FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB4421, 525 aa 1>>>pF1KB4421 525 - 525 aa - 525 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 9.2424+/-0.000562; mu= 0.2540+/- 0.034 mean_var=584.7720+/-133.886, 0's: 0 Z-trim(116.7): 1875 B-trim: 0 in 0/54 Lambda= 0.053037 statistics sampled from 25578 (28117) to 25578 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.681), E-opt: 0.2 (0.33), width: 16 Scan time: 10.040 The best scores are: opt bits E(85289) NP_003152 (OMIM: 608938) ribosomal protein S6 kina ( 525) 3553 287.9 5e-77 NP_001258989 (OMIM: 608938) ribosomal protein S6 k ( 502) 3384 275.0 3.8e-73 NP_001258973 (OMIM: 608938) ribosomal protein S6 k ( 472) 3185 259.7 1.4e-68 NP_001258972 (OMIM: 608938) ribosomal protein S6 k ( 451) 3013 246.5 1.3e-64 NP_001258971 (OMIM: 608938) ribosomal protein S6 k ( 502) 2689 221.8 3.9e-57 XP_011523404 (OMIM: 608938) PREDICTED: ribosomal p ( 391) 2537 210.0 1.1e-53 XP_011523403 (OMIM: 608938) PREDICTED: ribosomal p ( 489) 2535 210.0 1.4e-53 NP_003943 (OMIM: 608939) ribosomal protein S6 kina ( 482) 2219 185.8 2.6e-46 XP_016880421 (OMIM: 608938) PREDICTED: ribosomal p ( 322) 2196 183.7 7.1e-46 XP_016880419 (OMIM: 608938) PREDICTED: ribosomal p ( 322) 2196 183.7 7.1e-46 XP_011523405 (OMIM: 608938) PREDICTED: ribosomal p ( 322) 2196 183.7 7.1e-46 XP_016880420 (OMIM: 608938) PREDICTED: ribosomal p ( 322) 2196 183.7 7.1e-46 XP_016880418 (OMIM: 608938) PREDICTED: ribosomal p ( 436) 2167 181.7 3.8e-45 XP_005274221 (OMIM: 608939) PREDICTED: ribosomal p ( 385) 1904 161.5 4.1e-39 XP_016873597 (OMIM: 608939) PREDICTED: ribosomal p ( 282) 1320 116.6 1e-25 XP_006718718 (OMIM: 608939) PREDICTED: ribosomal p ( 282) 1320 116.6 1e-25 XP_005274222 (OMIM: 608939) PREDICTED: ribosomal p ( 282) 1320 116.6 1e-25 XP_006718720 (OMIM: 608939) PREDICTED: ribosomal p ( 282) 1320 116.6 1e-25 XP_006718719 (OMIM: 608939) PREDICTED: ribosomal p ( 282) 1320 116.6 1e-25 NP_001305865 (OMIM: 601685) ribosomal protein S6 k ( 758) 1273 113.7 2e-24 XP_005274630 (OMIM: 300075,300844,303600) PREDICTE ( 739) 1266 113.2 2.8e-24 NP_004577 (OMIM: 300075,300844,303600) ribosomal p ( 740) 1266 113.2 2.8e-24 NP_001006666 (OMIM: 601684) ribosomal protein S6 k ( 744) 1264 113.0 3.1e-24 NP_002944 (OMIM: 601684) ribosomal protein S6 kina ( 735) 1257 112.5 4.5e-24 NP_001317370 (OMIM: 601684) ribosomal protein S6 k ( 719) 1255 112.3 5e-24 NP_066958 (OMIM: 601685) ribosomal protein S6 kina ( 733) 1255 112.3 5e-24 NP_001006933 (OMIM: 601685) ribosomal protein S6 k ( 741) 1255 112.3 5.1e-24 XP_006715612 (OMIM: 601685) PREDICTED: ribosomal p ( 761) 1255 112.4 5.1e-24 XP_016885208 (OMIM: 300075,300844,303600) PREDICTE ( 711) 1254 112.2 5.2e-24 XP_006724570 (OMIM: 300075,300844,303600) PREDICTE ( 711) 1254 112.2 5.2e-24 XP_011543865 (OMIM: 300075,300844,303600) PREDICTE ( 712) 1254 112.2 5.2e-24 XP_016885204 (OMIM: 300075,300844,303600) PREDICTE ( 712) 1254 112.2 5.2e-24 XP_016885206 (OMIM: 300075,300844,303600) PREDICTE ( 712) 