FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB4489, 467 aa 1>>>pF1KB4489 467 - 467 aa - 467 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 10.7246+/-0.000389; mu= -7.5420+/- 0.024 mean_var=252.7294+/-51.135, 0's: 0 Z-trim(120.8): 44 B-trim: 0 in 0/57 Lambda= 0.080676 statistics sampled from 36539 (36583) to 36539 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.763), E-opt: 0.2 (0.429), width: 16 Scan time: 10.010 The best scores are: opt bits E(85289) NP_001120689 (OMIM: 603295,615342) mothers against ( 467) 3298 396.9 6.4e-110 XP_006719890 (OMIM: 603295,615342) PREDICTED: moth ( 479) 2949 356.2 1.1e-97 XP_011530266 (OMIM: 601595) PREDICTED: mothers aga ( 465) 2642 320.5 6.1e-87 XP_005263049 (OMIM: 601595) PREDICTED: mothers aga ( 465) 2642 320.5 6.1e-87 XP_011530264 (OMIM: 601595) PREDICTED: mothers aga ( 465) 2642 320.5 6.1e-87 NP_001003688 (OMIM: 601595) mothers against decape ( 465) 2642 320.5 6.1e-87 NP_005891 (OMIM: 601595) mothers against decapenta ( 465) 2642 320.5 6.1e-87 XP_006714280 (OMIM: 601595) PREDICTED: mothers aga ( 465) 2642 320.5 6.1e-87 XP_011530263 (OMIM: 601595) PREDICTED: mothers aga ( 465) 2642 320.5 6.1e-87 XP_011530265 (OMIM: 601595) PREDICTED: mothers aga ( 465) 2642 320.5 6.1e-87 XP_016864959 (OMIM: 603110) PREDICTED: mothers aga ( 465) 2584 313.7 6.6e-85 NP_001001419 (OMIM: 603110) mothers against decape ( 465) 2584 313.7 6.6e-85 NP_005894 (OMIM: 603110) mothers against decapenta ( 465) 2584 313.7 6.6e-85 NP_001001420 (OMIM: 603110) mothers against decape ( 465) 2584 313.7 6.6e-85 NP_005896 (OMIM: 603295,615342) mothers against de ( 430) 1599 199.1 2e-50 XP_005266458 (OMIM: 603295,615342) PREDICTED: moth ( 442) 1599 199.1 2.1e-50 XP_005266460 (OMIM: 603295,615342) PREDICTED: moth ( 393) 1358 171.0 5.2e-42 NP_005892 (OMIM: 601366) mothers against decapenta ( 467) 1320 166.6 1.3e-40 XP_006722514 (OMIM: 601366) PREDICTED: mothers aga ( 467) 1320 166.6 1.3e-40 NP_001003652 (OMIM: 601366) mothers against decape ( 467) 1320 166.6 1.3e-40 XP_005258316 (OMIM: 601366) PREDICTED: mothers aga ( 467) 1320 166.6 1.3e-40 XP_016881234 (OMIM: 601366) PREDICTED: mothers aga ( 467) 1320 166.6 1.3e-40 XP_016881237 (OMIM: 601366) PREDICTED: mothers aga ( 414) 1161 148.1 4.3e-35 XP_011524287 (OMIM: 601366) PREDICTED: mothers aga ( 414) 1161 148.1 4.3e-35 XP_016881236 (OMIM: 601366) PREDICTED: mothers aga ( 418) 1161 148.1 4.3e-35 XP_011524286 (OMIM: 601366) PREDICTED: mothers aga ( 425) 1161 148.1 4.4e-35 NP_001129409 (OMIM: 601366) mothers against decape ( 437) 1161 148.1 4.5e-35 XP_016881235 (OMIM: 601366) PREDICTED: mothers aga ( 437) 1161 148.1 4.5e-35 NP_001138574 (OMIM: 603109,613795) mothers against ( 320) 1153 147.1 6.6e-35 XP_011519862 (OMIM: 603109,613795) PREDICTED: moth ( 376) 1153 147.2 7.6e-35 NP_001138575 (OMIM: 603109,613795) mothers against ( 381) 1153 147.2 7.6e-35 NP_005893 (OMIM: 603109,613795) mothers against de ( 425) 1153 147.2 8.4e-35 XP_011519861 (OMIM: 603109,613795) PREDICTED: moth ( 381) 1125 143.9 7.3e-34 XP_016881239 (OMIM: 601366) PREDICTED: mothers aga ( 227) 1119 143.1 7.6e-34 NP_001138576 (OMIM: 