Result of FASTA (omim) for
pF1KB4307
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB4307, 334 aa
1>>>pF1KB4307 334 - 334 aa - 334 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 12.4093+/-0.000584; mu= -19.2353+/- 0.035
mean_var=772.7924+/-174.130, 0's: 0 Z-trim(115.3): 1375 B-trim: 0 in 0/54
Lambda= 0.046136
statistics sampled from 23855 (25710) to 23855 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.671), E-opt: 0.2 (0.301), width: 16
Scan time: 7.870
The best scores are: opt bits E(85289)
NP_002749 (OMIM: 601254) dual specificity mitogen- ( 334) 2229 164.2 3.6e-40
XP_011523328 (OMIM: 601254) PREDICTED: dual specif ( 337) 2201 162.3 1.3e-39
XP_011523327 (OMIM: 601254) PREDICTED: dual specif ( 345) 2199 162.2 1.5e-39
XP_006722038 (OMIM: 601254) PREDICTED: dual specif ( 278) 1853 139.0 1.1e-32
XP_005257573 (OMIM: 601254) PREDICTED: dual specif ( 278) 1853 139.0 1.1e-32
XP_011523329 (OMIM: 601254) PREDICTED: dual specif ( 278) 1853 139.0 1.1e-32
NP_001317379 (OMIM: 601254) dual specificity mitog ( 278) 1853 139.0 1.1e-32
NP_659731 (OMIM: 602315) dual specificity mitogen- ( 347) 1792 135.1 2.1e-31
XP_016880346 (OMIM: 602315) PREDICTED: dual specif ( 343) 1768 133.5 6.3e-31
NP_002747 (OMIM: 602315) dual specificity mitogen- ( 318) 1759 132.9 9.2e-31
XP_016880348 (OMIM: 602315) PREDICTED: dual specif ( 318) 1759 132.9 9.2e-31
NP_001303261 (OMIM: 602315) dual specificity mitog ( 318) 1759 132.9 9.2e-31
XP_005256780 (OMIM: 602315) PREDICTED: dual specif ( 318) 1759 132.9 9.2e-31
XP_011522261 (OMIM: 602315) PREDICTED: dual specif ( 318) 1759 132.9 9.2e-31
XP_016880347 (OMIM: 602315) PREDICTED: dual specif ( 318) 1759 132.9 9.2e-31
XP_011522260 (OMIM: 602315) PREDICTED: dual specif ( 298) 1286 101.3 2.7e-21
NP_003001 (OMIM: 601335) dual specificity mitogen- ( 399) 1200 95.8 1.7e-19
NP_001268364 (OMIM: 601335) dual specificity mitog ( 410) 1200 95.8 1.7e-19
XP_005256810 (OMIM: 601335) PREDICTED: dual specif ( 281) 1105 89.3 1.1e-17
XP_005256812 (OMIM: 601335) PREDICTED: dual specif ( 253) 973 80.4 4.5e-15
XP_011522279 (OMIM: 601335) PREDICTED: dual specif ( 253) 973 80.4 4.5e-15
XP_011522278 (OMIM: 601335) PREDICTED: dual specif ( 319) 952 79.1 1.4e-14
NP_660186 (OMIM: 603014) dual specificity mitogen- ( 419) 912 76.7 1e-13
NP_001284484 (OMIM: 603014) dual specificity mitog ( 435) 912 76.7 1e-13
NP_001193733 (OMIM: 602520) dual specificity mitog ( 412) 783 68.1 3.8e-11
NP_660143 (OMIM: 602520) dual specificity mitogen- ( 448) 783 68.1 4e-11
NP_001284485 (OMIM: 603014) dual specificity mitog ( 426) 765 66.9 8.9e-11
XP_006722863 (OMIM: 603014) PREDICTED: dual specif ( 442) 765 66.9 9.1e-11
NP_109587 (OMIM: 601263,615280) dual specificity m ( 400) 640 58.5 2.8e-08
XP_016882478 (OMIM: 601263,615280) PREDICTED: dual ( 512) 640 58.7 3.2e-08
XP_011520085 (OMIM: 163950,176872,615279) PREDICTE ( 371) 636 58.2 3.2e-08
