FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB4538, 397 aa 1>>>pF1KB4538 397 - 397 aa - 397 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.0679+/-0.000393; mu= 17.9382+/- 0.025 mean_var=67.0824+/-13.635, 0's: 0 Z-trim(111.9): 73 B-trim: 47 in 1/50 Lambda= 0.156592 statistics sampled from 20537 (20610) to 20537 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.616), E-opt: 0.2 (0.242), width: 16 Scan time: 8.230 The best scores are: opt bits E(85289) NP_001306004 (OMIM: 605581) N-acetyllactosaminide ( 397) 2707 620.8 1.8e-177 NP_006568 (OMIM: 605581) N-acetyllactosaminide bet ( 397) 2707 620.8 1.8e-177 XP_005247010 (OMIM: 615313) PREDICTED: UDP-GlcNAc: ( 328) 877 207.3 4.3e-53 NP_660279 (OMIM: 615313) UDP-GlcNAc:betaGal beta-1 ( 401) 877 207.4 5.1e-53 NP_001317421 (OMIM: 605864) N-acetyllactosaminide ( 353) 853 201.9 2e-51 NP_110392 (OMIM: 605864) N-acetyllactosaminide bet ( 378) 853 201.9 2.1e-51 NP_619651 (OMIM: 615315) acetylgalactosaminyl-O-gl ( 384) 832 197.2 5.7e-50 NP_055071 (OMIM: 605863) N-acetyllactosaminide bet ( 372) 799 189.7 9.7e-48 XP_011525928 (OMIM: 605863) PREDICTED: N-acetyllac ( 372) 799 189.7 9.7e-48 NP_940942 (OMIM: 615357) UDP-GlcNAc:betaGal beta-1 ( 397) 728 173.7 6.9e-43 XP_011525236 (OMIM: 615357) PREDICTED: UDP-GlcNAc: ( 397) 728 173.7 6.9e-43 XP_006712882 (OMIM: 603093) PREDICTED: beta-1,3-ga ( 326) 643 154.4 3.5e-37 NP_066191 (OMIM: 603093) beta-1,3-galactosyltransf ( 326) 643 154.4 3.5e-37 XP_011510387 (OMIM: 603093) PREDICTED: beta-1,3-ga ( 326) 643 154.4 3.5e-37 XP_005246988 (OMIM: 603093) PREDICTED: beta-1,3-ga ( 326) 643 154.4 3.5e-37 NP_003774 (OMIM: 603018) beta-1,3-galactosyltransf ( 422) 580 140.3 8.4e-33 XP_011511527 (OMIM: 615333) PREDICTED: lactosylcer ( 378) 557 135.1 2.8e-31 XP_011511531 (OMIM: 615333) PREDICTED: lactosylcer ( 378) 557 135.1 2.8e-31 XP_005247882 (OMIM: 615333) PREDICTED: lactosylcer ( 378) 557 135.1 2.8e-31 XP_011511528 (OMIM: 615333) PREDICTED: lactosylcer ( 378) 557 135.1 2.8e-31 XP_011511529 (OMIM: 615333) PREDICTED: lactosylcer ( 378) 557 135.1 2.8e-31 XP_011511530 (OMIM: 615333) PREDICTED: lactosylcer ( 378) 557 135.1 2.8e-31 XP_005247881 (OMIM: 615333) PREDICTED: lactosylcer ( 378) 557 135.1 2.8e-31 XP_005247880 (OMIM: 615333) PREDICTED: lactosylcer ( 378) 557 135.1 2.8e-31 XP_016862798 (OMIM: 615333) PREDICTED: lactosylcer ( 378) 557 135.1 2.8e-31 NP_114436 (OMIM: 615333) lactosylceramide 1,3-N-ac ( 378) 557 135.1 2.8e-31 XP_016883729 (OMIM: 604066) PREDICTED: beta-1,3-ga ( 310) 483 118.3 2.6e-26 XP_016883718 (OMIM: 604066) PREDICTED: beta-1,3-ga ( 