FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB4604, 303 aa 1>>>pF1KB4604 303 - 303 aa - 303 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.6392+/-0.000366; mu= 14.6345+/- 0.023 mean_var=88.9598+/-18.172, 0's: 0 Z-trim(115.9): 52 B-trim: 815 in 2/52 Lambda= 0.135981 statistics sampled from 26578 (26632) to 26578 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.694), E-opt: 0.2 (0.312), width: 16 Scan time: 7.590 The best scores are: opt bits E(85289) NP_003109 (OMIM: 182120,616507) SPARC isoform 1 pr ( 303) 2131 427.9 1.2e-119 NP_001296372 (OMIM: 182120,616507) SPARC isoform 2 ( 302) 2112 424.1 1.6e-118 NP_001296373 (OMIM: 182120,616507) SPARC isoform 3 ( 341) 2078 417.5 1.8e-116 NP_001278906 (OMIM: 606041) SPARC-like protein 1 i ( 539) 1110 227.8 3.8e-59 NP_001278905 (OMIM: 606041) SPARC-like protein 1 i ( 539) 1110 227.8 3.8e-59 NP_001121782 (OMIM: 606041) SPARC-like protein 1 i ( 664) 1110 227.8 4.5e-59 NP_004675 (OMIM: 606041) SPARC-like protein 1 isof ( 664) 1110 227.8 4.5e-59 NP_006341 (OMIM: 136470) follistatin isoform FST31 ( 317) 180 45.1 0.00021 NP_037541 (OMIM: 136470) follistatin isoform FST34 ( 344) 180 45.2 0.00023 NP_001191281 (OMIM: 607989) testican-3 isoform 3 [ ( 385) 175 44.2 0.00049 XP_016863747 (OMIM: 607989) PREDICTED: testican-3 ( 433) 175 44.3 0.00053 NP_001035249 (OMIM: 607989) testican-3 isoform 1 p ( 433) 175 44.3 0.00053 XP_011530320 (OMIM: 607989) PREDICTED: testican-3 ( 436) 175 44.3 0.00053 NP_058646 (OMIM: 607989) testican-3 isoform 2 prec ( 436) 175 44.3 0.00053 XP_016863746 (OMIM: 607989) PREDICTED: testican-3 ( 445) 175 44.3 0.00054 NP_001191287 (OMIM: 607989) testican-3 isoform 9 p ( 313) 172 43.6 0.00062 XP_005248460 (OMIM: 136470) PREDICTED: follistatin ( 316) 172 43.6 0.00063 XP_005248458 (OMIM: 136470) PREDICTED: follistatin ( 343) 172 43.6 0.00067 XP_011538706 (OMIM: 607988) PREDICTED: testican-2 ( 421) 173 43.9 0.00068 NP_001231879 (OMIM: 607988) testican-2 isoform 2 p ( 424) 173 43.9 0.00069 NP_055582 (OMIM: 607988) testican-2 isoform 2 prec ( 424) 173 43.9 0.00069 XP_016864444 (OMIM: 136470) PREDICTED: follistatin ( 279) 168 42.7 0.00098 NP_001159884 (OMIM: 125400,607223) SPARC-related m ( 446) 170 43.3 0.0011 NP_071421 (OMIM: 125400,607223) SPARC-related modu ( 457) 170 43.3 0.0011 XP_011534368 (OMIM: 125400,607223) PREDICTED: SPAR ( 464) 170 43.3 0.0011 XP_005248459 (OMIM: 