FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB4343, 364 aa 1>>>pF1KB4343 364 - 364 aa - 364 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.8676+/-0.000503; mu= 11.1400+/- 0.031 mean_var=315.2064+/-62.915, 0's: 0 Z-trim(118.7): 1756 B-trim: 106 in 1/52 Lambda= 0.072240 statistics sampled from 29667 (31831) to 29667 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.726), E-opt: 0.2 (0.373), width: 16 Scan time: 8.920 The best scores are: opt bits E(85289) NP_057173 (OMIM: 616702) zinc finger protein 589 [ ( 364) 2568 281.5 2e-75 XP_016862064 (OMIM: 616702) PREDICTED: zinc finger ( 363) 2551 279.8 6.9e-75 XP_016862066 (OMIM: 616702) PREDICTED: zinc finger ( 362) 2327 256.4 7.3e-68 XP_016862065 (OMIM: 616702) PREDICTED: zinc finger ( 362) 2327 256.4 7.3e-68 XP_016862067 (OMIM: 616702) PREDICTED: zinc finger ( 361) 2310 254.6 2.5e-67 XP_016862068 (OMIM: 616702) PREDICTED: zinc finger ( 361) 2310 254.6 2.5e-67 NP_064612 (OMIM: 609760) histone-lysine N-methyltr ( 894) 649 82.2 5.1e-15 NP_001297143 (OMIM: 609760) histone-lysine N-methy ( 894) 647 82.0 5.9e-15 NP_001269937 (OMIM: 604075) zinc finger protein 13 ( 559) 612 78.0 5.8e-14 XP_016883547 (OMIM: 604075) PREDICTED: zinc finger ( 590) 612 78.0 6e-14 XP_016883545 (OMIM: 604075) PREDICTED: zinc finger ( 591) 612 78.0 6e-14 NP_001269933 (OMIM: 604075) zinc finger protein 13 ( 591) 612 78.0 6e-14 XP_016883544 (OMIM: 604075) PREDICTED: zinc finger ( 591) 612 78.0 6e-14 XP_016883546 (OMIM: 604075) PREDICTED: zinc finger ( 591) 612 78.0 6e-14 NP_001269932 (OMIM: 604075) zinc finger protein 13 ( 591) 612 78.0 6e-14 NP_001269934 (OMIM: 604075) zinc finger protein 13 ( 635) 612 78.1 6.2e-14 XP_011527642 (OMIM: 604075) PREDICTED: zinc finger ( 636) 612 78.1 6.2e-14 NP_001269924 (OMIM: 604075) zinc finger protein 13 ( 653) 612 78.1 6.3e-14 NP_001076799 (OMIM: 604075) zinc finger protein 13 ( 653) 612 78.1 6.3e-14 XP_016883543 (OMIM: 604075) PREDICTED: zinc finger ( 653) 612 78.1 6.3e-14 NP_003425 (OMIM: 604075) zinc finger protein 133 i ( 653) 612 78.1 6.3e-14 XP_016883541 (OMIM: 604075) PREDICTED: zinc finger ( 653) 612 78.1 6.3e-14 XP_016883538 (OMIM: 604075) PREDICTED: zinc finger ( 653) 612 78.1 6.3e-14 XP_016883542 (OMIM: 604075) PREDICTED: zinc finger ( 653) 612 78.1 6.3e-14 XP_016883539 (OMIM: 604075) PREDICTED: zinc finger ( 653) 612 78.1 6.3e-14 XP_016883540 (OMIM: 604075) PREDICTED: zinc finger ( 653) 612 78.1 6.3e-14 XP_016883536 (OMIM: 604075) PREDICTED: zinc finger ( 654) 612 78.1 6.3e-14 XP_005260877 (OMIM: 604075) PREDICTED: zinc finger ( 654) 612 78.1 6.3e-14 XP_016883534 (OMIM: 604075) PREDICTED: zinc finger ( 654) 612 78.1 6.3e-14 XP_011527639 (OMIM: 604075) PREDICTED: zinc finger ( 654) 612 78.1 6.3e-14 XP_005260876 (OMIM: 604075) PREDICTED: zinc finger ( 654) 612 78.1 6.3e-14 XP_016883533 (OMIM: 604075) PREDICTED: zinc finger ( 654) 612 78.1 6.3e-14 XP_011527638 (OMIM: 604075) PREDICTED: zinc finger ( 654) 612 78.1 6.3e-14 NP_001269930 (OMIM: 604075) zinc finger protein 13 ( 654) 612 78.1 