1254 112.2 5.2e-24 XP_016885203 (OMIM: 300075,300844,303600) PREDICTE ( 712) 1254 112.2 5.2e-24 XP_016885205 (OMIM: 300075,300844,303600) PREDICTE ( 712) 1254 112.2 5.2e-24 XP_016885202 (OMIM: 300075,300844,303600) PREDICTE ( 712) 1254 112.2 5.2e-24 XP_005274634 (OMIM: 300075,300844,303600) PREDICTE ( 710) 1251 112.0 6.1e-24 XP_016885207 (OMIM: 300075,300844,303600) PREDICTE ( 711) 1251 112.0 6.1e-24 XP_011543858 (OMIM: 300075,300844,303600) PREDICTE ( 745) 1244 111.5 9.1e-24 XP_011543857 (OMIM: 300075,300844,303600) PREDICTE ( 746) 1244 111.5 9.1e-24 XP_011543863 (OMIM: 300075,300844,303600) PREDICTE ( 718) 1232 110.6 1.7e-23 XP_011543861 (OMIM: 300075,300844,303600) PREDICTE ( 718) 1232 110.6 1.7e-23 XP_011543862 (OMIM: 300075,300844,303600) PREDICTE ( 718) 1232 110.6 1.7e-23 XP_011543859 (OMIM: 300075,300844,303600) PREDICTE ( 718) 1232 110.6 1.7e-23 XP_011543860 (OMIM: 300075,300844,303600) PREDICTE ( 718) 1232 110.6 1.7e-23 NP_055311 (OMIM: 300303) ribosomal protein S6 kina ( 745) 1232 110.6 1.7e-23 XP_011543864 (OMIM: 300075,300844,303600) PREDICTE ( 717) 1229 110.3 2e-23 NP_001317441 (OMIM: 300303) ribosomal protein S6 k ( 745) 1229 110.4 2e-23 XP_011529219 (OMIM: 300303) PREDICTED: ribosomal p ( 745) 1229 110.4 2e-23 XP_016884912 (OMIM: 300303) PREDICTED: ribosomal p ( 762) 1229 110.4 2e-23 >>NP_003152 (OMIM: 608938) ribosomal protein S6 kinase b (525 aa) initn: 3553 init1: 3553 opt: 3553 Z-score: 1503.9 bits: 287.9 E(85289): 5e-77 Smith-Waterman score: 3553; 100.0% identity (100.0% similar) in 525 aa overlap (1-525:1-525) 10 20 30 40 50 60 pF1KB4 MRRRRRRDGFYPAPDFRDREAEDMAGVFDIDLDQPEDAGSEDELEEGGQLNESMDHGGVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 MRRRRRRDGFYPAPDFRDREAEDMAGVFDIDLDQPEDAGSEDELEEGGQLNESMDHGGVG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 PYELGMEHCEKFEISETSVNRGPEKIRPECFELLRVLGKGGYGKVFQVRKVTGANTGKIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 PYELGMEHCEKFEISETSVNRGPEKIRPECFELLRVLGKGGYGKVFQVRKVTGANTGKIF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 AMKVLKKAMIVRNAKDTAHTKAERNILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 AMKVLKKAMIVRNAKDTAHTKAERNILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGEL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 FMQLEREGIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 FMQLEREGIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLC 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 KESIHDGTVTHTFCGTIEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 KESIHDGTVTHTFCGTIEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 TIDKILKCKLNLPPYLTQEARDLLKKLLKRNAASRLGAGPGDAGEVQAHPFFRHINWEEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 TIDKILKCKLNLPPYLTQEARDLLKKLLKRNAASRLGAGPGDAGEVQAHPFFRHINWEEL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB4 LARKVEPPFKPLLQSEEDVSQFDSKFTRQTPVDSPDDSTLSESANQVFLGFTYVAPSVLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 LARKVEPPFKPLLQSEEDVSQFDSKFTRQTPVDSPDDSTLSESANQVFLGFTYVAPSVLE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB4 