FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB4619, 384 aa 1>>>pF1KB4619 384 - 384 aa - 384 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.8536+/-0.000724; mu= 15.8060+/- 0.044 mean_var=101.5169+/-19.629, 0's: 0 Z-trim(112.8): 77 B-trim: 5 in 1/51 Lambda= 0.127293 statistics sampled from 13429 (13512) to 13429 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.756), E-opt: 0.2 (0.415), width: 16 Scan time: 2.960 The best scores are: opt bits E(32554) CCDS1480.1 CD46 gene_id:4179|Hs108|chr1 ( 384) 2725 510.4 1.1e-144 CCDS31008.1 CD46 gene_id:4179|Hs108|chr1 ( 377) 2577 483.2 1.6e-136 CCDS1485.1 CD46 gene_id:4179|Hs108|chr1 ( 392) 2140 403.0 2.4e-112 CCDS1482.1 CD46 gene_id:4179|Hs108|chr1 ( 399) 2140 403.0 2.4e-112 CCDS1479.1 CD46 gene_id:4179|Hs108|chr1 ( 349) 2103 396.1 2.4e-110 CCDS31009.1 CD46 gene_id:4179|Hs108|chr1 ( 362) 2103 396.2 2.5e-110 CCDS1481.1 CD46 gene_id:4179|Hs108|chr1 ( 369) 2103 396.2 2.6e-110 CCDS1484.1 CD46 gene_id:4179|Hs108|chr1 ( 355) 2078 391.6 6e-109 CCDS1477.1 C4BPA gene_id:722|Hs108|chr1 ( 597) 638 127.3 3.6e-29 CCDS44309.1 CR1 gene_id:1378|Hs108|chr1 (2039) 507 103.7 1.6e-21 CCDS44308.1 CR1 gene_id:1378|Hs108|chr1 (2489) 507 103.8 1.8e-21 CCDS31006.1 CD55 gene_id:1604|Hs108|chr1 ( 381) 402 83.8 2.8e-16 CCDS44307.1 CD55 gene_id:1604|Hs108|chr1 ( 440) 402 83.8 3.2e-16 CCDS73022.1 CD55 gene_id:1604|Hs108|chr1 ( 444) 402 83.9 3.2e-16 CCDS44310.1 CR1L gene_id:1379|Hs108|chr1 ( 569) 380 79.9 6.3e-15 CCDS55189.1 CSMD1 gene_id:64478|Hs108|chr8 (3564) 371 78.9 7.8e-14 CCDS1283.1 SELE gene_id:6401|Hs108|chr1 ( 610) 360 76.3 8.5e-14 CCDS60082.1 CSMD2 gene_id:114784|Hs108|chr1 (3631) 361 77.1 2.8e-13 CCDS1478.1 CR2 gene_id:1380|Hs108|chr1 (1033) 347 74.1 6.6e-13 CCDS1282.1 SELP gene_id:6403|Hs108|chr1 ( 830) 342 73.1 1.1e-12 CCDS31007.1 CR2 gene_id:1380|Hs108|chr1 (1092) 339 72.6 1.9e-12 CCDS1388.1 F13B gene_id:2165|Hs108|chr1 ( 661) 320 68.9 1.5e-11 CCDS10659.1 SEZ6L2 gene_id:26470|Hs108|chr16 ( 910) 315 68.1 3.5e-11 CCDS45458.1 SEZ6L2 gene_id:26470|Hs108|chr16 ( 809) 310 67.2 6.1e-11 CCDS10658.1 SEZ6L2 gene_id:26470|Hs108|chr16 ( 853) 310 67.2 6.3e-11 CCDS58447.1 SEZ6L2 gene_id:26470|Hs108|chr16 ( 879) 310 67.2 6.5e-11 CCDS73865.1 SEZ6L2 gene_id:26470|Hs108|chr16 ( 923) 310 67.2 6.7e-11 >>CCDS1480.1 CD46 gene_id:4179|Hs108|chr1 (384 aa) initn: 2725 init1: 2725 opt: 2725 Z-score: 2711.2 bits: 510.4 E(32554): 1.1e-144 Smith-Waterman score: 2725; 100.0% identity (100.0% similar) in 384 aa overlap (1-384:1-384) 10 20 30 40 50 60 pF1KB4 MEPPGRRECPFPSWRFPGLLLAAMVLLLYSFSDACEEPPTFEAMELIGKPKPYYEIGERV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 MEPPGRRECPFPSWRFPGLLLAAMVLLLYSFSDACEEPPTFEAMELIGKPKPYYEIGERV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 DYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGTYEFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 DYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGTYEFG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 YQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 YQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 FEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVVENGKQIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 FEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVVENGKQIS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 GFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKVSTSSTTKSPASSAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 GFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKVSTSSTTKSPASSAS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 GPRPTYKPPVSNYPGYPKPEEGILDSLDVWVIAVIVIAIVVGVAVICVVPYRYLQRRKKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 GPRPTYKPPVSNYPGYPKPEEGILDSLDVWVIAVIVIAIVVGVAVICVVPYRYLQRRKKK 310 320 330 340 350 360 370 380 pF1KB4 GKADGGAEYATYQTKSTTPAEQRG :::::::::::::::::::::::: CCDS14 GKADGGAEYATYQTKSTTPAEQRG 370 380 >>CCDS31008.1 CD46 gene_id:4179|Hs108|chr1 (377 aa) initn: 2577 init1: 2577 opt: 2577 Z-score: 2564.4 bits: 483.2 E(32554): 1.6e-136 Smith-Waterman score: 2577; 100.0% identity (100.0% similar) in 361 aa overlap (1-361:1-361) 10 20 30 40 50 60 pF1KB4 MEPPGRRECPFPSWRFPGLLLAAMVLLLYSFSDACEEPPTFEAMELIGKPKPYYEIGERV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 MEPPGRRECPFPSWRFPGLLLAAMVLLLYSFSDACEEPPTFEAMELIGKPKPYYEIGERV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 DYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGTYEFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 DYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGTYEFG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 YQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 YQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 FEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVVENGKQIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 FEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVVENGKQIS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 GFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKVSTSSTTKSPASSAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 GFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKVSTSSTTKSPASSAS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 GPRPTYKPPVSNYPGYPKPEEGILDSLDVWVIAVIVIAIVVGVAVICVVPYRYLQRRKKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 GPRPTYKPPVSNYPGYPKPEEGILDSLDVWVIAVIVIAIVVGVAVICVVPYRYLQRRKKK 310 320 330 340 350 360 370 380 pF1KB4 GKADGGAEYATYQTKSTTPAEQRG : CCDS31 GTYLTDETHREVKFTSL 370 >>CCDS1485.1 CD46 gene_id:4179|Hs108|chr1 (392 aa) initn: 2179 init1: 2115 opt: 2140 Z-score: 2130.4 bits: 403.0 E(32554): 2.4e-112 Smith-Waterman score: 2537; 96.0% identity (96.0% similar) in 376 aa overlap (1-361:1-376) 10 20 30 40 50 60 pF1KB4 MEPPGRRECPFPSWRFPGLLLAAMVLLLYSFSDACEEPPTFEAMELIGKPKPYYEIGERV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 MEPPGRRECPFPSWRFPGLLLAAMVLLLYSFSDACEEPPTFEAMELIGKPKPYYEIGERV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 DYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGTYEFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 DYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGTYEFG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 YQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 YQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 FEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVVENGKQIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 FEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVVENGKQIS 190 200 210 220 230 240 250 260 270 280 pF1KB4 GFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKV-------------- :::::::::::::::::::::::::::::::::::::::::::::: CCDS14 GFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKVLPPSSTKPPALSHS 250 260 270 280 290 300 290 300 310 320 330 340 pF1KB4 -STSSTTKSPASSASGPRPTYKPPVSNYPGYPKPEEGILDSLDVWVIAVIVIAIVVGVAV ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 