FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB4426, 272 aa 1>>>pF1KB4426 272 - 272 aa - 272 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.8937+/-0.000318; mu= 13.7083+/- 0.020 mean_var=107.8321+/-21.160, 0's: 0 Z-trim(119.5): 86 B-trim: 52 in 1/50 Lambda= 0.123509 statistics sampled from 33557 (33655) to 33557 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.763), E-opt: 0.2 (0.395), width: 16 Scan time: 7.660 The best scores are: opt bits E(85289) NP_000590 (OMIM: 146734) insulin-like growth facto ( 272) 1915 351.2 1.2e-96 XP_016867641 (OMIM: 146732) PREDICTED: insulin-lik ( 291) 806 153.7 3.7e-37 NP_000589 (OMIM: 146732) insulin-like growth facto ( 291) 806 153.7 3.7e-37 NP_001543 (OMIM: 146733) insulin-like growth facto ( 258) 450 90.2 4.3e-18 NP_001013416 (OMIM: 146732) insulin-like growth fa ( 297) 405 82.2 1.2e-15 NP_000587 (OMIM: 146730) insulin-like growth facto ( 259) 346 71.7 1.6e-12 NP_002169 (OMIM: 146735) insulin-like growth facto ( 240) 338 70.2 4.1e-12 NP_000588 (OMIM: 146731) insulin-like growth facto ( 328) 296 62.8 9.2e-10 XP_016874753 (OMIM: 146735) PREDICTED: insulin-lik ( 136) 257 55.5 6e-08 NP_001300922 (OMIM: 146731) insulin-like growth fa ( 159) 216 48.3 1.1e-05 NP_001300921 (OMIM: 146731) insulin-like growth fa ( 159) 216 48.3 1.1e-05 NP_001300919 (OMIM: 146731) insulin-like growth fa ( 181) 216 48.3 1.2e-05 NP_001240764 (OMIM: 602867,614224) insulin-like gr ( 279) 197 45.1 0.00017 NP_001544 (OMIM: 602867,614224) insulin-like growt ( 282) 197 45.1 0.00017 NP_001191282 (OMIM: 607989) testican-3 isoform 4 [ ( 316) 184 42.9 0.00092 NP_001238896 (OMIM: 607989) testican-3 isoform 11 ( 338) 184 42.9 0.00096 NP_001191284 (OMIM: 607989) testican-3 isoform 6 [ ( 340) 184 42.9 0.00097 NP_001191283 (OMIM: 607989) testican-3 isoform 5 [ ( 344) 184 42.9 0.00097 NP_001129076 (OMIM: 601521) endothelial cell-speci ( 134) 178 41.5 0.001 NP_001191281 (OMIM: 607989) testican-3 isoform 3 [ ( 385) 184 42.9 0.0011 NP_001191285 (OMIM: 607989) testican-3 isoform 7 p ( 393) 184 43.0 0.0011 XP_016863747 (OMIM: 607989) PREDICTED: testican-3 ( 433) 184 43.0 0.0012 NP_001035249 (OMIM: 607989) testican-3 isoform 1 p ( 433) 184 43.0 0.0012 NP_058646 (OMIM: 607989) testican-3 isoform 2 prec ( 436) 184 43.0 0.0012 XP_011530320 (OMIM: 607989) PREDICTED: testican-3 ( 436) 184 43.0 0.0012 XP_016863746 (OMIM: 607989) PREDICTED: testican-3 ( 445) 184 43.0 0.0012 NP_002766 (OMIM: 600142,602194,610149,616779) seri ( 480) 183 42.9 0.0014 NP_008967 (OMIM: 601521) endothelial cell-specific ( 184) 172 40.5 0.0027 NP_004589 (OMIM: 602264) testican-1 precursor [Hom ( 439) 175 41.4 0.0035 XP_011538706 (OMIM: 607988) PREDICTED: testican-2 ( 421) 173 41.0 0.0044 NP_001231879 (OMIM: 607988) testican-2 isoform 2 p ( 424) 173 41.0 0.0044 NP_055582 (OMIM: 607988) testican-2 isoform 2 prec ( 424) 173 41.0 0.0044 XP_005264414 (OMIM: 606189) PREDICTED: cysteine-ri ( 978) 172 41.2 0.0092 >>NP_000590 (OMIM: 146734) insulin-like growth factor-bi (272 aa) initn: 1915 init1: 1915 opt: 1915 Z-score: 1856.4 bits: 351.2 E(85289): 1.2e-96 Smith-Waterman score: 1915; 100.0% identity (100.0% similar) in 272 aa overlap (1-272:1-272) 10 20 30 40 50 60 pF1KB4 MVLLTAVLLLLAAYAGPAQSLGSFVHCEPCDEKALSMCPPSPLGCELVKEPGCGCCMTCA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 MVLLTAVLLLLAAYAGPAQSLGSFVHCEPCDEKALSMCPPSPLGCELVKEPGCGCCMTCA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 LAEGQSCGVYTERCAQGLRCLPRQDEEKPLHALLHGRGVCLNEKSYREQVKIERDSREHE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 LAEGQSCGVYTERCAQGLRCLPRQDEEKPLHALLHGRGVCLNEKSYREQVKIERDSREHE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 EPTTSEMAEETYSPKIFRPKHTRISELKAEAVKKDRRKKLTQSKFVGGAENTAHPRIISA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 EPTTSEMAEETYSPKIFRPKHTRISELKAEAVKKDRRKKLTQSKFVGGAENTAHPRIISA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 PEMRQESEQGPCRRHMEASLQELKASPRMVPRAVYLPNCDRKGFYKRKQCKPSRGRKRGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 PEMRQESEQGPCRRHMEASLQELKASPRMVPRAVYLPNCDRKGFYKRKQCKPSRGRKRGI 190 200 210 220 230 240 250 260 270 pF1KB4 CWCVDKYGMKLPGMEYVDGDFQCHTFDSSNVE :::::::::::::::::::::::::::::::: NP_000 CWCVDKYGMKLPGMEYVDGDFQCHTFDSSNVE 250 260 270 >>XP_016867641 (OMIM: 146732) PREDICTED: insulin-like gr (291 aa) initn: 812 init1: 372 opt: 806 Z-score: 788.0 bits: 153.7 E(85289): 3.7e-37 Smith-Waterman score: 817; 44.0% identity (67.6% similar) in 293 aa overlap (3-268:8-290) 10 20 30 40 pF1KB4 MVLLTAVLLLLAAYAGP------AQS--LGSFVHCEPCDEKALSMCPPSPLGC-E : .:.: ::. :: :.: :: :.::::: .::..: : : : : XP_016 MQRARPTLWAAALTLLVLLRGPPVARAGASSAGLGPVVRCEPCDARALAQCAPPPAVCAE 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB4 LVKEPGCGCCMTCALAEGQSCGVYTERCAQGLRCLPRQDEEKPLHALLHGRGVCLNEKSY ::.:::::::.::::.::: ::.:::::..:::: : :: .::.::: :::.:.: .. XP_016 LVREPGCGCCLTCALSEGQPCGIYTERCGSGLRCQPSPDEARPLQALLDGRGLCVNASAV 70 80 90 100 110 120 110 120 130 140 150 pF1KB4 RE----------------QVKIERDSREHEEPTTSEMAEETYSPKIFRPKHTRISELKAE . . . .:.. : :..: .... .:: :.: :..: .: XP_016 SRLRAYLLPAPPAPGNASESEEDRSAGSVESPSVSS-THRVSDPK-FHPLHSKIIIIKKG 130 140 150 160 170 160 170 180 190 200 210 