NP_002746 (OMIM: 163950,176872,615279) dual specif ( 393) 636 58.2 3.3e-08
XP_006722862 (OMIM: 601263,615280) PREDICTED: dual ( 307) 528 50.9 4.2e-06
XP_016882479 (OMIM: 601263,615280) PREDICTED: dual ( 419) 528 51.1 5e-06
XP_016882480 (OMIM: 601263,615280) PREDICTED: dual ( 252) 518 50.1 5.9e-06
NP_001155038 (OMIM: 610005,617028) TRAF2 and NCK-i (1268) 495 49.6 4.3e-05
NP_001155037 (OMIM: 610005,617028) TRAF2 and NCK-i (1276) 495 49.6 4.3e-05
NP_001155036 (OMIM: 610005,617028) TRAF2 and NCK-i (1297) 495 49.6 4.3e-05
NP_001155035 (OMIM: 610005,617028) TRAF2 and NCK-i (1305) 495 49.6 4.4e-05
NP_001155034 (OMIM: 610005,617028) TRAF2 and NCK-i (1323) 495 49.6 4.4e-05
NP_001155033 (OMIM: 610005,617028) TRAF2 and NCK-i (1331) 495 49.6 4.4e-05
NP_001155032 (OMIM: 610005,617028) TRAF2 and NCK-i (1352) 495 49.6 4.5e-05
NP_055843 (OMIM: 610005,617028) TRAF2 and NCK-inte (1360) 495 49.6 4.5e-05
NP_005981 (OMIM: 603919) serine/threonine-protein ( 968) 490 49.1 4.6e-05
XP_011527322 (OMIM: 604965,614868) PREDICTED: seri ( 404) 479 47.8 4.7e-05
XP_016883522 (OMIM: 604965,614868) PREDICTED: seri ( 388) 477 47.7 5e-05
XP_005260588 (OMIM: 604965,614868) PREDICTED: seri ( 478) 479 47.9 5.1e-05
XP_005260587 (OMIM: 604965,614868) PREDICTED: seri ( 503) 479 47.9 5.3e-05
XP_005260590 (OMIM: 604965,614868) PREDICTED: seri ( 462) 477 47.8 5.5e-05
XP_016860864 (OMIM: 604666) PREDICTED: mitogen-act (1155) 488 49.1 5.6e-05
>>NP_002749 (OMIM: 601254) dual specificity mitogen-acti (334 aa)
initn: 2229 init1: 2229 opt: 2229 Z-score: 842.2 bits: 164.2 E(85289): 3.6e-40
Smith-Waterman score: 2229; 100.0% identity (100.0% similar) in 334 aa overlap (1-334:1-334)
10 20 30 40 50 60
pF1KB4 MSQSKGKKRNPGLKIPKEAFEQPQTSSTPPRDLDSKACISIGNQNFEVKADDLEPIMELG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MSQSKGKKRNPGLKIPKEAFEQPQTSSTPPRDLDSKACISIGNQNFEVKADDLEPIMELG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 RGAYGVVEKMRHVPSGQIMAVKRIRATVNSQEQKRLLMDLDISMRTVDCPFTVTFYGALF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 RGAYGVVEKMRHVPSGQIMAVKRIRATVNSQEQKRLLMDLDISMRTVDCPFTVTFYGALF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 REGDVWICMELMDTSLDKFYKQVIDKGQTIPEDILGKIAVSIVKALEHLHSKLSVIHRDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 REGDVWICMELMDTSLDKFYKQVIDKGQTIPEDILGKIAVSIVKALEHLHSKLSVIHRDV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 KPSNVLINALGQVKMCDFGISGYLVDSVAKTIDAGCKPYMAPERINPELNQKGYSVKSDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 KPSNVLINALGQVKMCDFGISGYLVDSVAKTIDAGCKPYMAPERINPELNQKGYSVKSDI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 WSLGITMIELAILRFPYDSWGTPFQQLKQVVEEPSPQLPADKFSAEFVDFTSQCLKKNSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 WSLGITMIELAILRFPYDSWGTPFQQLKQVVEEPSPQLPADKFSAEFVDFTSQCLKKNSK
250 260 270 280 290 300
310 320 330
pF1KB4 ERPTYPELMQHPFFTLHESKGTDVASFVKLILGD
::::::::::::::::::::::::::::::::::
