FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB4391, 520 aa 1>>>pF1KB4391 520 - 520 aa - 520 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.7345+/-0.000426; mu= 16.5689+/- 0.026 mean_var=89.9969+/-17.810, 0's: 0 Z-trim(112.8): 288 B-trim: 14 in 1/50 Lambda= 0.135195 statistics sampled from 21554 (21863) to 21554 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.622), E-opt: 0.2 (0.256), width: 16 Scan time: 9.120 The best scores are: opt bits E(85289) NP_006528 (OMIM: 604728) ubiquitin carboxyl-termin ( 520) 3589 710.6 2.8e-204 XP_016878253 (OMIM: 604728) PREDICTED: ubiquitin c ( 498) 3358 665.6 9.8e-191 XP_016878252 (OMIM: 604728) PREDICTED: ubiquitin c ( 498) 3358 665.6 9.8e-191 XP_016878254 (OMIM: 604728) PREDICTED: ubiquitin c ( 498) 3358 665.6 9.8e-191 XP_016878256 (OMIM: 604728) PREDICTED: ubiquitin c ( 435) 2954 586.7 4.6e-167 XP_016878255 (OMIM: 604728) PREDICTED: ubiquitin c ( 435) 2954 586.7 4.6e-167 NP_001243631 (OMIM: 604728) ubiquitin carboxyl-ter ( 476) 2913 578.8 1.3e-164 XP_016878257 (OMIM: 604728) PREDICTED: ubiquitin c ( 351) 2397 478.0 2e-134 XP_016875500 (OMIM: 610993) PREDICTED: ubiquitin c ( 712) 602 128.1 8.5e-29 NP_001035862 (OMIM: 610993) ubiquitin carboxyl-ter ( 712) 602 128.1 8.5e-29 XP_016875498 (OMIM: 610993) PREDICTED: ubiquitin c ( 712) 602 128.1 8.5e-29 XP_016875499 (OMIM: 610993) PREDICTED: ubiquitin c ( 712) 602 128.1 8.5e-29 NP_115523 (OMIM: 610993) ubiquitin carboxyl-termin ( 712) 602 128.1 8.5e-29 NP_001265322 (OMIM: 610993) ubiquitin carboxyl-ter ( 712) 602 128.1 8.5e-29 XP_016874028 (OMIM: 604725) PREDICTED: ubiquitin c ( 352) 487 105.5 2.8e-22 NP_001230688 (OMIM: 604725) ubiquitin carboxyl-ter ( 362) 487 105.5 2.8e-22 NP_741994 (OMIM: 604725) ubiquitin carboxyl-termin ( 396) 487 105.5 3e-22 XP_005271779 (OMIM: 604725) PREDICTED: ubiquitin c ( 605) 487 105.7 4.2e-22 NP_004196 (OMIM: 604725) ubiquitin carboxyl-termin ( 605) 487 105.7 4.2e-22 XP_005271778 (OMIM: 604725) PREDICTED: ubiquitin c ( 605) 487 105.7 4.2e-22 XP_016878210 (OMIM: 603158) PREDICTED: ubiquitin c ( 928) 484 105.2 8.8e-22 XP_016878211 (OMIM: 603158) PREDICTED: ubiquitin c ( 928) 484 105.2 8.8e-22 NP_001269978 (OMIM: 603158) ubiquitin carboxyl-ter (1012) 484 105.2 9.4e-22 XP_016878209 (OMIM: 603158) PREDICTED: ubiquitin c (1089) 484 105.3 1e-21 XP_006720825 (OMIM: 603158) PREDICTED: ubiquitin c (1089) 484 105.3 1e-21 XP_016878208 (OMIM: 603158) PREDICTED: ubiquitin c (1089) 484 105.3 1e-21 XP_016878207 (OMIM: 603158) PREDICTED: ubiquitin c (1089) 484 105.3 1e-21 XP_011520495 (OMIM: 603158) PREDICTED: ubiquitin c (1118) 484 105.3 1e-21 NP_005145 (OMIM: 603158) ubiquitin carboxyl-termin (1118) 484 105.3 1e-21 NP_001122082 (OMIM: 603158) ubiquitin carboxyl-ter (1118) 484 105.3 1e-21 XP_006720824 (OMIM: 603158) PREDICTED: ubiquitin c (1118) 484 105.3 1e-21 XP_005269318 (OMIM: 604731) PREDICTED: ubiquitin c ( 648) 479 104.1 1.3e-21 XP_016875774 (OMIM: 604731) PREDICTED: ubiquitin c ( 860) 479 104.2 1.6e-21 XP_016875773 (OMIM: 604731) PREDICTED: ubiquitin c ( 860) 479 104.2 1.6e-21 NP_006304 (OMIM: 604731) ubiquitin carboxyl-termin ( 952) 479 104.2 1.8e-21 NP_001239007 (OMIM: 604731) ubiquitin carboxyl-ter ( 981) 479 104.2 1.8e-21 NP_955475 (OMIM: 603486) ubiquitin carboxyl-termin ( 916) 466 101.7 9.9e-21 NP_003354 (OMIM: 603486) ubiquitin carboxyl-termin ( 963) 466 101.7 1e-20 NP_036607 (OMIM: 604729) ubiquitin carboxyl-termin ( 565) 452 