pF1KB4 AVKKDRRKKLTQSKFVGGAENTAHPRIISAPEMRQESEQGPCRRHMEASLQELKASPRMV .: ..: :. . ..: . : ..:.: :::::.:: .:..:: . XP_016 HAKDSQRYKVDYESQSTDTQNFSS-------ESKRETEYGPCRREMEDTLNHLKFLNVLS 180 190 200 210 220 230 220 230 240 250 260 pF1KB4 PRAVYLPNCDRKGFYKRKQCKPSRGRKRGICWCVDKYGMKLPGMEYVDG--DFQCHTFDS ::.:..::::.:::::.:::.::.:::::.::::::::. :::. . : : .:....: XP_016 PRGVHIPNCDKKGFYKKKQCRPSKGRKRGFCWCVDKYGQPLPGYT-TKGKEDVHCYSMQS 240 250 260 270 280 290 270 pF1KB4 SNVE XP_016 K >>NP_000589 (OMIM: 146732) insulin-like growth factor-bi (291 aa) initn: 812 init1: 372 opt: 806 Z-score: 788.0 bits: 153.7 E(85289): 3.7e-37 Smith-Waterman score: 817; 44.0% identity (67.6% similar) in 293 aa overlap (3-268:8-290) 10 20 30 40 pF1KB4 MVLLTAVLLLLAAYAGP------AQS--LGSFVHCEPCDEKALSMCPPSPLGC-E : .:.: ::. :: :.: :: :.::::: .::..: : : : : NP_000 MQRARPTLWAAALTLLVLLRGPPVARAGASSAGLGPVVRCEPCDARALAQCAPPPAVCAE 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB4 LVKEPGCGCCMTCALAEGQSCGVYTERCAQGLRCLPRQDEEKPLHALLHGRGVCLNEKSY ::.:::::::.::::.::: ::.:::::..:::: : :: .::.::: :::.:.: .. NP_000 LVREPGCGCCLTCALSEGQPCGIYTERCGSGLRCQPSPDEARPLQALLDGRGLCVNASAV 70 80 90 100 110 120 110 120 130 140 150 pF1KB4 RE----------------QVKIERDSREHEEPTTSEMAEETYSPKIFRPKHTRISELKAE . . . .:.. : :..: .... .:: :.: :..: .: NP_000 SRLRAYLLPAPPAPGNASESEEDRSAGSVESPSVSS-THRVSDPK-FHPLHSKIIIIKKG 130 140 150 160 170 160 170 180 190 200 210 pF1KB4 AVKKDRRKKLTQSKFVGGAENTAHPRIISAPEMRQESEQGPCRRHMEASLQELKASPRMV .: ..: :. . ..: . : ..:.: :::::.:: .:..:: . NP_000 HAKDSQRYKVDYESQSTDTQNFSS-------ESKRETEYGPCRREMEDTLNHLKFLNVLS 180 190 200 210 220 230 220 230 240 250 260 pF1KB4 PRAVYLPNCDRKGFYKRKQCKPSRGRKRGICWCVDKYGMKLPGMEYVDG--DFQCHTFDS ::.:..::::.:::::.:::.::.:::::.::::::::. :::. . : : .:....: NP_000 PRGVHIPNCDKKGFYKKKQCRPSKGRKRGFCWCVDKYGQPLPGYT-TKGKEDVHCYSMQS 240 250 260 270 280 290 270 pF1KB4 SNVE NP_000 K >>NP_001543 (OMIM: 146733) insulin-like growth factor-bi (258 aa) initn: 623 init1: 373 opt: 450 Z-score: 445.9 bits: 90.2 E(85289): 4.3e-18 Smith-Waterman score: 658; 40.8% identity (62.8% similar) in 277 aa overlap (1-269:1-255) 10 20 30 40 50 pF1KB4 MVLLTAVLLLLAAYAGPAQSLGSF-VHCEPCDEKALSMCPPSPLGCE-LVKEPGCGCCMT :. : : :: : :::. :::. .:: ::.:. :. : : :.::: ::.::::::: : NP_001 MLPLCLVAALLLA-AGPGPSLGDEAIHCPPCSEEKLARCRP-PVGCEELVREPGCGCCAT 10 20 30 40 50 60 70 80 90 100 110 pF1KB4 CALAEGQSCGVYTERCAQGLRCLPRQDEEKPLHALLHGRGVCLNEKSYREQVKIE--RDS :::. :. ::::: ::..:::: : . :::::.:.::.:::. : ..:: ..: NP_001 CALGLGMPCGVYTPRCGSGLRCYPPRGVEKPLHTLMHGQGVCM------ELAEIEAIQES 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB4 