FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB4380, 391 aa 1>>>pF1KB4380 391 - 391 aa - 391 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.4687+/-0.000352; mu= 13.8046+/- 0.023 mean_var=153.9263+/-32.703, 0's: 0 Z-trim(118.9): 747 B-trim: 1384 in 1/57 Lambda= 0.103376 statistics sampled from 31443 (32292) to 31443 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.708), E-opt: 0.2 (0.379), width: 16 Scan time: 9.000 The best scores are: opt bits E(85289) NP_001040 (OMIM: 182451) somatostatin receptor typ ( 391) 2580 396.4 6e-110 NP_001043 (OMIM: 182454) somatostatin receptor typ ( 388) 1463 229.8 8.5e-60 NP_001041 (OMIM: 182452) somatostatin receptor typ ( 369) 1143 182.1 1.9e-45 NP_001166031 (OMIM: 182455) somatostatin receptor ( 364) 1087 173.7 6.2e-43 NP_001044 (OMIM: 182455) somatostatin receptor typ ( 364) 1087 173.7 6.2e-43 XP_016884412 (OMIM: 182453) PREDICTED: somatostati ( 418) 1049 168.1 3.4e-41 NP_001042 (OMIM: 182453) somatostatin receptor typ ( 418) 1049 168.1 3.4e-41 XP_016884413 (OMIM: 182453) PREDICTED: somatostati ( 418) 1049 168.1 3.4e-41 XP_005261778 (OMIM: 182453) PREDICTED: somatostati ( 418) 1049 168.1 3.4e-41 XP_006724374 (OMIM: 182453) PREDICTED: somatostati ( 418) 1049 168.1 3.4e-41 NP_001265616 (OMIM: 182453) somatostatin receptor ( 418) 1049 168.1 3.4e-41 XP_011528651 (OMIM: 182453) PREDICTED: somatostati ( 418) 1049 168.1 3.4e-41 NP_000905 (OMIM: 600018) mu-type opioid receptor i ( 400) 923 149.3 1.5e-35 NP_001272453 (OMIM: 600018) mu-type opioid recepto ( 493) 923 149.4 1.7e-35 NP_001138751 (OMIM: 600018) mu-type opioid recepto ( 493) 923 149.4 1.7e-35 NP_001138757 (OMIM: 600018) mu-type opioid recepto ( 389) 917 148.4 2.8e-35 NP_001008504 (OMIM: 600018) mu-type opioid recepto ( 392) 917 148.4 2.8e-35 NP_001138755 (OMIM: 600018) mu-type opioid recepto ( 397) 917 148.4 2.8e-35 NP_001138756 (OMIM: 600018) mu-type opioid recepto ( 403) 917 148.4 2.8e-35 NP_001138754 (OMIM: 600018) mu-type opioid recepto ( 406) 917 148.4 2.8e-35 NP_001272452 (OMIM: 600018) mu-type opioid recepto ( 414) 917 148.4 2.9e-35 NP_001008503 (OMIM: 600018) mu-type opioid recepto ( 418) 917 148.4 2.9e-35 NP_001138758 (OMIM: 600018) mu-type opioid recepto ( 420) 917 148.4 2.9e-35 NP_001008505 (OMIM: 600018) mu-type opioid recepto ( 446) 917 148.5 3e-35 NP_000902 (OMIM: 165195) delta-type opioid recepto ( 372) 890 144.3 4.4e-34 NP_000903 (OMIM: 165196) kappa-type opioid recepto ( 380) 878 142.6 1.5e-33 NP_001305426 (OMIM: 165196) kappa-type opioid rece ( 409) 878 142.6 1.6e-33 NP_872588 (OMIM: 602548) nociceptin receptor isofo ( 370) 841 137.0 6.9e-32 XP_016883343 (OMIM: 602548) PREDICTED: nociceptin ( 370) 841 137.0 6.9e-32 NP_000904 (OMIM: 