FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB4518, 338 aa 1>>>pF1KB4518 338 - 338 aa - 338 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 10.9613+/-0.0007; mu= -14.3557+/- 0.042 mean_var=349.7170+/-71.868, 0's: 0 Z-trim(110.5): 385 B-trim: 33 in 1/56 Lambda= 0.068583 statistics sampled from 18480 (18910) to 18480 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.577), E-opt: 0.2 (0.222), width: 16 Scan time: 7.050 The best scores are: opt bits E(85289) NP_001012393 (OMIM: 167000,600632) opioid-binding ( 338) 2241 236.6 5.6e-62 XP_006718909 (OMIM: 167000,600632) PREDICTED: opio ( 337) 2223 234.9 1.9e-61 NP_002536 (OMIM: 167000,600632) opioid-binding pro ( 345) 2115 224.2 3.2e-58 NP_001306035 (OMIM: 167000,600632) opioid-binding ( 344) 2097 222.4 1.1e-57 XP_011541158 (OMIM: 167000,600632) PREDICTED: opio ( 304) 2007 213.5 4.9e-55 NP_001306034 (OMIM: 167000,600632) opioid-binding ( 304) 2007 213.5 4.9e-55 NP_001306032 (OMIM: 167000,600632) opioid-binding ( 354) 1900 202.9 8.4e-52 NP_001041674 (OMIM: 607938) neurotrimin isoform 2 ( 344) 1658 179.0 1.3e-44 NP_057606 (OMIM: 607938) neurotrimin isoform 1 pre ( 344) 1629 176.1 9.7e-44 NP_001306033 (OMIM: 167000,600632) opioid-binding ( 245) 1619 175.0 1.5e-43 XP_016873353 (OMIM: 607938) PREDICTED: neurotrimin ( 325) 1616 174.8 2.3e-43 XP_016873351 (OMIM: 607938) PREDICTED: neurotrimin ( 335) 1616 174.8 2.3e-43 XP_016873350 (OMIM: 607938) PREDICTED: neurotrimin ( 335) 1616 174.8 2.3e-43 XP_016873354 (OMIM: 607938) PREDICTED: neurotrimin ( 326) 1554 168.7 1.6e-41 XP_005271639 (OMIM: 607938) PREDICTED: neurotrimin ( 355) 1554 168.7 1.7e-41 XP_005271637 (OMIM: 607938) PREDICTED: neurotrimin ( 367) 1554 168.7 1.7e-41 XP_016873344 (OMIM: 607938) PREDICTED: neurotrimin ( 373) 1554 168.7 1.8e-41 XP_016873341 (OMIM: 607938) PREDICTED: neurotrimin ( 385) 1554 168.7 1.8e-41 NP_001137531 (OMIM: 607938) neurotrimin isoform 4 ( 316) 1533 166.6 6.6e-41 XP_011541163 (OMIM: 607938) PREDICTED: neurotrimin ( 326) 1525 165.8 1.2e-40 NP_001137530 (OMIM: 607938) neurotrimin isoform 3 ( 355) 1525 165.8 1.2e-40 XP_005271638 (OMIM: 607938) PREDICTED: neurotrimin ( 367) 1525 165.8 1.3e-40 XP_016873343 (OMIM: 607938) PREDICTED: neurotrimin ( 373) 1525 165.8 1.3e-40 XP_016873340 (OMIM: 607938) PREDICTED: neurotrimin ( 385) 1525 165.8 1.3e-40 XP_006718920 (OMIM: 607938) PREDICTED: neurotrimin ( 303) 1521 165.4 1.4e-40 XP_006718918 (OMIM: 607938) PREDICTED: neurotrimin ( 346) 1512 164.5 3e-40 XP_016873347 (OMIM: 607938) PREDICTED: neurotrimin ( 346) 1512 164.5 3e-40 XP_016873348 (OMIM: 607938) PREDICTED: neurotrimin ( 346) 1512 164.5 3e-40 XP_016873346 (OMIM: 607938) PREDICTED: neurotrimin ( 358) 1512 164.5 3e-40 XP_016873345 (OMIM: 607938) PREDICTED: neurotrimin ( 358) 1512 164.5 3e-40 XP_016873342 (OMIM: 607938) PREDICTED: neurotrimin ( 376) 1512 164.6 3.2e-40 XP_016873355 (OMIM: 607938) PREDICTED: neurotrimin ( 285) 1417 155.1 1.7e-37 XP_016873352 (OMIM: 607938) PREDICTED: neurotrimin ( 332) 1417 155.1 1.9e-37 XP_016873349 (OMIM: 607938) PREDICTED: neurotrimin ( 344) 1417 155.1 2e-37 NP_002329 (OMIM: 