SVKEKFSFEPKIRSPRRFIGSPRTPVSPVKFSPGDFWGRGASASTANPQTPVEYPMETSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 SVKEKFSFEPKIRSPRRFIGSPRTPVSPVKFSPGDFWGRGASASTANPQTPVEYPMETSG 430 440 450 460 470 480 490 500 510 520 pF1KB4 IEQMDVTMSGEASAPLPIRQPNSGPYKKQAFPMISKRPEHLRMNL ::::::::::::::::::::::::::::::::::::::::::::: NP_003 IEQMDVTMSGEASAPLPIRQPNSGPYKKQAFPMISKRPEHLRMNL 490 500 510 520 >>NP_001258989 (OMIM: 608938) ribosomal protein S6 kinas (502 aa) initn: 3384 init1: 3384 opt: 3384 Z-score: 1434.2 bits: 275.0 E(85289): 3.8e-73 Smith-Waterman score: 3384; 100.0% identity (100.0% similar) in 502 aa overlap (24-525:1-502) 10 20 30 40 50 60 pF1KB4 MRRRRRRDGFYPAPDFRDREAEDMAGVFDIDLDQPEDAGSEDELEEGGQLNESMDHGGVG ::::::::::::::::::::::::::::::::::::: NP_001 MAGVFDIDLDQPEDAGSEDELEEGGQLNESMDHGGVG 10 20 30 70 80 90 100 110 120 pF1KB4 PYELGMEHCEKFEISETSVNRGPEKIRPECFELLRVLGKGGYGKVFQVRKVTGANTGKIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PYELGMEHCEKFEISETSVNRGPEKIRPECFELLRVLGKGGYGKVFQVRKVTGANTGKIF 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB4 AMKVLKKAMIVRNAKDTAHTKAERNILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AMKVLKKAMIVRNAKDTAHTKAERNILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGEL 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB4 FMQLEREGIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FMQLEREGIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLC 160 170 180 190 200 210 250 260 270 280 290 300 pF1KB4 KESIHDGTVTHTFCGTIEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KESIHDGTVTHTFCGTIEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKK 220 230 240 250 260 270 310 320 330 340 350 360 pF1KB4 TIDKILKCKLNLPPYLTQEARDLLKKLLKRNAASRLGAGPGDAGEVQAHPFFRHINWEEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TIDKILKCKLNLPPYLTQEARDLLKKLLKRNAASRLGAGPGDAGEVQAHPFFRHINWEEL 280 290 300 310 320 330 370 380 390 400 410 420 pF1KB4 LARKVEPPFKPLLQSEEDVSQFDSKFTRQTPVDSPDDSTLSESANQVFLGFTYVAPSVLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LARKVEPPFKPLLQSEEDVSQFDSKFTRQTPVDSPDDSTLSESANQVFLGFTYVAPSVLE 340 350 360 370 380 390 430 440 450 460 470 480 pF1KB4 SVKEKFSFEPKIRSPRRFIGSPRTPVSPVKFSPGDFWGRGASASTANPQTPVEYPMETSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SVKEKFSFEPKIRSPRRFIGSPRTPVSPVKFSPGDFWGRGASASTANPQTPVEYPMETSG 400 410 420 430 440 450 490 500 510 520 pF1KB4 IEQMDVTMSGEASAPLPIRQPNSGPYKKQAFPMISKRPEHLRMNL ::::::::::::::::::::::::::::::::::::::::::::: NP_001 IEQMDVTMSGEASAPLPIRQPNSGPYKKQAFPMISKRPEHLRMNL 460 470 480 490 500 >>NP_001258973 (OMIM: 608938) ribosomal protein S6 kinas (472 aa) initn: 3185 init1: 3185 opt: 3185 Z-score: 1352.1 bits: 259.7 E(85289): 1.4e-68 Smith-Waterman score: 3185; 100.0% identity (100.0% similar) in 472 aa overlap (54-525:1-472) 30 40 50 60 70 80 pF1KB4 MAGVFDIDLDQPEDAGSEDELEEGGQLNESMDHGGVGPYELGMEHCEKFEISETSVNRGP :::::::::::::::::::::::::::::: NP_001 MDHGGVGPYELGMEHCEKFEISETSVNRGP 10 20 30 90 100 110 120 130 