602548) nociceptin receptor isofo ( 370) 841 137.0 6.9e-32 NP_001186948 (OMIM: 602548) nociceptin receptor is ( 370) 841 137.0 6.9e-32 XP_016883342 (OMIM: 602548) PREDICTED: nociceptin ( 388) 841 137.1 7.1e-32 XP_011527130 (OMIM: 602548) PREDICTED: nociceptin ( 388) 841 137.1 7.1e-32 XP_016883341 (OMIM: 602548) PREDICTED: nociceptin ( 388) 841 137.1 7.1e-32 NP_001305782 (OMIM: 602548) nociceptin receptor is ( 399) 841 137.1 7.3e-32 NP_005277 (OMIM: 600731) neuropeptides B/W recepto ( 333) 804 131.5 2.9e-30 XP_016883344 (OMIM: 602548) PREDICTED: nociceptin ( 365) 791 129.6 1.2e-29 NP_001305783 (OMIM: 602548) nociceptin receptor is ( 365) 791 129.6 1.2e-29 NP_001138753 (OMIM: 600018) mu-type opioid recepto ( 319) 781 128.0 3.1e-29 NP_005276 (OMIM: 600730) neuropeptides B/W recepto ( 328) 780 127.9 3.5e-29 XP_016866395 (OMIM: 600018) PREDICTED: mu-type opi ( 300) 760 124.9 2.6e-28 NP_001138752 (OMIM: 600018) mu-type opioid recepto ( 300) 760 124.9 2.6e-28 NP_001138759 (OMIM: 600018) mu-type opioid recepto ( 300) 760 124.9 2.6e-28 NP_001272455 (OMIM: 600018) mu-type opioid recepto ( 300) 760 124.9 2.6e-28 NP_001272456 (OMIM: 600018) mu-type opioid recepto ( 292) 754 124.0 4.7e-28 NP_001272457 (OMIM: 600018) mu-type opioid recepto ( 314) 754 124.0 5e-28 XP_011534164 (OMIM: 600018) PREDICTED: mu-type opi ( 346) 754 124.0 5.3e-28 XP_011534158 (OMIM: 600018) PREDICTED: mu-type opi ( 346) 754 124.0 5.3e-28 XP_011534153 (OMIM: 600018) PREDICTED: mu-type opi ( 346) 754 124.0 5.3e-28 XP_016866392 (OMIM: 600018) PREDICTED: mu-type opi ( 346) 754 124.0 5.3e-28 >>NP_001040 (OMIM: 182451) somatostatin receptor type 1 (391 aa) initn: 2580 init1: 2580 opt: 2580 Z-score: 2094.8 bits: 396.4 E(85289): 6e-110 Smith-Waterman score: 2580; 100.0% identity (100.0% similar) in 391 aa overlap (1-391:1-391) 10 20 30 40 50 60 pF1KB4 MFPNGTASSPSSSPSPSPGSCGEGGGSRGPGAGAADGMEEPGRNASQNGTLSEGQGSAIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MFPNGTASSPSSSPSPSPGSCGEGGGSRGPGAGAADGMEEPGRNASQNGTLSEGQGSAIL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 ISFIYSVVCLVGLCGNSMVIYVILRYAKMKTATNIYILNLAIADELLMLSVPFLVTSTLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ISFIYSVVCLVGLCGNSMVIYVILRYAKMKTATNIYILNLAIADELLMLSVPFLVTSTLL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 RHWPFGALLCRLVLSVDAVNMFTSIYCLTVLSVDRYVAVVHPIKAARYRRPTVAKVVNLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RHWPFGALLCRLVLSVDAVNMFTSIYCLTVLSVDRYVAVVHPIKAARYRRPTVAKVVNLG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 VWVLSLLVILPIVVFSRTAANSDGTVACNMLMPEPAQRWLVGFVLYTFLMGFLLPVGAIC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VWVLSLLVILPIVVFSRTAANSDGTVACNMLMPEPAQRWLVGFVLYTFLMGFLLPVGAIC 