310) 483 118.3 2.6e-26 XP_016883723 (OMIM: 604066) PREDICTED: beta-1,3-ga ( 310) 483 118.3 2.6e-26 XP_016883730 (OMIM: 604066) PREDICTED: beta-1,3-ga ( 310) 483 118.3 2.6e-26 XP_016883721 (OMIM: 604066) PREDICTED: beta-1,3-ga ( 310) 483 118.3 2.6e-26 XP_016883722 (OMIM: 604066) PREDICTED: beta-1,3-ga ( 310) 483 118.3 2.6e-26 XP_016883716 (OMIM: 604066) PREDICTED: beta-1,3-ga ( 310) 483 118.3 2.6e-26 XP_016883727 (OMIM: 604066) PREDICTED: beta-1,3-ga ( 310) 483 118.3 2.6e-26 XP_016883724 (OMIM: 604066) PREDICTED: beta-1,3-ga ( 310) 483 118.3 2.6e-26 NP_149360 (OMIM: 604066) beta-1,3-galactosyltransf ( 310) 483 118.3 2.6e-26 NP_006048 (OMIM: 604066) beta-1,3-galactosyltransf ( 310) 483 118.3 2.6e-26 XP_016883720 (OMIM: 604066) PREDICTED: beta-1,3-ga ( 310) 483 118.3 2.6e-26 NP_001265579 (OMIM: 604066) beta-1,3-galactosyltra ( 310) 483 118.3 2.6e-26 XP_016883728 (OMIM: 604066) PREDICTED: beta-1,3-ga ( 310) 483 118.3 2.6e-26 XP_016883726 (OMIM: 604066) PREDICTED: beta-1,3-ga ( 310) 483 118.3 2.6e-26 XP_016883717 (OMIM: 604066) PREDICTED: beta-1,3-ga ( 310) 483 118.3 2.6e-26 NP_149361 (OMIM: 604066) beta-1,3-galactosyltransf ( 310) 483 118.3 2.6e-26 XP_016883725 (OMIM: 604066) PREDICTED: beta-1,3-ga ( 310) 483 118.3 2.6e-26 XP_016883719 (OMIM: 604066) PREDICTED: beta-1,3-ga ( 310) 483 118.3 2.6e-26 NP_149362 (OMIM: 604066) beta-1,3-galactosyltransf ( 314) 483 118.3 2.6e-26 XP_005247918 (OMIM: 111400,603094,615021) PREDICTE ( 331) 438 108.1 3.1e-23 NP_149357 (OMIM: 111400,603094,615021) UDP-GalNAc: ( 331) 438 108.1 3.1e-23 XP_006713866 (OMIM: 111400,603094,615021) PREDICTE ( 331) 438 108.1 3.1e-23 NP_001033717 (OMIM: 111400,603094,615021) UDP-GalN ( 331) 438 108.1 3.1e-23 >>NP_001306004 (OMIM: 605581) N-acetyllactosaminide beta (397 aa) initn: 2707 init1: 2707 opt: 2707 Z-score: 3307.2 bits: 620.8 E(85289): 1.8e-177 Smith-Waterman score: 2707; 100.0% identity (100.0% similar) in 397 aa overlap (1-397:1-397) 10 20 30 40 50 60 pF1KB4 MSVGRRRIKLLGILMMANVFIYFIMEVSKSSSQEKNGKGEVIIPKEKFWKISTPPEAYWN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSVGRRRIKLLGILMMANVFIYFIMEVSKSSSQEKNGKGEVIIPKEKFWKISTPPEAYWN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 REQEKLNRQYNPILSMLTNQTGEAGRLSNISHLNYCEPDLRVTSVVTGFNNLPDRFKDFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 REQEKLNRQYNPILSMLTNQTGEAGRLSNISHLNYCEPDLRVTSVVTGFNNLPDRFKDFL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 LYLRCRNYSLLIDQPDKCAKKPFLLLAIKSLTPHFARRQAIRESWGQESNAGNQTVVRVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LYLRCRNYSLLIDQPDKCAKKPFLLLAIKSLTPHFARRQAIRESWGQESNAGNQTVVRVF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 