FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB4486, 1685 aa 1>>>pF1KB4486 1685 - 1685 aa - 1685 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 14.5862+/-0.000627; mu= -13.2358+/- 0.040 mean_var=903.0862+/-189.744, 0's: 0 Z-trim(121.8): 812 B-trim: 1927 in 1/59 Lambda= 0.042679 statistics sampled from 37945 (38871) to 37945 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.672), E-opt: 0.2 (0.456), width: 16 Scan time: 16.530 The best scores are: opt bits E(85289) NP_000486 (OMIM: 301050,303630) collagen alpha-5(I (1685) 12890 811.2 0 NP_203699 (OMIM: 301050,303630) collagen alpha-5(I (1691) 12868 809.9 0 XP_016884749 (OMIM: 301050,303630) PREDICTED: coll (1690) 12720 800.7 0 XP_016884748 (OMIM: 301050,303630) PREDICTED: coll (1693) 12704 799.8 0 XP_011529151 (OMIM: 301050,303630) PREDICTED: coll (1696) 12698 799.4 0 XP_016884750 (OMIM: 301050,303630) PREDICTED: coll (1330) 9933 629.0 8.5e-179 XP_016884751 (OMIM: 301050,303630) PREDICTED: coll (1289) 9619 609.7 5.5e-173 XP_016884752 (OMIM: 301050,303630) PREDICTED: coll (1136) 8599 546.8 4.1e-154 NP_001836 (OMIM: 120130,175780,180000,607595,61177 (1669) 7031 450.5 6e-125 XP_011519350 (OMIM: 120130,175780,180000,607595,61 (1605) 6965 446.4 9.8e-124 NP_000082 (OMIM: 104200,120070,141200,203780) coll (1670) 5533 358.2 3.5e-97 XP_005246334 (OMIM: 104200,120070,141200,203780) P (1635) 5283 342.8 1.5e-92 XP_011508857 (OMIM: 104200,120070,141200,203780) P (1609) 5273 342.2 2.3e-92 XP_011508858 (OMIM: 104200,120070,141200,203780) P (1257) 4618 301.7 2.7e-80 XP_006712308 (OMIM: 104200,120070,141200,203780) P (1189) 4328 283.8 6.1e-75 XP_016858784 (OMIM: 104200,120070,141200,203780) P (1119) 4080 268.5 2.3e-70 XP_016861177 (OMIM: 120120,131705,131750,131850,13 (2924) 3940 260.4 1.7e-67 XP_005246337 (OMIM: 104200,120070,141200,203780) P (1051) 3818 252.4 1.6e-65 XP_016858788 (OMIM: 120131,203780) PREDICTED: coll (1518) 3427 228.5 3.6e-58 XP_011508863 (OMIM: 120131,203780) PREDICTED: coll (1608) 3427 228.5 3.7e-58 XP_016858787 (OMIM: 120131,203780) PREDICTED: coll (1608) 3427 228.5 3.7e-58 XP_011508864 (OMIM: 120131,203780) PREDICTED: coll (1608) 3427 228.5 3.7e-58 XP_011508862 (OMIM: 120131,203780) PREDICTED: coll (1612) 3427 228.5 3.7e-58 XP_011508861 (OMIM: 120131,203780) PREDICTED: coll (1612) 3427 228.5 3.7e-58 XP_016858785 (OMIM: 120131,203780) PREDICTED: coll (1659) 3427 228.5 3.8e-58 NP_000083 (OMIM: 120131,203780) collagen alpha-4(I (1690) 3427 228.6 3.8e-58 XP_005246338 (OMIM: 120131,203780) PREDICTED: coll (1690) 3427 228.6 3.8e-58 XP_005246339 (OMIM: 120131,203780) PREDICTED: coll (1505) 3368 224.9 4.4e-57 NP_690848 (OMIM: 610026) collagen alpha-1(XXII) ch (1626) 3185 213.6 1.1e-53 XP_016855828 (OMIM: 120326) PREDICTED: collagen al (1592) 3096 208.1 5e-52 XP_016855827 (OMIM: 120326) PREDICTED: collagen al (1593) 3051 205.4 3.4e-51 NP_000079 (OMIM: 114000,120150,130000,130060,16620 (1464) 3037 204.5 5.9e-51 XP_011529156 (OMIM: 300914,303631) PREDICTED: coll (1266) 3032 204.1 6.7e-51 XP_011529154 (OMIM: 300914,303631) PREDICTED: coll (1684) 3036 204.5 6.8e-51 NP_001274687 (OMIM: 300914,303631) collagen alpha- (1707) 3032 204.2 8.1e-51 XP_006724680 (OMIM: 300914,303631) PREDICTED: coll (1708) 3032 204.2 8.1e-51 XP_011539029 (OMIM: 120326) PREDICTED: collagen al (1302) 3017 203.2 1.3e-50 XP_011529155 (OMIM: 300914,303631) PREDICTED: coll (1680) 3018 203.4 1.5e-50 NP_001847 (OMIM: 120326) collagen alpha-1(XVI) cha (1604) 3017 203.3 1.5e-50 XP_011539028 (OMIM: 120326) PREDICTED: collagen al (1402) 2976 200.7 7.8e-50 XP_011539025 (OMIM: 120326) PREDICTED: collagen al (1573) 2976 200.7 8.4e-50 XP_011539026 (OMIM: 120326) PREDICTED: collagen al (1563) 2948 199.0 2.8e-49 NP_001274689 (OMIM: 300914,303631) collagen alpha- (1633) 2896 195.8 2.6e-48 NP_001274688 (OMIM: 300914,303631) collagen alpha- (1666) 2896 195.9 2.6e-48 NP_378667 (OMIM: 300914,303631) collagen alpha-6(I (1690) 2896 195.9 2.7e-48 NP_001838 (OMIM: 300914,303631) collagen alpha-6(I (1691) 2896 195.9 2.7e-48 XP_006717371 (OMIM: 608461,615155) PREDICTED: coll (1842) 2851 193.1 1.9e-47 XP_011517442 (OMIM: 608461,615155) PREDICTED: coll (1842) 2830 191.8 4.7e-47 XP_011517440 (OMIM: 608461,615155) PREDICTED: coll (1858) 2830 191.8 4.7e-47 NP_116277 (OMIM: 608461,615155) collagen alpha-1(X (1860) 2830 191.8 4.7e-47 >>NP_000486 (OMIM: 301050,303630) collagen alpha-5(IV) c (1685 aa) initn: 12890 init1: 12890 opt: 12890 Z-score: 4313.8 bits: 811.2 E(85289): 0 Smith-Waterman score: 12890; 100.0% identity (100.0% similar) in 1685 aa overlap (1-1685:1-1685) 10 20 30 40 50 60 pF1KB4 MKLRGVSLAAGLFLLALSLWGQPAEAAACYGCSPGSKCDCSGIKGEKGERGFPGLEGHPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 MKLRGVSLAAGLFLLALSLWGQPAEAAACYGCSPGSKCDCSGIKGEKGERGFPGLEGHPG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 LPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 LPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 IPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 IPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 IQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 IQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 PGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 PGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 GKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 GKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGN 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB4 IGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 IGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB4 PPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 PPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDT 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB4 CFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 CFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGF 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB4 PGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 PGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKG 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB4 ERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 ERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTIT 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB4 QPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 QPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGI 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB4 PGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 PGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFP 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB4 GPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 GPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHG 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB4 IPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 IPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGM 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB4 MGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 MGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLL 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB4 GSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 GSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLI 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB4 GPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 GPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPG 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB4 PKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 PKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPG 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KB4 NPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 NPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGL 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KB4 SGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 SGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPP 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KB4 GRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 GRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMK 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KB4 GDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 GDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGI 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KB4 PGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 PGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGP 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KB4 PGPDGLQGPPGPPGTSSVAHGFLITRHSQTTDAPQCPQGTLQVYEGFSLLYVQGNKRAHG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 PGPDGLQGPPGPPGTSSVAHGFLITRHSQTTDAPQCPQGTLQVYEGFSLLYVQGNKRAHG 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KB4 QDLGTAGSCLRRFSTMPFMFCNINNVCNFASRNDYSYWLSTPEPMPMSMQPLKGQSIQPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 QDLGTAGSCLRRFSTMPFMFCNINNVCNFASRNDYSYWLSTPEPMPMSMQPLKGQSIQPF 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KB4 ISRCAVCEAPAVVIAVHSQTIQIPHCPQGWDSLWIGYSFMMHTSAGAEGSGQALASPGSC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 ISRCAVCEAPAVVIAVHSQTIQIPHCPQGWDSLWIGYSFMMHTSAGAEGSGQALASPGSC 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KB4 LEEFRSAPFIECHGRGTCNYYANSYSFWLATVDVSDMFSKPQSETLKAGDLRTRISRCQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 LEEFRSAPFIECHGRGTCNYYANSYSFWLATVDVSDMFSKPQSETLKAGDLRTRISRCQV 1630 1640 1650 1660 1670 1680 pF1KB4 CMKRT ::::: NP_000 CMKRT >>NP_203699 (OMIM: 301050,303630) collagen alpha-5(IV) c (1691 aa) initn: 10244 init1: 10244 opt: 12868 Z-score: 4306.5 bits: 809.9 E(85289): 0 Smith-Waterman score: 12868; 99.6% identity (99.6% similar) in 1691 aa overlap (1-1685:1-1691) 10 20 30 40 50 60 pF1KB4 MKLRGVSLAAGLFLLALSLWGQPAEAAACYGCSPGSKCDCSGIKGEKGERGFPGLEGHPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_203 MKLRGVSLAAGLFLLALSLWGQPAEAAACYGCSPGSKCDCSGIKGEKGERGFPGLEGHPG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 LPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_203 LPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 IPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_203 IPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 IQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_203 IQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 PGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_203 PGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 GKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_203 GKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGN 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB4 IGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_203 IGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB4 PPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_203 PPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDT 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB4 CFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_203 CFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGF 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB4 PGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_203 PGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKG 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB4 ERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_203 ERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTIT 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB4 QPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_203 QPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGI 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB4 PGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_203 PGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFP 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB4 GPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_203 GPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHG 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB4 IPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_203 IPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGM 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB4 MGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_203 MGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLL 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB4 GSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_203 GSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLI 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB4 GPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_203 GPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPG 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB4 PKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_203 PKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPG 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KB4 NPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_203 NPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGL 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KB4 SGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_203 SGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPP 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 pF1KB4 GRPG------LPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRP :::: :::::::::::::::::::::::::::::::::::::::::::::::::: NP_203 GRPGPTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRP 1270 1280 1290 1300 1310 1320 1320 1330 1340 1350 1360 1370 pF1KB4 GLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_203 GLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGD 1330 1340 1350 1360 1370 1380 1380 1390 1400 1410 1420 1430 pF1KB4 AGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_203 AGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGT 1390 1400 1410 1420 1430 1440 1440 1450 1460 1470 1480 1490 pF1KB4 RGLDGPPGPDGLQGPPGPPGTSSVAHGFLITRHSQTTDAPQCPQGTLQVYEGFSLLYVQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_203 RGLDGPPGPDGLQGPPGPPGTSSVAHGFLITRHSQTTDAPQCPQGTLQVYEGFSLLYVQG 1450 1460 1470 1480 1490 1500 1500 1510 1520 1530 1540 1550 pF1KB4 NKRAHGQDLGTAGSCLRRFSTMPFMFCNINNVCNFASRNDYSYWLSTPEPMPMSMQPLKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_203 NKRAHGQDLGTAGSCLRRFSTMPFMFCNINNVCNFASRNDYSYWLSTPEPMPMSMQPLKG 1510 1520 1530 1540 1550 1560 1560 1570 1580 1590 1600 1610 pF1KB4 QSIQPFISRCAVCEAPAVVIAVHSQTIQIPHCPQGWDSLWIGYSFMMHTSAGAEGSGQAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_203 QSIQPFISRCAVCEAPAVVIAVHSQTIQIPHCPQGWDSLWIGYSFMMHTSAGAEGSGQAL 1570 1580 1590 1600 1610 1620 1620 1630 1640 1650 1660 1670 pF1KB4 ASPGSCLEEFRSAPFIECHGRGTCNYYANSYSFWLATVDVSDMFSKPQSETLKAGDLRTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_203 ASPGSCLEEFRSAPFIECHGRGTCNYYANSYSFWLATVDVSDMFSKPQSETLKAGDLRTR 1630 1640 1650 1660 1670 1680 1680 pF1KB4 ISRCQVCMKRT ::::::::::: NP_203 ISRCQVCMKRT 1690 >>XP_016884749 (OMIM: 301050,303630) PREDICTED: collagen (1690 aa) initn: 12720 init1: 12720 opt: 12720 Z-score: 4257.2 bits: 800.7 E(85289): 0 Smith-Waterman score: 12720; 100.0% identity (100.0% similar) in 1658 aa overlap (28-1685:33-1690) 10 20 30 40 50 pF1KB4 MKLRGVSLAAGLFLLALSLWGQPAEAAACYGCSPGSKCDCSGIKGEKGERGFPGLEG :::::::::::::::::::::::::::::: XP_016 VDSGKTENRDWEGFCYSTSAYWKNLYDGLLACYGCSPGSKCDCSGIKGEKGERGFPGLEG 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB4 HPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPG 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB4 PQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPG 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB4 PPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGP 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB4 PGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKR 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB4 GKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGE 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB4 KGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGIS 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB4 IPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDK 430 440 450 460 470 480 480 490 500 510 520 530 pF1KB4 GDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGA 490 500 510 520 530 540 540 550 560 570 580 590 pF1KB4 PGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGIT 550 560 570 580 590 600 600 610 620 630 640 650 pF1KB4 FKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQ 610 620 630 640 650 660 660 670 680 690 700 710 pF1KB4 TITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGF 670 680 690 700 710 720 720 730 740 750 760 770 pF1KB4 PGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDR 730 740 750 760 770 780 780 790 800 810 820 830 pF1KB4 GFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPG 790 800 810 820 830 840 840 850 860 870 880 890 pF1KB4 LHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGE 850 860 870 880 890 900 900 910 920 930 940 950 pF1KB4 MGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDP 910 920 930 940 950 960 960 970 980 990 1000 1010 pF1KB4 NLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQP 970 980 990 1000 1010 1020 1020 1030 1040 1050 1060 1070 pF1KB4 GLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPG 1030 1040 1050 1060 1070 1080 1080 1090 1100 1110 1120 1130 pF1KB4 LPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISG 1090 1100 1110 1120 1130 1140 1140 1150 1160 1170 1180 1190 pF1KB4 PPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGL 1150 1160 1170 1180 1190 1200 1200 1210 1220 1230 1240 1250 pF1KB4 PGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQ 1210 1220 1230 1240 1250 1260 1260 1270 1280 1290 1300 1310 pF1KB4 GPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLN 1270 1280 1290 1300 1310 1320 1320 1330 1340 1350 1360 1370 pF1KB4 GMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGP 1330 1340 1350 1360 1370 1380 1380 1390 1400 1410 1420 1430 pF1KB4 PGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGL 1390 1400 1410 1420 1430 1440 1440 1450 1460 1470 1480 1490 pF1KB4 DGPPGPDGLQGPPGPPGTSSVAHGFLITRHSQTTDAPQCPQGTLQVYEGFSLLYVQGNKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DGPPGPDGLQGPPGPPGTSSVAHGFLITRHSQTTDAPQCPQGTLQVYEGFSLLYVQGNKR 1450 1460 1470 1480 1490 1500 1500 1510 1520 1530 1540 1550 pF1KB4 AHGQDLGTAGSCLRRFSTMPFMFCNINNVCNFASRNDYSYWLSTPEPMPMSMQPLKGQSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AHGQDLGTAGSCLRRFSTMPFMFCNINNVCNFASRNDYSYWLSTPEPMPMSMQPLKGQSI 1510 1520 1530 1540 1550 1560 1560 1570 1580 1590 1600 1610 pF1KB4 QPFISRCAVCEAPAVVIAVHSQTIQIPHCPQGWDSLWIGYSFMMHTSAGAEGSGQALASP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QPFISRCAVCEAPAVVIAVHSQTIQIPHCPQGWDSLWIGYSFMMHTSAGAEGSGQALASP 1570 1580 1590 1600 1610 1620 1620 1630 1640 1650 1660 1670 pF1KB4 GSCLEEFRSAPFIECHGRGTCNYYANSYSFWLATVDVSDMFSKPQSETLKAGDLRTRISR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GSCLEEFRSAPFIECHGRGTCNYYANSYSFWLATVDVSDMFSKPQSETLKAGDLRTRISR 1630 1640 1650 1660 1670 1680 1680 pF1KB4 CQVCMKRT :::::::: XP_016 CQVCMKRT 1690 >>XP_016884748 (OMIM: 301050,303630) PREDICTED: collagen (1693 aa) initn: 10166 init1: 10166 opt: 12704 Z-score: 4251.9 bits: 799.8 E(85289): 0 Smith-Waterman score: 12704; 99.8% identity (99.8% similar) in 1661 aa overlap (28-1685:33-1693) 10 20 30 40 50 pF1KB4 MKLRGVSLAAGLFLLALSLWGQPAEAAACYGCSPGSKCDCSGIKGEKGERGFPGLEG :::::::::::::::::::::::::::::: XP_016 