FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB4450, 380 aa 1>>>pF1KB4450 380 - 380 aa - 380 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.4919+/-0.000415; mu= 16.5087+/- 0.026 mean_var=109.1432+/-24.890, 0's: 0 Z-trim(113.2): 720 B-trim: 1133 in 1/52 Lambda= 0.122765 statistics sampled from 21615 (22473) to 21615 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.628), E-opt: 0.2 (0.263), width: 16 Scan time: 7.470 The best scores are: opt bits E(85289) NP_005152 (OMIM: 600052) apelin receptor [Homo sap ( 380) 2585 469.0 7.9e-132 NP_033611 (OMIM: 106165,145500,267430) type-1 angi ( 359) 652 126.6 8.7e-29 NP_000676 (OMIM: 106165,145500,267430) type-1 angi ( 359) 652 126.6 8.7e-29 NP_114438 (OMIM: 106165,145500,267430) type-1 angi ( 388) 652 126.7 9.2e-29 NP_114038 (OMIM: 106165,145500,267430) type-1 angi ( 394) 652 126.7 9.3e-29 NP_004826 (OMIM: 106165,145500,267430) type-1 angi ( 394) 652 126.7 9.3e-29 XP_011535835 (OMIM: 300034) PREDICTED: type-2 angi ( 363) 585 114.8 3.3e-25 NP_000677 (OMIM: 300034) type-2 angiotensin II rec ( 363) 585 114.8 3.3e-25 NP_004063 (OMIM: 602351) chemokine-like receptor 1 ( 371) 544 107.5 5.1e-23 XP_016874309 (OMIM: 602351) PREDICTED: chemokine-l ( 371) 544 107.5 5.1e-23 NP_001135816 (OMIM: 602351) chemokine-like recepto ( 373) 544 107.5 5.1e-23 NP_001135817 (OMIM: 602351) chemokine-like recepto ( 373) 544 107.5 5.1e-23 NP_001135815 (OMIM: 602351) chemokine-like recepto ( 373) 544 107.5 5.1e-23 NP_000903 (OMIM: 165196) kappa-type opioid recepto ( 380) 539 106.7 9.6e-23 NP_001305426 (OMIM: 165196) kappa-type opioid rece ( 409) 539 106.7 1e-22 NP_005305 (OMIM: 305670) gastrin-releasing peptide ( 384) 521 103.5 8.8e-22 NP_000614 (OMIM: 113503) B2 bradykinin receptor [H ( 391) 518 103.0 1.3e-21 NP_000701 (OMIM: 600337) B1 bradykinin receptor [H ( 353) 502 100.1 8.6e-21 NP_002502 (OMIM: 162341) neuromedin-B receptor iso ( 390) 487 97.5 5.8e-20 NP_001264929 (OMIM: 300086) lysophosphatidic acid ( 370) 483 96.7 9.1e-20 XP_016884927 (OMIM: 300086) PREDICTED: lysophospha ( 370) 483 96.7 9.1e-20 NP_005287 (OMIM: 300086) lysophosphatidic acid rec ( 370) 483 96.7 9.1e-20 XP_006724702 (OMIM: 300086) PREDICTED: lysophospha ( 370) 483 96.7 9.1e-20 XP_016884926 (OMIM: 300086) PREDICTED: lysophospha ( 370) 483 96.7 9.1e-20 XP_005262183 (OMIM: 300086) PREDICTED: lysophospha ( 370) 483 96.7 9.1e-20 NP_001040 (OMIM: 182451) somatostatin receptor typ ( 391) 476 95.5 2.2e-19 NP_001005738 (OMIM: 136538) N-formyl peptide recep ( 351) 474 95.1 2.7e-19 NP_001453 (OMIM: 136538) N-formyl peptide receptor ( 351) 474 95.1 2.7e-19 XP_006723183 (OMIM: 136538) PREDICTED: N-formyl