LLGQTPPEDNHPDLSDMLKFESEKHQDILMWNYRDTFFNLSLKEVLFLRWVSTSCPDTEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLGQTPPEDNHPDLSDMLKFESEKHQDILMWNYRDTFFNLSLKEVLFLRWVSTSCPDTEF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 VFKGDDDVFVNTHHILNYLNSLSKTKAKDLFIGDVIHNAGPHRDKKLKYYIPEVVYSGLY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VFKGDDDVFVNTHHILNYLNSLSKTKAKDLFIGDVIHNAGPHRDKKLKYYIPEVVYSGLY 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 PPYAGGGGFLYSGHLALRLYHITDQVHLYPIDDVYTGMCLQKLGLVPEKHKGFRTFDIEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PPYAGGGGFLYSGHLALRLYHITDQVHLYPIDDVYTGMCLQKLGLVPEKHKGFRTFDIEE 310 320 330 340 350 360 370 380 390 pF1KB4 KNKNNICSYVDLMLVHSRKPQEMIDIWSQLQSAHLKC ::::::::::::::::::::::::::::::::::::: NP_001 KNKNNICSYVDLMLVHSRKPQEMIDIWSQLQSAHLKC 370 380 390 >>NP_006568 (OMIM: 605581) N-acetyllactosaminide beta-1, (397 aa) initn: 2707 init1: 2707 opt: 2707 Z-score: 3307.2 bits: 620.8 E(85289): 1.8e-177 Smith-Waterman score: 2707; 100.0% identity (100.0% similar) in 397 aa overlap (1-397:1-397) 10 20 30 40 50 60 pF1KB4 MSVGRRRIKLLGILMMANVFIYFIMEVSKSSSQEKNGKGEVIIPKEKFWKISTPPEAYWN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 MSVGRRRIKLLGILMMANVFIYFIMEVSKSSSQEKNGKGEVIIPKEKFWKISTPPEAYWN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 REQEKLNRQYNPILSMLTNQTGEAGRLSNISHLNYCEPDLRVTSVVTGFNNLPDRFKDFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 REQEKLNRQYNPILSMLTNQTGEAGRLSNISHLNYCEPDLRVTSVVTGFNNLPDRFKDFL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 LYLRCRNYSLLIDQPDKCAKKPFLLLAIKSLTPHFARRQAIRESWGQESNAGNQTVVRVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 LYLRCRNYSLLIDQPDKCAKKPFLLLAIKSLTPHFARRQAIRESWGQESNAGNQTVVRVF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 LLGQTPPEDNHPDLSDMLKFESEKHQDILMWNYRDTFFNLSLKEVLFLRWVSTSCPDTEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 LLGQTPPEDNHPDLSDMLKFESEKHQDILMWNYRDTFFNLSLKEVLFLRWVSTSCPDTEF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 VFKGDDDVFVNTHHILNYLNSLSKTKAKDLFIGDVIHNAGPHRDKKLKYYIPEVVYSGLY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 VFKGDDDVFVNTHHILNYLNSLSKTKAKDLFIGDVIHNAGPHRDKKLKYYIPEVVYSGLY 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 PPYAGGGGFLYSGHLALRLYHITDQVHLYPIDDVYTGMCLQKLGLVPEKHKGFRTFDIEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 PPYAGGGGFLYSGHLALRLYHITDQVHLYPIDDVYTGMCLQKLGLVPEKHKGFRTFDIEE 310 320 330 340 350 360 370 380 390 pF1KB4 KNKNNICSYVDLMLVHSRKPQEMIDIWSQLQSAHLKC ::::::::::::::::::::::::::::::::::::: NP_006 