VSTSSTTKSPASSASGPRPTYKPPVSNYPGYPKPEEGILDSLDVWVIAVIVIAIVVGVAV 310 320 330 340 350 360 350 360 370 380 pF1KB4 ICVVPYRYLQRRKKKGKADGGAEYATYQTKSTTPAEQRG :::::::::::::::: CCDS14 ICVVPYRYLQRRKKKGTYLTDETHREVKFTSL 370 380 390 >>CCDS1482.1 CD46 gene_id:4179|Hs108|chr1 (399 aa) initn: 2179 init1: 2115 opt: 2140 Z-score: 2130.3 bits: 403.0 E(32554): 2.4e-112 Smith-Waterman score: 2685; 96.2% identity (96.2% similar) in 399 aa overlap (1-384:1-399) 10 20 30 40 50 60 pF1KB4 MEPPGRRECPFPSWRFPGLLLAAMVLLLYSFSDACEEPPTFEAMELIGKPKPYYEIGERV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 MEPPGRRECPFPSWRFPGLLLAAMVLLLYSFSDACEEPPTFEAMELIGKPKPYYEIGERV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 DYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGTYEFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 DYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGTYEFG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 YQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 YQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 FEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVVENGKQIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 FEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVVENGKQIS 190 200 210 220 230 240 250 260 270 280 pF1KB4 GFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKV-------------- :::::::::::::::::::::::::::::::::::::::::::::: CCDS14 GFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKVLPPSSTKPPALSHS 250 260 270 280 290 300 290 300 310 320 330 340 pF1KB4 -STSSTTKSPASSASGPRPTYKPPVSNYPGYPKPEEGILDSLDVWVIAVIVIAIVVGVAV ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 VSTSSTTKSPASSASGPRPTYKPPVSNYPGYPKPEEGILDSLDVWVIAVIVIAIVVGVAV 310 320 330 340 350 360 350 360 370 380 pF1KB4 ICVVPYRYLQRRKKKGKADGGAEYATYQTKSTTPAEQRG ::::::::::::::::::::::::::::::::::::::: CCDS14 ICVVPYRYLQRRKKKGKADGGAEYATYQTKSTTPAEQRG 370 380 390 >>CCDS1479.1 CD46 gene_id:4179|Hs108|chr1 (349 aa) initn: 2336 init1: 2078 opt: 2103 Z-score: 2094.4 bits: 396.1 E(32554): 2.4e-110 Smith-Waterman score: 2310; 95.6% identity (95.6% similar) in 339 aa overlap (1-339:1-324) 10 20 30 40 50 60 pF1KB4 MEPPGRRECPFPSWRFPGLLLAAMVLLLYSFSDACEEPPTFEAMELIGKPKPYYEIGERV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 MEPPGRRECPFPSWRFPGLLLAAMVLLLYSFSDACEEPPTFEAMELIGKPKPYYEIGERV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 DYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGTYEFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 DYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGTYEFG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 YQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 YQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 FEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVVENGKQIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 FEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVVENGKQIS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 GFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKVSTSSTTKSPASSAS ::::::::::::::::::::::::::::::::::::::::::::: CCDS14 GFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLK--------------- 250 260 270 280 310 320 330 340 350 360 pF1KB4 GPRPTYKPPVSNYPGYPKPEEGILDSLDVWVIAVIVIAIVVGVAVICVVPYRYLQRRKKK ::::::::::::::::::::::::::::::::::::::: CCDS14 GPRPTYKPPVSNYPGYPKPEEGILDSLDVWVIAVIVIAIGKQMVELNMPLTRLNQPLQQS 290 300 310 320 330 340 370 380 pF1KB4 GKADGGAEYATYQTKSTTPAEQRG CCDS14 REAE >>CCDS31009.1 CD46 gene_id:4179|Hs108|chr1 (362 aa) initn: 2482 init1: 2078 opt: 2103 Z-score: 2094.2 bits: 396.2 E(32554): 2.5e-110 Smith-Waterman score: 2456; 95.8% identity (95.8% similar) in 361 aa overlap (1-361:1-346) 10 20 30 40 50 60 pF1KB4 MEPPGRRECPFPSWRFPGLLLAAMVLLLYSFSDACEEPPTFEAMELIGKPKPYYEIGERV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 MEPPGRRECPFPSWRFPGLLLAAMVLLLYSFSDACEEPPTFEAMELIGKPKPYYEIGERV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 DYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGTYEFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 DYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGTYEFG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 YQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 YQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 FEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVVENGKQIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 FEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVVENGKQIS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 GFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKVSTSSTTKSPASSAS ::::::::::::::::::::::::::::::::::::::::::::: CCDS31 GFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLK--------------- 250 260 270 280 310 320 330 340 350 360 pF1KB4 GPRPTYKPPVSNYPGYPKPEEGILDSLDVWVIAVIVIAIVVGVAVICVVPYRYLQRRKKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 GPRPTYKPPVSNYPGYPKPEEGILDSLDVWVIAVIVIAIVVGVAVICVVPYRYLQRRKKK 290 300 310 320 330 340 370 380 pF1KB4 GKADGGAEYATYQTKSTTPAEQRG : CCDS31 GTYLTDETHREVKFTSL 350 360 >>CCDS1481.1 CD46 gene_id:4179|Hs108|chr1 (369 aa) initn: 2630 init1: 2078 opt: 2103 Z-score: 2094.1 bits: 396.2 E(32554): 2.6e-110 Smith-Waterman score: 2604; 96.1% identity (96.1% similar) in 384 aa overlap (1-384:1-369) 10 20 30 40 50 60 pF1KB4 MEPPGRRECPFPSWRFPGLLLAAMVLLLYSFSDACEEPPTFEAMELIGKPKPYYEIGERV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 MEPPGRRECPFPSWRFPGLLLAAMVLLLYSFSDACEEPPTFEAMELIGKPKPYYEIGERV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 DYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGTYEFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 DYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGTYEFG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 YQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 YQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 FEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVVENGKQIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 FEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVVENGKQIS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 GFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKVSTSSTTKSPASSAS ::::::::::::::::::::::::::::::::::::::::::::: CCDS14 GFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLK--------------- 250 260 270 280 310 320 330 340 350 360 pF1KB4 GPRPTYKPPVSNYPGYPKPEEGILDSLDVWVIAVIVIAIVVGVAVICVVPYRYLQRRKKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 GPRPTYKPPVSNYPGYPKPEEGILDSLDVWVIAVIVIAIVVGVAVICVVPYRYLQRRKKK 290 300 310 320 330 340 370 380 pF1KB4 GKADGGAEYATYQTKSTTPAEQRG :::::::::::::::::::::::: CCDS14 GKADGGAEYATYQTKSTTPAEQRG 350 360 >>CCDS1484.1 CD46 gene_id:4179|Hs108|chr1 (355 aa) initn: 2521 init1: 2078 opt: 2078 Z-score: 2069.5 bits: 391.6 E(32554): 6e-109 Smith-Waterman score: 2467; 92.4% identity (92.4% similar) in 384 aa overlap (1-384:1-355) 10 20 30 40 50 60 pF1KB4 