FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB4540, 348 aa 1>>>pF1KB4540 348 - 348 aa - 348 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.4012+/-0.000933; mu= 18.2915+/- 0.057 mean_var=113.9698+/-22.545, 0's: 0 Z-trim(110.1): 38 B-trim: 216 in 1/49 Lambda= 0.120138 statistics sampled from 11317 (11351) to 11317 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.71), E-opt: 0.2 (0.349), width: 16 Scan time: 2.230 The best scores are: opt bits E(32554) CCDS4271.1 RNF14 gene_id:9604|Hs108|chr5 ( 348) 2468 438.3 4.4e-123 CCDS4270.1 RNF14 gene_id:9604|Hs108|chr5 ( 474) 2468 438.5 5.3e-123 CCDS47639.1 ANKIB1 gene_id:54467|Hs108|chr7 (1089) 336 69.4 1.6e-11 >>CCDS4271.1 RNF14 gene_id:9604|Hs108|chr5 (348 aa) initn: 2468 init1: 2468 opt: 2468 Z-score: 2323.3 bits: 438.3 E(32554): 4.4e-123 Smith-Waterman score: 2468; 100.0% identity (100.0% similar) in 348 aa overlap (1-348:1-348) 10 20 30 40 50 60 pF1KB4 MQFLKEETLAYLNIVSPFELKIGSQKKVQRRTAQASPNTELDFGGAAGSDVDQEEIVDER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 MQFLKEETLAYLNIVSPFELKIGSQKKVQRRTAQASPNTELDFGGAAGSDVDQEEIVDER 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 AVQDVESLSNLIQEILDFDQAQQIKCFNSKLFLCSICFCEKLGSECMYFLECRHVYCKAC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 AVQDVESLSNLIQEILDFDQAQQIKCFNSKLFLCSICFCEKLGSECMYFLECRHVYCKAC 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 LKDYFEIQIRDGQVQCLNCPEPKCPSVATPGQVKELVEAELFARYDRLLLQSSLDLMADV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 LKDYFEIQIRDGQVQCLNCPEPKCPSVATPGQVKELVEAELFARYDRLLLQSSLDLMADV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 VYCPRPCCQLPVMQEPGCTMGICSSCNFAFCTLCRLTYHGVSPCKVTAEKLMDLRNEYLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 VYCPRPCCQLPVMQEPGCTMGICSSCNFAFCTLCRLTYHGVSPCKVTAEKLMDLRNEYLQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 ADEANKRLLDQRYGKRVIQKALEEMESKEWLEKNSKSCPCCGTPIEKLDGCNKMTCTGCM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 ADEANKRLLDQRYGKRVIQKALEEMESKEWLEKNSKSCPCCGTPIEKLDGCNKMTCTGCM 250 260 270 280 290 300 310 320 330 340 pF1KB4 QYFCWICMGSLSRANPYKHFNDPGSPCFNRLFYAVDVDDDIWEDEVED :::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 QYFCWICMGSLSRANPYKHFNDPGSPCFNRLFYAVDVDDDIWEDEVED 310 320 330 340 >>CCDS4270.1 RNF14 gene_id:9604|Hs108|chr5 (474 aa) initn: 2468 init1: 2468 opt: 2468 Z-score: 2321.7 bits: 438.5 E(32554): 5.3e-123 Smith-Waterman score: 2468; 100.0% identity (100.0% similar) in 348 aa overlap (1-348:127-474) 10 20 30 pF1KB4 MQFLKEETLAYLNIVSPFELKIGSQKKVQR :::::::::::::::::::::::::::::: CCDS42 WLSPTQLSALCKHLDNLWEEHRGSVVLFAWMQFLKEETLAYLNIVSPFELKIGSQKKVQR 100 110 120 130 140 150 40 50 60 70 80 90 pF1KB4 