NP_002 ERPTYPELMQHPFFTLHESKGTDVASFVKLILGD
310 320 330
>>XP_011523328 (OMIM: 601254) PREDICTED: dual specificit (337 aa)
initn: 2201 init1: 2201 opt: 2201 Z-score: 832.0 bits: 162.3 E(85289): 1.3e-39
Smith-Waterman score: 2201; 99.4% identity (100.0% similar) in 331 aa overlap (4-334:7-337)
10 20 30 40 50
pF1KB4 MSQSKGKKRNPGLKIPKEAFEQPQTSSTPPRDLDSKACISIGNQNFEVKADDLEPIM
..::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSHRAWAEGKKRNPGLKIPKEAFEQPQTSSTPPRDLDSKACISIGNQNFEVKADDLEPIM
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB4 ELGRGAYGVVEKMRHVPSGQIMAVKRIRATVNSQEQKRLLMDLDISMRTVDCPFTVTFYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELGRGAYGVVEKMRHVPSGQIMAVKRIRATVNSQEQKRLLMDLDISMRTVDCPFTVTFYG
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB4 ALFREGDVWICMELMDTSLDKFYKQVIDKGQTIPEDILGKIAVSIVKALEHLHSKLSVIH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALFREGDVWICMELMDTSLDKFYKQVIDKGQTIPEDILGKIAVSIVKALEHLHSKLSVIH
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB4 RDVKPSNVLINALGQVKMCDFGISGYLVDSVAKTIDAGCKPYMAPERINPELNQKGYSVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RDVKPSNVLINALGQVKMCDFGISGYLVDSVAKTIDAGCKPYMAPERINPELNQKGYSVK
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB4 SDIWSLGITMIELAILRFPYDSWGTPFQQLKQVVEEPSPQLPADKFSAEFVDFTSQCLKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SDIWSLGITMIELAILRFPYDSWGTPFQQLKQVVEEPSPQLPADKFSAEFVDFTSQCLKK
250 260 270 280 290 300
300 310 320 330
pF1KB4 NSKERPTYPELMQHPFFTLHESKGTDVASFVKLILGD
:::::::::::::::::::::::::::::::::::::
XP_011 NSKERPTYPELMQHPFFTLHESKGTDVASFVKLILGD
310 320 330
>>XP_011523327 (OMIM: 601254) PREDICTED: dual specificit (345 aa)
initn: 2199 init1: 2199 opt: 2199 Z-score: 831.2 bits: 162.2 E(85289): 1.5e-39
Smith-Waterman score: 2199; 100.0% identity (100.0% similar) in 329 aa overlap (6-334:17-345)
10 20 30 40
pF1KB4 MSQSKGKKRNPGLKIPKEAFEQPQTSSTPPRDLDSKACISIGNQNFEVK
::::::::::::::::::::::::::::::::::::::::::::
XP_011 MWSKSLKSLDVIFLQGGKKRNPGLKIPKEAFEQPQTSSTPPRDLDSKACISIGNQNFEVK
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB4 ADDLEPIMELGRGAYGVVEKMRHVPSGQIMAVKRIRATVNSQEQKRLLMDLDISMRTVDC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ADDLEPIMELGRGAYGVVEKMRHVPSGQIMAVKRIRATVNSQEQKRLLMDLDISMRTVDC
70 80 90 100 110 120
110 120 130 140 150 160
pF1KB4 PFTVTFYGALFREGDVWICMELMDTSLDKFYKQVIDKGQTIPEDILGKIAVSIVKALEHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PFTVTFYGALFREGDVWICMELMDTSLDKFYKQVIDKGQTIPEDILGKIAVSIVKALEHL
130 140 150 160 170 180
170 180 190 200 210 220
pF1KB4 HSKLSVIHRDVKPSNVLINALGQVKMCDFGISGYLVDSVAKTIDAGCKPYMAPERINPEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HSKLSVIHRDVKPSNVLINALGQVKMCDFGISGYLVDSVAKTIDAGCKPYMAPERINPEL
190 200 210 220 230 240
230 240 250 260 270 280
pF1KB4 NQKGYSVKSDIWSLGITMIELAILRFPYDSWGTPFQQLKQVVEEPSPQLPADKFSAEFVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NQKGYSVKSDIWSLGITMIELAILRFPYDSWGTPFQQLKQVVEEPSPQLPADKFSAEFVD