603109,613795) mothers against ( 230) 1113 142.4 1.2e-33 XP_005266461 (OMIM: 603295,615342) PREDICTED: moth ( 356) 1109 142.0 2.5e-33 XP_016881238 (OMIM: 601366) PREDICTED: mothers aga ( 263) 518 73.2 9.8e-13 NP_005350 (OMIM: 139210,174900,175050,260350,60099 ( 552) 493 70.4 1.4e-11 NP_005576 (OMIM: 602931,614823) mothers against de ( 496) 365 55.5 3.9e-07 XP_011519863 (OMIM: 602931,614823) PREDICTED: moth ( 235) 344 52.9 1.1e-06 NP_001177751 (OMIM: 602932,612229) mothers against ( 211) 300 47.8 3.5e-05 NP_001177752 (OMIM: 602932,612229) mothers against ( 238) 300 47.8 3.9e-05 >>NP_001120689 (OMIM: 603295,615342) mothers against dec (467 aa) initn: 3298 init1: 3298 opt: 3298 Z-score: 2094.4 bits: 396.9 E(85289): 6.4e-110 Smith-Waterman score: 3298; 100.0% identity (100.0% similar) in 467 aa overlap (1-467:1-467) 10 20 30 40 50 60 pF1KB4 MHSTTPISSLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDSLVKKLKKKKGAMDELERALS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MHSTTPISSLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDSLVKKLKKKKGAMDELERALS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 CPGQPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CPGQPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 QKEVCINPYHYRRVETPVLPPVLVPRHSEYNPQLSLLAKFRSASLHSEPLMPHNATYPDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QKEVCINPYHYRRVETPVLPPVLVPRHSEYNPQLSLLAKFRSASLHSEPLMPHNATYPDS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 FQQPPCSALPPSPSHAFSQSPCTASYPHSPGSPSEPESPYQHSVDTPPLPYHATEASETQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FQQPPCSALPPSPSHAFSQSPCTASYPHSPGSPSEPESPYQHSVDTPPLPYHATEASETQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 SGQPVDATADRHVVLSIPNGDFRPVCYEEPQHWCSVAYYELNNRVGETFQASSRSVLIDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SGQPVDATADRHVVLSIPNGDFRPVCYEEPQHWCSVAYYELNNRVGETFQASSRSVLIDG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 FTDPSNNRNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECVSDSSIFVQSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FTDPSNNRNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECVSDSSIFVQSR 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB4 NCNYQHGFHPATVCKIPSGCSLKVFNNQLFAQLLAQSVHHGFEVVYELTKMCTIRMSFVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NCNYQHGFHPATVCKIPSGCSLKVFNNQLFAQLLAQSVHHGFEVVYELTKMCTIRMSFVK 370 380 390 400 410 420 430 440 450 460 pF1KB4 GWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS ::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS 430 440 450 460 >>XP_006719890 (OMIM: 603295,615342) PREDICTED: mothers (479 aa) initn: 2949 init1: 2949 opt: 2949 Z-score: 1874.7 bits: 356.2 E(85289): 1.1e-97 Smith-Waterman score: 2949; 100.0% identity (100.0% similar) in 420 aa overlap (1-420:1-420) 10 20 30 40 50 60 pF1KB4 MHSTTPISSLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDSLVKKLKKKKGAMDELERALS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MHSTTPISSLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDSLVKKLKKKKGAMDELERALS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 CPGQPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 CPGQPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 QKEVCINPYHYRRVETPVLPPVLVPRHSEYNPQLSLLAKFRSASLHSEPLMPHNATYPDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QKEVCINPYHYRRVETPVLPPVLVPRHSEYNPQLSLLAKFRSASLHSEPLMPHNATYPDS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 FQQPPCSALPPSPSHAFSQSPCTASYPHSPGSPSEPESPYQHSVDTPPLPYHATEASETQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FQQPPCSALPPSPSHAFSQSPCTASYPHSPGSPSEPESPYQHSVDTPPLPYHATEASETQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 SGQPVDATADRHVVLSIPNGDFRPVCYEEPQHWCSVAYYELNNRVGETFQASSRSVLIDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SGQPVDATADRHVVLSIPNGDFRPVCYEEPQHWCSVAYYELNNRVGETFQASSRSVLIDG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 FTDPSNNRNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECVSDSSIFVQSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FTDPSNNRNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECVSDSSIFVQSR 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB4 NCNYQHGFHPATVCKIPSGCSLKVFNNQLFAQLLAQSVHHGFEVVYELTKMCTIRMSFVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 NCNYQHGFHPATVCKIPSGCSLKVFNNQLFAQLLAQSVHHGFEVVYELTKMCTIRMSFVK 370 380 390 400 410 420 430 440 450 460 pF1KB4 GWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS XP_006 VAMKAGEPRKFLSGKERQLGLYMEVKAFSFITCYFVCCKVLANESSISKYGLIKVSGYV 430 440 450 460 470 >>XP_011530266 (OMIM: 601595) PREDICTED: mothers against (465 aa) initn: 2637 init1: 1354 opt: 2642 Z-score: 1681.8 bits: 320.5 E(85289): 6.1e-87 Smith-Waterman score: 2642; 81.5% identity (90.8% similar) in 465 aa overlap (7-467:3-465) 10 20 30 40 50 60 pF1KB4 MHSTTPISSLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDSLVKKLKKKKGAMDELERALS ..:::::::::::::::::::::::::::::::.::::::::::::.:::.::: XP_011 MNVTSLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDALVKKLKKKKGAMEELEKALS 10 20 30 40 50 70 80 90 100 110 120 pF1KB4 CPGQPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSK ::::::.::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CPGQPSNCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSK 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB4 QKEVCINPYHYRRVETPVLPPVLVPRHSEYNPQLSLLAKFRSASLHSEPLMPHNATYPDS :::::::::::.:::.::::::::::::::::: ::::.::. . ..:: :: :::.::: XP_011 QKEVCINPYHYKRVESPVLPPVLVPRHSEYNPQHSLLAQFRNLG-QNEPHMPLNATFPDS 120 130 140 150 160 170 190 200 210 220 230 pF1KB4 FQQPPCSALPPSPSHAFSQSPCTAS--YPHSPGSPSEPESPYQHSVDTPPLPYHATEASE :::: .: ::. .. .:: ..: ::::: : :.: ::.: .:::: : : XP_011 FQQPNSHPFPHSPNSSYPNSPGSSSSTYPHSPTS-SDPGSPFQMPADTPPPAYLPPEDPM 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB4 TQSG-QPVDATADRHVVLS-IPNGDFRPVCYEEPQHWCSVAYYELNNRVGETFQASSRSV ::.: ::.:.. . : : :: . : ::::.::::..::::::::::.:.::: :: XP_011 TQDGSQPMDTNMMAPPLPSEINRGDVQAVAYEEPKHWCSIVYYELNNRVGEAFHASSTSV 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB4 LIDGFTDPSNNRNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECVSDSSIF :.:::::::::.:::::::::::::::::::::::::::::::::::::::::.:::::: XP_011 LVDGFTDPSNNKNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIF 300 310 320 330 340 350 360 370 380 390 400 410 