FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB4563, 910 aa 1>>>pF1KB4563 910 - 910 aa - 910 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.4976+/-0.000411; mu= 20.0860+/- 0.026 mean_var=71.3736+/-13.998, 0's: 0 Z-trim(111.5): 63 B-trim: 100 in 1/52 Lambda= 0.151812 statistics sampled from 19992 (20055) to 19992 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.598), E-opt: 0.2 (0.235), width: 16 Scan time: 11.920 The best scores are: opt bits E(85289) NP_055205 (OMIM: 602181) staphylococcal nuclease d ( 910) 5972 1318.0 0 XP_016867476 (OMIM: 602181) PREDICTED: staphylococ ( 607) 3889 861.6 0 XP_016871903 (OMIM: 605796) PREDICTED: tudor domai (1141) 219 58.0 3.1e-07 XP_016855618 (OMIM: 609501) PREDICTED: tudor and K ( 337) 199 53.3 2.3e-06 XP_016855617 (OMIM: 609501) PREDICTED: tudor and K ( 337) 199 53.3 2.3e-06 XP_016855619 (OMIM: 609501) PREDICTED: tudor and K ( 337) 199 53.3 2.3e-06 XP_005244913 (OMIM: 609501) PREDICTED: tudor and K ( 337) 199 53.3 2.3e-06 XP_005270036 (OMIM: 605796) PREDICTED: tudor domai (1113) 204 54.7 2.9e-06 XP_011538265 (OMIM: 605796) PREDICTED: tudor domai (1180) 204 54.7 3.1e-06 XP_005270035 (OMIM: 605796) PREDICTED: tudor domai (1189) 204 54.7 3.1e-06 XP_011538262 (OMIM: 605796) PREDICTED: tudor domai (1189) 204 54.7 3.1e-06 XP_011538263 (OMIM: 605796) PREDICTED: tudor domai (1189) 204 54.7 3.1e-06 XP_011538264 (OMIM: 605796) PREDICTED: tudor domai (1189) 204 54.7 3.1e-06 NP_942090 (OMIM: 605796) tudor domain-containing p (1189) 204 54.7 3.1e-06 XP_011538261 (OMIM: 605796) PREDICTED: tudor domai (1189) 204 54.7 3.1e-06 NP_001077433 (OMIM: 609501) tudor and KH domain-co ( 516) 199 53.4 3.3e-06 XP_016855615 (OMIM: 609501) PREDICTED: tudor and K ( 561) 199 53.4 3.5e-06 XP_016855614 (OMIM: 609501) PREDICTED: tudor and K ( 561) 199 53.4 3.5e-06 NP_001077432 (OMIM: 609501) tudor and KH domain-co ( 561) 199 53.4 3.5e-06 XP_016855616 (OMIM: 609501) PREDICTED: tudor and K ( 561) 199 53.4 3.5e-06 NP_006853 (OMIM: 609501) tudor and KH domain-conta ( 561) 199 53.4 3.5e-06 XP_016855611 (OMIM: 609501) PREDICTED: tudor and K ( 561) 199 53.4 3.5e-06 XP_016855612 (OMIM: 609501) PREDICTED: tudor and K ( 561) 199 53.4 3.5e-06 XP_016855613 (OMIM: 609501) PREDICTED: tudor and K ( 561) 199 53.4 3.5e-06 NP_001077434 (OMIM: 609501) tudor and KH domain-co ( 561) 199 53.4 3.5e-06 NP_001171922 (OMIM: 605793) RING finger protein 17 (1619) 194 52.6 1.8e-05 NP_112567 (OMIM: 605793) RING finger protein 17 is (1623) 194 52.6 1.8e-05 XP_011533462 (OMIM: 605793) PREDICTED: RING finger (1646) 194 52.6 1.9e-05 XP_011533461 (OMIM: 605793) PREDICTED: RING finger (1650) 194 52.6 1.9e-05 NP_001161831 (OMIM: 611200) tudor domain-containin (2066) 185 50.7 8.8e-05 NP_001010870 (OMIM: 611200) tudor domain-containin (2096) 185 50.7 8.9e-05 XP_016880680 (OMIM: 602449) PREDICTED: A-kinase an ( 903) 152 43.3 0.0066 XP_005257764 (OMIM: 602449) PREDICTED: A-kinase an ( 903) 152 43.3 0.0066 NP_001229832 (OMIM: 602449) A-kinase anchor protei ( 903) 152 43.3 0.0066 XP_016880679 (OMIM: 602449) PREDICTED: A-kinase an ( 903) 152 43.3 0.0066 