FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB4508, 389 aa 1>>>pF1KB4508 389 - 389 aa - 389 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.9469+/-0.000428; mu= 19.3442+/- 0.026 mean_var=70.5903+/-14.760, 0's: 0 Z-trim(110.9): 30 B-trim: 0 in 0/50 Lambda= 0.152652 statistics sampled from 19388 (19410) to 19388 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.579), E-opt: 0.2 (0.228), width: 16 Scan time: 8.380 The best scores are: opt bits E(85289) NP_001139508 (OMIM: 111000,613868) urea transporte ( 389) 2629 588.4 9.6e-168 NP_056949 (OMIM: 111000,613868) urea transporter 1 ( 389) 2629 588.4 9.6e-168 XP_006722589 (OMIM: 111000,613868) PREDICTED: urea ( 424) 2629 588.4 1e-167 XP_011524444 (OMIM: 111000,613868) PREDICTED: urea ( 424) 2629 588.4 1e-167 NP_001122060 (OMIM: 111000,613868) urea transporte ( 445) 2629 588.5 1.1e-167 NP_001139509 (OMIM: 111000,613868) urea transporte ( 445) 2629 588.5 1.1e-167 XP_005258386 (OMIM: 111000,613868) PREDICTED: urea ( 402) 2246 504.1 2.4e-142 XP_011524446 (OMIM: 111000,613868) PREDICTED: urea ( 374) 2139 480.5 2.9e-135 NP_001295207 (OMIM: 111000,613868) urea transporte ( 284) 1912 430.4 2.6e-120 XP_005258390 (OMIM: 111000,613868) PREDICTED: urea ( 257) 1751 394.9 1.1e-109 NP_001295208 (OMIM: 111000,613868) urea transporte ( 257) 1751 394.9 1.1e-109 XP_016881505 (OMIM: 601611) PREDICTED: urea transp ( 875) 1729 390.5 8.2e-108 XP_016881504 (OMIM: 601611) PREDICTED: urea transp ( 920) 1729 390.5 8.6e-108 NP_009094 (OMIM: 601611) urea transporter 2 [Homo ( 920) 1729 390.5 8.6e-108 NP_001229621 (OMIM: 601611) urea transporter 2 [Ho ( 920) 1729 390.5 8.6e-108 >>NP_001139508 (OMIM: 111000,613868) urea transporter 1 (389 aa) initn: 2629 init1: 2629 opt: 2629 Z-score: 3132.5 bits: 588.4 E(85289): 9.6e-168 Smith-Waterman score: 2629; 99.7% identity (100.0% similar) in 389 aa overlap (1-389:1-389) 10 20 30 40 50 60 pF1KB4 MEDSPTMVRVDSPTMVRGENQVSPCQGRRCFPKALGYVTGDMKELANQLKDKPVVLQFID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MEDSPTMVRVDSPTMVRGENQVSPCQGRRCFPKALGYVTGDMKELANQLKDKPVVLQFID 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 WILRGISQVVFVNNPVSGILILVGLLVQNPWWALTGWLGTVVSTLMALLLSQDRSLIASG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WILRGISQVVFVNNPVSGILILVGLLVQNPWWALTGWLGTVVSTLMALLLSQDRSLIASG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 LYGYNATLVGVLMAVFSDKGDYFWWLLLPVCAMSMTCPIFSSALNSMLSKWDLPVFTLPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LYGYNATLVGVLMAVFSDKGDYFWWLLLPVCAMSMTCPIFSSALNSMLSKWDLPVFTLPF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 