6.3e-14 NP_001269927 (OMIM: 604075) zinc finger protein 13 ( 654) 612 78.1 6.3e-14 XP_016883535 (OMIM: 604075) PREDICTED: zinc finger ( 654) 612 78.1 6.3e-14 NP_001269928 (OMIM: 604075) zinc finger protein 13 ( 654) 612 78.1 6.3e-14 NP_001269929 (OMIM: 604075) zinc finger protein 13 ( 654) 612 78.1 6.3e-14 XP_016883537 (OMIM: 604075) PREDICTED: zinc finger ( 654) 612 78.1 6.3e-14 NP_001269926 (OMIM: 604075) zinc finger protein 13 ( 654) 612 78.1 6.3e-14 XP_011527640 (OMIM: 604075) PREDICTED: zinc finger ( 654) 612 78.1 6.3e-14 XP_011527641 (OMIM: 604075) PREDICTED: zinc finger ( 654) 612 78.1 6.3e-14 XP_016883532 (OMIM: 604075) PREDICTED: zinc finger ( 656) 612 78.1 6.3e-14 XP_016883530 (OMIM: 604075) PREDICTED: zinc finger ( 657) 612 78.1 6.3e-14 NP_001269931 (OMIM: 604075) zinc finger protein 13 ( 657) 612 78.1 6.3e-14 XP_016883531 (OMIM: 604075) PREDICTED: zinc finger ( 657) 612 78.1 6.3e-14 NP_001269935 (OMIM: 604075) zinc finger protein 13 ( 661) 612 78.1 6.3e-14 NP_001269936 (OMIM: 604075) zinc finger protein 13 ( 667) 612 78.1 6.3e-14 NP_001269925 (OMIM: 604075) zinc finger protein 13 ( 671) 612 78.1 6.4e-14 XP_011526673 (OMIM: 611811) PREDICTED: zinc finger ( 476) 606 77.2 8.3e-14 >>NP_057173 (OMIM: 616702) zinc finger protein 589 [Homo (364 aa) initn: 2568 init1: 2568 opt: 2568 Z-score: 1475.0 bits: 281.5 E(85289): 2e-75 Smith-Waterman score: 2568; 100.0% identity (100.0% similar) in 364 aa overlap (1-364:1-364) 10 20 30 40 50 60 pF1KB4 MWAPREQLLGWTAEALPAKDSAWPWEEKPRYLGPVTFEDVAVLFTEAEWKRLSLEQRNLY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 MWAPREQLLGWTAEALPAKDSAWPWEEKPRYLGPVTFEDVAVLFTEAEWKRLSLEQRNLY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 KEVMLENLRNLVSLAESKPEVHTCPSCPLAFGSQQFLSQDELHNHPIPGFHAGNQLHPGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 KEVMLENLRNLVSLAESKPEVHTCPSCPLAFGSQQFLSQDELHNHPIPGFHAGNQLHPGN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 PCPEDQPQSQHPSDKNHRGAEAEDQRVEGGVRPLFWSTNERGALVGFSSLFQRPPISSWG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 PCPEDQPQSQHPSDKNHRGAEAEDQRVEGGVRPLFWSTNERGALVGFSSLFQRPPISSWG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 GNRILEIQLSPAQNASSEEVDRISKRAETPGFGAVTFGECALAFNQKSNLFRQKAVTAEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 GNRILEIQLSPAQNASSEEVDRISKRAETPGFGAVTFGECALAFNQKSNLFRQKAVTAEK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 SSDKRQSQVCRECGRGFSRKSQLIIHQRTHTGEKPYVCGECGRGFIVESVLRNHLSTHSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 SSDKRQSQVCRECGRGFSRKSQLIIHQRTHTGEKPYVCGECGRGFIVESVLRNHLSTHSG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 EKPYVCSHCGRGFSCKPYLIRHQRTHTREKSFMCTVCGRGFREKSELIKHQRIHTGDKPY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 EKPYVCSHCGRGFSCKPYLIRHQRTHTREKSFMCTVCGRGFREKSELIKHQRIHTGDKPY 310 320 330 340 350 360 pF1KB4 VCRD :::: NP_057 VCRD >>XP_016862064 (OMIM: 616702) PREDICTED: zinc finger pro (363 aa) initn: 2549 init1: 2056 opt: 2551 Z-score: 1465.5 bits: 279.8 E(85289): 6.9e-75 Smith-Waterman score: 2551; 