FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB4508, 389 aa 1>>>pF1KB4508 389 - 389 aa - 389 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.5019+/-0.00102; mu= 16.0868+/- 0.061 mean_var=71.1353+/-14.745, 0's: 0 Z-trim(104.4): 21 B-trim: 0 in 0/49 Lambda= 0.152066 statistics sampled from 7879 (7889) to 7879 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.598), E-opt: 0.2 (0.242), width: 16 Scan time: 2.810 The best scores are: opt bits E(32554) CCDS11925.1 SLC14A1 gene_id:6563|Hs108|chr18 ( 389) 2629 586.1 1.8e-167 CCDS45860.1 SLC14A1 gene_id:6563|Hs108|chr18 ( 445) 2629 586.2 2e-167 CCDS82252.1 SLC14A1 gene_id:6563|Hs108|chr18 ( 284) 1912 428.7 3.1e-120 CCDS77181.1 SLC14A1 gene_id:6563|Hs108|chr18 ( 257) 1751 393.4 1.2e-109 CCDS11924.1 SLC14A2 gene_id:8170|Hs108|chr18 ( 920) 1729 388.9 1e-107 >>CCDS11925.1 SLC14A1 gene_id:6563|Hs108|chr18 (389 aa) initn: 2629 init1: 2629 opt: 2629 Z-score: 3120.2 bits: 586.1 E(32554): 1.8e-167 Smith-Waterman score: 2629; 99.7% identity (100.0% similar) in 389 aa overlap (1-389:1-389) 10 20 30 40 50 60 pF1KB4 MEDSPTMVRVDSPTMVRGENQVSPCQGRRCFPKALGYVTGDMKELANQLKDKPVVLQFID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 MEDSPTMVRVDSPTMVRGENQVSPCQGRRCFPKALGYVTGDMKELANQLKDKPVVLQFID 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 WILRGISQVVFVNNPVSGILILVGLLVQNPWWALTGWLGTVVSTLMALLLSQDRSLIASG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 WILRGISQVVFVNNPVSGILILVGLLVQNPWWALTGWLGTVVSTLMALLLSQDRSLIASG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 LYGYNATLVGVLMAVFSDKGDYFWWLLLPVCAMSMTCPIFSSALNSMLSKWDLPVFTLPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 LYGYNATLVGVLMAVFSDKGDYFWWLLLPVCAMSMTCPIFSSALNSMLSKWDLPVFTLPF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 NMALSMYLSATGHYNPFFPAKLVIPITTAPNISWSDLSALELLKSIPVGVGQIYGCDNPW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 NMALSMYLSATGHYNPFFPAKLVIPITTAPNISWSDLSALELLKSIPVGVGQIYGCDNPW 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 TGGIFLGAILLSSPLMCLHAAIGSLLGIAAGLSLSAPFENIYFGLWGFNSSLACIAMGGM :::::::::::::::::::::::::::::::::::::::.:::::::::::::::::::: CCDS11 TGGIFLGAILLSSPLMCLHAAIGSLLGIAAGLSLSAPFEDIYFGLWGFNSSLACIAMGGM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 FMALTWQTHLLALGCALFTAYLGVGMANFMAEVGLPACTWPFCLATLLFLIMTTKNSNIY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 FMALTWQTHLLALGCALFTAYLGVGMANFMAEVGLPACTWPFCLATLLFLIMTTKNSNIY 310 320 330 340 350 360 370 380 pF1KB4 KMPLSKVTYPEENRIFYLQAKKRMVESPL ::::::::::::::::::::::::::::: CCDS11 KMPLSKVTYPEENRIFYLQAKKRMVESPL 370 380 >>CCDS45860.1 SLC14A1 gene_id:6563|Hs108|chr18 (445 aa) initn: 2629 init1: 2629 opt: 2629 Z-score: 3119.3 bits: 586.2 E(32554): 2e-167 Smith-Waterman