140 pF1KB4 EKIRPECFELLRVLGKGGYGKVFQVRKVTGANTGKIFAMKVLKKAMIVRNAKDTAHTKAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EKIRPECFELLRVLGKGGYGKVFQVRKVTGANTGKIFAMKVLKKAMIVRNAKDTAHTKAE 40 50 60 70 80 90 150 160 170 180 190 200 pF1KB4 RNILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLEREGIFMEDTACFYLAEIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RNILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLEREGIFMEDTACFYLAEIS 100 110 120 130 140 150 210 220 230 240 250 260 pF1KB4 MALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLCKESIHDGTVTHTFCGTIEYMAPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLCKESIHDGTVTHTFCGTIEYMAPE 160 170 180 190 200 210 270 280 290 300 310 320 pF1KB4 ILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCKLNLPPYLTQEARDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCKLNLPPYLTQEARDL 220 230 240 250 260 270 330 340 350 360 370 380 pF1KB4 LKKLLKRNAASRLGAGPGDAGEVQAHPFFRHINWEELLARKVEPPFKPLLQSEEDVSQFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LKKLLKRNAASRLGAGPGDAGEVQAHPFFRHINWEELLARKVEPPFKPLLQSEEDVSQFD 280 290 300 310 320 330 390 400 410 420 430 440 pF1KB4 SKFTRQTPVDSPDDSTLSESANQVFLGFTYVAPSVLESVKEKFSFEPKIRSPRRFIGSPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SKFTRQTPVDSPDDSTLSESANQVFLGFTYVAPSVLESVKEKFSFEPKIRSPRRFIGSPR 340 350 360 370 380 390 450 460 470 480 490 500 pF1KB4 TPVSPVKFSPGDFWGRGASASTANPQTPVEYPMETSGIEQMDVTMSGEASAPLPIRQPNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TPVSPVKFSPGDFWGRGASASTANPQTPVEYPMETSGIEQMDVTMSGEASAPLPIRQPNS 400 410 420 430 440 450 510 520 pF1KB4 GPYKKQAFPMISKRPEHLRMNL :::::::::::::::::::::: NP_001 GPYKKQAFPMISKRPEHLRMNL 460 470 >>NP_001258972 (OMIM: 608938) ribosomal protein S6 kinas (451 aa) initn: 3013 init1: 3013 opt: 3013 Z-score: 1281.2 bits: 246.5 E(85289): 1.3e-64 Smith-Waterman score: 3013; 100.0% identity (100.0% similar) in 447 aa overlap (1-447:1-447) 10 20 30 40 50 60 pF1KB4 MRRRRRRDGFYPAPDFRDREAEDMAGVFDIDLDQPEDAGSEDELEEGGQLNESMDHGGVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MRRRRRRDGFYPAPDFRDREAEDMAGVFDIDLDQPEDAGSEDELEEGGQLNESMDHGGVG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 PYELGMEHCEKFEISETSVNRGPEKIRPECFELLRVLGKGGYGKVFQVRKVTGANTGKIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PYELGMEHCEKFEISETSVNRGPEKIRPECFELLRVLGKGGYGKVFQVRKVTGANTGKIF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 AMKVLKKAMIVRNAKDTAHTKAERNILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AMKVLKKAMIVRNAKDTAHTKAERNILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGEL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 FMQLEREGIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FMQLEREGIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLC 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 KESIHDGTVTHTFCGTIEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KESIHDGTVTHTFCGTIEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 