FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB4374, 414 aa 1>>>pF1KB4374 414 - 414 aa - 414 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.8929+/-0.000818; mu= 14.3893+/- 0.050 mean_var=75.7558+/-15.374, 0's: 0 Z-trim(108.8): 72 B-trim: 199 in 1/48 Lambda= 0.147356 statistics sampled from 10369 (10447) to 10369 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.697), E-opt: 0.2 (0.321), width: 16 Scan time: 2.980 The best scores are: opt bits E(32554) CCDS55866.1 ANKS1B gene_id:56899|Hs108|chr12 ( 414) 2812 607.1 1e-173 CCDS55867.1 ANKS1B gene_id:56899|Hs108|chr12 ( 426) 2657 574.1 8.6e-164 CCDS55871.1 ANKS1B gene_id:56899|Hs108|chr12 ( 394) 2412 522.0 3.8e-148 CCDS55864.1 ANKS1B gene_id:56899|Hs108|chr12 ( 254) 1520 332.3 3.2e-91 CCDS55872.1 ANKS1B gene_id:56899|Hs108|chr12 (1248) 1521 332.8 1.1e-90 CCDS55869.1 ANKS1B gene_id:56899|Hs108|chr12 ( 460) 1361 298.6 8e-81 CCDS55868.1 ANKS1B gene_id:56899|Hs108|chr12 ( 450) 1352 296.7 3e-80 CCDS55870.1 ANKS1B gene_id:56899|Hs108|chr12 ( 510) 1352 296.7 3.3e-80 CCDS55865.1 ANKS1B gene_id:56899|Hs108|chr12 ( 357) 1347 295.6 5.1e-80 CCDS4798.1 ANKS1A gene_id:23294|Hs108|chr6 (1134) 655 148.7 2.7e-35 CCDS58742.1 GULP1 gene_id:51454|Hs108|chr2 ( 291) 306 74.2 1.8e-13 CCDS2295.1 GULP1 gene_id:51454|Hs108|chr2 ( 304) 306 74.2 1.8e-13 >>CCDS55866.1 ANKS1B gene_id:56899|Hs108|chr12 (414 aa) initn: 2812 init1: 2812 opt: 2812 Z-score: 3232.3 bits: 607.1 E(32554): 1e-173 Smith-Waterman score: 2812; 100.0% identity (100.0% similar) in 414 aa overlap (1-414:1-414) 10 20 30 40 50 60 pF1KB4 MMWQCHLSAQDYRYYPVDGYSLLKRFPLHPLTGPRCPVQTVGQWLESIGLPQYENHLMAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 MMWQCHLSAQDYRYYPVDGYSLLKRFPLHPLTGPRCPVQTVGQWLESIGLPQYENHLMAN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 GFDNVQFMGSNVMEDQDLLEIGILNSGHRQRILQAIQLLPKMRPIGHDGYHPTSVAEWLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 GFDNVQFMGSNVMEDQDLLEIGILNSGHRQRILQAIQLLPKMRPIGHDGYHPTSVAEWLD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 SIELGDYTKAFLINGYTSMDLLKKIWEVELINVLKINLIGHRKRILASLGDRLHDDPPQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 SIELGDYTKAFLINGYTSMDLLKKIWEVELINVLKINLIGHRKRILASLGDRLHDDPPQK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 PPRSITLRTGDWGEPSITLRPPNEATASTPVQYWQHHPEKLIFQSCDYKAFYLGSMLIKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 PPRSITLRTGDWGEPSITLRPPNEATASTPVQYWQHHPEKLIFQSCDYKAFYLGSMLIKE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 