250 260 270 280 290 300
290 300 310 320 330
pF1KB4 FTSQCLKKNSKERPTYPELMQHPFFTLHESKGTDVASFVKLILGD
:::::::::::::::::::::::::::::::::::::::::::::
XP_011 FTSQCLKKNSKERPTYPELMQHPFFTLHESKGTDVASFVKLILGD
310 320 330 340
>>XP_006722038 (OMIM: 601254) PREDICTED: dual specificit (278 aa)
initn: 1853 init1: 1853 opt: 1853 Z-score: 707.7 bits: 139.0 E(85289): 1.1e-32
Smith-Waterman score: 1853; 100.0% identity (100.0% similar) in 278 aa overlap (57-334:1-278)
30 40 50 60 70 80
pF1KB4 STPPRDLDSKACISIGNQNFEVKADDLEPIMELGRGAYGVVEKMRHVPSGQIMAVKRIRA
::::::::::::::::::::::::::::::
XP_006 MELGRGAYGVVEKMRHVPSGQIMAVKRIRA
10 20 30
90 100 110 120 130 140
pF1KB4 TVNSQEQKRLLMDLDISMRTVDCPFTVTFYGALFREGDVWICMELMDTSLDKFYKQVIDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TVNSQEQKRLLMDLDISMRTVDCPFTVTFYGALFREGDVWICMELMDTSLDKFYKQVIDK
40 50 60 70 80 90
150 160 170 180 190 200
pF1KB4 GQTIPEDILGKIAVSIVKALEHLHSKLSVIHRDVKPSNVLINALGQVKMCDFGISGYLVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GQTIPEDILGKIAVSIVKALEHLHSKLSVIHRDVKPSNVLINALGQVKMCDFGISGYLVD
100 110 120 130 140 150
210 220 230 240 250 260
pF1KB4 SVAKTIDAGCKPYMAPERINPELNQKGYSVKSDIWSLGITMIELAILRFPYDSWGTPFQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SVAKTIDAGCKPYMAPERINPELNQKGYSVKSDIWSLGITMIELAILRFPYDSWGTPFQQ
160 170 180 190 200 210
270 280 290 300 310 320
pF1KB4 LKQVVEEPSPQLPADKFSAEFVDFTSQCLKKNSKERPTYPELMQHPFFTLHESKGTDVAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LKQVVEEPSPQLPADKFSAEFVDFTSQCLKKNSKERPTYPELMQHPFFTLHESKGTDVAS
220 230 240 250 260 270
330
pF1KB4 FVKLILGD
::::::::
XP_006 FVKLILGD
>>XP_005257573 (OMIM: 601254) PREDICTED: dual specificit (278 aa)
initn: 1853 init1: 1853 opt: 1853 Z-score: 707.7 bits: 139.0 E(85289): 1.1e-32
Smith-Waterman score: 1853; 100.0% identity (100.0% similar) in 278 aa overlap (57-334:1-278)
30 40 50 60 70 80
pF1KB4 STPPRDLDSKACISIGNQNFEVKADDLEPIMELGRGAYGVVEKMRHVPSGQIMAVKRIRA
::::::::::::::::::::::::::::::
XP_005 MELGRGAYGVVEKMRHVPSGQIMAVKRIRA
10 20 30
90 100 110 120 130 140
pF1KB4 TVNSQEQKRLLMDLDISMRTVDCPFTVTFYGALFREGDVWICMELMDTSLDKFYKQVIDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TVNSQEQKRLLMDLDISMRTVDCPFTVTFYGALFREGDVWICMELMDTSLDKFYKQVIDK
40 50 60 70 80 90
150 160 170 180 190 200
pF1KB4 GQTIPEDILGKIAVSIVKALEHLHSKLSVIHRDVKPSNVLINALGQVKMCDFGISGYLVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GQTIPEDILGKIAVSIVKALEHLHSKLSVIHRDVKPSNVLINALGQVKMCDFGISGYLVD
100 110 120 130 140 150
210 220 230 240 250 260
pF1KB4 SVAKTIDAGCKPYMAPERINPELNQKGYSVKSDIWSLGITMIELAILRFPYDSWGTPFQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SVAKTIDAGCKPYMAPERINPELNQKGYSVKSDIWSLGITMIELAILRFPYDSWGTPFQQ
160 170 180 190 200 210
270 280 290 300 310 320
pF1KB4 LKQVVEEPSPQLPADKFSAEFVDFTSQCLKKNSKERPTYPELMQHPFFTLHESKGTDVAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LKQVVEEPSPQLPADKFSAEFVDFTSQCLKKNSKERPTYPELMQHPFFTLHESKGTDVAS
