FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB4575, 885 aa 1>>>pF1KB4575 885 - 885 aa - 885 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.3184+/-0.000456; mu= 12.4404+/- 0.029 mean_var=149.3768+/-30.033, 0's: 0 Z-trim(115.2): 50 B-trim: 166 in 2/49 Lambda= 0.104938 statistics sampled from 25468 (25518) to 25468 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.654), E-opt: 0.2 (0.299), width: 16 Scan time: 14.260 The best scores are: opt bits E(85289) XP_011543393 (OMIM: 610881) PREDICTED: histone-lys ( 885) 5897 905.5 0 XP_005274092 (OMIM: 610881) PREDICTED: histone-lys ( 885) 5897 905.5 0 NP_060105 (OMIM: 610881) histone-lysine N-methyltr ( 885) 5897 905.5 0 XP_011543394 (OMIM: 610881) PREDICTED: histone-lys ( 814) 5413 832.2 0 XP_005274093 (OMIM: 610881) PREDICTED: histone-lys ( 862) 5060 778.8 0 XP_006718644 (OMIM: 610881) PREDICTED: histone-lys ( 862) 5060 778.8 0 XP_016873365 (OMIM: 610881) PREDICTED: histone-lys ( 713) 4729 728.6 2.5e-209 XP_016873368 (OMIM: 610881) PREDICTED: histone-lys ( 713) 4729 728.6 2.5e-209 NP_001287836 (OMIM: 610881) histone-lysine N-methy ( 713) 4729 728.6 2.5e-209 XP_016873367 (OMIM: 610881) PREDICTED: histone-lys ( 713) 4729 728.6 2.5e-209 XP_016873366 (OMIM: 610881) PREDICTED: histone-lys ( 713) 4729 728.6 2.5e-209 NP_001287837 (OMIM: 610881) histone-lysine N-methy ( 645) 4282 660.9 5.4e-189 XP_011543395 (OMIM: 610881) PREDICTED: histone-lys ( 471) 3101 482.0 2.8e-135 XP_011543396 (OMIM: 610881) PREDICTED: histone-lys ( 393) 2664 415.8 2e-115 NP_057112 (OMIM: 610881) histone-lysine N-methyltr ( 393) 2664 415.8 2e-115 XP_016873369 (OMIM: 610881) PREDICTED: histone-lys ( 402) 2662 415.5 2.5e-115 NP_001287838 (OMIM: 610881) histone-lysine N-methy ( 370) 1827 289.1 2.7e-77 NP_116090 (OMIM: 613198) histone-lysine N-methyltr ( 462) 983 161.4 9.3e-39 XP_011525717 (OMIM: 613198) PREDICTED: histone-lys ( 462) 983 161.4 9.3e-39 XP_005259395 (OMIM: 613198) PREDICTED: histone-lys ( 347) 751 126.1 2.8e-28 XP_006723505 (OMIM: 613198) PREDICTED: histone-lys ( 347) 751 126.1 2.8e-28 XP_016882877 (OMIM: 613198) PREDICTED: histone-lys ( 298) 346 64.8 7.2e-10 >>XP_011543393 (OMIM: 610881) PREDICTED: histone-lysine (885 aa) initn: 5897 init1: 5897 opt: 5897 Z-score: 4833.5 bits: 905.5 E(85289): 0 Smith-Waterman score: 5897; 100.0% identity (100.0% similar) in 885 aa overlap (1-885:1-885) 10 20 30 40 50 60 pF1KB4 MKWLGESKNMVVNGRRNGGKLSNDHQQNQSKLQHTGKDTLKAGKNAVERRSNRCNGNSGF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MKWLGESKNMVVNGRRNGGKLSNDHQQNQSKLQHTGKDTLKAGKNAVERRSNRCNGNSGF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 EGQSRYVPSSGMSAKELCENDDLATSLVLDPYLGFQTHKMNTSAFPSRSSRHFSKSDSFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EGQSRYVPSSGMSAKELCENDDLATSLVLDPYLGFQTHKMNTSAFPSRSSRHFSKSDSFS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 HNNPVRFRPIKGRQEELKEVIERFKKDEHLEKAFKCLTSGEWARHYFLNKNKMQEKLFKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HNNPVRFRPIKGRQEELKEVIERFKKDEHLEKAFKCLTSGEWARHYFLNKNKMQEKLFKE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 HVFIYLRMFATDSGFEILPCNRYSSEQNGAKIVATKEWKRNDKIELLVGCIAELSEIEEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HVFIYLRMFATDSGFEILPCNRYSSEQNGAKIVATKEWKRNDKIELLVGCIAELSEIEEN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 MLLRHGENDFSVMYSTRKNCAQLWLGPAAFINHDCRPNCKFVSTGRDTACVKALRDIEPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MLLRHGENDFSVMYSTRKNCAQLWLGPAAFINHDCRPNCKFVSTGRDTACVKALRDIEPG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 EEISCYYGDGFFGENNEFCECYTCERRGTGAFKSRVGLPAPAPVINSKYGLRETDKRLNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EEISCYYGDGFFGENNEFCECYTCERRGTGAFKSRVGLPAPAPVINSKYGLRETDKRLNR 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB4 LKKLGDSSKNSDSQSVSSNTDADTTQEKNNATSNRKSSVGVKKNSKSRTLTRQSMSRIPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LKKLGDSSKNSDSQSVSSNTDADTTQEKNNATSNRKSSVGVKKNSKSRTLTRQSMSRIPA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB4 SSNSTSSKLTHINNSRVPKKLKKPAKPLLSKIKLRNHCKRLEQKNASRKLEMGNLVLKEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SSNSTSSKLTHINNSRVPKKLKKPAKPLLSKIKLRNHCKRLEQKNASRKLEMGNLVLKEP 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB4 KVVLYKNLPIKKDKEPEGPAQAAVASGCLTRHAAREHRQNPVRGAHSQGESSPCTYITRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KVVLYKNLPIKKDKEPEGPAQAAVASGCLTRHAAREHRQNPVRGAHSQGESSPCTYITRR 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB4 