FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB4486, 1685 aa 1>>>pF1KB4486 1685 - 1685 aa - 1685 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 11.1152+/-0.00156; mu= 7.3094+/- 0.096 mean_var=774.3358+/-159.737, 0's: 0 Z-trim(113.7): 302 B-trim: 0 in 0/55 Lambda= 0.046090 statistics sampled from 14020 (14306) to 14020 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.664), E-opt: 0.2 (0.439), width: 16 Scan time: 4.840 The best scores are: opt bits E(32554) CCDS14543.1 COL4A5 gene_id:1287|Hs108|chrX (1685) 12890 874.6 0 CCDS35366.1 COL4A5 gene_id:1287|Hs108|chrX (1691) 12868 873.1 0 CCDS9511.1 COL4A1 gene_id:1282|Hs108|chr13 (1669) 7031 485.0 9.2e-136 CCDS42829.1 COL4A3 gene_id:1285|Hs108|chr2 (1670) 5533 385.4 8.9e-106 CCDS42828.1 COL4A4 gene_id:1286|Hs108|chr2 (1690) 3427 245.4 1.3e-63 CCDS6376.1 COL22A1 gene_id:169044|Hs108|chr8 (1626) 3185 229.2 8.8e-59 CCDS11561.1 COL1A1 gene_id:1277|Hs108|chr17 (1464) 3037 219.3 7.6e-56 CCDS76010.1 COL4A6 gene_id:1288|Hs108|chrX (1707) 3032 219.1 1e-55 CCDS41297.1 COL16A1 gene_id:1307|Hs108|chr1 (1604) 3017 218.1 2e-55 CCDS76008.1 COL4A6 gene_id:1288|Hs108|chrX (1633) 2896 210.0 5.4e-53 CCDS76009.1 COL4A6 gene_id:1288|Hs108|chrX (1666) 2896 210.0 5.4e-53 CCDS14542.1 COL4A6 gene_id:1288|Hs108|chrX (1690) 2896 210.0 5.4e-53 CCDS14541.1 COL4A6 gene_id:1288|Hs108|chrX (1691) 2896 210.0 5.4e-53 CCDS6802.1 COL27A1 gene_id:85301|Hs108|chr9 (1860) 2830 205.7 1.2e-51 CCDS41353.1 COL24A1 gene_id:255631|Hs108|chr1 (1714) 2738 199.6 8e-50 CCDS33350.1 COL5A2 gene_id:1290|Hs108|chr2 (1499) 2653 193.8 3.7e-48 CCDS2773.1 COL7A1 gene_id:1294|Hs108|chr3 (2944) 2595 190.4 7.7e-47 CCDS41907.1 COL4A2 gene_id:1284|Hs108|chr13 (1712) 2577 188.8 1.3e-46 CCDS2297.1 COL3A1 gene_id:1281|Hs108|chr2 (1466) 2216 164.7 2.1e-39 CCDS12222.1 COL5A3 gene_id:50509|Hs108|chr19 (1745) 2162 161.3 2.7e-38 CCDS8759.1 COL2A1 gene_id:1280|Hs108|chr12 (1418) 2085 156.0 8.5e-37 CCDS41778.1 COL2A1 gene_id:1280|Hs108|chr12 (1487) 2085 156.0 8.7e-37 CCDS4970.1 COL19A1 gene_id:1310|Hs108|chr6 (1142) 2045 153.2 4.8e-36 CCDS34682.1 COL1A2 gene_id:1278|Hs108|chr7 (1366) 2015 151.3 2.1e-35 CCDS75932.1 COL5A1 gene_id:1289|Hs108|chr9 (1838) 1959 147.8 3.2e-34 CCDS6982.1 COL5A1 gene_id:1289|Hs108|chr9 (1838) 1959 147.8 3.2e-34 CCDS780.2 COL11A1 gene_id:1301|Hs108|chr1 (1690) 1932 145.9 1.1e-33 CCDS53348.1 COL11A1 gene_id:1301|Hs108|chr1 (1767) 1932 146.0 1.1e-33 CCDS778.1 COL11A1 gene_id:1301|Hs108|chr1 (1806) 1932 146.0 1.1e-33 CCDS42971.1 COL18A1 gene_id:80781|Hs108|chr21 (1339) 1924 145.3 1.4e-33 CCDS42972.1 COL18A1 gene_id:80781|Hs108|chr21 (1519) 1924 145.3 1.5e-33 CCDS77643.1 COL18A1 gene_id:80781|Hs108|chr21 (1754) 1924 145.4 1.6e-33 CCDS43452.1 COL11A2 gene_id:1302|Hs108|chr6 (1650) 1882 142.6 1.1e-32 CCDS76649.1 COL4A1 gene_id:1282|Hs108|chr13 ( 519) 1716 130.8 1.2e-29 CCDS13505.1 COL9A3 gene_id:1299|Hs108|chr20 ( 684) 1694 129.5 3.9e-29 CCDS2934.1 COL8A1 gene_id:1295|Hs108|chr3 ( 744) 1629 125.2 8.2e-28 CCDS403.1 COL8A2 gene_id:1296|Hs108|chr1 ( 703) 1599 123.2 3.2e-27 CCDS72756.1 COL8A2 gene_id:1296|Hs108|chr1 ( 638) 1587 122.3 5.3e-27 CCDS44419.1 COL13A1 gene_id:1305|Hs108|chr10 ( 717) 1565 120.9 1.5e-26 CCDS44424.2 COL13A1 gene_id:1305|Hs108|chr10 ( 695) 1560 120.6 1.9e-26 CCDS44425.2 COL13A1 gene_id:1305|Hs108|chr10 ( 686) 1551 120.0 2.9e-26 CCDS5105.1 COL10A1 gene_id:1300|Hs108|chr6 ( 680) 1542 119.4 4.3e-26 CCDS44423.2 COL13A1 gene_id:1305|Hs108|chr10 ( 668) 1526 118.3 9e-26 CCDS44427.2 COL13A1 gene_id:1305|Hs108|chr10 ( 645) 1497 116.3 3.4e-25 CCDS43553.1 COL28A1 gene_id:340267|Hs108|chr7 (1125) 1436 112.7 7.4e-24 CCDS35081.1 COL15A1 gene_id:1306|Hs108|chr9 (1388) 1425 112.1 1.4e-23 CCDS44428.2 COL13A1 gene_id:1305|Hs108|chr10 ( 610) 1403 110.1 2.5e-23 CCDS58922.1 COL25A1 gene_id:84570|Hs108|chr4 ( 645) 1357 107.0 2.1e-22 CCDS7554.1 COL17A1 gene_id:1308|Hs108|chr10 (1497) 1359 107.8 3e-22 CCDS4436.1 COL23A1 gene_id:91522|Hs108|chr5 ( 540) 1253 100.0 2.3e-20 >>CCDS14543.1 COL4A5 gene_id:1287|Hs108|chrX (1685 aa) initn: 12890 init1: 12890 opt: 12890 Z-score: 4656.3 bits: 874.6 E(32554): 0 Smith-Waterman score: 12890; 100.0% identity (100.0% similar) in 1685 aa overlap (1-1685:1-1685) 10 20 30 40 50 60 pF1KB4 MKLRGVSLAAGLFLLALSLWGQPAEAAACYGCSPGSKCDCSGIKGEKGERGFPGLEGHPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 MKLRGVSLAAGLFLLALSLWGQPAEAAACYGCSPGSKCDCSGIKGEKGERGFPGLEGHPG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 LPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 LPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 IPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 IPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 IQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 IQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 PGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 PGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 GKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 GKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGN 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB4 IGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 IGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB4 PPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 PPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDT 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB4 CFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 CFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGF 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB4 PGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 PGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKG 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB4 ERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 ERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTIT 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB4 QPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 QPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGI 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB4 PGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 PGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFP 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB4 GPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 GPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHG 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB4 IPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 IPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGM 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB4 MGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 MGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLL 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB4 GSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 GSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLI 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB4 GPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 GPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPG 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB4 PKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 PKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPG 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KB4 NPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 NPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGL 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KB4 SGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 SGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPP 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KB4 GRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 GRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMK 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KB4 GDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 GDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGI 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KB4 PGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 PGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGP 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KB4 PGPDGLQGPPGPPGTSSVAHGFLITRHSQTTDAPQCPQGTLQVYEGFSLLYVQGNKRAHG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 PGPDGLQGPPGPPGTSSVAHGFLITRHSQTTDAPQCPQGTLQVYEGFSLLYVQGNKRAHG 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KB4 QDLGTAGSCLRRFSTMPFMFCNINNVCNFASRNDYSYWLSTPEPMPMSMQPLKGQSIQPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 QDLGTAGSCLRRFSTMPFMFCNINNVCNFASRNDYSYWLSTPEPMPMSMQPLKGQSIQPF 