99.7% identity (99.7% similar) in 364 aa overlap (1-364:1-363) 10 20 30 40 50 60 pF1KB4 MWAPREQLLGWTAEALPAKDSAWPWEEKPRYLGPVTFEDVAVLFTEAEWKRLSLEQRNLY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MWAPREQLLGWTAEALPAKDSAWPWEEKPRYLGPVTFEDVAVLFTEAEWKRLSLEQRNLY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 KEVMLENLRNLVSLAESKPEVHTCPSCPLAFGSQQFLSQDELHNHPIPGFHAGNQLHPGN :::::::::::::: ::::::::::::::::::::::::::::::::::::::::::::: XP_016 KEVMLENLRNLVSL-ESKPEVHTCPSCPLAFGSQQFLSQDELHNHPIPGFHAGNQLHPGN 70 80 90 100 110 130 140 150 160 170 180 pF1KB4 PCPEDQPQSQHPSDKNHRGAEAEDQRVEGGVRPLFWSTNERGALVGFSSLFQRPPISSWG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PCPEDQPQSQHPSDKNHRGAEAEDQRVEGGVRPLFWSTNERGALVGFSSLFQRPPISSWG 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB4 GNRILEIQLSPAQNASSEEVDRISKRAETPGFGAVTFGECALAFNQKSNLFRQKAVTAEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GNRILEIQLSPAQNASSEEVDRISKRAETPGFGAVTFGECALAFNQKSNLFRQKAVTAEK 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB4 SSDKRQSQVCRECGRGFSRKSQLIIHQRTHTGEKPYVCGECGRGFIVESVLRNHLSTHSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSDKRQSQVCRECGRGFSRKSQLIIHQRTHTGEKPYVCGECGRGFIVESVLRNHLSTHSG 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB4 EKPYVCSHCGRGFSCKPYLIRHQRTHTREKSFMCTVCGRGFREKSELIKHQRIHTGDKPY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EKPYVCSHCGRGFSCKPYLIRHQRTHTREKSFMCTVCGRGFREKSELIKHQRIHTGDKPY 300 310 320 330 340 350 pF1KB4 VCRD :::: XP_016 VCRD 360 >>XP_016862066 (OMIM: 616702) PREDICTED: zinc finger pro (362 aa) initn: 2327 init1: 2327 opt: 2327 Z-score: 1339.3 bits: 256.4 E(85289): 7.3e-68 Smith-Waterman score: 2327; 99.7% identity (100.0% similar) in 333 aa overlap (32-364:30-362) 10 20 30 40 50 60 pF1KB4 WAPREQLLGWTAEALPAKDSAWPWEEKPRYLGPVTFEDVAVLFTEAEWKRLSLEQRNLYK .::::::::::::::::::::::::::::: XP_016 MIDFQMLNQLCRTIINPSVIPCLKYCGDQIGPVTFEDVAVLFTEAEWKRLSLEQRNLYK 10 20 30 40 50 70 80 90 100 110 120 pF1KB4 EVMLENLRNLVSLAESKPEVHTCPSCPLAFGSQQFLSQDELHNHPIPGFHAGNQLHPGNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EVMLENLRNLVSLAESKPEVHTCPSCPLAFGSQQFLSQDELHNHPIPGFHAGNQLHPGNP 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB4 CPEDQPQSQHPSDKNHRGAEAEDQRVEGGVRPLFWSTNERGALVGFSSLFQRPPISSWGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CPEDQPQSQHPSDKNHRGAEAEDQRVEGGVRPLFWSTNERGALVGFSSLFQRPPISSWGG 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB4 NRILEIQLSPAQNASSEEVDRISKRAETPGFGAVTFGECALAFNQKSNLFRQKAVTAEKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NRILEIQLSPAQNASSEEVDRISKRAETPGFGAVTFGECALAFNQKSNLFRQKAVTAEKS 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB4 SDKRQSQVCRECGRGFSRKSQLIIHQRTHTGEKPYVCGECGRGFIVESVLRNHLSTHSGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SDKRQSQVCRECGRGFSRKSQLIIHQRTHTGEKPYVCGECGRGFIVESVLRNHLSTHSGE 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB4 KPYVCSHCGRGFSCKPYLIRHQRTHTREKSFMCTVCGRGFREKSELIKHQRIHTGDKPYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KPYVCSHCGRGFSCKPYLIRHQRTHTREKSFMCTVCGRGFREKSELIKHQRIHTGDKPYV 