FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB4506, 655 aa 1>>>pF1KB4506 655 - 655 aa - 655 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 11.8445+/-0.000483; mu= -6.4702+/- 0.030 mean_var=578.5855+/-120.239, 0's: 0 Z-trim(123.7): 322 B-trim: 33 in 1/55 Lambda= 0.053320 statistics sampled from 43720 (44083) to 43720 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.774), E-opt: 0.2 (0.517), width: 16 Scan time: 10.770 The best scores are: opt bits E(85289) NP_001156757 (OMIM: 133450,612219) RNA-binding pro ( 655) 4722 378.3 4.8e-104 NP_005234 (OMIM: 133450,612219) RNA-binding protei ( 656) 4710 377.4 9e-104 XP_011528300 (OMIM: 133450,612219) PREDICTED: RNA- ( 656) 4710 377.4 9e-104 NP_053733 (OMIM: 133450,612219) RNA-binding protei ( 661) 4700 376.6 1.5e-103 XP_011528299 (OMIM: 133450,612219) PREDICTED: RNA- ( 657) 4698 376.5 1.7e-103 XP_016884136 (OMIM: 133450,612219) PREDICTED: RNA- ( 651) 4422 355.2 4.2e-97 XP_016884134 (OMIM: 133450,612219) PREDICTED: RNA- ( 652) 4410 354.3 8e-97 XP_016884135 (OMIM: 133450,612219) PREDICTED: RNA- ( 652) 4410 354.3 8e-97 XP_011528301 (OMIM: 133450,612219) PREDICTED: RNA- ( 653) 4398 353.4 1.5e-96 XP_016884150 (OMIM: 133450,612219) PREDICTED: RNA- ( 587) 4234 340.7 8.9e-93 XP_016884137 (OMIM: 133450,612219) PREDICTED: RNA- ( 638) 4062 327.5 9e-89 XP_011528302 (OMIM: 133450,612219) PREDICTED: RNA- ( 640) 4042 326.0 2.6e-88 XP_016884133 (OMIM: 133450,612219) PREDICTED: RNA- ( 668) 3937 317.9 7.2e-86 XP_011528298 (OMIM: 133450,612219) PREDICTED: RNA- ( 669) 3925 317.0 1.4e-85 XP_005261446 (OMIM: 133450,612219) PREDICTED: RNA- ( 669) 3920 316.6 1.8e-85 XP_011528297 (OMIM: 133450,612219) PREDICTED: RNA- ( 670) 3908 315.7 3.4e-85 XP_016884147 (OMIM: 133450,612219) PREDICTED: RNA- ( 600) 3597 291.7 5.1e-78 XP_016884148 (OMIM: 133450,612219) PREDICTED: RNA- ( 599) 3595 291.6 5.6e-78 NP_001156758 (OMIM: 133450,612219) RNA-binding pro ( 600) 3583 290.7 1.1e-77 XP_016884146 (OMIM: 133450,612219) PREDICTED: RNA- ( 601) 3432 279.0 3.4e-74 XP_016884138 (OMIM: 133450,612219) PREDICTED: RNA- ( 629) 3127 255.6 4e-67 XP_016884142 (OMIM: 133450,612219) PREDICTED: RNA- ( 614) 3119 255.0 6e-67 XP_016884141 (OMIM: 133450,612219) PREDICTED: RNA- ( 615) 3107 254.1 1.1e-66 XP_016884140 (OMIM: 133450,612219) PREDICTED: RNA- ( 615) 3107 254.1 1.1e-66 XP_016884145 (OMIM: 133450,612219) PREDICTED: RNA- ( 611) 3101 253.6 1.6e-66 XP_016884149 (OMIM: 133450,612219) PREDICTED: RNA- ( 597) 3099 253.4 1.7e-66 XP_016884139 (OMIM: 133450,612219) PREDICTED: RNA- ( 616) 3095 253.1 2.2e-66 XP_016884151 (OMIM: 133450,612219) PREDICTED: RNA- ( 582) 2935 240.8 1.1e-62 XP_016884143 (OMIM: 133450,612219) PREDICTED: RNA- ( 613) 2812 231.4 7.7e-60 XP_016884144 (OMIM: 133450,612219) PREDICTED: RNA- ( 612) 2810 231.2 8.6e-60 XP_011528303 (OMIM: 133450,612219) PREDICTED: RNA- ( 614) 2800 230.4 1.5e-59 XP_005261447 (OMIM: 133450,612219) PREDICTED: RNA- ( 613) 2798 230.3 1.6e-59 XP_016884155 (OMIM: 133450,612219) PREDICTED: RNA- ( 317) 2397 199.1 2.1e-50 XP_016884154 (OMIM: 133450,612219) PREDICTED: RNA- ( 317) 2397 199.1 2.1e-50 NP_001156759 (OMIM: 133450,612219) RNA-binding pro ( 354) 2226 186.0 2e-46 XP_016884152 (OMIM: 133450,612219) PREDICTED: RNA- ( 558) 1992 168.2 7.1e-41 XP_011528304 (OMIM: 133450,612219) PREDICTED: RNA- ( 597) 1771 151.3 9.7e-36 XP_016884153 (OMIM: 133450,612219) PREDICTED: RNA- ( 330) 1612 138.7 3.2e-32 NP_001164408 (OMIM: 137070,608030,614782) RNA-bind ( 522) 1072 97.4 1.4e-19 XP_011544083 (OMIM: 137070,608030,614782) PREDICTE ( 524) 1064 96.8 2.1e-19 NP_004951 (OMIM: 137070,608030,614782) RNA-binding ( 526) 1060 96.5 2.6e-19 NP_001164105 (OMIM: 137070,608030,614782) RNA-bind ( 525) 1059 96.4 2.7e-19 NP_003478 (OMIM: 601574,612237) TATA-binding prote ( 589) 998 91.8 7.6e-18 NP_631961 (OMIM: 601574,612237) TATA-binding prote ( 592) 989 91.1 1.2e-17 XP_011523617 (OMIM: 601574,612237) PREDICTED: TATA ( 501) 917 85.5 5.2e-16 XP_005255290 (OMIM: 137070,608030,614782) PREDICTE ( 321) 642 64.1 9.1e-10 XP_011544084 (OMIM: 137070,608030,614782) PREDICTE ( 321) 642 64.1 9.1e-10 XP_016880670 (OMIM: 601574,612237) PREDICTED: TATA ( 323) 521 54.8 5.8e-07 XP_016874320 (OMIM: 108300,120140,132450,150600,15 (1305) 434 48.8 0.00015 XP_016869755 (OMIM: 120215,130000) PREDICTED: coll (1715) 425 48.3 0.00028 >>NP_001156757 (OMIM: 133450,612219) RNA-binding protein (655 aa) initn: 4722 init1: 4722 opt: 4722 Z-score: 1989.0 bits: 378.3 E(85289): 4.8e-104 Smith-Waterman score: 4722; 100.0% identity (100.0% similar) in 655 aa overlap (1-655:1-655) 