KNKNNICSYVDLMLVHSRKPQEMIDIWSQLQSAHLKC 370 380 390 >>XP_005247010 (OMIM: 615313) PREDICTED: UDP-GlcNAc:beta (328 aa) initn: 669 init1: 294 opt: 877 Z-score: 1074.1 bits: 207.3 E(85289): 4.3e-53 Smith-Waterman score: 877; 43.3% identity (73.5% similar) in 298 aa overlap (109-397:28-321) 80 90 100 110 120 130 pF1KB4 NQTGEAGRLSNISHLNYCEPDLRVTSVVTGFNNLPDRFKDFLLYLRCRNYSLLIDQPDKC :. : .:..::.: .:: . .:...:.:: XP_005 MASQGPQAWDVTTTNCSANINLTHQPWFQVLEPQFRQFLFYRHCRYFPMLLNHPEKC 10 20 30 40 50 140 150 160 170 180 190 pF1KB4 AKKPFLLLAIKSLTPHFARRQAIRESWGQE--SNAGNQTVVR-VFLLGQTPPEDNHPDLS .::...::. . ::.:::..::.: : .:.. .:: .:::: . .... . XP_005 RGDVYLLVVVKSVITQHDRREAIRQTWGRERQSAGGGRGAVRTLFLLGTASKQEERTHYQ 60 70 80 90 100 110 200 210 220 230 240 250 pF1KB4 DMLKFESEKHQDILMWNYRDTFFNLSLKEVLFLRWVSTSCPDTEFVFKGDDDVFVNTHHI ..: .:.. . :::.:.. ::::::.:::. ::.:.. :: . :.:::::::::: .. XP_005 QLLAYEDRLYGDILQWGFLDTFFNLTLKEIHFLKWLDIYCPHVPFIFKGDDDVFVNPTNL 120 130 140 150 160 170 260 270 280 290 300 310 pF1KB4 LNYLNSLSKTKAKDLFIGDVIHNAGPHRDKKLKYYIPEVVYS-GLYPPYAGGGGFLYSGH :..: . . ..::.:::...: : : : ::::: ..:. . :::::::::::..: XP_005 LEFLAD--RQPQENLFVGDVLQHARPIRRKDNKYYIPGALYGKASYPPYAGGGGFLMAGS 180 190 200 210 220 230 320 330 340 350 360 pF1KB4 LALRLYHITDQVHLYPIDDVYTGMCLQKLGLVPEKHKGFRTFDIEEKNKNN-----ICSY :: ::.: : ..:::::::. ::::. ::. : :.::.:: : .:.:. : . XP_005 LARRLHHACDTLELYPIDDVFLGMCLEVLGVQPTAHEGFKTFGIS-RNRNSRMNKEPCFF 240 250 260 270 280 290 370 380 390 pF1KB4 VDLMLVHSRKPQEMIDIWSQLQSAHLKC ...::. : :.. .:. ..: .: : XP_005 RAMLVVHKLLPPELLAMWGLVHS-NLTCSRKLQVL 300 310 320 >>NP_660279 (OMIM: 615313) UDP-GlcNAc:betaGal beta-1,3-N (401 aa) initn: 669 init1: 294 opt: 877 Z-score: 1072.9 bits: 207.4 E(85289): 5.1e-53 Smith-Waterman score: 878; 37.8% identity (67.9% similar) in 368 aa overlap (47-397:33-394) 20 30 40 50 60 70 pF1KB4 ANVFIYFIMEVSKSSSQEKNGKGEVIIPKEKFWKISTPPEAYWNREQEKLNRQYNPI--- .: . :: .. :. .. :: NP_660 LWKKTVYRSLCLALALLVAVTVFQRSLTPGQFLQEPPPPTLEPQKAQKPNGQLVNPNNFW 10 20 30 40 50 60 80 90 100 110 120 pF1KB4 -----LSMLTNQTGEAGRLSNISHLNYCEPDLRVTSVVTGFNNLPDRFKDFLLYLRCRNY .. : ..... . ... : : .. .: :. : .:..::.: .:: . NP_660 KNPKDVAAPTPMASQGPQAWDVTTTN-CSANINLTHQ-PWFQVLEPQFRQFLFYRHCRYF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 SLLIDQPDKCAKKPFLLLAIKSLTPHFARRQAIRESWGQE--SNAGNQTVVR-VFLLGQT .:...:.:: .::...::. . ::.:::..::.: : .:.. .:: .:::: . NP_660 PMLLNHPEKCRGDVYLLVVVKSVITQHDRREAIRQTWGRERQSAGGGRGAVRTLFLLGTA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 PPEDNHPDLSDMLKFESEKHQDILMWNYRDTFFNLSLKEVLFLRWVSTSCPDTEFVFKGD .... ...: .:.. . :::.:.. ::::::.:::. ::.:.. :: . :.:::: NP_660 