LRGTESTQDACAKMRANCQKSTEQMKKVPTIILSVSYKGVKFIDATNKNIIAEHEIRNIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 LRGTESTQDACAKMRANCQKSTEQMKKVPTIILSVSYKGVKFIDATNKNIIAEHEIRNIS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 CAAQDPEDLSTFAYITKDLKSNHHYCHVFTAFDVNLAYEIILTLGQAFEVAYQLALQARK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 CAAQDPEDLSTFAYITKDLKSNHHYCHVFTAFDVNLAYEIILTLGQAFEVAYQLALQARK 310 320 330 340 350 360 370 380 390 400 410 pF1KB4 GGHSSTLPESFENKPSKPIPKPRVSIRKSVDLLHASHTGQEPSERHTEEALRKF :::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 GGHSSTLPESFENKPSKPIPKPRVSIRKSVDLLHASHTGQEPSERHTEEALRKF 370 380 390 400 410 >>CCDS55867.1 ANKS1B gene_id:56899|Hs108|chr12 (426 aa) initn: 2736 init1: 2654 opt: 2657 Z-score: 3054.0 bits: 574.1 E(32554): 8.6e-164 Smith-Waterman score: 2657; 96.8% identity (98.0% similar) in 407 aa overlap (1-407:1-399) 10 20 30 40 50 60 pF1KB4 MMWQCHLSAQDYRYYPVDGYSLLKRFPLHPLTGPRCPVQTVGQWLESIGLPQYENHLMAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 MMWQCHLSAQDYRYYPVDGYSLLKRFPLHPLTGPRCPVQTVGQWLESIGLPQYENHLMAN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 GFDNVQFMGSNVMEDQDLLEIGILNSGHRQRILQAIQLLPKMRPIGHDGYHPTSVAEWLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 GFDNVQFMGSNVMEDQDLLEIGILNSGHRQRILQAIQLLPKMRPIGHDGYHPTSVAEWLD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 SIELGDYTKAFLINGYTSMDLLKKIWEVELINVLKINLIGHRKRILASLGDRLHDDPPQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 SIELGDYTKAFLINGYTSMDLLKKIWEVELINVLKINLIGHRKRILASLGDRLHDDPPQK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 PPRSITLRTGDWGEPSITLRPPNEATASTPVQYWQHHPEKLIFQSCDYKAFYLGSMLIKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 PPRSITLRTGDWGEPSITLRPPNEATASTPVQYWQHHPEKLIFQSCDYKAFYLGSMLIKE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 LRGTESTQDACAKMRANCQKSTEQMKKVPTIILSVSYKGVKFIDATNKNIIAEHEIRNIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 LRGTESTQDACAKMRANCQKSTEQMKKVPTIILSVSYKGVKFIDATNKNIIAEHEIRNIS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 CAAQDPEDLSTFAYITKDLKSNHHYCHVFTAFDVNLAYEIILTLGQAFEVAYQLALQARK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 CAAQDPEDLSTFAYITKDLKSNHHYCHVFTAFDVNLAYEIILTLGQAFEVAYQLALQARK 310 320 330 340 350 360 370 380 390 400 410 pF1KB4 GGHSSTLPESFENKPSKPIPKPRVSIRKSVDLLHASHTGQEPSERHTEEALRKF ::::::::::::::::::::::::::::::.. .:::..: CCDS55 GGHSSTLPESFENKPSKPIPKPRVSIRKSVQI--------DPSEQKTLANLPWIVEPGQE 370 380 390 400 410 CCDS55 AKRGINTKYETTIF 420 >>CCDS55871.1 ANKS1B gene_id:56899|Hs108|chr12 (394 aa) initn: 2412 init1: 2412 opt: 2412 Z-score: 