10 20 30 40 50 60 pF1KB4 MASTDYSTYSQAAAQQGYSAYTAQPTQGYAQTTQAYGQQSYGTYGQPTDVSYTQAQTTAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MASTDYSTYSQAAAQQGYSAYTAQPTQGYAQTTQAYGQQSYGTYGQPTDVSYTQAQTTAT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 YGQTAYATSYGQPPTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQSAYGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YGQTAYATSYGQPPTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQSAYGT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 QPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQVPGSYP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQVPGSYP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 MQPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MQPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 PPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDNR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 GRGRGGFDRGGMSRGGRGGGRGGMGAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GRGRGGFDRGGMSRGGRGGGRGGMGAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB4 AIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPP 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB4 TAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGPG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB4 GPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECN 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB4 QCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGFRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGFRG 550 560 570 580 590 600 610 620 630 640 650 pF1KB4 GRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGKMDKGEHRQERRDRPY ::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGKMDKGEHRQERRDRPY 610 620 630 640 650 >>NP_005234 (OMIM: 133450,612219) RNA-binding protein EW (656 aa) initn: 2626 init1: 2508 opt: 4710 Z-score: 1984.0 bits: 377.4 E(85289): 9e-104 Smith-Waterman score: 4710; 99.8% identity (99.8% similar) in 656 aa overlap (1-655:1-656) 10 20 30 40 50 60 pF1KB4 MASTDYSTYSQAAAQQGYSAYTAQPTQGYAQTTQAYGQQSYGTYGQPTDVSYTQAQTTAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 MASTDYSTYSQAAAQQGYSAYTAQPTQGYAQTTQAYGQQSYGTYGQPTDVSYTQAQTTAT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 YGQTAYATSYGQPPTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQSAYGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 YGQTAYATSYGQPPTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQSAYGT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 QPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQVPGSYP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 QPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQVPGSYP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 MQPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 MQPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 PPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 PPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDNR 250 260 270 280 290 300 310 320 330 340 350 pF1KB4 GRGRGGFDRGGMSRGGRGGGRGGMG-AGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDN ::::::::::::::::::::::::: :::::::::::::::::::::::::::::::::: NP_005 GRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDN 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB4 SAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 SAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDP 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB4 PTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 PTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGP 430 440 450 460 470 480 480 490 500 510 520 530 pF1KB4 GGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTEC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 GGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTEC 490 500 510 520 530 540 540 550 560 570 580 590 pF1KB4 NQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 NQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGFR 550 560 570 580 590 600 600 610 620 630 640 650 pF1KB4 GGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGKMDKGEHRQERRDRPY :::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 GGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGKMDKGEHRQERRDRPY 610 620 630 640 650 >>XP_011528300 (OMIM: 133450,612219) PREDICTED: RNA-bind (656 aa) initn: 4518 init1: 4518 opt: 4710 Z-score: 1984.0 bits: 377.4 E(85289): 9e-104 Smith-Waterman score: 4710; 99.8% identity (99.8% similar) in 656 aa overlap (1-655:1-656) 10 20 30 40 50 pF1KB4 MASTDYSTYSQAAAQQGYSAYTAQPTQGYAQTTQ-AYGQQSYGTYGQPTDVSYTQAQTTA :::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::: XP_011 MASTDYSTYSQAAAQQGYSAYTAQPTQGYAQTTQQAYGQQSYGTYGQPTDVSYTQAQTTA 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB4 TYGQTAYATSYGQPPTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQSAYG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TYGQTAYATSYGQPPTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQSAYG 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB4 TQPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQVPGSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TQPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQVPGSY 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB4 PMQPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PMQPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTS 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB4 YPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDN 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB4 RGRGRGGFDRGGMSRGGRGGGRGGMGAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RGRGRGGFDRGGMSRGGRGGGRGGMGAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDN 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB4 SAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDP 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB4 PTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGP 430 440 450 460 470 480 480 490 500 510 520 530 pF1KB4 GGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTEC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTEC 490 500 510 520 530 540 540 550 560 570 580 590 pF1KB4 NQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGFR 550 560 570 580 590 600 600 610 620 630 640 650 pF1KB4 GGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGKMDKGEHRQERRDRPY :::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGKMDKGEHRQERRDRPY 610 620 630 640 650 >>NP_053733 (OMIM: 133450,612219) RNA-binding protein EW (661 aa) initn: 4239 init1: 4239 opt: 4700 Z-score: 1979.8 bits: 376.6 E(85289): 1.5e-103 Smith-Waterman score: 4700; 99.1% identity (99.1% similar) in 661 aa overlap (1-655:1-661) 10 20 30 40 50 60 pF1KB4 MASTDYSTYSQAAAQQGYSAYTAQPTQGYAQTTQAYGQQSYGTYGQPTDVSYTQAQTTAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_053 MASTDYSTYSQAAAQQGYSAYTAQPTQGYAQTTQAYGQQSYGTYGQPTDVSYTQAQTTAT 10 20 30 40 50 60 70 80 90 100 110 pF1KB4 YGQTAYATSYGQPPT------GYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAA ::::::::::::::: ::::::::::::::::::::::::::::::::::::::: NP_053 YGQTAYATSYGQPPTVEGTSTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAA 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB4 QSAYGTQPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_053 QSAYGTQPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQ 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB4 VPGSYPMQPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_053 VPGSYPMQPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQ 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB4 QPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_053 QPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSM 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB4 SGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGAGERGGFNKPGGPMDEGPDLDLGPPVDPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_053 SGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGAGERGGFNKPGGPMDEGPDLDLGPPVDPD 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB4 EDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_053 EDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATV 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB4 SYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_053 SYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPG 430 440 450 460 470 480 480 490 500 510 520 530 pF1KB4 GPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_053 GPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFA 490 500 510 520 530 540 540 550 560 570 580 590 pF1KB4 WRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_053 WRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGD 550 560 570 580 590 600 600 610 620 630 640 650 pF1KB4 RGGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGKMDKGEHRQERRDRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_053 RGGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGKMDKGEHRQERRDRP 610 620 630 640 650 660 pF1KB4 Y : NP_053 Y >>XP_011528299 (OMIM: 133450,612219) PREDICTED: RNA-bind (657 aa) initn: 2709 init1: 2508 opt: 4698 Z-score: 1979.0 bits: 376.5 E(85289): 1.7e-103 