TIDKILKCKLNLPPYLTQEARDLLKKLLKRNAASRLGAGPGDAGEVQAHPFFRHINWEEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TIDKILKCKLNLPPYLTQEARDLLKKLLKRNAASRLGAGPGDAGEVQAHPFFRHINWEEL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB4 LARKVEPPFKPLLQSEEDVSQFDSKFTRQTPVDSPDDSTLSESANQVFLGFTYVAPSVLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LARKVEPPFKPLLQSEEDVSQFDSKFTRQTPVDSPDDSTLSESANQVFLGFTYVAPSVLE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB4 SVKEKFSFEPKIRSPRRFIGSPRTPVSPVKFSPGDFWGRGASASTANPQTPVEYPMETSG ::::::::::::::::::::::::::: NP_001 SVKEKFSFEPKIRSPRRFIGSPRTPVSTAMC 430 440 450 >>NP_001258971 (OMIM: 608938) ribosomal protein S6 kinas (502 aa) initn: 2689 init1: 2689 opt: 2689 Z-score: 1146.8 bits: 221.8 E(85289): 3.9e-57 Smith-Waterman score: 3357; 95.6% identity (95.6% similar) in 525 aa overlap (1-525:1-502) 10 20 30 40 50 60 pF1KB4 MRRRRRRDGFYPAPDFRDREAEDMAGVFDIDLDQPEDAGSEDELEEGGQLNESMDHGGVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MRRRRRRDGFYPAPDFRDREAEDMAGVFDIDLDQPEDAGSEDELEEGGQLNESMDHGGVG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 PYELGMEHCEKFEISETSVNRGPEKIRPECFELLRVLGKGGYGKVFQVRKVTGANTGKIF :::::::::::::::::::::::::::::::::::::::::::: NP_001 PYELGMEHCEKFEISETSVNRGPEKIRPECFELLRVLGKGGYGK---------------- 70 80 90 100 130 140 150 160 170 180 pF1KB4 AMKVLKKAMIVRNAKDTAHTKAERNILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGEL ::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 -------AMIVRNAKDTAHTKAERNILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGEL 110 120 130 140 150 190 200 210 220 230 240 pF1KB4 FMQLEREGIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FMQLEREGIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLC 160 170 180 190 200 210 250 260 270 280 290 300 pF1KB4 KESIHDGTVTHTFCGTIEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KESIHDGTVTHTFCGTIEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKK 220 230 240 250 260 270 310 320 330 340 350 360 pF1KB4 TIDKILKCKLNLPPYLTQEARDLLKKLLKRNAASRLGAGPGDAGEVQAHPFFRHINWEEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TIDKILKCKLNLPPYLTQEARDLLKKLLKRNAASRLGAGPGDAGEVQAHPFFRHINWEEL 280 290 300 310 320 330 370 380 390 400 410 420 pF1KB4 LARKVEPPFKPLLQSEEDVSQFDSKFTRQTPVDSPDDSTLSESANQVFLGFTYVAPSVLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LARKVEPPFKPLLQSEEDVSQFDSKFTRQTPVDSPDDSTLSESANQVFLGFTYVAPSVLE 340 350 360 370 380 390 430 440 450 460 470 480 pF1KB4 SVKEKFSFEPKIRSPRRFIGSPRTPVSPVKFSPGDFWGRGASASTANPQTPVEYPMETSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SVKEKFSFEPKIRSPRRFIGSPRTPVSPVKFSPGDFWGRGASASTANPQTPVEYPMETSG 400 410 420 430 440 450 490 500 510 520 pF1KB4 IEQMDVTMSGEASAPLPIRQPNSGPYKKQAFPMISKRPEHLRMNL ::::::::::::::::::::::::::::::::::::::::::::: NP_001 IEQMDVTMSGEASAPLPIRQPNSGPYKKQAFPMISKRPEHLRMNL 460 470 480 490 500 >>XP_011523404 (OMIM: 608938) PREDICTED: ribosomal prote (391 aa) initn: 2533 init1: 2533 opt: 2537 Z-score: 1084.9 bits: 210.0 E(85289): 1.1e-53 Smith-Waterman score: 2537; 98.7% identity (99.2% similar) in 379 aa overlap (1-379:1-379) 10 20 30 40 50 