136470) PREDICTED: follistatin ( 330) 168 42.8 0.0011 XP_011534367 (OMIM: 125400,607223) PREDICTED: SPAR ( 475) 170 43.3 0.0011 XP_016864443 (OMIM: 136470) PREDICTED: follistatin ( 337) 168 42.8 0.0011 XP_011541401 (OMIM: 136470) PREDICTED: follistatin ( 352) 168 42.8 0.0012 XP_005248457 (OMIM: 136470) PREDICTED: follistatin ( 357) 168 42.8 0.0012 NP_005851 (OMIM: 605343) follistatin-related prote ( 263) 166 42.3 0.0012 NP_071420 (OMIM: 206920,608488) SPARC-related modu ( 434) 159 41.1 0.0047 NP_001030024 (OMIM: 206920,608488) SPARC-related m ( 435) 159 41.1 0.0047 XP_005268053 (OMIM: 206920,608488) PREDICTED: SPAR ( 445) 159 41.1 0.0048 XP_005268052 (OMIM: 206920,608488) PREDICTED: SPAR ( 446) 159 41.1 0.0048 NP_001191285 (OMIM: 607989) testican-3 isoform 7 p ( 393) 158 40.9 0.005 >>NP_003109 (OMIM: 182120,616507) SPARC isoform 1 precur (303 aa) initn: 2131 init1: 2131 opt: 2131 Z-score: 2268.8 bits: 427.9 E(85289): 1.2e-119 Smith-Waterman score: 2131; 100.0% identity (100.0% similar) in 303 aa overlap (1-303:1-303) 10 20 30 40 50 60 pF1KB4 MRAWIFFLLCLAGRALAAPQQEALPDETEVVEETVAEVTEVSVGANPVQVEVGEFDDGAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 MRAWIFFLLCLAGRALAAPQQEALPDETEVVEETVAEVTEVSVGANPVQVEVGEFDDGAE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 ETEEEVVAENPCQNHHCKHGKVCELDENNTPMCVCQDPTSCPAPIGEFEKVCSNDNKTFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 ETEEEVVAENPCQNHHCKHGKVCELDENNTPMCVCQDPTSCPAPIGEFEKVCSNDNKTFD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 SSCHFFATKCTLEGTKKGHKLHLDYIGPCKYIPPCLDSELTEFPLRMRDWLKNVLVTLYE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 SSCHFFATKCTLEGTKKGHKLHLDYIGPCKYIPPCLDSELTEFPLRMRDWLKNVLVTLYE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 RDEDNNLLTEKQKLRVKKIHENEKRLEAGDHPVELLARDFEKNYNMYIFPVHWQFGQLDQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 RDEDNNLLTEKQKLRVKKIHENEKRLEAGDHPVELLARDFEKNYNMYIFPVHWQFGQLDQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 HPIDGYLSHTELAPLRAPLIPMEHCTTRFFETCDLDNDKYIALDEWAGCFGIKQKDIDKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 HPIDGYLSHTELAPLRAPLIPMEHCTTRFFETCDLDNDKYIALDEWAGCFGIKQKDIDKD 250 260 270 280 290 300 pF1KB4 LVI ::: NP_003 LVI >>NP_001296372 (OMIM: 182120,616507) SPARC isoform 2 pre (302 aa) initn: 1994 init1: 1994 opt: 2112 Z-score: 2248.6 bits: 424.1 E(85289): 1.6e-118 Smith-Waterman score: 2112; 99.7% identity (99.7% similar) in 303 aa overlap (1-303:1-302) 10 20 30 40 50 60 pF1KB4 MRAWIFFLLCLAGRALAAPQQEALPDETEVVEETVAEVTEVSVGANPVQVEVGEFDDGAE :::::::::::::::::::: ::::::::::::::::::::::::::::::::::::::: NP_001 MRAWIFFLLCLAGRALAAPQ-EALPDETEVVEETVAEVTEVSVGANPVQVEVGEFDDGAE 10 20 30 40 50 70 80 90 100 110 120 pF1KB4 ETEEEVVAENPCQNHHCKHGKVCELDENNTPMCVCQDPTSCPAPIGEFEKVCSNDNKTFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ETEEEVVAENPCQNHHCKHGKVCELDENNTPMCVCQDPTSCPAPIGEFEKVCSNDNKTFD 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB4 SSCHFFATKCTLEGTKKGHKLHLDYIGPCKYIPPCLDSELTEFPLRMRDWLKNVLVTLYE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSCHFFATKCTLEGTKKGHKLHLDYIGPCKYIPPCLDSELTEFPLRMRDWLKNVLVTLYE 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB4 RDEDNNLLTEKQKLRVKKIHENEKRLEAGDHPVELLARDFEKNYNMYIFPVHWQFGQLDQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RDEDNNLLTEKQKLRVKKIHENEKRLEAGDHPVELLARDFEKNYNMYIFPVHWQFGQLDQ 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB4 HPIDGYLSHTELAPLRAPLIPMEHCTTRFFETCDLDNDKYIALDEWAGCFGIKQKDIDKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HPIDGYLSHTELAPLRAPLIPMEHCTTRFFETCDLDNDKYIALDEWAGCFGIKQKDIDKD 240 250 260 270 280 290 pF1KB4 LVI ::: NP_001 LVI 300 >>NP_001296373 (OMIM: 182120,616507) SPARC isoform 3 pre (341 aa) initn: 2098 init1: 2078 opt: 2078 Z-score: 2211.9 bits: 417.5 E(85289): 1.8e-116 Smith-Waterman score: 2078; 99.7% identity (100.0% similar) in 295 aa overlap (1-295:1-295) 10 20 30 40 50 60 pF1KB4 MRAWIFFLLCLAGRALAAPQQEALPDETEVVEETVAEVTEVSVGANPVQVEVGEFDDGAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MRAWIFFLLCLAGRALAAPQQEALPDETEVVEETVAEVTEVSVGANPVQVEVGEFDDGAE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 ETEEEVVAENPCQNHHCKHGKVCELDENNTPMCVCQDPTSCPAPIGEFEKVCSNDNKTFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ETEEEVVAENPCQNHHCKHGKVCELDENNTPMCVCQDPTSCPAPIGEFEKVCSNDNKTFD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 SSCHFFATKCTLEGTKKGHKLHLDYIGPCKYIPPCLDSELTEFPLRMRDWLKNVLVTLYE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSCHFFATKCTLEGTKKGHKLHLDYIGPCKYIPPCLDSELTEFPLRMRDWLKNVLVTLYE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 RDEDNNLLTEKQKLRVKKIHENEKRLEAGDHPVELLARDFEKNYNMYIFPVHWQFGQLDQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RDEDNNLLTEKQKLRVKKIHENEKRLEAGDHPVELLARDFEKNYNMYIFPVHWQFGQLDQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 