REHEEPTTSEMAEETYSPKIFRPKHTRISELKAEAVKKDRRKKLTQSKFVGGAENTAHPR . . .. ....:: : : : : .:: . . : :. .. :.: NP_001 LQPSDKDEGDHPNNSFSPC---SAHDRRCLQKHFAKIRDRSTSGGKMKVNGAPREDARP- 120 130 140 150 160 180 190 200 210 220 230 pF1KB4 IISAPEMRQESEQGPCRRHMEASLQELKASPRMVPRAVYL---PNCDRKGFYKRKQCKPS .: :: :. ... .:..: :: . . .:. :::::.: .. :::.:. NP_001 ---VP-------QGSCQSELHRALERLAASQSRTHEDLYIIPIPNCDRNGNFHPKQCHPA 170 180 190 200 210 240 250 260 270 pF1KB4 RGRKRGICWCVD-KYGMKLPGMEYVDGDFQCHTFDSSNVE .:: ::::: : :.:::: :...:: . .: NP_001 LDGQRGKCWCVDRKTGVKLPGGLEPKGELDCHQLADSFRE 220 230 240 250 >>NP_001013416 (OMIM: 146732) insulin-like growth factor (297 aa) initn: 709 init1: 372 opt: 405 Z-score: 401.7 bits: 82.2 E(85289): 1.2e-15 Smith-Waterman score: 806; 44.1% identity (66.0% similar) in 297 aa overlap (3-268:8-296) 10 20 30 40 pF1KB4 MVLLTAVLLLLAAYAGP------AQS--LGSFVHCEPCDEKALSMCPPSPLGC-E : .:.: ::. :: :.: :: :.::::: .::..: : : : : NP_001 MQRARPTLWAAALTLLVLLRGPPVARAGASSAGLGPVVRCEPCDARALAQCAPPPAVCAE 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB4 LVKEPGCGCCMTCALAEGQSCGVYTERCAQGLRCLPRQDEEKPLHALLHGRGVCLNEKSY ::.:::::::.::::.::: ::.:::::..:::: : :: .::.::: :::.:.: .. NP_001 LVREPGCGCCLTCALSEGQPCGIYTERCGSGLRCQPSPDEARPLQALLDGRGLCVNASAV 70 80 90 100 110 120 110 120 130 140 pF1KB4 -REQVKIERDSREHEEP----TTSEMAEE-----TYSPKI----------FRPKHTRISE : .. . :: ..:: :. . ::.. :.: :..: NP_001 SRLRAYLLPAPPAPGEPPAPGNASESEEDRSAGSVESPSVSSTHRVSDPKFHPLHSKIII 130 140 150 160 170 180 150 160 170 180 190 200 pF1KB4 LKAEAVKKDRRKKLTQSKFVGGAENTAHPRIISAPEMRQESEQGPCRRHMEASLQELKAS .: .: ..: :. . ..: . : ..:.: :::::.:: .:..:: NP_001 IKKGHAKDSQRYKVDYESQSTDTQNFSS-------ESKRETEYGPCRREMEDTLNHLKFL 190 200 210 220 230 210 220 230 240 250 260 pF1KB4 PRMVPRAVYLPNCDRKGFYKRKQCKPSRGRKRGICWCVDKYGMKLPGMEYVDG--DFQCH . ::.:..::::.:::::.:::.::.:::::.::::::::. :::. . : : .:. NP_001 NVLSPRGVHIPNCDKKGFYKKKQCRPSKGRKRGFCWCVDKYGQPLPGYT-TKGKEDVHCY 240 250 260 270 280 290 270 pF1KB4 TFDSSNVE ...: NP_001 SMQSK >>NP_000587 (OMIM: 146730) insulin-like growth factor-bi (259 aa) initn: 470 init1: 241 opt: 346 Z-score: 345.7 bits: 71.7 E(85289): 1.6e-12 Smith-Waterman score: 495; 32.0% identity (58.3% similar) in 266 aa overlap (7-266:12-254) 10 20 30 40 50 pF1KB4 MVLLTAVLLLLAAYAGPAQSLGSFVHCEPCDEKALSMCPPSPLGC-ELVKEPGCG :::::.. .: . :. .: ::. . :..::: .: :... ::: NP_000 MSEVPVARVWLVLLLLTVQVG--VTAGAPWQCAPCSAEKLALCPPVSASCSEVTRSAGCG 10 20 30 40 50 60 70 80 90 100 110 pF1KB4 CCMTCALAEGQSCGVYTERCAQGLRCLPRQDEEKPLHALLHGRGVCLNEKSYREQVKIER :: ::: : .::: : :::.:: : :..::::: .:.:.:..:.. : NP_000 