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KB4 ISRCAVCEAPAVVIAVHSQTIQIPHCPQGWDSLWIGYSFMMHTSAGAEGSGQALASPGSC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 ISRCAVCEAPAVVIAVHSQTIQIPHCPQGWDSLWIGYSFMMHTSAGAEGSGQALASPGSC 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KB4 LEEFRSAPFIECHGRGTCNYYANSYSFWLATVDVSDMFSKPQSETLKAGDLRTRISRCQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 LEEFRSAPFIECHGRGTCNYYANSYSFWLATVDVSDMFSKPQSETLKAGDLRTRISRCQV 1630 1640 1650 1660 1670 1680 pF1KB4 CMKRT ::::: CCDS14 CMKRT >>CCDS35366.1 COL4A5 gene_id:1287|Hs108|chrX (1691 aa) initn: 10244 init1: 10244 opt: 12868 Z-score: 4648.4 bits: 873.1 E(32554): 0 Smith-Waterman score: 12868; 99.6% identity (99.6% similar) in 1691 aa overlap (1-1685:1-1691) 10 20 30 40 50 60 pF1KB4 MKLRGVSLAAGLFLLALSLWGQPAEAAACYGCSPGSKCDCSGIKGEKGERGFPGLEGHPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS35 MKLRGVSLAAGLFLLALSLWGQPAEAAACYGCSPGSKCDCSGIKGEKGERGFPGLEGHPG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 LPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS35 LPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 IPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS35 IPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 IQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS35 IQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 PGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS35 PGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 GKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS35 GKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGN 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB4 IGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS35 IGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB4 PPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS35 PPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDT 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB4 CFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS35 CFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGF 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB4 PGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS35 PGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKG 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB4 ERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS35 ERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTIT 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB4 QPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS35 QPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGI 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB4 PGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS35 PGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFP 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB4 GPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS35 GPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHG 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB4 IPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS35 IPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGM 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB4 MGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS35 MGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLL 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB4 GSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS35 GSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLI 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB4 GPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS35 GPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPG 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB4 PKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS35 PKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPG 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KB4 NPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS35 NPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGL 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KB4 SGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS35 SGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPP 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 pF1KB4 GRPG------LPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRP :::: :::::::::::::::::::::::::::::::::::::::::::::::::: CCDS35 GRPGPTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRP 1270 1280 1290 1300 1310 1320 1320 1330 1340 1350 1360 1370 pF1KB4 GLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS35 GLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGD 1330 1340 1350 1360 1370 1380 1380 1390 1400 1410 1420 1430 pF1KB4 AGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS35 AGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGT 1390 1400 1410 1420 1430 1440 1440 1450 1460 1470 1480 1490 pF1KB4 RGLDGPPGPDGLQGPPGPPGTSSVAHGFLITRHSQTTDAPQCPQGTLQVYEGFSLLYVQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS35 RGLDGPPGPDGLQGPPGPPGTSSVAHGFLITRHSQTTDAPQCPQGTLQVYEGFSLLYVQG 1450 1460 1470 1480 1490 1500 1500 1510 1520 1530 1540 1550 pF1KB4 NKRAHGQDLGTAGSCLRRFSTMPFMFCNINNVCNFASRNDYSYWLSTPEPMPMSMQPLKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS35 NKRAHGQDLGTAGSCLRRFSTMPFMFCNINNVCNFASRNDYSYWLSTPEPMPMSMQPLKG 1510 1520 1530 1540 1550 1560 1560 1570 1580 1590 1600 1610 pF1KB4 QSIQPFISRCAVCEAPAVVIAVHSQTIQIPHCPQGWDSLWIGYSFMMHTSAGAEGSGQAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS35 QSIQPFISRCAVCEAPAVVIAVHSQTIQIPHCPQGWDSLWIGYSFMMHTSAGAEGSGQAL 1570 1580 1590 1600 1610 1620 1620 1630 1640 1650 1660 1670 pF1KB4 ASPGSCLEEFRSAPFIECHGRGTCNYYANSYSFWLATVDVSDMFSKPQSETLKAGDLRTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS35 ASPGSCLEEFRSAPFIECHGRGTCNYYANSYSFWLATVDVSDMFSKPQSETLKAGDLRTR 1630 1640 1650 1660 1670 1680 1680 pF1KB4 ISRCQVCMKRT ::::::::::: CCDS35 ISRCQVCMKRT 1690 >>CCDS9511.1 COL4A1 gene_id:1282|Hs108|chr13 (1669 aa) initn: 5726 init1: 3511 opt: 7031 Z-score: 2550.8 bits: 485.0 E(32554): 9.2e-136 Smith-Waterman score: 7535; 61.4% identity (73.7% similar) in 1704 aa overlap (5-1685:2-1669) 10 20 30 40 50 pF1KB4 MKLRGVSLAAGLFLL--ALSLWGQPAEAAACYGCSPGS---KCDCSGIKGEKGERGFPGL : :.. :.:: :: : . ..::: ::. :: :::: :.::.:::::.::: CCDS95 MGPRLSVWLLLLPAALLLHEEHSRAAAKGGCA-GSGCGKCDCHGVKGQKGERGLPGL 10 20 30 40 50 60 70 80 90 100 110 pF1KB4 EGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGA .: :.::. ::::: :: ::::: : :: :: :: ::::: :.::.:::::.::.:: CCDS95 QGVIGFPGMQGPEGPQGPPGQKGDTGEPGLPGTKGTRGPPGASGYPGNPGLPGIPGQDGP 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB4 PGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGP--KGNP ::: ::::::::::::: : ::.::. : :::::.:::::.:: : .. .:: ::. CCDS95 PGPPGIPGCNGTKGERGPLGPPGLPGFAGNPGPPGLPGMKGDPGEI-LGHVPGMLLKGER 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB4 GYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQG :.:: :: : :: :. ::.:::: : ::::::: :: ::.:::.::::::.::.:: CCDS95 GFPGIPGTPGPPGLPGLQGPVGPPGFTGPPGPPGPPGPPGEKGQMGLSFQGPKGDKGDQG 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB4 LQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGE ..:::: ::: . : .::: . :..: : ::..: :: ::::: :. CCDS95 VSGPPGVPGQAQVQ--------EKGDFATKGEKGQKGEPGFQGMPGV-----GEKGEPGK 240 250 260 270 280 300 310 320 330 340 350 pF1KB4 PGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGI :: ::::::::..:. : ::.::.::::: ::.: .:.::..:::::::.:: ::: CCDS95 PGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGRQGPQGEKGEAGPPGPPGIVI---GTG- 290 300 310 320 330 360 370 380 390 400 410 pF1KB4 TIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGP .::::. : :: :: .:: : :. : :: ::::: : : : ::::::::.:::.: CCDS95 PLGEKGERGYPGTPGPRGEPGPKGFPGLPGQPGPPGLPVPGQAGAPGFPGERGEKGDRGF 340 350 360 370 380 390 420 430 440 450 460 470 pF1KB4 PGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPG---PPGSPGDKGLQGE :: :.::: : :: :: :: ::::: : . :.::::: ::: ::. :. :: CCDS95 PGTSLPGPSGRDGLPGPPGSPGPPGQPGYTNGIVE--CQPGPPGDQGPPGIPGQPGFIGE 400 410 420 430 440 450 480 490 500 510 520 530 pF1KB4 QGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPG : ::.::..:. : : :::: : :::: .::::: : ::. : : :. : CCDS95 IGEKGQKGESCLICDIDGYRGPPG-P-----QGPPGEIGFPGQPGAKGDRGLPGRDGVAG 460 470 480 490 500 510 540 550 560 570 580 pF1KB4 IPGAPGAPGF---PGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLP .:: :.::. ::.:::::.. .:::::. : :: ::.:: :.::.:: :::: CCDS95 VPGPQGTPGLIGQPGAKGEPGEFYFDLRLKGDKGDPGFPGQPGMPGRAGSPGRDGHPGLP 520 530 540 550 560 570 590 600 610 620 630 640 pF1KB4 GPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPG :::: ::.. .::::::::. :.:: :. :: ::::.:: ::.:.:: : :.::.:: CCDS95 GPKGSPGSVGLKGERGPPGGVGFPGSRGDTGPPGPPGYGPAGPIGDKGQAGFPGGPGSPG 580 590 600 610 620 630 650 660 670 680 690 700 pF1KB4 IPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIG .:::::.::. . :: :: : :: : : :: :.:: :: ::.:: :: : :::: CCDS95 LPGPKGEPGKIVPLPGPPGAEGLPGSPGFPGPQGDRGFPGTPGRPGLPGEKGAVGQPGIG 640 650 660 670 680 690 710 720 730 740 750 760 pF1KB4 LPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGF .:::::::: :.:: : :::::: :..: :: :: : ::::: .::: : :::::. CCDS95 FPGPPGPKGVDGLPGDMGPPGTPGRPGFNGLPGNPGVQGQKGEPGVGLPGLKGLPGLPGI 700 710 720 730 740 750 770 780 790 800 810 820 pF1KB4 KGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPP :. : ::. : :: :: : : :: : .:. :: : :: .: ::.:::: : ::: CCDS95 PGTPGEKGSIGVPGVPGEHGAIGPPGLQGIRGEPGPPGLPGSVGSPGVPGIGPPGARGPP 760 770 780 790 800 810 830 840 850 860 870 880 pF1KB4 GIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAG : :: : : :: :::: :: ::::.::: :..:. :.:: : : :: :: : : CCDS95 GGQGPPGLSGPPGIKGEKGFPGFPGLDMPGPKGDKGAQGLPGITGQSGLPGLPGQQGAPG 820 830 840 850 860 870 890 900 910 920 930 940 pF1KB4 ASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPG ::::.:::::.:: :: :: : : :.:: ::: :. :. : : : ::.::. : CCDS95 IPGFPGSKGEMGVMGTPGQPGSPGPVGAPGLPGEKGDHGFPGSSGPRGDPGLKGDKGDVG 880 890 900 910 920 930 950 960 970 980 990 1000 pF1KB4 LPGPPGPMDPNLLGS-KGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPG ::: :: :: .:: ::.::. : : : : :: .: :: :: :: .:: : :: :: CCDS95 LPGKPGSMDKVDMGSMKGQKGDQGEKGQIGPIGEKGSRGDPGTPGVPGKDGQAGQPGQPG 940 950 960 970 980 990 1010 1020 1030 1040 1050 1060 pF1KB4 PKGNPGLPGQPGLIGPPGLKGTIGDMGFPG-P--QGVEGPPGPSGVPGQPGSPGLPGQKG :::.::. : :: : :: ::..: ::.:: : .:: : :::.: :: ::. : :.:: CCDS95 PKGDPGISGTPGAPGLPGPKGSVGGMGLPGTPGEKGVPGIPGPQGSPGLPGDKGAKGEKG 1000 1010 1020 1030 1040 1050 1070 1080 1090 1100 1110 1120 pF1KB4 DKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGF . : ::: :.::: : ::. :. :.::.:: :: :. :.::.::.:: ::.:: :. CCDS95 QAGPPGI---GIPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIPGMPGSPGLKGSPGSVGY 1060 1070 1080 1090 1100 1130 1140 1150 1160 1170 1180 pF1KB4 PGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGE ::.:: :: :: .: :: :.:: : .: : :: :: :.::.::.::::: ::.::: CCDS95 PGSPGLPGEKGDKGLPGLDGIPGVKGEAGLPGTPGPTGPAGQKGEPGSDGIPGSAGEKGE 1110 1120 1130 1140 1150 1160 1190 1200 1210 1220 1230 1240 pF1KB4 PGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSP :: :: : :: :: : .:.::. :.::. :.::.:: ::: :: : :: :: :: :::: CCDS95 PGLPGRGFPGFPGAKGDKGSKGEVGFPGLAGSPGIPGSKGEQGFMGPPGPQGQPGLPGSP 1170 1180 1190 1200 1210 1220 1250 1260 1270 1280 1290 1300 pF1KB4 GPALEGPKGNPGPQGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQG : : :::::. :::: :: :::::: ::::::: :.::.::::: :: ::.:: ::: : CCDS95 GHATEGPKGDRGPQGQPGLPGLPGPMGPPGLPGIDGVKGDKGNPGWPGAPGVPGPKGDPG 1230 1240 1250 1260 1270 1280 1310 1320 1330 1340 1350 1360 pF1KB4 PPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKG-PS--GVPGSAGPEGEPGLIGPPGPPG :. : : ::..: ::: : :::::: : :: :. :. :. : .: :: : ::::: CCDS95 FQGMPGIGGSPGITGSKGDMGPPGVPGFQGPKGLPGLQGIKGDQGDQGVPGAKGLPGPPG 1290 1300 1310 1320 1330 1340 1370 1380 1390 1400 1410 pF1KB4 LPGPSGQSIIIKGDAGPPGIPGQPGLKGL---PGPQGPQGLPGPTGPPGDPGRNGLPGFD ::: ::::. : :: : :::::: :::.: ::. : .: :: : :.:::: CCDS95 PPGPYD---IIKGEPGLPGPEGPPGLKGLQGLPGPKGQQGVTGLVGIPGPP---GIPGFD 1350 1360 1370 1380 1390 1400 1420 1430 1440 1450 1460 1470 pF1KB4 GAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPGTSSVAHGFLITRHSQTTDAPQCP :: :.::. : : : ::. :::::::: : ::::: :: ::::.:::::: : :::: CCDS95 GAPGQKGEMGPAGPTGPRGFPGPPGPDGLPGSMGPPGTPSVDHGFLVTRHSQTIDDPQCP 1410 1420 1430 1440 1450 1460 1480 1490 1500 1510 1520 1530 pF1KB4 QGTLQVYEGFSLLYVQGNKRAHGQDLGTAGSCLRRFSTMPFMFCNINNVCNFASRNDYSY .:: .:.:.::::::::.:::::::::::::::.::::::.:::::::::::::::::: CCDS95 SGTKILYHGYSLLYVQGNERAHGQDLGTAGSCLRKFSTMPFLFCNINNVCNFASRNDYSY 1470 1480 1490 1500 1510 1520 1540 1550 1560 1570 1580 1590 pF1KB4 WLSTPEPMPMSMQPLKGQSIQPFISRCAVCEAPAVVIAVHSQTIQIPHCPQGWDSLWIGY :::::::::::: :. :..:.:::::::::::::.:.:::::::::: ::.::.:::::: CCDS95 WLSTPEPMPMSMAPITGENIRPFISRCAVCEAPAMVMAVHSQTIQIPPCPSGWSSLWIGY 1530 1540 1550 1560 1570 1580 1600 1610 1620 1630 1640 1650 pF1KB4 SFMMHTSAGAEGSGQALASPGSCLEEFRSAPFIECHGRGTCNYYANSYSFWLATVDVSDM ::.:::::::::::::::::::::::::::::::::::::::::::.:::::::.. :.: CCDS95 SFVMHTSAGAEGSGQALASPGSCLEEFRSAPFIECHGRGTCNYYANAYSFWLATIERSEM 1590 1600 1610 1620 1630 1640 1660 1670 1680 pF1KB4 FSKPQSETLKAGDLRTRISRCQVCMKRT :.:: :::::.:::..:::::::.:: CCDS95 FKKPTPSTLKAGELRTHVSRCQVCMRRT 1650 1660 >>CCDS42829.1 COL4A3 gene_id:1285|Hs108|chr2 (1670 aa) initn: 5578 init1: 1874 opt: 5533 Z-score: 2012.5 bits: 385.4 E(32554): 8.9e-106 Smith-Waterman score: 6498; 55.1% identity (68.0% similar) in 1682 aa overlap (12-1684:14-1668) 10 20 30 40 50 pF1KB4 MKLRGVSLAAGLFLLALSLWGQPAEAAACYGCSPGSKCDCSGIKGEKGERGFPGLEGH : :: . : . :: . .: :. ..: :.: ::::::.:::: : CCDS42 MSARTAPRPQVLLLPLLLVLLAAAPAASKGCV-CKDKGQCFCDGAKGEKGEKGFPGPPGS 10 20 30 40 50 60 70 80 90 100 110 pF1KB4 PGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGP :: :: :::: :::.: :: :.:: : ::.:: ::::: :.::::: ::. : : CCDS42 PGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGL 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB4 QGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGP :.:::.:.:::.:::: :: : : :: :. :.:: :.. : . ::.:: :: CCDS42 VGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDA-KGDPGLPGA 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB4 PGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPP :: :::::: :.:::.:::::::..: :: : ::::.:: : :::.: .:: ::: CCDS42 PGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPP 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB4 GPPGQ-ISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKR :::: : : . ::..: : : ::::: : :: : .::: :.:: . CCDS42 GPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYG--SEKGAPGDPGLQ 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB4 GKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGE ::::::: : :: :. :. :.:: :.:: :::::: :::: : : : : CCDS42 GKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRG---PTEYYD-TYQE 300 310 320 330 340 350 360 370 380 390 400 410 pF1KB4 KGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGIS ::. : :: :: .: :: : .::::.:: ::.. : : ::.:: .:.::..: :: . CCDS42 KGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKD 360 370 380 390 400 410 420 430 440 450 460 470 pF1KB4 IPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPG---DKGLQGEQGVK : :: : :.::::: ::: :: :.: . . :::: : :: . :. : .: : CCDS42 AMGTPGSPGCAGSPGLPGSPGPPGP---PGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPK 420 430 440 450 460 480 490 500 510 520 530 pF1KB4 GDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGA :. : : .: : :::: :::::: : : : : : ::. :. : ::::.:: CCDS42 GEPGLLCTQC--PYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGF 470 480 490 500 510 520 540 550 560 570 580 590 pF1KB4 PGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPG ::: : :: ::: :. : :. : :. : : :: :: : :: :. :::::::: . CCDS42 PGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELA 530 540 550 560 570 580 600 610 620 630 640 650 pF1KB4 GITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGD ::..::::.:: :: :: :: ::::.:: : : .: ::: : :: :: ::.:. CCDS42 LSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGE 590 600 610 620 630 640 660 670 680 690 700 710 pF1KB4 PGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGP . . :: :: :: ::. : : :: :: :. : ::.:: :::::::::.:::::: CCDS42 LSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGP 650 660 670 680 690 700 720 730 740 750 760 770 pF1KB4 KGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPK :: :.:: :. : ::..: : :: ::.:: ::::. :.:: :: ::.:: .: : . CCDS42 KGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEH 710 720 730 740 750 760 780 790 800 810 820 830 pF1KB4 GDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIG :. :.:: :: :: : .:: ::.:: : : :: .:::: : .: : ::. : : CCDS42 GEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKG 770 780 790 800 810 820 840 850 860 870 880 890 pF1KB4 QPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGT : : .: : ::::: :::: : ::: ::::::: : .:: :. : ::. : : :: CCDS42 QQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGE 830 840 850 860 870 880 900 910 920 930 940 950 pF1KB4 KGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGP : .:::: :: :: : :: :.:: .:. :. ::. : : :.::: : : ::: CCDS42 DGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGI---PGVKGQRGTPGAKGEQGDKGNPGP 890 900 910 920 930 940 960 970 980 990 1000 1010 pF1KB4 MDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLP . . . :.:::::: :. : : :: .:.:: :: ::.: :: :::::.:. : CCDS42 SEISHV--IGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGST 950 960 970 980 990 1000 1020 1030 1040 1050 1060 1070 pF1KB4 GQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIG :.:: : :. :..:.::.:: .: .: : : :.:: ::. : .::::.:: : CCDS42 GNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGT 1010 1020 1030 1040 1050 1060 1080 1090 1100 1110 1120 1130 pF1KB4 LPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKG :: ::: :.:::: :. : :: .:.:: :: : : .: :: :: :: :: :::.: CCDS42 RPGPPGPTGDPGLP---GDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHG 1070 1080 1090 1100 1110 1140 1150 1160 1170 1180 1190 pF1KB4 ISGPPGNPGLPGEPG---PVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGN : : :: : :: : : : ::.::: : .: :.::::::::.::: : . CCDS42 DLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLR-AP 1120 1130 1140 1150 1160 1170 1200 1210 1220 1230 1240 1250 pF1KB4 PGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPK ::: : :: .: ::: : ::.:: :: : :. : .: :..: ::::: :: . : CCDS42 PGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQT 1180 1190 1200 1210 1220 1230 1260 1270 1280 1290 1300 1310 pF1KB4 GNPGPQGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNP :: :: : : :: ::: :::: ::::.::. :.:: : :: ::.:::: : : CCDS42 GNRGPPGSRGSPGAPGPPGPPG-SHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAP 1240 1250 1260 1270 1280 1290 1320 1330 1340 1350 1360 1370 pF1KB4 GRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIII : ::: : .::::. : :::.:: .: :: : : :: ::: ::::. : : :: CCDS42 GTPGLPGPRGDPGFQG---FPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKII 1300 1310 1320 1330 1340 1350 1380 1390 1400 1410 1420 pF1KB4 K--GDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLP . :. :::: ::.::..: ::: :: : :: :: : ::..: :: : .:.::. : CCDS42 SLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSK 1360 1370 1380 1390 1400 1410 1430 1440 1450 1460 1470 1480 pF1KB4 GQPGTRGLDGPPGPDGLQGPPGPPGTSSVAHGFLITRHSQTTDAPQCPQGTLQVYEGFSL :.:: : :: :: : .: : :.: .. .::..::::::: :.::.::. .: :::. CCDS42 GEPGPAGSDGLPGLKGKRGDSGSPATWTT-RGFVFTRHSQTTAIPSCPEGTVPLYSGFSF 1420 1430 1440 1450 1460 1470 1490 1500 1510 1520 1530 1540 pF1KB4 LYVQGNKRAHGQDLGTAGSCLRRFSTMPFMFCNINNVCNFASRNDYSYWLSTPEPMPMSM :.::::.::::::::: ::::.::.::::.:::.:.::::::::::::::::: :::.: CCDS42 LFVQGNQRAHGQDLGTLGSCLQRFTTMPFLFCNVNDVCNFASRNDYSYWLSTPALMPMNM 1480 1490 1500 1510 1520 1530 1550 1560 1570 1580 1590 1600 pF1KB4 QPLKGQSIQPFISRCAVCEAPAVVIAVHSQTIQIPHCPQGWDSLWIGYSFMMHTSAGAEG :. :....:.::::.:::.::..::::::: .:: ::.:: ::: :.::.: ::::.:: CCDS42 APITGRALEPYISRCTVCEGPAIAIAVHSQTTDIPPCPHGWISLWKGFSFIMFTSAGSEG 1540 1550 1560 1570 1580 1590 1610 1620 1630 1640 1650 1660 pF1KB4 SGQALASPGSCLEEFRSAPFIECHGRGTCNYYANSYSFWLATVDVSDMFSKPQSETLKAG .:::::::::::::::..::.:::::::::::.::::::::... :: :: :.::: CCDS42 TGQALASPGSCLEEFRASPFLECHGRGTCNYYSNSYSFWLASLNPERMFRKPIPSTVKAG 1600 1610 1620 1630 1640 1650 1670 1680 pF1KB4 DLRTRISRCQVCMKRT .:. :::::::::. CCDS42 ELEKIISRCQVCMKKRH 1660 1670 >>CCDS42828.1 COL4A4 gene_id:1286|Hs108|chr2 (1690 aa) initn: 1600 init1: 856 opt: 3427 Z-score: 1255.6 bits: 245.4 E(32554): 1.3e-63 Smith-Waterman score: 5113; 50.5% identity (63.4% similar) in 1580 aa overlap (163-1685:182-1690) 140 150 160 170 180 190 pF1KB4 FPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPG .... : .:.:: :: :: : ::. : CCDS42 GGRGALGPGGPLGHPGEKGEKGNSVFILGAVKGIQGDRGDPGLPGLPGSWGAGGPA---G 160 170 180 190 200 200 210 220 230 240 250 pF1KB4 PIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPID : : :: :::.:::: :: :: ::: :.. .: :. :: : :: ::: . .: : CCDS42 PTGYPGEPGLVGPPGQPGRPGLKGNPGVGVKGQMGDPGEVGQQGSPGPTLLV----EPPD 210 220 230 240 250 260 260 270 280 290 300 pF1KB4 VEFQKGDQGL---PGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQP . ::..:. :: : ::::: .: : : ::::: : :: :: ::. :.: CCDS42 FCLYKGEKGIKGIPGMVGLPGPPGRKGESGI--GAKGEKGIPGFPGPRGDPGS---YGSP 270 280 290 300 310 310 320 330 340 350 360 pF1KB4 GIPGLPGDPGYPGEPGRDGEKGQKGDTGP---PGPPGLVIPRPGTGITIGEKGNIGLPGL :.::: :. : :.:: : : ::: : :::::... : . :: : ::. CCDS42 GFPGLKGELGLVGDPGLFGLIGPKGDPGNRGHPGPPGVLVTPP-----LPLKGPPGDPGF 320 330 340 350 360 370 370 380 390 400 410 420 pF1KB4 PGEKGERGFPGIQGPPGLPGPPG---AAVMGPPGPPGFPGERGQKGDEGPPGI--SIPGP ::. :: : : ::::: : :: :...::::: :::: : :. : :: : :: CCDS42 PGRYGETGDVGPPGPPGLLGRPGEACAGMIGPPGPQGFPGLPGLPGEAGIPGRPDSAPGK 380 390 400 410 420 430 430 440 450 460 470 480 pF1KB4 PGLDGQPGAPGLPGPPGPAGPHIPPSDEI-CEPGPPGPPGSPGDKGLQGEQGVKGDKGDT :: .::.::::: :: : .: :. : : : ::: : : : : .: ::.::. CCDS42 PG---KPGSPGLPGAPGLQG--LPGSSVIYCSVGNPGPQGIKGKVGPPGGRGPKGEKGNE 440 450 460 470 480 490 500 510 520 530 540 pF1KB4 CFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGF . : :::: ::::: : :.::.:: : ::. : : .: ::.:: :: : CCDS42 GLCACEPGPMGPPGPPGLPGRQGSKGDLGLPGWLGTKGDPGPPGAEGPPGLPGKHGASGP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB4 PGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKG ::.:: ::... .:: ::: : : ::.:: ::. :.:: : : : :: CCDS42 PGNKGAKGDMVV-SRVKGHKGERGPDGPPGFPGQPGSHGRDGHAGEKGDPGPPGD----H 550 560 570 580 590 600 610 620 630 640 650 pF1KB4 ERGPPGNPGLPGL---PGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQ : . ::. :.:: ::. ::.::::.: ::: ::.: :: :.:: : : ::. :. CCDS42 EDATPGGKGFPGPLGPPGKAGPVGPPGLGFPGPPGERGHPGVPGHPGVRGPDGLKGQKGD 610 620 630 640 650 660 660 670 680 690 700 710 pF1KB4 TIT-QPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIG-LPGPPGPK ::. . :: : :: :: : : :: : ::: : : ::.:: :: . .::::: . CCDS42 TISCNVTYPGRHGPPGFDGPPGPKGFPGPQGAPGLSGSDGHKGRPGTPGTAEIPGPPGFR 670 680 690 700 710 720 720 730 740 750 760 770 pF1KB4 GFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPG---FALPGPPGPPGLPGFKGALG : : :: : :. . .: :::: :: : :: :: :. :::: :: : : : CCDS42 GDMGDPGFGGEKGS-SPVGPPGPPGSPGVNGQKGIPGDPAFGHLGPPGKRGLSGVPGIKG 730 740 750 760 770 780 780 790 800 810 820 830 pF1KB4 PKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGP :.:: : :: :: : :. :: :::: : : :: :::: .: :: :: :: CCDS42 PRGDPGCPGAEGPAGIPGFLGLKGPKGREGHAGFPGVPGPPGHS--CERGAPGIPGQPGL 790 800 810 820 830 840 840 850 860 870 880 890 pF1KB4 IGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFP : :: : :: ::.:: : ::: : .: ::.:: :: :::: ::.:: : .:.: CCDS42 PGYPGSPGAPGGKGQPGDVG--PPGPAGMKGLPGLPGRPGAHGPPGLPGIPGPFGDDGLP 850 860 870 880 890 900 910 920 930 940 pF1KB4 GT---KGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLP : :: :. : :: :: : :: : :: ::. : .:. :::: : .:.:: : : CCDS42 GPPGPKGPRGLPGFPGFPGERGKPGAEGCPGAKGEPGEKGMSGLPGDRGLRGAKGAIGPP 900 910 920 930 940 950 950 960 970 980 990 1000 pF1KB4 GPPGPMDPNLLGSKGEKGEPGLPG---IPGVSGPKGYQGLPGDPGQPGLSGQPGLP-GPP : : : ....:: :::: :: .:: : :: :. : :.:: : ::. : : CCDS42 GDEGEM--AIISQKGTPGEPGPPGDDGFPGERGDKGTPGMQGRRGEPGRYGPPGFHRGEP 960 970 980 990 1000 1010 1010 1020 1030 1040 1050 1060 pF1KB4 GPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDK : ::.:: :: :: : ::.: :: :.:: :: : ::: :: : : : ::.: CCDS42 GEKGQPGPPGPPGPPGSTGLRGFIGFPGLPGDQGEPGSPGP---PGFSGIDGARGPKGNK 1020 1030 1040 1050 1060 1070 1070 1080 1090 1100 1110 1120 pF1KB4 GDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPG :::. : .: : :::::::: :: ::. : .: . ::::. : :. :.:: :: : CCDS42 GDPA-SHFG-P--PGPKGEPGSPGCPGHFGASG---EQGLPGIQGPRGSPGRPGPPGSSG 1080 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 pF1KB4 TPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKG---KPGQDGIPGPAGQKG :: :: .:. : :.:: :.::: : : :: ::::: :: .:: .:. : :::: CCDS42 PPGCPGDHGMPGLRGQPGEMGDPGPRGLQGDPGIPGPPGIKGPSGSPGLNGLHGLKGQKG 1130 1140 1150 1160 1170 1180 1190 1200 1210 1220 1230 pF1KB4 EPGQPGF---GNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGP : :. : ::: :.:::.:..:: : ::: .: :::.:. : : :: .::::: CCDS42 TKGASGLHDVGPPGPVGIPGLKGERGDPGSPGI--SP--PGPRGKKGPPGPPGSSGPPGP 1190 1200 1210 1220 1230 1240 1240 1250 1260 1270 1280 1290 pF1KB4 PGSPGPALEGPKGNPGPQGPPGRPGLPGPEGPPGLPGNGGIKGE----KGNPGQPGLPGL :. : : :: : : :::: : :::.:: : :: :. : .:.::. :::: CCDS42 AGATGRA---PKDIPDP-GPPGDQGPPGPDGPRGAPGPPGLPGSVDLLRGEPGDCGLPGP 1250 1260 1270 1280 1290 1300 1310 1320 1330 1340 1350 pF1KB4 PGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGP :: : :::: .: :: : .:.:: : :::: .:: : :: : :: :: :: CCDS42 PGPPGPPGPPGYKGFPGCDGKDGQKG-P-----VGFPGPQGPHGFPG---PPGEKGLPGP 1300 1310 1320 1330 1340 1350 1360 1370 1380 1390 1400 pF1KB4 PG---PPGLPGPSGQSIIIKGDAGPPG-------IPGQPGLKGLPGPQGPQGLPGPTGPP :: : ::::: .:. :::. ::: :: :. ::.: .:::: :: CCDS42 PGRKGPTGLPGP-------RGEPGPPADVDDCPRIPGLPGAPGMRGPEGAMGLPGMRGPS 1360 1370 1380 1390 1400 1410 1420 1430 1440 1450 1460 pF1KB4 GDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGP---PGTSSVAHG- : :: .: ::.:: : : :: :: :: .: : : : ::::: :: .. . : CCDS42 G-PGCKGEPGLDGRRGVDGVPGSPGPPGRKGDTGEDGYPGGPGPPGPIGDPGPKGFGPGY 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 1510 pF1KB4 ---FLITRHSQTTDAPQCPQGTLQVYEGFSLLYVQGNKRAHGQDLGTAGSCLRRFSTMPF ::.. :::: . : :: : ... :.::::..:...::.:::: ::::: :::.:: CCDS42 LGGFLLVLHSQTDQEPTCPLGMPRLWTGYSLLYLEGQEKAHNQDLGLAGSCLPVFSTLPF 1470 1480 1490 1500 1510 1520 1520 1530 1540 1550 1560 1570 pF1KB4 MFCNINNVCNFASRNDYSYWLSTPEPMPMSMQPLKGQSIQPFISRCAVCEAPAVVIAVHS .:::..::..:.::: ::::.. :.:: .::. ..:.:..:::::::::: ..:::: CCDS42 AYCNIHQVCHYAQRNDRSYWLASAAPLPM--MPLSEEAIRPYVSRCAVCEAPAQAVAVHS 1530 1540 1550 1560 1570 1580 1580 1590 1600 1610 1620 1630 pF1KB4 QTIQIPHCPQGWDSLWIGYSFMMHTSAGAEGSGQALASPGSCLEEFRSAPFIECHGR-GT : .:: ::: : ::::::::.:::.:: .:.:::: :::::::.::.:::.::.:: :: CCDS42 QDQSIPPCPQTWRSLWIGYSFLMHTGAGDQGGGQALMSPGSCLEDFRAAPFLECQGRQGT 1590 1600 1610 1620 1630 1640 1640 1650 1660 1670 1680 pF1KB4 CNYYANSYSFWLATVDVSDMFSK-PQSETLKAGDL-RTRISRCQVCMKRT :...::.:::::.:: .. .::. : .::: .. : .:::::::.: . CCDS42 CHFFANKYSFWLTTVKADLQFSSAPAPDTLKESQAQRQKISRCQVCVKYS 1650 1660 1670 1680 1690 >>CCDS6376.1 COL22A1 gene_id:169044|Hs108|chr8 (1626 aa) initn: 800 init1: 800 opt: 3185 Z-score: 1168.8 bits: 229.2 E(32554): 8.8e-59 Smith-Waterman score: 3563; 45.5% identity (58.6% similar) in 1301 aa overlap (134-1382:439-1625) 110 120 130 140 150 160 pF1KB4 PGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGS--- :..: . : :: : ::: CCDS63 YDSVPIDFDLQRIVIYCDSRHAELETCCDIPSGPCQVTVVTEPPPPPPPQRPPTPGSEQI 410 420 430 440 450 460 170 180 190 200 210 pF1KB4 ----IIMSSLP-GPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPK : : : : ::. : :: .::::: : : ::: : :: : : :. :: CCDS63 GFLKTINCSCPAGEKGEMGVAGP---MGLPGPKGDIGAIGPVGAPGPKGEKGDVGI-GPF 470 480 490 500 510 520 220 230 240 250 260 270 pF1KB4 GNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGD---RGPPGPP : :: ::::: :: :::: :. . . .: .. :. ::::. ::: ::: CCDS63 G------QGEKGEKGSLGLPGPPGRDGSKGMRGEPGEL----GEPGLPGEVGMRGPQGPP 530 540 550 560 570 280 290 300 310 320 330 pF1KB4 GIRGPPGPPG--GEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEK :. ::::: : : .::.:: : ::. :. : .: :: :: :. : :: : : . CCDS63 GL---PGPPGRVGAPGLQGERGEKGTRGEKGERGLDGFPGKPGDTGQQGRPGPSGVAGPQ 580 590 600 610 620 630 340 350 360 370 380 390 pF1KB4 GQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGA :.:::.:: ::::. ::. .. ..: : : :: .:..: :: ::: :: : CCDS63 GEKGDVGPAGPPGV----PGS--VVQQEGLKGEQGAPGPRGHQGAPG---PPGARGPIGP 640 650 660 670 680 400 410 420 430 440 pF1KB4 AVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAG-PHIPPSDE : ::::. : ::.::: :::: ::: ::.: :: ::.::::::.: : .: : CCDS63 E--GRDGPPGLQGLRGKKGDMGPPG--IPGLLGLQGPPGPPGVPGPPGPGGSPGLP--GE 690 700 710 720 730 450 460 470 480 490 500 pF1KB4 ICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLG : :: ::::: : : .: .: : : .: ::. : :::: :: : CCDS63 IGFPGKPGPPGPTGPPGKDGPNGPPGPPGT----------KGEPGERGEDGLPGKPGLRG 740 750 760 770 780 510 520 530 540 550 560 pF1KB4 FPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAP :..: :. : : :::: :: ::. : :..:: :. : .::.:::.:: : : CCDS63 EIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGE-LGLPGLKGDRGEKGEAGPA 790 800 810 820 830 840 570 580 590 600 610 620 pF1KB4 GLPGLPGTPG----QDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGF : :::::: . . .:: ::::: ::. : ::.::: : ::..::.:: CCDS63 GPPGLPGTTSLFTPHPRMPGEQGPKGE------KGDPGLPGEPGLQGRPGELGPQGPT-- 850 860 870 880 890 630 640 650 660 670 pF1KB4 GPPGPVGEKGIQGV---AGNPGQPG---IPGPKGDPGQTITQPGKPGLPGNPGRDGDVGL :::: :..: .:. ::::: :: :::.: :: .. :: : ::. :. :. : CCDS63 GPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPG-SVGAPGLRGTPGKDGERGEKGA 900 910 920 930 940 950 680 690 700 710 720 730 pF1KB4 PGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRI------ :. : :: : : ::. : :: :: : : :: .: ::.::: :. .. :.. CCDS63 AGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKAACGKVRGSENC 960 970 980 990 1000 1010 740 750 760 770 780 pF1KB4 --------GLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGP : .: :: :: :: .:.::... ::::: : :: ::. : .: ::::: :: CCDS63 ALGGQCVKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGP 1020 1030 1040 1050 1060 1070 790 800 810 820 830 pF1KB4 PGRTGLDGLPGPKGDVGPNGQPG--PMGPPGLPGIGVQG-----PPGPPGIPGPIGQPGL :: :: :: :. :: :.:: . :: .. .. ::::::. ::: CCDS63 AGR---DGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGL------PGL 1080 1090 1100 1110 1120 840 850 860 870 880 890 pF1KB4 HGIPGEKGDPGPPGLD-VPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGE :. :.:: :: :: . . : :: : ::.:: :: :: :: : : : : : .:. CCDS63 PGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGH 1130 1140 1150 1160 1170 1180 900 910 920 930 940 950 pF1KB4 MGM---MGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGP :. ::::: ::: :: .:. : : :.::.:: :: : .: .: ::.:: : CCDS63 PGVPGFMGPPGNPGP---PGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGK 1190 1200 1210 1220 1230 1240 960 970 980 990 1000 1010 pF1KB4 MDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLP . :. : :::: : ::. ::.: .: : :: : .:. : ::: : .: ::: CCDS63 EGRD--GKPGPPGEPGKAGEPGLPGPEGARG-P--PGFKGHTGDSGAPGPRGESGAMGLP 1250 1260 1270 1280 1290 1020 1030 1040 1050 1060 1070 pF1KB4 GQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPG---LPGQKGDKGDPGIS :: :: :: : : : :::: .:::: .: ::.:: :: :::::.::. : CCDS63 GQEGL---PGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENG-- 1300 1310 1320 1330 1340 1350 1080 1090 1100 1110 1120 1130 pF1KB4 SIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPG : ::::. ::.: :: :: : :: .: .:: :: :: ::. : ::. : :::: CCDS63 SPGLPGFLGPRGPPGEPGEKGVPGKEG------VPGKPGEPGFKGERGDPGIKGDKGPPG 1360 1370 1380 1390 1400 1140 1150 1160 1170 1180 1190 pF1KB4 PKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGN :: : :: :: :. : .: : ::. :: : : ::: :.:: :.. :.. . CCDS63 GKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGES--PSMETLRR 1410 1420 1430 1440 1450 1460 1200 1210 1220 1230 1240 1250 pF1KB4 PGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPK : :.. . : . .. .: :.. . . :: ::::: :: .: CCDS63 LIQEEL----GKQLETRLAYLLAQ--MP-----PAY--MKSSQGRPGPPGPPGK--DGLP 1470 1480 1490 1500 1510 1260 1270 1280 1290 1300 1310 pF1KB4 GNPGPQGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNP : ::.: ::::: : ::: : : : :::.: :.:: ::. ::.:..::::. :.: CCDS63 GRAGPMGEPGRPGQGGLEGPSG-PI--GPKGERGAKGDPGAPGV-GLRGEMGPPGIPGQP 1520 1530 1540 1550 1560 1320 1330 1340 1350 1360 1370 pF1KB4 GRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIII :.:: . ::::.:: :.: .:: :.::: ::::::: :: . . CCDS63 GEPGY----AKDGLPGIPG------PQG---ETGPAGHPGLPGPPGPPGQCDPSQCAYFA 1570 1580 1590 1600 1610 1380 1390 1400 1410 1420 1430 pF1KB4 KGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQ . : : .. : CCDS63 SLAARPGNVKGP 1620 >>CCDS11561.1 COL1A1 gene_id:1277|Hs108|chr17 (1464 aa) initn: 720 init1: 720 opt: 3037 Z-score: 1116.1 bits: 219.3 E(32554): 7.6e-56 Smith-Waterman score: 3450; 46.2% identity (56.1% similar) in 1213 aa overlap (180-1385:109-1212) 150 160 170 180 190 200 pF1KB4 GIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPP :..: : :: :: :: :::: : :: : CCDS11 KNCPGAEVPEGECCPVCPDGSESPTDQETTGVEGPKGDTGPRGPRGPAGPPGRDGIPGQP 80 90 100 110 120 130 210 220 230 240 250 260 pF1KB4 GLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPP ::::: : : : :::: :... : : . : ..:: :: CCDS11 GLPGPPG--------PPGPP------GPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPS 140 150 160 170 180 270 280 290 300 310 320 pF1KB4 GPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGE :: :. :::: :: .: .: ::::. : : : : :: :: :: : :.::: :: CCDS11 GPRGLPGPPGAPG-PQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGE 190 200 210 220 230 240 330 340 350 360 370 380 pF1KB4 KGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPG .: :::: : . :::. : ::. :. :: : ::. : : .: :: :: : CCDS11 RG------PPGPQG-ARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENG 250 260 270 280 290 390 400 410 420 430 440 pF1KB4 AAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDE : : :: :.:::::. :: ::: : :. :: : :::::.:: CCDS11 AP--GQMGPRGLPGERGR------PGA--PGPAGARGNDGATGAAGPPGPTGP------- 300 310 320 330 450 460 470 480 490 500 pF1KB4 ICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLG :::: ::. : :: : :: .:..: :. : :: :: : :: :. : CCDS11 ---AGPPGFPGAVGAKGEAGPQGPRGSEGPQ-------GVRGEPGPPGPAGAAGPAGNPG 340 350 360 370 380 510 520 530 540 550 560 pF1KB4 FPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAP :: : :: :: : : ::.::: : :. : . : : :: ::..:: :.::. CCDS11 ADGQPGAKGANGAPGIAGAPGFPGARG-PSGPQGPGGP------PGPKGNSGEPGAPGSK 390 400 410 420 430 440 570 580 590 600 610 620 pF1KB4 GLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPG : : : :: :. : ::: :: : .: :: :: :::: ::. : :: . : :: CCDS11 GDTGAKGEPGPVGVQGPPGPAGEEGK---RGARGEPGPTGLPGPPGERG--GPGSRGFPG 450 460 470 480 490 630 640 650 660 670 680 pF1KB4 PVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQP : : .: ::. :.:: ::::.::.. :.:: : :: : .: ::.:: :. CCDS11 ADGVAGPKGPAGERGSPGPAGPKGSPGEA----GRPGEAGLPGAKGLTGSPGSPGPDGKT 500 510 520 530 540 550 690 700 710 720 730 740 pF1KB4 GLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKG : :: :. :.:: :: :: : : :.::: :: : ::. : .: ::::: :: : CCDS11 GPPGPAGQDGRPGPPGP--PGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAG 560 570 580 590 600 610 750 760 770 780 790 800 pF1KB4 EPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGP . : : : :::: :. :: :.:: :: : :: ..::::: .:: :: CCDS11 KDGEA--GAQGPPG-PA-----GPAGERGEQGPAGSPG---FQGLPGP---AGP---PGE 620 630 640 650 810 820 830 840 850 860 pF1KB4 MGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPG : :: :: :: : ::: : : .:.:::.: :::: :: : :.:: : CCDS11 AGKPG-----EQGVPGDLGAPGPSGARGERGFPGERGVQGPPG--PAGPRGANGAPGNDG 660 670 680 690 700 870 880 890 900 910 920 pF1KB4 APGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQG : : : ::.:: : : .:.:: .: :. :: : : : : .: :: : :: : CCDS11 AKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTG 710 720 730 740 750 760 930 940 950 960 970 980 pF1KB4 QPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGD : :::.: :.::: : :: :: :. :..:::: :: : .:: : .: :: CCDS11 PIGPPGPAGAPGDKGESGPSGPAGPTGAR--GAPGDRGEPGPPGPAGFAGPPGADGQPGA 770 780 790 800 810 820 990 1000 1010 1020 1030 1040 pF1KB4 PGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMG------FPGPQGVEGP :.:: .: : ::::: : : :: : .: :: ::. :. : ::: : :: CCDS11 KGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGP 830 840 850 860 870 880 1050 1060 1070 1080 1090 1100 pF1KB4 PGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDP ::::: : :: :: :..: :: : . :: :.:: : :: :: : :.: CCDS11 PGPSGNAGPPGPPGPAGKEGGKGPRGET--------GPAGRPGEVGPPGPPGPAGEKGSP 890 900 910 920 930 1110 1120 1130 1140 1150 1160 pF1KB4 GLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPP : : :.::. : :. : :. : :: .: : :: :: :::: : .: :. ::: CCDS11 GADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPP 940 950 960 970 980 990 1170 1180 1190 1200 1210 1220 pF1KB4 GEKGKPGQDGIPGPAGQKGEPGQPGF-GNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPK : : :: : :: .:..: :: : : : :: : :. : .: :: :: :: ::: CCDS11 GPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPV 1000 1010 1020 1030 1040 1050 1230 1240 1250 1260 1270 1280 pF1KB4 GEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGLPGPEGPPGLPGNGGIKG : : : : :: :: : ::. : .: ::::: : : : .: :. :. :..: CCDS11 GPAGKSGDRGETGPAGPAGPVGPV--GARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSG 1060 1070 1080 1090 1100 1110 1290 1300 1310 1320 1330 1340 pF1KB4 EKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPG .: :: :: :: : .: .:: : .: :: : : : :::: : :: : : : CCDS11 LQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPG---PRGRTG 1120 1130 1140 1150 1160 1170 1350 1360 1370 1380 1390 1400 pF1KB4 SAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPT .::: : :: :::::: ::: . .. .. :: .. : CCDS11 DAGPVGPPG---PPGPPGPPGPPSAGFDFSFLPQPPQEKAHDGGRYYRADDANVVRDRDL 1180 1190 1200 1210 1220 1410 1420 1430 1440 1450 1460 pF1KB4 GPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPGTSSVAHGF CCDS11 EVDTTLKSLSQQIENIRSPEGSRKNPARTCRDLKMCHSDWKSGEYWIDPNQGCNLDAIKV 1230 1240 1250 1260 1270 1280 >>CCDS76010.1 COL4A6 gene_id:1288|Hs108|chrX (1707 aa) initn: 3760 init1: 1030 opt: 3032 Z-score: 1113.6 bits: 219.1 E(32554): 1e-55 Smith-Waterman score: 4412; 48.4% identity (61.3% similar) in 1451 aa overlap (17-1406:18-1429) 10 20 30 40 50 pF1KB4 MKLRGVSLAAGLFLLALSLWGQPAEAAACYGCSPGSKCDCSGIKGEKGERGFPGLEGHP :. :. . . : : . ...:.: :: .:. : :..: CCDS76 MHPGLWLLLVTLCLTEELAAAGEKSYGKPCGGQDCSGSCQCFPEKGARGRPGPIGIQGPT 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB4 GLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQ : :: : : : .:..: :. :: :::: .:: :.::: : :.:: ::. : :: CCDS76 GPQGFTGSTGLSGLKGERGFPGLLGPYGPKGDKGPMGVPGFLGINGIPGHPGQPGPRGPP 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB4 GIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPP :. :::::.: :::: :.::: :::: :: : ::.: . .:. : ::.:: :: CCDS76 GLDGCNGTQGAVGFPGPDGYPGLLGPPGLPGQKGSKGDP-VLAPGSFKGMKGDPGLPGLD 130 140 150 160 170 180 190 200 210 220 230 pF1KB4 GIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPG :: : : :.:: .:: :::::.::::::: :: :::::.::: :: ::. :: :: : CCDS76 GITGPQGAPGFPGAVGPAGPPGLQGPPGPPGPLGPDGNMGLGFQGEKGVKGDVGLPGPAG 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB4 PPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPG----GEKGEKGEQG--- :: . .: . . : :: .: :. :: : ::: :::: :: ::::::::.: CCDS76 PPPSTGELEF---MGFPKGKKGSKGEPGPKGFPGISGPPGFPGLGTTGEKGEKGEKGIPG 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB4 EPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTG :: :: :..: .: :: : : :.:: : .: .::::: : ::: . : :. CCDS76 LPGPRGPMGSEGVQGPPGQQGKKGTLGFPGLNGFQGIEGQKGDIGLPGPD-VFIDIDGAV 300 310 320 330 340 350 360 370 380 390 400 410 pF1KB4 ITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPG-AAVMGPPGPPGFPGERGQKGDE :. :. :. :.::::: ::..:. :..:: :.:: :. ..: : :: :::: :::. CCDS76 IS-GNPGDPGVPGLPGLKGDEGIQGLRGPSGVPGLPALSGVPGALGPQGFPG---LKGDQ 360 370 380 390 400 410 420 430 440 450 460 470 pF1KB4 GPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSD-EICEPGPPGPPGSPGDKGLQGE : :: . : :: :: :::::::: :: : . : . : :: :..: .:. CCDS76 GNPGRTTIGAAGL---PGRDGLPGPPGPPGPPSPEFETETLHNKESGFPGLRGEQGPKGN 420 430 440 450 460 480 490 500 510 520 pF1KB4 QGVKGDKGDTCFNCIGTGI--SGPPGQPGLPGLPGPPGSLGFPGQKG---EKGQAGATGP :.:: :::. : :. .::::.:: : ::: : .:.:: :: ..:..:: :: CCDS76 LGLKGIKGDSGFCACDGGVPNTGPPGEPG-P--PGPWGLIGLPGLKGARGDRGSGGAQGP 470 480 490 500 510 520 530 540 550 560 570 580 pF1KB4 KGLPGIPGAPGAPGFPGSKGEPGDIL-TFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLP : ::. : : : :.:::: :: :. :: ::.:. :: :. :. : ::.::.: CCDS76 AGAPGLVGPLGPSGPKGKKGEP--ILSTIQGMPGDRGDSGSQ---GFRGVIGEPGKDGVP 530 540 550 560 570 580 590 600 610 620 630 pF1KB4 GLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGF------GPPGPVGEKGIQG :::: : :: : .: ::. :::::::. : ::::. : ::: : : .: CCDS76 GLPGLPGLPGD----GGQGFPGEKGLPGLPGEKGHPGPPGLPGNGLPGLPGPRGLPGDKG 590 600 610 620 630 640 650 660 670 680 pF1KB4 VAGNPGQPGIPGPKGD-------PGQTITQ---------PGKPGLPGNPGRDGDVGLPGD : ::: :.:: ::: :. :. ::. : : :: : : :. CCDS76 KDGLPGQQGLPGSKGDCCCREVGKGDLDTERGITLPCIIPGSYGPSGFPGTPGFPGPKGS 640 650 660 670 680 690 690 700 710 720 730 pF1KB4 PGLPGQPGLPGIPGSKGEPGIPGI----GLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGP :::: :: :: ::::::: ::. ::: :::.: :.:: :: :: : :. : CCDS76 RGLPGTPGQPGSSGSKGEPGSPGLVHLPELPGFPGPRGEKGLPGFPGLPGKDGLPGMIGS 700 710 720 730 740 750 740 750 760 770 780 790 pF1KB4 PGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPK :: :: : :. : : :: :: :. : : :: :.:: : :. :: ::: CCDS76 PGLPGSKGATGDIFGAENGAPGEQGLQGLTGHKGFLGDSGLPGLKGVHGKPGL---LGPK 760 770 780 790 800 810 800 810 820 830 840 850 pF1KB4 GDVGPNGQPGPMGPPGLPGI-GVQGPPGPPGIPGPIGQPGLHGIPGEKGD---PGPPGLD :. : : :: .: :: :: : : : :.:: : ::. : ::.:: :::: CCDS76 GERGSPGTPGQVGQPGTPGSSGPYGIKGKSGLPGAPGFPGISGHPGKKGTRGKKGPPGSI 820 830 840 850 860 870 860 870 880 890 900 910 pF1KB4 VP-GPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIP : : :: .: :: :: : : :::::. : . :: : :: .:..: :: :: ::: CCDS76 VKKGLPGLKGLPGNPGLVGLKGSPGSPGVAGLPALSGPKGEKGSVGFVGFPGIPGLPGIP 880 890 900 910 920 930 920 930 940 950 960 970 pF1KB4 GRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDP-NLLGSKGEKGEPGLP : :. :. :. : .: : : ::::..:.:: : :.: : . : ::.:: : CCDS76 GTRGLKGIPGSTGKMGPSGRAGTPGEKGDRGNPGPVGIPSPRRPMSNLWLKGDKGSQGSA 