SKQEERTHYQQLLAYEDRLYGDILQWGFLDTFFNLTLKEIHFLKWLDIYCPHVPFIFKGD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 DDVFVNTHHILNYLNSLSKTKAKDLFIGDVIHNAGPHRDKKLKYYIPEVVYS-GLYPPYA :::::: ..:..: .. ..::.:::...: : : : ::::: ..:. . ::::: NP_660 DDVFVNPTNLLEFLA--DRQPQENLFVGDVLQHARPIRRKDNKYYIPGALYGKASYPPYA 250 260 270 280 290 310 320 330 340 350 360 pF1KB4 GGGGFLYSGHLALRLYHITDQVHLYPIDDVYTGMCLQKLGLVPEKHKGFRTFDIEEKNKN ::::::..: :: ::.: : ..:::::::. ::::. ::. : :.::.:: : .:.: NP_660 GGGGFLMAGSLARRLHHACDTLELYPIDDVFLGMCLEVLGVQPTAHEGFKTFGIS-RNRN 300 310 320 330 340 350 370 380 390 pF1KB4 N-----ICSYVDLMLVHSRKPQEMIDIWSQLQSAHLKC . : . ...::. : :.. .:. ..: .: : NP_660 SRMNKEPCFFRAMLVVHKLLPPELLAMWGLVHS-NLTCSRKLQVL 360 370 380 390 400 >>NP_001317421 (OMIM: 605864) N-acetyllactosaminide beta (353 aa) initn: 759 init1: 244 opt: 853 Z-score: 1044.3 bits: 201.9 E(85289): 2e-51 Smith-Waterman score: 853; 43.5% identity (72.1% similar) in 308 aa overlap (96-397:51-345) 70 80 90 100 110 120 pF1KB4 LNRQYNPILSMLTNQTGEAGRLSNISHLNYCEPDLRVTSVVTGFNNLPDRFKDFLLYLRC : :. :.:. .::.: . :: : .: NP_001 LLFLRKAAKPAGDPTAHQPFWAPPTPRHSRCPPNHTVSSASL---SLPSRHRLFLTYRHC 30 40 50 60 70 130 140 150 160 170 180 pF1KB4 RNYSLLIDQPDKCAKKPFLLLAIKSLTPHFARRQAIRESWGQESN-AGNQTVVRVFLLG- ::.:.:.. :. :.: :::::::: : :: ::: .::. .. : .. . ::::: NP_001 RNFSILLE-PSGCSKDTFLLLAIKSQPGHVERRAAIRSTWGRVGGWARGRQLKLVFLLGV 80 90 100 110 120 130 190 200 210 220 230 240 pF1KB4 --QTPPEDNHPDLSDMLKFESEKHQDILMWNYRDTFFNLSLKEVLFLRWVSTSCPDTEFV ..:: ...: .::.. .:::.:.. . ::::.:::. . ::: ..::...:. NP_001 AGSAPP-------AQLLAYESREFDDILQWDFTEDFFNLTLKELHLQRWVVAACPQAHFM 140 150 160 170 180 250 260 270 280 290 300 pF1KB4 FKGDDDVFVNTHHILNYLNSLSKTKAKDLFIGDVIHNAGPHRDKKLKYYIPEVVYSGL-Y .::::::::.. ..:..:.. . :.::..::::..: :.:. :.::.:: .: . : NP_001 LKGDDDVFVHVPNVLEFLDGWDP--AQDLLVGDVIRQALPNRNTKVKYFIPPSMYRATHY 190 200 210 220 230 240 310 320 330 340 350 360 pF1KB4 PPYAGGGGFLYSGHLALRLYHITDQVHLYPIDDVYTGMCLQKLGLVPEKHKGFRTFDIEE ::::::::...: . :: : ....:.:::::..::::..::: : .: ::.:: :.. NP_001 PPYAGGGGYVMSRATVRRLQAIMEDAELFPIDDVFVGMCLRRLGLSPMHHAGFKTFGIRR 250 260 270 280 290 300 370 380 390 pF1KB4 K-NKNNICSYVDLMLVHSRKPQEMIDIWSQLQSAHLKC . . : : :.::: .: :: .:. . . ::: NP_001 PLDPLDPCLYRGLLLVHRLSPLEMWTMWALVTDEGLKCAAGPIPQR 310 320 330 340 350 >>NP_110392 (OMIM: 605864) N-acetyllactosaminide beta-1, (378 aa) initn: 759 init1: 244 opt: 853 Z-score: 1043.9 bits: 201.9 E(85289): 2.1e-51 Smith-Waterman score: 853; 43.5% identity (72.1% similar) in 308 aa overlap (96-397:76-370) 70 80 90 100 110 120 pF1KB4 LNRQYNPILSMLTNQTGEAGRLSNISHLNYCEPDLRVTSVVTGFNNLPDRFKDFLLYLRC : :. :.:. .::.: . :: : .: NP_110 LLFLRKAAKPAGDPTAHQPFWAPPTPRHSRCPPNHTVSSASL---SLPSRHRLFLTYRHC 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB4 RNYSLLIDQPDKCAKKPFLLLAIKSLTPHFARRQAIRESWGQESN-AGNQTVVRVFLLG- ::.:.:.. :. :.: :::::::: : :: ::: .::. .. : .. . ::::: NP_110 RNFSILLE-PSGCSKDTFLLLAIKSQPGHVERRAAIRSTWGRVGGWARGRQLKLVFLLGV 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB4 --QTPPEDNHPDLSDMLKFESEKHQDILMWNYRDTFFNLSLKEVLFLRWVSTSCPDTEFV ..:: ...: .::.. .:::.:.. . ::::.:::. . ::: ..::...:. NP_110 AGSAPP-------AQLLAYESREFDDILQWDFTEDFFNLTLKELHLQRWVVAACPQAHFM 170 180 190 200 210 250 260 270 280 290 300 pF1KB4 FKGDDDVFVNTHHILNYLNSLSKTKAKDLFIGDVIHNAGPHRDKKLKYYIPEVVYSGL-Y .::::::::.. ..:..:.. . :.::..::::..: :.:. :.::.:: .: . : NP_110 LKGDDDVFVHVPNVLEFLDGWDP--AQDLLVGDVIRQALPNRNTKVKYFIPPSMYRATHY 220 230 240 250 260 270 310 320 330 340 350 360 pF1KB4 PPYAGGGGFLYSGHLALRLYHITDQVHLYPIDDVYTGMCLQKLGLVPEKHKGFRTFDIEE ::::::::...: . :: : ....:.:::::..::::..::: : .: ::.:: :.. NP_110 PPYAGGGGYVMSRATVRRLQAIMEDAELFPIDDVFVGMCLRRLGLSPMHHAGFKTFGIRR 280 290 300 310 320 330 370 380 390 pF1KB4 K-NKNNICSYVDLMLVHSRKPQEMIDIWSQLQSAHLKC . . : : :.::: .: :: .:. . . ::: NP_110 PLDPLDPCLYRGLLLVHRLSPLEMWTMWALVTDEGLKCAAGPIPQR 340 350 360 370 >>NP_619651 (OMIM: 615315) acetylgalactosaminyl-O-glycos (384 aa) initn: 756 init1: 227 opt: 832 Z-score: 1018.2 bits: 197.2 E(85289): 5.7e-50 Smith-Waterman score: 832; 41.3% identity (70.8% similar) in 298 aa overlap (109-397:82-377) 80 90 100 110 120 130 pF1KB4 NQTGEAGRLSNISHLNYCEPDLRVTSVVTGFNNLPDRFKDFLLYLRCRNYSLLIDQPDKC :..:: :..::: : .::.. :: : : :: NP_619 TDAPAADEPPSELVPGPPCVANASANATADFEQLPARIQDFLRYRHCRHFPLLWDAPAKC 60 70 80 90 100 110 140 150 160 170 180 190 pF1KB4 A--KKPFLLLAIKSLTPHFARRQAIRESWGQESNAGNQTVVRVFLLGQTPPEDNH--PDL : . :::::.:: :. ::. ::..:::: . :.. : :.:::: :::. : NP_619 AGGRGVFLLLAVKSAPEHYERRELIRRTWGQERSYGGRPVRRLFLLGTPGPEDEARAERL 120 130 140 150 160 170 200 210 220 230 240 250 pF1KB4 SDMLKFESEKHQDILMWNYRDTFFNLSLKEVLFLRWVSTSCPDTEFVFKGDDDVFVNTHH .... .:...: :.:.: . :::.::.::.. .: :... :: ..:...:::::::.: . NP_619 AELVALEAREHGDVLQWAFADTFLNLTLKHLHLLDWLAARCPHARFLLSGDDDVFVHTAN 180 190 200 210 220 230 260 270 280 290 300 310 pF1KB4 ILNYLNSLSKTKAKDLFIGDVIHNAGPHRDKKLKYYIPEVVYSG-LYPPYAGGGGFLYSG .. .:.. . .. :: :...... : ::. ::..: .. : :: : .::::: :: NP_619 VVRFLQA--QPPGRHLFSGQLMEGSVPIRDSWSKYFVPPQLFPGSAYPVYCSGGGFLLSG 240 250 260 270 280 320 330 340 350 360 pF1KB4 HLALRLYHITDQVHLYPIDDVYTGMCLQKLGLVPEKHKGFRTFDIE----EKNKNNICSY : : . .. :.::::.: ::::.. ::.: :.:.: : .. .... . : : NP_619 