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 LCYVLIIAKMRMVALKAGWQQRKRSERKITLMVMMVVMVFVICWMPFYVVQLVNVFAEQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LCYVLIIAKMRMVALKAGWQQRKRSERKITLMVMMVVMVFVICWMPFYVVQLVNVFAEQD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 DATVSQLSVILGYANSCANPILYGFLSDNFKRSFQRILCLSWMDNAAEEPVDYYATALKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DATVSQLSVILGYANSCANPILYGFLSDNFKRSFQRILCLSWMDNAAEEPVDYYATALKS 310 320 330 340 350 360 370 380 390 pF1KB4 RAYSVEDFQPENLESGGVFRNGTCTSRITTL ::::::::::::::::::::::::::::::: NP_001 RAYSVEDFQPENLESGGVFRNGTCTSRITTL 370 380 390 >>NP_001043 (OMIM: 182454) somatostatin receptor type 4 (388 aa) initn: 1408 init1: 709 opt: 1463 Z-score: 1194.6 bits: 229.8 E(85289): 8.5e-60 Smith-Waterman score: 1463; 62.9% identity (83.4% similar) in 356 aa overlap (12-361:2-354) 10 20 30 40 50 60 pF1KB4 MFPNGTASSPSSSPSPSPGSCGEGGGSRGPGAGAADGMEEPGRNASQNGTLSEGQGSAIL :.:: : . :: :. :.:. :.. ...: . ... : . NP_001 MSAPSTLPPGGEEGLGTAWPSAANASSAPAEAEEAVAGPGDARAAG-MVA 10 20 30 40 70 80 90 100 110 120 pF1KB4 ISFIYSVVCLVGLCGNSMVIYVILRYAKMKTATNIYILNLAIADELLMLSVPFLVTSTLL :. ::..:::::: ::..::.:::::::::::::::.::::.::::.::::::...:. : NP_001 IQCIYALVCLVGLVGNALVIFVILRYAKMKTATNIYLLNLAVADELFMLSVPFVASSAAL 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB4 RHWPFGALLCRLVLSVDAVNMFTSIYCLTVLSVDRYVAVVHPIKAARYRRPTVAKVVNLG ::::::..::: :::::..:::::..::::::::::::::::..:: ::::.:::..::: NP_001 RHWPFGSVLCRAVLSVDGLNMFTSVFCLTVLSVDRYVAVVHPLRAATYRRPSVAKLINLG 110 120 130 140 150 160 190 200 210 220 230 pF1KB4 VWVLSLLVILPIVVFSRTAANSDG-TVACNMLMPEPAQRWLVGFVLYTFLMGFLLPVGAI ::. :::: :::..:. : : .::::. :.:: : . ::.::::.:::::: :: NP_001 VWLASLLVTLPIAIFADTRPARGGQAVACNLQWPHPA--WSAVFVVYTFLLGFLLPVLAI 170 180 190 200 210 220 240 250 260 270 280 290 pF1KB4 CLCYVLIIAKMRMVALKAGWQQRKRSERKITLMVMMVVMVFVICWMPFYVVQLVNVFAEQ :::.::..::: :::.::::::.:::.::: .:.:::.:::.::::::::::.:.:. . NP_001 GLCYLLIVGKMRAVALRAGWQQRRRSEKKITRLVLMVVVVFVLCWMPFYVVQLLNLFVTS 230 240 250 260 270 280 300 310 320 330 340 350 pF1KB4 DDATVSQLSVILGYANSCANPILYGFLSDNFKRSFQRILCLS-----WMDNAAEEPVDYY ::::...:.::.::::::::::::::::::.: :::.::: .: :::.::: NP_001 LDATVNHVSLILSYANSCANPILYGFLSDNFRRFFQRVLCLRCCLLEGAGGAEEEPLDYY 290 300 310 320 330 340 360 370 380 390 pF1KB4 ATALKSRAYSVEDFQPENLESGGVFRNGTCTSRITTL ::::::. NP_001 ATALKSKGGAGCMCPPLPCQQEALQPEPGRKRIPLTRTTTF 350 360 370 380 >>NP_001041 (OMIM: 182452) somatostatin receptor type 2 (369 aa) initn: 1158 init1: 986 opt: 1143 Z-score: 936.9 bits: 182.1 E(85289): 1.9e-45 Smith-Waterman score: 1143; 55.6% identity (83.3% similar) in 288 aa overlap (57-340:42-329) 30 40 50 60 70 80 pF1KB4 SRGPGAGAADGMEEPGRNASQNGTLSEGQGSAILISFIYSVVCLVGLCGNSMVIYVILRY : ...::: :::..:::::..:::::::: NP_001 