60 pF1KB4 MRRRRRRDGFYPAPDFRDREAEDMAGVFDIDLDQPEDAGSEDELEEGGQLNESMDHGGVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MRRRRRRDGFYPAPDFRDREAEDMAGVFDIDLDQPEDAGSEDELEEGGQLNESMDHGGVG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 PYELGMEHCEKFEISETSVNRGPEKIRPECFELLRVLGKGGYGKVFQVRKVTGANTGKIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PYELGMEHCEKFEISETSVNRGPEKIRPECFELLRVLGKGGYGKVFQVRKVTGANTGKIF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 AMKVLKKAMIVRNAKDTAHTKAERNILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AMKVLKKAMIVRNAKDTAHTKAERNILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGEL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 FMQLEREGIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FMQLEREGIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLC 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 KESIHDGTVTHTFCGTIEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KESIHDGTVTHTFCGTIEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 TIDKILKCKLNLPPYLTQEARDLLKKLLKRNAASRLGAGPGDAGEVQAHPFFRHINWEEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TIDKILKCKLNLPPYLTQEARDLLKKLLKRNAASRLGAGPGDAGEVQAHPFFRHINWEEL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB4 LARKVEPPFKPLLQSEEDVSQFDSKFTRQTPVDSPDDSTLSESANQVFLGFTYVAPSVLE ::::::::::::: . :. XP_011 LARKVEPPFKPLLVHHPDLCLHVHMVFYLSI 370 380 390 >>XP_011523403 (OMIM: 608938) PREDICTED: ribosomal prote (489 aa) initn: 2533 init1: 2533 opt: 2535 Z-score: 1083.2 bits: 210.0 E(85289): 1.4e-53 Smith-Waterman score: 3241; 93.1% identity (93.1% similar) in 525 aa overlap (1-525:1-489) 10 20 30 40 50 60 pF1KB4 MRRRRRRDGFYPAPDFRDREAEDMAGVFDIDLDQPEDAGSEDELEEGGQLNESMDHGGVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MRRRRRRDGFYPAPDFRDREAEDMAGVFDIDLDQPEDAGSEDELEEGGQLNESMDHGGVG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 PYELGMEHCEKFEISETSVNRGPEKIRPECFELLRVLGKGGYGKVFQVRKVTGANTGKIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PYELGMEHCEKFEISETSVNRGPEKIRPECFELLRVLGKGGYGKVFQVRKVTGANTGKIF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 AMKVLKKAMIVRNAKDTAHTKAERNILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AMKVLKKAMIVRNAKDTAHTKAERNILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGEL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 FMQLEREGIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FMQLEREGIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLC 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 KESIHDGTVTHTFCGTIEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KESIHDGTVTHTFCGTIEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 TIDKILKCKLNLPPYLTQEARDLLKKLLKRNAASRLGAGPGDAGEVQAHPFFRHINWEEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TIDKILKCKLNLPPYLTQEARDLLKKLLKRNAASRLGAGPGDAGEVQAHPFFRHINWEEL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB4 LARKVEPPFKPLLQSEEDVSQFDSKFTRQTPVDSPDDSTLSESANQVFLGFTYVAPSVLE ::::::::::::: ::::::::::: XP_011 LARKVEPPFKPLL------------------------------------GFTYVAPSVLE 