMELLQAEGATAVTGVPSPRATDPP :..... .::.::.: ..:. ::.. .... :: : NP_003 KQVTESSHLEQQLEEANAVRQELDDAFRQIKAYEKQIKTLQQEREDLNKELVQASERLKN 510 520 530 540 550 560 560 570 580 590 600 610 pF1KB4 SHMAPRPWLWASARWWGQAPCTAATCCSLPGSLGLAYRRRFPCSCSPLFCLVPPPWAALG NP_003 QSKELKDAHCQRKLAMQEFMEINERLTELHTQKQKLARHVRDKEEEVDLVMQKVESLRQE 570 580 590 600 610 620 635 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 14:43:18 2016 done: Thu Nov 3 14:43:20 2016 Total Scan time: 12.830 Total Display time: 0.120 Function used was FASTA [36.3.4 Apr, 2011]