pe ( 351) 474 95.1 2.7e-19 XP_016882031 (OMIM: 136538) PREDICTED: N-formyl pe ( 351) 474 95.1 2.7e-19 NP_005758 (OMIM: 278150,609239) lysophosphatidic a ( 344) 470 94.4 4.3e-19 NP_001155969 (OMIM: 278150,609239) lysophosphatidi ( 344) 470 94.4 4.3e-19 NP_001155970 (OMIM: 278150,609239) lysophosphatidi ( 344) 470 94.4 4.3e-19 NP_001041 (OMIM: 182452) somatostatin receptor typ ( 369) 468 94.1 5.8e-19 XP_011528651 (OMIM: 182453) PREDICTED: somatostati ( 418) 468 94.1 6.3e-19 XP_006724374 (OMIM: 182453) PREDICTED: somatostati ( 418) 468 94.1 6.3e-19 XP_016884412 (OMIM: 182453) PREDICTED: somatostati ( 418) 468 94.1 6.3e-19 NP_001042 (OMIM: 182453) somatostatin receptor typ ( 418) 468 94.1 6.3e-19 XP_005261778 (OMIM: 182453) PREDICTED: somatostati ( 418) 468 94.1 6.3e-19 XP_016884413 (OMIM: 182453) PREDICTED: somatostati ( 418) 468 94.1 6.3e-19 NP_001265616 (OMIM: 182453) somatostatin receptor ( 418) 468 94.1 6.3e-19 NP_001269833 (OMIM: 165196) kappa-type opioid rece ( 291) 463 93.1 9.1e-19 NP_001158195 (OMIM: 173393) platelet-activating fa ( 342) 460 92.6 1.5e-18 NP_000943 (OMIM: 173393) platelet-activating facto ( 342) 460 92.6 1.5e-18 NP_001158194 (OMIM: 173393) platelet-activating fa ( 342) 460 92.6 1.5e-18 NP_001158193 (OMIM: 173393) platelet-activating fa ( 342) 460 92.6 1.5e-18 NP_001043 (OMIM: 182454) somatostatin receptor typ ( 388) 454 91.6 3.3e-18 NP_001264135 (OMIM: 602451) P2Y purinoceptor 6 iso ( 328) 451 91.0 4.3e-18 NP_001264134 (OMIM: 602451) P2Y purinoceptor 6 iso ( 328) 451 91.0 4.3e-18 NP_001264133 (OMIM: 602451) P2Y purinoceptor 6 iso ( 328) 451 91.0 4.3e-18 >>NP_005152 (OMIM: 600052) apelin receptor [Homo sapiens (380 aa) initn: 2585 init1: 2585 opt: 2585 Z-score: 2487.7 bits: 469.0 E(85289): 7.9e-132 Smith-Waterman score: 2585; 100.0% identity (100.0% similar) in 380 aa overlap (1-380:1-380) 10 20 30 40 50 60 pF1KB4 MEEGGDFDNYYGADNQSECEYTDWKSSGALIPAIYMLVFLLGTTGNGLVLWTVFRSSREK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 MEEGGDFDNYYGADNQSECEYTDWKSSGALIPAIYMLVFLLGTTGNGLVLWTVFRSSREK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 RRSADIFIASLAVADLTFVVTLPLWATYTYRDYDWPFGTFFCKLSSYLIFVNMYASVFCL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 RRSADIFIASLAVADLTFVVTLPLWATYTYRDYDWPFGTFFCKLSSYLIFVNMYASVFCL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 TGLSFDRYLAIVRPVANARLRLRVSGAVATAVLWVLAALLAMPVMVLRTTGDLENTTKVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 TGLSFDRYLAIVRPVANARLRLRVSGAVATAVLWVLAALLAMPVMVLRTTGDLENTTKVQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 CYMDYSMVATVSSEWAWEVGLGVSSTTVGFVVPFTIMLTCYFFIAQTIAGHFRKERIEGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 