2773.1 bits: 522.0 E(32554): 3.8e-148 Smith-Waterman score: 2412; 100.0% identity (100.0% similar) in 358 aa overlap (33-390:2-359) 10 20 30 40 50 60 pF1KB4 WQCHLSAQDYRYYPVDGYSLLKRFPLHPLTGPRCPVQTVGQWLESIGLPQYENHLMANGF :::::::::::::::::::::::::::::: CCDS55 MGPRCPVQTVGQWLESIGLPQYENHLMANGF 10 20 30 70 80 90 100 110 120 pF1KB4 DNVQFMGSNVMEDQDLLEIGILNSGHRQRILQAIQLLPKMRPIGHDGYHPTSVAEWLDSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 DNVQFMGSNVMEDQDLLEIGILNSGHRQRILQAIQLLPKMRPIGHDGYHPTSVAEWLDSI 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB4 ELGDYTKAFLINGYTSMDLLKKIWEVELINVLKINLIGHRKRILASLGDRLHDDPPQKPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 ELGDYTKAFLINGYTSMDLLKKIWEVELINVLKINLIGHRKRILASLGDRLHDDPPQKPP 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB4 RSITLRTGDWGEPSITLRPPNEATASTPVQYWQHHPEKLIFQSCDYKAFYLGSMLIKELR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 RSITLRTGDWGEPSITLRPPNEATASTPVQYWQHHPEKLIFQSCDYKAFYLGSMLIKELR 160 170 180 190 200 210 250 260 270 280 290 300 pF1KB4 GTESTQDACAKMRANCQKSTEQMKKVPTIILSVSYKGVKFIDATNKNIIAEHEIRNISCA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 GTESTQDACAKMRANCQKSTEQMKKVPTIILSVSYKGVKFIDATNKNIIAEHEIRNISCA 220 230 240 250 260 270 310 320 330 340 350 360 pF1KB4 AQDPEDLSTFAYITKDLKSNHHYCHVFTAFDVNLAYEIILTLGQAFEVAYQLALQARKGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 AQDPEDLSTFAYITKDLKSNHHYCHVFTAFDVNLAYEIILTLGQAFEVAYQLALQARKGG 280 290 300 310 320 330 370 380 390 400 410 pF1KB4 HSSTLPESFENKPSKPIPKPRVSIRKSVDLLHASHTGQEPSERHTEEALRKF :::::::::::::::::::::::::::: CCDS55 HSSTLPESFENKPSKPIPKPRVSIRKSVIDPSEQKTLANLPWIVEPGQEAKRGINTKYET 340 350 360 370 380 390 >>CCDS55864.1 ANKS1B gene_id:56899|Hs108|chr12 (254 aa) initn: 1520 init1: 1520 opt: 1520 Z-score: 1751.2 bits: 332.3 E(32554): 3.2e-91 Smith-Waterman score: 1520; 95.4% identity (97.1% similar) in 240 aa overlap (175-414:15-254) 150 160 170 180 190 200 pF1KB4 IWEVELINVLKINLIGHRKRILASLGDRLHDDPPQKPPRSITLRTGDWGEPSITLRPPNE :: :.. . .:::::::::::::::: CCDS55 MQGDARRRRNENYFDDIPRSKLERQMAQTGDWGEPSITLRPPNE 10 20 30 40 210 220 230 240 250 260 pF1KB4 ATASTPVQYWQHHPEKLIFQSCDYKAFYLGSMLIKELRGTESTQDACAKMRANCQKSTEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 ATASTPVQYWQHHPEKLIFQSCDYKAFYLGSMLIKELRGTESTQDACAKMRANCQKSTEQ 50 60 70 80 90 100 270 280 290 300 310 320 pF1KB4 MKKVPTIILSVSYKGVKFIDATNKNIIAEHEIRNISCAAQDPEDLSTFAYITKDLKSNHH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 MKKVPTIILSVSYKGVKFIDATNKNIIAEHEIRNISCAAQDPEDLSTFAYITKDLKSNHH 110 120 130 140 150 160 330 340 