SVRTRTNLKEASDIKLEPNTLNGYKSSVTEPCPDSGEQLQPAPVLQEEELAHETAQKGEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SVRTRTNLKEASDIKLEPNTLNGYKSSVTEPCPDSGEQLQPAPVLQEEELAHETAQKGEA 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB4 KCHKSDTGMSKKKSRQGKLVKQFAKIEESTPVHDSPGKDDAVPDLMGPHSDQGEHSGTVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KCHKSDTGMSKKKSRQGKLVKQFAKIEESTPVHDSPGKDDAVPDLMGPHSDQGEHSGTVG 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB4 VPVSYTDCAPSPVGCSVVTSDSFKTKDSFRTAKSKKKRRITRYDAQLILENNSGIPKLTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VPVSYTDCAPSPVGCSVVTSDSFKTKDSFRTAKSKKKRRITRYDAQLILENNSGIPKLTL 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB4 RRRHDSSSKTNDQENDGMNSSKISIKLSKDHDNDNNLYVAKLNNGFNSGSGSSSTKLKIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RRRHDSSSKTNDQENDGMNSSKISIKLSKDHDNDNNLYVAKLNNGFNSGSGSSSTKLKIQ 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB4 LKRDEENRGSYTEGLHENGVCCSDPLSLLESRMEVDDYSQYEEESTDDSSSSEGDEEEDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LKRDEENRGSYTEGLHENGVCCSDPLSLLESRMEVDDYSQYEEESTDDSSSSEGDEEEDD 790 800 810 820 830 840 850 860 870 880 pF1KB4 YDDDFEDDFIPLPPAKRLRLIVGKDSIDIDISSRRREDQSLRLNA ::::::::::::::::::::::::::::::::::::::::::::: XP_011 YDDDFEDDFIPLPPAKRLRLIVGKDSIDIDISSRRREDQSLRLNA 850 860 870 880 >>XP_005274092 (OMIM: 610881) PREDICTED: histone-lysine (885 aa) initn: 5897 init1: 5897 opt: 5897 Z-score: 4833.5 bits: 905.5 E(85289): 0 Smith-Waterman score: 5897; 100.0% identity (100.0% similar) in 885 aa overlap (1-885:1-885) 10 20 30 40 50 60 pF1KB4 MKWLGESKNMVVNGRRNGGKLSNDHQQNQSKLQHTGKDTLKAGKNAVERRSNRCNGNSGF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MKWLGESKNMVVNGRRNGGKLSNDHQQNQSKLQHTGKDTLKAGKNAVERRSNRCNGNSGF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 EGQSRYVPSSGMSAKELCENDDLATSLVLDPYLGFQTHKMNTSAFPSRSSRHFSKSDSFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EGQSRYVPSSGMSAKELCENDDLATSLVLDPYLGFQTHKMNTSAFPSRSSRHFSKSDSFS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 HNNPVRFRPIKGRQEELKEVIERFKKDEHLEKAFKCLTSGEWARHYFLNKNKMQEKLFKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HNNPVRFRPIKGRQEELKEVIERFKKDEHLEKAFKCLTSGEWARHYFLNKNKMQEKLFKE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 HVFIYLRMFATDSGFEILPCNRYSSEQNGAKIVATKEWKRNDKIELLVGCIAELSEIEEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HVFIYLRMFATDSGFEILPCNRYSSEQNGAKIVATKEWKRNDKIELLVGCIAELSEIEEN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 MLLRHGENDFSVMYSTRKNCAQLWLGPAAFINHDCRPNCKFVSTGRDTACVKALRDIEPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MLLRHGENDFSVMYSTRKNCAQLWLGPAAFINHDCRPNCKFVSTGRDTACVKALRDIEPG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 EEISCYYGDGFFGENNEFCECYTCERRGTGAFKSRVGLPAPAPVINSKYGLRETDKRLNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EEISCYYGDGFFGENNEFCECYTCERRGTGAFKSRVGLPAPAPVINSKYGLRETDKRLNR 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB4 LKKLGDSSKNSDSQSVSSNTDADTTQEKNNATSNRKSSVGVKKNSKSRTLTRQSMSRIPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LKKLGDSSKNSDSQSVSSNTDADTTQEKNNATSNRKSSVGVKKNSKSRTLTRQSMSRIPA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB4 SSNSTSSKLTHINNSRVPKKLKKPAKPLLSKIKLRNHCKRLEQKNASRKLEMGNLVLKEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SSNSTSSKLTHINNSRVPKKLKKPAKPLLSKIKLRNHCKRLEQKNASRKLEMGNLVLKEP 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB4 KVVLYKNLPIKKDKEPEGPAQAAVASGCLTRHAAREHRQNPVRGAHSQGESSPCTYITRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KVVLYKNLPIKKDKEPEGPAQAAVASGCLTRHAAREHRQNPVRGAHSQGESSPCTYITRR 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB4 SVRTRTNLKEASDIKLEPNTLNGYKSSVTEPCPDSGEQLQPAPVLQEEELAHETAQKGEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SVRTRTNLKEASDIKLEPNTLNGYKSSVTEPCPDSGEQLQPAPVLQEEELAHETAQKGEA 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB4 KCHKSDTGMSKKKSRQGKLVKQFAKIEESTPVHDSPGKDDAVPDLMGPHSDQGEHSGTVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KCHKSDTGMSKKKSRQGKLVKQFAKIEESTPVHDSPGKDDAVPDLMGPHSDQGEHSGTVG 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB4 VPVSYTDCAPSPVGCSVVTSDSFKTKDSFRTAKSKKKRRITRYDAQLILENNSGIPKLTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VPVSYTDCAPSPVGCSVVTSDSFKTKDSFRTAKSKKKRRITRYDAQLILENNSGIPKLTL 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB4 RRRHDSSSKTNDQENDGMNSSKISIKLSKDHDNDNNLYVAKLNNGFNSGSGSSSTKLKIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RRRHDSSSKTNDQENDGMNSSKISIKLSKDHDNDNNLYVAKLNNGFNSGSGSSSTKLKIQ 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB4 