NMALSMYLSATGHYNPFFPAKLVIPITTAPNISWSDLSALELLKSIPVGVGQIYGCDNPW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NMALSMYLSATGHYNPFFPAKLVIPITTAPNISWSDLSALELLKSIPVGVGQIYGCDNPW 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 TGGIFLGAILLSSPLMCLHAAIGSLLGIAAGLSLSAPFENIYFGLWGFNSSLACIAMGGM :::::::::::::::::::::::::::::::::::::::.:::::::::::::::::::: NP_001 TGGIFLGAILLSSPLMCLHAAIGSLLGIAAGLSLSAPFEDIYFGLWGFNSSLACIAMGGM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 FMALTWQTHLLALGCALFTAYLGVGMANFMAEVGLPACTWPFCLATLLFLIMTTKNSNIY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FMALTWQTHLLALGCALFTAYLGVGMANFMAEVGLPACTWPFCLATLLFLIMTTKNSNIY 310 320 330 340 350 360 370 380 pF1KB4 KMPLSKVTYPEENRIFYLQAKKRMVESPL ::::::::::::::::::::::::::::: NP_001 KMPLSKVTYPEENRIFYLQAKKRMVESPL 370 380 >>NP_056949 (OMIM: 111000,613868) urea transporter 1 iso (389 aa) initn: 2629 init1: 2629 opt: 2629 Z-score: 3132.5 bits: 588.4 E(85289): 9.6e-168 Smith-Waterman score: 2629; 99.7% identity (100.0% similar) in 389 aa overlap (1-389:1-389) 10 20 30 40 50 60 pF1KB4 MEDSPTMVRVDSPTMVRGENQVSPCQGRRCFPKALGYVTGDMKELANQLKDKPVVLQFID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 MEDSPTMVRVDSPTMVRGENQVSPCQGRRCFPKALGYVTGDMKELANQLKDKPVVLQFID 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 WILRGISQVVFVNNPVSGILILVGLLVQNPWWALTGWLGTVVSTLMALLLSQDRSLIASG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 WILRGISQVVFVNNPVSGILILVGLLVQNPWWALTGWLGTVVSTLMALLLSQDRSLIASG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 LYGYNATLVGVLMAVFSDKGDYFWWLLLPVCAMSMTCPIFSSALNSMLSKWDLPVFTLPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 LYGYNATLVGVLMAVFSDKGDYFWWLLLPVCAMSMTCPIFSSALNSMLSKWDLPVFTLPF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 NMALSMYLSATGHYNPFFPAKLVIPITTAPNISWSDLSALELLKSIPVGVGQIYGCDNPW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 NMALSMYLSATGHYNPFFPAKLVIPITTAPNISWSDLSALELLKSIPVGVGQIYGCDNPW 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 TGGIFLGAILLSSPLMCLHAAIGSLLGIAAGLSLSAPFENIYFGLWGFNSSLACIAMGGM :::::::::::::::::::::::::::::::::::::::.:::::::::::::::::::: NP_056 TGGIFLGAILLSSPLMCLHAAIGSLLGIAAGLSLSAPFEDIYFGLWGFNSSLACIAMGGM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 FMALTWQTHLLALGCALFTAYLGVGMANFMAEVGLPACTWPFCLATLLFLIMTTKNSNIY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 FMALTWQTHLLALGCALFTAYLGVGMANFMAEVGLPACTWPFCLATLLFLIMTTKNSNIY 310 320 330 340 350 360 370 380 pF1KB4 KMPLSKVTYPEENRIFYLQAKKRMVESPL ::::::::::::::::::::::::::::: NP_056 KMPLSKVTYPEENRIFYLQAKKRMVESPL 370 380 >>XP_006722589 (OMIM: 111000,613868) PREDICTED: urea tra (424 aa) initn: 2629 init1: 2629 opt: 2629 Z-score: 3132.0 bits: 588.4 E(85289): 1e-167 