98.8 4.5e-20 NP_001014443 (OMIM: 604729) ubiquitin carboxyl-ter ( 565) 452 98.8 4.5e-20 XP_016856529 (OMIM: 604729) PREDICTED: ubiquitin c ( 594) 452 98.8 4.7e-20 NP_001306776 (OMIM: 604729) ubiquitin carboxyl-ter ( 594) 452 98.8 4.7e-20 XP_016856217 (OMIM: 615146) PREDICTED: ubiquitin c ( 763) 429 94.4 1.3e-18 XP_016856216 (OMIM: 615146) PREDICTED: ubiquitin c ( 763) 429 94.4 1.3e-18 XP_016856213 (OMIM: 615146) PREDICTED: ubiquitin c ( 812) 429 94.4 1.3e-18 XP_016856212 (OMIM: 615146) PREDICTED: ubiquitin c ( 820) 429 94.4 1.4e-18 NP_963920 (OMIM: 615146) ubiquitin carboxyl-termin ( 828) 429 94.4 1.4e-18 XP_005270706 (OMIM: 615146) PREDICTED: ubiquitin c ( 851) 429 94.4 1.4e-18 XP_016856211 (OMIM: 615146) PREDICTED: ubiquitin c ( 903) 429 94.5 1.5e-18 NP_963918 (OMIM: 615146) ubiquitin carboxyl-termin ( 911) 429 94.5 1.5e-18 >>NP_006528 (OMIM: 604728) ubiquitin carboxyl-terminal h (520 aa) initn: 3589 init1: 3589 opt: 3589 Z-score: 3788.5 bits: 710.6 E(85289): 2.8e-204 Smith-Waterman score: 3589; 100.0% identity (100.0% similar) in 520 aa overlap (1-520:1-520) 10 20 30 40 50 60 pF1KB4 MECPHLSSSVCIAPDSAKFPNGSPSSWCCSVCRSNKSPWVCLTCSSVHCGRYVNGHAKKH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 MECPHLSSSVCIAPDSAKFPNGSPSSWCCSVCRSNKSPWVCLTCSSVHCGRYVNGHAKKH 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 YEDAQVPLTNHKKSEKQDKVQHTVCMDCSSYSTYCYRCDDFVVNDTKLGLVQKVREHLQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 YEDAQVPLTNHKKSEKQDKVQHTVCMDCSSYSTYCYRCDDFVVNDTKLGLVQKVREHLQN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 LENSAFTADRHKKRKLLENSTLNSKLLKVNGSTTAICATGLRNLGNTCFMNAILQSLSNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 LENSAFTADRHKKRKLLENSTLNSKLLKVNGSTTAICATGLRNLGNTCFMNAILQSLSNI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 EQFCCYFKELPAVELRNGKTAGRRTYHTRSQGDNNVSLVEEFRKTLCALWQGSQTAFSPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 EQFCCYFKELPAVELRNGKTAGRRTYHTRSQGDNNVSLVEEFRKTLCALWQGSQTAFSPE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 SLFYVVWKIMPNFRGYQQQDAHEFMRYLLDHLHLELQGGFNGVSRSAILQENSTLSASNK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 SLFYVVWKIMPNFRGYQQQDAHEFMRYLLDHLHLELQGGFNGVSRSAILQENSTLSASNK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 CCINGASTVVTAIFGGILQNEVNCLICGTESRKFDPFLDLSLDIPSQFRSKRSKNQENGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 CCINGASTVVTAIFGGILQNEVNCLICGTESRKFDPFLDLSLDIPSQFRSKRSKNQENGP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB4 VCSLRDCLRSFTDLEELDETELYMCHKCKKKQKSTKKFWIQKLPKVLCLHLKRFHWTAYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 VCSLRDCLRSFTDLEELDETELYMCHKCKKKQKSTKKFWIQKLPKVLCLHLKRFHWTAYL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB4 RNKVDTYVEFPLRGLDMKCYLLEPENSGPESCLYDLAAVVVHHGSGVGSGHYTAYATHEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 RNKVDTYVEFPLRGLDMKCYLLEPENSGPESCLYDLAAVVVHHGSGVGSGHYTAYATHEG 430 440 450 460 470 480 490 500 510 520 pF1KB4 RWFHFNDSTVTLTDEETVVKAKAYILFYVEHQAKAGSDKL :::::::::::::::::::::::::::::::::::::::: NP_006 RWFHFNDSTVTLTDEETVVKAKAYILFYVEHQAKAGSDKL 490 500 510 520 >>XP_016878253 (OMIM: 604728) PREDICTED: ubiquitin carbo (498 aa) initn: 3358 init1: 3358 opt: 3358 Z-score: 3545.3 bits: 665.6 E(85289): 9.8e-191 Smith-Waterman score: 3358; 99.8% identity (100.0% similar) in 491 aa overlap (30-520:8-498) 10 20 30 40 50 60 pF1KB4 MECPHLSSSVCIAPDSAKFPNGSPSSWCCSVCRSNKSPWVCLTCSSVHCGRYVNGHAKKH .:::::::::::::::::::::::::::::: XP_016 