220 230 240 250 260 270
330
pF1KB4 FVKLILGD
::::::::
XP_005 FVKLILGD
>>XP_011523329 (OMIM: 601254) PREDICTED: dual specificit (278 aa)
initn: 1853 init1: 1853 opt: 1853 Z-score: 707.7 bits: 139.0 E(85289): 1.1e-32
Smith-Waterman score: 1853; 100.0% identity (100.0% similar) in 278 aa overlap (57-334:1-278)
30 40 50 60 70 80
pF1KB4 STPPRDLDSKACISIGNQNFEVKADDLEPIMELGRGAYGVVEKMRHVPSGQIMAVKRIRA
::::::::::::::::::::::::::::::
XP_011 MELGRGAYGVVEKMRHVPSGQIMAVKRIRA
10 20 30
90 100 110 120 130 140
pF1KB4 TVNSQEQKRLLMDLDISMRTVDCPFTVTFYGALFREGDVWICMELMDTSLDKFYKQVIDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TVNSQEQKRLLMDLDISMRTVDCPFTVTFYGALFREGDVWICMELMDTSLDKFYKQVIDK
40 50 60 70 80 90
150 160 170 180 190 200
pF1KB4 GQTIPEDILGKIAVSIVKALEHLHSKLSVIHRDVKPSNVLINALGQVKMCDFGISGYLVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GQTIPEDILGKIAVSIVKALEHLHSKLSVIHRDVKPSNVLINALGQVKMCDFGISGYLVD
100 110 120 130 140 150
210 220 230 240 250 260
pF1KB4 SVAKTIDAGCKPYMAPERINPELNQKGYSVKSDIWSLGITMIELAILRFPYDSWGTPFQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SVAKTIDAGCKPYMAPERINPELNQKGYSVKSDIWSLGITMIELAILRFPYDSWGTPFQQ
160 170 180 190 200 210
270 280 290 300 310 320
pF1KB4 LKQVVEEPSPQLPADKFSAEFVDFTSQCLKKNSKERPTYPELMQHPFFTLHESKGTDVAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKQVVEEPSPQLPADKFSAEFVDFTSQCLKKNSKERPTYPELMQHPFFTLHESKGTDVAS
220 230 240 250 260 270
330
pF1KB4 FVKLILGD
::::::::
XP_011 FVKLILGD
>>NP_001317379 (OMIM: 601254) dual specificity mitogen-a (278 aa)
initn: 1853 init1: 1853 opt: 1853 Z-score: 707.7 bits: 139.0 E(85289): 1.1e-32
Smith-Waterman score: 1853; 100.0% identity (100.0% similar) in 278 aa overlap (57-334:1-278)
30 40 50 60 70 80
pF1KB4 STPPRDLDSKACISIGNQNFEVKADDLEPIMELGRGAYGVVEKMRHVPSGQIMAVKRIRA
::::::::::::::::::::::::::::::
NP_001 MELGRGAYGVVEKMRHVPSGQIMAVKRIRA
10 20 30
90 100 110 120 130 140
pF1KB4 TVNSQEQKRLLMDLDISMRTVDCPFTVTFYGALFREGDVWICMELMDTSLDKFYKQVIDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TVNSQEQKRLLMDLDISMRTVDCPFTVTFYGALFREGDVWICMELMDTSLDKFYKQVIDK
40 50 60 70 80 90
150 160 170 180 190 200
pF1KB4 GQTIPEDILGKIAVSIVKALEHLHSKLSVIHRDVKPSNVLINALGQVKMCDFGISGYLVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GQTIPEDILGKIAVSIVKALEHLHSKLSVIHRDVKPSNVLINALGQVKMCDFGISGYLVD
100 110 120 130 140 150
210 220 230 240 250 260
pF1KB4 SVAKTIDAGCKPYMAPERINPELNQKGYSVKSDIWSLGITMIELAILRFPYDSWGTPFQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SVAKTIDAGCKPYMAPERINPELNQKGYSVKSDIWSLGITMIELAILRFPYDSWGTPFQQ
160 170 180 190 200 210
270 280 290 300 310 320
pF1KB4 LKQVVEEPSPQLPADKFSAEFVDFTSQCLKKNSKERPTYPELMQHPFFTLHESKGTDVAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LKQVVEEPSPQLPADKFSAEFVDFTSQCLKKNSKERPTYPELMQHPFFTLHESKGTDVAS
220 230 240 250 260 270
330
pF1KB4 FVKLILGD
::::::::
NP_001 FVKLILGD
>>NP_659731 (OMIM: 602315) dual specificity mitogen-acti (347 aa)
