FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB4568, 370 aa 1>>>pF1KB4568 370 - 370 aa - 370 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.7501+/-0.000813; mu= 14.5423+/- 0.049 mean_var=73.1658+/-14.302, 0's: 0 Z-trim(108.3): 20 B-trim: 0 in 0/50 Lambda= 0.149941 statistics sampled from 10080 (10095) to 10080 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.69), E-opt: 0.2 (0.31), width: 16 Scan time: 2.840 The best scores are: opt bits E(32554) CCDS2017.2 STARD7 gene_id:56910|Hs108|chr2 ( 370) 2497 549.2 2.1e-156 CCDS11588.1 PCTP gene_id:58488|Hs108|chr17 ( 214) 377 90.5 1.4e-18 CCDS82165.1 PCTP gene_id:58488|Hs108|chr17 ( 203) 346 83.8 1.4e-16 CCDS82166.1 PCTP gene_id:58488|Hs108|chr17 ( 219) 339 82.3 4.4e-16 CCDS45741.1 PCTP gene_id:58488|Hs108|chr17 ( 142) 292 72.1 3.5e-13 >>CCDS2017.2 STARD7 gene_id:56910|Hs108|chr2 (370 aa) initn: 2497 init1: 2497 opt: 2497 Z-score: 2921.6 bits: 549.2 E(32554): 2.1e-156 Smith-Waterman score: 2497; 100.0% identity (100.0% similar) in 370 aa overlap (1-370:1-370) 10 20 30 40 50 60 pF1KB4 MLPRRLLAAWLAGTRGGGLLALLANQCRFVTGLRVRRAQQIAQLYGRLYSESSRRVLLGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS20 MLPRRLLAAWLAGTRGGGLLALLANQCRFVTGLRVRRAQQIAQLYGRLYSESSRRVLLGR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 LWRRLHGRPGHASALMAALAGVFVWDEERIQEEELQRSINEMKRLEEMSNMFQSSGVQHH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS20 LWRRLHGRPGHASALMAALAGVFVWDEERIQEEELQRSINEMKRLEEMSNMFQSSGVQHH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 PPEPKAQTEGNEDSEGKEQRWEMVMDKKHFKLWRRPITGTHLYQYRVFGTYTDVTPRQFF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS20 PPEPKAQTEGNEDSEGKEQRWEMVMDKKHFKLWRRPITGTHLYQYRVFGTYTDVTPRQFF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 NVQLDTEYRKKWDALVIKLEVIERDVVSGSEVLHWVTHFPYPMYSRDYVYVRRYSVDQEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS20 NVQLDTEYRKKWDALVIKLEVIERDVVSGSEVLHWVTHFPYPMYSRDYVYVRRYSVDQEN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 NMMVLVSRAVEHPSVPESPEFVRVRSYESQMVIRPHKSFDENGFDYLLTYSDNPQTVFPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS20 NMMVLVSRAVEHPSVPESPEFVRVRSYESQMVIRPHKSFDENGFDYLLTYSDNPQTVFPR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 YCVSWMVSSGMPDFLEKLHMATLKAKNMEIKVKDYISAKPLEMSSEAKATSQSSERKNEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS20 YCVSWMVSSGMPDFLEKLHMATLKAKNMEIKVKDYISAKPLEMSSEAKATSQSSERKNEG 310 320 330 340 350 360 370 pF1KB4 SCGPARIEYA :::::::::: CCDS20 SCGPARIEYA 370 >>CCDS11588.1 PCTP gene_id:58488|Hs108|chr17 (214 aa) initn: 328 init1: 131 opt: 377 Z-score: 446.8 bits: 90.5 E(32554): 1.4e-18 Smith-Waterman score: 377; 30.6% identity (68.9% similar) in 183 aa overlap (141-321:30-206) 120 130 140 150 160 170 pF1KB4 MFQSSGVQHHPPEPKAQTEGNEDSEGKEQRWEMVMDKKHFKLWRRPITGTHLYQYRVFGT :..... . ....: : ::.:.:::. CCDS11 MELAAGSFSEEQFWEACAELQQPALAGADWQLLVETSGISIYRLLDKKTGLYEYKVFGV 10 20 30 40 50 180 190 200 210 220 230 pF1KB4 YTDVTPRQFFNVQLDTEYRKKWDALVIKLEVIERDVVSGSEVLHWVTHFPYPMYSRDYVY : .: . .. .:..:::.:: : :. :.. .: :..: ...:.:: .::::: CCDS11 LEDCSPTLLADIYMDSDYRKQWDQYV--KELYEQEC-NGETVVYWEVKYPFPMSNRDYVY 60 70 80 90 100 110 240 250 260 270 280 pF1KB4 VR-RYSVDQEN-NMMVLVSRAVEHPSVPESPEFVRVRSYESQMVIRPHKSFDENGFDYLL .: : ..:.:. .. :...:.. :.. : .::..:.....: .: ..: .. CCDS11 LRQRRDLDMEGRKIHVILARSTSMPQLGERSGVIRVKQYKQSLAI---ESDGKKGSKVFM 120 130 140 150 160 170 290 300 310 320 330 340 pF1KB4 