300 310 320 330 340 350 pF1KB4 CRD ::: XP_016 CRD 360 >>XP_016862065 (OMIM: 616702) PREDICTED: zinc finger pro (362 aa) initn: 2327 init1: 2327 opt: 2327 Z-score: 1339.3 bits: 256.4 E(85289): 7.3e-68 Smith-Waterman score: 2327; 99.7% identity (100.0% similar) in 333 aa overlap (32-364:30-362) 10 20 30 40 50 60 pF1KB4 WAPREQLLGWTAEALPAKDSAWPWEEKPRYLGPVTFEDVAVLFTEAEWKRLSLEQRNLYK .::::::::::::::::::::::::::::: XP_016 MIDFQMLNQLCRTIINPSVIPCLKYCGDQIGPVTFEDVAVLFTEAEWKRLSLEQRNLYK 10 20 30 40 50 70 80 90 100 110 120 pF1KB4 EVMLENLRNLVSLAESKPEVHTCPSCPLAFGSQQFLSQDELHNHPIPGFHAGNQLHPGNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EVMLENLRNLVSLAESKPEVHTCPSCPLAFGSQQFLSQDELHNHPIPGFHAGNQLHPGNP 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB4 CPEDQPQSQHPSDKNHRGAEAEDQRVEGGVRPLFWSTNERGALVGFSSLFQRPPISSWGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CPEDQPQSQHPSDKNHRGAEAEDQRVEGGVRPLFWSTNERGALVGFSSLFQRPPISSWGG 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB4 NRILEIQLSPAQNASSEEVDRISKRAETPGFGAVTFGECALAFNQKSNLFRQKAVTAEKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NRILEIQLSPAQNASSEEVDRISKRAETPGFGAVTFGECALAFNQKSNLFRQKAVTAEKS 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB4 SDKRQSQVCRECGRGFSRKSQLIIHQRTHTGEKPYVCGECGRGFIVESVLRNHLSTHSGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SDKRQSQVCRECGRGFSRKSQLIIHQRTHTGEKPYVCGECGRGFIVESVLRNHLSTHSGE 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB4 KPYVCSHCGRGFSCKPYLIRHQRTHTREKSFMCTVCGRGFREKSELIKHQRIHTGDKPYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KPYVCSHCGRGFSCKPYLIRHQRTHTREKSFMCTVCGRGFREKSELIKHQRIHTGDKPYV 300 310 320 330 340 350 pF1KB4 CRD ::: XP_016 CRD 360 >>XP_016862067 (OMIM: 616702) PREDICTED: zinc finger pro (361 aa) initn: 2308 init1: 2056 opt: 2310 Z-score: 1329.7 bits: 254.6 E(85289): 2.5e-67 Smith-Waterman score: 2310; 99.4% identity (99.7% similar) in 333 aa overlap (32-364:30-361) 10 20 30 40 50 60 pF1KB4 WAPREQLLGWTAEALPAKDSAWPWEEKPRYLGPVTFEDVAVLFTEAEWKRLSLEQRNLYK .::::::::::::::::::::::::::::: XP_016 MIDFQMLNQLCRTIINPSVIPCLKYCGDQIGPVTFEDVAVLFTEAEWKRLSLEQRNLYK 10 20 30 40 50 70 80 90 100 110 120 pF1KB4 EVMLENLRNLVSLAESKPEVHTCPSCPLAFGSQQFLSQDELHNHPIPGFHAGNQLHPGNP ::::::::::::: :::::::::::::::::::::::::::::::::::::::::::::: XP_016 EVMLENLRNLVSL-ESKPEVHTCPSCPLAFGSQQFLSQDELHNHPIPGFHAGNQLHPGNP 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB4 CPEDQPQSQHPSDKNHRGAEAEDQRVEGGVRPLFWSTNERGALVGFSSLFQRPPISSWGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CPEDQPQSQHPSDKNHRGAEAEDQRVEGGVRPLFWSTNERGALVGFSSLFQRPPISSWGG 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB4 NRILEIQLSPAQNASSEEVDRISKRAETPGFGAVTFGECALAFNQKSNLFRQKAVTAEKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NRILEIQLSPAQNASSEEVDRISKRAETPGFGAVTFGECALAFNQKSNLFRQKAVTAEKS 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB4 SDKRQSQVCRECGRGFSRKSQLIIHQRTHTGEKPYVCGECGRGFIVESVLRNHLSTHSGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SDKRQSQVCRECGRGFSRKSQLIIHQRTHTGEKPYVCGECGRGFIVESVLRNHLSTHSGE 