CYMDYSMVATVSSEWAWEVGLGVSSTTVGFVVPFTIMLTCYFFIAQTIAGHFRKERIEGL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 RKRRRLLSIIVVLVVTFALCWMPYHLVKTLYMLGSLLHWPCDFDLFLMNIFPYCTCISYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 RKRRRLLSIIVVLVVTFALCWMPYHLVKTLYMLGSLLHWPCDFDLFLMNIFPYCTCISYV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 NSCLNPFLYAFFDPRFRQACTSMLCCGQSRCAGTSHSSSGEKSASYSSGHSQGPGPNMGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 NSCLNPFLYAFFDPRFRQACTSMLCCGQSRCAGTSHSSSGEKSASYSSGHSQGPGPNMGK 310 320 330 340 350 360 370 380 pF1KB4 GGEQMHEKSIPYSQETLVVD :::::::::::::::::::: NP_005 GGEQMHEKSIPYSQETLVVD 370 380 >>NP_033611 (OMIM: 106165,145500,267430) type-1 angioten (359 aa) initn: 616 init1: 375 opt: 652 Z-score: 637.8 bits: 126.6 E(85289): 8.7e-29 Smith-Waterman score: 652; 32.4% identity (66.4% similar) in 333 aa overlap (30-356:30-354) 10 20 30 40 50 60 pF1KB4 MEEGGDFDNYYGADNQSECEYTDWKSSGALIPAIYMLVFLLGTTGNGLVLWTVFRSSREK .::..: ..:..: ::.::. ... . : NP_033 MILNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 RRSADIFIASLAVADLTFVVTLPLWATYTYRDYDWPFGTFFCKLSSYLIFVNMYASVFCL :..:. .::.::: :..::::::.:: .: ::::...::..: . :.::::: : NP_033 T-VASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLL 70 80 90 100 110 130 140 150 160 170 180 pF1KB4 TGLSFDRYLAIVRPVANARLRLRVSGAVATAVLWVLAALLAMPVMVLRTTGDLENTTKVQ : ::.:::::::.:. . : . . :. ..:.::.: ..:... :.. .:::. . NP_033 TCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITV 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB4 CYMDYSMVATVSSEWAWEVGLGVSSTTVGFVVPFTIMLTCYFFIAQTIAGHFRKERIEGL : . : :.. . .:::.... .::. :: :.:: : .: ... .. .. . NP_033 CAFHYE-----SQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKP- 180 190 200 210 220 230 250 260 270 280 290 pF1KB4 RKRRRLLSIIVVLVVTFALCWMPYHLVKTLYMLGSL-LHWPCDFDLFLMNIFPYCTCISY . ...::...:. : . :.:... : .: .: . : . .. . .: ::.: NP_033 -RNDDIFKIIMAIVLFFFFSWIPHQIFTFLDVLIQLGIIRDCRIADIVDTAMPITICIAY 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB4 VNSCLNPFLYAFFDPRFRQACTSMLCCGQSRCAGTSHSSSGEKSASYS-----SGHSQGP :.::::..:.:. .:.. ..: . . :. :. .. :: :. .. : NP_033 FNNCLNPLFYGFLGKKFKRYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSTKKP 300 310 320 330 340 350 360 370 380 pF1KB4 GPNMGKGGEQMHEKSIPYSQETLVVD .: NP_033 APCFEVE >>NP_000676 (OMIM: 106165,145500,267430) type-1 angioten (359 aa) initn: 616 init1: 375 opt: 652 Z-score: 637.8 bits: 126.6 E(85289): 8.7e-29 Smith-Waterman score: 652; 32.4% identity (66.4% similar) in 333 aa overlap (30-356:30-354) 10 20 30 40 50 60 pF1KB4 MEEGGDFDNYYGADNQSECEYTDWKSSGALIPAIYMLVFLLGTTGNGLVLWTVFRSSREK .::..: ..:..: ::.::. ... . : NP_000 MILNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 RRSADIFIASLAVADLTFVVTLPLWATYTYRDYDWPFGTFFCKLSSYLIFVNMYASVFCL :..:. .::.::: :..::::::.:: .: ::::...::..: . :.::::: : NP_000 T-VASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLL 70 80 90 100 110 130 140 150 160 170 180 pF1KB4 TGLSFDRYLAIVRPVANARLRLRVSGAVATAVLWVLAALLAMPVMVLRTTGDLENTTKVQ : ::.:::::::.:. . : . . :. ..:.::.: ..:... :.. .:::. . NP_000 TCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITV 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB4 CYMDYSMVATVSSEWAWEVGLGVSSTTVGFVVPFTIMLTCYFFIAQTIAGHFRKERIEGL : . : :.. . .:::.... .::. :: :.:: : .: ... .. .. . NP_000 CAFHYE-----SQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKP- 180 190 200 210 220 230 250 260 270 280 290 pF1KB4 RKRRRLLSIIVVLVVTFALCWMPYHLVKTLYMLGSL-LHWPCDFDLFLMNIFPYCTCISY . ...::...:. : . :.:... : .: .: . : . .. . .: ::.: NP_000 -RNDDIFKIIMAIVLFFFFSWIPHQIFTFLDVLIQLGIIRDCRIADIVDTAMPITICIAY 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB4 VNSCLNPFLYAFFDPRFRQACTSMLCCGQSRCAGTSHSSSGEKSASYS-----SGHSQGP :.::::..:.:. .:.. ..: . . :. :. .. :: :. .. : NP_000 FNNCLNPLFYGFLGKKFKRYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSTKKP 300 310 320 330 340 350 360 370 380 pF1KB4 GPNMGKGGEQMHEKSIPYSQETLVVD .: NP_000 APCFEVE >>NP_114438 (OMIM: 106165,145500,267430) type-1 angioten (388 aa) initn: 616 init1: 375 opt: 652 Z-score: 637.4 bits: 126.7 E(85289): 9.2e-29 Smith-Waterman score: 652; 32.4% identity (66.4% similar) in 333 aa overlap (30-356:59-383) 10 20 30 40 50 pF1KB4 MEEGGDFDNYYGADNQSECEYTDWKSSGALIPAIYMLVFLLGTTGNGLVLWTVFRSSRE .::..: ..:..: ::.::. ... . NP_114 KMILNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKL 30 40 50 60 70 80 60 70 80 90 100 110 pF1KB4 KRRSADIFIASLAVADLTFVVTLPLWATYTYRDYDWPFGTFFCKLSSYLIFVNMYASVFC : :..:. .::.::: :..::::::.:: .: ::::...::..: . :.::::: NP_114 KT-VASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFL 90 100 110 120 130 140 120 130 140 150 160 170 pF1KB4 LTGLSFDRYLAIVRPVANARLRLRVSGAVATAVLWVLAALLAMPVMVLRTTGDLENTTKV :: ::.:::::::.:. . : . . :. ..:.::.: ..:... :.. .:::. . NP_114 LTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNIT 150 160 170 180 190 200 180 190 200 210 220 230 pF1KB4 QCYMDYSMVATVSSEWAWEVGLGVSSTTVGFVVPFTIMLTCYFFIAQTIAGHFRKERIEG : . : :.. . .:::.... .::. :: :.:: : .: ... .. .. . NP_114 VCAFHYE-----SQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKP 210 220 230 240 250 260 240 250 260 270 280 290 pF1KB4 LRKRRRLLSIIVVLVVTFALCWMPYHLVKTLYMLGSL-LHWPCDFDLFLMNIFPYCTCIS . ...::...:. : . :.:... : .: .: . : . .. . .: ::. NP_114 --RNDDIFKIIMAIVLFFFFSWIPHQIFTFLDVLIQLGIIRDCRIADIVDTAMPITICIA 