CCPMCALPLGAACGVATARCARGLSCRALPGEQQPLHALTRGQGACVQESDASAPHAAEA 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB4 DSREHEEPTTSEMAEETYSPKIFRPKHTRISELKAEAVKKDRRKKLTQSKFVGGAENTAH : : : ..:..:: ... : . ... : . : . :. NP_000 GS--PESPESTEITEE----ELLDNFHLMAPSEEDHSILWD-----AISTYDGS------ 120 130 140 150 160 180 190 200 210 220 230 pF1KB4 PRIISAPEMRQESEQGPCR----RHMEASLQELKASPRMVPRAVYLPNCDRKGFYKRKQC . . . .... .: ::: : .:. . ..: . . . :::::...:::. .:: NP_000 -KALHVTNIKKWKE--PCRIELYRVVESLAKAQETSGEEISK-FYLPNCNKNGFYHSRQC 170 180 190 200 210 240 250 260 270 pF1KB4 KPSRGRKRGICWCVDKY-GMKLPGMEYVDGDFQCHTFDSSNVE . : . :.:::: . : ..:: . :: .:. . NP_000 ETSMDGEAGLCWCVYPWNGKRIPGSPEIRGDPNCQIYFNVQN 220 230 240 250 >>NP_002169 (OMIM: 146735) insulin-like growth factor-bi (240 aa) initn: 586 init1: 308 opt: 338 Z-score: 338.4 bits: 70.2 E(85289): 4.1e-12 Smith-Waterman score: 531; 35.1% identity (59.7% similar) in 268 aa overlap (3-268:6-239) 10 20 30 40 50 pF1KB4 MVLLTAVLLLLAAYAGPAQSLGSFVHCEPCDEKALSMCPPSPLGCELVKEPGCGCCM :: .::::: . :. :....: : . . . :: . . : :. :: NP_002 MTPHRLLPPLLLLLALLLA-ASPGGALARCPGCGQGVQAGCPGGCVEEEDGGSPAEGCAE 10 20 30 40 50 60 70 80 90 100 110 pF1KB4 T--CALAEGQSCGVYTERCAQGLRCLPRQDEEKPLHALLHGRGVCLNEKSYREQVKIERD . : ::: ::::: :: ::.: : .:.: ::.::: ::: :: .. NP_002 AEGCLRREGQECGVYTPNCAPGLQCHPPKDDEAPLRALLLGRGRCLPARA---------- 60 70 80 90 100 120 130 140 150 160 170 pF1KB4 SREHEEPTTSEMAEETYSPKIFRPKHTRISELKAEAVKKDRRKKLTQSKFVGGAENTAHP :. .::: .:: .:. . : .: .. :.. : . . ..: NP_002 ------PA---VAEE--NPKESKPQ-------AGTARPQDVNRR-DQQRNPGTSTTPSQP 110 120 130 140 150 180 190 200 210 220 230 pF1KB4 RIISAPEMRQESEQGPCRRHMEASLQELKASPRMVPRAVYLPNCDRKGFYKRKQCKPSRG .. :..:.::::::... ::.:.. ...:.::::..:::...::. :.: NP_002 NSAGV----QDTEMGPCRRHLDSVLQQLQTEVYRGAQTLYVPNCDHRGFYRKRQCRSSQG 160 170 180 190 200 240 250 260 270 pF1KB4 RKRGICWCVDKYGMKLPGMEYVDGDFQCHTFDSSNVE ..:: :::::..: .::: .:. .: : .: NP_002 QRRGPCWCVDRMGKSLPGSPDGNGSSSCPTGSSG 210 220 230 240 >>NP_000588 (OMIM: 146731) insulin-like growth factor-bi (328 aa) initn: 491 init1: 280 opt: 296 Z-score: 296.2 bits: 62.8 E(85289): 9.2e-10 Smith-Waterman score: 507; 33.1% identity (57.5% similar) in 299 aa overlap (3-266:20-312) 10 20 30 40 pF1KB4 MVLLTAVLLLLAAYAGPAQSLGSFV-HCEPCDEKALSMCPPSP :: .::::.: .: . . . . .: :: . :. : : : NP_000 MLPRVGCPALPLPPPPLLPLLPLLLLLLGASGGGGGARAEVLFRCPPCTPERLAACGPPP 10 20 30 40 50 60 50 60 70 80 pF1KB4 LG---------------C-ELVKEPGCGCCMTCALAEGQSCGVYTERCAQGLRCLPRQDE .. : :::.::::::: .:: ::..::::: ::.::::: :. NP_000 VAPPAAVAAVAGGARMPCAELVREPGCGCCSVCARLEGEACGVYTPRCGQGLRCYPHPGS 70 80 