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB4 KPYVCSHCGRGFSCKPYLIRHQRTHTREKSFMCTVCGRGFREKSELIKHQRIHTGDKPYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KPYVCSHCGRGFSCKPYLIRHQRTHTREKSFMCTVCGRGFREKSELIKHQRIHTGDKPYV 300 310 320 330 340 350 pF1KB4 CRD ::: XP_016 CRD 360 >>XP_016862068 (OMIM: 616702) PREDICTED: zinc finger pro (361 aa) initn: 2308 init1: 2056 opt: 2310 Z-score: 1329.7 bits: 254.6 E(85289): 2.5e-67 Smith-Waterman score: 2310; 99.4% identity (99.7% similar) in 333 aa overlap (32-364:30-361) 10 20 30 40 50 60 pF1KB4 WAPREQLLGWTAEALPAKDSAWPWEEKPRYLGPVTFEDVAVLFTEAEWKRLSLEQRNLYK .::::::::::::::::::::::::::::: XP_016 MIDFQMLNQLCRTIINPSVIPCLKYCGDQIGPVTFEDVAVLFTEAEWKRLSLEQRNLYK 10 20 30 40 50 70 80 90 100 110 120 pF1KB4 EVMLENLRNLVSLAESKPEVHTCPSCPLAFGSQQFLSQDELHNHPIPGFHAGNQLHPGNP ::::::::::::: :::::::::::::::::::::::::::::::::::::::::::::: XP_016 EVMLENLRNLVSL-ESKPEVHTCPSCPLAFGSQQFLSQDELHNHPIPGFHAGNQLHPGNP 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB4 CPEDQPQSQHPSDKNHRGAEAEDQRVEGGVRPLFWSTNERGALVGFSSLFQRPPISSWGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CPEDQPQSQHPSDKNHRGAEAEDQRVEGGVRPLFWSTNERGALVGFSSLFQRPPISSWGG 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB4 NRILEIQLSPAQNASSEEVDRISKRAETPGFGAVTFGECALAFNQKSNLFRQKAVTAEKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NRILEIQLSPAQNASSEEVDRISKRAETPGFGAVTFGECALAFNQKSNLFRQKAVTAEKS 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB4 SDKRQSQVCRECGRGFSRKSQLIIHQRTHTGEKPYVCGECGRGFIVESVLRNHLSTHSGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SDKRQSQVCRECGRGFSRKSQLIIHQRTHTGEKPYVCGECGRGFIVESVLRNHLSTHSGE 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB4 KPYVCSHCGRGFSCKPYLIRHQRTHTREKSFMCTVCGRGFREKSELIKHQRIHTGDKPYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KPYVCSHCGRGFSCKPYLIRHQRTHTREKSFMCTVCGRGFREKSELIKHQRIHTGDKPYV 300 310 320 330 340 350 pF1KB4 CRD ::: XP_016 CRD 360 >>NP_064612 (OMIM: 609760) histone-lysine N-methyltransf (894 aa) initn: 5786 init1: 628 opt: 649 Z-score: 390.7 bits: 82.2 E(85289): 5.1e-15 Smith-Waterman score: 653; 63.3% identity (80.3% similar) in 147 aa overlap (219-364:724-864) 190 200 210 220 230 240 pF1KB4 LSPAQNASSEEVDRISKRAETPGFGAVTFGECALAFNQKSNLFR-QKAVTAEKSSDKRQS ::. .:..::.:.: :.. :.:: NP_064 CRECGRGFSWQSVLLTHQRTHTGEKPYVCRECGRGFSNKSHLLRHQRTHTGEKP------ 700 710 720 730 740 250 260 270 280 290 300 pF1KB4 QVCRECGRGFSRKSQLIIHQRTHTGEKPYVCGECGRGFIVESVLRNHLSTHSGEKPYVCS ::::::::: ::.:. ::::::::::::: :::::: .: : .: ::.::::::: NP_064 YVCRECGRGFRDKSHLLRHQRTHTGEKPYVCRECGRGFRDKSNLLSHQRTHTGEKPYVCR 750 760 770 780 790 800 310 320 330 340 350 360 pF1KB4 HCGRGFSCKPYLIRHQRTHTREKSFMCTVCGRGFREKSELIKHQRIHTGDKPYVCRD .:::::: : .:.::::::: :: ..: ::::::.::.:..::: :::.::::::. NP_064 ECGRGFSNKSHLLRHQRTHTGEKPYVCRECGRGFRNKSHLLRHQRTHTGEKPYVCRECGR 810 820 830 840 850 860 NP_064 GFSDRSSLCYHQRTHTGEKPYVCREDE 870 880 890 >-- initn: 5786 init1: 628 opt: 649 Z-score: 390.7 bits: 82.2 E(85289): 5.1e-15 Smith-Waterman score: 864; 45.7% identity (67.2% similar) in 293 aa