VDSGKTENRDWEGFCYSTSAYWKNLYDGLLACYGCSPGSKCDCSGIKGEKGERGFPGLEG 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB4 HPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPG 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB4 PQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPG 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB4 PPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGP 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB4 PGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKR 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB4 GKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGE 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB4 KGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGIS 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB4 IPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDK 430 440 450 460 470 480 480 490 500 510 520 530 pF1KB4 GDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGA 490 500 510 520 530 540 540 550 560 570 580 590 pF1KB4 PGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGIT 550 560 570 580 590 600 600 610 620 630 640 650 pF1KB4 FKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQ 610 620 630 640 650 660 660 670 680 690 700 710 pF1KB4 TITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGF 670 680 690 700 710 720 720 730 740 750 760 770 pF1KB4 PGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDR 730 740 750 760 770 780 780 790 800 810 820 830 pF1KB4 GFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPG 790 800 810 820 830 840 840 850 860 870 880 890 pF1KB4 LHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGE 850 860 870 880 890 900 900 910 920 930 940 950 pF1KB4 MGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDP 910 920 930 940 950 960 960 970 980 990 1000 1010 pF1KB4 NLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQP 970 980 990 1000 1010 1020 1020 1030 1040 1050 1060 1070 pF1KB4 GLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPG 1030 1040 1050 1060 1070 1080 1080 1090 1100 1110 1120 1130 pF1KB4 LPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISG 1090 1100 1110 1120 1130 1140 1140 1150 1160 1170 1180 1190 pF1KB4 PPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGL 1150 1160 1170 1180 1190 1200 1200 1210 1220 1230 1240 1250 pF1KB4 PGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQ 1210 1220 1230 1240 1250 1260 1260 1270 1280 1290 1300 1310 pF1KB4 GPPGRPG---LPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRP ::::::: :::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GPPGRPGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRP 1270 1280 1290 1300 1310 1320 1320 1330 1340 1350 1360 1370 pF1KB4 GLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGD 1330 1340 1350 1360 1370 1380 1380 1390 1400 1410 1420 1430 pF1KB4 AGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGT 1390 1400 1410 1420 1430 1440 1440 1450 1460 1470 1480 1490 pF1KB4 RGLDGPPGPDGLQGPPGPPGTSSVAHGFLITRHSQTTDAPQCPQGTLQVYEGFSLLYVQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RGLDGPPGPDGLQGPPGPPGTSSVAHGFLITRHSQTTDAPQCPQGTLQVYEGFSLLYVQG 1450 1460 1470 1480 1490 1500 1500 1510 1520 1530 1540 1550 pF1KB4 NKRAHGQDLGTAGSCLRRFSTMPFMFCNINNVCNFASRNDYSYWLSTPEPMPMSMQPLKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NKRAHGQDLGTAGSCLRRFSTMPFMFCNINNVCNFASRNDYSYWLSTPEPMPMSMQPLKG 1510 1520 1530 1540 1550 1560 1560 1570 1580 1590 1600 1610 pF1KB4 QSIQPFISRCAVCEAPAVVIAVHSQTIQIPHCPQGWDSLWIGYSFMMHTSAGAEGSGQAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QSIQPFISRCAVCEAPAVVIAVHSQTIQIPHCPQGWDSLWIGYSFMMHTSAGAEGSGQAL 1570 1580 1590 1600 1610 1620 1620 1630 1640 1650 1660 1670 pF1KB4 ASPGSCLEEFRSAPFIECHGRGTCNYYANSYSFWLATVDVSDMFSKPQSETLKAGDLRTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ASPGSCLEEFRSAPFIECHGRGTCNYYANSYSFWLATVDVSDMFSKPQSETLKAGDLRTR 1630 1640 1650 1660 1670 1680 1680 pF1KB4 ISRCQVCMKRT ::::::::::: XP_016 ISRCQVCMKRT 1690 >>XP_011529151 (OMIM: 301050,303630) PREDICTED: collagen (1696 aa) initn: 10074 init1: 10074 opt: 12698 Z-score: 4249.9 bits: 799.4 E(85289): 0 Smith-Waterman score: 12698; 99.6% identity (99.6% similar) in 1664 aa overlap (28-1685:33-1696) 10 20 30 40 50 pF1KB4 MKLRGVSLAAGLFLLALSLWGQPAEAAACYGCSPGSKCDCSGIKGEKGERGFPGLEG :::::::::::::::::::::::::::::: XP_011 VDSGKTENRDWEGFCYSTSAYWKNLYDGLLACYGCSPGSKCDCSGIKGEKGERGFPGLEG 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB4 HPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPG 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB4 PQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPG 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB4 PPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGP 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB4 PGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKR 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB4 GKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGE 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB4 KGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGIS 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB4 IPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDK 430 440 450 460 470 480 480 490 500 510 520 530 pF1KB4 GDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGA 490 500 510 520 530 540 540 550 560 570 580 590 pF1KB4 PGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGIT 550 560 570 580 590 600 600 610 620 630 640 650 pF1KB4 FKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQ 610 620 630 640 650 660 660 670 680 690 700 710 pF1KB4 TITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGF 670 680 690 700 710 720 720 730 740 750 760 770 pF1KB4 PGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDR 730 740 750 760 770 780 780 790 800 810 820 830 pF1KB4 GFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPG 790 800 810 820 830 840 840 850 860 870 880 890 pF1KB4 LHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGE 850 860 870 880 890 900 900 910 920 930 940 950 pF1KB4 MGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDP 910 920 930 940 950 960 960 970 980 990 1000 1010 pF1KB4 NLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQP 970 980 990 1000 1010 1020 1020 1030 1040 1050 1060 1070 pF1KB4 GLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPG 1030 1040 1050 1060 1070 1080 1080 1090 1100 1110 1120 1130 pF1KB4 LPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISG 1090 1100 1110 1120 1130 1140 1140 1150 1160 1170 1180 1190 pF1KB4 PPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGL 1150 1160 1170 1180 1190 1200 1200 1210 1220 1230 1240 1250 pF1KB4 PGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQ 1210 1220 1230 1240 1250 1260 1260 1270 1280 1290 1300 1310 pF1KB4 GPPGRPG------LPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNP ::::::: ::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GPPGRPGPTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNP 1270 1280 1290 1300 1310 1320 1320 1330 1340 1350 1360 1370 pF1KB4 GRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIII 1330 1340 1350 1360 1370 1380 1380 1390 1400 1410 1420 1430 pF1KB4 KGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQ 1390 1400 1410 1420 1430 1440 1440 1450 1460 1470 1480 1490 pF1KB4 PGTRGLDGPPGPDGLQGPPGPPGTSSVAHGFLITRHSQTTDAPQCPQGTLQVYEGFSLLY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PGTRGLDGPPGPDGLQGPPGPPGTSSVAHGFLITRHSQTTDAPQCPQGTLQVYEGFSLLY 1450 1460 1470 1480 1490 1500 1500 1510 1520 1530 1540 1550 pF1KB4 VQGNKRAHGQDLGTAGSCLRRFSTMPFMFCNINNVCNFASRNDYSYWLSTPEPMPMSMQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VQGNKRAHGQDLGTAGSCLRRFSTMPFMFCNINNVCNFASRNDYSYWLSTPEPMPMSMQP 1510 1520 1530 1540 1550 1560 1560 1570 1580 1590 1600 1610 pF1KB4 LKGQSIQPFISRCAVCEAPAVVIAVHSQTIQIPHCPQGWDSLWIGYSFMMHTSAGAEGSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LKGQSIQPFISRCAVCEAPAVVIAVHSQTIQIPHCPQGWDSLWIGYSFMMHTSAGAEGSG 1570 1580 1590 1600 1610 1620 1620 1630 1640 1650 1660 1670 pF1KB4 QALASPGSCLEEFRSAPFIECHGRGTCNYYANSYSFWLATVDVSDMFSKPQSETLKAGDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QALASPGSCLEEFRSAPFIECHGRGTCNYYANSYSFWLATVDVSDMFSKPQSETLKAGDL 1630 1640 1650 1660 1670 1680 1680 pF1KB4 RTRISRCQVCMKRT :::::::::::::: XP_011 RTRISRCQVCMKRT 1690 >>XP_016884750 (OMIM: 301050,303630) PREDICTED: collagen (1330 aa) initn: 11995 init1: 9750 opt: 9933 Z-score: 3331.0 bits: 629.0 E(85289): 8.5e-179 Smith-Waterman score: 9933; 99.5% identity (99.5% similar) in 1287 aa overlap (28-1308:33-1319) 10 20 30 40 50 pF1KB4 MKLRGVSLAAGLFLLALSLWGQPAEAAACYGCSPGSKCDCSGIKGEKGERGFPGLEG :::::::::::::::::::::::::::::: XP_016 VDSGKTENRDWEGFCYSTSAYWKNLYDGLLACYGCSPGSKCDCSGIKGEKGERGFPGLEG 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB4 HPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPG 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB4 PQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPG 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB4 PPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGP 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB4 PGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKR 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB4 GKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGE 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB4 KGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGIS 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB4 IPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDK 430 440 450 460 470 480 480 490 500 510 520 530 pF1KB4 GDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGA 490 500 510 520 530 540 540 550 560 570 580 590 pF1KB4 PGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGIT 550 560 570 580 590 600 600 610 620 630 640 650 pF1KB4 FKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQ 610 620 630 640 650 660 660 670 680 690 700 710 pF1KB4 TITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGF 670 680 690 700 710 720 720 730 740 750 760 770 pF1KB4 PGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDR 730 740 750 760 770 780 780 790 800 810 820 830 pF1KB4 GFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPG 790 800 810 820 830 840 840 850 860 870 880 890 pF1KB4 LHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGE 850 860 870 880 890 900 900 910 920 930 940 950 pF1KB4 MGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDP 910 920 930 940 950 960 960 970 980 990 1000 1010 pF1KB4 NLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQP 970 980 990 1000 1010 1020 1020 1030 1040 1050 1060 1070 pF1KB4 GLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPG 1030 1040 1050 1060 1070 1080 1080 1090 1100 1110 1120 1130 pF1KB4 LPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISG 1090 1100 1110 1120 1130 1140 1140 1150 1160 1170 1180 1190 pF1KB4 PPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGL 1150 1160 1170 1180 1190 1200 1200 1210 1220 1230 1240 1250 pF1KB4 PGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQ 1210 1220 1230 1240 1250 1260 1260 1270 1280 1290 1300 1310 pF1KB4 GPPGRPG------LPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNP ::::::: :::::::::::::::::::::::::::::::::::::::::::: XP_016 GPPGRPGPTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQWFD 1270 1280 1290 1300 1310 1320 1320 1330 1340 1350 1360 1370 pF1KB4 GRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIII XP_016 LIVQREIL 1330 >>XP_016884751 (OMIM: 301050,303630) PREDICTED: collagen (1289 aa) initn: 17720 init1: 9618 opt: 9619 Z-score: 3226.6 bits: 609.7 E(85289): 5.5e-173 Smith-Waterman score: 9619; 99.3% identity (99.4% similar) in 1249 aa overlap (28-1276:33-1279) 10 20 30 40 50 pF1KB4 MKLRGVSLAAGLFLLALSLWGQPAEAAACYGCSPGSKCDCSGIKGEKGERGFPGLEG :::::::::::::::::::::::::::::: XP_016 VDSGKTENRDWEGFCYSTSAYWKNLYDGLLACYGCSPGSKCDCSGIKGEKGERGFPGLEG 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB4 HPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPG 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB4 PQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPG 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB4 PPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGP 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB4 PGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKR 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB4 GKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGE 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB4 KGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGIS 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB4 IPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDK 430 440 450 460 470 480 480 490 500 510 520 530 pF1KB4 GDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGA 490 500 510 520 530 540 540 550 560 570 580 590 pF1KB4 PGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGIT 550 560 570 580 590 600 600 610 620 630 640 650 pF1KB4 FKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQ 610 620 630 640 650 660 660 670 680 690 700 710 pF1KB4 TITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGF 670 680 690 700 710 720 720 730 740 750 760 770 pF1KB4 PGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDR 730 740 750 760 770 780 780 790 800 810 820 830 pF1KB4 GFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPG 790 800 810 820 830 840 840 850 860 870 880 890 pF1KB4 LHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGE 850 860 870 880 890 900 900 910 920 930 940 950 pF1KB4 MGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDP 910 920 930 940 950 960 960 970 980 990 1000 1010 pF1KB4 NLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQP 970 980 990 1000 1010 1020 1020 1030 1040 1050 1060 1070 pF1KB4 GLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPG 1030 1040 1050 1060 1070 1080 1080 1090 1100 1110 1120 1130 pF1KB4 LPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISG 1090 1100 1110 1120 1130 1140 1140 1150 1160 1170 1180 1190 pF1KB4 PPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGL 1150 1160 1170 1180 1190 1200 1200 1210 1220 1230 1240 1250 pF1KB4 PGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQ 1210 1220 1230 1240 1250 1260 1260 1270 1280 1290 1300 1310 pF1KB4 GPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLN :::::::. ::. : XP_016 GPPGRPGFQTI--PPSHFGLSQSSQFYCC 1270 1280 >>XP_016884752 (OMIM: 301050,303630) PREDICTED: collagen (1136 aa) initn: 5975 init1: 5975 opt: 8599 Z-score: 2887.8 bits: 546.8 E(85289): 4.1e-154 Smith-Waterman score: 8599; 99.5% identity (99.5% similar) in 1136 aa overlap (556-1685:1-1136) 530 540 550 560 570 580 pF1KB4 KGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPG :::::::::::::::::::::::::::::: XP_016 MKGDKGELGSPGAPGLPGLPGTPGQDGLPG 10 20 30 590 600 610 620 630 640 pF1KB4 LPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQ 40 50 60 70 80 90 650 660 670 680 690 700 pF1KB4 PGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPG 100 110 120 130 140 150 710 720 730 740 750 760 pF1KB4 IGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLP 160 170 180 190 200 210 770 780 790 800 810 820 pF1KB4 GFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPG 220 230 240 250 260 270 830 840 850 860 870 880 pF1KB4 PPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGK 280 290 300 310 320 330 890 900 910 920 930 940 pF1KB4 AGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGE 340 350 360 370 380 390 950 960 970 980 990 1000 pF1KB4 PGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPP 400 410 420 430 440 450 1010 1020 1030 1040 1050 1060 pF1KB4 GPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDK 460 470 480 490 500 510 1070 1080 1090 1100 1110 1120 pF1KB4 GDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPG 520 530 540 550 560 570 1130 1140 1150 1160 1170 1180 pF1KB4 TPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPG 580 590 600 610 620 630 1190 1200 1210 1220 1230 1240 pF1KB4 QPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGP 640 650 660 670 680 690 1250 1260 1270 1280 1290 pF1KB4 ALEGPKGNPGPQGPPGRPG------LPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLK ::::::::::::::::::: ::::::::::::::::::::::::::::::::::: XP_016 ALEGPKGNPGPQGPPGRPGPTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLK 700 710 720 730 740 750 1300 1310 1320 1330 1340 1350 pF1KB4 GDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPP 760 770 780 790 800 810 1360 1370 1380 1390 1400 1410 pF1KB4 GLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGA 820 830 840 850 860 870 1420 1430 1440 1450 1460 1470 pF1KB4 GGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPGTSSVAHGFLITRHSQTTDAPQCPQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPGTSSVAHGFLITRHSQTTDAPQCPQG 880 890 900 910 920 930 1480 1490 1500 1510 1520 1530 pF1KB4 TLQVYEGFSLLYVQGNKRAHGQDLGTAGSCLRRFSTMPFMFCNINNVCNFASRNDYSYWL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TLQVYEGFSLLYVQGNKRAHGQDLGTAGSCLRRFSTMPFMFCNINNVCNFASRNDYSYWL 940 950 960 970 980 990 1540 1550 1560 1570 1580 1590 pF1KB4 STPEPMPMSMQPLKGQSIQPFISRCAVCEAPAVVIAVHSQTIQIPHCPQGWDSLWIGYSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 STPEPMPMSMQPLKGQSIQPFISRCAVCEAPAVVIAVHSQTIQIPHCPQGWDSLWIGYSF 1000 1010 1020 1030 1040 1050 1600 1610 1620 1630 1640 1650 pF1KB4 MMHTSAGAEGSGQALASPGSCLEEFRSAPFIECHGRGTCNYYANSYSFWLATVDVSDMFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MMHTSAGAEGSGQALASPGSCLEEFRSAPFIECHGRGTCNYYANSYSFWLATVDVSDMFS 1060 1070 1080 1090 1100 1110 1660 1670 1680 pF1KB4 KPQSETLKAGDLRTRISRCQVCMKRT :::::::::::::::::::::::::: XP_016 KPQSETLKAGDLRTRISRCQVCMKRT 1120 1130 >>NP_001836 (OMIM: 120130,175780,180000,607595,611773,61 (1669 aa) initn: 5726 init1: 3511 opt: 7031 Z-score: 2364.2 bits: 450.5 E(85289): 6e-125 Smith-Waterman score: 7535; 61.4% identity (73.7% similar) in 1704 aa overlap (5-1685:2-1669) 10 20 30 40 50 pF1KB4 MKLRGVSLAAGLFLL--ALSLWGQPAEAAACYGCSPGS---KCDCSGIKGEKGERGFPGL : :.. :.:: :: : . ..::: ::. :: :::: :.::.:::::.::: NP_001 MGPRLSVWLLLLPAALLLHEEHSRAAAKGGCA-GSGCGKCDCHGVKGQKGERGLPGL 10 20 30 40 50 60 70 80 90 100 110 pF1KB4 EGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGA .: :.::. ::::: :: ::::: : :: :: :: ::::: :.::.:::::.::.:: NP_001 QGVIGFPGMQGPEGPQGPPGQKGDTGEPGLPGTKGTRGPPGASGYPGNPGLPGIPGQDGP 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB4 PGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGP--KGNP ::: ::::::::::::: : ::.::. : :::::.:::::.:: : .. .:: ::. NP_001 PGPPGIPGCNGTKGERGPLGPPGLPGFAGNPGPPGLPGMKGDPGEI-LGHVPGMLLKGER 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB4 GYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQG :.:: :: : :: :. ::.:::: : ::::::: :: ::.:::.::::::.::.:: NP_001 GFPGIPGTPGPPGLPGLQGPVGPPGFTGPPGPPGPPGPPGEKGQMGLSFQGPKGDKGDQG 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB4 LQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGE ..:::: ::: . : .::: . :..: : ::..: :: ::::: :. NP_001 VSGPPGVPGQAQVQ--------EKGDFATKGEKGQKGEPGFQGMPGV-----GEKGEPGK 240 250 260 270 280 300 310 320 330 340 350 pF1KB4 PGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGI :: ::::::::..:. : ::.::.::::: ::.: .:.::..:::::::.:: ::: NP_001 PGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGRQGPQGEKGEAGPPGPPGIVI---GTG- 290 300 310 320 