MEPPGRRECPFPSWRFPGLLLAAMVLLLYSFSDACEEPPTFEAMELIGKPKPYYEIGERV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 MEPPGRRECPFPSWRFPGLLLAAMVLLLYSFSDACEEPPTFEAMELIGKPKPYYEIGERV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 DYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGTYEFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 DYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGTYEFG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 YQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 YQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 FEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVVENGKQIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 FEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVVENGKQIS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 GFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKVSTSSTTKSPASSAS ::::::::::::::::::::::::::::::::::::::::::::: CCDS14 GFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLK--------------- 250 260 270 280 310 320 330 340 350 360 pF1KB4 GPRPTYKPPVSNYPGYPKPEEGILDSLDVWVIAVIVIAIVVGVAVICVVPYRYLQRRKKK :::::::::::::::::::::::::::::::::::::::::::::: CCDS14 --------------GYPKPEEGILDSLDVWVIAVIVIAIVVGVAVICVVPYRYLQRRKKK 290 300 310 320 330 370 380 pF1KB4 GKADGGAEYATYQTKSTTPAEQRG :::::::::::::::::::::::: CCDS14 GKADGGAEYATYQTKSTTPAEQRG 340 350 >>CCDS1477.1 C4BPA gene_id:722|Hs108|chr1 (597 aa) initn: 452 init1: 261 opt: 638 Z-score: 637.2 bits: 127.3 E(32554): 3.6e-29 Smith-Waterman score: 638; 36.7% identity (55.8% similar) in 308 aa overlap (10-305:21-317) 10 20 30 40 pF1KB4 MEPPGRRECPFPS-WRFPGLLLAAMVL---LLYSFSDACEEPPT--FEA :: :. .: :.: :: . : ::: : : CCDS14 MHPPKTPSGALHRKRKMAAWPFSRLWKVSDPILFQMTLIAALLPAVLGNCGPPPTLSFAA 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB4 MELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTI-CDRNHTWLPVSDDACYRETCPYI : . .. : . : : :: . .:.:. :. . : : . : . : . CCDS14 PMDITLTETRFKTGTTLKYTCLPGY--VRSHSTQTLTCNSDGEW--VYNTFCIYKRCRHP 70 80 90 100 110 110 120 130 140 150 160 pF1KB4 RDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLC . ::: : . :: :..: :.::..::: ::.. . :: : :: : : CCDS14 GELRNGQ-VEIKTDLSFGSQIEFSCSEGFFLIGSTTSRCEVQDRGVGWSHPLPQCEIVKC 120 130 140 150 160 170 170 180 190 200 210 pF1KB4 TPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCG-DN---SVWSR ::: :.::.:. .: . . : .::::::: :::.:...: : .: .:: CCDS14 KPPPDIRNGRHS-GEENFYAYGFSVTYSCDPR-----FSLLGHASISCTVENETIGVWRP 180 190 200 210 220 220 230 240 250 260 270 pF1KB4 AAPECKVVKCRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDP . : :. . :: : : .:...:::: . :: :..:.:.::: : ::..: ::..: :.: CCDS14 SPPTCEKITCRKPDVSHGEMVSGFGPIYNYKDTIVFKCQKGFVLRGSSVIHCDADSKWNP 230 240 250 260 270 280 280 290 300 310 320 330 pF1KB4 PVPKCLKVSTSSTTKSP-ASSASGPRPTYKPPVSNYPGYPKPEEGILDSLDVWVIAVIVI : : : . : :: . :::: CCDS14 SPPACEPNSCINLPDIPHASWETYPRPTKEDVYVVGTVLRYRCHPGYKPTTDEPTTVICQ 290 300 310 320 330 340 >-- initn: 283 init1: 126 opt: 376 Z-score: 377.2 bits: 79.2 E(32554): 1.1e-14 Smith-Waterman score: 393; 30.8% identity (54.4% similar) in 237 aa overlap (54-283:322-538) 30 40 50 60 70 80 pF1KB4 MVLLLYSFSDACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRN : .: . :.:. :: : .::..: CCDS14 PACEPNSCINLPDIPHASWETYPRPTKEDVYVVGTVLRYRCHPGYKPTTDEPTTVICQKN 300 310 320 330 340 350 90 100 110 120 130 pF1KB4 HTWLPVSDDACYRETCPYIRDPLNGQAV------PANG-TYEFGYQMHFICNEGYYLIGE : : ..: :: . ::. . ::: .: .: .. : :.: . . CCDS14 