overlap (79-364:385-668) 50 60 70 80 90 100 pF1KB4 WKRLSLEQRNLYKEVMLENLRNLVSLAESKPEVHTCPSCPLAFGSQQFLSQDELHNHP-- ::.: :::: :::.::.:::: .:: NP_064 VWYGDEYGQELGIKWGSKWKKELMAGREPKPEIHPCPSCCLAFSSQKFLSQHVERNHSSQ 360 370 380 390 400 410 110 120 130 140 150 160 pF1KB4 -IPGFHAGNQLHPGNPCPEDQPQSQHPSDKNHRGAEAEDQRVEGGVRPLFWSTNERGALV .:: : . :.: :::: :: : :. : . :. ... :... . : :.: NP_064 NFPGPSARKLLQPENPCPGDQNQEQQYPDPHSRNDKTKGQEIKERSKLL----NKRTWQR 420 430 440 450 460 470 170 180 190 200 210 220 pF1KB4 GFSSLFQRPPISSWG----GNRILEIQLSPAQNASSEEVDRISKRAETPGFGAVTFGECA .: :. :: .. : :.::.: . .:... .. .. . .. : .:::. NP_064 EISRAFSSPPKGQMGSCRVGKRIMEEESRTGQKVNPGNTGKLFVGVGISRIAKVKYGECG 480 490 500 510 520 530 230 240 250 260 270 280 pF1KB4 LAFNQKSNLFRQKAVTAEKSSDKRQSQVCRECGRGFSRKSQLIIHQRTHTGEKPYVCGEC .:. ::.. .: ... .. :::::::::: ::.:.:::: ::::::::: :: NP_064 QGFSVKSDV-----ITHQRTHTGEKLYVCRECGRGFSWKSHLLIHQRIHTGEKPYVCREC 540 550 560 570 580 290 300 310 320 330 340 pF1KB4 GRGFIVESVLRNHLSTHSGEKPYVCSHCGRGFSCKPYLIRHQRTHTREKSFMCTVCGRGF :::: .::: .: ::.::::::: .:::::: . :. ::: :: :: ..: ::::: NP_064 GRGFSWQSVLLTHQRTHTGEKPYVCRECGRGFSRQSVLLTHQRRHTGEKPYVCRECGRGF 590 600 610 620 630 640 350 360 pF1KB4 REKSELIKHQRIHTGDKPYVCRD ..: :. ::: :::.::::::. NP_064 SRQSVLLTHQRRHTGEKPYVCRECGRGFSWQSVLLTHQRTHTGEKPYVCRECGRGFSWQS 650 660 670 680 690 700 >>NP_001297143 (OMIM: 609760) histone-lysine N-methyltra (894 aa) initn: 5786 init1: 626 opt: 647 Z-score: 389.5 bits: 82.0 E(85289): 5.9e-15 Smith-Waterman score: 653; 63.3% identity (80.3% similar) in 147 aa overlap (219-364:724-864) 190 200 210 220 230 240 pF1KB4 LSPAQNASSEEVDRISKRAETPGFGAVTFGECALAFNQKSNLFR-QKAVTAEKSSDKRQS ::. .:..::.:.: :.. :.:: NP_001 CRECGRGFSWQSVLLTHQRTHTGEKPYVCRECGRGFSNKSHLLRHQRTHTGEKP------ 700 710 720 730 740 250 260 270 280 290 300 pF1KB4 QVCRECGRGFSRKSQLIIHQRTHTGEKPYVCGECGRGFIVESVLRNHLSTHSGEKPYVCS ::::::::: ::.:. ::::::::::::: :::::: .: : .: ::.::::::: NP_001 YVCRECGRGFRDKSHLLRHQRTHTGEKPYVCRECGRGFRDKSNLLSHQRTHTGEKPYVCR 750 760 770 780 790 800 310 320 330 340 350 360 pF1KB4 HCGRGFSCKPYLIRHQRTHTREKSFMCTVCGRGFREKSELIKHQRIHTGDKPYVCRD .:::::: : .:.::::::: :: ..: ::::::.::.:..::: :::.::::::. NP_001 ECGRGFSNKSHLLRHQRTHTGEKPYVCRECGRGFRNKSHLLRHQRTHTGEKPYVCRECGR 810 820 830 840 850 860 NP_001 GFSDRSSLCYHQRTHTGEKPYVCREDE 870 880 890 >-- initn: 5786 init1: 626 opt: 647 Z-score: 389.5 bits: 82.0 E(85289): 5.9e-15 Smith-Waterman score: 864; 45.7% identity (67.2% similar) in 293 aa overlap (79-364:385-668) 50 60 70 80 90 100 pF1KB4 WKRLSLEQRNLYKEVMLENLRNLVSLAESKPEVHTCPSCPLAFGSQQFLSQDELHNHP-- ::.: :::: :::.::.:::: .:: NP_001 VWYGDEYGQELGIKWGSKWKKELMAGREPKPEIHPCPSCCLAFSSQKFLSQHVERNHSSQ 360 370 380 390 400 410 110 120 130 140 150 160 pF1KB4 -IPGFHAGNQLHPGNPCPEDQPQSQHPSDKNHRGAEAEDQRVEGGVRPLFWSTNERGALV .:: : . :.: :::: :: : :. : . :. ... :... . : :.: NP_001 NFPGPSARKLLQPENPCPGDQNQEQQYPDPHSRNDKTKGQEIKERSKLL----NKRTWQR 420 430 440 450 460 470 170 180 190 200 210 220 pF1KB4 GFSSLFQRPPISSWG----GNRILEIQLSPAQNASSEEVDRISKRAETPGFGAVTFGECA .: :. :: .. : :.::.: . .:... .. .. . .. : .:::. NP_001 EISRAFSSPPKGQMGSCRVGKRIMEEESRTGQKVNPGNTGKLFVGVGISRIAKVKYGECG 480 490 500 510 520 530 230 240 250 260 270 280 pF1KB4 LAFNQKSNLFRQKAVTAEKSSDKRQSQVCRECGRGFSRKSQLIIHQRTHTGEKPYVCGEC .:. ::.. .: ... .. :::::::::: ::.:.:::: ::::::::: :: NP_001 QGFSVKSDV-----ITHQRTHTGEKLYVCRECGRGFSWKSHLLIHQRIHTGEKPYVCREC 540 550 560 570 580 290 300 310 320 330 340 pF1KB4 GRGFIVESVLRNHLSTHSGEKPYVCSHCGRGFSCKPYLIRHQRTHTREKSFMCTVCGRGF :::: .::: .: ::.::::::: .:::::: . :. ::: :: :: ..: ::::: NP_001 GRGFSWQSVLLTHQRTHTGEKPYVCRECGRGFSRQSVLLTHQRRHTGEKPYVCRECGRGF 590 600 610 620 630 640 350 360 pF1KB4 REKSELIKHQRIHTGDKPYVCRD ..: :. ::: :::.::::::. NP_001 SRQSVLLTHQRRHTGEKPYVCRECGRGFSWQSVLLSHQRTHTGEKPYVCRECGRGFSWQS 650 660 670 680 690 700 >>NP_001269937 (OMIM: 604075) zinc finger protein 133 is (559 aa) initn: 2170 init1: 584 opt: 612 Z-score: 371.6 bits: 78.0 E(85289): 5.8e-14 Smith-Waterman score: 842; 46.2% identity (69.9% similar) in 292 aa overlap (99-364:2-291) 70 80 90 100 110 120 pF1KB4 RNLVSLAESKPEVHTCPSCPLAFGSQQFLSQDELHNHPIPGFH---AGNQLHPGNPCPED : : ::: : : ....::.: : : NP_001 MQHVLCNHPPWIFTCLCAEGNIQPGDPGPGD 10 20 30 130 140 150 160 170 180 pF1KB4 QPQSQHPSDKNHRGAEAEDQRVEGGVRPLFWSTNERGALVGFSSLFQRPPISSWGGNRIL : ..:. :. . .:: . ::.. ::: :..: .: .:: :: :.:: .: : . NP_001 QEKQQQASEGRPWSDQAEGPEGEGAM-PLFGRTKKR-TLGAFSRPPQRQPVSSRNGLRGV 40 50 60 70 80 190 200 210 220 230 pF1KB4 EIQLSPAQNASSEEVDRISKRAETPGFGAVTFGECALAFNQKSNLFR------------- :.. ::::... ::.:.. :: :. :::.:. :::.:.:.. .::. NP_001 ELEASPAQTGNPEETDKLLKRIEVLGFGTVNCGECGLSFSKMTNLLSHQRIHSGEKPYVC 90 100 110 120 130 140 240 250 260 270 280 pF1KB4 ---QKAVTAEKSSDKRQSQ-------VCRECGRGFSRKSQLIIHQRTHTGEKPYVCGECG .:. . .:: ..:. :::::::::.::: ::::.:::.:::::.:.::: NP_001 GVCEKGFSLKKSLARHQKAHSGEKPIVCRECGRGFNRKSTLIIHERTHSGEKPYMCSECG 150 160 170 180 190 200 290 300 310 320 330 340 pF1KB4 RGFIVESVLRNHLSTHSGEKPYVCSHCGRGFSCKPYLIRHQRTHTREKSFMCTVCGRGFR ::: .: : : :::::::::: .::.::: : ..:::::: .::...:. :: :: NP_001 RGFSQKSNLIIHQRTHSGEKPYVCRECGKGFSQKSAVVRHQRTHLEEKTIVCSDCGLGFS 210 220 230 240 250 260 350 360 pF1KB4 EKSELIKHQRIHTGDKPYVCRD ..:.::.::: :.:.:::.:.. NP_001 DRSNLISHQRTHSGEKPYACKECGRCFRQRTTLVNHQRTHSKEKPYVCGVCGHSFSQNST 270 280 290 300 310 320 >-- initn: 1571 init1: 558 opt: 596 Z-score: 362.6 bits: 76.3 E(85289): 1.8e-13 Smith-Waterman score: 596; 52.4% identity (72.0% similar) in 168 aa overlap (197-364:325-487) 170 180 190 200 210 220 pF1KB4 FSSLFQRPPISSWGGNRILEIQLSPAQNASSEEVDRISKRAETPGFGAVTFGECALAFNQ :.. ::.: : . : :. .:. NP_001 CFRQRTTLVNHQRTHSKEKPYVCGVCGHSFSQNSTLISHRRTHTGEKPYVCGVCGRGFSL 300 310 320 330 340 350 230 240 250 260 270 280 pF1KB4 KSNLFRQKAVTAEKSSDKRQSQVCRECGRGFSRKSQLIIHQRTHTGEKPYVCGECGRGFI ::.: :.. . .:..: ::..::::::..:.:: :::::.::::.::::::::: NP_001 KSHLNRHQNI---HSGEK--PIVCKDCGRGFSQQSNLIRHQRTHSGEKPMVCGECGRGFS 360 370 380 390 400 290 300 310 320 330 340 pF1KB4 VESVLRNHLSTHSGEKPYVCSHCGRGFSCKPYLIRHQRTHTREKSFMCTVCGRGFREKSE .: : : :::::.:::: .:::::: . ::::.: :.::: .:: :: :: .:: NP_001 QKSNLVAHQRTHSGERPYVCRECGRGFSHQAGLIRHKRKHSREKPYMCRQCGLGFGNKSA 