MQSPPHLAVCRSNKSPWVCLTCSSVHCGRYVNGHAKKH 10 20 30 70 80 90 100 110 120 pF1KB4 YEDAQVPLTNHKKSEKQDKVQHTVCMDCSSYSTYCYRCDDFVVNDTKLGLVQKVREHLQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YEDAQVPLTNHKKSEKQDKVQHTVCMDCSSYSTYCYRCDDFVVNDTKLGLVQKVREHLQN 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB4 LENSAFTADRHKKRKLLENSTLNSKLLKVNGSTTAICATGLRNLGNTCFMNAILQSLSNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LENSAFTADRHKKRKLLENSTLNSKLLKVNGSTTAICATGLRNLGNTCFMNAILQSLSNI 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB4 EQFCCYFKELPAVELRNGKTAGRRTYHTRSQGDNNVSLVEEFRKTLCALWQGSQTAFSPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EQFCCYFKELPAVELRNGKTAGRRTYHTRSQGDNNVSLVEEFRKTLCALWQGSQTAFSPE 160 170 180 190 200 210 250 260 270 280 290 300 pF1KB4 SLFYVVWKIMPNFRGYQQQDAHEFMRYLLDHLHLELQGGFNGVSRSAILQENSTLSASNK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SLFYVVWKIMPNFRGYQQQDAHEFMRYLLDHLHLELQGGFNGVSRSAILQENSTLSASNK 220 230 240 250 260 270 310 320 330 340 350 360 pF1KB4 CCINGASTVVTAIFGGILQNEVNCLICGTESRKFDPFLDLSLDIPSQFRSKRSKNQENGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CCINGASTVVTAIFGGILQNEVNCLICGTESRKFDPFLDLSLDIPSQFRSKRSKNQENGP 280 290 300 310 320 330 370 380 390 400 410 420 pF1KB4 VCSLRDCLRSFTDLEELDETELYMCHKCKKKQKSTKKFWIQKLPKVLCLHLKRFHWTAYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VCSLRDCLRSFTDLEELDETELYMCHKCKKKQKSTKKFWIQKLPKVLCLHLKRFHWTAYL 340 350 360 370 380 390 430 440 450 460 470 480 pF1KB4 RNKVDTYVEFPLRGLDMKCYLLEPENSGPESCLYDLAAVVVHHGSGVGSGHYTAYATHEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RNKVDTYVEFPLRGLDMKCYLLEPENSGPESCLYDLAAVVVHHGSGVGSGHYTAYATHEG 400 410 420 430 440 450 490 500 510 520 pF1KB4 RWFHFNDSTVTLTDEETVVKAKAYILFYVEHQAKAGSDKL :::::::::::::::::::::::::::::::::::::::: XP_016 RWFHFNDSTVTLTDEETVVKAKAYILFYVEHQAKAGSDKL 460 470 480 490 >>XP_016878252 (OMIM: 604728) PREDICTED: ubiquitin carbo (498 aa) initn: 3358 init1: 3358 opt: 3358 Z-score: 3545.3 bits: 665.6 E(85289): 9.8e-191 Smith-Waterman score: 3358; 99.8% identity (100.0% similar) in 491 aa overlap (30-520:8-498) 10 20 30 40 50 60 pF1KB4 MECPHLSSSVCIAPDSAKFPNGSPSSWCCSVCRSNKSPWVCLTCSSVHCGRYVNGHAKKH .:::::::::::::::::::::::::::::: XP_016 MQSPPHLAVCRSNKSPWVCLTCSSVHCGRYVNGHAKKH 10 20 30 70 80 90 100 110 120 pF1KB4 YEDAQVPLTNHKKSEKQDKVQHTVCMDCSSYSTYCYRCDDFVVNDTKLGLVQKVREHLQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YEDAQVPLTNHKKSEKQDKVQHTVCMDCSSYSTYCYRCDDFVVNDTKLGLVQKVREHLQN 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB4 LENSAFTADRHKKRKLLENSTLNSKLLKVNGSTTAICATGLRNLGNTCFMNAILQSLSNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LENSAFTADRHKKRKLLENSTLNSKLLKVNGSTTAICATGLRNLGNTCFMNAILQSLSNI 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB4 EQFCCYFKELPAVELRNGKTAGRRTYHTRSQGDNNVSLVEEFRKTLCALWQGSQTAFSPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EQFCCYFKELPAVELRNGKTAGRRTYHTRSQGDNNVSLVEEFRKTLCALWQGSQTAFSPE 160 170 180 190 200 210 250 260 270 280 290 300 pF1KB4 SLFYVVWKIMPNFRGYQQQDAHEFMRYLLDHLHLELQGGFNGVSRSAILQENSTLSASNK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SLFYVVWKIMPNFRGYQQQDAHEFMRYLLDHLHLELQGGFNGVSRSAILQENSTLSASNK 220 230 240 250 260 270 310 320 330 340 350 360 pF1KB4 CCINGASTVVTAIFGGILQNEVNCLICGTESRKFDPFLDLSLDIPSQFRSKRSKNQENGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CCINGASTVVTAIFGGILQNEVNCLICGTESRKFDPFLDLSLDIPSQFRSKRSKNQENGP 280 290 300 310 320 330 370 380 390 400 410 420 pF1KB4 