HTWLSIPFDLNGSVVSTNTSNQTEPYYDLTSNAVLTFIYFVVCIIGLCGNTLVIYVILRY 20 30 40 50 60 70 90 100 110 120 130 140 pF1KB4 AKMKTATNIYILNLAIADELLMLSVPFLVTSTLLRHWPFGALLCRLVLSVDAVNMFTSIY ::::: ::::::::::::::.::..:::. .. : ::::: .::.:..::..:.::::. NP_001 AKMKTITNIYILNLAIADELFMLGLPFLAMQVALVHWPFGKAICRVVMTVDGINQFTSIF 80 90 100 110 120 130 150 160 170 180 190 200 pF1KB4 CLTVLSVDRYVAVVHPIKAARYRRPTVAKVVNLGVWVLSLLVILPIVVFSRTAANSDGTV ::::.:.:::.:::::::.:..::: .::.....:: .::::::::.... .:. : NP_001 CLTVMSIDRYLAVVHPIKSAKWRRPRTAKMITMAVWGVSLLVILPIMIYAGLRSNQWGRS 140 150 160 170 180 190 210 220 230 240 250 260 pF1KB4 ACNMLMPEPAQRWLVGFVLYTFLMGFLLPVGAICLCYVLIIAKMRMVALKAGWQQRKRSE .:.. : . : .::..:::..:::.:. :::::..:: :.. ....: ..::.:: NP_001 SCTINWPGESGAWYTGFIIYTFILGFLVPLTIICLCYLFIIIKVKSSGIRVGSSKRKKSE 200 210 220 230 240 250 270 280 290 300 310 320 pF1KB4 RKITLMVMMVVMVFVICWMPFYV--VQLVNVFAEQDDATVSQLS--VILGYANSCANPIL .:.: :: .:: ::..::.:::. :. :.. : .... :.: :::::::::: NP_001 KKVTRMVSIVVAVFIFCWLPFYIFNVSSVSMAISPTPALKGMFDFVVVLTYANSCANPIL 260 270 280 290 300 310 330 340 350 360 370 380 pF1KB4 YGFLSDNFKRSFQRILCLSWMDNAAEEPVDYYATALKSRAYSVEDFQPENLESGGVFRNG :.:::::::.::: .::: NP_001 YAFLSDNFKKSFQNVLCLVKVSGTDDGERSDSKQDKSRLNETTETQRTLLNGDLQTSI 320 330 340 350 360 >>NP_001166031 (OMIM: 182455) somatostatin receptor type (364 aa) initn: 1145 init1: 594 opt: 1087 Z-score: 891.8 bits: 173.7 E(85289): 6.2e-43 Smith-Waterman score: 1091; 49.9% identity (75.6% similar) in 349 aa overlap (10-350:6-335) 10 20 30 40 50 60 pF1KB4 MFPNGTASSPSSSPSPSPGSCGEGGGSRGPGAGAADGMEEPGRNASQNGTLSEGQGSAIL :.:.:: . .: ::: :. : : : . : . . :.: NP_001 MEPLFPASTPSWNASS---------PGA-ASGG----GDNRTLVGPAPSAGARAVL 10 20 30 40 70 80 90 100 110 120 pF1KB4 ISFIYSVVCLVGLCGNSMVIYVILRYAKMKTATNIYILNLAIADELLMLSVPFLVTSTLL . .: .:: .:: ::..::::.::.:::::.:::::::::.:: : ::..:::.:.. NP_001 VPVLYLLVCAAGLGGNTLVIYVVLRFAKMKTVTNIYILNLAVADVLYMLGLPFLATQNAA 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB4 RHWPFGALLCRLVLSVDAVNMFTSIYCLTVLSVDRYVAVVHPIKAARYRRPTVAKVVNLG :::: .:::::...:.::.:::..::::.:::::.:::::...::.::: :::... . NP_001 SFWPFGPVLCRLVMTLDGVNQFTSVFCLTVMSVDRYLAVVHPLSSARWRRPRVAKLASAA 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB4 VWVLSLLVILPIVVFSRTAANSDGTVACNMLMPEPAQRWLVGFVLYTFLMGFLLPVGAIC .::::: . ::..::. . . :: :: :::. : . :..:: ..::. :. .:: NP_001 AWVLSLCMSLPLLVFADV--QEGGT--CNASWPEPVGLWGAVFIIYTAVLGFFAPLLVIC 170 180 190 200 210 250 260 270 280 290 pF1KB4 LCYVLIIAKMRMVALKAGWQQRKRSERKITLMVMMVVMVFVICWMPFYVVQLVN--VFAE :::.::..:.: .....: :.:::::.: ::..::.::. ::.::..:..:: : NP_001 LCYLLIVVKVRAAGVRVG-CVRRRSERKVTRMVLVVVLVFAGCWLPFFTVNIVNLAVALP 220 230 240 250 260 270 300 310 320 330 340 350 pF1KB4 QDDATVSQ--LSVILGYANSCANPILYGFLSDNFKRSFQRILCL----SWMDNAAEEPVD :. :... . :::.::::::::.:::::::::..:::..::: . : : :: NP_001 QEPASAGLYFFVVILSYANSCANPVLYGFLSDNFRQSFQKVLCLRKGSGAKDADATEPRP 280 290 300 310 320 330 360 370 380 390 pF1KB4 YYATALKSRAYSVEDFQPENLESGGVFRNGTCTSRITTL NP_001 DRIRQQQEATPPAHRAAANGLMQTSKL 340 350 360 >>NP_001044 (OMIM: 182455) somatostatin receptor type 5 (364 aa) initn: 1145 init1: 594 opt: 1087 Z-score: 891.8 bits: 173.7 E(85289): 6.2e-43 Smith-Waterman score: 1091; 49.9% identity (75.6% similar) in 349 aa overlap (10-350:6-335) 10 20 30 40 50 60 pF1KB4 MFPNGTASSPSSSPSPSPGSCGEGGGSRGPGAGAADGMEEPGRNASQNGTLSEGQGSAIL :.:.:: . .: ::: :. : : : . : . . :.: NP_001 MEPLFPASTPSWNASS---------PGA-ASGG----GDNRTLVGPAPSAGARAVL 10 20 30 40 70 80 90 100 110 120 pF1KB4 ISFIYSVVCLVGLCGNSMVIYVILRYAKMKTATNIYILNLAIADELLMLSVPFLVTSTLL . .: .:: .:: ::..::::.::.:::::.:::::::::.:: : ::..:::.:.. NP_001 VPVLYLLVCAAGLGGNTLVIYVVLRFAKMKTVTNIYILNLAVADVLYMLGLPFLATQNAA 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB4 RHWPFGALLCRLVLSVDAVNMFTSIYCLTVLSVDRYVAVVHPIKAARYRRPTVAKVVNLG :::: .:::::...:.::.:::..::::.:::::.:::::...::.::: :::... . NP_001 SFWPFGPVLCRLVMTLDGVNQFTSVFCLTVMSVDRYLAVVHPLSSARWRRPRVAKLASAA 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB4 VWVLSLLVILPIVVFSRTAANSDGTVACNMLMPEPAQRWLVGFVLYTFLMGFLLPVGAIC .::::: . ::..::. . . :: :: :::. : . :..:: ..::. :. .:: NP_001 AWVLSLCMSLPLLVFADV--QEGGT--CNASWPEPVGLWGAVFIIYTAVLGFFAPLLVIC 170 180 190 200 210 250 260 270 280 290 pF1KB4 LCYVLIIAKMRMVALKAGWQQRKRSERKITLMVMMVVMVFVICWMPFYVVQLVN--VFAE :::.::..:.: .....: :.:::::.: ::..::.::. ::.::..:..:: : NP_001 LCYLLIVVKVRAAGVRVG-CVRRRSERKVTRMVLVVVLVFAGCWLPFFTVNIVNLAVALP 220 230 240 250 260 270 300 310 320 330 340 350 pF1KB4 QDDATVSQ--LSVILGYANSCANPILYGFLSDNFKRSFQRILCL----SWMDNAAEEPVD :. :... . :::.::::::::.:::::::::..:::..::: . : : :: NP_001 QEPASAGLYFFVVILSYANSCANPVLYGFLSDNFRQSFQKVLCLRKGSGAKDADATEPRP 280 290 300 310 320 330 360 370 380 390 pF1KB4 YYATALKSRAYSVEDFQPENLESGGVFRNGTCTSRITTL NP_001 DRIRQQQEATPPAHRAAANGLMQTSKL 340 350 360 >>XP_016884412 (OMIM: 182453) PREDICTED: somatostatin re (418 aa) initn: 859 init1: 723 opt: 1049 Z-score: 860.5 bits: 168.1 E(85289): 3.4e-41 Smith-Waterman score: 1049; 49.5% identity (76.0% similar) in 329 aa overlap (57-377:43-365) 30 40 50 60 70 80 pF1KB4 SRGPGAGAADGMEEPGRNASQNGTLSEGQGSAILISFIYSVVCLVGLCGNSMVIYVILRY :..:: ..: :::.::: :::.::::.::. XP_016 SEPENASSAWPPDATLGNVSAGPSPAGLAVSGVLIPLVYLVVCVVGLLGNSLVIYVVLRH 20 30 40 50 60 70 90 100 110 120 130 140 pF1KB4 AKMKTATNIYILNLAIADELLMLSVPFLVTSTLLRHWPFGALLCRLVLSVDAVNMFTSIY . ..::.::::::.::::.::..:::.... : .::::.:.::::..::..:.::::. XP_016 TASPSVTNVYILNLALADELFMLGLPFLAAQNALSYWPFGSLMCRLVMAVDGINQFTSIF 80 90 100 110 120 130 150 160 170 180 190 