350 360 370 380 pF1KB4 YCHVFTAFDVNLAYEIILTLGQAFEVAYQLALQARKGGHSSTLPESFENKPSKPIPKPRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 YCHVFTAFDVNLAYEIILTLGQAFEVAYQLALQARKGGHSSTLPESFENKPSKPIPKPRV 170 180 190 200 210 220 390 400 410 pF1KB4 SIRKSVDLLHASHTGQEPSERHTEEALRKF :::::::::::::::::::::::::::::: CCDS55 SIRKSVDLLHASHTGQEPSERHTEEALRKF 230 240 250 >>CCDS55872.1 ANKS1B gene_id:56899|Hs108|chr12 (1248 aa) initn: 1602 init1: 1520 opt: 1521 Z-score: 1741.6 bits: 332.8 E(32554): 1.1e-90 Smith-Waterman score: 2436; 86.2% identity (86.2% similar) in 443 aa overlap (32-414:806-1248) 10 20 30 40 50 60 pF1KB4 MWQCHLSAQDYRYYPVDGYSLLKRFPLHPLTGPRCPVQTVGQWLESIGLPQYENHLMANG : :::::::::::::::::::::::::::: CCDS55 FTSEWEEIDKIMSSIDVGINNELKEMNGETTRPRCPVQTVGQWLESIGLPQYENHLMANG 780 790 800 810 820 830 70 80 90 100 110 120 pF1KB4 FDNVQFMGSNVMEDQDLLEIGILNSGHRQRILQAIQLLPKMRPIGHDGYHPTSVAEWLDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 FDNVQFMGSNVMEDQDLLEIGILNSGHRQRILQAIQLLPKMRPIGHDGYHPTSVAEWLDS 840 850 860 870 880 890 130 140 150 160 170 180 pF1KB4 IELGDYTKAFLINGYTSMDLLKKIWEVELINVLKINLIGHRKRILASLGDRLHDDPPQKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 IELGDYTKAFLINGYTSMDLLKKIWEVELINVLKINLIGHRKRILASLGDRLHDDPPQKP 900 910 920 930 940 950 pF1KB4 PRSITLR----------------------------------------------------- ::::::: CCDS55 PRSITLREPSGNHTPPQLSPSLSQSTYTTGGSLDVPHIIMQGDARRRRNENYFDDIPRSK 960 970 980 990 1000 1010 190 200 210 220 230 240 pF1KB4 -------TGDWGEPSITLRPPNEATASTPVQYWQHHPEKLIFQSCDYKAFYLGSMLIKEL ::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 LERQMAQTGDWGEPSITLRPPNEATASTPVQYWQHHPEKLIFQSCDYKAFYLGSMLIKEL 1020 1030 1040 1050 1060 1070 250 260 270 280 290 300 pF1KB4 RGTESTQDACAKMRANCQKSTEQMKKVPTIILSVSYKGVKFIDATNKNIIAEHEIRNISC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 RGTESTQDACAKMRANCQKSTEQMKKVPTIILSVSYKGVKFIDATNKNIIAEHEIRNISC 1080 1090 1100 1110 1120 1130 310 320 330 340 350 360 pF1KB4 AAQDPEDLSTFAYITKDLKSNHHYCHVFTAFDVNLAYEIILTLGQAFEVAYQLALQARKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 AAQDPEDLSTFAYITKDLKSNHHYCHVFTAFDVNLAYEIILTLGQAFEVAYQLALQARKG 1140 1150 1160 1170 1180 1190 370 380 390 400 410 pF1KB4 GHSSTLPESFENKPSKPIPKPRVSIRKSVDLLHASHTGQEPSERHTEEALRKF ::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 GHSSTLPESFENKPSKPIPKPRVSIRKSVDLLHASHTGQEPSERHTEEALRKF 1200 1210 1220 1230 1240 >>CCDS55869.1 ANKS1B gene_id:56899|Hs108|chr12 (460 aa) initn: 1360 init1: 1360 opt: 1361 Z-score: 1564.5 bits: 298.6 E(32554): 8e-81 Smith-Waterman score: 2312; 85.8% identity (85.8% similar) in 422 aa overlap (29-390:29-450) 10 20 30 40 50 60 pF1KB4 MMWQCHLSAQDYRYYPVDGYSLLKRFPLHPLTGPRCPVQTVGQWLESIGLPQYENHLMAN :::::::::::::::::::::::::::::::: CCDS55 MMWQCHLSAQDYRYYPVDGYSLLKRFPLHPLTGPRCPVQTVGQWLESIGLPQYENHLMAN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 GFDNVQFMGSNVMEDQDLLEIGILNSGHRQRILQAIQLLPKMRPIGHDGYHPTSVAEWLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 GFDNVQFMGSNVMEDQDLLEIGILNSGHRQRILQAIQLLPKMRPIGHDGYHPTSVAEWLD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 SIELGDYTKAFLINGYTSMDLLKKIWEVELINVLKINLIGHRKRILASLGDRLHDDPPQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 SIELGDYTKAFLINGYTSMDLLKKIWEVELINVLKINLIGHRKRILASLGDRLHDDPPQK 130 140 150 160 170 180 pF1KB4 PPRSITLR---------------------------------------------------- :::::::: CCDS55 PPRSITLREPSGNHTPPQLSPSLSQSTYTTGGSLDVPHIIMQGDARRRRNENYFDDIPRS 190 200 210 220 230 240 190 200 210 220 230 240 pF1KB4 --------TGDWGEPSITLRPPNEATASTPVQYWQHHPEKLIFQSCDYKAFYLGSMLIKE :::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 KLERQMAQTGDWGEPSITLRPPNEATASTPVQYWQHHPEKLIFQSCDYKAFYLGSMLIKE 250 260 270 280 290 300 250 260 270 280 290 300 pF1KB4 LRGTESTQDACAKMRANCQKSTEQMKKVPTIILSVSYKGVKFIDATNKNIIAEHEIRNIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 LRGTESTQDACAKMRANCQKSTEQMKKVPTIILSVSYKGVKFIDATNKNIIAEHEIRNIS 310 320 330 340 350 360 310 320 330 340 350 360 pF1KB4 CAAQDPEDLSTFAYITKDLKSNHHYCHVFTAFDVNLAYEIILTLGQAFEVAYQLALQARK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 CAAQDPEDLSTFAYITKDLKSNHHYCHVFTAFDVNLAYEIILTLGQAFEVAYQLALQARK 370 380 390 400 410 420 370 380 390 400 410 pF1KB4 GGHSSTLPESFENKPSKPIPKPRVSIRKSVDLLHASHTGQEPSERHTEEALRKF :::::::::::::::::::::::::::::: CCDS55 GGHSSTLPESFENKPSKPIPKPRVSIRKSVPFCFKADRPI 430 440 450 460 >>CCDS55868.1 ANKS1B gene_id:56899|Hs108|chr12 (450 aa) initn: 2642 init1: 1349 opt: 1352 Z-score: 1554.3 bits: 296.7 E(32554): 3e-80 Smith-Waterman score: 2599; 91.4% identity (92.6% similar) in 431 aa overlap (1-407:1-423) 10 20 30 40 50 60 pF1KB4 MMWQCHLSAQDYRYYPVDGYSLLKRFPLHPLTGPRCPVQTVGQWLESIGLPQYENHLMAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 MMWQCHLSAQDYRYYPVDGYSLLKRFPLHPLTGPRCPVQTVGQWLESIGLPQYENHLMAN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 GFDNVQFMGSNVMEDQDLLEIGILNSGHRQRILQAIQLLPKMRPIGHDGYHPTSVAEWLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 GFDNVQFMGSNVMEDQDLLEIGILNSGHRQRILQAIQLLPKMRPIGHDGYHPTSVAEWLD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 