pF1KB4 VQSRNCNYQHGFHPATVCKIPSGCSLKVFNNQLFAQLLAQSVHHGFEVVYELTKMCTIRM ::::::::.:::::.::::::::::::.:::: :::::::::.::::.:::::::::::: XP_011 VQSRNCNYHHGFHPTTVCKIPSGCSLKIFNNQEFAQLLAQSVNHGFETVYELTKMCTIRM 360 370 380 390 400 410 420 430 440 450 460 pF1KB4 SFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS ::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS 420 430 440 450 460 >>XP_005263049 (OMIM: 601595) PREDICTED: mothers against (465 aa) initn: 2637 init1: 1354 opt: 2642 Z-score: 1681.8 bits: 320.5 E(85289): 6.1e-87 Smith-Waterman score: 2642; 81.5% identity (90.8% similar) in 465 aa overlap (7-467:3-465) 10 20 30 40 50 60 pF1KB4 MHSTTPISSLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDSLVKKLKKKKGAMDELERALS ..:::::::::::::::::::::::::::::::.::::::::::::.:::.::: XP_005 MNVTSLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDALVKKLKKKKGAMEELEKALS 10 20 30 40 50 70 80 90 100 110 120 pF1KB4 CPGQPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSK ::::::.::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 CPGQPSNCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSK 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB4 QKEVCINPYHYRRVETPVLPPVLVPRHSEYNPQLSLLAKFRSASLHSEPLMPHNATYPDS :::::::::::.:::.::::::::::::::::: ::::.::. . ..:: :: :::.::: XP_005 QKEVCINPYHYKRVESPVLPPVLVPRHSEYNPQHSLLAQFRNLG-QNEPHMPLNATFPDS 120 130 140 150 160 170 190 200 210 220 230 pF1KB4 FQQPPCSALPPSPSHAFSQSPCTAS--YPHSPGSPSEPESPYQHSVDTPPLPYHATEASE :::: .: ::. .. .:: ..: ::::: : :.: ::.: .:::: : : XP_005 FQQPNSHPFPHSPNSSYPNSPGSSSSTYPHSPTS-SDPGSPFQMPADTPPPAYLPPEDPM 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB4 TQSG-QPVDATADRHVVLS-IPNGDFRPVCYEEPQHWCSVAYYELNNRVGETFQASSRSV ::.: ::.:.. . : : :: . : ::::.::::..::::::::::.:.::: :: XP_005 TQDGSQPMDTNMMAPPLPSEINRGDVQAVAYEEPKHWCSIVYYELNNRVGEAFHASSTSV 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB4 LIDGFTDPSNNRNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECVSDSSIF :.:::::::::.:::::::::::::::::::::::::::::::::::::::::.:::::: XP_005 LVDGFTDPSNNKNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIF 300 310 320 330 340 350 360 370 380 390 400 410 pF1KB4 VQSRNCNYQHGFHPATVCKIPSGCSLKVFNNQLFAQLLAQSVHHGFEVVYELTKMCTIRM ::::::::.:::::.::::::::::::.:::: :::::::::.::::.:::::::::::: XP_005 VQSRNCNYHHGFHPTTVCKIPSGCSLKIFNNQEFAQLLAQSVNHGFETVYELTKMCTIRM 360 370 380 390 400 410 420 430 440 450 460 pF1KB4 SFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS ::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS 420 430 440 450 460 >>XP_011530264 (OMIM: 601595) PREDICTED: mothers against (465 aa) initn: 2637 init1: 1354 opt: 2642 Z-score: 1681.8 bits: 320.5 E(85289): 6.1e-87 Smith-Waterman score: 2642; 81.5% identity (90.8% similar) in 465 aa overlap (7-467:3-465) 10 20 30 40 50 60 pF1KB4 MHSTTPISSLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDSLVKKLKKKKGAMDELERALS ..:::::::::::::::::::::::::::::::.::::::::::::.:::.::: XP_011 MNVTSLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDALVKKLKKKKGAMEELEKALS 10 20 30 40 50 70 80 90 100 110 120 pF1KB4 CPGQPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSK ::::::.::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CPGQPSNCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSK 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB4 QKEVCINPYHYRRVETPVLPPVLVPRHSEYNPQLSLLAKFRSASLHSEPLMPHNATYPDS :::::::::::.:::.::::::::::::::::: ::::.::. . ..:: :: :::.::: XP_011 QKEVCINPYHYKRVESPVLPPVLVPRHSEYNPQHSLLAQFRNLG-QNEPHMPLNATFPDS 120 130 140 150 160 170 190 200 210 220 230 pF1KB4 FQQPPCSALPPSPSHAFSQSPCTAS--YPHSPGSPSEPESPYQHSVDTPPLPYHATEASE :::: .: ::. .. .:: ..: ::::: : :.: ::.: .:::: : : XP_011 FQQPNSHPFPHSPNSSYPNSPGSSSSTYPHSPTS-SDPGSPFQMPADTPPPAYLPPEDPM 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB4 TQSG-QPVDATADRHVVLS-IPNGDFRPVCYEEPQHWCSVAYYELNNRVGETFQASSRSV ::.: ::.:.. . : : :: . : ::::.::::..::::::::::.:.::: :: XP_011 TQDGSQPMDTNMMAPPLPSEINRGDVQAVAYEEPKHWCSIVYYELNNRVGEAFHASSTSV 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB4 LIDGFTDPSNNRNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECVSDSSIF :.:::::::::.:::::::::::::::::::::::::::::::::::::::::.:::::: XP_011 LVDGFTDPSNNKNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIF 300 310 320 330 340 350 360 370 380 390 400 410 pF1KB4 VQSRNCNYQHGFHPATVCKIPSGCSLKVFNNQLFAQLLAQSVHHGFEVVYELTKMCTIRM ::::::::.:::::.::::::::::::.:::: :::::::::.::::.:::::::::::: XP_011 VQSRNCNYHHGFHPTTVCKIPSGCSLKIFNNQEFAQLLAQSVNHGFETVYELTKMCTIRM 360 370 380 390 400 410 420 430 440 450 460 pF1KB4 SFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS ::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS 420 430 440 450 460 >>NP_001003688 (OMIM: 601595) mothers against decapentap (465 aa) initn: 2637 init1: 1354 opt: 2642 Z-score: 1681.8 bits: 320.5 E(85289): 6.1e-87 Smith-Waterman score: 2642; 81.5% identity (90.8% similar) in 465 aa overlap (7-467:3-465) 10 20 30 40 50 60 pF1KB4 MHSTTPISSLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDSLVKKLKKKKGAMDELERALS ..:::::::::::::::::::::::::::::::.::::::::::::.:::.::: NP_001 MNVTSLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDALVKKLKKKKGAMEELEKALS 10 20 30 40 50 70 80 90 100 110 120 pF1KB4 CPGQPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSK ::::::.::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CPGQPSNCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSK 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB4 QKEVCINPYHYRRVETPVLPPVLVPRHSEYNPQLSLLAKFRSASLHSEPLMPHNATYPDS :::::::::::.:::.::::::::::::::::: ::::.::. . ..:: :: :::.::: NP_001 QKEVCINPYHYKRVESPVLPPVLVPRHSEYNPQHSLLAQFRNLG-QNEPHMPLNATFPDS 120 130 140 150 160 170 190 200 210 220 230 pF1KB4 FQQPPCSALPPSPSHAFSQSPCTAS--YPHSPGSPSEPESPYQHSVDTPPLPYHATEASE :::: .: ::. .. .:: ..: ::::: : :.: ::.: .:::: : : NP_001 FQQPNSHPFPHSPNSSYPNSPGSSSSTYPHSPTS-SDPGSPFQMPADTPPPAYLPPEDPM 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB4 TQSG-QPVDATADRHVVLS-IPNGDFRPVCYEEPQHWCSVAYYELNNRVGETFQASSRSV ::.: ::.:.. . : : :: . : ::::.::::..::::::::::.:.::: :: NP_001 TQDGSQPMDTNMMAPPLPSEINRGDVQAVAYEEPKHWCSIVYYELNNRVGEAFHASSTSV 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB4 LIDGFTDPSNNRNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECVSDSSIF :.:::::::::.:::::::::::::::::::::::::::::::::::::::::.:::::: NP_001 LVDGFTDPSNNKNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIF 300 310 320 330 340 350 360 370 380 390 400 410 pF1KB4 VQSRNCNYQHGFHPATVCKIPSGCSLKVFNNQLFAQLLAQSVHHGFEVVYELTKMCTIRM ::::::::.:::::.::::::::::::.:::: :::::::::.::::.:::::::::::: NP_001 VQSRNCNYHHGFHPTTVCKIPSGCSLKIFNNQEFAQLLAQSVNHGFETVYELTKMCTIRM 360 370 380 390 400 410 420 430 440 450 460 pF1KB4 SFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS ::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS 420 430 440 450 460 >>NP_005891 (OMIM: 601595) mothers against decapentapleg (465 aa) initn: 2637 init1: 1354 opt: 2642 Z-score: 1681.8 bits: 320.5 E(85289): 6.1e-87 Smith-Waterman score: 2642; 81.5% identity (90.8% similar) in 465 aa overlap (7-467:3-465) 10 20 30 40 50 60 pF1KB4 MHSTTPISSLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDSLVKKLKKKKGAMDELERALS ..:::::::::::::::::::::::::::::::.::::::::::::.:::.::: NP_005 MNVTSLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDALVKKLKKKKGAMEELEKALS 10 20 30 40 50 70 80 90 100 110 120 pF1KB4 CPGQPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSK ::::::.::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 CPGQPSNCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSK 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB4 QKEVCINPYHYRRVETPVLPPVLVPRHSEYNPQLSLLAKFRSASLHSEPLMPHNATYPDS :::::::::::.:::.::::::::::::::::: ::::.::. . ..:: :: :::.::: NP_005 QKEVCINPYHYKRVESPVLPPVLVPRHSEYNPQHSLLAQFRNLG-QNEPHMPLNATFPDS 120 130 140 150 160 170 190 200 210 220 230 pF1KB4 FQQPPCSALPPSPSHAFSQSPCTAS--YPHSPGSPSEPESPYQHSVDTPPLPYHATEASE :::: .: ::. .. .:: ..: ::::: : :.: ::.: .:::: : : NP_005 FQQPNSHPFPHSPNSSYPNSPGSSSSTYPHSPTS-SDPGSPFQMPADTPPPAYLPPEDPM 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB4 TQSG-QPVDATADRHVVLS-IPNGDFRPVCYEEPQHWCSVAYYELNNRVGETFQASSRSV ::.: ::.:.. . : : :: . : ::::.::::..::::::::::.:.::: :: NP_005 TQDGSQPMDTNMMAPPLPSEINRGDVQAVAYEEPKHWCSIVYYELNNRVGEAFHASSTSV 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB4 LIDGFTDPSNNRNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECVSDSSIF :.:::::::::.:::::::::::::::::::::::::::::::::::::::::.:::::: NP_005 LVDGFTDPSNNKNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIF 300 310 320 330 340 350 360 370 380 390 400 410 pF1KB4 VQSRNCNYQHGFHPATVCKIPSGCSLKVFNNQLFAQLLAQSVHHGFEVVYELTKMCTIRM ::::::::.:::::.::::::::::::.:::: :::::::::.::::.:::::::::::: NP_005 VQSRNCNYHHGFHPTTVCKIPSGCSLKIFNNQEFAQLLAQSVNHGFETVYELTKMCTIRM 360 370 380 390 400 410 420 430 440 450 460 pF1KB4 SFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS ::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 SFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS 420 430 440 450 460 >>XP_006714280 (OMIM: 601595) PREDICTED: mothers against (465 aa) initn: 2637 init1: 1354 opt: 2642 Z-score: 1681.8 bits: 320.5 E(85289): 6.1e-87 Smith-Waterman score: 2642; 81.5% identity (90.8% similar) in 465 aa overlap (7-467:3-465) 10 20 30 40 50 60 pF1KB4 MHSTTPISSLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDSLVKKLKKKKGAMDELERALS ..:::::::::::::::::::::::::::::::.::::::::::::.:::.::: XP_006 MNVTSLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDALVKKLKKKKGAMEELEKALS 10 20 30 40 50 70 80 90 100 110 120 pF1KB4 CPGQPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSK ::::::.::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 CPGQPSNCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSK 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB4 QKEVCINPYHYRRVETPVLPPVLVPRHSEYNPQLSLLAKFRSASLHSEPLMPHNATYPDS :::::::::::.:::.::::::::::::::::: ::::.::. . ..:: :: :::.::: XP_006 QKEVCINPYHYKRVESPVLPPVLVPRHSEYNPQHSLLAQFRNLG-QNEPHMPLNATFPDS 120 130 140 150 160 170 190 200 210 220 230 pF1KB4 FQQPPCSALPPSPSHAFSQSPCTAS--YPHSPGSPSEPESPYQHSVDTPPLPYHATEASE :::: .: ::. .. .:: ..: ::::: : :.: ::.: .:::: : : XP_006 FQQPNSHPFPHSPNSSYPNSPGSSSSTYPHSPTS-SDPGSPFQMPADTPPPAYLPPEDPM 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB4 TQSG-QPVDATADRHVVLS-IPNGDFRPVCYEEPQHWCSVAYYELNNRVGETFQASSRSV ::.: ::.:.. . : : :: . : ::::.::::..::::::::::.:.::: :: XP_006 TQDGSQPMDTNMMAPPLPSEINRGDVQAVAYEEPKHWCSIVYYELNNRVGEAFHASSTSV 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB4 LIDGFTDPSNNRNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECVSDSSIF :.:::::::::.:::::::::::::::::::::::::::::::::::::::::.:::::: XP_006 LVDGFTDPSNNKNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIF 300 310 320 330 340 350 360 370 380 390 400 410 pF1KB4 VQSRNCNYQHGFHPATVCKIPSGCSLKVFNNQLFAQLLAQSVHHGFEVVYELTKMCTIRM ::::::::.:::::.::::::::::::.:::: :::::::::.::::.:::::::::::: XP_006 VQSRNCNYHHGFHPTTVCKIPSGCSLKIFNNQEFAQLLAQSVNHGFETVYELTKMCTIRM 360 370 380 390 400 410 420 430 440 450 460 pF1KB4 SFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS ::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS 420 430 440 450 460 >>XP_011530263 (OMIM: 601595) PREDICTED: mothers against (465 aa) initn: 2637 init1: 1354 opt: 2642 Z-score: 1681.8 bits: 320.5 E(85289): 6.1e-87 Smith-Waterman score: 2642; 81.5% identity (90.8% similar) in 465 aa overlap (7-467:3-465) 10 20 30 40 50 60 pF1KB4 MHSTTPISSLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDSLVKKLKKKKGAMDELERALS ..:::::::::::::::::::::::::::::::.::::::::::::.:::.::: XP_011 MNVTSLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDALVKKLKKKKGAMEELEKALS 10 20 30 40 50 70 80 90 100 110 120 pF1KB4 CPGQPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSK ::::::.::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CPGQPSNCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSK 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB4 QKEVCINPYHYRRVETPVLPPVLVPRHSEYNPQLSLLAKFRSASLHSEPLMPHNATYPDS :::::::::::.:::.::::::::::::::::: ::::.::. . ..:: :: :::.::: XP_011 QKEVCINPYHYKRVESPVLPPVLVPRHSEYNPQHSLLAQFRNLG-QNEPHMPLNATFPDS 120 130 140 150 160 170 190 200 210 220 230 pF1KB4 FQQPPCSALPPSPSHAFSQSPCTAS--YPHSPGSPSEPESPYQHSVDTPPLPYHATEASE :::: .: ::. .. .:: ..: ::::: : :.: ::.: .:::: : : XP_011 FQQPNSHPFPHSPNSSYPNSPGSSSSTYPHSPTS-SDPGSPFQMPADTPPPAYLPPEDPM 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB4 TQSG-QPVDATADRHVVLS-IPNGDFRPVCYEEPQHWCSVAYYELNNRVGETFQASSRSV ::.: ::.:.. . : : :: . : ::::.::::..::::::::::.:.::: :: XP_011 