200 pF1KB4 CLTVLSVDRYVAVVHPIKAARYRRPTVAKVVNLGVWVLSLLVILPIVVFSRTAANSDGTV ::::.:::::.::::: ..::.: ::..:. .::: : .:.::.:::: . : XP_016 CLTVMSVDRYLAVVHPTRSARWRTAPVARTVSAAVWVASAVVVLPVVVFSGV---PRGMS 140 150 160 170 180 210 220 230 240 250 260 pF1KB4 ACNMLMPEPAQRWLVGFVLYTFLMGFLLPVGAICLCYVLIIAKMRMVALKAGW----QQR .:.: :::: : .::..:: .::. :. .:::::.::..:.: .. .. : :.: XP_016 TCHMQWPEPAAAWRAGFIIYTAALGFFGPLLVICLCYLLIVVKVRSAGRRV-WAPSCQRR 190 200 210 220 230 240 270 280 290 300 310 pF1KB4 KRSERKITLMVMMVVMVFVICWMPFYVVQLVNVFAE--QDDATVSQ--LSVILGYANSCA .::::..: ::. :: .::.:::::::...::: .. : . : : : :::::: XP_016 RRSERRVTRMVVAVVALFVLCWMPFYVLNIVNVVCPLPEEPAFFGLYFLVVALPYANSCA 250 260 270 280 290 300 320 330 340 350 360 370 pF1KB4 NPILYGFLSDNFKRSFQRILCLSWMDNAAEEPVDYYATALKSRAYSVEDFQPENLESGGV ::::::::: ::..:.:.: ..::. . :.. . :. . :. . :: XP_016 NPILYGFLSYRFKQGFRRVLLRPSRRVRSQEPT--VGPPEKTEEEDEEEEDGEESREGGK 310 320 330 340 350 360 380 390 pF1KB4 FRNGTCTSRITTL XP_016 GKEMNGRVSQITQPGTSGQERPPSRVASKEQQLLPQEASTGEKSSTMRISYL 370 380 390 400 410 >>NP_001042 (OMIM: 182453) somatostatin receptor type 3 (418 aa) initn: 859 init1: 723 opt: 1049 Z-score: 860.5 bits: 168.1 E(85289): 3.4e-41 Smith-Waterman score: 1049; 49.5% identity (76.0% similar) in 329 aa overlap (57-377:43-365) 30 40 50 60 70 80 pF1KB4 SRGPGAGAADGMEEPGRNASQNGTLSEGQGSAILISFIYSVVCLVGLCGNSMVIYVILRY :..:: ..: :::.::: :::.::::.::. NP_001 SEPENASSAWPPDATLGNVSAGPSPAGLAVSGVLIPLVYLVVCVVGLLGNSLVIYVVLRH 20 30 40 50 60 70 90 100 110 120 130 140 pF1KB4 AKMKTATNIYILNLAIADELLMLSVPFLVTSTLLRHWPFGALLCRLVLSVDAVNMFTSIY . ..::.::::::.::::.::..:::.... : .::::.:.::::..::..:.::::. NP_001 TASPSVTNVYILNLALADELFMLGLPFLAAQNALSYWPFGSLMCRLVMAVDGINQFTSIF 80 90 100 110 120 130 150 160 170 180 190 200 pF1KB4 CLTVLSVDRYVAVVHPIKAARYRRPTVAKVVNLGVWVLSLLVILPIVVFSRTAANSDGTV ::::.:::::.::::: ..::.: ::..:. .::: : .:.::.:::: . : NP_001 CLTVMSVDRYLAVVHPTRSARWRTAPVARTVSAAVWVASAVVVLPVVVFSGV---PRGMS 140 150 160 170 180 210 220 230 240 250 260 pF1KB4 ACNMLMPEPAQRWLVGFVLYTFLMGFLLPVGAICLCYVLIIAKMRMVALKAGW----QQR .:.: :::: : .::..:: .::. :. .:::::.::..:.: .. .. : :.: NP_001 TCHMQWPEPAAAWRAGFIIYTAALGFFGPLLVICLCYLLIVVKVRSAGRRV-WAPSCQRR 190 200 210 220 230 240 270 280 290 300 310 pF1KB4 KRSERKITLMVMMVVMVFVICWMPFYVVQLVNVFAE--QDDATVSQ--LSVILGYANSCA .::::..: ::. :: .::.:::::::...::: .. : . : : : :::::: NP_001 RRSERRVTRMVVAVVALFVLCWMPFYVLNIVNVVCPLPEEPAFFGLYFLVVALPYANSCA 250 260 270 280 290 300 320 330 340 350 360 370 pF1KB4 NPILYGFLSDNFKRSFQRILCLSWMDNAAEEPVDYYATALKSRAYSVEDFQPENLESGGV ::::::::: ::..:.:.: ..::. . :.. . :. . :. . :: NP_001 NPILYGFLSYRFKQGFRRVLLRPSRRVRSQEPT--VGPPEKTEEEDEEEEDGEESREGGK 310 320 330 340 350 360 380 390 pF1KB4 FRNGTCTSRITTL NP_001 GKEMNGRVSQITQPGTSGQERPPSRVASKEQQLLPQEASTGEKSSTMRISYL 