TYSDNPQTVFPRYCVSWMVSSGMPDFLEKLHMATLKAKNMEIKVKDYISAKPLEMSSEAK : ::: .: . ..: ...:.:.::. . : CCDS11 YYFDNPGGQIPSWLINWAAKNGVPNFLKDMARACQNYLKKT 180 190 200 210 350 360 370 pF1KB4 ATSQSSERKNEGSCGPARIEYA >>CCDS82165.1 PCTP gene_id:58488|Hs108|chr17 (203 aa) initn: 278 init1: 134 opt: 346 Z-score: 410.9 bits: 83.8 E(32554): 1.4e-16 Smith-Waterman score: 346; 30.2% identity (68.6% similar) in 172 aa overlap (141-310:30-195) 120 130 140 150 160 170 pF1KB4 MFQSSGVQHHPPEPKAQTEGNEDSEGKEQRWEMVMDKKHFKLWRRPITGTHLYQYRVFGT :..... . ....: : ::.:.:::. CCDS82 MELAAGSFSEEQFWEACAELQQPALAGADWQLLVETSGISIYRLLDKKTGLYEYKVFGV 10 20 30 40 50 180 190 200 210 220 230 pF1KB4 YTDVTPRQFFNVQLDTEYRKKWDALVIKLEVIERDVVSGSEVLHWVTHFPYPMYSRDYVY : .: . .. .:..:::.:: : :. :.. .: :..: ...:.:: .::::: CCDS82 LEDCSPTLLADIYMDSDYRKQWDQYVK--ELYEQEC-NGETVVYWEVKYPFPMSNRDYVY 60 70 80 90 100 110 240 250 260 270 280 pF1KB4 VR-RYSVDQEN-NMMVLVSRAVEHPSVPESPEFVRVRSYESQMVIRPHKSFDENGFDYLL .: : ..:.:. .. :...:.. :.. : .::..:.....: .: ..: .. CCDS82 LRQRRDLDMEGRKIHVILARSTSMPQLGERSGVIRVKQYKQSLAI---ESDGKKGSKVFM 120 130 140 150 160 170 290 300 310 320 330 340 pF1KB4 TYSDNPQTVFPRYCVSWMVSSGMPDFLEKLHMATLKAKNMEIKVKDYISAKPLEMSSEAK : ::: .: . ..: ...: CCDS82 YYFDNPGGQIPSWLINWAAKGGNCSGSLYH 180 190 200 >>CCDS82166.1 PCTP gene_id:58488|Hs108|chr17 (219 aa) initn: 275 init1: 131 opt: 339 Z-score: 402.2 bits: 82.3 E(32554): 4.4e-16 Smith-Waterman score: 339; 30.5% identity (68.3% similar) in 167 aa overlap (141-305:30-190) 120 130 140 150 160 170 pF1KB4 MFQSSGVQHHPPEPKAQTEGNEDSEGKEQRWEMVMDKKHFKLWRRPITGTHLYQYRVFGT :..... . ....: : ::.:.:::. CCDS82 MELAAGSFSEEQFWEACAELQQPALAGADWQLLVETSGISIYRLLDKKTGLYEYKVFGV 10 20 30 40 50 180 190 200 210 220 230 pF1KB4 YTDVTPRQFFNVQLDTEYRKKWDALVIKLEVIERDVVSGSEVLHWVTHFPYPMYSRDYVY : .: . .. .:..:::.:: : :. :.. .: :..: ...:.:: .::::: CCDS82 LEDCSPTLLADIYMDSDYRKQWDQYV--KELYEQEC-NGETVVYWEVKYPFPMSNRDYVY 60 70 80 90 100 110 240 250 260 270 280 pF1KB4 VR-RYSVDQEN-NMMVLVSRAVEHPSVPESPEFVRVRSYESQMVIRPHKSFDENGFDYLL .: : ..:.:. .. :...:.. :.. : .::..:.....: .: ..: .. CCDS82 LRQRRDLDMEGRKIHVILARSTSMPQLGERSGVIRVKQYKQSLAI---ESDGKKGSKVFM 120 130 140 150 160 170 290 300 310 320 330 340 pF1KB4 TYSDNPQTVFPRYCVSWMVSSGMPDFLEKLHMATLKAKNMEIKVKDYISAKPLEMSSEAK : ::: .: . ..: CCDS82 YYFDNPGGQIPSWLINWAAKNQSRTKREAQNQRDLIKFLANPNILQ 180 190 200 210 >>CCDS45741.1 PCTP gene_id:58488|Hs108|chr17 (142 aa) initn: 229 init1: 85 opt: 292 Z-score: 350.2 bits: 72.1 E(32554): 3.5e-13 Smith-Waterman score: 292; 32.1% identity (70.0% similar) in 140 aa overlap (184-321:1-134) 160 170 180 190 200 210 pF1KB4 RRPITGTHLYQYRVFGTYTDVTPRQFFNVQLDTEYRKKWDALVIKLEVIERDVVSGSEVL .:..:::.:: : :. :.. .: :. CCDS45 MDSDYRKQWDQYVK--ELYEQEC-NGETVV 10 20 220 230 240 250 260 270 pF1KB4 HWVTHFPYPMYSRDYVYVR-RYSVDQEN-NMMVLVSRAVEHPSVPESPEFVRVRSYESQM .: ...:.:: .:::::.: : ..:.:. .. :...:.. :.. : .::..:.... CCDS45 YWEVKYPFPMSNRDYVYLRQRRDLDMEGRKIHVILARSTSMPQLGERSGVIRVKQYKQSL 30 40 50 60 70 80 280 290 300 310 320 330 pF1KB4 VIRPHKSFDENGFDYLLTYSDNPQTVFPRYCVSWMVSSGMPDFLEKLHMATLKAKNMEIK .: .: ..: .. : ::: .: . ..: ...:.:.::. . : CCDS45 AI---ESDGKKGSKVFMYYFDNPGGQIPSWLINWAAKNGVPNFLKDMARACQNYLKKT 90 100 110 120 130 140 340 350 360 370 pF1KB4 VKDYISAKPLEMSSEAKATSQSSERKNEGSCGPARIEYA 370 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 12:19:54 2016 done: Sat Nov 5 12:19:55 2016 Total Scan time: 2.840 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]