SIELGDYTKAFLINGYTSMDLLKKIWEVELINVLKINLIGHRKRILASLGDRLHDDPPQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 SIELGDYTKAFLINGYTSMDLLKKIWEVELINVLKINLIGHRKRILASLGDRLHDDPPQK 130 140 150 160 170 180 190 200 210 pF1KB4 PPRSITLR------------------------TGDWGEPSITLRPPNEATASTPVQYWQH :::::::: :::::::::::::::::::::::::::: CCDS55 PPRSITLRSSVCEIWTNQNAGFPFSAIHQVHNTGDWGEPSITLRPPNEATASTPVQYWQH 190 200 210 220 230 240 220 230 240 250 260 270 pF1KB4 HPEKLIFQSCDYKAFYLGSMLIKELRGTESTQDACAKMRANCQKSTEQMKKVPTIILSVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 HPEKLIFQSCDYKAFYLGSMLIKELRGTESTQDACAKMRANCQKSTEQMKKVPTIILSVS 250 260 270 280 290 300 280 290 300 310 320 330 pF1KB4 YKGVKFIDATNKNIIAEHEIRNISCAAQDPEDLSTFAYITKDLKSNHHYCHVFTAFDVNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 YKGVKFIDATNKNIIAEHEIRNISCAAQDPEDLSTFAYITKDLKSNHHYCHVFTAFDVNL 310 320 330 340 350 360 340 350 360 370 380 390 pF1KB4 AYEIILTLGQAFEVAYQLALQARKGGHSSTLPESFENKPSKPIPKPRVSIRKSVDLLHAS ::::::::::::::::::::::::::::::::::::::::::::::::::::::.. CCDS55 AYEIILTLGQAFEVAYQLALQARKGGHSSTLPESFENKPSKPIPKPRVSIRKSVQI---- 370 380 390 400 410 400 410 pF1KB4 HTGQEPSERHTEEALRKF .:::..: CCDS55 ----DPSEQKTLANLPWIVEPGQEAKRGINTKYETTIF 420 430 440 450 >>CCDS55870.1 ANKS1B gene_id:56899|Hs108|chr12 (510 aa) initn: 2640 init1: 1349 opt: 1352 Z-score: 1553.5 bits: 296.7 E(32554): 3.3e-80 Smith-Waterman score: 2088; 77.9% identity (79.0% similar) in 439 aa overlap (53-407:53-483) 30 40 50 60 70 80 pF1KB4 LKRFPLHPLTGPRCPVQTVGQWLESIGLPQYENHLMANGFDNVQFMGSNVMEDQDLLEIG :::::::::::::::::::::::::::::: CCDS55 LKRFPLHPLTGPRCPVQTVGQWLESIGLPQYENHLMANGFDNVQFMGSNVMEDQDLLEIG 30 40 50 60 70 80 90 100 110 120 130 140 pF1KB4 ILNSGHRQRILQAIQLLPKMRPIGHDGYHPTSVAEWLDSIELGDYTKAFLINGYTSMDLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 ILNSGHRQRILQAIQLLPKMRPIGHDGYHPTSVAEWLDSIELGDYTKAFLINGYTSMDLL 90 100 110 120 130 140 150 160 170 180 pF1KB4 KKIWEVELINVLKINLIGHRKRILASLGDRLHDDPPQKPPRSITLR-------------- :::::::::::::::::::::::::::::::::::::::::::::: CCDS55 KKIWEVELINVLKINLIGHRKRILASLGDRLHDDPPQKPPRSITLREPSGNHTPPQLSPS 150 160 170 180 190 200 pF1KB4 ------------------------------------------------------------ CCDS55 LSQSTYTTGGSLDVPHIIMQGDARRRRNENYFDDIPRSKLERQMAQSSVCEIWTNQNAGF 210 220 230 240 250 260 190 200 210 220 230 pF1KB4 ----------TGDWGEPSITLRPPNEATASTPVQYWQHHPEKLIFQSCDYKAFYLGSMLI :::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 PFSAIHQVHNTGDWGEPSITLRPPNEATASTPVQYWQHHPEKLIFQSCDYKAFYLGSMLI 270 280 290 300 310 320 240 250 260 270 280 290 pF1KB4 KELRGTESTQDACAKMRANCQKSTEQMKKVPTIILSVSYKGVKFIDATNKNIIAEHEIRN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 