initn: 1769 init1: 1769 opt: 1792 Z-score: 684.8 bits: 135.1 E(85289): 2.1e-31
Smith-Waterman score: 1792; 80.0% identity (91.6% similar) in 335 aa overlap (1-334:12-345)
10 20 30 40
pF1KB4 MSQSKGK-KRNPGLKIPKEAFEQPQTSSTPPRDLDSKACISIGNQNFEV
: ::::: ::. :.: . . : . ::::.:::.. :.::..::::
NP_659 MESPASSQPASMPQSKGKSKRKKDLRISCMS-KPPAPNPTPPRNLDSRTFITIGDRNFEV
10 20 30 40 50
50 60 70 80 90 100
pF1KB4 KADDLEPIMELGRGAYGVVEKMRHVPSGQIMAVKRIRATVNSQEQKRLLMDLDISMRTVD
.:::: : ::::::::::::.::. :: :::::::::::::::::::::::::.:::::
NP_659 EADDLVTISELGRGAYGVVEKVRHAQSGTIMAVKRIRATVNSQEQKRLLMDLDINMRTVD
60 70 80 90 100 110
110 120 130 140 150 160
pF1KB4 CPFTVTFYGALFREGDVWICMELMDTSLDKFYKQVIDKGQTIPEDILGKIAVSIVKALEH
: .:::::::::::::::::::::::::::::..:.::..::::::::.::::::.::::
NP_659 CFYTVTFYGALFREGDVWICMELMDTSLDKFYRKVLDKNMTIPEDILGEIAVSIVRALEH
120 130 140 150 160 170
170 180 190 200 210 220
pF1KB4 LHSKLSVIHRDVKPSNVLINALGQVKMCDFGISGYLVDSVAKTIDAGCKPYMAPERINPE
:::::::::::::::::::: :.:::::::::::::::::::.::::::::::::::::
NP_659 LHSKLSVIHRDVKPSNVLINKEGHVKMCDFGISGYLVDSVAKTMDAGCKPYMAPERINPE
180 190 200 210 220 230
230 240 250 260 270 280
pF1KB4 LNQKGYSVKSDIWSLGITMIELAILRFPYDSWGTPFQQLKQVVEEPSPQLPADKFSAEFV
::::::.::::.:::::::::.:::::::.:::::::::::::::::::::::.:: :::
NP_659 LNQKGYNVKSDVWSLGITMIEMAILRFPYESWGTPFQQLKQVVEEPSPQLPADRFSPEFV
240 250 260 270 280 290
290 300 310 320 330
pF1KB4 DFTSQCLKKNSKERPTYPELMQHPFFTLHESKGTDVASFVKLILGD
:::.:::.:: :: .: :::.:::::::..: ::.:.::: :::.
NP_659 DFTAQCLRKNPAERMSYLELMEHPFFTLHKTKKTDIAAFVKEILGEDS
300 310 320 330 340
>>XP_016880346 (OMIM: 602315) PREDICTED: dual specificit (343 aa)
initn: 1759 init1: 1759 opt: 1768 Z-score: 676.2 bits: 133.5 E(85289): 6.3e-31
Smith-Waterman score: 1768; 80.0% identity (91.8% similar) in 330 aa overlap (6-334:13-341)
10 20 30 40 50
pF1KB4 MSQSKGK-KRNPGLKIPKEAFEQPQTSSTPPRDLDSKACISIGNQNFEVKADD
:: ::. :.: . . : . ::::.:::.. :.::..::::.:::
XP_016 MNSPSLLPQRDPGKSKRKKDLRISCMS-KPPAPNPTPPRNLDSRTFITIGDRNFEVEADD
10 20 30 40 50
60 70 80 90 100 110
pF1KB4 LEPIMELGRGAYGVVEKMRHVPSGQIMAVKRIRATVNSQEQKRLLMDLDISMRTVDCPFT
: : ::::::::::::.::. :: :::::::::::::::::::::::::.:::::: .:
XP_016 LVTISELGRGAYGVVEKVRHAQSGTIMAVKRIRATVNSQEQKRLLMDLDINMRTVDCFYT
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB4 VTFYGALFREGDVWICMELMDTSLDKFYKQVIDKGQTIPEDILGKIAVSIVKALEHLHSK
::::::::::::::::::::::::::::..:.::..::::::::.::::::.::::::::
XP_016 VTFYGALFREGDVWICMELMDTSLDKFYRKVLDKNMTIPEDILGEIAVSIVRALEHLHSK
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB4 LSVIHRDVKPSNVLINALGQVKMCDFGISGYLVDSVAKTIDAGCKPYMAPERINPELNQK
:::::::::::::::: :.:::::::::::::::::::.::::::::::::::::::::
XP_016 LSVIHRDVKPSNVLINKEGHVKMCDFGISGYLVDSVAKTMDAGCKPYMAPERINPELNQK
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB4 GYSVKSDIWSLGITMIELAILRFPYDSWGTPFQQLKQVVEEPSPQLPADKFSAEFVDFTS
::.::::.:::::::::.:::::::.:::::::::::::::::::::::.:: ::::::.
