FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB4606, 123 aa 1>>>pF1KB4606 123 - 123 aa - 123 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.9203+/-0.00038; mu= 12.0898+/- 0.024 mean_var=51.1201+/-10.144, 0's: 0 Z-trim(111.5): 32 B-trim: 161 in 1/50 Lambda= 0.179382 statistics sampled from 20137 (20164) to 20137 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.612), E-opt: 0.2 (0.236), width: 16 Scan time: 4.300 The best scores are: opt bits E(85289) NP_751951 (OMIM: 603796,611493,613693) potassium v ( 123) 793 212.8 1.2e-55 NP_001257331 (OMIM: 176261,612347,613695) potassiu ( 129) 169 51.3 4.9e-07 NP_001121141 (OMIM: 176261,612347,613695) potassiu ( 129) 169 51.3 4.9e-07 NP_001121140 (OMIM: 176261,612347,613695) potassiu ( 129) 169 51.3 4.9e-07 NP_001257332 (OMIM: 176261,612347,613695) potassiu ( 129) 169 51.3 4.9e-07 NP_001121142 (OMIM: 176261,612347,613695) potassiu ( 129) 169 51.3 4.9e-07 NP_001257333 (OMIM: 176261,612347,613695) potassiu ( 129) 169 51.3 4.9e-07 NP_000210 (OMIM: 176261,612347,613695) potassium v ( 129) 169 51.3 4.9e-07 NP_001257334 (OMIM: 176261,612347,613695) potassiu ( 129) 169 51.3 4.9e-07 XP_016883831 (OMIM: 176261,612347,613695) PREDICTE ( 150) 169 51.3 5.6e-07 >>NP_751951 (OMIM: 603796,611493,613693) potassium volta (123 aa) initn: 793 init1: 793 opt: 793 Z-score: 1120.3 bits: 212.8 E(85289): 1.2e-55 Smith-Waterman score: 793; 100.0% identity (100.0% similar) in 123 aa overlap (1-123:1-123) 10 20 30 40 50 60 pF1KB4 MSTLSNFTQTLEDVFRRIFITYMDNWRQNTTAEQEALQAKVDAENFYYVILYLMVMIGMF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_751 MSTLSNFTQTLEDVFRRIFITYMDNWRQNTTAEQEALQAKVDAENFYYVILYLMVMIGMF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 SFIIVAILVSTVKSKRREHSNDPYHQYIVEDWQEKYKSQILNLEESKATIHENIGAAGFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_751 SFIIVAILVSTVKSKRREHSNDPYHQYIVEDWQEKYKSQILNLEESKATIHENIGAAGFK 70 80 90 100 110 120 pF1KB4 MSP ::: NP_751 MSP >>NP_001257331 (OMIM: 176261,612347,613695) potassium vo (129 aa) initn: 167 init1: 140 opt: 169 Z-score: 247.3 bits: 51.3 E(85289): 4.9e-07 Smith-Waterman score: 169; 45.1% identity (82.4% similar) in 51 aa overlap (51-100:45-95) 30 40 50 60 70 80 pF1KB4 TYMDNWRQNTTAEQEALQAKVDAENFYYVILYLMVMIGMFSFIIVAILVSTVKSKRREHS ::.....:.:.:. ..:..: ..::. ::: NP_001 KLWQETVQQGGNMSGLARRSPRSSDGKLEALYVLMVLGFFGFFTLGIMLSYIRSKKLEHS 20 30 40 50 60 70 90 100 110 120 pF1KB4 NDPYHQYIVED-WQEKYKSQILNLEESKATIHENIGAAGFKMSP :::.. :: : :::: :. . NP_001 NDPFNVYIESDAWQEKDKAYVQARVLESYRSCYVVENHLAIEQPNTHLPETKPSP 