370 380 430 440 450 460 470 480 pF1KB4 SVKEKFSFEPKIRSPRRFIGSPRTPVSPVKFSPGDFWGRGASASTANPQTPVEYPMETSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SVKEKFSFEPKIRSPRRFIGSPRTPVSPVKFSPGDFWGRGASASTANPQTPVEYPMETSG 390 400 410 420 430 440 490 500 510 520 pF1KB4 IEQMDVTMSGEASAPLPIRQPNSGPYKKQAFPMISKRPEHLRMNL ::::::::::::::::::::::::::::::::::::::::::::: XP_011 IEQMDVTMSGEASAPLPIRQPNSGPYKKQAFPMISKRPEHLRMNL 450 460 470 480 >>NP_003943 (OMIM: 608939) ribosomal protein S6 kinase b (482 aa) initn: 2285 init1: 2167 opt: 2219 Z-score: 952.6 bits: 185.8 E(85289): 2.6e-46 Smith-Waterman score: 2244; 70.4% identity (85.3% similar) in 490 aa overlap (24-509:1-474) 10 20 30 40 50 pF1KB4 MRRRRRRDGFYPAPDFRDREAEDMAGVFDIDLDQPEDAGSEDELE----EGGQLNESMDH ::.:::.::. : . .: : : .. : : . NP_003 MAAVFDLDLETEEGSEGEGEPELSPADACPLAE-LRA 10 20 30 60 70 80 90 100 110 pF1KB4 GGVGPYELGMEHCEKFEISETSVNRGPEKIRPECFELLRVLGKGGYGKVFQVRKVTGANT .:. : .: : :. :..::::: :::.: :.:::::::::::::::::::::: :.: NP_003 AGLEP--VG--HYEEVELTETSVNVGPERIGPHCFELLRVLGKGGYGKVFQVRKVQGTNL 40 50 60 70 80 90 120 130 140 150 160 170 pF1KB4 GKIFAMKVLKKAMIVRNAKDTAHTKAERNILEEVKHPFIVDLIYAFQTGGKLYLILEYLS :::.:::::.:: :::::::::::.::::::: :::::::.: :::::::::::::: :: NP_003 GKIYAMKVLRKAKIVRNAKDTAHTRAERNILESVKHPFIVELAYAFQTGGKLYLILECLS 100 110 120 130 140 150 180 190 200 210 220 230 pF1KB4 GGELFMQLEREGIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTD ::::: .:::::::.:::::::::::..::::::..::::::::::::::. :::.:::: NP_003 GGELFTHLEREGIFLEDTACFYLAEITLALGHLHSQGIIYRDLKPENIMLSSQGHIKLTD 160 170 180 190 200 210 240 250 260 270 280 290 pF1KB4 FGLCKESIHDGTVTHTFCGTIEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGE :::::::::.:.:::::::::::::::::.:::::::::::::::::::::::.::::.: NP_003 FGLCKESIHEGAVTHTFCGTIEYMAPEILVRSGHNRAVDWWSLGALMYDMLTGSPPFTAE 220 230 240 250 260 270 300 310 320 330 340 350 pF1KB4 NRKKTIDKILKCKLNLPPYLTQEARDLLKKLLKRNAASRLGAGPGDAGEVQAHPFFRHIN :::::.:::.. :: :::::: .::::.::.:::: ..:.:.:::::..:: ::::::.: NP_003 NRKKTMDKIIRGKLALPPYLTPDARDLVKKFLKRNPSQRIGGGPGDAADVQRHPFFRHMN 280 290 300 310 320 330 360 370 380 390 400 410 pF1KB4 WEELLARKVEPPFKPLLQSEEDVSQFDSKFTRQTPVDSPDDSTLSESANQVFLGFTYVAP :..::: .:.:::.: :::::::::::..::::::::::::..:::::::.::::::::: NP_003 WDDLLAWRVDPPFRPCLQSEEDVSQFDTRFTRQTPVDSPDDTALSESANQAFLGFTYVAP 340 350 360 370 380 390 420 430 440 450 460 470 pF1KB4 SVLESVKEKFSFEPKIRSPRRFIGSPRTPVSPVKFSPGDFWGRGASASTANPQTPVEYPM :::.:.:: :::.::.:::::. .:::.::::.:::: : : : : :. :.: :. NP_003 SVLDSIKEGFSFQPKLRSPRRLNSSPRAPVSPLKFSP--FEGFRPSPSL--PE-PTELPL 400 410 420 430 440 480 490 500 510 520 pF1KB4 ETSGIEQMDVTMSGEASAPLPIRQPNSGPYKKQAFPMISKRPEHLRMNL . ..:::::: : :: :.. NP_003 PP-----LLPPPPPSTTAPLPIRPP-SGTKKSKRGRGRPGR 450 460 470 480 >>XP_016880421 (OMIM: 608938) PREDICTED: ribosomal prote (322 aa) initn: 2196 init1: 2196 opt: 2196 Z-score: 944.6 bits: 183.7 E(85289): 7.1e-46 Smith-Waterman score: 2196; 100.0% identity (100.0% similar) in 322 aa overlap (204-525:1-322) 180 190 200 210 220 