LKRDEENRGSYTEGLHENGVCCSDPLSLLESRMEVDDYSQYEEESTDDSSSSEGDEEEDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LKRDEENRGSYTEGLHENGVCCSDPLSLLESRMEVDDYSQYEEESTDDSSSSEGDEEEDD 790 800 810 820 830 840 850 860 870 880 pF1KB4 YDDDFEDDFIPLPPAKRLRLIVGKDSIDIDISSRRREDQSLRLNA ::::::::::::::::::::::::::::::::::::::::::::: XP_005 YDDDFEDDFIPLPPAKRLRLIVGKDSIDIDISSRRREDQSLRLNA 850 860 870 880 >>NP_060105 (OMIM: 610881) histone-lysine N-methyltransf (885 aa) initn: 5897 init1: 5897 opt: 5897 Z-score: 4833.5 bits: 905.5 E(85289): 0 Smith-Waterman score: 5897; 100.0% identity (100.0% similar) in 885 aa overlap (1-885:1-885) 10 20 30 40 50 60 pF1KB4 MKWLGESKNMVVNGRRNGGKLSNDHQQNQSKLQHTGKDTLKAGKNAVERRSNRCNGNSGF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 MKWLGESKNMVVNGRRNGGKLSNDHQQNQSKLQHTGKDTLKAGKNAVERRSNRCNGNSGF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 EGQSRYVPSSGMSAKELCENDDLATSLVLDPYLGFQTHKMNTSAFPSRSSRHFSKSDSFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 EGQSRYVPSSGMSAKELCENDDLATSLVLDPYLGFQTHKMNTSAFPSRSSRHFSKSDSFS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 HNNPVRFRPIKGRQEELKEVIERFKKDEHLEKAFKCLTSGEWARHYFLNKNKMQEKLFKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 HNNPVRFRPIKGRQEELKEVIERFKKDEHLEKAFKCLTSGEWARHYFLNKNKMQEKLFKE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 HVFIYLRMFATDSGFEILPCNRYSSEQNGAKIVATKEWKRNDKIELLVGCIAELSEIEEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 HVFIYLRMFATDSGFEILPCNRYSSEQNGAKIVATKEWKRNDKIELLVGCIAELSEIEEN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 MLLRHGENDFSVMYSTRKNCAQLWLGPAAFINHDCRPNCKFVSTGRDTACVKALRDIEPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 MLLRHGENDFSVMYSTRKNCAQLWLGPAAFINHDCRPNCKFVSTGRDTACVKALRDIEPG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 EEISCYYGDGFFGENNEFCECYTCERRGTGAFKSRVGLPAPAPVINSKYGLRETDKRLNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 EEISCYYGDGFFGENNEFCECYTCERRGTGAFKSRVGLPAPAPVINSKYGLRETDKRLNR 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB4 LKKLGDSSKNSDSQSVSSNTDADTTQEKNNATSNRKSSVGVKKNSKSRTLTRQSMSRIPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 LKKLGDSSKNSDSQSVSSNTDADTTQEKNNATSNRKSSVGVKKNSKSRTLTRQSMSRIPA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB4 SSNSTSSKLTHINNSRVPKKLKKPAKPLLSKIKLRNHCKRLEQKNASRKLEMGNLVLKEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 SSNSTSSKLTHINNSRVPKKLKKPAKPLLSKIKLRNHCKRLEQKNASRKLEMGNLVLKEP 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB4 KVVLYKNLPIKKDKEPEGPAQAAVASGCLTRHAAREHRQNPVRGAHSQGESSPCTYITRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 KVVLYKNLPIKKDKEPEGPAQAAVASGCLTRHAAREHRQNPVRGAHSQGESSPCTYITRR 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB4 SVRTRTNLKEASDIKLEPNTLNGYKSSVTEPCPDSGEQLQPAPVLQEEELAHETAQKGEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 SVRTRTNLKEASDIKLEPNTLNGYKSSVTEPCPDSGEQLQPAPVLQEEELAHETAQKGEA 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB4 KCHKSDTGMSKKKSRQGKLVKQFAKIEESTPVHDSPGKDDAVPDLMGPHSDQGEHSGTVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 KCHKSDTGMSKKKSRQGKLVKQFAKIEESTPVHDSPGKDDAVPDLMGPHSDQGEHSGTVG 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB4 VPVSYTDCAPSPVGCSVVTSDSFKTKDSFRTAKSKKKRRITRYDAQLILENNSGIPKLTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 VPVSYTDCAPSPVGCSVVTSDSFKTKDSFRTAKSKKKRRITRYDAQLILENNSGIPKLTL 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB4 RRRHDSSSKTNDQENDGMNSSKISIKLSKDHDNDNNLYVAKLNNGFNSGSGSSSTKLKIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 RRRHDSSSKTNDQENDGMNSSKISIKLSKDHDNDNNLYVAKLNNGFNSGSGSSSTKLKIQ 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB4 LKRDEENRGSYTEGLHENGVCCSDPLSLLESRMEVDDYSQYEEESTDDSSSSEGDEEEDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 LKRDEENRGSYTEGLHENGVCCSDPLSLLESRMEVDDYSQYEEESTDDSSSSEGDEEEDD 790 800 810 820 830 840 850 860 870 880 pF1KB4 YDDDFEDDFIPLPPAKRLRLIVGKDSIDIDISSRRREDQSLRLNA ::::::::::::::::::::::::::::::::::::::::::::: NP_060 YDDDFEDDFIPLPPAKRLRLIVGKDSIDIDISSRRREDQSLRLNA 850 860 870 880 >>XP_011543394 (OMIM: 610881) PREDICTED: histone-lysine (814 aa) initn: 5413 init1: 5413 opt: 5413 Z-score: 4438.0 bits: 832.2 E(85289): 0 Smith-Waterman score: 5413; 100.0% identity (100.0% similar) in 814 aa overlap (72-885:1-814) 50 60 70 80 90 100 pF1KB4 AGKNAVERRSNRCNGNSGFEGQSRYVPSSGMSAKELCENDDLATSLVLDPYLGFQTHKMN :::::::::::::::::::::::::::::: XP_011 MSAKELCENDDLATSLVLDPYLGFQTHKMN 10 20 30 110 120 130 140 150 160 pF1KB4 