VCSLRDCLRSFTDLEELDETELYMCHKCKKKQKSTKKFWIQKLPKVLCLHLKRFHWTAYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VCSLRDCLRSFTDLEELDETELYMCHKCKKKQKSTKKFWIQKLPKVLCLHLKRFHWTAYL 340 350 360 370 380 390 430 440 450 460 470 480 pF1KB4 RNKVDTYVEFPLRGLDMKCYLLEPENSGPESCLYDLAAVVVHHGSGVGSGHYTAYATHEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RNKVDTYVEFPLRGLDMKCYLLEPENSGPESCLYDLAAVVVHHGSGVGSGHYTAYATHEG 400 410 420 430 440 450 490 500 510 520 pF1KB4 RWFHFNDSTVTLTDEETVVKAKAYILFYVEHQAKAGSDKL :::::::::::::::::::::::::::::::::::::::: XP_016 RWFHFNDSTVTLTDEETVVKAKAYILFYVEHQAKAGSDKL 460 470 480 490 >>XP_016878254 (OMIM: 604728) PREDICTED: ubiquitin carbo (498 aa) initn: 3358 init1: 3358 opt: 3358 Z-score: 3545.3 bits: 665.6 E(85289): 9.8e-191 Smith-Waterman score: 3358; 99.8% identity (100.0% similar) in 491 aa overlap (30-520:8-498) 10 20 30 40 50 60 pF1KB4 MECPHLSSSVCIAPDSAKFPNGSPSSWCCSVCRSNKSPWVCLTCSSVHCGRYVNGHAKKH .:::::::::::::::::::::::::::::: XP_016 MQSPPHLAVCRSNKSPWVCLTCSSVHCGRYVNGHAKKH 10 20 30 70 80 90 100 110 120 pF1KB4 YEDAQVPLTNHKKSEKQDKVQHTVCMDCSSYSTYCYRCDDFVVNDTKLGLVQKVREHLQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YEDAQVPLTNHKKSEKQDKVQHTVCMDCSSYSTYCYRCDDFVVNDTKLGLVQKVREHLQN 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB4 LENSAFTADRHKKRKLLENSTLNSKLLKVNGSTTAICATGLRNLGNTCFMNAILQSLSNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LENSAFTADRHKKRKLLENSTLNSKLLKVNGSTTAICATGLRNLGNTCFMNAILQSLSNI 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB4 EQFCCYFKELPAVELRNGKTAGRRTYHTRSQGDNNVSLVEEFRKTLCALWQGSQTAFSPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EQFCCYFKELPAVELRNGKTAGRRTYHTRSQGDNNVSLVEEFRKTLCALWQGSQTAFSPE 160 170 180 190 200 210 250 260 270 280 290 300 pF1KB4 SLFYVVWKIMPNFRGYQQQDAHEFMRYLLDHLHLELQGGFNGVSRSAILQENSTLSASNK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SLFYVVWKIMPNFRGYQQQDAHEFMRYLLDHLHLELQGGFNGVSRSAILQENSTLSASNK 220 230 240 250 260 270 310 320 330 340 350 360 pF1KB4 CCINGASTVVTAIFGGILQNEVNCLICGTESRKFDPFLDLSLDIPSQFRSKRSKNQENGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CCINGASTVVTAIFGGILQNEVNCLICGTESRKFDPFLDLSLDIPSQFRSKRSKNQENGP 280 290 300 310 320 330 370 380 390 400 410 420 pF1KB4 VCSLRDCLRSFTDLEELDETELYMCHKCKKKQKSTKKFWIQKLPKVLCLHLKRFHWTAYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VCSLRDCLRSFTDLEELDETELYMCHKCKKKQKSTKKFWIQKLPKVLCLHLKRFHWTAYL 340 350 360 370 380 390 430 440 450 460 470 480 pF1KB4 RNKVDTYVEFPLRGLDMKCYLLEPENSGPESCLYDLAAVVVHHGSGVGSGHYTAYATHEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RNKVDTYVEFPLRGLDMKCYLLEPENSGPESCLYDLAAVVVHHGSGVGSGHYTAYATHEG 400 410 420 430 440 450 490 500 510 520 pF1KB4 RWFHFNDSTVTLTDEETVVKAKAYILFYVEHQAKAGSDKL :::::::::::::::::::::::::::::::::::::::: XP_016 RWFHFNDSTVTLTDEETVVKAKAYILFYVEHQAKAGSDKL 460 470 480 490 >>XP_016878256 (OMIM: 604728) PREDICTED: ubiquitin carbo (435 aa) initn: 2954 init1: 2954 opt: 2954 Z-score: 3120.3 bits: 586.7 E(85289): 4.6e-167 Smith-Waterman score: 2954; 100.0% identity (100.0% similar) in 435 aa overlap (86-520:1-435) 60 70 80 90 100 110 pF1KB4 HAKKHYEDAQVPLTNHKKSEKQDKVQHTVCMDCSSYSTYCYRCDDFVVNDTKLGLVQKVR :::::::::::::::::::::::::::::: XP_016 MDCSSYSTYCYRCDDFVVNDTKLGLVQKVR 10 20 30 120 130 140 150 160 170 pF1KB4 EHLQNLENSAFTADRHKKRKLLENSTLNSKLLKVNGSTTAICATGLRNLGNTCFMNAILQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EHLQNLENSAFTADRHKKRKLLENSTLNSKLLKVNGSTTAICATGLRNLGNTCFMNAILQ 40 50 60 70 80 90 180 190 200 210 220 230 pF1KB4 