XP_016880678 (OMIM: 602449) PREDICTED: A-kinase an ( 903) 152 43.3 0.0066 NP_001229831 (OMIM: 602449) A-kinase anchor protei ( 903) 152 43.3 0.0066 NP_003479 (OMIM: 602449) A-kinase anchor protein 1 ( 903) 152 43.3 0.0066 XP_005257766 (OMIM: 602449) PREDICTED: A-kinase an ( 903) 152 43.3 0.0066 XP_011533465 (OMIM: 605793) PREDICTED: RING finger (1261) 153 43.6 0.0075 XP_011533464 (OMIM: 605793) PREDICTED: RING finger (1498) 153 43.6 0.0087 XP_006719915 (OMIM: 605793) PREDICTED: RING finger (1531) 153 43.6 0.0088 XP_016876165 (OMIM: 605793) PREDICTED: RING finger (1611) 153 43.6 0.0092 XP_011533460 (OMIM: 605793) PREDICTED: RING finger (1657) 153 43.6 0.0094 XP_006719912 (OMIM: 605793) PREDICTED: RING finger (1672) 153 43.6 0.0095 XP_006719909 (OMIM: 605793) PREDICTED: RING finger (1692) 153 43.6 0.0096 XP_011533459 (OMIM: 605793) PREDICTED: RING finger (1695) 153 43.6 0.0096 XP_011533457 (OMIM: 605793) PREDICTED: RING finger (1699) 153 43.6 0.0096 XP_011533454 (OMIM: 605793) PREDICTED: RING finger (1699) 153 43.6 0.0096 XP_011533458 (OMIM: 605793) PREDICTED: RING finger (1699) 153 43.6 0.0096 >>NP_055205 (OMIM: 602181) staphylococcal nuclease domai (910 aa) initn: 5972 init1: 5972 opt: 5972 Z-score: 7062.1 bits: 1318.0 E(85289): 0 Smith-Waterman score: 5972; 99.9% identity (99.9% similar) in 910 aa overlap (1-910:1-910) 10 20 30 40 50 60 pF1KB4 MASSAQSGGSSGGPAVPTVQRGIIKMVLSGCAIIVRGQPRGGPPPERQINLSNIRAGNLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 MASSAQSGGSSGGPAVPTVQRGIIKMVLSGCAIIVRGQPRGGPPPERQINLSNIRAGNLA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 RRAAATQPDAKDTPDEPWAFPAREFLRKKLIGKEVCFTIENKTPQGREYGMIYLGKDTNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 RRAAATQPDAKDTPDEPWAFPAREFLRKKLIGKEVCFTIENKTPQGREYGMIYLGKDTNG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 ENIAESLVAEGLATRREGMRANNPEQNRLSECEEQAKAAKKGMWSEGNGSHTIRDLKYTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 ENIAESLVAEGLATRREGMRANNPEQNRLSECEEQAKAAKKGMWSEGNGSHTIRDLKYTI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 ENPRHFVDSHHQKPVNAIIEHVRDGSVVRALLLPDYYLVTVMLSGIKCPTFRREADGSET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 ENPRHFVDSHHQKPVNAIIEHVRDGSVVRALLLPDYYLVTVMLSGIKCPTFRREADGSET 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 PEPFAAEAKFFTESRLLQRDVQIILESCHNQNILGTILHPNGNITELLLKEGFARCVDWS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 PEPFAAEAKFFTESRLLQRDVQIILESCHNQNILGTILHPNGNITELLLKEGFARCVDWS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 IAVYTRGAEKLRAAERVAKERRLRIWRDYVAPTANLDQKDKQFVAKVMQVLNADAIVVKL :::::::::::::::: ::::::::::::::::::::::::::::::::::::::::::: NP_055 IAVYTRGAEKLRAAERFAKERRLRIWRDYVAPTANLDQKDKQFVAKVMQVLNADAIVVKL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB4 NSGDYKTIHLSSIRPPRLEGENTQDKNKKLRPLYDIPYMFEAREFLRKKLIGKKVNVTVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 NSGDYKTIHLSSIRPPRLEGENTQDKNKKLRPLYDIPYMFEAREFLRKKLIGKKVNVTVD 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB4 YIRPASPATETVPAFSERTCATVTIGGINIAEALVSKGLATVIRYRQDDDQRSSHYDELL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 