FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB4371, 158 aa 1>>>pF1KB4371 158 - 158 aa - 158 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.0110+/-0.000265; mu= 14.2662+/- 0.017 mean_var=69.7829+/-14.112, 0's: 0 Z-trim(120.3): 10 B-trim: 1547 in 1/51 Lambda= 0.153532 statistics sampled from 35467 (35477) to 35467 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.788), E-opt: 0.2 (0.416), width: 16 Scan time: 5.790 The best scores are: opt bits E(85289) XP_005250509 (OMIM: 604150) PREDICTED: DNA-directe ( 159) 1042 238.7 2.9e-63 XP_016867842 (OMIM: 604150) PREDICTED: DNA-directe ( 116) 683 159.1 2e-39 NP_116581 (OMIM: 609881) DNA-directed RNA polymera ( 115) 671 156.4 1.2e-38 NP_006225 (OMIM: 604150) DNA-directed RNA polymera ( 117) 671 156.5 1.3e-38 NP_057056 (OMIM: 613715,613717) DNA-directed RNA p ( 133) 182 48.2 5.6e-06 XP_005266469 (OMIM: 613715,613717) PREDICTED: DNA- ( 133) 182 48.2 5.6e-06 >>XP_005250509 (OMIM: 604150) PREDICTED: DNA-directed RN (159 aa) initn: 946 init1: 946 opt: 1042 Z-score: 1256.7 bits: 238.7 E(85289): 2.9e-63 Smith-Waterman score: 1042; 98.1% identity (98.1% similar) in 159 aa overlap (1-158:1-159) 10 20 30 40 50 pF1KB4 MNAPPAFESFLLFEGEK-ITINKDTKVPNACLFTINKEDHTLGNIIKSQLLKDPQVLFAG ::::::::::::::::: :::::::::::::::::::::::::::::::::::::::::: XP_005 MNAPPAFESFLLFEGEKKITINKDTKVPNACLFTINKEDHTLGNIIKSQLLKDPQVLFAG 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB4 YKVPHPLEHKIIIRVQTTPDYSPQEAFTNAITDLIRELSLLEERFRVRAGPGGADGVGWT ::::::::::::::::::::::::::::::::::: :::::::::::::::::::::::: XP_005 YKVPHPLEHKIIIRVQTTPDYSPQEAFTNAITDLISELSLLEERFRVRAGPGGADGVGWT 70 80 90 100 110 120 120 130 140 150 pF1KB4 LARVPRPGTALACFFGGPQGEAAVMEEQGLPPQAPGHVD :::::::::::::::::: :::::::::::::::::::: XP_005 LARVPRPGTALACFFGGPGGEAAVMEEQGLPPQAPGHVD 130 140 150 >>XP_016867842 (OMIM: 604150) PREDICTED: DNA-directed RN (116 aa) initn: 683 init1: 683 opt: 683 Z-score: 828.9 bits: 159.1 E(85289): 2e-39 Smith-Waterman score: 683; 99.1% identity (99.1% similar) in 106 aa overlap (1-106:1-106) 10 20 30 40 50 60 pF1KB4 MNAPPAFESFLLFEGEKITINKDTKVPNACLFTINKEDHTLGNIIKSQLLKDPQVLFAGY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MNAPPAFESFLLFEGEKITINKDTKVPNACLFTINKEDHTLGNIIKSQLLKDPQVLFAGY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 KVPHPLEHKIIIRVQTTPDYSPQEAFTNAITDLIRELSLLEERFRVRAGPGGADGVGWTL :::::::::::::::::::::::::::::::::: ::::::::::: XP_016 KVPHPLEHKIIIRVQTTPDYSPQEAFTNAITDLISELSLLEERFRVAIKDKQEGIE 70 80 90 100 110 130 140 150 pF1KB4 ARVPRPGTALACFFGGPQGEAAVMEEQGLPPQAPGHVD >>NP_116581 (OMIM: 609881) DNA-directed RNA polymerase I (115 aa) initn: 671 init1: 671 opt: 671 Z-score: 814.5 bits: 156.4 E(85289): 1.2e-38 Smith-Waterman score: 671; 98.1% identity (99.0% similar) in 105 aa overlap (1-105:1-105) 10 20 30 40 50 60 pF1KB4 MNAPPAFESFLLFEGEKITINKDTKVPNACLFTINKEDHTLGNIIKSQLLKDPQVLFAGY :::::::::::::::::::::::::::.:::::::::::::::::::::::::::::::: NP_116 MNAPPAFESFLLFEGEKITINKDTKVPKACLFTINKEDHTLGNIIKSQLLKDPQVLFAGY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 KVPHPLEHKIIIRVQTTPDYSPQEAFTNAITDLIRELSLLEERFRVRAGPGGADGVGWTL :::::::::::::::::::::::::::::::::: :::::::::: NP_116 KVPHPLEHKIIIRVQTTPDYSPQEAFTNAITDLISELSLLEERFRTCLLPLRLLP 70 80 90 100 110 130 140 150 pF1KB4 ARVPRPGTALACFFGGPQGEAAVMEEQGLPPQAPGHVD >>NP_006225 (OMIM: 604150) DNA-directed RNA polymerase I (117 aa) initn: 575 init1: 575 opt: 671 Z-score: 814.4 bits: 156.5 E(85289): 1.3e-38 Smith-Waterman score: 671; 98.1% identity (98.1% similar) in 107 aa overlap (1-106:1-107) 10 20 30 40 50 pF1KB4 MNAPPAFESFLLFEGEK-ITINKDTKVPNACLFTINKEDHTLGNIIKSQLLKDPQVLFAG ::::::::::::::::: :::::::::::::::::::::::::::::::::::::::::: NP_006 MNAPPAFESFLLFEGEKKITINKDTKVPNACLFTINKEDHTLGNIIKSQLLKDPQVLFAG 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB4 YKVPHPLEHKIIIRVQTTPDYSPQEAFTNAITDLIRELSLLEERFRVRAGPGGADGVGWT ::::::::::::::::::::::::::::::::::: ::::::::::: NP_006 YKVPHPLEHKIIIRVQTTPDYSPQEAFTNAITDLISELSLLEERFRVAIKDKQEGIE 70 80 90 100 110 120 130 140 150 pF1KB4 LARVPRPGTALACFFGGPQGEAAVMEEQGLPPQAPGHVD >>NP_057056 (OMIM: 613715,613717) DNA-directed RNA polym (133 aa) initn: 182 init1: 164 opt: 182 Z-score: 228.3 bits: 48.2 E(85289): 5.6e-06 Smith-Waterman score: 182; 32.6% identity (65.3% similar) in 95 aa overlap (14-104:20-114) 10 20 30 40 50 pF1KB4 MNAPPAFESFLLFEGEKITINKDTKVPNA---CL-FTINKEDHTLGNIIKSQLL :::. : . ... .. :. :....::::::: .. ... NP_057 MEEDQELERKISGLKTSMAEGERKTALEMVQAAGTDRHCVTFVLHEEDHTLGNSLRYMIM 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB4 KDPQVLFAGYKVPHPLEHKIIIRVQTTPDYSPQEAFTNAITDLIRELSLLEERFRVRAGP :.:.: : :: . :: : :: .:.:: : : ....:. . . ..: NP_057 KNPEVEFCGYTTTHPSESKINLRIQTRGTLPAVEPFQRGLNELMNVCQHVLDKFEASIKD 70 80 90 100 110 120 120 130 140 150 pF1KB4 GGADGVGWTLARVPRPGTALACFFGGPQGEAAVMEEQGLPPQAPGHVD NP_057 YKDQKASRNESTF 130 >>XP_005266469 (OMIM: 613715,613717) PREDICTED: DNA-dire (133 aa) initn: 182 init1: 164 opt: 182 Z-score: 228.3 bits: 48.2 E(85289): 5.6e-06 Smith-Waterman score: 182; 32.6% identity (65.3% similar) in 95 aa overlap (14-104:20-114) 10 20 30 40 50 pF1KB4 MNAPPAFESFLLFEGEKITINKDTKVPNA---CL-FTINKEDHTLGNIIKSQLL :::. : . ... .. :. :....::::::: .. ... XP_005 MEEDQELERKISGLKTSMAEGERKTALEMVQAAGTDRHCVTFVLHEEDHTLGNSLRYMIM 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB4 KDPQVLFAGYKVPHPLEHKIIIRVQTTPDYSPQEAFTNAITDLIRELSLLEERFRVRAGP :.:.: : :: . :: : :: .:.:: : : ....:. . . ..: XP_005 KNPEVEFCGYTTTHPSESKINLRIQTRGTLPAVEPFQRGLNELMNVCQHVLDKFEASIKD 70 80 90 100 110 120 120 130 140 150 pF1KB4 GGADGVGWTLARVPRPGTALACFFGGPQGEAAVMEEQGLPPQAPGHVD XP_005 YKDQKASRNESTF 130 158 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 14:51:52 2016 done: Thu Nov 3 14:51:53 2016 Total Scan time: 5.790 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]