SLSNIEQFCCYFKELPAVELRNGKTAGRRTYHTRSQGDNNVSLVEEFRKTLCALWQGSQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SLSNIEQFCCYFKELPAVELRNGKTAGRRTYHTRSQGDNNVSLVEEFRKTLCALWQGSQT 100 110 120 130 140 150 240 250 260 270 280 290 pF1KB4 AFSPESLFYVVWKIMPNFRGYQQQDAHEFMRYLLDHLHLELQGGFNGVSRSAILQENSTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AFSPESLFYVVWKIMPNFRGYQQQDAHEFMRYLLDHLHLELQGGFNGVSRSAILQENSTL 160 170 180 190 200 210 300 310 320 330 340 350 pF1KB4 SASNKCCINGASTVVTAIFGGILQNEVNCLICGTESRKFDPFLDLSLDIPSQFRSKRSKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SASNKCCINGASTVVTAIFGGILQNEVNCLICGTESRKFDPFLDLSLDIPSQFRSKRSKN 220 230 240 250 260 270 360 370 380 390 400 410 pF1KB4 QENGPVCSLRDCLRSFTDLEELDETELYMCHKCKKKQKSTKKFWIQKLPKVLCLHLKRFH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QENGPVCSLRDCLRSFTDLEELDETELYMCHKCKKKQKSTKKFWIQKLPKVLCLHLKRFH 280 290 300 310 320 330 420 430 440 450 460 470 pF1KB4 WTAYLRNKVDTYVEFPLRGLDMKCYLLEPENSGPESCLYDLAAVVVHHGSGVGSGHYTAY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WTAYLRNKVDTYVEFPLRGLDMKCYLLEPENSGPESCLYDLAAVVVHHGSGVGSGHYTAY 340 350 360 370 380 390 480 490 500 510 520 pF1KB4 ATHEGRWFHFNDSTVTLTDEETVVKAKAYILFYVEHQAKAGSDKL ::::::::::::::::::::::::::::::::::::::::::::: XP_016 ATHEGRWFHFNDSTVTLTDEETVVKAKAYILFYVEHQAKAGSDKL 400 410 420 430 >>XP_016878255 (OMIM: 604728) PREDICTED: ubiquitin carbo (435 aa) initn: 2954 init1: 2954 opt: 2954 Z-score: 3120.3 bits: 586.7 E(85289): 4.6e-167 Smith-Waterman score: 2954; 100.0% identity (100.0% similar) in 435 aa overlap (86-520:1-435) 60 70 80 90 100 110 pF1KB4 HAKKHYEDAQVPLTNHKKSEKQDKVQHTVCMDCSSYSTYCYRCDDFVVNDTKLGLVQKVR :::::::::::::::::::::::::::::: XP_016 MDCSSYSTYCYRCDDFVVNDTKLGLVQKVR 10 20 30 120 130 140 150 160 170 pF1KB4 EHLQNLENSAFTADRHKKRKLLENSTLNSKLLKVNGSTTAICATGLRNLGNTCFMNAILQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EHLQNLENSAFTADRHKKRKLLENSTLNSKLLKVNGSTTAICATGLRNLGNTCFMNAILQ 40 50 60 70 80 90 180 190 200 210 220 230 pF1KB4 SLSNIEQFCCYFKELPAVELRNGKTAGRRTYHTRSQGDNNVSLVEEFRKTLCALWQGSQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SLSNIEQFCCYFKELPAVELRNGKTAGRRTYHTRSQGDNNVSLVEEFRKTLCALWQGSQT 100 110 120 130 140 150 240 250 260 270 280 290 pF1KB4 AFSPESLFYVVWKIMPNFRGYQQQDAHEFMRYLLDHLHLELQGGFNGVSRSAILQENSTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AFSPESLFYVVWKIMPNFRGYQQQDAHEFMRYLLDHLHLELQGGFNGVSRSAILQENSTL 160 170 180 190 200 210 300 310 320 330 340 350 pF1KB4 SASNKCCINGASTVVTAIFGGILQNEVNCLICGTESRKFDPFLDLSLDIPSQFRSKRSKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SASNKCCINGASTVVTAIFGGILQNEVNCLICGTESRKFDPFLDLSLDIPSQFRSKRSKN 220 230 240 250 260 270 360 370 380 390 400 410 pF1KB4 QENGPVCSLRDCLRSFTDLEELDETELYMCHKCKKKQKSTKKFWIQKLPKVLCLHLKRFH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QENGPVCSLRDCLRSFTDLEELDETELYMCHKCKKKQKSTKKFWIQKLPKVLCLHLKRFH 280 290 300 310 320 330 420 430 440 450 460 470 pF1KB4 WTAYLRNKVDTYVEFPLRGLDMKCYLLEPENSGPESCLYDLAAVVVHHGSGVGSGHYTAY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WTAYLRNKVDTYVEFPLRGLDMKCYLLEPENSGPESCLYDLAAVVVHHGSGVGSGHYTAY 340 350 360 370 380 390 480 490 500 510 520 pF1KB4 ATHEGRWFHFNDSTVTLTDEETVVKAKAYILFYVEHQAKAGSDKL ::::::::::::::::::::::::::::::::::::::::::::: XP_016 ATHEGRWFHFNDSTVTLTDEETVVKAKAYILFYVEHQAKAGSDKL 400 410 420 430 >>NP_001243631 (OMIM: 604728) ubiquitin carboxyl-termina (476 aa) initn: 2913 init1: 2913 opt: 2913 Z-score: 3076.5 bits: 578.8 E(85289): 1.3e-164 Smith-Waterman