940 950 960 970 980 990 980 990 1000 1010 1020 1030 pF1KB4 GIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGP-PGPKGNPGLPGQPGLIGPPGLKGTIGD : : ::.: .: : :: ::: : ::::: : .:.:: :: :. : :::::. : CCDS76 GSNGFPGPRGDKGEAGRPGPPGLPGAPGLPGIIKGVSGKPGPPGFMGIRGLPGLKGSSGI 1000 1010 1020 1030 1040 1050 1040 1050 1060 1070 1080 1090 pF1KB4 MGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYP :::: : : : : :: ::. :::: :::.:. .. . : :::::.:: :. CCDS76 TGFPGMPGESGSQGIRGSPGLPGASGLPGLKGDNGQ----TVEISGSPGPKGQPGESGFK 1060 1070 1080 1090 1100 1100 1110 1120 1130 1140 1150 pF1KB4 GNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPV :. : : .:. :.:: : : : : :.::.:: :: :. : :: :: :. : . CCDS76 GTKGRDGLIGNIGFPGNKGEDGKVGVSGDVGLPGAPGFPGVAGMRGEPGLPGSSGHQGAI 1110 1120 1130 1140 1150 1160 1160 1170 1180 1190 1200 pF1KB4 GGGGHPGQPGPPGEKGKPGQ---DGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGG : : :: :: : : :: .:.:: : .: :: : ::: :::: .:.:: : CCDS76 GPLGSPGLIGPKGFPGFPGLHGLNGLPGTKGTHGTPGPSITGVPGPAGLPGPKGEKGYPG 1170 1180 1190 1200 1210 1220 1210 1220 1230 1240 1250 1260 pF1KB4 LPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGL--- . :: : :: :: .:. : .::::.::: : ::.:: .: :. : : :::::: CCDS76 I-GI-GAPGKPGLRGQKGDRGFPGLQGPAGLPGAPGISL--PSLIAGQPGDPGRPGLDGE 1230 1240 1250 1260 1270 1280 1270 1280 1290 1300 1310 1320 pF1KB4 ---PGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGD ::: :::: :: .. .:. :.:: ::.:: : ::::: ::..: ::. ::.::.:. CCDS76 RGRPGPAGPPGPPGPSSNQGDTGDPGFPGIPGPKGPKGDQGIPGFSGLPGELGLKGMRGE 1290 1300 1310 1320 1330 1340 1330 1340 1350 1360 1370 pF1KB4 PGLPGVPGFPGMKGPSGVPG---SAGPEGEPGLIGPPGPPGLPGPSGQSIIIK-GDAGPP ::. :.:: : : : :: .:::.: :: : :: :..... . : : : CCDS76 PGFMGTPGKVGPPGDPGFPGMKGKAGPRGSSGLQGDPGQT----PTAEAVQVPPGPLGLP 1350 1360 1370 1380 1390 1400 1380 1390 1400 1410 1420 1430 pF1KB4 GIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLD :: : ::: : :: ::: :: : : :: CCDS76 GIDGIPGLTGDPGAQGPVGLQGSKGLPGIPGKDGPSGLPGPPGALGDPGLPGLQGPPGFE 1410 1420 1430 1440 1450 1460 >-- initn: 850 init1: 456 opt: 1216 Z-score: 461.0 bits: 98.3 E(32554): 2.3e-19 Smith-Waterman score: 1216; 60.8% identity (82.0% similar) in 278 aa overlap (1408-1683:1431-1705) 1380 1390 1400 1410 1420 1430 pF1KB4 PGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGL ::..: :. : : ::::::: : :. CCDS76 PGIDGIPGLTGDPGAQGPVGLQGSKGLPGIPGKDGPSGLPGPPGALGDPGLPGLQGPPGF 1410 1420 1430 1440 1450 1460 1440 1450 1460 1470 1480 1490 pF1KB4 DGPPGPDGLQGPPGPPGTSSVAHGFLITRHSQTTDAPQCPQGTLQVYEGFSLLYVQGNKR .: :: .: : :: :: .:. :. ...:::. ..: :: : :.. :.:::.:.:... CCDS76 EGAPGQQGPFGMPGMPG-QSMRVGYTLVKHSQSEQVPPCPIGMSQLWVGYSLLFVEGQEK 1470 1480 1490 1500 1510 1500 1510 1520 1530 1540 1550 pF1KB4 AHGQDLGTAGSCLRRFSTMPFMFCNINNVCNFASRNDYSYWLSTPEPMPMSMQPLKGQSI ::.:::: ::::: :::::::..::::.::..: ::: :::::: :.:: .:.. .: CCDS76 AHNQDLGFAGSCLPRFSTMPFIYCNINEVCHYARRNDKSYWLSTTAPIPM--MPVSQTQI 1520 1530 1540 1550 1560 1570 1560 1570 1580 1590 1600 1610 pF1KB4 QPFISRCAVCEAPAVVIAVHSQTIQIPHCPQGWDSLWIGYSFMMHTSAGAEGSGQALASP .::::.:::::. .:::::: : ::.:: :: ::::::::.:::.:::::.::.:.:: CCDS76 PQYISRCSVCEAPSQAIAVHSQDITIPQCPLGWRSLWIGYSFLMHTAAGAEGGGQSLVSP 1580 1590 1600 1610 1620 1630 1620 1630 1640 1650 1660 1670 pF1KB4 GSCLEEFRSAPFIECHG-RGTCNYYANSYSFWLATVDVSDMFSK-PQSETLKAGDLRTRI :::::.::..::::: : ::::.:.::.:::::.::. ..:.. : :::::::.:.::. CCDS76 GSCLEDFRATPFIECSGARGTCHYFANKYSFWLTTVEERQQFGELPVSETLKAGQLHTRV 1640 1650 1660 1670 1680 1690 1680 pF1KB4 SRCQVCMKRT :::::::: CCDS76 SRCQVCMKSL 1700 >>CCDS41297.1 COL16A1 gene_id:1307|Hs108|chr1 (1604 aa) initn: 1954 init1: 816 opt: 3017 Z-score: 1108.5 bits: 218.1 E(32554): 2e-55 Smith-Waterman score: 3424; 44.6% identity (56.4% similar) in 1297 aa overlap (276-1451:343-1576) 250 260 270 280 290 300 pF1KB4 EQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKP----- : :::::. ::::: .:. : .: CCDS41 ADECPPCVHGARDSNVTLAPSGPKGGKGERGLPGPPGS-KGEKGARGNDCVRISPDAPLQ 320 330 340 350 360 370 310 320 330 340 350 pF1KB4 ---GKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGE : ::.:. : : : :: :: :. ::::. : : :: :: ::: .:: CCDS41 CAEGPKGEKGESGALGPSGLPGSTGEKGQKGEKGDGGIKGVPGKPGRD-GRPGEICVIGP 380 390 400 410 420 430 360 370 380 390 400 410 pF1KB4 KGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFP-GERGQKGDEGPPGI ::. : ::. : .: : :: ::::::::: .. : :: :: : : .:.::. : :: CCDS41 KGQKGDPGFVGPEGLAGEPG---PPGLPGPPGIGLPGTPGDPGGPPGPKGDKGSSGIPGK 440 450 460 470 480 420 430 440 450 460 470 pF1KB4 SIPGPPGLDGQPGAPGLPGPPGPAGPHIPPS--DEICEPGPPGPPGSPGD----KGLQGE :: : :.::. : : : . : .: . . . :: ::: : ::: .: : CCDS41 E--GPGGKPGKPGVKGEKGDPCEVCPTLPEGFQNFVGLPGKPGPKGEPGDPVPARGDPGI 490 500 510 520 530 540 480 490 500 510 520 pF1KB4 QGVKGDKGDTCFNC---IG-------TGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQA ::.::.::. :..: .: :: :: :.::. :::: :: : :: :::::. CCDS41 QGIKGEKGEPCLSCSSVVGAQHLVSSTGASGDVGSPGF-GLPGLPGRAGVPGLKGEKGNF 550 560 570 580 590 600 530 540 550 560 570 pF1KB4 GATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMK----GDKGELGSPGAPGLPGLPG : .:: : :: :: : :. :.:::: . :... :: .. :: : : :: CCDS41 GEAGPAGSPGPPGPVGPAGIKGAKGEPCE--PCPALSNLQDGDVRVVALPGPSGEKGEPG 610 620 630 640 650 660 580 590 600 610 620 630 pF1KB4 TPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGF-GPPGPVGEKG :: :::: : :: : ::. : ::.:: :: : : : :: :: :: :::: CCDS41 PPGF-GLPGKQGKAGERGLKGQKGDAGNPGDPGTPGTTGRPGLSGEPGVQGPAGPKGEKG 670 680 690 700 710 720 640 650 660 670 680 pF1KB4 --------IQG-VAGNPGQPGIPGPKGDPG-QTITQPGKPGLPGNPGRDGDVGLPGDPGL .:: :. :.:: :::::. : . . .::::: :: :: .: :: : : CCDS41 DGCTACPSLQGTVTDMAGRPGQPGPKGEQGPEGVGRPGKPGQPGLPGVQGPPGLKGVQGE 730 740 750 760 770 780 690 700 710 720 730 740 pF1KB4 PGQPGLPGIPGSKGEPGIPGI-GLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGF :: :: :. : .:::: ::. :. : :::.: :: : :: :.:: : :: :::: CCDS41 PGPPGR-GVQGPQGEPGAPGLPGIQGLPGPRGPPGPTGEKGAQGSPGVKGATGPVGPPG- 790 800 810 820 830 750 760 770 780 790 800 pF1KB4 PGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGL--DGLPGPKGD-V . .: :: : : :: : : ::.:..: :: . :.. : .:.:: : . CCDS41 ASVSGPPG--RDGQQGQTGLRGTPGEKGPRGEKGEPGECSCPSQGDLIFSGMPGAPGLWM 840 850 860 870 880 890 810 820 830 840 850 pF1KB4 GPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGL--DVPGPP : . ::::.::::.: :::::::. :::.:.::..: :: ::: .. . : CCDS41 GSSWQPGPQGPPGIP-----GPPGPPGV------PGLQGVPGNNGLPGQPGLTAELGSLP 900 910 920 930 940 860 870 880 pF1KB4 ---------------GERGSPGI---PGAPGPIGPPGSPGL------------PGKAGAS :.:. :: : : : :: ::: : : CCDS41 IEQHLLKSICGDCVQGQRAHPGYLVEKGEKGDQGIPGVPGLDNCAQCFLSLERPRAEEAR 950 960 970 980 990 1000 890 900 910 920 930 940 pF1KB4 GFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLP : ...:. : .: :: ::: :.::. : : : : : :: :: : :. : :::: CCDS41 G-DNSEGDPGCVGSPGLPGPPGLPGQRGEEGPPGMRGSPGPPGPIGPPGFPGAVGSPGLP 1010 1020 1030 1040 1050 1060 950 960 970 980 990 1000 pF1KB4 GPPGPMD-PNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPK : : .: :.::: : :: :: ::..:: : :. :. : : .:. : ::::: . CCDS41 GLQGERGLTGLTGDKGEPGPPGQPGYPGATGPPGLPGIKGERGYTGSAGEKGEPGPPGSE 1070 1080 1090 1100 1110 1120 1010 1020 1030 1040 1050 1060 pF1KB4 GNPGLPGQ--P-GLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDK : :: :: : : :: : .: ::.:: : : ::::: : ::. :::: :: ...: CCDS41 GLPGPPGPAGPRGERGPQGNSGEKGDQGFQGQPGFPGPPGPPGFPGKVGSPGPPGPQAEK 1130 1140 1150 1160 1170 1180 1070 1080 1090 1100 1110 1120 pF1KB4 GDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPG :. :: ::.: :: :: :: :::.: .: :: : : :: .:.:: : :: CCDS41 GSEGIR--------GPSGLPGSPGPPGPPGIQGPAGLDGLDGKDGKPGLRGDPGPAGPPG 1190 1200 1210 1220 1230 1130 1140 1150 1160 1170 1180 pF1KB4 TPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPG :::: :: .: .::::: : :.::::: :.:: .: :: : .:.:: CCDS41 LMGPPGFKGKTG---HPGLPGPKGDC------GKPGPPGSTGRPGAEGEPGAMGPQGRPG 1240 1250 1260 1270 1280 1190 1200 1210 1220 1230 1240 pF1KB4 QPGF-GNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPG :: : ::::: :: .:. .. :: : .: : .:. :. : ::::: :: CCDS41 PPGHVGPPGPPGQPG------PAGISAV----GLKGDRGATGERGLAGLPGQPGPPGHPG 1290 1300 1310 1320 1330 1250 1260 1270 1280 1290 1300 pF1KB4 PALE-GPKGNPGPQGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQG : : : : : .::::. :. :: :: : :: .: ::. :. :. :.:: :: .:..: CCDS41 PPGEPGTDGAAGKEGPPGKQGFYGPPGPKGDPGAAGQKGQAGEKGRAGMPGGPGKSGSMG 1340 1350 1360 1370 1380 1390 1310 1320 1330 pF1KB4 P---PGLQGNPGRPGLNGMKGDPGLPGVPG------------------------------ : :: :. :.:: : .:.:::::::: CCDS41 PVGPPGPAGERGHPGAPGPSGSPGLPGVPGSMGDMVNYDEIKRFIRQEIIKMFDERMAYY 1400 1410 1420 1430 1440 1450 