YIRPASPATETVPAFSERTCATVTIGGINIAEALVSKGLATVIRYRQDDDQRSSHYDELL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB4 AAEARAIKNGKGLHSKKEVPIHRVADISGDTQKAKQFLPFLQRAGRSEAVVEYVFSGSRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 AAEARAIKNGKGLHSKKEVPIHRVADISGDTQKAKQFLPFLQRAGRSEAVVEYVFSGSRL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB4 KLYLPKETCLITFLLAGIECPRGARNLPGLVQEGEPFSEEATLFTKELVLQREVEVEVES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 KLYLPKETCLITFLLAGIECPRGARNLPGLVQEGEPFSEEATLFTKELVLQREVEVEVES 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB4 MDKAGNFIGWLHIDGANLSVLLVEHALSKVHFTAERSSYYKSLLSAEEAAKQKKEKVWAH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 MDKAGNFIGWLHIDGANLSVLLVEHALSKVHFTAERSSYYKSLLSAEEAAKQKKEKVWAH 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB4 YEEQPVEEVMPVLEEKERSASYKPVFVTEITDDLHFYVQDVETGTQLEKLMENMRNDIAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 YEEQPVEEVMPVLEEKERSASYKPVFVTEITDDLHFYVQDVETGTQLEKLMENMRNDIAS 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB4 HPPVEGSYAPRRGEFCIAKFVDGEWYRARVEKVESPAKIHVFYIDYGNREVLPSTRLGTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 HPPVEGSYAPRRGEFCIAKFVDGEWYRARVEKVESPAKIHVFYIDYGNREVLPSTRLGTL 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB4 SPAFSTRVLPAQATEYAFAFIQVPQDDDARTDAVDSVVRDIQNTQCLLNVEHLSAGCPHV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 SPAFSTRVLPAQATEYAFAFIQVPQDDDARTDAVDSVVRDIQNTQCLLNVEHLSAGCPHV 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB4 TLQFADSKGDVGLGLVKEGLVMVEVRKEKQFQKVITEYLNAQESAKSARLNLWRYGDFRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 TLQFADSKGDVGLGLVKEGLVMVEVRKEKQFQKVITEYLNAQESAKSARLNLWRYGDFRA 850 860 870 880 890 900 910 pF1KB4 DDADEFGYSR :::::::::: NP_055 DDADEFGYSR 910 >>XP_016867476 (OMIM: 602181) PREDICTED: staphylococcal (607 aa) initn: 3889 init1: 3889 opt: 3889 Z-score: 4599.1 bits: 861.6 E(85289): 0 Smith-Waterman score: 3889; 99.8% identity (99.8% similar) in 593 aa overlap (1-593:1-593) 10 20 30 40 50 60 pF1KB4 MASSAQSGGSSGGPAVPTVQRGIIKMVLSGCAIIVRGQPRGGPPPERQINLSNIRAGNLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MASSAQSGGSSGGPAVPTVQRGIIKMVLSGCAIIVRGQPRGGPPPERQINLSNIRAGNLA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 RRAAATQPDAKDTPDEPWAFPAREFLRKKLIGKEVCFTIENKTPQGREYGMIYLGKDTNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RRAAATQPDAKDTPDEPWAFPAREFLRKKLIGKEVCFTIENKTPQGREYGMIYLGKDTNG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 ENIAESLVAEGLATRREGMRANNPEQNRLSECEEQAKAAKKGMWSEGNGSHTIRDLKYTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ENIAESLVAEGLATRREGMRANNPEQNRLSECEEQAKAAKKGMWSEGNGSHTIRDLKYTI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 ENPRHFVDSHHQKPVNAIIEHVRDGSVVRALLLPDYYLVTVMLSGIKCPTFRREADGSET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ENPRHFVDSHHQKPVNAIIEHVRDGSVVRALLLPDYYLVTVMLSGIKCPTFRREADGSET 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 PEPFAAEAKFFTESRLLQRDVQIILESCHNQNILGTILHPNGNITELLLKEGFARCVDWS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PEPFAAEAKFFTESRLLQRDVQIILESCHNQNILGTILHPNGNITELLLKEGFARCVDWS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 