HPIDGYLSHTELAPLRAPLIPMEHCTTRFFETCDLDNDKYIALDEWAGCFGIKQKDIDKD ::::::::::::::::::::::::::::::::::::::::::::::::::::::. NP_001 HPIDGYLSHTELAPLRAPLIPMEHCTTRFFETCDLDNDKYIALDEWAGCFGIKQRYRQGS 250 260 270 280 290 300 pF1KB4 LVI NP_001 CDLNPLLPQYRILSLTLPFVFPPMFKMFGWFVVLPGDKVLT 310 320 330 340 >>NP_001278906 (OMIM: 606041) SPARC-like protein 1 isofo (539 aa) initn: 971 init1: 612 opt: 1110 Z-score: 1182.8 bits: 227.8 E(85289): 3.8e-59 Smith-Waterman score: 1110; 52.7% identity (78.0% similar) in 296 aa overlap (12-302:246-538) 10 20 30 40 pF1KB4 MRAWIFFLLCLAGRALAAPQQEALPDETEVVEETVAEVTEV : :: . . . .. : :.:. .. . NP_001 GDDDGDDGGTDGPRHSASDDYFIPSQAFLEAERAQSIAYHLKIEEQREKVHEN-ENIGTT 220 230 240 250 260 270 50 60 70 80 90 pF1KB4 SVGANPVQVEVGEFDDGAEETEEE----VVAENPCQNHHCKHGKVCELDENNTPMCVCQD : . ... .: ... ::: : : : . :.. .::.:..:. :... : ::::: NP_001 EPGEHQ-EAKKAENSSNEEETSSEGNMRVHAVDSCMSFQCKRGHICKADQQGKPHCVCQD 280 290 300 310 320 330 100 110 120 130 140 150 pF1KB4 PTSCPAPIGEFEKVCSNDNKTFDSSCHFFATKCTLEGTKKGHKLHLDYIGPCKYIPPCLD :..:: : ...::..::.:. ::::.::::: ::::::::.:.:::.: :: :: : : NP_001 PVTCP-PTKPLDQVCGTDNQTYASSCHLFATKCRLEGTKKGHQLQLDYFGACKSIPTCTD 340 350 360 370 380 390 160 170 180 190 200 210 pF1KB4 SELTEFPLRMRDWLKNVLVTLYERD-EDNNLLTEKQKLRVKKIHENEKRLEAGDHPVELL :. .:::::::::::.:. ::: . : . :.:::. .::::. .:::: :::::..:: NP_001 FEVIQFPLRMRDWLKNILMQLYEANSEHAGYLNEKQRNKVKKIYLDEKRLLAGDHPIDLL 400 410 420 430 440 450 220 230 240 250 260 270 pF1KB4 ARDFEKNYNMYIFPVHWQFGQLDQHPIDGYLSHTELAPLRAPLIPMEHCTTRFFETCDLD :::.:::.::..::::::..:::::.: :.:.::::::: :.::::: ::::: :: . NP_001 LRDFKKNYHMYVYPVHWQFSELDQHPMDRVLTHSELAPLRASLVPMEHCITRFFEECDPN 460 470 480 490 500 510 280 290 300 pF1KB4 NDKYIALDEWAGCFGIKQKDIDKDLVI .::.:.: ::. :::::..:::..:. NP_001 KDKHITLKEWGHCFGIKEEDIDENLLF 520 530 >>NP_001278905 (OMIM: 606041) SPARC-like protein 1 isofo (539 aa) initn: 971 init1: 612 opt: 1110 Z-score: 1182.8 bits: 227.8 E(85289): 3.8e-59 Smith-Waterman score: 1110; 52.7% identity (78.0% similar) in 296 aa overlap (12-302:246-538) 10 20 30 40 pF1KB4 MRAWIFFLLCLAGRALAAPQQEALPDETEVVEETVAEVTEV : :: . . . .. : :.:. .. . NP_001 GDDDGDDGGTDGPRHSASDDYFIPSQAFLEAERAQSIAYHLKIEEQREKVHEN-ENIGTT 220 230 240 250 260 270 50 60 70 80 90 pF1KB4 SVGANPVQVEVGEFDDGAEETEEE----VVAENPCQNHHCKHGKVCELDENNTPMCVCQD : . ... .: ... ::: : : : . :.. .::.:..:. :... : ::::: NP_001 EPGEHQ-EAKKAENSSNEEETSSEGNMRVHAVDSCMSFQCKRGHICKADQQGKPHCVCQD 