370 380 390 400 410 >>XP_016884413 (OMIM: 182453) PREDICTED: somatostatin re (418 aa) initn: 859 init1: 723 opt: 1049 Z-score: 860.5 bits: 168.1 E(85289): 3.4e-41 Smith-Waterman score: 1049; 49.5% identity (76.0% similar) in 329 aa overlap (57-377:43-365) 30 40 50 60 70 80 pF1KB4 SRGPGAGAADGMEEPGRNASQNGTLSEGQGSAILISFIYSVVCLVGLCGNSMVIYVILRY :..:: ..: :::.::: :::.::::.::. XP_016 SEPENASSAWPPDATLGNVSAGPSPAGLAVSGVLIPLVYLVVCVVGLLGNSLVIYVVLRH 20 30 40 50 60 70 90 100 110 120 130 140 pF1KB4 AKMKTATNIYILNLAIADELLMLSVPFLVTSTLLRHWPFGALLCRLVLSVDAVNMFTSIY . ..::.::::::.::::.::..:::.... : .::::.:.::::..::..:.::::. XP_016 TASPSVTNVYILNLALADELFMLGLPFLAAQNALSYWPFGSLMCRLVMAVDGINQFTSIF 80 90 100 110 120 130 150 160 170 180 190 200 pF1KB4 CLTVLSVDRYVAVVHPIKAARYRRPTVAKVVNLGVWVLSLLVILPIVVFSRTAANSDGTV ::::.:::::.::::: ..::.: ::..:. .::: : .:.::.:::: . : XP_016 CLTVMSVDRYLAVVHPTRSARWRTAPVARTVSAAVWVASAVVVLPVVVFSGV---PRGMS 140 150 160 170 180 210 220 230 240 250 260 pF1KB4 ACNMLMPEPAQRWLVGFVLYTFLMGFLLPVGAICLCYVLIIAKMRMVALKAGW----QQR .:.: :::: : .::..:: .::. :. .:::::.::..:.: .. .. : :.: XP_016 TCHMQWPEPAAAWRAGFIIYTAALGFFGPLLVICLCYLLIVVKVRSAGRRV-WAPSCQRR 190 200 210 220 230 240 270 280 290 300 310 pF1KB4 KRSERKITLMVMMVVMVFVICWMPFYVVQLVNVFAE--QDDATVSQ--LSVILGYANSCA .::::..: ::. :: .::.:::::::...::: .. : . : : : :::::: XP_016 RRSERRVTRMVVAVVALFVLCWMPFYVLNIVNVVCPLPEEPAFFGLYFLVVALPYANSCA 250 260 270 280 290 300 320 330 340 350 360 370 pF1KB4 NPILYGFLSDNFKRSFQRILCLSWMDNAAEEPVDYYATALKSRAYSVEDFQPENLESGGV ::::::::: ::..:.:.: ..::. . :.. . :. . :. . :: XP_016 NPILYGFLSYRFKQGFRRVLLRPSRRVRSQEPT--VGPPEKTEEEDEEEEDGEESREGGK 310 320 330 340 350 360 380 390 pF1KB4 FRNGTCTSRITTL XP_016 GKEMNGRVSQITQPGTSGQERPPSRVASKEQQLLPQEASTGEKSSTMRISYL 370 380 390 400 410 >>XP_005261778 (OMIM: 182453) PREDICTED: somatostatin re (418 aa) initn: 859 init1: 723 opt: 1049 Z-score: 860.5 bits: 168.1 E(85289): 3.4e-41 Smith-Waterman score: 1049; 49.5% identity (76.0% similar) in 329 aa overlap (57-377:43-365) 30 40 50 60 70 80 pF1KB4 SRGPGAGAADGMEEPGRNASQNGTLSEGQGSAILISFIYSVVCLVGLCGNSMVIYVILRY :..:: ..: :::.::: :::.::::.::. XP_005 SEPENASSAWPPDATLGNVSAGPSPAGLAVSGVLIPLVYLVVCVVGLLGNSLVIYVVLRH 20 30 40 50 60 70 90 100 110 120 130 140 pF1KB4 AKMKTATNIYILNLAIADELLMLSVPFLVTSTLLRHWPFGALLCRLVLSVDAVNMFTSIY . ..::.::::::.::::.::..:::.... : .::::.:.::::..::..:.::::. XP_005 TASPSVTNVYILNLALADELFMLGLPFLAAQNALSYWPFGSLMCRLVMAVDGINQFTSIF 80 90 100 110 120 130 150 160 170 180 190 200 pF1KB4 CLTVLSVDRYVAVVHPIKAARYRRPTVAKVVNLGVWVLSLLVILPIVVFSRTAANSDGTV ::::.:::::.::::: ..::.: ::..:. .::: : .:.::.:::: . : XP_005 CLTVMSVDRYLAVVHPTRSARWRTAPVARTVSAAVWVASAVVVLPVVVFSGV---PRGMS 140 150 160 170 180 210 220 230 240 250 260 