KELRGTESTQDACAKMRANCQKSTEQMKKVPTIILSVSYKGVKFIDATNKNIIAEHEIRN 330 340 350 360 370 380 300 310 320 330 340 350 pF1KB4 ISCAAQDPEDLSTFAYITKDLKSNHHYCHVFTAFDVNLAYEIILTLGQAFEVAYQLALQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 ISCAAQDPEDLSTFAYITKDLKSNHHYCHVFTAFDVNLAYEIILTLGQAFEVAYQLALQA 390 400 410 420 430 440 360 370 380 390 400 410 pF1KB4 RKGGHSSTLPESFENKPSKPIPKPRVSIRKSVDLLHASHTGQEPSERHTEEALRKF ::::::::::::::::::::::::::::::::.. .:::..: CCDS55 RKGGHSSTLPESFENKPSKPIPKPRVSIRKSVQI--------DPSEQKTLANLPWIVEPG 450 460 470 480 490 CCDS55 QEAKRGINTKYETTIF 500 510 >-- initn: 391 init1: 391 opt: 391 Z-score: 449.3 bits: 92.4 E(32554): 1e-18 Smith-Waterman score: 391; 100.0% identity (100.0% similar) in 52 aa overlap (1-52:1-52) 10 20 30 40 50 60 pF1KB4 MMWQCHLSAQDYRYYPVDGYSLLKRFPLHPLTGPRCPVQTVGQWLESIGLPQYENHLMAN :::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 MMWQCHLSAQDYRYYPVDGYSLLKRFPLHPLTGPRCPVQTVGQWLESIGLPQYENHLMAN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 GFDNVQFMGSNVMEDQDLLEIGILNSGHRQRILQAIQLLPKMRPIGHDGYHPTSVAEWLD CCDS55 GFDNVQFMGSNVMEDQDLLEIGILNSGHRQRILQAIQLLPKMRPIGHDGYHPTSVAEWLD 70 80 90 100 110 120 >>CCDS55865.1 ANKS1B gene_id:56899|Hs108|chr12 (357 aa) initn: 1969 init1: 1347 opt: 1347 Z-score: 1550.1 bits: 295.6 E(32554): 5.1e-80 Smith-Waterman score: 1933; 90.1% identity (92.8% similar) in 333 aa overlap (58-390:1-322) 30 40 50 60 70 80 pF1KB4 LHPLTGPRCPVQTVGQWLESIGLPQYENHLMANGFDNVQFMGSNVMEDQDLLEIGILNSG :::::::::::::::::::::::::::::: CCDS55 MANGFDNVQFMGSNVMEDQDLLEIGILNSG 10 20 30 90 100 110 120 130 140 pF1KB4 HRQRILQAIQLLPKMRPIGHDGYHPTSVAEWLDSIELGDYTKAFLINGYTSMDLLKKIWE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 HRQRILQAIQLLPKMRPIGHDGYHPTSVAEWLDSIELGDYTKAFLINGYTSMDLLKKIWE 40 50 60 70 80 90 150 160 170 180 190 200 pF1KB4 VELINVLKINLIGHRKRILASLGDRLHDDPPQKPPRSITLRTGDWGEPSITLRPPNEATA ::::: .. : . :.. : . ... ::::::::::::::::::: CCDS55 VELINQSSVCEIWTNQN--AGF--------PFSAIHQVH-NTGDWGEPSITLRPPNEATA 100 110 120 130 210 220 230 240 250 260 pF1KB4 STPVQYWQHHPEKLIFQSCDYKAFYLGSMLIKELRGTESTQDACAKMRANCQKSTEQMKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 STPVQYWQHHPEKLIFQSCDYKAFYLGSMLIKELRGTESTQDACAKMRANCQKSTEQMKK 140 150 160 170 180 190 270 280 290 300 310 320 pF1KB4 VPTIILSVSYKGVKFIDATNKNIIAEHEIRNISCAAQDPEDLSTFAYITKDLKSNHHYCH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 VPTIILSVSYKGVKFIDATNKNIIAEHEIRNISCAAQDPEDLSTFAYITKDLKSNHHYCH 200 210 220 230 240 250 330 340 350 360 370 380 pF1KB4 