IAVYTRGAEKLRAAERVAKERRLRIWRDYVAPTANLDQKDKQFVAKVMQVLNADAIVVKL :::::::::::::::: ::::::::::::::::::::::::::::::::::::::::::: XP_016 IAVYTRGAEKLRAAERFAKERRLRIWRDYVAPTANLDQKDKQFVAKVMQVLNADAIVVKL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB4 NSGDYKTIHLSSIRPPRLEGENTQDKNKKLRPLYDIPYMFEAREFLRKKLIGKKVNVTVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NSGDYKTIHLSSIRPPRLEGENTQDKNKKLRPLYDIPYMFEAREFLRKKLIGKKVNVTVD 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB4 YIRPASPATETVPAFSERTCATVTIGGINIAEALVSKGLATVIRYRQDDDQRSSHYDELL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YIRPASPATETVPAFSERTCATVTIGGINIAEALVSKGLATVIRYRQDDDQRSSHYDELL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB4 AAEARAIKNGKGLHSKKEVPIHRVADISGDTQKAKQFLPFLQRAGRSEAVVEYVFSGSRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AAEARAIKNGKGLHSKKEVPIHRVADISGDTQKAKQFLPFLQRAGRSEAVVEYVFSGSRL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB4 KLYLPKETCLITFLLAGIECPRGARNLPGLVQEGEPFSEEATLFTKELVLQREVEVEVES ::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KLYLPKETCLITFLLAGIECPRGARNLPGLVQEGEPFSEEATLFTKELVLQRECLPDNSL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB4 MDKAGNFIGWLHIDGANLSVLLVEHALSKVHFTAERSSYYKSLLSAEEAAKQKKEKVWAH XP_016 IIHLKYK >>XP_016871903 (OMIM: 605796) PREDICTED: tudor domain-co (1141 aa) initn: 311 init1: 114 opt: 219 Z-score: 250.9 bits: 58.0 E(85289): 3.1e-07 Smith-Waterman score: 219; 22.7% identity (53.5% similar) in 353 aa overlap (482-823:247-585) 460 470 480 490 500 pF1KB4 EALVSKGLATVIRYRQDDDQRSSHYDELLAAEARAIKNGKGLHSKKEVPIH-RVADIS-- :: ... ..:. :: . :. :.... XP_016 ENKSSIETKDVEVNNKSDCPLGVTKEIAIWAERIMFSDLRSLQLKKTMEIKGTVTEFKHP 220 230 240 250 260 270 510 520 530 540 550 560 pF1KB4 GDTQKAKQFLPFLQRAGRSEAVVEYVFSGSRLKLYLP--KETCLITFLL-AGIECPRGAR :: :. .. : .. .... . : :.: :.:. . . .:.: : XP_016 GDFYVQLYSSEVLEYMNQLSASLKETYANVHEKDYIPVKGEVCIAKYTVDQAIKC-FVAN 280 290 300 310 320 330 570 580 590 600 610 620 pF1KB4 NLPGLVQEGEPFSEEATLFTKELVLQREVEVEVESMDKAGNFIGWLHIDGANLSVLLVEH .:. ::. .: . :: :.... ... .. . .... : : :..: XP_016 VIPA---EGN-WSSDCIKATKPLLMEQYCSIKIVDILEEEVVTFAVEVELPN-SGKLLDH 340 350 360 370 380 390 630 640 650 660 670 680 pF1KB4 ALSKVHFTAERSSYYKSLLSAEEAAKQKKEKVWAHYEEQPV----EEVMPVLEEKERSAS .: .. . . :. .. :.: .. : : :. . ...: . . . XP_016 VLIEMGYGLKPSGQDSK---KENADQSDPEDVGKMTTENNIVVDKSDLIPKVLTLNVGDE 400 410 420 430 440 690 700 710 720 730 740 pF1KB4 YKPVFVTEITDDLHFYVQDVETGTQLEKLMENMRNDIASHPPVEGSYAPRRGEFCIAKFV . : :..: :. :....: .: .:. .. . . :: .... : :..: :.: XP_016 FCGV-VAHIQTPEDFFCQQLQSGRKLAELQASLSKYCDQLPP-RSDFYPAIGDICCAQFS 450 460 470 480 490 500 750 760 770 780 790 800 pF1KB4 -DGEWYRARVEKVESPAKIHVFYIDYGNREVLPSTRLGTLSPAFSTRVLPAQATEYAFAF : .:::: : : .. : :.:::: :.: :: . : . :: :: . ..: XP_016 EDDQWYRASVLAYASEESVLVGYVDYGNFEILSLMRLCPIIPKLLE--LPMQAIKCVLAG 510 520 530 540 550 560 810 820 830 840 850 860 pF1KB4 IQVPQDDDARTDAVDSVVRDIQNTQCLLNVEHLSAGCPHVTLQFADSKGDVGLGLVKEGL .. :. .:. . . .:: XP_016 VK-PSLGIWTPEAICLMKKLVQNKIITVKVVDKLENSSLVELIDKSETPHVSVSKVLLDA 570 580 590 600 610 620 >>XP_016855618 (OMIM: 609501) PREDICTED: tudor and KH do (337 aa) initn: 56 init1: 56 opt: 199 Z-score: 235.2 bits: 53.3 E(85289): 2.3e-06 Smith-Waterman score: 199; 24.4% identity (55.6% similar) in 266 aa overlap (643-891:40-297) 620 630 640 650 660 670 pF1KB4 IDGANLSVLLVEHALSKVHFTAERSSYYKSLLSAEEAAKQKKEKVWAHYEEQPVEEVMPV ..: : . .. .. . . : : . : ::. XP_016 PALWKNTSSSMEPTAPLVTPPPKGGGDMAVVVSKEGSWEKPSDDSFQKSEAQAIPE-MPM 10 20 30 40 50 60 680 690 700 710 720 pF1KB4 LEEKERSAS-----YKPVFVTEITDDLHFYVQDVETGT-QLEKLMENMRNDIASHPPVEG .: . : : :.:. ::..: : . . ::.::...: . . : . XP_016 FEIPSPDFSFHADEYLEVYVSASEHPNHFWIQIVGSRSLQLDKLVNEMTQHYENSVPEDL 70 80 90 100 110 120 730 740 750 760 770 780 pF1KB4 SYAPRRGEFCIAKF-VDGEWYRARVEKVESPAKIHVFYIDYGNREVLPSTRLGTLSPAFS . . :.. : . ..: :::::: . ... ....:.:. : : .: : XP_016 TV--HVGDIVAAPLPTNGSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFL 130 140 150 160 170 180 790 800 810 820 830 pF1KB4 TRVLPAQATEYAFAFIQVPQDDDARTDAVDSVVRDIQNTQCLLNVEHLSAGC-------P . :: :: : ..: : .:. :. . .:.: : . .. : ..:. : XP_016 S--LPFQAIECSLARI-APSGDQWEEEALDEFDRLTHCADWKPLVAKISSYVQTGISTWP 190 200 210 220 230 240 840 850 860 870 880 890 pF1KB4 HVTLQFADSKG---DVGLGLVKEGLVMVEVRKEKQFQKVITEYLNAQESAKSARLNLWRY .. : . :.: :.:: ::..: . .:. .. . .... ..:. . . .: :. XP_016 KIYL-YDTSNGKKLDIGLELVHKGYA-IELPEDIEENRAVPDMLKDMATETDASLSTLLT 250 260 270 280 290 300 900 910 pF1KB4 GDFRADDADEFGYSR XP_016 ETKKSSGEITHTLSCLSLSEAASMSGDDNLEDDYLL 310 320 330 >>XP_016855617 (OMIM: 609501) PREDICTED: tudor and KH do (337 aa) initn: 56 init1: 56 opt: 199 Z-score: 235.2 bits: 53.3 E(85289): 2.3e-06 Smith-Waterman score: 199; 24.4% identity (55.6% similar) in 266 aa overlap (643-891:40-297) 620 630 640 650 660 670 pF1KB4 IDGANLSVLLVEHALSKVHFTAERSSYYKSLLSAEEAAKQKKEKVWAHYEEQPVEEVMPV ..: : . .. .. . . : : . : ::. XP_016 PALWKNTSSSMEPTAPLVTPPPKGGGDMAVVVSKEGSWEKPSDDSFQKSEAQAIPE-MPM 10 20 30 40 50 60 680 690 700 710 720 pF1KB4 LEEKERSAS-----YKPVFVTEITDDLHFYVQDVETGT-QLEKLMENMRNDIASHPPVEG .: . : : :.:. ::..: : . . ::.::...: . . : . XP_016 FEIPSPDFSFHADEYLEVYVSASEHPNHFWIQIVGSRSLQLDKLVNEMTQHYENSVPEDL 70 80 90 100 110 120 730 740 750 760 770 780 pF1KB4 SYAPRRGEFCIAKF-VDGEWYRARVEKVESPAKIHVFYIDYGNREVLPSTRLGTLSPAFS . . :.. : . ..: :::::: . ... ....:.:. : : .: : XP_016 TV--HVGDIVAAPLPTNGSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFL 130 140 150 160 170 180 790 800 810 820 830 pF1KB4 TRVLPAQATEYAFAFIQVPQDDDARTDAVDSVVRDIQNTQCLLNVEHLSAGC-------P . :: :: : ..: : .:. :. . .:.: : . .. : ..:. : XP_016 S--LPFQAIECSLARI-APSGDQWEEEALDEFDRLTHCADWKPLVAKISSYVQTGISTWP 190 200 210 220 230 240 840 850 860 870 880 890 pF1KB4 HVTLQFADSKG---DVGLGLVKEGLVMVEVRKEKQFQKVITEYLNAQESAKSARLNLWRY .. : . :.: :.:: ::..: . .:. .. . .... ..:. . . .: :. XP_016 KIYL-YDTSNGKKLDIGLELVHKGYA-IELPEDIEENRAVPDMLKDMATETDASLSTLLT 250 260 270 280 290 300 900 910 pF1KB4 GDFRADDADEFGYSR XP_016 ETKKSSGEITHTLSCLSLSEAASMSGDDNLEDDYLL 310 320 330 >>XP_016855619 (OMIM: 609501) PREDICTED: tudor and KH do (337 aa) initn: 56 init1: 56 opt: 199 Z-score: 235.2 bits: 53.3 E(85289): 2.3e-06 Smith-Waterman score: 199; 24.4% identity (55.6% similar) in 