score: 3170; 91.3% identity (91.3% similar) in 520 aa overlap (1-520:1-476) 10 20 30 40 50 60 pF1KB4 MECPHLSSSVCIAPDSAKFPNGSPSSWCCSVCRSNKSPWVCLTCSSVHCGRYVNGHAKKH :::::::::::::::::::::::::::::::::::::::::::::::::: : NP_001 MECPHLSSSVCIAPDSAKFPNGSPSSWCCSVCRSNKSPWVCLTCSSVHCGSY-------- 10 20 30 40 50 70 80 90 100 110 120 pF1KB4 YEDAQVPLTNHKKSEKQDKVQHTVCMDCSSYSTYCYRCDDFVVNDTKLGLVQKVREHLQN :::::::::::::::::::::::: NP_001 ------------------------------------RCDDFVVNDTKLGLVQKVREHLQN 60 70 130 140 150 160 170 180 pF1KB4 LENSAFTADRHKKRKLLENSTLNSKLLKVNGSTTAICATGLRNLGNTCFMNAILQSLSNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LENSAFTADRHKKRKLLENSTLNSKLLKVNGSTTAICATGLRNLGNTCFMNAILQSLSNI 80 90 100 110 120 130 190 200 210 220 230 240 pF1KB4 EQFCCYFKELPAVELRNGKTAGRRTYHTRSQGDNNVSLVEEFRKTLCALWQGSQTAFSPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EQFCCYFKELPAVELRNGKTAGRRTYHTRSQGDNNVSLVEEFRKTLCALWQGSQTAFSPE 140 150 160 170 180 190 250 260 270 280 290 300 pF1KB4 SLFYVVWKIMPNFRGYQQQDAHEFMRYLLDHLHLELQGGFNGVSRSAILQENSTLSASNK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SLFYVVWKIMPNFRGYQQQDAHEFMRYLLDHLHLELQGGFNGVSRSAILQENSTLSASNK 200 210 220 230 240 250 310 320 330 340 350 360 pF1KB4 CCINGASTVVTAIFGGILQNEVNCLICGTESRKFDPFLDLSLDIPSQFRSKRSKNQENGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CCINGASTVVTAIFGGILQNEVNCLICGTESRKFDPFLDLSLDIPSQFRSKRSKNQENGP 260 270 280 290 300 310 370 380 390 400 410 420 pF1KB4 VCSLRDCLRSFTDLEELDETELYMCHKCKKKQKSTKKFWIQKLPKVLCLHLKRFHWTAYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VCSLRDCLRSFTDLEELDETELYMCHKCKKKQKSTKKFWIQKLPKVLCLHLKRFHWTAYL 320 330 340 350 360 370 430 440 450 460 470 480 pF1KB4 RNKVDTYVEFPLRGLDMKCYLLEPENSGPESCLYDLAAVVVHHGSGVGSGHYTAYATHEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RNKVDTYVEFPLRGLDMKCYLLEPENSGPESCLYDLAAVVVHHGSGVGSGHYTAYATHEG 380 390 400 410 420 430 490 500 510 520 pF1KB4 RWFHFNDSTVTLTDEETVVKAKAYILFYVEHQAKAGSDKL :::::::::::::::::::::::::::::::::::::::: NP_001 RWFHFNDSTVTLTDEETVVKAKAYILFYVEHQAKAGSDKL 440 450 460 470 >>XP_016878257 (OMIM: 604728) PREDICTED: ubiquitin carbo (351 aa) initn: 2397 init1: 2397 opt: 2397 Z-score: 2534.4 bits: 478.0 E(85289): 2e-134 Smith-Waterman score: 2397; 100.0% identity (100.0% similar) in 351 aa overlap (170-520:1-351) 140 150 160 170 180 190 pF1KB4 STLNSKLLKVNGSTTAICATGLRNLGNTCFMNAILQSLSNIEQFCCYFKELPAVELRNGK :::::::::::::::::::::::::::::: XP_016 MNAILQSLSNIEQFCCYFKELPAVELRNGK 10 20 30 200 210 220 230 240 250 pF1KB4 TAGRRTYHTRSQGDNNVSLVEEFRKTLCALWQGSQTAFSPESLFYVVWKIMPNFRGYQQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TAGRRTYHTRSQGDNNVSLVEEFRKTLCALWQGSQTAFSPESLFYVVWKIMPNFRGYQQQ 40 50 60 70 80 90 260 270 280 290 300 310 pF1KB4 DAHEFMRYLLDHLHLELQGGFNGVSRSAILQENSTLSASNKCCINGASTVVTAIFGGILQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DAHEFMRYLLDHLHLELQGGFNGVSRSAILQENSTLSASNKCCINGASTVVTAIFGGILQ 100 110 120 130 140 150 320 330 340 350 360 370 pF1KB4 NEVNCLICGTESRKFDPFLDLSLDIPSQFRSKRSKNQENGPVCSLRDCLRSFTDLEELDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NEVNCLICGTESRKFDPFLDLSLDIPSQFRSKRSKNQENGPVCSLRDCLRSFTDLEELDE 160 170 180 190 200 210 380 390 400 410 420 430 pF1KB4 TELYMCHKCKKKQKSTKKFWIQKLPKVLCLHLKRFHWTAYLRNKVDTYVEFPLRGLDMKC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TELYMCHKCKKKQKSTKKFWIQKLPKVLCLHLKRFHWTAYLRNKVDTYVEFPLRGLDMKC 220 230 240 250 260 270 440 450 460 470 480 490 pF1KB4 