Smith-Waterman score: 2629; 99.7% identity (100.0% similar) in 389 aa overlap (1-389:36-424) 10 20 30 pF1KB4 MEDSPTMVRVDSPTMVRGENQVSPCQGRRC :::::::::::::::::::::::::::::: XP_006 DTAPYEIKDQNILMVALQTLMAKEPEEEIAMEDSPTMVRVDSPTMVRGENQVSPCQGRRC 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB4 FPKALGYVTGDMKELANQLKDKPVVLQFIDWILRGISQVVFVNNPVSGILILVGLLVQNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FPKALGYVTGDMKELANQLKDKPVVLQFIDWILRGISQVVFVNNPVSGILILVGLLVQNP 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB4 WWALTGWLGTVVSTLMALLLSQDRSLIASGLYGYNATLVGVLMAVFSDKGDYFWWLLLPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 WWALTGWLGTVVSTLMALLLSQDRSLIASGLYGYNATLVGVLMAVFSDKGDYFWWLLLPV 130 140 150 160 170 180 160 170 180 190 200 210 pF1KB4 CAMSMTCPIFSSALNSMLSKWDLPVFTLPFNMALSMYLSATGHYNPFFPAKLVIPITTAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 CAMSMTCPIFSSALNSMLSKWDLPVFTLPFNMALSMYLSATGHYNPFFPAKLVIPITTAP 190 200 210 220 230 240 220 230 240 250 260 270 pF1KB4 NISWSDLSALELLKSIPVGVGQIYGCDNPWTGGIFLGAILLSSPLMCLHAAIGSLLGIAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 NISWSDLSALELLKSIPVGVGQIYGCDNPWTGGIFLGAILLSSPLMCLHAAIGSLLGIAA 250 260 270 280 290 300 280 290 300 310 320 330 pF1KB4 GLSLSAPFENIYFGLWGFNSSLACIAMGGMFMALTWQTHLLALGCALFTAYLGVGMANFM :::::::::.:::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GLSLSAPFEDIYFGLWGFNSSLACIAMGGMFMALTWQTHLLALGCALFTAYLGVGMANFM 310 320 330 340 350 360 340 350 360 370 380 pF1KB4 AEVGLPACTWPFCLATLLFLIMTTKNSNIYKMPLSKVTYPEENRIFYLQAKKRMVESPL ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AEVGLPACTWPFCLATLLFLIMTTKNSNIYKMPLSKVTYPEENRIFYLQAKKRMVESPL 370 380 390 400 410 420 >>XP_011524444 (OMIM: 111000,613868) PREDICTED: urea tra (424 aa) initn: 2629 init1: 2629 opt: 2629 Z-score: 3132.0 bits: 588.4 E(85289): 1e-167 Smith-Waterman score: 2629; 99.7% identity (100.0% similar) in 389 aa overlap (1-389:36-424) 10 20 30 pF1KB4 MEDSPTMVRVDSPTMVRGENQVSPCQGRRC :::::::::::::::::::::::::::::: XP_011 DTAPYEIKDQNILMVALQTLMAKEPEEEIAMEDSPTMVRVDSPTMVRGENQVSPCQGRRC 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB4 FPKALGYVTGDMKELANQLKDKPVVLQFIDWILRGISQVVFVNNPVSGILILVGLLVQNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FPKALGYVTGDMKELANQLKDKPVVLQFIDWILRGISQVVFVNNPVSGILILVGLLVQNP 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB4 WWALTGWLGTVVSTLMALLLSQDRSLIASGLYGYNATLVGVLMAVFSDKGDYFWWLLLPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WWALTGWLGTVVSTLMALLLSQDRSLIASGLYGYNATLVGVLMAVFSDKGDYFWWLLLPV 130 140 150 160 170 180 160 170 180 190 200 210 pF1KB4 CAMSMTCPIFSSALNSMLSKWDLPVFTLPFNMALSMYLSATGHYNPFFPAKLVIPITTAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CAMSMTCPIFSSALNSMLSKWDLPVFTLPFNMALSMYLSATGHYNPFFPAKLVIPITTAP 