603241) limbic system-associated ( 338) 1174 131.1 3.4e-30 XP_011511142 (OMIM: 603241) PREDICTED: limbic syst ( 344) 1134 127.1 5.4e-29 XP_016861872 (OMIM: 603241) PREDICTED: limbic syst ( 350) 1133 127.0 5.8e-29 NP_001305844 (OMIM: 603241) limbic system-associat ( 361) 1133 127.0 5.9e-29 NP_776169 (OMIM: 613173) neuronal growth regulator ( 354) 1062 120.0 7.6e-27 XP_011539502 (OMIM: 613173) PREDICTED: neuronal gr ( 320) 1032 117.0 5.5e-26 XP_011539503 (OMIM: 613173) PREDICTED: neuronal gr ( 234) 772 91.2 2.4e-18 XP_016856450 (OMIM: 613173) PREDICTED: neuronal gr ( 222) 762 90.2 4.6e-18 XP_016861873 (OMIM: 603241) PREDICTED: limbic syst ( 197) 490 63.2 5.4e-10 XP_011515761 (OMIM: 615904) PREDICTED: peroxidasin ( 757) 329 47.8 9.2e-05 XP_011508698 (OMIM: 269400,605158) PREDICTED: pero (1296) 329 47.9 0.00014 XP_011508699 (OMIM: 269400,605158) PREDICTED: pero (1296) 329 47.9 0.00014 XP_016868530 (OMIM: 615904) PREDICTED: peroxidasin (1328) 329 48.0 0.00014 XP_011515760 (OMIM: 615904) PREDICTED: peroxidasin (1328) 329 48.0 0.00014 XP_006716483 (OMIM: 615904) PREDICTED: peroxidasin (1367) 329 48.0 0.00014 XP_011515759 (OMIM: 615904) PREDICTED: peroxidasin (1439) 329 48.0 0.00015 >>NP_001012393 (OMIM: 167000,600632) opioid-binding prot (338 aa) initn: 2241 init1: 2241 opt: 2241 Z-score: 1233.6 bits: 236.6 E(85289): 5.6e-62 Smith-Waterman score: 2241; 100.0% identity (100.0% similar) in 338 aa overlap (1-338:1-338) 10 20 30 40 50 60 pF1KB4 MYHPAYWVVFSATTALLFIPGVPVRSGDATFPKAMDNVTVRQGESATLRCTIDDRVTRVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MYHPAYWVVFSATTALLFIPGVPVRSGDATFPKAMDNVTVRQGESATLRCTIDDRVTRVA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 WLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 VHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQGFVSEDEYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQGFVSEDEYL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 EISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYPPYISKAKNTGVSVGQKGILSCEAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYPPYISKAKNTGVSVGQKGILSCEAS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 AVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNA 250 260 270 280 290 300 310 320 330 pF1KB4 SITLYGPGAVIDGVNSASRALACLWLSGTLLAHFFIKF :::::::::::::::::::::::::::::::::::::: NP_001 SITLYGPGAVIDGVNSASRALACLWLSGTLLAHFFIKF 310 320 330 >>XP_006718909 (OMIM: 167000,600632) PREDICTED: opioid-b (337 aa) initn: 1126 init1: 1126 opt: 2223 Z-score: 1224.0 bits: 234.9 E(85289): 1.9e-61 Smith-Waterman score: 2223; 99.7% identity (99.7% similar) in 338 aa overlap (1-338:1-337) 10 20 30 40 50 60 pF1KB4 MYHPAYWVVFSATTALLFIPGVPVRSGDATFPKAMDNVTVRQGESATLRCTIDDRVTRVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MYHPAYWVVFSATTALLFIPGVPVRSGDATFPKAMDNVTVRQGESATLRCTIDDRVTRVA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 WLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 WLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 VHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQGFVSEDEYL :::::::::::::::::::::::::::::::::::::::::::::::: ::::::::::: XP_006 VHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVTWRHLSVK-GQGFVSEDEYL 130 140 150 160 170 190 200 210 220 230 240 pF1KB4 EISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYPPYISKAKNTGVSVGQKGILSCEAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYPPYISKAKNTGVSVGQKGILSCEAS 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB4 AVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNA 240 250 260 270 280 290 310 320 330 pF1KB4 SITLYGPGAVIDGVNSASRALACLWLSGTLLAHFFIKF :::::::::::::::::::::::::::::::::::::: XP_006 SITLYGPGAVIDGVNSASRALACLWLSGTLLAHFFIKF 300 310 320 330 >>NP_002536 (OMIM: 167000,600632) opioid-binding protein (345 aa) initn: 2111 init1: 2111 opt: 2115 Z-score: 1166.1 bits: 224.2 E(85289): 3.2e-58 Smith-Waterman score: 2115; 95.0% identity (97.1% similar) in 339 aa overlap (1-338:7-345) 10 20 30 40 50 pF1KB4 MYHPAYWVVFSATTALLFIP-GVPVRSGDATFPKAMDNVTVRQGESATLRCTID .. : .: . :...: ::::::::::::::::::::::::::::::::: NP_002 MGVCGYLFLPWKCLVVVSLRLLFLVPTGVPVRSGDATFPKAMDNVTVRQGESATLRCTID 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB4 DRVTRVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMIQNVDVYDEGPYTCSVQTD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 DRVTRVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMIQNVDVYDEGPYTCSVQTD 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB4 NHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQGF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 NHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQGF 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB4 VSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYPPYISKAKNTGVSVGQKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 VSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYPPYISKAKNTGVSVGQKG 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB4 ILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 ILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATN 250 260 270 280 290 300 300 310 320 330 pF1KB4 KLGNTNASITLYGPGAVIDGVNSASRALACLWLSGTLLAHFFIKF ::::::::::::::::::::::::::::::::::::::::::::: NP_002 KLGNTNASITLYGPGAVIDGVNSASRALACLWLSGTLLAHFFIKF 310 320 330 340 >>NP_001306035 (OMIM: 167000,600632) opioid-binding prot (344 aa) initn: 1110 init1: 1110 opt: 2097 Z-score: 1156.5 bits: 222.4 E(85289): 1.1e-57 Smith-Waterman score: 2097; 94.7% identity (96.8% similar) in 339 aa overlap (1-338:7-344) 10 20 30 40 50 pF1KB4 MYHPAYWVVFSATTALLFIP-GVPVRSGDATFPKAMDNVTVRQGESATLRCTID .. : .: . :...: ::::::::::::::::::::::::::::::::: NP_001 MGVCGYLFLPWKCLVVVSLRLLFLVPTGVPVRSGDATFPKAMDNVTVRQGESATLRCTID 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB4 DRVTRVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMIQNVDVYDEGPYTCSVQTD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DRVTRVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMIQNVDVYDEGPYTCSVQTD 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB4 NHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQGF ::::::::::::::::::::::::::::::::::::::::::::::::::::::: :::: NP_001 NHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVTWRHLSVK-GQGF 