TSAFPSRSSRHFSKSDSFSHNNPVRFRPIKGRQEELKEVIERFKKDEHLEKAFKCLTSGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TSAFPSRSSRHFSKSDSFSHNNPVRFRPIKGRQEELKEVIERFKKDEHLEKAFKCLTSGE 40 50 60 70 80 90 170 180 190 200 210 220 pF1KB4 WARHYFLNKNKMQEKLFKEHVFIYLRMFATDSGFEILPCNRYSSEQNGAKIVATKEWKRN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WARHYFLNKNKMQEKLFKEHVFIYLRMFATDSGFEILPCNRYSSEQNGAKIVATKEWKRN 100 110 120 130 140 150 230 240 250 260 270 280 pF1KB4 DKIELLVGCIAELSEIEENMLLRHGENDFSVMYSTRKNCAQLWLGPAAFINHDCRPNCKF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DKIELLVGCIAELSEIEENMLLRHGENDFSVMYSTRKNCAQLWLGPAAFINHDCRPNCKF 160 170 180 190 200 210 290 300 310 320 330 340 pF1KB4 VSTGRDTACVKALRDIEPGEEISCYYGDGFFGENNEFCECYTCERRGTGAFKSRVGLPAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VSTGRDTACVKALRDIEPGEEISCYYGDGFFGENNEFCECYTCERRGTGAFKSRVGLPAP 220 230 240 250 260 270 350 360 370 380 390 400 pF1KB4 APVINSKYGLRETDKRLNRLKKLGDSSKNSDSQSVSSNTDADTTQEKNNATSNRKSSVGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 APVINSKYGLRETDKRLNRLKKLGDSSKNSDSQSVSSNTDADTTQEKNNATSNRKSSVGV 280 290 300 310 320 330 410 420 430 440 450 460 pF1KB4 KKNSKSRTLTRQSMSRIPASSNSTSSKLTHINNSRVPKKLKKPAKPLLSKIKLRNHCKRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KKNSKSRTLTRQSMSRIPASSNSTSSKLTHINNSRVPKKLKKPAKPLLSKIKLRNHCKRL 340 350 360 370 380 390 470 480 490 500 510 520 pF1KB4 EQKNASRKLEMGNLVLKEPKVVLYKNLPIKKDKEPEGPAQAAVASGCLTRHAAREHRQNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EQKNASRKLEMGNLVLKEPKVVLYKNLPIKKDKEPEGPAQAAVASGCLTRHAAREHRQNP 400 410 420 430 440 450 530 540 550 560 570 580 pF1KB4 VRGAHSQGESSPCTYITRRSVRTRTNLKEASDIKLEPNTLNGYKSSVTEPCPDSGEQLQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VRGAHSQGESSPCTYITRRSVRTRTNLKEASDIKLEPNTLNGYKSSVTEPCPDSGEQLQP 460 470 480 490 500 510 590 600 610 620 630 640 pF1KB4 APVLQEEELAHETAQKGEAKCHKSDTGMSKKKSRQGKLVKQFAKIEESTPVHDSPGKDDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 APVLQEEELAHETAQKGEAKCHKSDTGMSKKKSRQGKLVKQFAKIEESTPVHDSPGKDDA 520 530 540 550 560 570 650 660 670 680 690 700 pF1KB4 VPDLMGPHSDQGEHSGTVGVPVSYTDCAPSPVGCSVVTSDSFKTKDSFRTAKSKKKRRIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VPDLMGPHSDQGEHSGTVGVPVSYTDCAPSPVGCSVVTSDSFKTKDSFRTAKSKKKRRIT 580 590 600 610 620 630 710 720 730 740 750 760 pF1KB4 RYDAQLILENNSGIPKLTLRRRHDSSSKTNDQENDGMNSSKISIKLSKDHDNDNNLYVAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RYDAQLILENNSGIPKLTLRRRHDSSSKTNDQENDGMNSSKISIKLSKDHDNDNNLYVAK 640 650 660 670 680 690 770 780 790 800 810 820 pF1KB4 LNNGFNSGSGSSSTKLKIQLKRDEENRGSYTEGLHENGVCCSDPLSLLESRMEVDDYSQY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LNNGFNSGSGSSSTKLKIQLKRDEENRGSYTEGLHENGVCCSDPLSLLESRMEVDDYSQY 700 710 720 730 740 750 830 840 850 860 870 880 pF1KB4 EEESTDDSSSSEGDEEEDDYDDDFEDDFIPLPPAKRLRLIVGKDSIDIDISSRRREDQSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EEESTDDSSSSEGDEEEDDYDDDFEDDFIPLPPAKRLRLIVGKDSIDIDISSRRREDQSL 760 770 780 790 800 810 pF1KB4 RLNA :::: XP_011 RLNA >>XP_005274093 (OMIM: 610881) PREDICTED: histone-lysine (862 aa) initn: 5060 init1: 5060 opt: 5060 Z-score: 4148.8 bits: 778.8 E(85289): 0 Smith-Waterman score: 5685; 97.4% identity (97.4% similar) in 885 aa overlap (1-885:1-862) 10 20 30 40 50 60 pF1KB4 MKWLGESKNMVVNGRRNGGKLSNDHQQNQSKLQHTGKDTLKAGKNAVERRSNRCNGNSGF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MKWLGESKNMVVNGRRNGGKLSNDHQQNQSKLQHTGKDTLKAGKNAVERRSNRCNGNSGF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 EGQSRYVPSSGMSAKELCENDDLATSLVLDPYLGFQTHKMNTSAFPSRSSRHFSKSDSFS :::::::::::::::::::::::::::::::::::::::::: XP_005 EGQSRYVPSSGMSAKELCENDDLATSLVLDPYLGFQTHKMNT------------------ 70 80 90 100 130 140 150 160 170 180 pF1KB4 HNNPVRFRPIKGRQEELKEVIERFKKDEHLEKAFKCLTSGEWARHYFLNKNKMQEKLFKE ::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 -----RFRPIKGRQEELKEVIERFKKDEHLEKAFKCLTSGEWARHYFLNKNKMQEKLFKE 110 120 130 140 150 190 200 210 220 230 240 pF1KB4 HVFIYLRMFATDSGFEILPCNRYSSEQNGAKIVATKEWKRNDKIELLVGCIAELSEIEEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HVFIYLRMFATDSGFEILPCNRYSSEQNGAKIVATKEWKRNDKIELLVGCIAELSEIEEN 160 170 180 190 200 210 250 260 270 280 290 300 pF1KB4 MLLRHGENDFSVMYSTRKNCAQLWLGPAAFINHDCRPNCKFVSTGRDTACVKALRDIEPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MLLRHGENDFSVMYSTRKNCAQLWLGPAAFINHDCRPNCKFVSTGRDTACVKALRDIEPG 220 230 240 250 260 270 310 320 330 340 350 360 pF1KB4 EEISCYYGDGFFGENNEFCECYTCERRGTGAFKSRVGLPAPAPVINSKYGLRETDKRLNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EEISCYYGDGFFGENNEFCECYTCERRGTGAFKSRVGLPAPAPVINSKYGLRETDKRLNR 