280 290 300 310 320 330 100 110 120 130 140 150 pF1KB4 PTSCPAPIGEFEKVCSNDNKTFDSSCHFFATKCTLEGTKKGHKLHLDYIGPCKYIPPCLD :..:: : ...::..::.:. ::::.::::: ::::::::.:.:::.: :: :: : : NP_001 PVTCP-PTKPLDQVCGTDNQTYASSCHLFATKCRLEGTKKGHQLQLDYFGACKSIPTCTD 340 350 360 370 380 390 160 170 180 190 200 210 pF1KB4 SELTEFPLRMRDWLKNVLVTLYERD-EDNNLLTEKQKLRVKKIHENEKRLEAGDHPVELL :. .:::::::::::.:. ::: . : . :.:::. .::::. .:::: :::::..:: NP_001 FEVIQFPLRMRDWLKNILMQLYEANSEHAGYLNEKQRNKVKKIYLDEKRLLAGDHPIDLL 400 410 420 430 440 450 220 230 240 250 260 270 pF1KB4 ARDFEKNYNMYIFPVHWQFGQLDQHPIDGYLSHTELAPLRAPLIPMEHCTTRFFETCDLD :::.:::.::..::::::..:::::.: :.:.::::::: :.::::: ::::: :: . NP_001 LRDFKKNYHMYVYPVHWQFSELDQHPMDRVLTHSELAPLRASLVPMEHCITRFFEECDPN 460 470 480 490 500 510 280 290 300 pF1KB4 NDKYIALDEWAGCFGIKQKDIDKDLVI .::.:.: ::. :::::..:::..:. NP_001 KDKHITLKEWGHCFGIKEEDIDENLLF 520 530 >>NP_001121782 (OMIM: 606041) SPARC-like protein 1 isofo (664 aa) initn: 1002 init1: 612 opt: 1110 Z-score: 1181.6 bits: 227.8 E(85289): 4.5e-59 Smith-Waterman score: 1110; 52.7% identity (78.0% similar) in 296 aa overlap (12-302:371-663) 10 20 30 40 pF1KB4 MRAWIFFLLCLAGRALAAPQQEALPDETEVVEETVAEVTEV : :: . . . .. : :.:. .. . NP_001 GDDDGDDGGTDGPRHSASDDYFIPSQAFLEAERAQSIAYHLKIEEQREKVHEN-ENIGTT 350 360 370 380 390 50 60 70 80 90 pF1KB4 SVGANPVQVEVGEFDDGAEETEEE----VVAENPCQNHHCKHGKVCELDENNTPMCVCQD : . ... .: ... ::: : : : . :.. .::.:..:. :... : ::::: NP_001 EPGEHQ-EAKKAENSSNEEETSSEGNMRVHAVDSCMSFQCKRGHICKADQQGKPHCVCQD 400 410 420 430 440 450 100 110 120 130 140 150 pF1KB4 PTSCPAPIGEFEKVCSNDNKTFDSSCHFFATKCTLEGTKKGHKLHLDYIGPCKYIPPCLD :..:: : ...::..::.:. ::::.::::: ::::::::.:.:::.: :: :: : : NP_001 PVTCP-PTKPLDQVCGTDNQTYASSCHLFATKCRLEGTKKGHQLQLDYFGACKSIPTCTD 460 470 480 490 500 510 160 170 180 190 200 210 pF1KB4 SELTEFPLRMRDWLKNVLVTLYERD-EDNNLLTEKQKLRVKKIHENEKRLEAGDHPVELL :. .:::::::::::.:. ::: . : . :.:::. .::::. .:::: :::::..:: NP_001 FEVIQFPLRMRDWLKNILMQLYEANSEHAGYLNEKQRNKVKKIYLDEKRLLAGDHPIDLL 520 530 540 550 560 570 220 230 240 250 260 270 pF1KB4 ARDFEKNYNMYIFPVHWQFGQLDQHPIDGYLSHTELAPLRAPLIPMEHCTTRFFETCDLD :::.:::.::..::::::..:::::.: :.:.::::::: :.::::: ::::: :: . NP_001 LRDFKKNYHMYVYPVHWQFSELDQHPMDRVLTHSELAPLRASLVPMEHCITRFFEECDPN 580 590 600 610 620 630 280 290 300 pF1KB4 NDKYIALDEWAGCFGIKQKDIDKDLVI .::.:.: ::. :::::..:::..:. NP_001 KDKHITLKEWGHCFGIKEEDIDENLLF 640 650 660 >>NP_004675 (OMIM: 606041) SPARC-like protein 1 isoform (664 aa) initn: 1002 init1: 612 opt: 1110 Z-score: 1181.6 bits: 227.8 E(85289): 4.5e-59 Smith-Waterman score: 1110; 52.7% identity (78.0% similar) in 296 aa overlap (12-302:371-663) 10 20 30 40 pF1KB4 MRAWIFFLLCLAGRALAAPQQEALPDETEVVEETVAEVTEV : :: . . . .. : :.:. .. . NP_004 GDDDGDDGGTDGPRHSASDDYFIPSQAFLEAERAQSIAYHLKIEEQREKVHEN-ENIGTT 350 360 370 380 390 50 60 70 80 90 pF1KB4 SVGANPVQVEVGEFDDGAEETEEE----VVAENPCQNHHCKHGKVCELDENNTPMCVCQD : . ... .: ... ::: : : : . :.. .::.:..:. :... : ::::: NP_004 EPGEHQ-EAKKAENSSNEEETSSEGNMRVHAVDSCMSFQCKRGHICKADQQGKPHCVCQD 400 410 420 430 440 450 100 110 120 130 140 150 pF1KB4 PTSCPAPIGEFEKVCSNDNKTFDSSCHFFATKCTLEGTKKGHKLHLDYIGPCKYIPPCLD :..:: : ...::..::.:. ::::.::::: ::::::::.:.:::.: :: :: : : NP_004 PVTCP-PTKPLDQVCGTDNQTYASSCHLFATKCRLEGTKKGHQLQLDYFGACKSIPTCTD 460 470 480 490 500 510 160 170 180 190 200 210 pF1KB4 SELTEFPLRMRDWLKNVLVTLYERD-EDNNLLTEKQKLRVKKIHENEKRLEAGDHPVELL :. .:::::::::::.:. ::: . : . :.:::. .::::. .:::: :::::..:: NP_004 FEVIQFPLRMRDWLKNILMQLYEANSEHAGYLNEKQRNKVKKIYLDEKRLLAGDHPIDLL 520 530 540 550 560 570 220 230 240 250 260 270 pF1KB4 ARDFEKNYNMYIFPVHWQFGQLDQHPIDGYLSHTELAPLRAPLIPMEHCTTRFFETCDLD :::.:::.::..::::::..:::::.: :.:.::::::: :.::::: ::::: :: . NP_004 LRDFKKNYHMYVYPVHWQFSELDQHPMDRVLTHSELAPLRASLVPMEHCITRFFEECDPN 580 590 600 610 620 630 280 290 300 pF1KB4 NDKYIALDEWAGCFGIKQKDIDKDLVI .::.:.: ::. :::::..:::..:. NP_004 KDKHITLKEWGHCFGIKEEDIDENLLF 640 650 660 >>NP_006341 (OMIM: 136470) follistatin isoform FST317 pr (317 aa) initn: 203 init1: 92 opt: 180 Z-score: 200.0 bits: 45.1 E(85289): 0.00021 Smith-Waterman score: 180; 30.8% identity (58.2% similar) in 91 aa overlap (72-161:168-251) 50 60 70 80 90 100 pF1KB4 SVGANPVQVEVGEFDDGAEETEEEVVAENPCQNHHCKHGKVCELDENNTPMCV-CQDPTS :.. : ...: .:..:. .:: :. NP_006 TYRNECALLKARCKEQPELEVQYQGRCKKTCRDVFCPGSSTCVVDQTNNAYCVTCN--RI 140 150 160 170 180 190 110 120 130 140 150 160 pF1KB4 CPAPIGEFEKVCSNDNKTFDSSCHFFATKCTLEGTKKGHKLHLDYIGPCKYIPPCLDSEL :: : . . .:.::. :..:.::. . : : :... : : : : : : . NP_006 CPEPASSEQYLCGNDGVTYSSACHLRKATCLL-----GRSIGLAYEGKCIKAKSCEDIQC 200 210 220 230 240 250 170 180 190 200 210 220 pF1KB4 TEFPLRMRDWLKNVLVTLYERDEDNNLLTEKQKLRVKKIHENEKRLEAGDHPVELLARDF : NP_006 TGGKKCLWDFKVGRGRCSLCDELCPDSKSDEPVCASDNATYASECAMKEAACSSGVLLEV 260 270 280 290 300 310 >>NP_037541 (OMIM: 136470) follistatin