score: 2629; 99.7% identity (100.0% similar) in 389 aa overlap (1-389:57-445) 10 20 30 pF1KB4 MEDSPTMVRVDSPTMVRGENQVSPCQGRRC :::::::::::::::::::::::::::::: CCDS45 AGDAARRGIARLSLALADGSQEQEPEEEIAMEDSPTMVRVDSPTMVRGENQVSPCQGRRC 30 40 50 60 70 80 40 50 60 70 80 90 pF1KB4 FPKALGYVTGDMKELANQLKDKPVVLQFIDWILRGISQVVFVNNPVSGILILVGLLVQNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 FPKALGYVTGDMKELANQLKDKPVVLQFIDWILRGISQVVFVNNPVSGILILVGLLVQNP 90 100 110 120 130 140 100 110 120 130 140 150 pF1KB4 WWALTGWLGTVVSTLMALLLSQDRSLIASGLYGYNATLVGVLMAVFSDKGDYFWWLLLPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 WWALTGWLGTVVSTLMALLLSQDRSLIASGLYGYNATLVGVLMAVFSDKGDYFWWLLLPV 150 160 170 180 190 200 160 170 180 190 200 210 pF1KB4 CAMSMTCPIFSSALNSMLSKWDLPVFTLPFNMALSMYLSATGHYNPFFPAKLVIPITTAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 CAMSMTCPIFSSALNSMLSKWDLPVFTLPFNMALSMYLSATGHYNPFFPAKLVIPITTAP 210 220 230 240 250 260 220 230 240 250 260 270 pF1KB4 NISWSDLSALELLKSIPVGVGQIYGCDNPWTGGIFLGAILLSSPLMCLHAAIGSLLGIAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 NISWSDLSALELLKSIPVGVGQIYGCDNPWTGGIFLGAILLSSPLMCLHAAIGSLLGIAA 270 280 290 300 310 320 280 290 300 310 320 330 pF1KB4 GLSLSAPFENIYFGLWGFNSSLACIAMGGMFMALTWQTHLLALGCALFTAYLGVGMANFM :::::::::.:::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 GLSLSAPFEDIYFGLWGFNSSLACIAMGGMFMALTWQTHLLALGCALFTAYLGVGMANFM 330 340 350 360 370 380 340 350 360 370 380 pF1KB4 AEVGLPACTWPFCLATLLFLIMTTKNSNIYKMPLSKVTYPEENRIFYLQAKKRMVESPL ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 AEVGLPACTWPFCLATLLFLIMTTKNSNIYKMPLSKVTYPEENRIFYLQAKKRMVESPL 390 400 410 420 430 440 >>CCDS82252.1 SLC14A1 gene_id:6563|Hs108|chr18 (284 aa) initn: 1912 init1: 1912 opt: 1912 Z-score: 2272.1 bits: 428.7 E(32554): 3.1e-120 Smith-Waterman score: 1912; 99.6% identity (100.0% similar) in 284 aa overlap (106-389:1-284) 80 90 100 110 120 130 pF1KB4 VSGILILVGLLVQNPWWALTGWLGTVVSTLMALLLSQDRSLIASGLYGYNATLVGVLMAV :::::::::::::::::::::::::::::: CCDS82 MALLLSQDRSLIASGLYGYNATLVGVLMAV 10 20 30 140 150 160 170 180 190 pF1KB4 FSDKGDYFWWLLLPVCAMSMTCPIFSSALNSMLSKWDLPVFTLPFNMALSMYLSATGHYN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 FSDKGDYFWWLLLPVCAMSMTCPIFSSALNSMLSKWDLPVFTLPFNMALSMYLSATGHYN 40 50 60 70 80 90 200 210 220 230 240 250 pF1KB4 PFFPAKLVIPITTAPNISWSDLSALELLKSIPVGVGQIYGCDNPWTGGIFLGAILLSSPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 PFFPAKLVIPITTAPNISWSDLSALELLKSIPVGVGQIYGCDNPWTGGIFLGAILLSSPL 100 110 120 130 140 150 260 270 280 290 300 310 pF1KB4 MCLHAAIGSLLGIAAGLSLSAPFENIYFGLWGFNSSLACIAMGGMFMALTWQTHLLALGC ::::::::::::::::::::::::.::::::::::::::::::::::::::::::::::: CCDS82 MCLHAAIGSLLGIAAGLSLSAPFEDIYFGLWGFNSSLACIAMGGMFMALTWQTHLLALGC 160 170 180 