YLLEPENSGPESCLYDLAAVVVHHGSGVGSGHYTAYATHEGRWFHFNDSTVTLTDEETVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YLLEPENSGPESCLYDLAAVVVHHGSGVGSGHYTAYATHEGRWFHFNDSTVTLTDEETVV 280 290 300 310 320 330 500 510 520 pF1KB4 KAKAYILFYVEHQAKAGSDKL ::::::::::::::::::::: XP_016 KAKAYILFYVEHQAKAGSDKL 340 350 >>XP_016875500 (OMIM: 610993) PREDICTED: ubiquitin carbo (712 aa) initn: 721 init1: 191 opt: 602 Z-score: 638.0 bits: 128.1 E(85289): 8.5e-29 Smith-Waterman score: 710; 32.2% identity (58.5% similar) in 482 aa overlap (109-520:218-687) 80 90 100 110 120 130 pF1KB4 KVQHTVCMDCSSYSTYCYRCDDFVVNDTKLGLVQKVREHLQNLENSAFTADRHKKRKLLE ::.:.. .. ... : : : :.: XP_016 REVKKRRQELEYQVKAELESMPPRKSLRLQGLAQSTIIEIVSVQVPAQTPASPAKDKVLS 190 200 210 220 230 240 140 150 160 170 180 pF1KB4 NSTLNSKLLKVNGSTT------AICATGLRNLGNTCFMNAILQSLSNIEQF-CCYFK--- .: : ::. :.. . .::::::::::.::..:: ::.. : :..: XP_016 TSE-NEISQKVSDSSVKRRPIVTPGVTGLRNLGNTCYMNSVLQVLSHLLIFRQCFLKLDL 250 260 270 280 290 300 190 200 pF1KB4 ---------------ELPAVE----------------------------LRNGKTAGRRT . : : : .: . ::. XP_016 NQWLAMTASEKTRSCKHPPVTDTVVYQMNECQEKDTGFVCSRQSSLSSGLSGGASKGRKM 310 320 330 340 350 360 210 220 230 240 250 260 pF1KB4 --YHTRSQGDNNVSLVEEFRKTLCALWQGSQTAFSPESLFYVVWKIMPNFRGYQQQDAHE . . .. .:: .:.. . ..:.:. . :: .... ::...: :::: ::::.: XP_016 ELIQPKEPTSQYISLCHELHTLFQVMWSGKWALVSPFAMLHSVWRLIPAFRGYAQQDAQE 370 380 390 400 410 420 270 280 290 300 310 320 pF1KB4 FMRYLLDHLHLELQGGFNGVSRSAILQENSTLSASNKCCINGASTVVTAIFGGILQNEVN :. :::... ::. .:.: :. . .:.. :. . .::. :: : : ..:. XP_016 FLCELLDKIQRELET--TGTSLPAL------IPTSQRKLIKQVLNVVNNIFHGQLLSQVT 430 440 450 460 470 330 340 350 360 370 380 pF1KB4 CLICGTESRKFDPFLDLSLDIPSQFRSKRSKNQENGPVCSLRDCLRSFTDLEELDETELY :: : ..: ..:: ::::..: ... . .:. . : : . . : .::. : : : ..: XP_016 CLACDNKSNTIEPFWDLSLEFPERYQCS-GKDIASQP-CLVTEMLAKFTETEAL-EGKIY 480 490 500 510 520 530 390 400 410 420 430 pF1KB4 MCHKCKKKQK-----------STKKFWIQKLPKVLCLHLKRFHWTAYL-RNKVDTYVEFP .: .:..:.. . :.. : .::.:: ::::::.:.. :.:. ..: : XP_016 VCDQCNSKRRRFSSKPVVLTEAQKQLMICHLPQVLRLHLKRFRWSGRNNREKIGVHVGFE 540 550 560 570 580 590 440 450 460 470 480 pF1KB4 -LRGLDMKCYLLEPENSGPESCLYDLAAVVVHHGSGVGSGHYTAYA--THEGRWFHFNDS . ... : .. :: .:::.:::.:::.: :::::::: .. : : : ::: XP_016 EILNMEPYCCRETLKSLRPECFIYDLSAVVMHHGKGFGSGHYTAYCYNSEGGFWVHCNDS 600 610 620 630 640 650 490 500 510 520 pF1KB4 TVTLTDEETVVKAKAYILFYVEHQAKAGSDKL ... . : ::.::::::... .. : .:: XP_016 KLSMCTMDEVCKAQAYILFYTQRVTENGHSKLLPPELLLGSQHPNEDADTSSNEILS 660 670 680 690 700 710 >-- initn: 240 init1: 121 opt: 255 Z-score: 272.2 bits: 60.5 E(85289): 2e-08 Smith-Waterman score: 255; 26.3% identity (60.5% similar) in 152 aa overlap (3-154:7-138) 10 20 30 40 50 pF1KB4 MECPHLSSSVCIAPDSAKFPNGSPSSWCCSVCRSNKSPWVCLTCSSVHCGRYVNGH : :... . .: : ... .:..: : : ...: :.::.:: : ::::.. : XP_016 MLAMDTCKHVGQ-LQLAQDHSSL---NPQKWHCVDCNTTESIWACLSCSHVACGRYIEEH 10 20 30 40 50 60 70 80 90 100 110 pF1KB4 AKKHYEDAQVPLTNHKKSEKQDKVQHTVCMDCSSYSTYCYRCDDFVVNDTKLGLVQKVRE : ::..... : : .. . . ..:: :::.:.::. : .. .:. XP_016 ALKHFQESS----------------HPVALEVNEMYVFCYLCDDYVLNDNTTGDLKLLRR 60 70 80 90 100 120 130 140 150 160 170 pF1KB4 HLQNLENSAFTADRHKKRKLLENSTLNSKLLKVNGSTTAICATGLRNLGNTCFMNAILQS :. .... . .. : : .: ... . .:. . XP_016 TLSAIKSQNYHCTTRSGRFLRSMGTGDDSYFLHDGAQSLLQSEDQLYTALWHRRRILMGK 110 120 130 140 150 160 180 190 200 210 220 230 pF1KB4 LSNIEQFCCYFKELPAVELRNGKTAGRRTYHTRSQGDNNVSLVEEFRKTLCALWQGSQTA XP_016 IFRTWFEQSPIGRKKQEEPFQEKIVVKREVKKRRQELEYQVKAELESMPPRKSLRLQGLA 