RTAQASPNTELDFGGAAGSDVDQEEIVDERAVQDVESLSNLIQEILDFDQAQQIKCFNSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 RTAQASPNTELDFGGAAGSDVDQEEIVDERAVQDVESLSNLIQEILDFDQAQQIKCFNSK 160 170 180 190 200 210 100 110 120 130 140 150 pF1KB4 LFLCSICFCEKLGSECMYFLECRHVYCKACLKDYFEIQIRDGQVQCLNCPEPKCPSVATP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 LFLCSICFCEKLGSECMYFLECRHVYCKACLKDYFEIQIRDGQVQCLNCPEPKCPSVATP 220 230 240 250 260 270 160 170 180 190 200 210 pF1KB4 GQVKELVEAELFARYDRLLLQSSLDLMADVVYCPRPCCQLPVMQEPGCTMGICSSCNFAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 GQVKELVEAELFARYDRLLLQSSLDLMADVVYCPRPCCQLPVMQEPGCTMGICSSCNFAF 280 290 300 310 320 330 220 230 240 250 260 270 pF1KB4 CTLCRLTYHGVSPCKVTAEKLMDLRNEYLQADEANKRLLDQRYGKRVIQKALEEMESKEW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 CTLCRLTYHGVSPCKVTAEKLMDLRNEYLQADEANKRLLDQRYGKRVIQKALEEMESKEW 340 350 360 370 380 390 280 290 300 310 320 330 pF1KB4 LEKNSKSCPCCGTPIEKLDGCNKMTCTGCMQYFCWICMGSLSRANPYKHFNDPGSPCFNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 LEKNSKSCPCCGTPIEKLDGCNKMTCTGCMQYFCWICMGSLSRANPYKHFNDPGSPCFNR 400 410 420 430 440 450 340 pF1KB4 LFYAVDVDDDIWEDEVED :::::::::::::::::: CCDS42 LFYAVDVDDDIWEDEVED 460 470 >>CCDS47639.1 ANKIB1 gene_id:54467|Hs108|chr7 (1089 aa) initn: 418 init1: 186 opt: 336 Z-score: 320.4 bits: 69.4 E(32554): 1.6e-11 Smith-Waterman score: 341; 26.0% identity (51.5% similar) in 231 aa overlap (93-308:332-549) 70 80 90 100 110 120 pF1KB4 QDVESLSNLIQEILDFDQAQQIKCFNSKLFLCSICFCEKLGSECMYFLECRHVYCKACLK ::.::.: : . : : .:..: . CCDS47 LPSPRTPRTTRSSVTSPDEISLSPGDLDTSLCDICMCSISVFEDPVDMPCGHDFCRGCWE 310 320 330 340 350 360 130 140 150 160 170 180 pF1KB4 DYFEIQIRDGQVQCLNCPEPKCPSVATPGQVKELVEAELFARYDRLLLQSSLDLMADVVY ......:..:... . :: : ... .. .: :. :: .. ... .. . . CCDS47 SFLNLKIQEGEAHNIFCPAYDCFQLVPVDIIESVVSKEMDKRYLQFDIKAFVENNPAIKW 370 380 390 400 410 420 190 200 210 220 pF1KB4 CPRPCCQLPV-MQEPGCTMGICSSCNFA--------------FCTLCRLTYHGVSPCKVT :: : :. : . . : . . .. .: :: : : :: CCDS47 CPTPGCDRAVRLTKQGSNTSGSDTLSFPLLRAPAVDCGKGHLFCWECLGEAH--EPCDCQ 430 440 450 460 470 230 240 250 260 270 280 pF1KB4 AEKLMDLRNEYLQADEANKRLLDQRYGKRVIQKALEEMESKEWLEKNSKSCPCCGTPIEK . : ..:: : .. : ...: :. . :: ::: : : .::.: CCDS47 TWK------NWLQKITEMKP--EELVG---VSEAYEDAANCLWLLTNSKPCANCKSPIQK 480 490 500 510 520 290 300 310 320 330 340 pF1KB4 LDGCNKMTCTGCMQYFCWICMGSLSRANPYKHFNDPGSPCFNRLFYAVDVDDDIWEDEVE .:::.: :. : :::::. CCDS47 NEGCNHMQCAKCKYDFCWICLEEWKKHSSSTGGYYRCTRYEVIQHVEEQSKEMTVEAEKK 530 540 550 560 570 580 348 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 20:35:54 2016 done: Fri Nov 4 20:35:54 2016 Total Scan time: 2.230 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]