130 140 150 160 170 180 190 200 210 220 230 pF1KB4 VSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYPPYISKAKNTGVSVGQKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYPPYISKAKNTGVSVGQKG 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB4 ILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATN 240 250 260 270 280 290 300 310 320 330 pF1KB4 KLGNTNASITLYGPGAVIDGVNSASRALACLWLSGTLLAHFFIKF ::::::::::::::::::::::::::::::::::::::::::::: NP_001 KLGNTNASITLYGPGAVIDGVNSASRALACLWLSGTLLAHFFIKF 300 310 320 330 340 >>XP_011541158 (OMIM: 167000,600632) PREDICTED: opioid-b (304 aa) initn: 2007 init1: 2007 opt: 2007 Z-score: 1109.1 bits: 213.5 E(85289): 4.9e-55 Smith-Waterman score: 2007; 100.0% identity (100.0% similar) in 304 aa overlap (35-338:1-304) 10 20 30 40 50 60 pF1KB4 AYWVVFSATTALLFIPGVPVRSGDATFPKAMDNVTVRQGESATLRCTIDDRVTRVAWLNR :::::::::::::::::::::::::::::: XP_011 MDNVTVRQGESATLRCTIDDRVTRVAWLNR 10 20 30 70 80 90 100 110 120 pF1KB4 STILYAGNDKWSIDPRVIILVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 STILYAGNDKWSIDPRVIILVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLI 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB4 VQVPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQGFVSEDEYLEISD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VQVPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQGFVSEDEYLEISD 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB4 IKRDQSGEYECSALNDVAAPDVRKVKITVNYPPYISKAKNTGVSVGQKGILSCEASAVPM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IKRDQSGEYECSALNDVAAPDVRKVKITVNYPPYISKAKNTGVSVGQKGILSCEASAVPM 160 170 180 190 200 210 250 260 270 280 290 300 pF1KB4 AEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 220 230 240 250 260 270 310 320 330 pF1KB4 YGPGAVIDGVNSASRALACLWLSGTLLAHFFIKF :::::::::::::::::::::::::::::::::: XP_011 YGPGAVIDGVNSASRALACLWLSGTLLAHFFIKF 280 290 300 >>NP_001306034 (OMIM: 167000,600632) opioid-binding prot (304 aa) initn: 2007 init1: 2007 opt: 2007 Z-score: 1109.1 bits: 213.5 E(85289): 4.9e-55 Smith-Waterman score: 2007; 100.0% identity (100.0% similar) in 304 aa overlap (35-338:1-304) 10 20 30 40 50 60 pF1KB4 AYWVVFSATTALLFIPGVPVRSGDATFPKAMDNVTVRQGESATLRCTIDDRVTRVAWLNR :::::::::::::::::::::::::::::: NP_001 MDNVTVRQGESATLRCTIDDRVTRVAWLNR 10 20 30 70 80 90 100 110 120 pF1KB4 STILYAGNDKWSIDPRVIILVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 STILYAGNDKWSIDPRVIILVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLI 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB4 VQVPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQGFVSEDEYLEISD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VQVPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQGFVSEDEYLEISD 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB4 IKRDQSGEYECSALNDVAAPDVRKVKITVNYPPYISKAKNTGVSVGQKGILSCEASAVPM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IKRDQSGEYECSALNDVAAPDVRKVKITVNYPPYISKAKNTGVSVGQKGILSCEASAVPM 160 170 180 190 200 210 250 260 270 280 290 300 pF1KB4 AEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITL 220 230 240 250 260 270 310 320 330 pF1KB4 