190 200 210 220 230 240 220 230 240 250 260 270 pF1KB4 NISWSDLSALELLKSIPVGVGQIYGCDNPWTGGIFLGAILLSSPLMCLHAAIGSLLGIAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NISWSDLSALELLKSIPVGVGQIYGCDNPWTGGIFLGAILLSSPLMCLHAAIGSLLGIAA 250 260 270 280 290 300 280 290 300 310 320 330 pF1KB4 GLSLSAPFENIYFGLWGFNSSLACIAMGGMFMALTWQTHLLALGCALFTAYLGVGMANFM :::::::::.:::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GLSLSAPFEDIYFGLWGFNSSLACIAMGGMFMALTWQTHLLALGCALFTAYLGVGMANFM 310 320 330 340 350 360 340 350 360 370 380 pF1KB4 AEVGLPACTWPFCLATLLFLIMTTKNSNIYKMPLSKVTYPEENRIFYLQAKKRMVESPL ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AEVGLPACTWPFCLATLLFLIMTTKNSNIYKMPLSKVTYPEENRIFYLQAKKRMVESPL 370 380 390 400 410 420 >>NP_001122060 (OMIM: 111000,613868) urea transporter 1 (445 aa) initn: 2629 init1: 2629 opt: 2629 Z-score: 3131.7 bits: 588.5 E(85289): 1.1e-167 Smith-Waterman score: 2629; 99.7% identity (100.0% similar) in 389 aa overlap (1-389:57-445) 10 20 30 pF1KB4 MEDSPTMVRVDSPTMVRGENQVSPCQGRRC :::::::::::::::::::::::::::::: NP_001 AGDAARRGIARLSLALADGSQEQEPEEEIAMEDSPTMVRVDSPTMVRGENQVSPCQGRRC 30 40 50 60 70 80 40 50 60 70 80 90 pF1KB4 FPKALGYVTGDMKELANQLKDKPVVLQFIDWILRGISQVVFVNNPVSGILILVGLLVQNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FPKALGYVTGDMKELANQLKDKPVVLQFIDWILRGISQVVFVNNPVSGILILVGLLVQNP 90 100 110 120 130 140 100 110 120 130 140 150 pF1KB4 WWALTGWLGTVVSTLMALLLSQDRSLIASGLYGYNATLVGVLMAVFSDKGDYFWWLLLPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WWALTGWLGTVVSTLMALLLSQDRSLIASGLYGYNATLVGVLMAVFSDKGDYFWWLLLPV 150 160 170 180 190 200 160 170 180 190 200 210 pF1KB4 CAMSMTCPIFSSALNSMLSKWDLPVFTLPFNMALSMYLSATGHYNPFFPAKLVIPITTAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CAMSMTCPIFSSALNSMLSKWDLPVFTLPFNMALSMYLSATGHYNPFFPAKLVIPITTAP 210 220 230 240 250 260 220 230 240 250 260 270 pF1KB4 NISWSDLSALELLKSIPVGVGQIYGCDNPWTGGIFLGAILLSSPLMCLHAAIGSLLGIAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NISWSDLSALELLKSIPVGVGQIYGCDNPWTGGIFLGAILLSSPLMCLHAAIGSLLGIAA 270 280 290 300 310 320 280 290 300 310 320 330 pF1KB4 GLSLSAPFENIYFGLWGFNSSLACIAMGGMFMALTWQTHLLALGCALFTAYLGVGMANFM :::::::::.:::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GLSLSAPFEDIYFGLWGFNSSLACIAMGGMFMALTWQTHLLALGCALFTAYLGVGMANFM 330 340 350 360 370 380 340 350 360 370 380 pF1KB4 AEVGLPACTWPFCLATLLFLIMTTKNSNIYKMPLSKVTYPEENRIFYLQAKKRMVESPL ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AEVGLPACTWPFCLATLLFLIMTTKNSNIYKMPLSKVTYPEENRIFYLQAKKRMVESPL 390 400 410 420 430 440 >>NP_001139509 (OMIM: 111000,613868) urea transporter 1 (445 aa) initn: 2629 init1: 2629 opt: 2629 Z-score: 3131.7 bits: 588.5 E(85289): 1.1e-167 Smith-Waterman score: 2629; 99.7% identity (100.0% similar) in 389 aa overlap (1-389:57-445) 10 20 30 pF1KB4 MEDSPTMVRVDSPTMVRGENQVSPCQGRRC :::::::::::::::::::::::::::::: NP_001 AGDAARRGIARLSLALADGSQEQEPEEEIAMEDSPTMVRVDSPTMVRGENQVSPCQGRRC 30 40 50 60 70 80 40 50 60 70 80 90 pF1KB4 FPKALGYVTGDMKELANQLKDKPVVLQFIDWILRGISQVVFVNNPVSGILILVGLLVQNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FPKALGYVTGDMKELANQLKDKPVVLQFIDWILRGISQVVFVNNPVSGILILVGLLVQNP 90 100 110 120 130 140 100 110 120 130 140 150 pF1KB4 WWALTGWLGTVVSTLMALLLSQDRSLIASGLYGYNATLVGVLMAVFSDKGDYFWWLLLPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WWALTGWLGTVVSTLMALLLSQDRSLIASGLYGYNATLVGVLMAVFSDKGDYFWWLLLPV 150 160 170 180 190 200 160 170 180 190 200 210 pF1KB4 CAMSMTCPIFSSALNSMLSKWDLPVFTLPFNMALSMYLSATGHYNPFFPAKLVIPITTAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CAMSMTCPIFSSALNSMLSKWDLPVFTLPFNMALSMYLSATGHYNPFFPAKLVIPITTAP 210 220 230 240 250 260 220 230 240 250 260 270 pF1KB4 NISWSDLSALELLKSIPVGVGQIYGCDNPWTGGIFLGAILLSSPLMCLHAAIGSLLGIAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NISWSDLSALELLKSIPVGVGQIYGCDNPWTGGIFLGAILLSSPLMCLHAAIGSLLGIAA 270 280 290 300 310 320 280 290 300 310 320 330 pF1KB4 GLSLSAPFENIYFGLWGFNSSLACIAMGGMFMALTWQTHLLALGCALFTAYLGVGMANFM :::::::::.:::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GLSLSAPFEDIYFGLWGFNSSLACIAMGGMFMALTWQTHLLALGCALFTAYLGVGMANFM 330 340 350 360 370 380 340 350 360 370 380 pF1KB4 AEVGLPACTWPFCLATLLFLIMTTKNSNIYKMPLSKVTYPEENRIFYLQAKKRMVESPL ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AEVGLPACTWPFCLATLLFLIMTTKNSNIYKMPLSKVTYPEENRIFYLQAKKRMVESPL 390 400 410 420 430 440 >>XP_005258386 (OMIM: 111000,613868) PREDICTED: urea tra (402 aa) initn: 2246 init1: 2246 opt: 2246 Z-score: 2676.4 bits: 504.1 E(85289): 2.4e-142 Smith-Waterman score: 2246; 99.7% identity (100.0% similar) in 332 aa overlap (1-332:57-388) 10 20 30 pF1KB4 MEDSPTMVRVDSPTMVRGENQVSPCQGRRC :::::::::::::::::::::::::::::: XP_005 AGDAARRGIARLSLALADGSQEQEPEEEIAMEDSPTMVRVDSPTMVRGENQVSPCQGRRC 30 40 50 60 70 80 40 50 60 70 80 90 pF1KB4 FPKALGYVTGDMKELANQLKDKPVVLQFIDWILRGISQVVFVNNPVSGILILVGLLVQNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FPKALGYVTGDMKELANQLKDKPVVLQFIDWILRGISQVVFVNNPVSGILILVGLLVQNP 90 100 110 120 130 140 100 110 120 130 140 150 pF1KB4 WWALTGWLGTVVSTLMALLLSQDRSLIASGLYGYNATLVGVLMAVFSDKGDYFWWLLLPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 WWALTGWLGTVVSTLMALLLSQDRSLIASGLYGYNATLVGVLMAVFSDKGDYFWWLLLPV 150 160 170 180 190 200 160 170 180 190 200 210 pF1KB4 