270 280 290 300 310 320 300 310 320 330 340 350 pF1KB4 YVNSCLNPFLYAFFDPRFRQACTSMLCCGQSRCAGTSHSSSGEKSASYS-----SGHSQG : :.::::..:.:. .:.. ..: . . :. :. .. :: :. .. NP_114 YFNNCLNPLFYGFLGKKFKRYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSTKK 330 340 350 360 370 380 360 370 380 pF1KB4 PGPNMGKGGEQMHEKSIPYSQETLVVD :.: NP_114 PAPCFEVE >>NP_114038 (OMIM: 106165,145500,267430) type-1 angioten (394 aa) initn: 616 init1: 375 opt: 652 Z-score: 637.3 bits: 126.7 E(85289): 9.3e-29 Smith-Waterman score: 652; 32.4% identity (66.4% similar) in 333 aa overlap (30-356:65-389) 10 20 30 40 50 pF1KB4 MEEGGDFDNYYGADNQSECEYTDWKSSGALIPAIYMLVFLLGTTGNGLVLWTVFRSSRE .::..: ..:..: ::.::. ... . NP_114 KMILNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKL 40 50 60 70 80 90 60 70 80 90 100 110 pF1KB4 KRRSADIFIASLAVADLTFVVTLPLWATYTYRDYDWPFGTFFCKLSSYLIFVNMYASVFC : :..:. .::.::: :..::::::.:: .: ::::...::..: . :.::::: NP_114 KT-VASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFL 100 110 120 130 140 150 120 130 140 150 160 170 pF1KB4 LTGLSFDRYLAIVRPVANARLRLRVSGAVATAVLWVLAALLAMPVMVLRTTGDLENTTKV :: ::.:::::::.:. . : . . :. ..:.::.: ..:... :.. .:::. . NP_114 LTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNIT 160 170 180 190 200 210 180 190 200 210 220 230 pF1KB4 QCYMDYSMVATVSSEWAWEVGLGVSSTTVGFVVPFTIMLTCYFFIAQTIAGHFRKERIEG : . : :.. . .:::.... .::. :: :.:: : .: ... .. .. . NP_114 VCAFHYE-----SQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKP 220 230 240 250 260 240 250 260 270 280 290 pF1KB4 LRKRRRLLSIIVVLVVTFALCWMPYHLVKTLYMLGSL-LHWPCDFDLFLMNIFPYCTCIS . ...::...:. : . :.:... : .: .: . : . .. . .: ::. NP_114 --RNDDIFKIIMAIVLFFFFSWIPHQIFTFLDVLIQLGIIRDCRIADIVDTAMPITICIA 270 280 290 300 310 320 300 310 320 330 340 350 pF1KB4 YVNSCLNPFLYAFFDPRFRQACTSMLCCGQSRCAGTSHSSSGEKSASYS-----SGHSQG : :.::::..:.:. .:.. ..: . . :. :. .. :: :. .. NP_114 YFNNCLNPLFYGFLGKKFKRYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSTKK 330 340 350 360 370 380 360 370 380 pF1KB4 PGPNMGKGGEQMHEKSIPYSQETLVVD :.: NP_114 PAPCFEVE 390 >>NP_004826 (OMIM: 106165,145500,267430) type-1 angioten (394 aa) initn: 616 init1: 375 opt: 652 Z-score: 637.3 bits: 126.7 E(85289): 9.3e-29 Smith-Waterman score: 652; 32.4% identity (66.4% similar) in 333 aa overlap (30-356:65-389) 10 20 30 40 50 pF1KB4 MEEGGDFDNYYGADNQSECEYTDWKSSGALIPAIYMLVFLLGTTGNGLVLWTVFRSSRE .::..: ..:..: ::.::. ... . NP_004 KMILNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKL 40 50 60 70 80 90 60 70 80 90 100 110 pF1KB4 KRRSADIFIASLAVADLTFVVTLPLWATYTYRDYDWPFGTFFCKLSSYLIFVNMYASVFC : :..:. .::.::: :..::::::.:: .: ::::...::..: . :.::::: NP_004 