190 200 210 320 330 340 350 360 370 pF1KB4 ALFTAYLGVGMANFMAEVGLPACTWPFCLATLLFLIMTTKNSNIYKMPLSKVTYPEENRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 ALFTAYLGVGMANFMAEVGLPACTWPFCLATLLFLIMTTKNSNIYKMPLSKVTYPEENRI 220 230 240 250 260 270 380 pF1KB4 FYLQAKKRMVESPL :::::::::::::: CCDS82 FYLQAKKRMVESPL 280 >>CCDS77181.1 SLC14A1 gene_id:6563|Hs108|chr18 (257 aa) initn: 1751 init1: 1751 opt: 1751 Z-score: 2081.9 bits: 393.4 E(32554): 1.2e-109 Smith-Waterman score: 1751; 99.6% identity (100.0% similar) in 257 aa overlap (133-389:1-257) 110 120 130 140 150 160 pF1KB4 STLMALLLSQDRSLIASGLYGYNATLVGVLMAVFSDKGDYFWWLLLPVCAMSMTCPIFSS :::::::::::::::::::::::::::::: CCDS77 MAVFSDKGDYFWWLLLPVCAMSMTCPIFSS 10 20 30 170 180 190 200 210 220 pF1KB4 ALNSMLSKWDLPVFTLPFNMALSMYLSATGHYNPFFPAKLVIPITTAPNISWSDLSALEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 ALNSMLSKWDLPVFTLPFNMALSMYLSATGHYNPFFPAKLVIPITTAPNISWSDLSALEL 40 50 60 70 80 90 230 240 250 260 270 280 pF1KB4 LKSIPVGVGQIYGCDNPWTGGIFLGAILLSSPLMCLHAAIGSLLGIAAGLSLSAPFENIY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::.:: CCDS77 LKSIPVGVGQIYGCDNPWTGGIFLGAILLSSPLMCLHAAIGSLLGIAAGLSLSAPFEDIY 100 110 120 130 140 150 290 300 310 320 330 340 pF1KB4 FGLWGFNSSLACIAMGGMFMALTWQTHLLALGCALFTAYLGVGMANFMAEVGLPACTWPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 FGLWGFNSSLACIAMGGMFMALTWQTHLLALGCALFTAYLGVGMANFMAEVGLPACTWPF 160 170 180 190 200 210 350 360 370 380 pF1KB4 CLATLLFLIMTTKNSNIYKMPLSKVTYPEENRIFYLQAKKRMVESPL ::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 CLATLLFLIMTTKNSNIYKMPLSKVTYPEENRIFYLQAKKRMVESPL 220 230 240 250 >>CCDS11924.1 SLC14A2 gene_id:8170|Hs108|chr18 (920 aa) initn: 3497 init1: 1721 opt: 1729 Z-score: 2047.5 bits: 388.9 E(32554): 1e-107 Smith-Waterman score: 1729; 62.3% identity (87.9% similar) in 387 aa overlap (1-383:524-906) 10 20 pF1KB4 MEDSPTM---VRVDSPTMVRGENQVSPCQG ::.: . . ... . .:. .: : CCDS11 GKGEHQERQNKDPFPYRYRKPTVELLDLDTMEESSEIKVETNISKTSWIRSSMAAS---G 500 510 520 530 540 550 30 40 50 60 70 80 pF1KB4 RRCFPKALGYVTGDMKELANQLKDKPVVLQFIDWILRGISQVVFVNNPVSGILILVGLLV .: :::.:.::.::: .. :::: :.::.::.::: :::.:::::.:::::..::.. CCDS11 KRV-SKALSYITGEMKECGEGLKDKSPVFQFFDWVLRGTSQVMFVNNPLSGILIILGLFI 560 570 580 590 600 90 100 110 120 130 140 pF1KB4 QNPWWALTGWLGTVVSTLMALLLSQDRSLIASGLYGYNATLVGVLMAVFSDKGDYFWWLL ::::::..: :::..::: ::.::::.: ::.:..:::..:::.:::::::::::.:::: CCDS11 QNPWWAISGCLGTIMSTLTALILSQDKSAIAAGFHGYNGVLVGLLMAVFSDKGDYYWWLL 610 620 630 640 650 660 150 160 170 180 190 200 pF1KB4 LPVCAMSMTCPIFSSALNSMLSKWDLPVFTLPFNMALSMYLSATGHYNPFFPAKLVIPIT ::: :::.:::.::::....:::::::::::::.....::.:::::: :::. :. : . CCDS11 LPVIIMSMSCPILSSALGTIFSKWDLPVFTLPFNITVTLYLAATGHYNLFFPTTLLQPAS 670 680 690 700 710 720 