YGPGAVIDGVNSASRALACLWLSGTLLAHFFIKF :::::::::::::::::::::::::::::::::: NP_001 YGPGAVIDGVNSASRALACLWLSGTLLAHFFIKF 280 290 300 >>NP_001306032 (OMIM: 167000,600632) opioid-binding prot (354 aa) initn: 1889 init1: 1889 opt: 1900 Z-score: 1051.0 bits: 202.9 E(85289): 8.4e-52 Smith-Waterman score: 2087; 92.5% identity (94.5% similar) in 348 aa overlap (1-338:7-354) 10 20 30 40 50 pF1KB4 MYHPAYWVVFSATTALLFIP-GVPVRSGDATFPKAMDNVTVRQGESATLRCTID .. : .: . :...: ::::::::::::::::::::::::::::::::: NP_001 MGVCGYLFLPWKCLVVVSLRLLFLVPTGVPVRSGDATFPKAMDNVTVRQGESATLRCTID 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB4 DRVTRVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMIQNVDVYDEGPYTCSVQTD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DRVTRVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMIQNVDVYDEGPYTCSVQTD 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB4 NHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQGF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQGF 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB4 VSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYPPYISKAKNTGVSVGQKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYPPYISKAKNTGVSVGQKG 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB4 ILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATN 250 260 270 280 290 300 300 310 320 330 pF1KB4 KLGNTNASITLY---------GPGAVIDGVNSASRALACLWLSGTLLAHFFIKF :::::::::::: ::::::::::::::::::::::::::::::::: NP_001 KLGNTNASITLYEISPSSAVAGPGAVIDGVNSASRALACLWLSGTLLAHFFIKF 310 320 330 340 350 >>NP_001041674 (OMIM: 607938) neurotrimin isoform 2 prec (344 aa) initn: 1659 init1: 912 opt: 1658 Z-score: 921.8 bits: 179.0 E(85289): 1.3e-44 Smith-Waterman score: 1658; 71.6% identity (87.6% similar) in 338 aa overlap (1-338:8-344) 10 20 30 40 50 pF1KB4 MYHPAYWVVFSATTALLFIPGVPVRSGDATFPKAMDNVTVRQGESATLRCTID :.. :..:.. .:: .. ::::::::::::::::::::::::::::::::: NP_001 MKTIQPKMHNSISWAIFTGLAALCLFQGVPVRSGDATFPKAMDNVTVRQGESATLRCTID 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB4 DRVTRVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMIQNVDVYDEGPYTCSVQTD .::::::::::::::::::::: .::::..: :: ::::: ::::::::::::::::::: NP_001 NRVTRVAWLNRSTILYAGNDKWCLDPRVVLLSNTQTQYSIEIQNVDVYDEGPYTCSVQTD 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB4 NHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQGF :::::::::::::: :.:..:::::..:::....: :.: :::::::::::.: : . :: NP_001 NHPKTSRVHLIVQVSPKIVEISSDISINEGNNISLTCIATGRPEPTVTWRHISPK-AVGF 130 140 150 160 170 180 190 200 210 220 230 pF1KB4 VSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYPPYISKAKNTGVSVGQKG :::::::::. : :.:::.::::: :::::: ::.::.:::::::::.::.::: ::::: NP_001 VSEDEYLEIQGITREQSGDYECSASNDVAAPVVRRVKVTVNYPPYISEAKGTGVPVGQKG 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB4 ILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATN :.::::::: :::::.:.. :: : :...::. .: : ::::::.:::::::::.: NP_001 TLQCEASAVPSAEFQWYKDDKRLIEGKKGVKVENRPFLSKLIFFNVSEHDYGNYTCVASN 240 250 260 270 280 290 300 310 320 330 pF1KB4 KLGNTNASITLYGPGAVIDGVNSASRALACLWLSGTLLAHFFIKF :::.::::: :.::::: . :..:: .:.:: :. :...:: NP_001 