CAMSMTCPIFSSALNSMLSKWDLPVFTLPFNMALSMYLSATGHYNPFFPAKLVIPITTAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 CAMSMTCPIFSSALNSMLSKWDLPVFTLPFNMALSMYLSATGHYNPFFPAKLVIPITTAP 210 220 230 240 250 260 220 230 240 250 260 270 pF1KB4 NISWSDLSALELLKSIPVGVGQIYGCDNPWTGGIFLGAILLSSPLMCLHAAIGSLLGIAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NISWSDLSALELLKSIPVGVGQIYGCDNPWTGGIFLGAILLSSPLMCLHAAIGSLLGIAA 270 280 290 300 310 320 280 290 300 310 320 330 pF1KB4 GLSLSAPFENIYFGLWGFNSSLACIAMGGMFMALTWQTHLLALGCALFTAYLGVGMANFM :::::::::.:::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GLSLSAPFEDIYFGLWGFNSSLACIAMGGMFMALTWQTHLLALGCALFTAYLGVGMANFM 330 340 350 360 370 380 340 350 360 370 380 pF1KB4 AEVGLPACTWPFCLATLLFLIMTTKNSNIYKMPLSKVTYPEENRIFYLQAKKRMVESPL :: XP_005 AEGTCERRIVGKKKQA 390 400 >>XP_011524446 (OMIM: 111000,613868) PREDICTED: urea tra (374 aa) initn: 2139 init1: 2139 opt: 2139 Z-score: 2549.5 bits: 480.5 E(85289): 2.9e-135 Smith-Waterman score: 2139; 99.7% identity (100.0% similar) in 315 aa overlap (1-315:57-371) 10 20 30 pF1KB4 MEDSPTMVRVDSPTMVRGENQVSPCQGRRC :::::::::::::::::::::::::::::: XP_011 AGDAARRGIARLSLALADGSQEQEPEEEIAMEDSPTMVRVDSPTMVRGENQVSPCQGRRC 30 40 50 60 70 80 40 50 60 70 80 90 pF1KB4 FPKALGYVTGDMKELANQLKDKPVVLQFIDWILRGISQVVFVNNPVSGILILVGLLVQNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FPKALGYVTGDMKELANQLKDKPVVLQFIDWILRGISQVVFVNNPVSGILILVGLLVQNP 90 100 110 120 130 140 100 110 120 130 140 150 pF1KB4 WWALTGWLGTVVSTLMALLLSQDRSLIASGLYGYNATLVGVLMAVFSDKGDYFWWLLLPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WWALTGWLGTVVSTLMALLLSQDRSLIASGLYGYNATLVGVLMAVFSDKGDYFWWLLLPV 150 160 170 180 190 200 160 170 180 190 200 210 pF1KB4 CAMSMTCPIFSSALNSMLSKWDLPVFTLPFNMALSMYLSATGHYNPFFPAKLVIPITTAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CAMSMTCPIFSSALNSMLSKWDLPVFTLPFNMALSMYLSATGHYNPFFPAKLVIPITTAP 210 220 230 240 250 260 220 230 240 250 260 270 pF1KB4 NISWSDLSALELLKSIPVGVGQIYGCDNPWTGGIFLGAILLSSPLMCLHAAIGSLLGIAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NISWSDLSALELLKSIPVGVGQIYGCDNPWTGGIFLGAILLSSPLMCLHAAIGSLLGIAA 270 280 290 300 310 320 280 290 300 310 320 330 pF1KB4 GLSLSAPFENIYFGLWGFNSSLACIAMGGMFMALTWQTHLLALGCALFTAYLGVGMANFM :::::::::.::::::::::::::::::::::::::::::::::: XP_011 GLSLSAPFEDIYFGLWGFNSSLACIAMGGMFMALTWQTHLLALGCGNV 330 340 350 360 370 340 350 360 370 380 pF1KB4 AEVGLPACTWPFCLATLLFLIMTTKNSNIYKMPLSKVTYPEENRIFYLQAKKRMVESPL >>NP_001295207 (OMIM: 111000,613868) urea transporter 1 (284 aa) initn: 1912 init1: 1912 opt: 1912 Z-score: 2281.0 bits: 430.4 E(85289): 2.6e-120 Smith-Waterman score: 1912; 99.6% identity (100.0% similar) in 284 aa overlap (106-389:1-284) 80 90 100 110 