KT-VASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFL 100 110 120 130 140 150 120 130 140 150 160 170 pF1KB4 LTGLSFDRYLAIVRPVANARLRLRVSGAVATAVLWVLAALLAMPVMVLRTTGDLENTTKV :: ::.:::::::.:. . : . . :. ..:.::.: ..:... :.. .:::. . NP_004 LTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNIT 160 170 180 190 200 210 180 190 200 210 220 230 pF1KB4 QCYMDYSMVATVSSEWAWEVGLGVSSTTVGFVVPFTIMLTCYFFIAQTIAGHFRKERIEG : . : :.. . .:::.... .::. :: :.:: : .: ... .. .. . NP_004 VCAFHYE-----SQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKP 220 230 240 250 260 240 250 260 270 280 290 pF1KB4 LRKRRRLLSIIVVLVVTFALCWMPYHLVKTLYMLGSL-LHWPCDFDLFLMNIFPYCTCIS . ...::...:. : . :.:... : .: .: . : . .. . .: ::. NP_004 --RNDDIFKIIMAIVLFFFFSWIPHQIFTFLDVLIQLGIIRDCRIADIVDTAMPITICIA 270 280 290 300 310 320 300 310 320 330 340 350 pF1KB4 YVNSCLNPFLYAFFDPRFRQACTSMLCCGQSRCAGTSHSSSGEKSASYS-----SGHSQG : :.::::..:.:. .:.. ..: . . :. :. .. :: :. .. NP_004 YFNNCLNPLFYGFLGKKFKRYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSTKK 330 340 350 360 370 380 360 370 380 pF1KB4 PGPNMGKGGEQMHEKSIPYSQETLVVD :.: NP_004 PAPCFEVE 390 >>XP_011535835 (OMIM: 300034) PREDICTED: type-2 angioten (363 aa) initn: 469 init1: 252 opt: 585 Z-score: 573.6 bits: 114.8 E(85289): 3.3e-25 Smith-Waterman score: 585; 30.7% identity (62.7% similar) in 319 aa overlap (31-345:47-354) 10 20 30 40 50 60 pF1KB4 MEEGGDFDNYYGADNQSECEYTDWKSSGALIPAIYMLVFLLGTTGNGLVLWTVFRSSREK :: .:...:..: : .:. :.: .. XP_011 GLHFGLVNISGNNESTLNCSQKPSDKHLDAIPILYYIIFVIGFLVN-IVVVTLFCCQKGP 20 30 40 50 60 70 70 80 90 100 110 120 pF1KB4 RRSADIFIASLAVADLTFVVTLPLWATYTYRDYDWPFGTFFCKLSSYLIFVNMYASVFCL .. ..:.: .:::::: ...:::::::: ::: :: .::. . .. .::.::.: . XP_011 KKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFI 80 90 100 110 120 130 130 140 150 160 170 180 pF1KB4 TGLSFDRYLAIVRPVANARLRLRVSGAVATAVLWVLAALLAMPVMVLRTTGDLENTTKVQ : .: ::: ... : . : : ... . ..: .: : ..:.. .: . .: XP_011 TCMSVDRYQSVIYPFLSQR-RNPWQASYIVPLVWCMACLSSLPTFYFRDVRTIEYLGVNA 140 150 160 170 180 190 190 200 210 220 230 pF1KB4 CYMDYSMVATVSSEWA-WEVGLGVSSTTVGFVVPFTIMLTCYFFIAQTI--AGHFRKERI : : . ..: : .:... .. .::..:. .. :::: : . . .. . :.:: XP_011 CIMAFP-----PEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRI 200 210 220 230 240 240 250 260 270 280 290 pF1KB4 EGLRKRRRLLSIIVVLVVTFALCWMPYHLVKTLYMLGSL-LHWPCDFDLFLMNIFPYCTC : ..:.. ...:..: .::.:.:.. : :. . . :. . .:. XP_011 ----TRDQVLKMAAAVVLAFIICWLPFHVLTFLDALAWMGVINSCEVIAVIDLALPFAIL 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB4 ISYVNSCLNPFLYAFFDPRFRQACTSMLCCGQSRCAGTSHSSSGEKSASYSSGHSQGPGP ....:::.::::: : ::.: :.. . : .: : .::.: XP_011 LGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRESMSCRKSSSLREMETFVS 310 320 330 340 350 360 360 370 380 pF1KB4 NMGKGGEQMHEKSIPYSQETLVVD >>NP_000677 (OMIM: 300034) type-2 angiotensin II recepto (363 aa) initn: 469 init1: 252 opt: 585 Z-score: 573.6 bits: 114.8 E(85289): 3.3e-25 Smith-Waterman score: 585; 30.7% identity (62.7% similar) in 319 aa overlap (31-345:47-354) 10 20 30 40 50 60 pF1KB4 MEEGGDFDNYYGADNQSECEYTDWKSSGALIPAIYMLVFLLGTTGNGLVLWTVFRSSREK :: .:...:..: : .:. :.: .. NP_000 GLHFGLVNISGNNESTLNCSQKPSDKHLDAIPILYYIIFVIGFLVN-IVVVTLFCCQKGP 20 30 40 50 60 70 70 80 90 100 110 120 pF1KB4 RRSADIFIASLAVADLTFVVTLPLWATYTYRDYDWPFGTFFCKLSSYLIFVNMYASVFCL .. ..:.: .:::::: ...:::::::: ::: :: .::. . .. .::.::.: . NP_000 KKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFI 80 90 100 110 120 130 130 140 150 160 170 180 pF1KB4 TGLSFDRYLAIVRPVANARLRLRVSGAVATAVLWVLAALLAMPVMVLRTTGDLENTTKVQ : .: ::: ... : . : : ... . ..: .: : ..:.. .: . .: NP_000 TCMSVDRYQSVIYPFLSQR-RNPWQASYIVPLVWCMACLSSLPTFYFRDVRTIEYLGVNA 140 150 160 170 180 190 190 200 210 220 230 pF1KB4 CYMDYSMVATVSSEWA-WEVGLGVSSTTVGFVVPFTIMLTCYFFIAQTI--AGHFRKERI : : . ..: : .:... .. .::..:. .. :::: : . . .. . :.:: NP_000 CIMAFP-----PEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRI 200 210 220 230 240 240 250 260 270 280 290 pF1KB4 EGLRKRRRLLSIIVVLVVTFALCWMPYHLVKTLYMLGSL-LHWPCDFDLFLMNIFPYCTC : ..:.. ...:..: .::.:.:.. : :. . . :. . .:. NP_000 ----TRDQVLKMAAAVVLAFIICWLPFHVLTFLDALAWMGVINSCEVIAVIDLALPFAIL 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB4 ISYVNSCLNPFLYAFFDPRFRQACTSMLCCGQSRCAGTSHSSSGEKSASYSSGHSQGPGP ....:::.::::: : ::.: :.. . : .: : .::.: NP_000 LGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRESMSCRKSSSLREMETFVS 310 320 330 340 350 360 360 370 380 pF1KB4 NMGKGGEQMHEKSIPYSQETLVVD >>NP_004063 (OMIM: 602351) chemokine-like receptor 1 iso (371 aa) initn: 521 init1: 281 opt: 544 Z-score: 534.2 bits: 107.5 E(85289): 5.1e-23 Smith-Waterman score: 572; 34.7% identity (62.6% similar) in 329 aa overlap (34-348:44-356) 10 20 30 40 50 60 pF1KB4 GGDFDNYYGADNQSECEYTDWKSSGALIPAIYMLVFLLGTTGNGLVLWTVFRSSREKRRS .: .: .:: :::::. .. . . :. NP_004 DEYPDYLDSIVVLEDLSPLEARVTRIFLVVVYSIVCFLGILGNGLVI--IIATFKMKKTV 20 30 40 50 60 70 70 80 90 100 110 120 pF1KB4 ADIFIASLAVADLTFVVTLPLWATYTYRDYDWPFGTFFCKLSSYLIFVNMYASVFCLTGL ... .:::::. : : ::. ::. :: : ::: .::.:..:.. ::..::: :: . NP_004 NMVWFLNLAVADFLFNVFLPIHITYAAMDYHWVFGTAMCKISNFLLIHNMFTSVFLLTII 80 90 100 110 120 130 130 140 150 160 170 180 pF1KB4 SFDRYLAIVRPVANARLRLRVSGAVATAVLWVLAALLAMPVMVLRTTGDLENTTKVQCYM : :: .... :: . : . .: :.:::: .:. : .:.: :..:.. :..:. NP_004 SSDRCISVLLPVWSQNHRSVRLAYMACMVIWVLAFFLSSPSLVFRDTANLHG--KISCFN 