pF1KB4 ACNMLMPEPAQRWLVGFVLYTFLMGFLLPVGAICLCYVLIIAKMRMVALKAGW----QQR .:.: :::: : .::..:: .::. :. .:::::.::..:.: .. .. : :.: XP_005 TCHMQWPEPAAAWRAGFIIYTAALGFFGPLLVICLCYLLIVVKVRSAGRRV-WAPSCQRR 190 200 210 220 230 240 270 280 290 300 310 pF1KB4 KRSERKITLMVMMVVMVFVICWMPFYVVQLVNVFAE--QDDATVSQ--LSVILGYANSCA .::::..: ::. :: .::.:::::::...::: .. : . : : : :::::: XP_005 RRSERRVTRMVVAVVALFVLCWMPFYVLNIVNVVCPLPEEPAFFGLYFLVVALPYANSCA 250 260 270 280 290 300 320 330 340 350 360 370 pF1KB4 NPILYGFLSDNFKRSFQRILCLSWMDNAAEEPVDYYATALKSRAYSVEDFQPENLESGGV ::::::::: ::..:.:.: ..::. . :.. . :. . :. . :: XP_005 NPILYGFLSYRFKQGFRRVLLRPSRRVRSQEPT--VGPPEKTEEEDEEEEDGEESREGGK 310 320 330 340 350 360 380 390 pF1KB4 FRNGTCTSRITTL XP_005 GKEMNGRVSQITQPGTSGQERPPSRVASKEQQLLPQEASTGEKSSTMRISYL 370 380 390 400 410 >>XP_006724374 (OMIM: 182453) PREDICTED: somatostatin re (418 aa) initn: 859 init1: 723 opt: 1049 Z-score: 860.5 bits: 168.1 E(85289): 3.4e-41 Smith-Waterman score: 1049; 49.5% identity (76.0% similar) in 329 aa overlap (57-377:43-365) 30 40 50 60 70 80 pF1KB4 SRGPGAGAADGMEEPGRNASQNGTLSEGQGSAILISFIYSVVCLVGLCGNSMVIYVILRY :..:: ..: :::.::: :::.::::.::. XP_006 SEPENASSAWPPDATLGNVSAGPSPAGLAVSGVLIPLVYLVVCVVGLLGNSLVIYVVLRH 20 30 40 50 60 70 90 100 110 120 130 140 pF1KB4 AKMKTATNIYILNLAIADELLMLSVPFLVTSTLLRHWPFGALLCRLVLSVDAVNMFTSIY . ..::.::::::.::::.::..:::.... : .::::.:.::::..::..:.::::. XP_006 TASPSVTNVYILNLALADELFMLGLPFLAAQNALSYWPFGSLMCRLVMAVDGINQFTSIF 80 90 100 110 120 130 150 160 170 180 190 200 pF1KB4 CLTVLSVDRYVAVVHPIKAARYRRPTVAKVVNLGVWVLSLLVILPIVVFSRTAANSDGTV ::::.:::::.::::: ..::.: ::..:. .::: : .:.::.:::: . : XP_006 CLTVMSVDRYLAVVHPTRSARWRTAPVARTVSAAVWVASAVVVLPVVVFSGV---PRGMS 140 150 160 170 180 210 220 230 240 250 260 pF1KB4 ACNMLMPEPAQRWLVGFVLYTFLMGFLLPVGAICLCYVLIIAKMRMVALKAGW----QQR .:.: :::: : .::..:: .::. :. .:::::.::..:.: .. .. : :.: XP_006 TCHMQWPEPAAAWRAGFIIYTAALGFFGPLLVICLCYLLIVVKVRSAGRRV-WAPSCQRR 190 200 210 220 230 240 270 280 290 300 310 pF1KB4 KRSERKITLMVMMVVMVFVICWMPFYVVQLVNVFAE--QDDATVSQ--LSVILGYANSCA .::::..: ::. :: .::.:::::::...::: .. : . : : : :::::: XP_006 RRSERRVTRMVVAVVALFVLCWMPFYVLNIVNVVCPLPEEPAFFGLYFLVVALPYANSCA 250 260 270 280 290 300 320 330 340 350 360 370 pF1KB4 NPILYGFLSDNFKRSFQRILCLSWMDNAAEEPVDYYATALKSRAYSVEDFQPENLESGGV ::::::::: ::..:.:.: ..::. . :.. . :. . :. . :: XP_006 NPILYGFLSYRFKQGFRRVLLRPSRRVRSQEPT--VGPPEKTEEEDEEEEDGEESREGGK 310 320 330 340 350 360 380 390 pF1KB4 FRNGTCTSRITTL XP_006 GKEMNGRVSQITQPGTSGQERPPSRVASKEQQLLPQEASTGEKSSTMRISYL 370 380 390 400 410 391 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 14:52:37 2016 done: Thu Nov 3 14:52:38 2016 Total Scan time: 9.000 Total Display time: 0.060 Function used was FASTA [36.3.4 Apr, 2011]