Smith-Waterman score: 4698; 99.7% identity (99.7% similar) in 657 aa overlap (1-655:1-657) 10 20 30 40 50 pF1KB4 MASTDYSTYSQAAAQQGYSAYTAQPTQGYAQTTQ-AYGQQSYGTYGQPTDVSYTQAQTTA :::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::: XP_011 MASTDYSTYSQAAAQQGYSAYTAQPTQGYAQTTQQAYGQQSYGTYGQPTDVSYTQAQTTA 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB4 TYGQTAYATSYGQPPTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQSAYG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TYGQTAYATSYGQPPTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQSAYG 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB4 TQPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQVPGSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TQPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQVPGSY 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB4 PMQPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PMQPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTS 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB4 YPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDN 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB4 RGRGRGGFDRGGMSRGGRGGGRGGMG-AGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSD :::::::::::::::::::::::::: ::::::::::::::::::::::::::::::::: XP_011 RGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSD 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB4 NSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYED 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB4 PPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGG 430 440 450 460 470 480 480 490 500 510 520 530 pF1KB4 PGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTE 490 500 510 520 530 540 540 550 560 570 580 590 pF1KB4 CNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGF 550 560 570 580 590 600 600 610 620 630 640 650 pF1KB4 RGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGKMDKGEHRQERRDRPY ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGKMDKGEHRQERRDRPY 610 620 630 640 650 >>XP_016884136 (OMIM: 133450,612219) PREDICTED: RNA-bind (651 aa) initn: 3993 init1: 3739 opt: 4422 Z-score: 1864.3 bits: 355.2 E(85289): 4.2e-97 Smith-Waterman score: 4502; 95.5% identity (95.5% similar) in 668 aa overlap (1-655:1-651) 10 20 30 40 50 60 pF1KB4 MASTDYSTYSQAAAQQGYSAYTAQPTQGYAQTTQAYGQQSYGTYGQPTDVSYTQAQTTAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MASTDYSTYSQAAAQQGYSAYTAQPTQGYAQTTQAYGQQSYGTYGQPTDVSYTQAQTTAT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 YGQTAYATSYGQPPTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQSAYGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YGQTAYATSYGQPPTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQSAYGT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 QPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQVPGSYP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQVPGSYP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 MQPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MQPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 PPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDNR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 GRGRGGFDRGGMSRGGRGGGRGGMGAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GRGRGGFDRGGMSRGGRGGGRGGMGAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB4 AIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPP 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB4 TAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGPG 430 440 450 460 470 480 490 500 510 520 pF1KB4 GPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNP-------------G :::::::::::::::::::::::::::::::::::::::::::::: : XP_016 GPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPSIGDFCCDVIVCRG 490 500 510 520 530 540 530 540 550 560 570 580 pF1KB4 CGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMF ::::::::::::::: :::::::::::::::::::::::::::: XP_016 CGNQNFAWRTECNQC-----------------GDRGRGGPGGMRGGRGGLMDRGGPGGMF 550 560 570 580 590 600 610 620 630 640 pF1KB4 RGGRGGDRGGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGKMDKGEHR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RGGRGGDRGGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGKMDKGEHR 590 600 610 620 630 640 650 pF1KB4 QERRDRPY :::::::: XP_016 QERRDRPY 650 >>XP_016884134 (OMIM: 133450,612219) PREDICTED: RNA-bind (652 aa) initn: 3895 init1: 2229 opt: 4410 Z-score: 1859.3 bits: 354.3 E(85289): 8e-97 Smith-Waterman score: 4490; 95.4% identity (95.4% similar) in 669 aa overlap (1-655:1-652) 10 20 30 40 50 60 