210 220 230 240 250 260 pF1KB4 TAPNISWSDLSALELLKSIPVGVGQIYGCDNPWTGGIFLGAILLSSPLMCLHAAIGSLLG . :::.::.... ::..::::.::.::::::::::::: :...::::.:::::::: .: CCDS11 AMPNITWSEVQVPLLLRAIPVGIGQVYGCDNPWTGGIFLIALFISSPLICLHAAIGSTMG 730 740 750 760 770 780 270 280 290 300 310 320 pF1KB4 IAAGLSLSAPFENIYFGLWGFNSSLACIAMGGMFMALTWQTHLLALGCALFTAYLGVGMA . :.:....::..::::: ::::.:::::.::::...::::::::..::::.::::...: CCDS11 MLAALTIATPFDSIYFGLCGFNSTLACIAIGGMFYVITWQTHLLAIACALFAAYLGAALA 790 800 810 820 830 840 330 340 350 360 370 380 pF1KB4 NFMAEVGLPACTWPFCLATLLFLIMTTKNSNIYKMPLSKVTYPEENRIFYL-QAKKRMVE :... ::: :::::::..: ::..::.: :::.::::::::: :::.:: : ..: CCDS11 NMLSVFGLPPCTWPFCLSALTFLLLTTNNPAIYKLPLSKVTYPEANRIYYLSQERNRRAS 850 860 870 880 890 900 pF1KB4 SPL CCDS11 IITKYQAYDVS 910 920 >-- initn: 1822 init1: 1681 opt: 1696 Z-score: 2008.3 bits: 381.6 E(32554): 1.5e-105 Smith-Waterman score: 1696; 65.0% identity (88.5% similar) in 357 aa overlap (27-381:85-441) 10 20 30 40 50 pF1KB4 MEDSPTMVRVDSPTMVRGENQVSPCQGRRC--FPKALGYVTGDMKELANQLKDKPV :.:: . ::.::.:::::: :::: . CCDS11 SNEDSHIVKIEKLNERSKRKDDGVAHRDSAGQRCICLSKAVGYLTGDMKEYRIWLKDKHL 60 70 80 90 100 110 60 70 80 90 100 110 pF1KB4 VLQFIDWILRGISQVVFVNNPVSGILILVGLLVQNPWWALTGWLGTVVSTLMALLLSQDR .::::::.::: .::.:.:::.::..:..:::.:::::..:: :::::::: :: :.::: CCDS11 ALQFIDWVLRGTAQVMFINNPLSGLIIFIGLLIQNPWWTITGGLGTVVSTLTALALGQDR 120 130 140 150 160 170 120 130 140 150 160 170 pF1KB4 SLIASGLYGYNATLVGVLMAVFSDKGDYFWWLLLPVCAMSMTCPIFSSALNSMLSKWDLP : :::::.:::. :::.::::::.: ::.::::.:: .:.::..::::::..:::::: CCDS11 SAIASGLHGYNGMLVGLLMAVFSEKLDYYWWLLFPVTFTAMSCPVLSSALNSIFSKWDLP 180 190 200 210 220 230 180 190 200 210 220 230 pF1KB4 VFTLPFNMALSMYLSATGHYNPFFPAKLVIPITTAPNISWSDLSALELLKSIPVGVGQIY :::::::.:...::.:::::: :::. :: :....:::.:... ::..:::::::.: CCDS11 VFTLPFNIAVTLYLAATGHYNLFFPTTLVEPVSSVPNITWTEMEMPLLLQAIPVGVGQVY 240 250 260 270 280 290 240 250 260 270 280 290 pF1KB4 GCDNPWTGGIFLGAILLSSPLMCLHAAIGSLLGIAAGLSLSAPFENIYFGLWGFNSSLAC :::::::::.:: :...::::.::::::::..:. :.::...:::.:: :::..: :.: CCDS11 GCDNPWTGGVFLVALFISSPLICLHAAIGSIVGLLAALSVATPFETIYTGLWSYNCVLSC 300 310 320 330 340 350 300 310 320 330 340 350 pF1KB4 IAMGGMFMALTWQTHLLALGCALFTAYLGVGMANFMAEVGLPACTWPFCLATLLFLIMTT ::.::::.::::::::::: :::: ::. ....:.:. ::.: :: :::::..::..:: CCDS11 IAIGGMFYALTWQTHLLALICALFCAYMEAAISNIMSVVGVPPGTWAFCLATIIFLLLTT 360 370 380 390 400 410 360 370 380 pF1KB4 KNSNIYKMPLSKVTYPEENRIFYLQAKKRMVESPL .: :...::::::::: :::.:: .: CCDS11 NNPAIFRLPLSKVTYPEANRIYYLTVKSGEEEKAPSGGGGEHPPTAGPKVEEGSEAVLSK 420 430 440 450 460 470 389 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 05:52:54 2016 done: Sat Nov 5 05:52:54 2016 Total Scan time: 2.810 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]