90 100 110 120 90 100 110 120 130 pF1KB4 EKPLHALLHGRGVCLNEKSYR-----EQVKIERDSREH----EEPTTSEMAEETYSPKIF : ::.::. :.:.: .... . ::: . :.. . :. . : : . . NP_000 ELPLQALVMGEGTCEKRRDAEYGASPEQVADNGDDHSEGGLVENHVDSTMNMLGGGGSAG 130 140 150 160 170 180 140 150 160 170 180 190 pF1KB4 R-PKHTRISELKAEAVKKDRRKKLTQSKFVGGAENTAHPRIISAPEMRQESEQGPCRRHM : : .. ..:: :: :.:.:... : . : . ..: . ::.... NP_000 RKPLKSGMKEL---AV---FREKVTEQHRQMGKGGKHHLGLEEPKKLRPPPARTPCQQEL 190 200 210 220 230 200 210 220 230 240 pF1KB4 EASLQELKA-------SPRMVPRAVYLPNCDRKGFYKRKQCKPSRGRKRGICWCVDKYGM . :..... .: ....::::..:.:. :::: : . .:: ::::. NP_000 DQVLERISTMRLPDERGPLEHLYSLHIPNCDKHGLYNLKQCKMSLNGQRGECWCVNPNTG 240 250 260 270 280 290 250 260 270 pF1KB4 KL-PGMEYVDGDFQCHTFDSSNVE :: : . :: .:: : NP_000 KLIQGAPTIRGDPECHLFYNEQQEARGVHTQRMQ 300 310 320 >>XP_016874753 (OMIM: 146735) PREDICTED: insulin-like gr (136 aa) initn: 207 init1: 207 opt: 257 Z-score: 263.7 bits: 55.5 E(85289): 6e-08 Smith-Waterman score: 257; 41.9% identity (61.0% similar) in 105 aa overlap (3-105:6-109) 10 20 30 40 50 pF1KB4 MVLLTAVLLLLAAYAGPAQSLGSFVHCEPCDEKALSMCPPSPLGCELVKEPGCGCCM :: .::::: . :. :....: : . . . :: . . : :. :: XP_016 MTPHRLLPPLLLLLALLLA-ASPGGALARCPGCGQGVQAGCPGGCVEEEDGGSPAEGCAE 10 20 30 40 50 60 70 80 90 100 110 pF1KB4 T--CALAEGQSCGVYTERCAQGLRCLPRQDEEKPLHALLHGRGVCLNEKSYREQVKIERD . : ::: ::::: :: ::.: : .:.: ::.::: ::: :: .. XP_016 AEGCLRREGQECGVYTPNCAPGLQCHPPKDDEAPLRALLLGRGRCLPARAPAVLSSPRTL 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB4 SREHEEPTTSEMAEETYSPKIFRPKHTRISELKAEAVKKDRRKKLTQSKFVGGAENTAHP XP_016 RKLSPEPGATCSCRGES 120 130 >>NP_001300922 (OMIM: 146731) insulin-like growth factor (159 aa) initn: 226 init1: 153 opt: 216 Z-score: 223.3 bits: 48.3 E(85289): 1.1e-05 Smith-Waterman score: 216; 29.7% identity (58.5% similar) in 118 aa overlap (157-266:26-143) 130 140 150 160 170 180 pF1KB4 MAEETYSPKIFRPKHTRISELKAEAVKKDRRKKLTQSKFVGGAENTAHPRIISAPEMRQE :.:.:... : . : . ..: NP_001 MNMLGGGGSAGRKPLKSGMKELAVFREKVTEQHRQMGKGGKHHLGLEEPKKLRPP 10 20 30 40 50 190 200 210 220 230 pF1KB4 SEQGPCRRHMEASLQELKA-------SPRMVPRAVYLPNCDRKGFYKRKQCKPSRGRKRG . ::..... :..... .: ....::::..:.:. :::: : . .:: NP_001 PARTPCQQELDQVLERISTMRLPDERGPLEHLYSLHIPNCDKHGLYNLKQCKMSLNGQRG 60 70 80 90 100 110 240 250 260 270 pF1KB4 ICWCVDKYGMKL-PGMEYVDGDFQCHTFDSSNVE ::::. :: : . :: .:: : NP_001 ECWCVNPNTGKLIQGAPTIRGDPECHLFYNEQQEARGVHTQRMQ 120 130 140 150 272 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 03:00:52 2016 done: Fri Nov 4 03:00:53 2016 Total Scan time: 7.660 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]