266 aa overlap (643-891:40-297) 620 630 640 650 660 670 pF1KB4 IDGANLSVLLVEHALSKVHFTAERSSYYKSLLSAEEAAKQKKEKVWAHYEEQPVEEVMPV ..: : . .. .. . . : : . : ::. XP_016 PALWKNTSSSMEPTAPLVTPPPKGGGDMAVVVSKEGSWEKPSDDSFQKSEAQAIPE-MPM 10 20 30 40 50 60 680 690 700 710 720 pF1KB4 LEEKERSAS-----YKPVFVTEITDDLHFYVQDVETGT-QLEKLMENMRNDIASHPPVEG .: . : : :.:. ::..: : . . ::.::...: . . : . XP_016 FEIPSPDFSFHADEYLEVYVSASEHPNHFWIQIVGSRSLQLDKLVNEMTQHYENSVPEDL 70 80 90 100 110 120 730 740 750 760 770 780 pF1KB4 SYAPRRGEFCIAKF-VDGEWYRARVEKVESPAKIHVFYIDYGNREVLPSTRLGTLSPAFS . . :.. : . ..: :::::: . ... ....:.:. : : .: : XP_016 TV--HVGDIVAAPLPTNGSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFL 130 140 150 160 170 180 790 800 810 820 830 pF1KB4 TRVLPAQATEYAFAFIQVPQDDDARTDAVDSVVRDIQNTQCLLNVEHLSAGC-------P . :: :: : ..: : .:. :. . .:.: : . .. : ..:. : XP_016 S--LPFQAIECSLARI-APSGDQWEEEALDEFDRLTHCADWKPLVAKISSYVQTGISTWP 190 200 210 220 230 240 840 850 860 870 880 890 pF1KB4 HVTLQFADSKG---DVGLGLVKEGLVMVEVRKEKQFQKVITEYLNAQESAKSARLNLWRY .. : . :.: :.:: ::..: . .:. .. . .... ..:. . . .: :. XP_016 KIYL-YDTSNGKKLDIGLELVHKGYA-IELPEDIEENRAVPDMLKDMATETDASLSTLLT 250 260 270 280 290 300 900 910 pF1KB4 GDFRADDADEFGYSR XP_016 ETKKSSGEITHTLSCLSLSEAASMSGDDNLEDDYLL 310 320 330 >>XP_005244913 (OMIM: 609501) PREDICTED: tudor and KH do (337 aa) initn: 56 init1: 56 opt: 199 Z-score: 235.2 bits: 53.3 E(85289): 2.3e-06 Smith-Waterman score: 199; 24.4% identity (55.6% similar) in 266 aa overlap (643-891:40-297) 620 630 640 650 660 670 pF1KB4 IDGANLSVLLVEHALSKVHFTAERSSYYKSLLSAEEAAKQKKEKVWAHYEEQPVEEVMPV ..: : . .. .. . . : : . : ::. XP_005 PALWKNTSSSMEPTAPLVTPPPKGGGDMAVVVSKEGSWEKPSDDSFQKSEAQAIPE-MPM 10 20 30 40 50 60 680 690 700 710 720 pF1KB4 LEEKERSAS-----YKPVFVTEITDDLHFYVQDVETGT-QLEKLMENMRNDIASHPPVEG .: . : : :.:. ::..: : . . ::.::...: . . : . XP_005 FEIPSPDFSFHADEYLEVYVSASEHPNHFWIQIVGSRSLQLDKLVNEMTQHYENSVPEDL 70 80 90 100 110 120 730 740 750 760 770 780 pF1KB4 SYAPRRGEFCIAKF-VDGEWYRARVEKVESPAKIHVFYIDYGNREVLPSTRLGTLSPAFS . . :.. : . ..: :::::: . ... ....:.:. : : .: : XP_005 TV--HVGDIVAAPLPTNGSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFL 130 140 150 160 170 180 790 800 810 820 830 pF1KB4 TRVLPAQATEYAFAFIQVPQDDDARTDAVDSVVRDIQNTQCLLNVEHLSAGC-------P . :: :: : ..: : .:. :. . .:.: : . .. : ..:. : XP_005 S--LPFQAIECSLARI-APSGDQWEEEALDEFDRLTHCADWKPLVAKISSYVQTGISTWP 190 200 210 220 230 240 840 850 860 870 880 890 pF1KB4 HVTLQFADSKG---DVGLGLVKEGLVMVEVRKEKQFQKVITEYLNAQESAKSARLNLWRY .. : . :.: :.:: ::..: . .:. .. . .... ..:. . . .: :. XP_005 KIYL-YDTSNGKKLDIGLELVHKGYA-IELPEDIEENRAVPDMLKDMATETDASLSTLLT 250 260 270 280 290 300 900 910 pF1KB4 GDFRADDADEFGYSR XP_005 ETKKSSGEITHTLSCLSLSEAASMSGDDNLEDDYLL 310 320 330 >>XP_005270036 (OMIM: 605796) PREDICTED: tudor domain-co (1113 aa) initn: 338 init1: 114 opt: 204 Z-score: 233.3 bits: 54.7 E(85289): 2.9e-06 Smith-Waterman score: 211; 30.2% identity (60.4% similar) in 149 aa overlap (687-830:270-412) 660 670 680 690 700 710 pF1KB4 VWAHYEEQPVEEVMPVLEEKERSASYKPVFVTEITDDLHFYVQ--DVETGTQLEKLMENM :::. :::: . :. ...: .. XP_005 