140 150 160 170 180 190 200 210 220 230 pF1KB4 DYSMVATVSSEWAWE-----VGLG------VSSTTVGFVVPFTIMLTCYFFIAQTIAGHF ..:. . :: : . :: . :. ::.:: :. .::. ::. .. NP_004 NFSLSTPGSSSWPTHSQMDPVGYSRHMVVTVTRFLCGFLVPVLIITACYL----TIVCKL 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB4 RKERIEGLRKRRRLLSIIVVLVVTFALCWMPYHLVKTLYMLGSLLHWPCDFDLFLMNIFP ...: : : .. ..:::....:: ::: ::: :: .: : : ..: ... : NP_004 QRNR---LAKTKKPFKIIVTIIITFFLCWCPYH---TLNLL-ELHHTAMPGSVFSLGL-P 250 260 270 280 290 300 310 320 330 340 pF1KB4 YCTCISYVNSCLNPFLYAFFDPRFRQ---ACTSMLCCGQSRCAGTSHSSSGEKSASYSSG : .. .:::.::.::.:. :.. : : : . :. .: : : .. ...:: NP_004 LATALAIANSCMNPILYVFMGQDFKKFKVALFSRLVNALSEDTGHSSYPSHRSFTKMSSM 300 310 320 330 340 350 350 360 370 380 pF1KB4 HSQGPGPNMGKGGEQMHEKSIPYSQETLVVD NP_004 NERTSMNERETGML 360 370 >>XP_016874309 (OMIM: 602351) PREDICTED: chemokine-like (371 aa) initn: 521 init1: 281 opt: 544 Z-score: 534.2 bits: 107.5 E(85289): 5.1e-23 Smith-Waterman score: 572; 34.7% identity (62.6% similar) in 329 aa overlap (34-348:44-356) 10 20 30 40 50 60 pF1KB4 GGDFDNYYGADNQSECEYTDWKSSGALIPAIYMLVFLLGTTGNGLVLWTVFRSSREKRRS .: .: .:: :::::. .. . . :. XP_016 DEYPDYLDSIVVLEDLSPLEARVTRIFLVVVYSIVCFLGILGNGLVI--IIATFKMKKTV 20 30 40 50 60 70 70 80 90 100 110 120 pF1KB4 ADIFIASLAVADLTFVVTLPLWATYTYRDYDWPFGTFFCKLSSYLIFVNMYASVFCLTGL ... .:::::. : : ::. ::. :: : ::: .::.:..:.. ::..::: :: . XP_016 NMVWFLNLAVADFLFNVFLPIHITYAAMDYHWVFGTAMCKISNFLLIHNMFTSVFLLTII 80 90 100 110 120 130 130 140 150 160 170 180 pF1KB4 SFDRYLAIVRPVANARLRLRVSGAVATAVLWVLAALLAMPVMVLRTTGDLENTTKVQCYM : :: .... :: . : . .: :.:::: .:. : .:.: :..:.. :..:. XP_016 SSDRCISVLLPVWSQNHRSVRLAYMACMVIWVLAFFLSSPSLVFRDTANLHG--KISCFN 140 150 160 170 180 190 200 210 220 230 pF1KB4 DYSMVATVSSEWAWE-----VGLG------VSSTTVGFVVPFTIMLTCYFFIAQTIAGHF ..:. . :: : . :: . :. ::.:: :. .::. ::. .. XP_016 NFSLSTPGSSSWPTHSQMDPVGYSRHMVVTVTRFLCGFLVPVLIITACYL----TIVCKL 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB4 RKERIEGLRKRRRLLSIIVVLVVTFALCWMPYHLVKTLYMLGSLLHWPCDFDLFLMNIFP ...: : : .. ..:::....:: ::: ::: :: .: : : ..: ... : XP_016 QRNR---LAKTKKPFKIIVTIIITFFLCWCPYH---TLNLL-ELHHTAMPGSVFSLGL-P 250 260 270 280 290 300 310 320 330 340 pF1KB4 YCTCISYVNSCLNPFLYAFFDPRFRQ---ACTSMLCCGQSRCAGTSHSSSGEKSASYSSG : .. .:::.::.::.:. :.. : : : . :. .: : : .. ...:: XP_016 LATALAIANSCMNPILYVFMGQDFKKFKVALFSRLVNALSEDTGHSSYPSHRSFTKMSSM 300 310 320 330 340 350 350 360 370 380 pF1KB4 HSQGPGPNMGKGGEQMHEKSIPYSQETLVVD XP_016 NERTSMNERETGML 360 370 380 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 15:03:36 2016 done: Thu Nov 3 15:03:38 2016 Total Scan time: 7.470 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]