PTARALRAAARHTPLFPIDDAYMGMCLERAGLAPSGHEGIRPFGVQLPGAQQSSFDPCMY 290 300 310 320 330 340 370 380 390 pF1KB4 VDLMLVHSRKPQEMIDIWSQLQSAHLKC .:.::: : ::. .:. :.: :.: NP_619 RELLLVHRFAPYEMLLMWKALHSPALSCDRGHRVS 350 360 370 380 >>NP_055071 (OMIM: 605863) N-acetyllactosaminide beta-1, (372 aa) initn: 739 init1: 372 opt: 799 Z-score: 978.1 bits: 189.7 E(85289): 9.7e-48 Smith-Waterman score: 799; 41.3% identity (70.0% similar) in 303 aa overlap (103-397:65-365) 80 90 100 110 120 130 pF1KB4 ILSMLTNQTGEAGRLSNISHLNYCEPDLRVTSVVT--GFNNLPDRFKDFLLYLRCRNYSL ::.:: : . :.. ..:::: .::.. : NP_055 KVQEQPPAIPEALAWPTPPTRPAPAPCHANTSMVTHPDFATQPQHVQNFLLYRHCRHFPL 40 50 60 70 80 90 140 150 160 170 180 pF1KB4 LID-QPDKCAKKPFLLLAIKSLTPHFARRQAIRESWGQESNAGNQTVVRVFLLGQTPPED : : :.:::. ::::.::: ...::. .:..::.: .. . . .::.: . NP_055 LQDVPPSKCAQPVFLLLVIKSSPSNYVRRELLRRTWGRERKVRGLQLRLLFLVGTASNPH 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB4 NHPDLSDMLKFESEKHQDILMWNYRDTFFNLSLKEVLFLRWVSTSCPDTEFVFKGDDDVF . .. .:..:.. : :::.:...:.::::.::.::::.: : : .. ::..:::::: NP_055 EARKVNRLLELEAQTHGDILQWDFHDSFFNLTLKQVLFLQWQETRCANASFVLNGDDDVF 160 170 180 190 200 210 250 260 270 280 290 300 pF1KB4 VNTHHILNYLNSLSKTKAKDLFIGDVIHNAGPHRDKKLKYYIPEVVYSGL-YPPYAGGGG ..: ... ::. .. .. ::.:..:.:.:: : :::.:::: .. :::: :::: NP_055 AHTDNMVFYLQ--DHDPGRHLFVGQLIQNVGPIRAFWSKYYVPEVVTQNERYPPYCGGGG 220 230 240 250 260 270 310 320 330 340 350 360 pF1KB4 FLYSGHLALRLYHITDQVHLYPIDDVYTGMCLQKLGLVPEKHKGFRTFDIEEKNKN---- :: : : : . . . ..:::::. ::::. :: : .:.:.:: .. .. NP_055 FLLSRFTAAALRRAAHVLDIFPIDDVFLGMCLELEGLKPASHSGIRTSGVRAPSQRLSSF 280 290 300 310 320 330 370 380 390 pF1KB4 NICSYVDLMLVHSRKPQEMIDIWSQLQSAHLKC . : : ::.::: : ::. .:. :.. .: : NP_055 DPCFYRDLLLVHRFLPYEMLLMWDALNQPNLTCGNQTQIY 340 350 360 370 >>XP_011525928 (OMIM: 605863) PREDICTED: N-acetyllactosa (372 aa) initn: 739 init1: 372 opt: 799 Z-score: 978.1 bits: 189.7 E(85289): 9.7e-48 Smith-Waterman score: 799; 41.3% identity (70.0% similar) in 303 aa overlap (103-397:65-365) 80 90 100 110 120 130 pF1KB4 ILSMLTNQTGEAGRLSNISHLNYCEPDLRVTSVVT--GFNNLPDRFKDFLLYLRCRNYSL ::.:: : . :.. ..:::: .::.. : XP_011 KVQEQPPAIPEALAWPTPPTRPAPAPCHANTSMVTHPDFATQPQHVQNFLLYRHCRHFPL 40 50 60 70 80 90 140 150 160 170 180 pF1KB4 LID-QPDKCAKKPFLLLAIKSLTPHFARRQAIRESWGQESNAGNQTVVRVFLLGQTPPED : : :.:::. ::::.::: ...::. .:..::.: .. . . .::.: . XP_011 LQDVPPSKCAQPVFLLLVIKSSPSNYVRRELLRRTWGRERKVRGLQLRLLFLVGTASNPH 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB4 NHPDLSDMLKFESEKHQDILMWNYRDTFFNLSLKEVLFLRWVSTSCPDTEFVFKGDDDVF . .. .:..:.. : :::.:...:.::::.::.::::.: : : .. ::..:::::: XP_011 