280 290 300 310 320 330 370 380 390 400 410 420 pF1KB4 LKKLGDSSKNSDSQSVSSNTDADTTQEKNNATSNRKSSVGVKKNSKSRTLTRQSMSRIPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LKKLGDSSKNSDSQSVSSNTDADTTQEKNNATSNRKSSVGVKKNSKSRTLTRQSMSRIPA 340 350 360 370 380 390 430 440 450 460 470 480 pF1KB4 SSNSTSSKLTHINNSRVPKKLKKPAKPLLSKIKLRNHCKRLEQKNASRKLEMGNLVLKEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SSNSTSSKLTHINNSRVPKKLKKPAKPLLSKIKLRNHCKRLEQKNASRKLEMGNLVLKEP 400 410 420 430 440 450 490 500 510 520 530 540 pF1KB4 KVVLYKNLPIKKDKEPEGPAQAAVASGCLTRHAAREHRQNPVRGAHSQGESSPCTYITRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KVVLYKNLPIKKDKEPEGPAQAAVASGCLTRHAAREHRQNPVRGAHSQGESSPCTYITRR 460 470 480 490 500 510 550 560 570 580 590 600 pF1KB4 SVRTRTNLKEASDIKLEPNTLNGYKSSVTEPCPDSGEQLQPAPVLQEEELAHETAQKGEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SVRTRTNLKEASDIKLEPNTLNGYKSSVTEPCPDSGEQLQPAPVLQEEELAHETAQKGEA 520 530 540 550 560 570 610 620 630 640 650 660 pF1KB4 KCHKSDTGMSKKKSRQGKLVKQFAKIEESTPVHDSPGKDDAVPDLMGPHSDQGEHSGTVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KCHKSDTGMSKKKSRQGKLVKQFAKIEESTPVHDSPGKDDAVPDLMGPHSDQGEHSGTVG 580 590 600 610 620 630 670 680 690 700 710 720 pF1KB4 VPVSYTDCAPSPVGCSVVTSDSFKTKDSFRTAKSKKKRRITRYDAQLILENNSGIPKLTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VPVSYTDCAPSPVGCSVVTSDSFKTKDSFRTAKSKKKRRITRYDAQLILENNSGIPKLTL 640 650 660 670 680 690 730 740 750 760 770 780 pF1KB4 RRRHDSSSKTNDQENDGMNSSKISIKLSKDHDNDNNLYVAKLNNGFNSGSGSSSTKLKIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RRRHDSSSKTNDQENDGMNSSKISIKLSKDHDNDNNLYVAKLNNGFNSGSGSSSTKLKIQ 700 710 720 730 740 750 790 800 810 820 830 840 pF1KB4 LKRDEENRGSYTEGLHENGVCCSDPLSLLESRMEVDDYSQYEEESTDDSSSSEGDEEEDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LKRDEENRGSYTEGLHENGVCCSDPLSLLESRMEVDDYSQYEEESTDDSSSSEGDEEEDD 760 770 780 790 800 810 850 860 870 880 pF1KB4 YDDDFEDDFIPLPPAKRLRLIVGKDSIDIDISSRRREDQSLRLNA ::::::::::::::::::::::::::::::::::::::::::::: XP_005 YDDDFEDDFIPLPPAKRLRLIVGKDSIDIDISSRRREDQSLRLNA 820 830 840 850 860 >>XP_006718644 (OMIM: 610881) PREDICTED: histone-lysine (862 aa) initn: 5060 init1: 5060 opt: 5060 Z-score: 4148.8 bits: 778.8 E(85289): 0 Smith-Waterman score: 5685; 97.4% identity (97.4% similar) in 885 aa overlap (1-885:1-862) 10 20 30 40 50 60 pF1KB4 MKWLGESKNMVVNGRRNGGKLSNDHQQNQSKLQHTGKDTLKAGKNAVERRSNRCNGNSGF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MKWLGESKNMVVNGRRNGGKLSNDHQQNQSKLQHTGKDTLKAGKNAVERRSNRCNGNSGF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 EGQSRYVPSSGMSAKELCENDDLATSLVLDPYLGFQTHKMNTSAFPSRSSRHFSKSDSFS :::::::::::::::::::::::::::::::::::::::::: XP_006 EGQSRYVPSSGMSAKELCENDDLATSLVLDPYLGFQTHKMNT------------------ 70 80 90 100 130 140 150 160 170 180 pF1KB4 HNNPVRFRPIKGRQEELKEVIERFKKDEHLEKAFKCLTSGEWARHYFLNKNKMQEKLFKE ::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 -----RFRPIKGRQEELKEVIERFKKDEHLEKAFKCLTSGEWARHYFLNKNKMQEKLFKE 110 120 130 140 150 190 200 210 220 230 240 pF1KB4 HVFIYLRMFATDSGFEILPCNRYSSEQNGAKIVATKEWKRNDKIELLVGCIAELSEIEEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 HVFIYLRMFATDSGFEILPCNRYSSEQNGAKIVATKEWKRNDKIELLVGCIAELSEIEEN 160 170 180 190 200 210 250 260 270 280 290 300 pF1KB4 MLLRHGENDFSVMYSTRKNCAQLWLGPAAFINHDCRPNCKFVSTGRDTACVKALRDIEPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MLLRHGENDFSVMYSTRKNCAQLWLGPAAFINHDCRPNCKFVSTGRDTACVKALRDIEPG 220 230 240 250 260 270 310 320 330 340 350 360 pF1KB4 EEISCYYGDGFFGENNEFCECYTCERRGTGAFKSRVGLPAPAPVINSKYGLRETDKRLNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EEISCYYGDGFFGENNEFCECYTCERRGTGAFKSRVGLPAPAPVINSKYGLRETDKRLNR 280 290 300 310 320 330 370 380 390 400 410 420 pF1KB4 LKKLGDSSKNSDSQSVSSNTDADTTQEKNNATSNRKSSVGVKKNSKSRTLTRQSMSRIPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LKKLGDSSKNSDSQSVSSNTDADTTQEKNNATSNRKSSVGVKKNSKSRTLTRQSMSRIPA 340 350 360 370 380 390 430 440 450 460 470 480 pF1KB4 SSNSTSSKLTHINNSRVPKKLKKPAKPLLSKIKLRNHCKRLEQKNASRKLEMGNLVLKEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SSNSTSSKLTHINNSRVPKKLKKPAKPLLSKIKLRNHCKRLEQKNASRKLEMGNLVLKEP 400 410 420 430 440 450 490 500 510 520 530 540 pF1KB4 KVVLYKNLPIKKDKEPEGPAQAAVASGCLTRHAAREHRQNPVRGAHSQGESSPCTYITRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KVVLYKNLPIKKDKEPEGPAQAAVASGCLTRHAAREHRQNPVRGAHSQGESSPCTYITRR 460 470 480 490 500 510 550 560 570 580 590 600 pF1KB4 SVRTRTNLKEASDIKLEPNTLNGYKSSVTEPCPDSGEQLQPAPVLQEEELAHETAQKGEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SVRTRTNLKEASDIKLEPNTLNGYKSSVTEPCPDSGEQLQPAPVLQEEELAHETAQKGEA 