pF1KB4 MASTDYSTYSQAAAQQGYSAYTAQPTQGYAQTTQAYGQQSYGTYGQPTDVSYTQAQTTAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MASTDYSTYSQAAAQQGYSAYTAQPTQGYAQTTQAYGQQSYGTYGQPTDVSYTQAQTTAT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 YGQTAYATSYGQPPTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQSAYGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YGQTAYATSYGQPPTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQSAYGT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 QPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQVPGSYP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQVPGSYP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 MQPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MQPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 PPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDNR 250 260 270 280 290 300 310 320 330 340 350 pF1KB4 GRGRGGFDRGGMSRGGRGGGRGGMG-AGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDN ::::::::::::::::::::::::: :::::::::::::::::::::::::::::::::: XP_016 GRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDN 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB4 SAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDP 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB4 PTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGP 430 440 450 460 470 480 480 490 500 510 520 pF1KB4 GGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNP------------- ::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPSIGDFCCDVIVCR 490 500 510 520 530 540 530 540 550 560 570 580 pF1KB4 GCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGM :::::::::::::::: ::::::::::::::::::::::::::: XP_016 GCGNQNFAWRTECNQC-----------------GDRGRGGPGGMRGGRGGLMDRGGPGGM 550 560 570 580 590 600 610 620 630 640 pF1KB4 FRGGRGGDRGGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGKMDKGEH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FRGGRGGDRGGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGKMDKGEH 590 600 610 620 630 640 650 pF1KB4 RQERRDRPY ::::::::: XP_016 RQERRDRPY 650 >>XP_016884135 (OMIM: 133450,612219) PREDICTED: RNA-bind (652 aa) initn: 3891 init1: 3535 opt: 4410 Z-score: 1859.3 bits: 354.3 E(85289): 8e-97 Smith-Waterman score: 4490; 95.4% identity (95.4% similar) in 669 aa overlap (1-655:1-652) 10 20 30 40 50 pF1KB4 MASTDYSTYSQAAAQQGYSAYTAQPTQGYAQTTQ-AYGQQSYGTYGQPTDVSYTQAQTTA :::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::: XP_016 MASTDYSTYSQAAAQQGYSAYTAQPTQGYAQTTQQAYGQQSYGTYGQPTDVSYTQAQTTA 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB4 TYGQTAYATSYGQPPTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQSAYG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TYGQTAYATSYGQPPTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQSAYG 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB4 TQPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQVPGSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TQPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQVPGSY 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB4 PMQPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PMQPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTS 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB4 YPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDN 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB4 RGRGRGGFDRGGMSRGGRGGGRGGMGAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RGRGRGGFDRGGMSRGGRGGGRGGMGAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDN 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB4 SAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDP 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB4 PTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGP 430 440 450 460 470 480 480 490 500 510 520 pF1KB4 GGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNP------------- ::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPSIGDFCCDVIVCR 490 500 510 520 530 540 530 540 550 560 570 580 pF1KB4 GCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGM :::::::::::::::: ::::::::::::::::::::::::::: XP_016 GCGNQNFAWRTECNQC-----------------GDRGRGGPGGMRGGRGGLMDRGGPGGM 550 560 570 580 590 600 610 620 630 640 pF1KB4 FRGGRGGDRGGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGKMDKGEH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FRGGRGGDRGGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGKMDKGEH 590 600 610 620 630 640 650 pF1KB4 RQERRDRPY ::::::::: XP_016 RQERRDRPY 650 >>XP_011528301 (OMIM: 133450,612219) PREDICTED: RNA-bind (653 aa) initn: 