330 360 370 380 390 400 410 pF1KB4 TIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGP .::::. : :: :: .:: : :. : :: ::::: : : : ::::::::.:::.: NP_001 PLGEKGERGYPGTPGPRGEPGPKGFPGLPGQPGPPGLPVPGQAGAPGFPGERGEKGDRGF 340 350 360 370 380 390 420 430 440 450 460 470 pF1KB4 PGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPG---PPGSPGDKGLQGE :: :.::: : :: :: :: ::::: : . :.::::: ::: ::. :. :: NP_001 PGTSLPGPSGRDGLPGPPGSPGPPGQPGYTNGIVE--CQPGPPGDQGPPGIPGQPGFIGE 400 410 420 430 440 450 480 490 500 510 520 530 pF1KB4 QGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPG : ::.::..:. : : :::: : :::: .::::: : ::. : : :. : NP_001 IGEKGQKGESCLICDIDGYRGPPG-P-----QGPPGEIGFPGQPGAKGDRGLPGRDGVAG 460 470 480 490 500 510 540 550 560 570 580 pF1KB4 IPGAPGAPGF---PGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLP .:: :.::. ::.:::::.. .:::::. : :: ::.:: :.::.:: :::: NP_001 VPGPQGTPGLIGQPGAKGEPGEFYFDLRLKGDKGDPGFPGQPGMPGRAGSPGRDGHPGLP 520 530 540 550 560 570 590 600 610 620 630 640 pF1KB4 GPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPG :::: ::.. .::::::::. :.:: :. :: ::::.:: ::.:.:: : :.::.:: NP_001 GPKGSPGSVGLKGERGPPGGVGFPGSRGDTGPPGPPGYGPAGPIGDKGQAGFPGGPGSPG 580 590 600 610 620 630 650 660 670 680 690 700 pF1KB4 IPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIG .:::::.::. . :: :: : :: : : :: :.:: :: ::.:: :: : :::: NP_001 LPGPKGEPGKIVPLPGPPGAEGLPGSPGFPGPQGDRGFPGTPGRPGLPGEKGAVGQPGIG 640 650 660 670 680 690 710 720 730 740 750 760 pF1KB4 LPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGF .:::::::: :.:: : :::::: :..: :: :: : ::::: .::: : :::::. NP_001 FPGPPGPKGVDGLPGDMGPPGTPGRPGFNGLPGNPGVQGQKGEPGVGLPGLKGLPGLPGI 700 710 720 730 740 750 770 780 790 800 810 820 pF1KB4 KGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPP :. : ::. : :: :: : : :: : .:. :: : :: .: ::.:::: : ::: NP_001 PGTPGEKGSIGVPGVPGEHGAIGPPGLQGIRGEPGPPGLPGSVGSPGVPGIGPPGARGPP 760 770 780 790 800 810 830 840 850 860 870 880 pF1KB4 GIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAG : :: : : :: :::: :: ::::.::: :..:. :.:: : : :: :: : : NP_001 GGQGPPGLSGPPGIKGEKGFPGFPGLDMPGPKGDKGAQGLPGITGQSGLPGLPGQQGAPG 820 830 840 850 860 870 890 900 910 920 930 940 pF1KB4 ASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPG ::::.:::::.:: :: :: : : :.:: ::: :. :. : : : ::.::. : NP_001 IPGFPGSKGEMGVMGTPGQPGSPGPVGAPGLPGEKGDHGFPGSSGPRGDPGLKGDKGDVG 880 890 900 910 920 930 950 960 970 980 990 1000 pF1KB4 LPGPPGPMDPNLLGS-KGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPG ::: :: :: .:: ::.::. : : : : :: .: :: :: :: .:: : :: :: NP_001 LPGKPGSMDKVDMGSMKGQKGDQGEKGQIGPIGEKGSRGDPGTPGVPGKDGQAGQPGQPG 940 950 960 970 980 990 1010 1020 1030 1040 1050 1060 pF1KB4 PKGNPGLPGQPGLIGPPGLKGTIGDMGFPG-P--QGVEGPPGPSGVPGQPGSPGLPGQKG :::.::. : :: : :: ::..: ::.:: : .:: : :::.: :: ::. : :.:: NP_001 PKGDPGISGTPGAPGLPGPKGSVGGMGLPGTPGEKGVPGIPGPQGSPGLPGDKGAKGEKG 1000 1010 1020 1030 1040 1050 1070 1080 1090 1100 1110 1120 pF1KB4 DKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGF . : ::: :.::: : ::. :. :.::.:: :: :. :.::.::.:: ::.:: :. NP_001 QAGPPGI---GIPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIPGMPGSPGLKGSPGSVGY 1060 1070 1080 1090 1100 1130 1140 1150 1160 1170 1180 pF1KB4 PGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGE ::.:: :: :: .: :: :.:: : .: : :: :: :.::.::.::::: ::.::: NP_001 PGSPGLPGEKGDKGLPGLDGIPGVKGEAGLPGTPGPTGPAGQKGEPGSDGIPGSAGEKGE 1110 1120 1130 1140 1150 1160 1190 1200 1210 1220 1230 1240 pF1KB4 PGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSP :: :: : :: :: : .:.::. :.::. :.::.:: ::: :: : :: :: :: :::: NP_001 PGLPGRGFPGFPGAKGDKGSKGEVGFPGLAGSPGIPGSKGEQGFMGPPGPQGQPGLPGSP 1170 1180 1190 1200 1210 1220 1250 1260 1270 1280 1290 1300 pF1KB4 GPALEGPKGNPGPQGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQG : : :::::. :::: :: :::::: ::::::: :.::.::::: :: ::.:: ::: : NP_001 GHATEGPKGDRGPQGQPGLPGLPGPMGPPGLPGIDGVKGDKGNPGWPGAPGVPGPKGDPG 1230 1240 1250 1260 1270 1280 1310 1320 1330 1340 1350 1360 pF1KB4 PPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKG-PS--GVPGSAGPEGEPGLIGPPGPPG :. : : ::..: ::: : :::::: : :: :. :. :. : .: :: : ::::: NP_001 FQGMPGIGGSPGITGSKGDMGPPGVPGFQGPKGLPGLQGIKGDQGDQGVPGAKGLPGPPG 1290 1300 1310 1320 1330 1340 1370 1380 1390 1400 1410 pF1KB4 LPGPSGQSIIIKGDAGPPGIPGQPGLKGL---PGPQGPQGLPGPTGPPGDPGRNGLPGFD ::: ::::. : :: : :::::: :::.: ::. : .: :: : :.:::: NP_001 PPGPYD---IIKGEPGLPGPEGPPGLKGLQGLPGPKGQQGVTGLVGIPGPP---GIPGFD 1350 1360 1370 1380 1390 1400 1420 1430 1440 1450 1460 1470 pF1KB4 GAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPGTSSVAHGFLITRHSQTTDAPQCP :: :.::. : : : ::. :::::::: : ::::: :: ::::.:::::: : :::: NP_001 GAPGQKGEMGPAGPTGPRGFPGPPGPDGLPGSMGPPGTPSVDHGFLVTRHSQTIDDPQCP 1410 1420 1430 1440 1450 1460 1480 1490 1500 1510 1520 1530 pF1KB4 QGTLQVYEGFSLLYVQGNKRAHGQDLGTAGSCLRRFSTMPFMFCNINNVCNFASRNDYSY .:: .:.:.::::::::.:::::::::::::::.::::::.:::::::::::::::::: NP_001 SGTKILYHGYSLLYVQGNERAHGQDLGTAGSCLRKFSTMPFLFCNINNVCNFASRNDYSY 1470 1480 1490 1500 1510 1520 1540 1550 1560 1570 1580 1590 pF1KB4 WLSTPEPMPMSMQPLKGQSIQPFISRCAVCEAPAVVIAVHSQTIQIPHCPQGWDSLWIGY :::::::::::: :. :..:.:::::::::::::.:.:::::::::: ::.::.:::::: NP_001 WLSTPEPMPMSMAPITGENIRPFISRCAVCEAPAMVMAVHSQTIQIPPCPSGWSSLWIGY 1530 1540 1550 1560 1570 1580 1600 1610 1620 1630 1640 1650 pF1KB4 SFMMHTSAGAEGSGQALASPGSCLEEFRSAPFIECHGRGTCNYYANSYSFWLATVDVSDM ::.:::::::::::::::::::::::::::::::::::::::::::.:::::::.. :.: NP_001 SFVMHTSAGAEGSGQALASPGSCLEEFRSAPFIECHGRGTCNYYANAYSFWLATIERSEM 1590 1600 1610 1620 1630 1640 1660 1670 1680 pF1KB4 FSKPQSETLKAGDLRTRISRCQVCMKRT :.:: :::::.:::..:::::::.:: NP_001 FKKPTPSTLKAGELRTHVSRCQVCMRRT 1650 1660 >>XP_011519350 (OMIM: 120130,175780,180000,607595,611773 (1605 aa) initn: 5688 init1: 3511 opt: 6965 Z-score: 2342.4 bits: 446.4 E(85289): 9.8e-124 Smith-Waterman score: 7348; 61.8% identity (73.8% similar) in 1638 aa overlap (66-1685:3-1605) 40 50 60 70 80 90 pF1KB4 SKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPP ::::: :: ::::: : :: :: :: :::: XP_011 MQGPEGPQGPPGQKGDTGEPGLPGTKGTRGPP 10 20 30 100 110 120 130 140 150 pF1KB4 GLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMK : :.::.:::::.::.:: ::: ::::::::::::: : ::.::. : :::::.:::: XP_011 GASGYPGNPGLPGIPGQDGPPGPPGIPGCNGTKGERGPLGPPGLPGFAGNPGPPGLPGMK 40 50 60 70 80 90 160 170 180 190 200 210 pF1KB4 GEPGSIIMSSLPGP--KGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPG :.:: : .. .:: ::. :.:: :: : :: :. ::.:::: : ::::::: :: XP_011 