520 530 540 550 560 570 610 620 630 640 650 660 pF1KB4 KCHKSDTGMSKKKSRQGKLVKQFAKIEESTPVHDSPGKDDAVPDLMGPHSDQGEHSGTVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KCHKSDTGMSKKKSRQGKLVKQFAKIEESTPVHDSPGKDDAVPDLMGPHSDQGEHSGTVG 580 590 600 610 620 630 670 680 690 700 710 720 pF1KB4 VPVSYTDCAPSPVGCSVVTSDSFKTKDSFRTAKSKKKRRITRYDAQLILENNSGIPKLTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VPVSYTDCAPSPVGCSVVTSDSFKTKDSFRTAKSKKKRRITRYDAQLILENNSGIPKLTL 640 650 660 670 680 690 730 740 750 760 770 780 pF1KB4 RRRHDSSSKTNDQENDGMNSSKISIKLSKDHDNDNNLYVAKLNNGFNSGSGSSSTKLKIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RRRHDSSSKTNDQENDGMNSSKISIKLSKDHDNDNNLYVAKLNNGFNSGSGSSSTKLKIQ 700 710 720 730 740 750 790 800 810 820 830 840 pF1KB4 LKRDEENRGSYTEGLHENGVCCSDPLSLLESRMEVDDYSQYEEESTDDSSSSEGDEEEDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LKRDEENRGSYTEGLHENGVCCSDPLSLLESRMEVDDYSQYEEESTDDSSSSEGDEEEDD 760 770 780 790 800 810 850 860 870 880 pF1KB4 YDDDFEDDFIPLPPAKRLRLIVGKDSIDIDISSRRREDQSLRLNA ::::::::::::::::::::::::::::::::::::::::::::: XP_006 YDDDFEDDFIPLPPAKRLRLIVGKDSIDIDISSRRREDQSLRLNA 820 830 840 850 860 >>XP_016873365 (OMIM: 610881) PREDICTED: histone-lysine (713 aa) initn: 4729 init1: 4729 opt: 4729 Z-score: 3879.1 bits: 728.6 E(85289): 2.5e-209 Smith-Waterman score: 4729; 100.0% identity (100.0% similar) in 713 aa overlap (173-885:1-713) 150 160 170 180 190 200 pF1KB4 RFKKDEHLEKAFKCLTSGEWARHYFLNKNKMQEKLFKEHVFIYLRMFATDSGFEILPCNR :::::::::::::::::::::::::::::: XP_016 MQEKLFKEHVFIYLRMFATDSGFEILPCNR 10 20 30 210 220 230 240 250 260 pF1KB4 YSSEQNGAKIVATKEWKRNDKIELLVGCIAELSEIEENMLLRHGENDFSVMYSTRKNCAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YSSEQNGAKIVATKEWKRNDKIELLVGCIAELSEIEENMLLRHGENDFSVMYSTRKNCAQ 40 50 60 70 80 90 270 280 290 300 310 320 pF1KB4 LWLGPAAFINHDCRPNCKFVSTGRDTACVKALRDIEPGEEISCYYGDGFFGENNEFCECY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LWLGPAAFINHDCRPNCKFVSTGRDTACVKALRDIEPGEEISCYYGDGFFGENNEFCECY 100 110 120 130 140 150 330 340 350 360 370 380 pF1KB4 TCERRGTGAFKSRVGLPAPAPVINSKYGLRETDKRLNRLKKLGDSSKNSDSQSVSSNTDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TCERRGTGAFKSRVGLPAPAPVINSKYGLRETDKRLNRLKKLGDSSKNSDSQSVSSNTDA 160 170 180 190 200 210 390 400 410 420 430 440 pF1KB4 DTTQEKNNATSNRKSSVGVKKNSKSRTLTRQSMSRIPASSNSTSSKLTHINNSRVPKKLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DTTQEKNNATSNRKSSVGVKKNSKSRTLTRQSMSRIPASSNSTSSKLTHINNSRVPKKLK 220 230 240 250 260 270 450 460 470 480 490 500 pF1KB4 KPAKPLLSKIKLRNHCKRLEQKNASRKLEMGNLVLKEPKVVLYKNLPIKKDKEPEGPAQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KPAKPLLSKIKLRNHCKRLEQKNASRKLEMGNLVLKEPKVVLYKNLPIKKDKEPEGPAQA 280 290 300 310 320 330 510 520 530 540 550 560 pF1KB4 AVASGCLTRHAAREHRQNPVRGAHSQGESSPCTYITRRSVRTRTNLKEASDIKLEPNTLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AVASGCLTRHAAREHRQNPVRGAHSQGESSPCTYITRRSVRTRTNLKEASDIKLEPNTLN 340 350 360 370 380 390 570 580 590 600 610 620 pF1KB4 GYKSSVTEPCPDSGEQLQPAPVLQEEELAHETAQKGEAKCHKSDTGMSKKKSRQGKLVKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GYKSSVTEPCPDSGEQLQPAPVLQEEELAHETAQKGEAKCHKSDTGMSKKKSRQGKLVKQ 400 410 420 430 440 450 630 640 650 660 670 680 pF1KB4 FAKIEESTPVHDSPGKDDAVPDLMGPHSDQGEHSGTVGVPVSYTDCAPSPVGCSVVTSDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FAKIEESTPVHDSPGKDDAVPDLMGPHSDQGEHSGTVGVPVSYTDCAPSPVGCSVVTSDS 460 470 480 490 500 510 690 700 710 720 730 740 pF1KB4 FKTKDSFRTAKSKKKRRITRYDAQLILENNSGIPKLTLRRRHDSSSKTNDQENDGMNSSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FKTKDSFRTAKSKKKRRITRYDAQLILENNSGIPKLTLRRRHDSSSKTNDQENDGMNSSK 520 530 540 550 560 570 750 760 770 780 790 800 pF1KB4 ISIKLSKDHDNDNNLYVAKLNNGFNSGSGSSSTKLKIQLKRDEENRGSYTEGLHENGVCC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ISIKLSKDHDNDNNLYVAKLNNGFNSGSGSSSTKLKIQLKRDEENRGSYTEGLHENGVCC 580 590 600 610 620 630 810 820 830 840 850 860 pF1KB4 SDPLSLLESRMEVDDYSQYEEESTDDSSSSEGDEEEDDYDDDFEDDFIPLPPAKRLRLIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SDPLSLLESRMEVDDYSQYEEESTDDSSSSEGDEEEDDYDDDFEDDFIPLPPAKRLRLIV 640 650 660 670 680 690 870 880 pF1KB4 GKDSIDIDISSRRREDQSLRLNA ::::::::::::::::::::::: XP_016 GKDSIDIDISSRRREDQSLRLNA 700 710 >>XP_016873368 (OMIM: 610881) PREDICTED: histone-lysine (713 aa) initn: 4729 init1: 4729 opt: 4729 Z-score: 3879.1 bits: 728.6 E(85289): 2.5e-209 Smith-Waterman score: 4729; 100.0% identity (100.0% similar) in 713 aa overlap (173-885:1-713) 150 160 170 180 190 200 pF1KB4 