170 180 190 200 210 220 >>NP_001035862 (OMIM: 610993) ubiquitin carboxyl-termina (712 aa) initn: 721 init1: 191 opt: 602 Z-score: 638.0 bits: 128.1 E(85289): 8.5e-29 Smith-Waterman score: 710; 32.2% identity (58.5% similar) in 482 aa overlap (109-520:218-687) 80 90 100 110 120 130 pF1KB4 KVQHTVCMDCSSYSTYCYRCDDFVVNDTKLGLVQKVREHLQNLENSAFTADRHKKRKLLE ::.:.. .. ... : : : :.: NP_001 REVKKRRQELEYQVKAELESMPPRKSLRLQGLAQSTIIEIVSVQVPAQTPASPAKDKVLS 190 200 210 220 230 240 140 150 160 170 180 pF1KB4 NSTLNSKLLKVNGSTT------AICATGLRNLGNTCFMNAILQSLSNIEQF-CCYFK--- .: : ::. :.. . .::::::::::.::..:: ::.. : :..: NP_001 TSE-NEISQKVSDSSVKRRPIVTPGVTGLRNLGNTCYMNSVLQVLSHLLIFRQCFLKLDL 250 260 270 280 290 300 190 200 pF1KB4 ---------------ELPAVE----------------------------LRNGKTAGRRT . : : : .: . ::. NP_001 NQWLAMTASEKTRSCKHPPVTDTVVYQMNECQEKDTGFVCSRQSSLSSGLSGGASKGRKM 310 320 330 340 350 360 210 220 230 240 250 260 pF1KB4 --YHTRSQGDNNVSLVEEFRKTLCALWQGSQTAFSPESLFYVVWKIMPNFRGYQQQDAHE . . .. .:: .:.. . ..:.:. . :: .... ::...: :::: ::::.: NP_001 ELIQPKEPTSQYISLCHELHTLFQVMWSGKWALVSPFAMLHSVWRLIPAFRGYAQQDAQE 370 380 390 400 410 420 270 280 290 300 310 320 pF1KB4 FMRYLLDHLHLELQGGFNGVSRSAILQENSTLSASNKCCINGASTVVTAIFGGILQNEVN :. :::... ::. .:.: :. . .:.. :. . .::. :: : : ..:. NP_001 FLCELLDKIQRELET--TGTSLPAL------IPTSQRKLIKQVLNVVNNIFHGQLLSQVT 430 440 450 460 470 330 340 350 360 370 380 pF1KB4 CLICGTESRKFDPFLDLSLDIPSQFRSKRSKNQENGPVCSLRDCLRSFTDLEELDETELY :: : ..: ..:: ::::..: ... . .:. . : : . . : .::. : : : ..: NP_001 CLACDNKSNTIEPFWDLSLEFPERYQCS-GKDIASQP-CLVTEMLAKFTETEAL-EGKIY 480 490 500 510 520 530 390 400 410 420 430 pF1KB4 MCHKCKKKQK-----------STKKFWIQKLPKVLCLHLKRFHWTAYL-RNKVDTYVEFP .: .:..:.. . :.. : .::.:: ::::::.:.. :.:. ..: : NP_001 VCDQCNSKRRRFSSKPVVLTEAQKQLMICHLPQVLRLHLKRFRWSGRNNREKIGVHVGFE 540 550 560 570 580 590 440 450 460 470 480 pF1KB4 -LRGLDMKCYLLEPENSGPESCLYDLAAVVVHHGSGVGSGHYTAYA--THEGRWFHFNDS . ... : .. :: .:::.:::.:::.: :::::::: .. : : : ::: NP_001 EILNMEPYCCRETLKSLRPECFIYDLSAVVMHHGKGFGSGHYTAYCYNSEGGFWVHCNDS 600 610 620 630 640 650 490 500 510 520 pF1KB4 TVTLTDEETVVKAKAYILFYVEHQAKAGSDKL ... . : ::.::::::... .. : .:: NP_001 KLSMCTMDEVCKAQAYILFYTQRVTENGHSKLLPPELLLGSQHPNEDADTSSNEILS 660 670 680 690 700 710 >-- initn: 240 init1: 121 opt: 255 Z-score: 272.2 bits: 60.5 E(85289): 2e-08 Smith-Waterman score: 255; 26.3% identity (60.5% similar) in 152 aa overlap (3-154:7-138) 10 20 30 40 50 pF1KB4 MECPHLSSSVCIAPDSAKFPNGSPSSWCCSVCRSNKSPWVCLTCSSVHCGRYVNGH : :... . .: : ... .:..: : : ...: :.::.:: : ::::.. : NP_001 MLAMDTCKHVGQ-LQLAQDHSSL---NPQKWHCVDCNTTESIWACLSCSHVACGRYIEEH 10 20 30 40 50 60 70 80 90 100 110 pF1KB4 AKKHYEDAQVPLTNHKKSEKQDKVQHTVCMDCSSYSTYCYRCDDFVVNDTKLGLVQKVRE : ::..... : : .. . . ..:: :::.:.::. : .. .:. NP_001 ALKHFQESS----------------HPVALEVNEMYVFCYLCDDYVLNDNTTGDLKLLRR 60 70 80 90 100 120 130 140 150 160 170 pF1KB4 HLQNLENSAFTADRHKKRKLLENSTLNSKLLKVNGSTTAICATGLRNLGNTCFMNAILQS :. .... . .. : : .: ... . .:. . NP_001 TLSAIKSQNYHCTTRSGRFLRSMGTGDDSYFLHDGAQSLLQSEDQLYTALWHRRRILMGK 110 120 130 140 150 160 180 190 200 210 220 230 pF1KB4 LSNIEQFCCYFKELPAVELRNGKTAGRRTYHTRSQGDNNVSLVEEFRKTLCALWQGSQTA NP_001 IFRTWFEQSPIGRKKQEEPFQEKIVVKREVKKRRQELEYQVKAELESMPPRKSLRLQGLA 170 180 190 200 210 220 520 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 14:55:58 2016 done: Thu Nov 3 14:56:00 2016 Total Scan time: 9.120 Total Display time: 0.100 Function used was FASTA [36.3.4 Apr, 2011]