TQDGSQPMDTNMMAPPLPSEINRGDVQAVAYEEPKHWCSIVYYELNNRVGEAFHASSTSV 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB4 LIDGFTDPSNNRNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECVSDSSIF :.:::::::::.:::::::::::::::::::::::::::::::::::::::::.:::::: XP_011 LVDGFTDPSNNKNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIF 300 310 320 330 340 350 360 370 380 390 400 410 pF1KB4 VQSRNCNYQHGFHPATVCKIPSGCSLKVFNNQLFAQLLAQSVHHGFEVVYELTKMCTIRM ::::::::.:::::.::::::::::::.:::: :::::::::.::::.:::::::::::: XP_011 VQSRNCNYHHGFHPTTVCKIPSGCSLKIFNNQEFAQLLAQSVNHGFETVYELTKMCTIRM 360 370 380 390 400 410 420 430 440 450 460 pF1KB4 SFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS ::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS 420 430 440 450 460 >>XP_011530265 (OMIM: 601595) PREDICTED: mothers against (465 aa) initn: 2637 init1: 1354 opt: 2642 Z-score: 1681.8 bits: 320.5 E(85289): 6.1e-87 Smith-Waterman score: 2642; 81.5% identity (90.8% similar) in 465 aa overlap (7-467:3-465) 10 20 30 40 50 60 pF1KB4 MHSTTPISSLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDSLVKKLKKKKGAMDELERALS ..:::::::::::::::::::::::::::::::.::::::::::::.:::.::: XP_011 MNVTSLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDALVKKLKKKKGAMEELEKALS 10 20 30 40 50 70 80 90 100 110 120 pF1KB4 CPGQPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSK ::::::.::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CPGQPSNCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSK 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB4 QKEVCINPYHYRRVETPVLPPVLVPRHSEYNPQLSLLAKFRSASLHSEPLMPHNATYPDS :::::::::::.:::.::::::::::::::::: ::::.::. . ..:: :: :::.::: XP_011 QKEVCINPYHYKRVESPVLPPVLVPRHSEYNPQHSLLAQFRNLG-QNEPHMPLNATFPDS 120 130 140 150 160 170 190 200 210 220 230 pF1KB4 FQQPPCSALPPSPSHAFSQSPCTAS--YPHSPGSPSEPESPYQHSVDTPPLPYHATEASE :::: .: ::. .. .:: ..: ::::: : :.: ::.: .:::: : : XP_011 FQQPNSHPFPHSPNSSYPNSPGSSSSTYPHSPTS-SDPGSPFQMPADTPPPAYLPPEDPM 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB4 TQSG-QPVDATADRHVVLS-IPNGDFRPVCYEEPQHWCSVAYYELNNRVGETFQASSRSV ::.: ::.:.. . : : :: . : ::::.::::..::::::::::.:.::: :: XP_011 TQDGSQPMDTNMMAPPLPSEINRGDVQAVAYEEPKHWCSIVYYELNNRVGEAFHASSTSV 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB4 LIDGFTDPSNNRNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECVSDSSIF :.:::::::::.:::::::::::::::::::::::::::::::::::::::::.:::::: XP_011 LVDGFTDPSNNKNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIF 300 310 320 330 340 350 360 370 380 390 400 410 pF1KB4 VQSRNCNYQHGFHPATVCKIPSGCSLKVFNNQLFAQLLAQSVHHGFEVVYELTKMCTIRM ::::::::.:::::.::::::::::::.:::: :::::::::.::::.:::::::::::: XP_011 VQSRNCNYHHGFHPTTVCKIPSGCSLKIFNNQEFAQLLAQSVNHGFETVYELTKMCTIRM 360 370 380 390 400 410 420 430 440 450 460 pF1KB4 SFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS ::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS 420 430 440 450 460 467 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 03:01:26 2016 done: Fri Nov 4 03:01:27 2016 Total Scan time: 10.010 Total Display time: 0.050 Function used was FASTA [36.3.4 Apr, 2011]