80 90 100 110 120 >>NP_001121141 (OMIM: 176261,612347,613695) potassium vo (129 aa) initn: 167 init1: 140 opt: 169 Z-score: 247.3 bits: 51.3 E(85289): 4.9e-07 Smith-Waterman score: 169; 45.1% identity (82.4% similar) in 51 aa overlap (51-100:45-95) 30 40 50 60 70 80 pF1KB4 TYMDNWRQNTTAEQEALQAKVDAENFYYVILYLMVMIGMFSFIIVAILVSTVKSKRREHS ::.....:.:.:. ..:..: ..::. ::: NP_001 KLWQETVQQGGNMSGLARRSPRSSDGKLEALYVLMVLGFFGFFTLGIMLSYIRSKKLEHS 20 30 40 50 60 70 90 100 110 120 pF1KB4 NDPYHQYIVED-WQEKYKSQILNLEESKATIHENIGAAGFKMSP :::.. :: : :::: :. . NP_001 NDPFNVYIESDAWQEKDKAYVQARVLESYRSCYVVENHLAIEQPNTHLPETKPSP 80 90 100 110 120 >>NP_001121140 (OMIM: 176261,612347,613695) potassium vo (129 aa) initn: 167 init1: 140 opt: 169 Z-score: 247.3 bits: 51.3 E(85289): 4.9e-07 Smith-Waterman score: 169; 45.1% identity (82.4% similar) in 51 aa overlap (51-100:45-95) 30 40 50 60 70 80 pF1KB4 TYMDNWRQNTTAEQEALQAKVDAENFYYVILYLMVMIGMFSFIIVAILVSTVKSKRREHS ::.....:.:.:. ..:..: ..::. ::: NP_001 KLWQETVQQGGNMSGLARRSPRSSDGKLEALYVLMVLGFFGFFTLGIMLSYIRSKKLEHS 20 30 40 50 60 70 90 100 110 120 pF1KB4 NDPYHQYIVED-WQEKYKSQILNLEESKATIHENIGAAGFKMSP :::.. :: : :::: :. . NP_001 NDPFNVYIESDAWQEKDKAYVQARVLESYRSCYVVENHLAIEQPNTHLPETKPSP 80 90 100 110 120 >>NP_001257332 (OMIM: 176261,612347,613695) potassium vo (129 aa) initn: 167 init1: 140 opt: 169 Z-score: 247.3 bits: 51.3 E(85289): 4.9e-07 Smith-Waterman score: 169; 45.1% identity (82.4% similar) in 51 aa overlap (51-100:45-95) 30 40 50 60 70 80 pF1KB4 TYMDNWRQNTTAEQEALQAKVDAENFYYVILYLMVMIGMFSFIIVAILVSTVKSKRREHS ::.....:.:.:. ..:..: ..::. ::: NP_001 KLWQETVQQGGNMSGLARRSPRSSDGKLEALYVLMVLGFFGFFTLGIMLSYIRSKKLEHS 20 30 40 50 60 70 90 100 110 120 pF1KB4 NDPYHQYIVED-WQEKYKSQILNLEESKATIHENIGAAGFKMSP :::.. :: : :::: :. . NP_001 NDPFNVYIESDAWQEKDKAYVQARVLESYRSCYVVENHLAIEQPNTHLPETKPSP 80 90 100 110 120 >>NP_001121142 (OMIM: 176261,612347,613695) potassium vo (129 aa) initn: 167 init1: 140 opt: 169 Z-score: 247.3 bits: 51.3 E(85289): 4.9e-07 Smith-Waterman score: 169; 45.1% identity (82.4% similar) in 51 aa overlap (51-100:45-95) 30 40 50 60 70 80 pF1KB4 TYMDNWRQNTTAEQEALQAKVDAENFYYVILYLMVMIGMFSFIIVAILVSTVKSKRREHS ::.....:.:.:. ..:..: ..::. ::: NP_001 KLWQETVQQGGNMSGLARRSPRSSDGKLEALYVLMVLGFFGFFTLGIMLSYIRSKKLEHS 20 30 40 50 60 70 90 100 110 120 pF1KB4 NDPYHQYIVED-WQEKYKSQILNLEESKATIHENIGAAGFKMSP :::.. :: : :::: :. . NP_001 NDPFNVYIESDAWQEKDKAYVQARVLESYRSCYVVENHLAIEQPNTHLPETKPSP 80 90 100 110 120 >>NP_001257333 (OMIM: 176261,612347,613695) potassium vo (129 aa) initn: 167 