GDPGEI-LGHVPGMLLKGERGFPGIPGTPGPPGLPGLQGPVGPPGFTGPPGPPGPPGPPG 100 110 120 130 140 150 220 230 240 250 260 270 pF1KB4 PKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPG ::.:::.::::::.::.::..:::: ::: . : .::: . :..: : :: XP_011 EKGQMGLSFQGPKGDKGDQGVSGPPGVPGQAQVQ--------EKGDFATKGEKGQKGEPG 160 170 180 190 200 280 290 300 310 320 330 pF1KB4 IRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQK ..: :: ::::: :.:: ::::::::..:. : ::.::.::::: ::.: .:.: XP_011 FQGMPGV-----GEKGEPGKPGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGRQGPQGEK 210 220 230 240 250 340 350 360 370 380 390 pF1KB4 GDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVM :..:::::::.:: ::: .::::. : :: :: .:: : :. : :: ::::: : XP_011 GEAGPPGPPGIVI---GTG-PLGEKGERGYPGTPGPRGEPGPKGFPGLPGQPGPPGLPVP 260 270 280 290 300 310 400 410 420 430 440 450 pF1KB4 GPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEP : : ::::::::.:::.: :: :.::: : :: :: :: ::::: : . :.: XP_011 GQAGAPGFPGERGEKGDRGFPGTSLPGPSGRDGLPGPPGSPGPPGQPGYTNGIVE--CQP 320 330 340 350 360 370 460 470 480 490 500 510 pF1KB4 GPPG---PPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGF :::: ::: ::. :. :: : ::.::..:. : : :::: : :::: .:: XP_011 GPPGDQGPPGIPGQPGFIGEIGEKGQKGESCLICDIDGYRGPPG-P-----QGPPGEIGF 380 390 400 410 420 520 530 540 550 560 pF1KB4 PGQKGEKGQAGATGPKGLPGIPGAPGAPGF---PGSKGEPGDILTFPGMKGDKGELGSPG ::: : ::. : : :. :.:: :.::. ::.:::::.. .:::::. : :: XP_011 PGQPGAKGDRGLPGRDGVAGVPGPQGTPGLIGQPGAKGEPGEFYFDLRLKGDKGDPGFPG 430 440 450 460 470 480 570 580 590 600 610 620 pF1KB4 APGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGP ::.:: :.::.:: :::::::: ::.. .::::::::. :.:: :. :: ::::.:: XP_011 QPGMPGRAGSPGRDGHPGLPGPKGSPGSVGLKGERGPPGGVGFPGSRGDTGPPGPPGYGP 490 500 510 520 530 540 630 640 650 660 670 680 pF1KB4 PGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPG ::.:.:: : :.::.::.:::::.::. . :: :: : :: : : :: :.:: XP_011 AGPIGDKGQAGFPGGPGSPGLPGPKGEPGKIVPLPGPPGAEGLPGSPGFPGPQGDRGFPG 550 560 570 580 590 600 690 700 710 720 730 740 pF1KB4 QPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGP :: ::.:: :: : ::::.:::::::: :.:: : :::::: :..: :: :: : XP_011 TPGRPGLPGEKGAVGQPGIGFPGPPGPKGVDGLPGDMGPPGTPGRPGFNGLPGNPGVQGQ 610 620 630 640 650 660 750 760 770 780 790 800 pF1KB4 KGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQP ::::: .::: : :::::. :. : ::. : :: :: : : :: : .:. :: : : XP_011 KGEPGVGLPGLKGLPGLPGIPGTPGEKGSIGVPGVPGEHGAIGPPGLQGIRGEPGPPGLP 670 680 690 700 710 720 810 820 830 840 850 860 pF1KB4 GPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGI : .: ::.:::: : :::: :: : : :: :::: :: ::::.::: :..:. :. XP_011 GSVGSPGVPGIGPPGARGPPGGQGPPGLSGPPGIKGEKGFPGFPGLDMPGPKGDKGAQGL 730 740 750 760 770 780 870 880 890 900 910 920 pF1KB4 PGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGL :: : : :: :: : : ::::.:::::.:: :: :: : : :.:: ::: :. XP_011 PGITGQSGLPGLPGQQGAPGIPGFPGSKGEMGVMGTPGQPGSPGPVGAPGLPGEKGDHGF 790 800 810 820 830 840 930 940 950 960 970 980 pF1KB4 QGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGS-KGEKGEPGLPGIPGVSGPKGYQGL :. : : : ::.::. :::: :: :: .:: ::.::. : : : : :: .: XP_011 PGSSGPRGDPGLKGDKGDVGLPGKPGSMDKVDMGSMKGQKGDQGEKGQIGPIGEKGSRGD 850 860 870 880 890 900 990 1000 1010 1020 1030 1040 pF1KB4 PGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPG-P--QGVEGP :: :: :: .:: : :: :::::.::. : :: : :: ::..: ::.:: : .:: : XP_011 PGTPGVPGKDGQAGQPGQPGPKGDPGISGTPGAPGLPGPKGSVGGMGLPGTPGEKGVPGI 910 920 930 940 950 960 1050 1060 1070 1080 1090 1100 pF1KB4 PGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDP :::.: :: ::. : :.::. : ::: :.::: : ::. :. :.::.:: :: :. XP_011 PGPQGSPGLPGDKGAKGEKGQAGPPGI---GIPGLRGEKGDQGIAGFPGSPGEKGEKGSI 970 980 990 1000 1010 1020 1110 1120 1130 1140 1150 1160 pF1KB4 GLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPP :.::.::.:: ::.:: :.::.:: :: :: .: :: :.:: : .: : :: :: XP_011 GIPGMPGSPGLKGSPGSVGYPGSPGLPGEKGDKGLPGLDGIPGVKGEAGLPGTPGPTGPA 1030 1040 1050 1060 1070 1080 1170 1180 1190 1200 1210 1220 pF1KB4 GEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKG :.::.::.::::: ::.::::: :: : :: :: : .:.::. :.::. :.::.:: :: XP_011 GQKGEPGSDGIPGSAGEKGEPGLPGRGFPGFPGAKGDKGSKGEVGFPGLAGSPGIPGSKG 1090 1100 1110 1120 1130 1140 1230 1240 1250 1260 1270 1280 pF1KB4 EPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGLPGPEGPPGLPGNGGIKGE : :: : :: :: :: ::::: : :::::. :::: :: :::::: ::::::: :.::. XP_011 EQGFMGPPGPQGQPGLPGSPGHATEGPKGDRGPQGQPGLPGLPGPMGPPGLPGIDGVKGD 1150 1160 1170 1180 1190 1200 1290 1300 1310 1320 1330 1340 pF1KB4 KGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKG-PS--GV ::::: :: ::.:: ::: : :. : : ::..: ::: : :::::: : :: :. :. XP_011 KGNPGWPGAPGVPGPKGDPGFQGMPGIGGSPGITGSKGDMGPPGVPGFQGPKGLPGLQGI 1210 1220 1230 1240 1250 1260 1350 1360 1370 1380 1390 pF1KB4 PGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGL---PGPQGPQG :. : .: :: : ::::: ::: ::::. : :: : :::::: :::.: :: XP_011 KGDQGDQGVPGAKGLPGPPGPPGPYD---IIKGEPGLPGPEGPPGLKGLQGLPGPKGQQG 1270 1280 1290 1300 1310 1320 1400 1410 1420 1430 1440 1450 pF1KB4 LPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPGTSS . : .: :: :: .:::::: :.::. : : : ::. :::::::: : ::::: : XP_011 VTGLVGIPGPPG---IPGFDGAPGQKGEMGPAGPTGPRGFPGPPGPDGLPGSMGPPGTPS 1330 1340 1350 1360 1370 1460 1470 1480 1490 1500 1510 pF1KB4 VAHGFLITRHSQTTDAPQCPQGTLQVYEGFSLLYVQGNKRAHGQDLGTAGSCLRRFSTMP : ::::.:::::: : ::::.:: .:.:.::::::::.:::::::::::::::.::::: XP_011 VDHGFLVTRHSQTIDDPQCPSGTKILYHGYSLLYVQGNERAHGQDLGTAGSCLRKFSTMP 1380 1390 1400 1410 1420 1430 1520 1530 1540 1550 1560 1570 pF1KB4 FMFCNINNVCNFASRNDYSYWLSTPEPMPMSMQPLKGQSIQPFISRCAVCEAPAVVIAVH :.:::::::::::::::::::::::::::::: :. :..:.:::::::::::::.:.::: XP_011 FLFCNINNVCNFASRNDYSYWLSTPEPMPMSMAPITGENIRPFISRCAVCEAPAMVMAVH 1440 1450 1460 1470 1480 1490 1580 1590 1600 1610 1620 1630 pF1KB4 SQTIQIPHCPQGWDSLWIGYSFMMHTSAGAEGSGQALASPGSCLEEFRSAPFIECHGRGT ::::::: ::.::.::::::::.::::::::::::::::::::::::::::::::::::: XP_011 SQTIQIPPCPSGWSSLWIGYSFVMHTSAGAEGSGQALASPGSCLEEFRSAPFIECHGRGT 1500 1510 1520 1530 1540 1550 1640 1650 1660 1670 1680 pF1KB4 CNYYANSYSFWLATVDVSDMFSKPQSETLKAGDLRTRISRCQVCMKRT ::::::.:::::::.. :.::.:: :::::.:::..:::::::.:: XP_011 CNYYANAYSFWLATIERSEMFKKPTPSTLKAGELRTHVSRCQVCMRRT 1560 1570 1580 1590 1600 1685 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Nov 2 22:54:56 2016 done: Wed Nov 2 22:54:59 2016 Total Scan time: 16.530 Total Display time: 0.820 Function used was FASTA [36.3.4 Apr, 2011]