RFKKDEHLEKAFKCLTSGEWARHYFLNKNKMQEKLFKEHVFIYLRMFATDSGFEILPCNR :::::::::::::::::::::::::::::: XP_016 MQEKLFKEHVFIYLRMFATDSGFEILPCNR 10 20 30 210 220 230 240 250 260 pF1KB4 YSSEQNGAKIVATKEWKRNDKIELLVGCIAELSEIEENMLLRHGENDFSVMYSTRKNCAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YSSEQNGAKIVATKEWKRNDKIELLVGCIAELSEIEENMLLRHGENDFSVMYSTRKNCAQ 40 50 60 70 80 90 270 280 290 300 310 320 pF1KB4 LWLGPAAFINHDCRPNCKFVSTGRDTACVKALRDIEPGEEISCYYGDGFFGENNEFCECY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LWLGPAAFINHDCRPNCKFVSTGRDTACVKALRDIEPGEEISCYYGDGFFGENNEFCECY 100 110 120 130 140 150 330 340 350 360 370 380 pF1KB4 TCERRGTGAFKSRVGLPAPAPVINSKYGLRETDKRLNRLKKLGDSSKNSDSQSVSSNTDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TCERRGTGAFKSRVGLPAPAPVINSKYGLRETDKRLNRLKKLGDSSKNSDSQSVSSNTDA 160 170 180 190 200 210 390 400 410 420 430 440 pF1KB4 DTTQEKNNATSNRKSSVGVKKNSKSRTLTRQSMSRIPASSNSTSSKLTHINNSRVPKKLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DTTQEKNNATSNRKSSVGVKKNSKSRTLTRQSMSRIPASSNSTSSKLTHINNSRVPKKLK 220 230 240 250 260 270 450 460 470 480 490 500 pF1KB4 KPAKPLLSKIKLRNHCKRLEQKNASRKLEMGNLVLKEPKVVLYKNLPIKKDKEPEGPAQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KPAKPLLSKIKLRNHCKRLEQKNASRKLEMGNLVLKEPKVVLYKNLPIKKDKEPEGPAQA 280 290 300 310 320 330 510 520 530 540 550 560 pF1KB4 AVASGCLTRHAAREHRQNPVRGAHSQGESSPCTYITRRSVRTRTNLKEASDIKLEPNTLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AVASGCLTRHAAREHRQNPVRGAHSQGESSPCTYITRRSVRTRTNLKEASDIKLEPNTLN 340 350 360 370 380 390 570 580 590 600 610 620 pF1KB4 GYKSSVTEPCPDSGEQLQPAPVLQEEELAHETAQKGEAKCHKSDTGMSKKKSRQGKLVKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GYKSSVTEPCPDSGEQLQPAPVLQEEELAHETAQKGEAKCHKSDTGMSKKKSRQGKLVKQ 400 410 420 430 440 450 630 640 650 660 670 680 pF1KB4 FAKIEESTPVHDSPGKDDAVPDLMGPHSDQGEHSGTVGVPVSYTDCAPSPVGCSVVTSDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FAKIEESTPVHDSPGKDDAVPDLMGPHSDQGEHSGTVGVPVSYTDCAPSPVGCSVVTSDS 460 470 480 490 500 510 690 700 710 720 730 740 pF1KB4 FKTKDSFRTAKSKKKRRITRYDAQLILENNSGIPKLTLRRRHDSSSKTNDQENDGMNSSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FKTKDSFRTAKSKKKRRITRYDAQLILENNSGIPKLTLRRRHDSSSKTNDQENDGMNSSK 520 530 540 550 560 570 750 760 770 780 790 800 pF1KB4 ISIKLSKDHDNDNNLYVAKLNNGFNSGSGSSSTKLKIQLKRDEENRGSYTEGLHENGVCC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ISIKLSKDHDNDNNLYVAKLNNGFNSGSGSSSTKLKIQLKRDEENRGSYTEGLHENGVCC 580 590 600 610 620 630 810 820 830 840 850 860 pF1KB4 SDPLSLLESRMEVDDYSQYEEESTDDSSSSEGDEEEDDYDDDFEDDFIPLPPAKRLRLIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SDPLSLLESRMEVDDYSQYEEESTDDSSSSEGDEEEDDYDDDFEDDFIPLPPAKRLRLIV 640 650 660 670 680 690 870 880 pF1KB4 GKDSIDIDISSRRREDQSLRLNA ::::::::::::::::::::::: XP_016 GKDSIDIDISSRRREDQSLRLNA 700 710 >>NP_001287836 (OMIM: 610881) histone-lysine N-methyltra (713 aa) initn: 4729 init1: 4729 opt: 4729 Z-score: 3879.1 bits: 728.6 E(85289): 2.5e-209 Smith-Waterman score: 4729; 100.0% identity (100.0% similar) in 713 aa overlap (173-885:1-713) 150 160 170 180 190 200 pF1KB4 RFKKDEHLEKAFKCLTSGEWARHYFLNKNKMQEKLFKEHVFIYLRMFATDSGFEILPCNR :::::::::::::::::::::::::::::: NP_001 MQEKLFKEHVFIYLRMFATDSGFEILPCNR 10 20 30 210 220 230 240 250 260 pF1KB4 YSSEQNGAKIVATKEWKRNDKIELLVGCIAELSEIEENMLLRHGENDFSVMYSTRKNCAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YSSEQNGAKIVATKEWKRNDKIELLVGCIAELSEIEENMLLRHGENDFSVMYSTRKNCAQ 40 50 60 70 80 90 270 280 290 300 310 320 pF1KB4 LWLGPAAFINHDCRPNCKFVSTGRDTACVKALRDIEPGEEISCYYGDGFFGENNEFCECY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LWLGPAAFINHDCRPNCKFVSTGRDTACVKALRDIEPGEEISCYYGDGFFGENNEFCECY 100 110 120 130 140 150 330 340 350 360 370 380 pF1KB4 TCERRGTGAFKSRVGLPAPAPVINSKYGLRETDKRLNRLKKLGDSSKNSDSQSVSSNTDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TCERRGTGAFKSRVGLPAPAPVINSKYGLRETDKRLNRLKKLGDSSKNSDSQSVSSNTDA 160 170 180 190 200 210 390 400 410 420 430 440 pF1KB4 DTTQEKNNATSNRKSSVGVKKNSKSRTLTRQSMSRIPASSNSTSSKLTHINNSRVPKKLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DTTQEKNNATSNRKSSVGVKKNSKSRTLTRQSMSRIPASSNSTSSKLTHINNSRVPKKLK 220 230 240 250 260 270 450 460 470 480 490 500 pF1KB4 KPAKPLLSKIKLRNHCKRLEQKNASRKLEMGNLVLKEPKVVLYKNLPIKKDKEPEGPAQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KPAKPLLSKIKLRNHCKRLEQKNASRKLEMGNLVLKEPKVVLYKNLPIKKDKEPEGPAQA 280 290 300 310 320 330 510 520 530 540 550 560 pF1KB4 AVASGCLTRHAAREHRQNPVRGAHSQGESSPCTYITRRSVRTRTNLKEASDIKLEPNTLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AVASGCLTRHAAREHRQNPVRGAHSQGESSPCTYITRRSVRTRTNLKEASDIKLEPNTLN 340 