KLGHTNASIMLFGPGAVSEVSNGTSRRAGCVWLLPLLVLHLLLKF 300 310 320 330 340 >>NP_057606 (OMIM: 607938) neurotrimin isoform 1 precurs (344 aa) initn: 1626 init1: 879 opt: 1629 Z-score: 906.3 bits: 176.1 E(85289): 9.7e-44 Smith-Waterman score: 1629; 71.1% identity (86.4% similar) in 339 aa overlap (1-338:7-344) 10 20 30 40 50 pF1KB4 MYHPAYWVVFSATTALLFIP-GVPVRSGDATFPKAMDNVTVRQGESATLRCTID .. : .: . :...: ::::::::::::::::::::::::::::::::: NP_057 MGVCGYLFLPWKCLVVVSLRLLFLVPTGVPVRSGDATFPKAMDNVTVRQGESATLRCTID 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB4 DRVTRVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMIQNVDVYDEGPYTCSVQTD .::::::::::::::::::::: .::::..: :: ::::: ::::::::::::::::::: NP_057 NRVTRVAWLNRSTILYAGNDKWCLDPRVVLLSNTQTQYSIEIQNVDVYDEGPYTCSVQTD 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB4 NHPKTSRVHLIVQVPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQGF :::::::::::::: :.:..:::::..:::....: :.: :::::::::::.: : . :: NP_057 NHPKTSRVHLIVQVSPKIVEISSDISINEGNNISLTCIATGRPEPTVTWRHISPK-AVGF 130 140 150 160 170 180 190 200 210 220 230 pF1KB4 VSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYPPYISKAKNTGVSVGQKG :::::::::. : :.:::.::::: :::::: ::.::.:::::::::.::.::: ::::: NP_057 VSEDEYLEIQGITREQSGDYECSASNDVAAPVVRRVKVTVNYPPYISEAKGTGVPVGQKG 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB4 ILSCEASAVPMAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATN :.::::::: :::::.:.. :: : :...::. .: : ::::::.:::::::::.: NP_057 TLQCEASAVPSAEFQWYKDDKRLIEGKKGVKVENRPFLSKLIFFNVSEHDYGNYTCVASN 240 250 260 270 280 290 300 310 320 330 pF1KB4 KLGNTNASITLYGPGAVIDGVNSASRALACLWLSGTLLAHFFIKF :::.::::: :.::::: . :..:: .:.:: :. :...:: NP_057 KLGHTNASIMLFGPGAVSEVSNGTSRRAGCVWLLPLLVLHLLLKF 300 310 320 330 340 >>NP_001306033 (OMIM: 167000,600632) opioid-binding prot (245 aa) initn: 1619 init1: 1619 opt: 1619 Z-score: 902.9 bits: 175.0 E(85289): 1.5e-43 Smith-Waterman score: 1619; 100.0% identity (100.0% similar) in 245 aa overlap (94-338:1-245) 70 80 90 100 110 120 pF1KB4 RSTILYAGNDKWSIDPRVIILVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHL :::::::::::::::::::::::::::::: NP_001 MIQNVDVYDEGPYTCSVQTDNHPKTSRVHL 10 20 30 130 140 150 160 170 180 pF1KB4 IVQVPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQGFVSEDEYLEIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IVQVPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVTWRHLSVKEGQGFVSEDEYLEIS 40 50 60 70 80 90 190 200 210 220 230 240 pF1KB4 DIKRDQSGEYECSALNDVAAPDVRKVKITVNYPPYISKAKNTGVSVGQKGILSCEASAVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DIKRDQSGEYECSALNDVAAPDVRKVKITVNYPPYISKAKNTGVSVGQKGILSCEASAVP 100 110 120 130 140 150 250 260 270 280 290 300 pF1KB4 MAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASIT 160 170 180 190 200 210 310 320 330 pF1KB4 LYGPGAVIDGVNSASRALACLWLSGTLLAHFFIKF ::::::::::::::::::::::::::::::::::: NP_001 LYGPGAVIDGVNSASRALACLWLSGTLLAHFFIKF 220 230 240 338 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 05:53:29 2016 done: Sat Nov 5 05:53:30 2016 Total Scan time: 7.050 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]