230 pF1KB4 YLSGGELFMQLEREGIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVK :::::::::::::::::::::::::::::: XP_016 MALGHLHQKGIIYRDLKPENIMLNHQGHVK 10 20 30 240 250 260 270 280 290 pF1KB4 LTDFGLCKESIHDGTVTHTFCGTIEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LTDFGLCKESIHDGTVTHTFCGTIEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPF 40 50 60 70 80 90 300 310 320 330 340 350 pF1KB4 TGENRKKTIDKILKCKLNLPPYLTQEARDLLKKLLKRNAASRLGAGPGDAGEVQAHPFFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TGENRKKTIDKILKCKLNLPPYLTQEARDLLKKLLKRNAASRLGAGPGDAGEVQAHPFFR 100 110 120 130 140 150 360 370 380 390 400 410 pF1KB4 HINWEELLARKVEPPFKPLLQSEEDVSQFDSKFTRQTPVDSPDDSTLSESANQVFLGFTY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HINWEELLARKVEPPFKPLLQSEEDVSQFDSKFTRQTPVDSPDDSTLSESANQVFLGFTY 160 170 180 190 200 210 420 430 440 450 460 470 pF1KB4 VAPSVLESVKEKFSFEPKIRSPRRFIGSPRTPVSPVKFSPGDFWGRGASASTANPQTPVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VAPSVLESVKEKFSFEPKIRSPRRFIGSPRTPVSPVKFSPGDFWGRGASASTANPQTPVE 220 230 240 250 260 270 480 490 500 510 520 pF1KB4 YPMETSGIEQMDVTMSGEASAPLPIRQPNSGPYKKQAFPMISKRPEHLRMNL :::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YPMETSGIEQMDVTMSGEASAPLPIRQPNSGPYKKQAFPMISKRPEHLRMNL 280 290 300 310 320 >>XP_016880419 (OMIM: 608938) PREDICTED: ribosomal prote (322 aa) initn: 2196 init1: 2196 opt: 2196 Z-score: 944.6 bits: 183.7 E(85289): 7.1e-46 Smith-Waterman score: 2196; 100.0% identity (100.0% similar) in 322 aa overlap (204-525:1-322) 180 190 200 210 220 230 pF1KB4 YLSGGELFMQLEREGIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVK :::::::::::::::::::::::::::::: XP_016 MALGHLHQKGIIYRDLKPENIMLNHQGHVK 10 20 30 240 250 260 270 280 290 pF1KB4 LTDFGLCKESIHDGTVTHTFCGTIEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LTDFGLCKESIHDGTVTHTFCGTIEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPF 40 50 60 70 80 90 300 310 320 330 340 350 pF1KB4 TGENRKKTIDKILKCKLNLPPYLTQEARDLLKKLLKRNAASRLGAGPGDAGEVQAHPFFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TGENRKKTIDKILKCKLNLPPYLTQEARDLLKKLLKRNAASRLGAGPGDAGEVQAHPFFR 100 110 120 130 140 150 360 370 380 390 400 410 pF1KB4 HINWEELLARKVEPPFKPLLQSEEDVSQFDSKFTRQTPVDSPDDSTLSESANQVFLGFTY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HINWEELLARKVEPPFKPLLQSEEDVSQFDSKFTRQTPVDSPDDSTLSESANQVFLGFTY 160 170 180 190 200 210 420 430 440 450 460 470 pF1KB4 VAPSVLESVKEKFSFEPKIRSPRRFIGSPRTPVSPVKFSPGDFWGRGASASTANPQTPVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VAPSVLESVKEKFSFEPKIRSPRRFIGSPRTPVSPVKFSPGDFWGRGASASTANPQTPVE 220 230 240 250 260 270 480 490 500 510 520 pF1KB4 YPMETSGIEQMDVTMSGEASAPLPIRQPNSGPYKKQAFPMISKRPEHLRMNL :::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YPMETSGIEQMDVTMSGEASAPLPIRQPNSGPYKKQAFPMISKRPEHLRMNL 280 290 300 310 320 525 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 14:59:12 2016 done: Thu Nov 3 14:59:14 2016 Total Scan time: 10.040 Total Display time: 0.080 Function used was FASTA [36.3.4 Apr, 2011]