410 420 430 440 450 460 350 360 pF1KB4 LIKHQRIHTGDKPYVCRD :: :.: :. .:: :::. NP_001 LITHKRAHSEEKPCVCRECGQGFLQKSHLTLHQMTHTGEKPYVCKTCGRGFSLKSHLSRH 470 480 490 500 510 520 >>XP_016883547 (OMIM: 604075) PREDICTED: zinc finger pro (590 aa) initn: 2170 init1: 584 opt: 612 Z-score: 371.4 bits: 78.0 E(85289): 6e-14 Smith-Waterman score: 910; 45.3% identity (69.8% similar) in 318 aa overlap (73-364:7-322) 50 60 70 80 90 100 pF1KB4 LFTEAEWKRLSLEQRNLYKEVMLENLRNLVSLAESKPEVHTCPSCPLAFGSQQFLSQDEL .. . .::.. : :: .:.::.: : : XP_016 MCNGRKTVLDPEPELYLDPFCPPGFSSQKFPMQHVL 10 20 30 110 120 130 140 150 pF1KB4 HNHPIPGFH---AGNQLHPGNPCPEDQPQSQHPSDKNHRGAEAEDQRVEGGVRPLFWSTN ::: : : ....::.: : :: ..:. :. . .:: . ::.. ::: :. XP_016 CNHPPWIFTCLCAEGNIQPGDPGPGDQEKQQQASEGRPWSDQAEGPEGEGAM-PLFGRTK 40 50 60 70 80 90 160 170 180 190 200 210 pF1KB4 ERGALVGFSSLFQRPPISSWGGNRILEIQLSPAQNASSEEVDRISKRAETPGFGAVTFGE .: .: .:: :: :.:: .: : .:.. ::::... ::.:.. :: :. :::.:. :: XP_016 KR-TLGAFSRPPQRQPVSSRNGLRGVELEASPAQSGNPEETDKLLKRIEVLGFGTVNCGE 100 110 120 130 140 150 220 230 240 250 pF1KB4 CALAFNQKSNLFR----------------QKAVTAEKSSDKRQSQ-------VCRECGRG :.:.:.. .::. .:. . .:: ..:. :::::::: XP_016 CGLSFSKMTNLLSHQRIHSGEKPYVCGVCEKGFSLKKSLARHQKAHSGEKPIVCRECGRG 160 170 180 190 200 210 260 270 280 290 300 310 pF1KB4 FSRKSQLIIHQRTHTGEKPYVCGECGRGFIVESVLRNHLSTHSGEKPYVCSHCGRGFSCK :.::: ::::.:::.:::::.:.:::::: .: : : :::::::::: .::.::: : XP_016 FNRKSTLIIHERTHSGEKPYMCSECGRGFSQKSNLIIHQRTHSGEKPYVCRECGKGFSQK 220 230 240 250 260 270 320 330 340 350 360 pF1KB4 PYLIRHQRTHTREKSFMCTVCGRGFREKSELIKHQRIHTGDKPYVCRD ..:::::: .::...:. :: :: ..:.::.::: :.:.:::.:.. XP_016 SAVVRHQRTHLEEKTIVCSDCGLGFSDRSNLISHQRTHSGEKPYACKECGRCFRQRTTLV 280 290 300 310 320 330 XP_016 NHQRTHSKEKPYVCGVCGHSFSQNSTLISHRRTHTGEKPYVCGVCGRGFSLKSHLNRHQN 340 350 360 370 380 390 >-- initn: 1571 init1: 558 opt: 596 Z-score: 362.4 bits: 76.4 E(85289): 1.9e-13 Smith-Waterman score: 596; 52.4% identity (72.0% similar) in 168 aa overlap (197-364:356-518) 170 180 190 200 210 220 pF1KB4 FSSLFQRPPISSWGGNRILEIQLSPAQNASSEEVDRISKRAETPGFGAVTFGECALAFNQ :.. ::.: : . : :. .:. XP_016 CFRQRTTLVNHQRTHSKEKPYVCGVCGHSFSQNSTLISHRRTHTGEKPYVCGVCGRGFSL 330 340 350 360 370 380 230 240 250 260 270 280 pF1KB4 KSNLFRQKAVTAEKSSDKRQSQVCRECGRGFSRKSQLIIHQRTHTGEKPYVCGECGRGFI ::.: :.. . .:..: ::..::::::..:.:: :::::.::::.::::::::: XP_016 KSHLNRHQNI---HSGEK--PIVCKDCGRGFSQQSNLIRHQRTHSGEKPMVCGECGRGFS 390 400 410 420 430 440 290 300 310 320 330 340 pF1KB4 VESVLRNHLSTHSGEKPYVCSHCGRGFSCKPYLIRHQRTHTREKSFMCTVCGRGFREKSE .: : : :::::.:::: .:::::: . ::::.: :.::: .:: :: :: .:: XP_016 QKSNLVAHQRTHSGERPYVCRECGRGFSHQAGLIRHKRKHSREKPYMCRQCGLGFGNKSA 450 460 470 480 490 500 350 360 pF1KB4 LIKHQRIHTGDKPYVCRD :: :.: :. .:: :::. XP_016 LITHKRAHSEEKPCVCRECGQGFLQKSHLTLHQMTHTGEKPYVCKTCGRGFSLKSHLSRH 510 520 530 540 550 560 364 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 02:56:53 2016 done: Fri Nov 4 02:56:55 2016 Total Scan time: 8.920 Total Display time: 0.040 Function used was FASTA [36.3.4 Apr, 2011]