TKEIAIWAERIMFSDLRSLQLKKTMEIKGTVTEFKHPGDFYVQLYSSEVLEYMNQLSASL 240 250 260 270 280 290 720 730 740 750 760 770 pF1KB4 RNDIAS-HPPVEGSYAPRRGEFCIAKF-VDGEWYRARVEKVE-SPAKIHVFYIDYGNREV .. :. : : .: : .:: ::::. :: : :: ...:. . : ::.::::::.:. XP_005 KETYANVH---EKDYIPVKGEVCIAKYTVDQTWNRAIIQNVDVQQKKAHVLYIDYGNEEI 300 310 320 330 340 350 780 790 800 810 820 830 pF1KB4 LPSTRLGTLSPAFSTRVLPAQATEYAFAFIQVPQDDDARTDAVDSVVRDIQNTQCLLNVE .: .:. :. .. ..: : . :. .: . . .: . .. ... : ... XP_005 IPLNRIYHLNRNID--LFPPCAIK-CFVANVIPAEGNWSSDCIKATKPLLMEQYCSIKIV 360 370 380 390 400 410 840 850 860 870 880 890 pF1KB4 HLSAGCPHVTLQFADSKGDVGLGLVKEGLVMVEVRKEKQFQKVITEYLNAQESAKSARLN XP_005 DILEEEVVTFAVEVELPNSGKLLDHVLIEMGYGLKPSGQDSKKENADQSDPEDVGKMTTE 420 430 440 450 460 470 >-- initn: 311 init1: 114 opt: 203 Z-score: 232.1 bits: 54.5 E(85289): 3.4e-06 Smith-Waterman score: 203; 29.7% identity (58.0% similar) in 138 aa overlap (687-823:500-633) 660 670 680 690 700 710 pF1KB4 VWAHYEEQPVEEVMPVLEEKERSASYKPVFVTEITDDLHFYVQDVETGTQLEKLMENMRN :..: :. :....: .: .:. .. . XP_005 MTTENNIVVDKSDLIPKVLTLNVGDEFCGVVAHIQTPEDFFCQQLQSGRKLAELQASLSK 470 480 490 500 510 520 720 730 740 750 760 770 pF1KB4 DIASHPPVEGSYAPRRGEFCIAKFV-DGEWYRARVEKVESPAKIHVFYIDYGNREVLPST . :: .... : :..: :.: : .:::: : : .. : :.:::: :.: XP_005 YCDQLPP-RSDFYPAIGDICCAQFSEDDQWYRASVLAYASEESVLVGYVDYGNFEILSLM 530 540 550 560 570 580 780 790 800 810 820 830 pF1KB4 RLGTLSPAFSTRVLPAQATEYAFAFIQVPQDDDARTDAVDSVVRDIQNTQCLLNVEHLSA :: . : . :: :: . ..: .. :. .:. . . .:: XP_005 RLCPIIPKLLE--LPMQAIKCVLAGVK-PSLGIWTPEAICLMKKLVQNKIITVKVVDKLE 590 600 610 620 630 640 840 850 860 870 880 890 pF1KB4 GCPHVTLQFADSKGDVGLGLVKEGLVMVEVRKEKQFQKVITEYLNAQESAKSARLNLWRY XP_005 NSSLVELIDKSETPHVSVSKVLLDAGFAVGEQSMVTDKPSDVKETSVPLGVEGKVNPLEW 650 660 670 680 690 700 >>XP_011538265 (OMIM: 605796) PREDICTED: tudor domain-co (1180 aa) initn: 338 init1: 114 opt: 204 Z-score: 233.0 bits: 54.7 E(85289): 3.1e-06 Smith-Waterman score: 211; 30.2% identity (60.4% similar) in 149 aa overlap (687-830:270-412) 660 670 680 690 700 710 pF1KB4 VWAHYEEQPVEEVMPVLEEKERSASYKPVFVTEITDDLHFYVQ--DVETGTQLEKLMENM :::. :::: . :. ...: .. XP_011 TKEIAIWAERIMFSDLRSLQLKKTMEIKGTVTEFKHPGDFYVQLYSSEVLEYMNQLSASL 240 250 260 270 280 290 720 730 740 750 760 770 pF1KB4 RNDIAS-HPPVEGSYAPRRGEFCIAKF-VDGEWYRARVEKVE-SPAKIHVFYIDYGNREV .. :. : : .: : .:: ::::. :: : :: ...:. . : ::.::::::.:. XP_011 KETYANVH---EKDYIPVKGEVCIAKYTVDQTWNRAIIQNVDVQQKKAHVLYIDYGNEEI 300 310 320 330 340 350 780 790 800 810 820 830 pF1KB4 LPSTRLGTLSPAFSTRVLPAQATEYAFAFIQVPQDDDARTDAVDSVVRDIQNTQCLLNVE .: .:. :. .. ..: : . :. .: . . .: . .. ... : ... XP_011 IPLNRIYHLNRNID--LFPPCAIK-CFVANVIPAEGNWSSDCIKATKPLLMEQYCSIKIV 360 370 380 390 400 410 840 850 860 870 880 890 pF1KB4 HLSAGCPHVTLQFADSKGDVGLGLVKEGLVMVEVRKEKQFQKVITEYLNAQESAKSARLN XP_011 DILEEEVVTFAVEVELPNSGKLLDHVLIEMGYGLKPSGQDSKKENADQSDPEDVGKMTTE 420 430 440 450 460 470 >-- initn: 323 init1: 114 opt: 203 Z-score: 231.8 bits: 54.5 E(85289): 3.6e-06 Smith-Waterman score: 203; 29.7% identity (58.0% similar) in 138 aa overlap (687-823:500-633) 660 670 680 690 700 710 pF1KB4 VWAHYEEQPVEEVMPVLEEKERSASYKPVFVTEITDDLHFYVQDVETGTQLEKLMENMRN :..: :. :....: .: .:. .. . XP_011 MTTENNIVVDKSDLIPKVLTLNVGDEFCGVVAHIQTPEDFFCQQLQSGRKLAELQASLSK 470 480 490 500 510 520 720 730 740 750 760 770 pF1KB4 DIASHPPVEGSYAPRRGEFCIAKFV-DGEWYRARVEKVESPAKIHVFYIDYGNREVLPST . :: .... : :..: :.: : .:::: : : .. : :.:::: :.: XP_011 YCDQLPP-RSDFYPAIGDICCAQFSEDDQWYRASVLAYASEESVLVGYVDYGNFEILSLM 530 540 550 560 570 580 780 790 800 810 820 830 pF1KB4 RLGTLSPAFSTRVLPAQATEYAFAFIQVPQDDDARTDAVDSVVRDIQNTQCLLNVEHLSA :: . : . :: :: . ..: .. :. .:. . . .:: XP_011 RLCPIIPKLLE--LPMQAIKCVLAGVK-PSLGIWTPEAICLMKKLVQNKIITVKVVDKLE 590 600 610 620 630 640 840 850 860 870 880 890 pF1KB4 GCPHVTLQFADSKGDVGLGLVKEGLVMVEVRKEKQFQKVITEYLNAQESAKSARLNLWRY XP_011 NSSLVELIDKSETPHVSVSKVLLDAGFAVGEQSMVTDKPSDVKETSVPLGVEGKVNPLEW 650 660 670 680 690 700 >>XP_005270035 (OMIM: 605796) PREDICTED: tudor domain-co (1189 aa) initn: 338 init1: 114 opt: 204 Z-score: 232.9 bits: 54.7 E(85289): 3.1e-06 Smith-Waterman score: 211; 30.2% identity (60.4% similar) in 149 aa overlap (687-830:270-412) 660 670 680 690 700 710 pF1KB4 VWAHYEEQPVEEVMPVLEEKERSASYKPVFVTEITDDLHFYVQ--DVETGTQLEKLMENM :::. :::: . :. ...: .. XP_005 TKEIAIWAERIMFSDLRSLQLKKTMEIKGTVTEFKHPGDFYVQLYSSEVLEYMNQLSASL 240 250 260 270 280 290 720 730 740 750 760 770 pF1KB4 RNDIAS-HPPVEGSYAPRRGEFCIAKF-VDGEWYRARVEKVE-SPAKIHVFYIDYGNREV .. :. : : .: : .:: ::::. :: : :: ...:. . : ::.::::::.:. XP_005 KETYANVH---EKDYIPVKGEVCIAKYTVDQTWNRAIIQNVDVQQKKAHVLYIDYGNEEI 300 310 320 330 340 350 780 790 800 810 820 830 pF1KB4 LPSTRLGTLSPAFSTRVLPAQATEYAFAFIQVPQDDDARTDAVDSVVRDIQNTQCLLNVE .: .:. :. .. ..: : . :. .: . . .: . .. ... : ... XP_005 IPLNRIYHLNRNID--LFPPCAIK-CFVANVIPAEGNWSSDCIKATKPLLMEQYCSIKIV 360 370 380 390 400 410 840 850 860 870 880 890 pF1KB4 HLSAGCPHVTLQFADSKGDVGLGLVKEGLVMVEVRKEKQFQKVITEYLNAQESAKSARLN XP_005 DILEEEVVTFAVEVELPNSGKLLDHVLIEMGYGLKPSGQDSKKENADQSDPEDVGKMTTE 420 430 440 450 460 470 >-- initn: 323 init1: 114 opt: 203 Z-score: 231.7 bits: 54.5 E(85289): 3.6e-06 Smith-Waterman score: 203; 29.7% identity (58.0% similar) in 138 aa overlap (687-823:500-633) 660 670 680 690 700 710 pF1KB4 VWAHYEEQPVEEVMPVLEEKERSASYKPVFVTEITDDLHFYVQDVETGTQLEKLMENMRN :..: :. :....: .: .:. .. . XP_005 MTTENNIVVDKSDLIPKVLTLNVGDEFCGVVAHIQTPEDFFCQQLQSGRKLAELQASLSK 470 480 490 500 510 520 720 730 740 750 760 770 pF1KB4 DIASHPPVEGSYAPRRGEFCIAKFV-DGEWYRARVEKVESPAKIHVFYIDYGNREVLPST . :: .... : :..: :.: : .:::: : : .. : :.:::: :.: XP_005 YCDQLPP-RSDFYPAIGDICCAQFSEDDQWYRASVLAYASEESVLVGYVDYGNFEILSLM 530 540 550 560 570 580 780 790 800 810 820 830 pF1KB4 RLGTLSPAFSTRVLPAQATEYAFAFIQVPQDDDARTDAVDSVVRDIQNTQCLLNVEHLSA :: . : . :: :: . ..: .. :. .:. . . .:: XP_005 RLCPIIPKLLE--LPMQAIKCVLAGVK-PSLGIWTPEAICLMKKLVQNKIITVKVVDKLE 590 600 610 620 630 640 840 850 860 870 880 890 pF1KB4 GCPHVTLQFADSKGDVGLGLVKEGLVMVEVRKEKQFQKVITEYLNAQESAKSARLNLWRY XP_005 NSSLVELIDKSETPHVSVSKVLLDAGFAVGEQSMVTDKPSDVKETSVPLGVEGKVNPLEW 650 660 670 680 690 700 910 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 15:08:16 2016 done: Thu Nov 3 15:08:18 2016 Total Scan time: 11.920 Total Display time: 0.150 Function used was FASTA [36.3.4 Apr, 2011]