VFTAFDVNLAYEIILTLGQAFEVAYQLALQARKGGHSSTLPESFENKPSKPIPKPRVSIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 VFTAFDVNLAYEIILTLGQAFEVAYQLALQARKGGHSSTLPESFENKPSKPIPKPRVSIR 260 270 280 290 300 310 390 400 410 pF1KB4 KSVDLLHASHTGQEPSERHTEEALRKF ::: CCDS55 KSVIDPSEQKTLANLPWIVEPGQEAKRGINTKYETTIF 320 330 340 350 >>CCDS4798.1 ANKS1A gene_id:23294|Hs108|chr6 (1134 aa) initn: 1679 init1: 639 opt: 655 Z-score: 747.3 bits: 148.7 E(32554): 2.7e-35 Smith-Waterman score: 1507; 58.2% identity (75.8% similar) in 414 aa overlap (31-389:691-1100) 10 20 30 40 50 60 pF1KB4 MMWQCHLSAQDYRYYPVDGYSLLKRFPLHPLTGPRCPVQTVGQWLESIGLPQYENHLMAN ..: : :.::.::::::: :::..:. : CCDS47 SPSFASEWDEIEKIMSSIGEGIDFSQERQKISGLRTLEQSVGEWLESIGLQQYESKLLLN 670 680 690 700 710 720 70 80 90 100 110 120 pF1KB4 GFDNVQFMGSNVMEDQDLLEIGILNSGHRQRILQAIQLLPKMRPIGHDGYHPTSVAEWLD :::.:.:.::::::.::: .::: . ::...::: . :::.. .:.:: : :: ::: CCDS47 GFDDVHFLGSNVMEEQDLRDIGISDPQHRRKLLQAARSLPKVKALGYDGNSPPSVPSWLD 730 740 750 760 770 780 130 140 150 160 170 180 pF1KB4 SIELGDYTKAFLINGYTSMDLLKKIWEVELINVLKINLIGHRKRILASLGDRLHDDPPQK :. : ::...:: .::.:.: .:..::.::.::::..:.::::::.:::.:: ...:::: CCDS47 SLGLQDYVHSFLSSGYSSIDTVKNLWELELVNVLKVQLLGHRKRIIASLADRPYEEPPQK 790 800 810 820 830 840 190 pF1KB4 PPRSITLRT----------------------------GDWGE-----------PS----- ::: :: :: :. :: CCDS47 PPRFSQLRCQDLLSQTSSPLSQNDSCTGRSADLLLPPGDTGRRRHDSLHDPAAPSRAERF 850 860 870 880 890 900 200 210 220 230 240 pF1KB4 ----------ITLRPPNEATASTPVQYWQHHPEKLIFQSCDYKAFYLGSMLIKELRGTES .:::::. :. .::: :::.::::::.:: :.: ::::::::.:::::: CCDS47 RIQEEHREAKLTLRPPSLAAPYAPVQSWQHQPEKLIFESCGYEANYLGSMLIKDLRGTES 910 920 930 940 950 960 250 260 270 280 290 300 pF1KB4 TQDACAKMRANCQKSTEQMKKVPTIILSVSYKGVKFIDATNKNIIAEHEIRNISCAAQDP ::::::::: ::::.:::.::::::..:::::::::.:::.:::::::::::::::: CCDS47 TQDACAKMR----KSTEHMKKIPTIILSITYKGVKFIDASNKNVIAEHEIRNISCAAQDP 970 980 990 1000 1010 310 320 330 340 350 360 pF1KB4 EDLSTFAYITKDLKSNHHYCHVFTAFDVNLAYEIILTLGQAFEVAYQLALQARKG-GHSS ::: :::::::::...:::::::.. ::::.:::::::::::::::::::::.:. . .. CCDS47 EDLCTFAYITKDLQTSHHYCHVFSTVDVNLTYEIILTLGQAFEVAYQLALQAQKSRATGA 1020 1030 1040 1050 1060 1070 370 380 390 400 410 pF1KB4 TLPESFENKPSKPIPKPRVSIRKSVDLLHASHTGQEPSERHTEEALRKF . : .:.: :::.:::::..::: CCDS47 SAAEMIETKSSKPVPKPRVGVRKSALEPPDMDQDAQSHASVSWVVDPKPDSKRSLSTN 1080 1090 1100 1110 1120 1130 414 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 05:49:03 2016 done: Sat Nov 5 05:49:03 2016 Total Scan time: 2.980 Total Display time: 0.060 Function used was FASTA [36.3.4 Apr, 2011]