XP_016 GYNVKSDVWSLGITMIEMAILRFPYESWGTPFQQLKQVVEEPSPQLPADRFSPEFVDFTA
240 250 260 270 280 290
300 310 320 330
pF1KB4 QCLKKNSKERPTYPELMQHPFFTLHESKGTDVASFVKLILGD
:::.:: :: .: :::.:::::::..: ::.:.::: :::.
XP_016 QCLRKNPAERMSYLELMEHPFFTLHKTKKTDIAAFVKEILGEDS
300 310 320 330 340
>>NP_002747 (OMIM: 602315) dual specificity mitogen-acti (318 aa)
initn: 1751 init1: 1751 opt: 1759 Z-score: 673.3 bits: 132.9 E(85289): 9.2e-31
Smith-Waterman score: 1759; 82.7% identity (93.9% similar) in 312 aa overlap (23-334:5-316)
10 20 30 40 50 60
pF1KB4 MSQSKGKKRNPGLKIPKEAFEQPQTSSTPPRDLDSKACISIGNQNFEVKADDLEPIMELG
: . ::::.:::.. :.::..::::.:::: : :::
NP_002 MSKPPAPNPTPPRNLDSRTFITIGDRNFEVEADDLVTISELG
10 20 30 40
70 80 90 100 110 120
pF1KB4 RGAYGVVEKMRHVPSGQIMAVKRIRATVNSQEQKRLLMDLDISMRTVDCPFTVTFYGALF
:::::::::.::. :: :::::::::::::::::::::::::.:::::: .:::::::::
NP_002 RGAYGVVEKVRHAQSGTIMAVKRIRATVNSQEQKRLLMDLDINMRTVDCFYTVTFYGALF
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB4 REGDVWICMELMDTSLDKFYKQVIDKGQTIPEDILGKIAVSIVKALEHLHSKLSVIHRDV
::::::::::::::::::::..:.::..::::::::.::::::.::::::::::::::::
NP_002 REGDVWICMELMDTSLDKFYRKVLDKNMTIPEDILGEIAVSIVRALEHLHSKLSVIHRDV
110 120 130 140 150 160
190 200 210 220 230 240
pF1KB4 KPSNVLINALGQVKMCDFGISGYLVDSVAKTIDAGCKPYMAPERINPELNQKGYSVKSDI
:::::::: :.:::::::::::::::::::.::::::::::::::::::::::.::::.
NP_002 KPSNVLINKEGHVKMCDFGISGYLVDSVAKTMDAGCKPYMAPERINPELNQKGYNVKSDV
170 180 190 200 210 220
250 260 270 280 290 300
pF1KB4 WSLGITMIELAILRFPYDSWGTPFQQLKQVVEEPSPQLPADKFSAEFVDFTSQCLKKNSK
:::::::::.:::::::.:::::::::::::::::::::::.:: ::::::.:::.::
NP_002 WSLGITMIEMAILRFPYESWGTPFQQLKQVVEEPSPQLPADRFSPEFVDFTAQCLRKNPA
230 240 250 260 270 280
310 320 330
pF1KB4 ERPTYPELMQHPFFTLHESKGTDVASFVKLILGD
:: .: :::.:::::::..: ::.:.::: :::.
NP_002 ERMSYLELMEHPFFTLHKTKKTDIAAFVKEILGEDS
290 300 310
334 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 14:43:55 2016 done: Thu Nov 3 14:43:56 2016
Total Scan time: 7.870 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]