isoform FST344 pr (344 aa) initn: 203 init1: 92 opt: 180 Z-score: 199.5 bits: 45.2 E(85289): 0.00023 Smith-Waterman score: 180; 30.8% identity (58.2% similar) in 91 aa overlap (72-161:168-251) 50 60 70 80 90 100 pF1KB4 SVGANPVQVEVGEFDDGAEETEEEVVAENPCQNHHCKHGKVCELDENNTPMCV-CQDPTS :.. : ...: .:..:. .:: :. NP_037 TYRNECALLKARCKEQPELEVQYQGRCKKTCRDVFCPGSSTCVVDQTNNAYCVTCN--RI 140 150 160 170 180 190 110 120 130 140 150 160 pF1KB4 CPAPIGEFEKVCSNDNKTFDSSCHFFATKCTLEGTKKGHKLHLDYIGPCKYIPPCLDSEL :: : . . .:.::. :..:.::. . : : :... : : : : : : . NP_037 CPEPASSEQYLCGNDGVTYSSACHLRKATCLL-----GRSIGLAYEGKCIKAKSCEDIQC 200 210 220 230 240 250 170 180 190 200 210 220 pF1KB4 TEFPLRMRDWLKNVLVTLYERDEDNNLLTEKQKLRVKKIHENEKRLEAGDHPVELLARDF : NP_037 TGGKKCLWDFKVGRGRCSLCDELCPDSKSDEPVCASDNATYASECAMKEAACSSGVLLEV 260 270 280 290 300 310 >>NP_001191281 (OMIM: 607989) testican-3 isoform 3 [Homo (385 aa) initn: 188 init1: 106 opt: 175 Z-score: 193.5 bits: 44.2 E(85289): 0.00049 Smith-Waterman score: 232; 25.2% identity (49.6% similar) in 262 aa overlap (68-296:35-263) 40 50 60 70 80 90 pF1KB4 VTEVSVGANPVQVEVGEFDDGAEETEEEVVAENPCQNHHCKHGKVCELDENNTPMCVCQ- :..:: . .:.. ::: ....: .:. . NP_001 DHIHMSSGLSQDDYFRTWSPGKPFDQALDPAKDPCLKMKCSRHKVCIAQDSQTAVCISHR 10 20 30 40 50 60 100 110 120 130 pF1KB4 -----------------DP--TSCPA-PIGEFEKVCSNDNKTFDSSCHFFATKCTLEGTK : ..: :. ::..:..:.. .:.. :.: NP_001 RLTHRMKEAGVDHRQWRGPILSTCKQCPVVYPSPVCGSDGHTYSFQCKLEYQACVL---- 70 80 90 100 110 120 140 150 160 170 180 pF1KB4 KGHKLHLDYIG--PCKYIPP----------CLDSELTEFPLRMRDWLKNVLVTLYERDED :... . : :: : : : :. : :.:::.: .:.: . NP_001 -GKQISVKCEGHCPCPSDKPTSTSRNVKRACSDLEFREVANRLRDWFK----ALHESGSQ 130 140 150 160 170 190 200 210 220 230 240 pF1KB4 NNLLTEKQKLRVKKIHENEKRLEAGDHPVELLARDFEKNYNMYIFPVHWQFGQLDQHPID :. : :: .. .:.... :. .: . :.:..:: . : NP_001 NK--KTKTLLRPER-----SRFDTSILPI---CKD----------SLGWMFNRLDTN-YD 180 190 200 210 250 260 270 280 290 300 pF1KB4 GYLSHTELAPLRAPLIPMEHCTTRFFETCDLDNDKYIALDEWAGCFGIKQKDIDKDLVI :...:: . : :.:: ::..:: .:. :. .:: :: .:.: NP_001 LLLDQSELRSIY--LDKNEQCTKAFFNSCDTYKDSLISNNEWCYCFQ-RQQDPPCQTELS 220 230 240 250 260 270 NP_001 NIQKRQGVKKLLGQYIPLCDEDGYYKPTQCHGSVGQCWCVDRYGNEVMGSRINGVADCAI 280 290 300 310 320 330 303 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 03:04:07 2016 done: Fri Nov 4 03:04:08 2016 Total Scan time: 7.590 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]