EARKVNRLLELEAQTHGDILQWDFHDSFFNLTLKQVLFLQWQETRCANASFVLNGDDDVF 160 170 180 190 200 210 250 260 270 280 290 300 pF1KB4 VNTHHILNYLNSLSKTKAKDLFIGDVIHNAGPHRDKKLKYYIPEVVYSGL-YPPYAGGGG ..: ... ::. .. .. ::.:..:.:.:: : :::.:::: .. :::: :::: XP_011 AHTDNMVFYLQ--DHDPGRHLFVGQLIQNVGPIRAFWSKYYVPEVVTQNERYPPYCGGGG 220 230 240 250 260 270 310 320 330 340 350 360 pF1KB4 FLYSGHLALRLYHITDQVHLYPIDDVYTGMCLQKLGLVPEKHKGFRTFDIEEKNKN---- :: : : : . . . ..:::::. ::::. :: : .:.:.:: .. .. XP_011 FLLSRFTAAALRRAAHVLDIFPIDDVFLGMCLELEGLKPASHSGIRTSGVRAPSQRLSSF 280 290 300 310 320 330 370 380 390 pF1KB4 NICSYVDLMLVHSRKPQEMIDIWSQLQSAHLKC . : : ::.::: : ::. .:. :.. .: : XP_011 DPCFYRDLLLVHRFLPYEMLLMWDALNQPNLTCGNQTQIY 340 350 360 370 >>NP_940942 (OMIM: 615357) UDP-GlcNAc:betaGal beta-1,3-N (397 aa) initn: 719 init1: 495 opt: 728 Z-score: 891.0 bits: 173.7 E(85289): 6.9e-43 Smith-Waterman score: 746; 34.5% identity (65.8% similar) in 351 aa overlap (55-397:69-397) 30 40 50 60 70 80 pF1KB4 MEVSKSSSQEKNGKGEVIIPKEKFWKISTPPEAYWNREQEKLNRQYNPILSMLTNQTGEA : ::::..: .:. :. .... :. NP_940 RGTPPSPTPANPEPTLPANLSTRLGQTIPLPFAYWNQQQWRLG-------SLPSGDSTET 40 50 60 70 80 90 90 100 110 120 130 pF1KB4 GRLSNISHLNYCEP-DLRVTSVVTGFNNLPDRFKDFLLYLRCRNYSLLI-----DQPDKC : :. ... . : . : .. ::: ::.. . .: ..: NP_940 GG---------CQAWGAAAATEIPDFASYPKDLRRFLLSAACRSFPQWLPGGGGSQVSSC 100 110 120 130 140 140 150 160 170 180 190 pF1KB4 AKK--PFLLLAIKSLTPHFARRQAIRESWGQESNAGNQTVVRVFLLGQTPPEDNHPDLSD . :.::::.:: .::.:::.::.::. . . . .:::: .: . :::.. NP_940 SDTDVPYLLLAVKSEPGRFAERQAVRETWGSPAPG----IRLLFLLG-SPVGEAGPDLDS 150 160 170 180 190 200 210 220 230 240 250 pF1KB4 MLKFESEKHQDILMWNYRDTFFNLSLKEVLFLRWVSTSCPDTEFVFKGDDDVFVNTHHIL .. .::....:.:.:.. :. :: .::..:.: :.. :: . ::....::.::.: .: NP_940 LVAWESRRYSDLLLWDFLDVPFNQTLKDLLLLAWLGRHCPTVSFVLRAQDDAFVHTPALL 200 210 220 230 240 250 260 270 280 290 300 310 pF1KB4 NYLNSLSKTKAKDLFIGDVIHNAGPHRDKKLKYYIPEVVYSGLYPPYAGGGGFLYSGHLA .: .: ..:..:..:.:. .: : : .:.:: . : :: ::.:::.. .:.:: NP_940 AHLRALPPASARSLYLGEVFTQAMPLRKPGGPFYVPESFFEGGYPAYASGGGYVIAGRLA 260 270 280 290 300 310 320 330 340 350 360 370 pF1KB4 LRLYHITDQVHLYPIDDVYTGMCLQKLGLVPEKHKGFRTFDIEEKNKNNICSYVDLMLVH : . . .: .:..:::::.:.. :::::. : :: : ... .. :.. .:.::. NP_940 PWLLRAAARVAPFPFEDVYTGLCIRALGLVPQAHPGFLTAWPADRTADH-CAFRNLLLVR 320 330 340 350 360 370 380 390 pF1KB4 SRKPQEMIDIWSQLQSAHLKC :: : .:.:::. .:.: NP_940 PLGPQASIRLWKQLQDPRLQC 380 390 397 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 05:54:12 2016 done: Sat Nov 5 05:54:13 2016 Total Scan time: 8.230 Total Display time: 0.040 Function used was FASTA [36.3.4 Apr, 2011]