1340 1350 1360 1370 1380 pF1KB4 -----FPG-MKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQP :: : . : :: : .: :: : :: ::::: :. .: : ::. : : CCDS41 TSRMQFPMEMAAAPGRPGPPGKDGAPGRPGAPGSPGLPGQIGR----EGRQGLPGVRGLP 1460 1470 1480 1490 1500 1510 1390 1400 1410 1420 1430 1440 pF1KB4 GLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPD : :: : : :. : .: :: :: .: ::. :. : : :: : :. ::::: CCDS41 GTKGEKGDIGI-GIAGENGLPGPPGPQGPPGY----GKMGATGPMGQQGIPGIPGPPGPM 1520 1530 1540 1550 1560 1450 1460 1470 1480 1490 1500 pF1KB4 GLQGPPGPPGTSSVAHGFLITRHSQTTDAPQCPQGTLQVYEGFSLLYVQGNKRAHGQDLG : : : CCDS41 GQPGKAGHCNPSDCFGAMPMEQQYPPMKTMKGPFG 1570 1580 1590 1600 >>CCDS76008.1 COL4A6 gene_id:1288|Hs108|chrX (1633 aa) initn: 3059 init1: 1119 opt: 2896 Z-score: 1065.0 bits: 210.0 E(32554): 5.4e-53 Smith-Waterman score: 4106; 49.3% identity (61.4% similar) in 1334 aa overlap (17-1309:18-1306) 10 20 30 40 50 pF1KB4 MKLRGVSLAAGLFLLALSLWGQPAEAAACYG--CSPGSKCDCSGIKGEKGERGFPGLEG :. :. . . : : :: :: :.: :: .:. : :..: CCDS76 MHPGLWLLLVTLCLTEELAAAGEKSYGKPCGGQDCS-GS-CQCFPEKGARGRPGPIGIQG 10 20 30 40 50 60 70 80 90 100 110 pF1KB4 HPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPG : :: : : : .:..: :. :: :::: .:: :.::: : :.:: ::. : : CCDS76 PTGPQGFTGSTGLSGLKGERGFPGLLGPYGPKGDKGPMGVPGFLGINGIPGHPGQPGPRG 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB4 PQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPG : :. :::::.: :::: :.::: :::: :: : ::.: . .:. : ::.:: :: CCDS76 PPGLDGCNGTQGAVGFPGPDGYPGLLGPPGLPGQKGSKGDP-VLAPGSFKGMKGDPGLPG 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB4 PPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGP :: : : :.:: .:: :::::.::::::: :: :::::.::: :: ::. :: :: CCDS76 LDGITGPQGAPGFPGAVGPAGPPGLQGPPGPPGPLGPDGNMGLGFQGEKGVKGDVGLPGP 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB4 PGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPG----GEKGEKGEQG- ::: . .: . . : :: .: :. :: : ::: :::: :: ::::::::.: CCDS76 AGPPPSTGELEF---MGFPKGKKGSKGEPGPKGFPGISGPPGFPGLGTTGEKGEKGEKGI 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB4 --EPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPG :: :: :..: .: :: : : :.:: : .: .::::: : ::: . : : CCDS76 PGLPGPRGPMGSEGVQGPPGQQGKKGTLGFPGLNGFQGIEGQKGDIGLPGPD-VFIDIDG 300 310 320 330 340 350 360 370 380 390 400 pF1KB4 TGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPG-AAVMGPPGPPGFPGERGQKG . :. :. :. :.::::: ::..:. :..:: :.:: :. ..: : :: :::: :: CCDS76 AVIS-GNPGDPGVPGLPGLKGDEGIQGLRGPSGVPGLPALSGVPGALGPQGFPG---LKG 360 370 380 390 400 410 420 430 440 450 460 pF1KB4 DEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSD-EICEPGPPGPPGSPGDKGLQ :.: :: . : :: :: :::::::: :: : . : . : :: :..: . CCDS76 DQGNPGRTTIGAAGL---PGRDGLPGPPGPPGPPSPEFETETLHNKESGFPGLRGEQGPK 410 420 430 440 450 460 470 480 490 500 510 520 pF1KB4 GEQGVKGDKGDTCFNCIGTGI--SGPPGQPGLPGLPGPPGSLGFPGQKG---EKGQAGAT :. :.:: :::. : :. .::::.:: : ::: : .:.:: :: ..:..:: CCDS76 GNLGLKGIKGDSGFCACDGGVPNTGPPGEPG-P--PGPWGLIGLPGLKGARGDRGSGGAQ 470 480 490 500 510 520 530 540 550 560 570 580 pF1KB4 GPKGLPGIPGAPGAPGFPGSKGEPGDIL-TFPGMKGDKGELGSPGAPGLPGLPGTPGQDG :: : ::. : : : :.:::: :: :. :: ::.:. :: : . :. : ::.:: CCDS76 GPAGAPGLVGPLGPSGPKGKKGEP--ILSTIQGMPGDRGDSGSQG---FRGVIGEPGKDG 530 540 550 560 570 590 600 610 620 630 pF1KB4 LPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGF------GPPGPVGEKGI .::::: : :: : .: ::. :::::::. : ::::. : ::: : : CCDS76 VPGLPGLPGLPGD----GGQGFPGEKGLPGLPGEKGHPGPPGLPGNGLPGLPGPRGLPGD 580 590 600 610 620 630 640 650 660 670 680 690 pF1KB4 QGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPG .: : ::: :.:: :: : ::. : : :: : : :. :::: :: :: : CCDS76 KGKDGLPGQQGLPGSKGITLPCII-PGSYGPSGFPGTPGFPGPKGSRGLPGTPGQPGSSG 640 650 660 670 680 690 700 710 720 730 740 750 pF1KB4 SKGEPGIPGI----GLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPG :::::: ::. ::: :::.: :.:: :: :: : :. : :: :: : :. CCDS76 SKGEPGSPGLVHLPELPGFPGPRGEKGLPGFPGLPGKDGLPGMIGSPGLPGSKGATGDIF 700 710 720 730 740 750 760 770 780 790 800 810 pF1KB4 FALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGP : : :: :: :. : : :: :.:: : :. :: : :::. : : :: .: CCDS76 GAENGAPGEQGLQGLTGHKGFLGDSGLPGLKGVHGKPGLLG---PKGERGSPGTPGQVGQ 760 770 780 790 800 810 820 830 840 850 860 pF1KB4 PGLPGI-GVQGPPGPPGIPGPIGQPGLHGIPGEKGD---PGPPGLDVP-GPPGERGSPGI :: :: : : : :.:: : ::. : ::.:: :::: : : :: .: :: CCDS76 PGTPGSSGPYGIKGKSGLPGAPGFPGISGHPGKKGTRGKKGPPGSIVKKGLPGLKGLPGN 820 830 840 850 860 870 870 880 890 900 910 920 pF1KB4 PGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGL :: : : :::::. : . :: : :: .:..: :: :: :::: :. :. :. : CCDS76 PGLVGLKGSPGSPGVAGLPALSGPKGEKGSVGFVGFPGIPGLPGIPGTRGLKGIPGSTGK 880 890 900 910 920 930 930 940 950 960 970 980 pF1KB4 QGQPGLPGPTGEKGSKGEPGLPGPPGPMDP-NLLGSKGEKGEPGLPGIPGVSGPKGYQGL .: : : ::::..:.:: : :.: : . : ::.:: : : : ::.: .: CCDS76 MGPSGRAGTPGEKGDRGNPGPVGIPSPRRPMSNLWLKGDKGSQGSAGSNGFPGPRGDKGE 940 950 960 970 980 990 990 1000 1010 1020 1030 1040 pF1KB4 PGDPGQPGLSGQPGLPGP-PGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPG : :: ::: : ::::: : .:.:: :: :. : :::::. : :::: : : : CCDS76 AGRPGPPGLPGAPGLPGIIKGVSGKPGPPGFMGIRGLPGLKGSSGITGFPGMPGESGSQG 1000 1010 1020 1030 1040 1050 1050 1060 1070 1080 1090 1100 pF1KB4 PSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGL : :: ::. :::: :::.:. .. . : :::::.:: :. :. : : .:. :. CCDS76 IRGSPGLPGASGLPGLKGDNGQ----TVEISGSPGPKGQPGESGFKGTKGRDGLIGNIGF 1060 1070 1080 1090 1100 1110 1120 1130 1140 1150 1160 pF1KB4 PGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGE :: : : : : :.::.:: :: :. : :: :: :. : .: : :: :: : CCDS76 PGNKGEDGKVGVSGDVGLPGAPGFPGVAGMRGEPGLPGSSGHQGAIGPLGSPGLIGPKGP 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 1210 1220 pF1KB4 K--GKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKG . : :: :.::: ::: : ::.: : :: ::: ::::: :.::. : ::: : CCDS76 SITGVPGPAGLPGP---KGEKGYPGIGI-GAPGKPGLRGQKGDRGFPGLQGPAGLP---G 1170 1180 1190 1200 1210 1230 1240 1250 1260 1270 pF1KB4 EPGFHGFPG-VQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGLP----GPEGPPGLPGNG ::. ..:. . : :: :: :: :.: .: ::: :::: :: : : : ::.:: CCDS76 APGI-SLPSLIAGQPGDPGRPG--LDGERGRPGPAGPPGPPG-PSSNQGDTGDPGFPGIP 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 1330 pF1KB4 GIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPS : :: ::. : ::. :::: : .: :::: CCDS76 GPKGPKGDQGIPGFSGLPGELGLKGSSGLQGDPGQTPTAEAVQVPPGPLGLPGIDGIPGL 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 1390 pF1KB4 GVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGL CCDS76 TGDPGAQGPVGLQGSKGLPGIPGKDGPSGLPGPPGALGDPGLPGLQGPPGFEGAPGQQGP 1340 1350 1360 1370 1380 1390 >-- initn: 976 init1: 582 opt: 1364 Z-score: 514.4 bits: 108.2 E(32554): 2.5e-22 Smith-Waterman score: 1364; 59.0% identity (78.9% similar) in 327 aa overlap (1362-1683:1308-1631) 1340 1350 1360 1370 1380 pF1KB4 PGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPG--PSGQSIIIK-GDAGPPGIPGQPGLKG :: :..... . : : ::: : ::: : CCDS76 KGPKGDQGIPGFSGLPGELGLKGSSGLQGDPGQTPTAEAVQVPPGPLGLPGIDGIPGLTG 1280 1290 1300 1310 1320 1330 1390 1400 1410 1420 1430 1440 pF1KB4 LPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQG :: ::: :: : : :: ::..: :. : : ::::::: : :..: :: .: : CCDS76 DPGAQGPVGLQGSKGLPGIPGKDGPSGLPGPPGALGDPGLPGLQGPPGFEGAPGQQGPFG 1340 1350 1360 1370 1380 1390 1450 1460 1470 1480 1490 1500 pF1KB4 PPGPPGTSSVAHGFLITRHSQTTDAPQCPQGTLQVYEGFSLLYVQGNKRAHGQDLGTAGS :: :: .:. :. ...:::. ..: :: : :.. :.:::.:.:...::.:::: ::: CCDS76 MPGMPG-QSMRVGYTLVKHSQSEQVPPCPIGMSQLWVGYSLLFVEGQEKAHNQDLGFAGS 1400 1410 1420 1430 1440 1450 1510 1520 1530 1540 1550 1560 pF1KB4 CLRRFSTMPFMFCNINNVCNFASRNDYSYWLSTPEPMPMSMQPLKGQSIQPFISRCAVCE :: :::::::..::::.::..: ::: :::::: :.:: .:.. .: .::::.::: CCDS76 CLPRFSTMPFIYCNINEVCHYARRNDKSYWLSTTAPIPM--MPVSQTQIPQYISRCSVCE 1460 1470 1480 1490 1500 1510 1570 1580 1590 1600 1610 1620 pF1KB4 APAVVIAVHSQTIQIPHCPQGWDSLWIGYSFMMHTSAGAEGSGQALASPGSCLEEFRSAP ::. .:::::: : ::.:: :: ::::::::.:::.:::::.::.:.:::::::.::..: CCDS76 APSQAIAVHSQDITIPQCPLGWRSLWIGYSFLMHTAAGAEGGGQSLVSPGSCLEDFRATP 1520 1530 1540 1550 1560 1570 1630 1640 1650 1660 1670 1680 pF1KB4 FIECHG-RGTCNYYANSYSFWLATVDVSDMFSK-PQSETLKAGDLRTRISRCQVCMKRT :::: : ::::.:.::.:::::.::. ..:.. : :::::::.:.::.:::::::: CCDS76 FIECSGARGTCHYFANKYSFWLTTVEERQQFGELPVSETLKAGQLHTRVSRCQVCMKSL 1580 1590 1600 1610 1620 1630 1685 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Nov 2 22:54:55 2016 done: Wed Nov 2 22:54:56 2016 Total Scan time: 4.840 Total Display time: 0.970 Function used was FASTA [36.3.4 Apr, 2011]