350 360 370 380 390 570 580 590 600 610 620 pF1KB4 GYKSSVTEPCPDSGEQLQPAPVLQEEELAHETAQKGEAKCHKSDTGMSKKKSRQGKLVKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GYKSSVTEPCPDSGEQLQPAPVLQEEELAHETAQKGEAKCHKSDTGMSKKKSRQGKLVKQ 400 410 420 430 440 450 630 640 650 660 670 680 pF1KB4 FAKIEESTPVHDSPGKDDAVPDLMGPHSDQGEHSGTVGVPVSYTDCAPSPVGCSVVTSDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FAKIEESTPVHDSPGKDDAVPDLMGPHSDQGEHSGTVGVPVSYTDCAPSPVGCSVVTSDS 460 470 480 490 500 510 690 700 710 720 730 740 pF1KB4 FKTKDSFRTAKSKKKRRITRYDAQLILENNSGIPKLTLRRRHDSSSKTNDQENDGMNSSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FKTKDSFRTAKSKKKRRITRYDAQLILENNSGIPKLTLRRRHDSSSKTNDQENDGMNSSK 520 530 540 550 560 570 750 760 770 780 790 800 pF1KB4 ISIKLSKDHDNDNNLYVAKLNNGFNSGSGSSSTKLKIQLKRDEENRGSYTEGLHENGVCC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ISIKLSKDHDNDNNLYVAKLNNGFNSGSGSSSTKLKIQLKRDEENRGSYTEGLHENGVCC 580 590 600 610 620 630 810 820 830 840 850 860 pF1KB4 SDPLSLLESRMEVDDYSQYEEESTDDSSSSEGDEEEDDYDDDFEDDFIPLPPAKRLRLIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SDPLSLLESRMEVDDYSQYEEESTDDSSSSEGDEEEDDYDDDFEDDFIPLPPAKRLRLIV 640 650 660 670 680 690 870 880 pF1KB4 GKDSIDIDISSRRREDQSLRLNA ::::::::::::::::::::::: NP_001 GKDSIDIDISSRRREDQSLRLNA 700 710 >>XP_016873367 (OMIM: 610881) PREDICTED: histone-lysine (713 aa) initn: 4729 init1: 4729 opt: 4729 Z-score: 3879.1 bits: 728.6 E(85289): 2.5e-209 Smith-Waterman score: 4729; 100.0% identity (100.0% similar) in 713 aa overlap (173-885:1-713) 150 160 170 180 190 200 pF1KB4 RFKKDEHLEKAFKCLTSGEWARHYFLNKNKMQEKLFKEHVFIYLRMFATDSGFEILPCNR :::::::::::::::::::::::::::::: XP_016 MQEKLFKEHVFIYLRMFATDSGFEILPCNR 10 20 30 210 220 230 240 250 260 pF1KB4 YSSEQNGAKIVATKEWKRNDKIELLVGCIAELSEIEENMLLRHGENDFSVMYSTRKNCAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YSSEQNGAKIVATKEWKRNDKIELLVGCIAELSEIEENMLLRHGENDFSVMYSTRKNCAQ 40 50 60 70 80 90 270 280 290 300 310 320 pF1KB4 LWLGPAAFINHDCRPNCKFVSTGRDTACVKALRDIEPGEEISCYYGDGFFGENNEFCECY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LWLGPAAFINHDCRPNCKFVSTGRDTACVKALRDIEPGEEISCYYGDGFFGENNEFCECY 100 110 120 130 140 150 330 340 350 360 370 380 pF1KB4 TCERRGTGAFKSRVGLPAPAPVINSKYGLRETDKRLNRLKKLGDSSKNSDSQSVSSNTDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TCERRGTGAFKSRVGLPAPAPVINSKYGLRETDKRLNRLKKLGDSSKNSDSQSVSSNTDA 160 170 180 190 200 210 390 400 410 420 430 440 pF1KB4 DTTQEKNNATSNRKSSVGVKKNSKSRTLTRQSMSRIPASSNSTSSKLTHINNSRVPKKLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DTTQEKNNATSNRKSSVGVKKNSKSRTLTRQSMSRIPASSNSTSSKLTHINNSRVPKKLK 220 230 240 250 260 270 450 460 470 480 490 500 pF1KB4 KPAKPLLSKIKLRNHCKRLEQKNASRKLEMGNLVLKEPKVVLYKNLPIKKDKEPEGPAQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KPAKPLLSKIKLRNHCKRLEQKNASRKLEMGNLVLKEPKVVLYKNLPIKKDKEPEGPAQA 280 290 300 310 320 330 510 520 530 540 550 560 pF1KB4 AVASGCLTRHAAREHRQNPVRGAHSQGESSPCTYITRRSVRTRTNLKEASDIKLEPNTLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AVASGCLTRHAAREHRQNPVRGAHSQGESSPCTYITRRSVRTRTNLKEASDIKLEPNTLN 340 350 360 370 380 390 570 580 590 600 610 620 pF1KB4 GYKSSVTEPCPDSGEQLQPAPVLQEEELAHETAQKGEAKCHKSDTGMSKKKSRQGKLVKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GYKSSVTEPCPDSGEQLQPAPVLQEEELAHETAQKGEAKCHKSDTGMSKKKSRQGKLVKQ 400 410 420 430 440 450 630 640 650 660 670 680 pF1KB4 FAKIEESTPVHDSPGKDDAVPDLMGPHSDQGEHSGTVGVPVSYTDCAPSPVGCSVVTSDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FAKIEESTPVHDSPGKDDAVPDLMGPHSDQGEHSGTVGVPVSYTDCAPSPVGCSVVTSDS 460 470 480 490 500 510 690 700 710 720 730 740 pF1KB4 FKTKDSFRTAKSKKKRRITRYDAQLILENNSGIPKLTLRRRHDSSSKTNDQENDGMNSSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FKTKDSFRTAKSKKKRRITRYDAQLILENNSGIPKLTLRRRHDSSSKTNDQENDGMNSSK 520 530 540 550 560 570 750 760 770 780 790 800 pF1KB4 ISIKLSKDHDNDNNLYVAKLNNGFNSGSGSSSTKLKIQLKRDEENRGSYTEGLHENGVCC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ISIKLSKDHDNDNNLYVAKLNNGFNSGSGSSSTKLKIQLKRDEENRGSYTEGLHENGVCC 580 590 600 610 620 630 810 820 830 840 850 860 pF1KB4 SDPLSLLESRMEVDDYSQYEEESTDDSSSSEGDEEEDDYDDDFEDDFIPLPPAKRLRLIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SDPLSLLESRMEVDDYSQYEEESTDDSSSSEGDEEEDDYDDDFEDDFIPLPPAKRLRLIV 640 650 660 670 680 690 870 880 pF1KB4 GKDSIDIDISSRRREDQSLRLNA ::::::::::::::::::::::: XP_016 GKDSIDIDISSRRREDQSLRLNA 700 710 885 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 15:11:07 2016 done: Thu Nov 3 15:11:09 2016 Total Scan time: 14.260 Total Display time: 0.330 Function used was FASTA [36.3.4 Apr, 2011]