init1: 140 opt: 169 Z-score: 247.3 bits: 51.3 E(85289): 4.9e-07 Smith-Waterman score: 169; 45.1% identity (82.4% similar) in 51 aa overlap (51-100:45-95) 30 40 50 60 70 80 pF1KB4 TYMDNWRQNTTAEQEALQAKVDAENFYYVILYLMVMIGMFSFIIVAILVSTVKSKRREHS ::.....:.:.:. ..:..: ..::. ::: NP_001 KLWQETVQQGGNMSGLARRSPRSSDGKLEALYVLMVLGFFGFFTLGIMLSYIRSKKLEHS 20 30 40 50 60 70 90 100 110 120 pF1KB4 NDPYHQYIVED-WQEKYKSQILNLEESKATIHENIGAAGFKMSP :::.. :: : :::: :. . NP_001 NDPFNVYIESDAWQEKDKAYVQARVLESYRSCYVVENHLAIEQPNTHLPETKPSP 80 90 100 110 120 >>NP_000210 (OMIM: 176261,612347,613695) potassium volta (129 aa) initn: 167 init1: 140 opt: 169 Z-score: 247.3 bits: 51.3 E(85289): 4.9e-07 Smith-Waterman score: 169; 45.1% identity (82.4% similar) in 51 aa overlap (51-100:45-95) 30 40 50 60 70 80 pF1KB4 TYMDNWRQNTTAEQEALQAKVDAENFYYVILYLMVMIGMFSFIIVAILVSTVKSKRREHS ::.....:.:.:. ..:..: ..::. ::: NP_000 KLWQETVQQGGNMSGLARRSPRSSDGKLEALYVLMVLGFFGFFTLGIMLSYIRSKKLEHS 20 30 40 50 60 70 90 100 110 120 pF1KB4 NDPYHQYIVED-WQEKYKSQILNLEESKATIHENIGAAGFKMSP :::.. :: : :::: :. . NP_000 NDPFNVYIESDAWQEKDKAYVQARVLESYRSCYVVENHLAIEQPNTHLPETKPSP 80 90 100 110 120 >>NP_001257334 (OMIM: 176261,612347,613695) potassium vo (129 aa) initn: 167 init1: 140 opt: 169 Z-score: 247.3 bits: 51.3 E(85289): 4.9e-07 Smith-Waterman score: 169; 45.1% identity (82.4% similar) in 51 aa overlap (51-100:45-95) 30 40 50 60 70 80 pF1KB4 TYMDNWRQNTTAEQEALQAKVDAENFYYVILYLMVMIGMFSFIIVAILVSTVKSKRREHS ::.....:.:.:. ..:..: ..::. ::: NP_001 KLWQETVQQGGNMSGLARRSPRSSDGKLEALYVLMVLGFFGFFTLGIMLSYIRSKKLEHS 20 30 40 50 60 70 90 100 110 120 pF1KB4 NDPYHQYIVED-WQEKYKSQILNLEESKATIHENIGAAGFKMSP :::.. :: : :::: :. . NP_001 NDPFNVYIESDAWQEKDKAYVQARVLESYRSCYVVENHLAIEQPNTHLPETKPSP 80 90 100 110 120 >>XP_016883831 (OMIM: 176261,612347,613695) PREDICTED: p (150 aa) initn: 167 init1: 140 opt: 169 Z-score: 246.2 bits: 51.3 E(85289): 5.6e-07 Smith-Waterman score: 169; 45.1% identity (82.4% similar) in 51 aa overlap (51-100:66-116) 30 40 50 60 70 80 pF1KB4 TYMDNWRQNTTAEQEALQAKVDAENFYYVILYLMVMIGMFSFIIVAILVSTVKSKRREHS ::.....:.:.:. ..:..: ..::. ::: XP_016 KLWQETVQQGGNMSGLARRSPRSSDGKLEALYVLMVLGFFGFFTLGIMLSYIRSKKLEHS 40 50 60 70 80 90 90 100 110 120 pF1KB4 NDPYHQYIVED-WQEKYKSQILNLEESKATIHENIGAAGFKMSP :::.. :: : :::: :. . XP_016 NDPFNVYIESDAWQEKDKAYVQARVLESYRSCYVVENHLAIEQPNTHLPETKPSP 100 110 120 130 140 150 123 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 06:29:27 2016 done: Sat Nov 5 06:29:28 2016 Total Scan time: 4.300 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]