120 130 pF1KB4 VSGILILVGLLVQNPWWALTGWLGTVVSTLMALLLSQDRSLIASGLYGYNATLVGVLMAV :::::::::::::::::::::::::::::: NP_001 MALLLSQDRSLIASGLYGYNATLVGVLMAV 10 20 30 140 150 160 170 180 190 pF1KB4 FSDKGDYFWWLLLPVCAMSMTCPIFSSALNSMLSKWDLPVFTLPFNMALSMYLSATGHYN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FSDKGDYFWWLLLPVCAMSMTCPIFSSALNSMLSKWDLPVFTLPFNMALSMYLSATGHYN 40 50 60 70 80 90 200 210 220 230 240 250 pF1KB4 PFFPAKLVIPITTAPNISWSDLSALELLKSIPVGVGQIYGCDNPWTGGIFLGAILLSSPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PFFPAKLVIPITTAPNISWSDLSALELLKSIPVGVGQIYGCDNPWTGGIFLGAILLSSPL 100 110 120 130 140 150 260 270 280 290 300 310 pF1KB4 MCLHAAIGSLLGIAAGLSLSAPFENIYFGLWGFNSSLACIAMGGMFMALTWQTHLLALGC ::::::::::::::::::::::::.::::::::::::::::::::::::::::::::::: NP_001 MCLHAAIGSLLGIAAGLSLSAPFEDIYFGLWGFNSSLACIAMGGMFMALTWQTHLLALGC 160 170 180 190 200 210 320 330 340 350 360 370 pF1KB4 ALFTAYLGVGMANFMAEVGLPACTWPFCLATLLFLIMTTKNSNIYKMPLSKVTYPEENRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ALFTAYLGVGMANFMAEVGLPACTWPFCLATLLFLIMTTKNSNIYKMPLSKVTYPEENRI 220 230 240 250 260 270 380 pF1KB4 FYLQAKKRMVESPL :::::::::::::: NP_001 FYLQAKKRMVESPL 280 >>XP_005258390 (OMIM: 111000,613868) PREDICTED: urea tra (257 aa) initn: 1751 init1: 1751 opt: 1751 Z-score: 2089.9 bits: 394.9 E(85289): 1.1e-109 Smith-Waterman score: 1751; 99.6% identity (100.0% similar) in 257 aa overlap (133-389:1-257) 110 120 130 140 150 160 pF1KB4 STLMALLLSQDRSLIASGLYGYNATLVGVLMAVFSDKGDYFWWLLLPVCAMSMTCPIFSS :::::::::::::::::::::::::::::: XP_005 MAVFSDKGDYFWWLLLPVCAMSMTCPIFSS 10 20 30 170 180 190 200 210 220 pF1KB4 ALNSMLSKWDLPVFTLPFNMALSMYLSATGHYNPFFPAKLVIPITTAPNISWSDLSALEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ALNSMLSKWDLPVFTLPFNMALSMYLSATGHYNPFFPAKLVIPITTAPNISWSDLSALEL 40 50 60 70 80 90 230 240 250 260 270 280 pF1KB4 LKSIPVGVGQIYGCDNPWTGGIFLGAILLSSPLMCLHAAIGSLLGIAAGLSLSAPFENIY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::.:: XP_005 LKSIPVGVGQIYGCDNPWTGGIFLGAILLSSPLMCLHAAIGSLLGIAAGLSLSAPFEDIY 100 110 120 130 140 150 290 300 310 320 330 340 pF1KB4 FGLWGFNSSLACIAMGGMFMALTWQTHLLALGCALFTAYLGVGMANFMAEVGLPACTWPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FGLWGFNSSLACIAMGGMFMALTWQTHLLALGCALFTAYLGVGMANFMAEVGLPACTWPF 160 170 180 190 200 210 350 360 370 380 pF1KB4 CLATLLFLIMTTKNSNIYKMPLSKVTYPEENRIFYLQAKKRMVESPL ::::::::::::::::::::::::::::::::::::::::::::::: XP_005 CLATLLFLIMTTKNSNIYKMPLSKVTYPEENRIFYLQAKKRMVESPL 220 230 240 250 389 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 05:52:54 2016 done: Sat Nov 5 05:52:55 2016 Total Scan time: 8.380 Total Display time: 0.040 Function used was FASTA [36.3.4 Apr, 2011]