3691 init1: 2025 opt: 4398 Z-score: 1854.3 bits: 353.4 E(85289): 1.5e-96 Smith-Waterman score: 4478; 95.2% identity (95.2% similar) in 670 aa overlap (1-655:1-653) 10 20 30 40 50 pF1KB4 MASTDYSTYSQAAAQQGYSAYTAQPTQGYAQTTQ-AYGQQSYGTYGQPTDVSYTQAQTTA :::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::: XP_011 MASTDYSTYSQAAAQQGYSAYTAQPTQGYAQTTQQAYGQQSYGTYGQPTDVSYTQAQTTA 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB4 TYGQTAYATSYGQPPTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQSAYG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TYGQTAYATSYGQPPTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQSAYG 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB4 TQPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQVPGSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TQPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQVPGSY 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB4 PMQPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PMQPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTS 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB4 YPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDN 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB4 RGRGRGGFDRGGMSRGGRGGGRGGMG-AGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSD :::::::::::::::::::::::::: ::::::::::::::::::::::::::::::::: XP_011 RGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSD 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB4 NSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYED 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB4 PPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGG 430 440 450 460 470 480 480 490 500 510 520 pF1KB4 PGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNP------------ :::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPSIGDFCCDVIVC 490 500 510 520 530 540 530 540 550 560 570 580 pF1KB4 -GCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGG :::::::::::::::: :::::::::::::::::::::::::: XP_011 RGCGNQNFAWRTECNQC-----------------GDRGRGGPGGMRGGRGGLMDRGGPGG 550 560 570 580 590 600 610 620 630 640 pF1KB4 MFRGGRGGDRGGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGKMDKGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MFRGGRGGDRGGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGKMDKGE 590 600 610 620 630 640 650 pF1KB4 HRQERRDRPY :::::::::: XP_011 HRQERRDRPY 650 >>XP_016884150 (OMIM: 133450,612219) PREDICTED: RNA-bind (587 aa) initn: 4234 init1: 4234 opt: 4234 Z-score: 1786.7 bits: 340.7 E(85289): 8.9e-93 Smith-Waterman score: 4234; 100.0% identity (100.0% similar) in 580 aa overlap (76-655:8-587) 50 60 70 80 90 100 pF1KB4 QPTDVSYTQAQTTATYGQTAYATSYGQPPTGYTTPTAPQAYSQPVQGYGTGAYDTTTATV :::::::::::::::::::::::::::::: XP_016 MQLSFVLGYTTPTAPQAYSQPVQGYGTGAYDTTTATV 10 20 30 110 120 130 140 150 160 pF1KB4 TTTQASYAAQSAYGTQPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TTTQASYAAQSAYGTQPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGY 40 50 60 70 80 90 170 180 190 200 210 220 pF1KB4 GQSNYSYPQVPGSYPMQPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GQSNYSYPQVPGSYPMQPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSS 100 110 120 130 140 150 230 240 250 260 270 280 pF1KB4 YGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGF 160 170 180 190 200 210 290 300 310 320 330 340 pF1KB4 SGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGAGERGGFNKPGGPMDEGPDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGAGERGGFNKPGGPMDEGPDL 220 230 240 250 260 270 350 360 370 380 390 400 pF1KB4 DLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKET 280 290 300 310 320 330 410 420 430 440 450 460 pF1KB4 GKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGM 340 350 360 370 380 390 470 480 490 500 510 520 pF1KB4 PPPLRGGPGGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PPPLRGGPGGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPN 400 410 420 430 440 450 530 540 550 560 570 580 pF1KB4 PGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGG 460 470 480 490 500 510 590 600 610 620 630 640 pF1KB4 MFRGGRGGDRGGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGKMDKGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MFRGGRGGDRGGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGKMDKGE 520 530 540 550 560 570 650 pF1KB4 HRQERRDRPY :::::::::: XP_016 HRQERRDRPY 580 655 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 03:02:08 2016 done: Fri Nov 4 03:02:09 2016 Total Scan time: 10.770 Total Display time: 0.200 Function used was FASTA [36.3.4 Apr, 2011]