LRWTPY--QGCEALCCPEPKLN-NGEITQHRKSRPANHCVYFYGDEISFSCHETSRFSA- 360 370 380 390 400 140 150 160 170 180 190 pF1KB4 EILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPG :. :. :: . : : . :. :::: .:.. : : . . . : :: . CCDS14 ---ICQGDGT---WSPRTPSCGDI-CNFPPKIAHGHYKQSSSYSF-FKEEIIYECDKG-- 410 420 430 440 450 200 210 220 230 240 250 pF1KB4 PDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVVENGKQISGFGKKFYYKATVMFEC . :.:.. . :. : :: ::.::.. :: : . ::. .: .. .: ..: CCDS14 ---YILVGQAKLSCS-YSHWSAPAPQCKAL-CRKPELVNGR-LSVDKDQYVEPENVTIQC 460 470 480 490 500 510 260 270 280 290 300 310 pF1KB4 DKGFYLDGSDTIVCDSNSTWDPPVPKCLKVSTSSTTKSPASSASGPRPTYKPPVSNYPGY :.:. . : ..:.:..: :: : :::: CCDS14 DSGYGVVGPQSITCSGNRTWYPEVPKCEWETPEGCEQVLTGKRLMQCLPNPEDVKMALEV 520 530 540 550 560 570 >>CCDS44309.1 CR1 gene_id:1378|Hs108|chr1 (2039 aa) initn: 389 init1: 277 opt: 507 Z-score: 500.1 bits: 103.7 E(32554): 1.6e-21 Smith-Waterman score: 558; 34.3% identity (57.4% similar) in 289 aa overlap (2-278:10-288) 10 20 30 40 pF1KB4 MEPPGRRECPFPSWRF--PGLLLAAMVLLLYSFS-DACEEP---PTFEAMEL :: : : :. : : :::..::: . :. : : . .: CCDS44 MGASSPRSPEPVGP---PAPGLPFCCGGSLLAVVVLLALPVAWGQCNAPEWLPFARPTNL 10 20 30 40 50 50 60 70 80 90 100 pF1KB4 IGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPL . . . :: ..:.:. :: : :: .: .: ..: : :..: ::. CCDS44 TDEFE--FPIGTYLNYECRPGYSGRP---FSIICLKNSVWTGAKDR-CRRKSCRNPPDPV 60 70 80 90 100 110 110 120 130 140 150 160 pF1KB4 NGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPP ::.. .: .:: :... :..:: ::: : ..:...::... :::... : :: CCDS44 NGMVHVIKGI-QFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDRIPCGLPP 120 130 140 150 160 170 170 180 190 200 210 220 pF1KB4 KIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDP-FSLIGESTIYCGDNS----VWSRAAP : :: .. : :.: ..::: :.:. : : :.:: .::: .:. .:: :: CCDS44 TITNGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAP 180 190 200 210 220 230 230 240 250 260 270 280 pF1KB4 ECKVV-KCRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPV .: . :: : :::: .: . : . .: :.:. :: . : . :.. . :.: CCDS44 QCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPEL 240 250 260 270 280 290 290 300 310 320 330 340 pF1KB4 PKCLKVSTSSTTKSPASSASGPRPTYKPPVSNYPGYPKPEEGILDSLDVWVIAVIVIAIV CCDS44 PSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAA 300 310 320 330 340 350 >-- initn: 896 init1: 220 opt: 558 Z-score: 550.7 bits: 113.1 E(32554): 2.4e-24 Smith-Waterman score: 558; 34.7% identity (56.4% similar) in 259 aa overlap (35-286:1396-1649) 10 20 30 40 50 60 pF1KB4 GRRECPFPSWRFPGLLLAAMVLLLYSFSDACEEPPTFE-AMELIGKPKPYYEIGERVDYK :. : : : : . .: ..:. CCDS44 STIRCTSDPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFASPTIPINDFEFPVGTSLNYE 1370 1380 1390 1400 1410 1420 70 80 90 100 110 120 pF1KB4 CKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGTYEFGYQM :. ::: : .: .: : .: : :..: .:.::. : : .:: . CCDS44 CRPGYF---GKMFSISCLENLVWSSV-EDNCRRKSCGPPPEPFNGM-VHINTDTQFGSTV 1430 1440 1450 1460 1470 1480 130 140 150 160 170 180 pF1KB4 HFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEY .. ::::. ::: : ..:. . :. : :::: . : ::: :.:: .. :. CCDS44 NYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISCEPPPTISNGDFYSNNRTSFHN 1490 1500 1510 1520 1530 1540 190 200 210 220 230 pF1KB4 LDAVTYSCDPAP-GPDPFSLIGESTIYCG--DNSV--WSRAAPEC-KVVKCRFPVVENGK .:::.: .: : . : :.:: .::: :..: :: :.: .. :: : :::. CCDS44 GTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSSPPPRCISTNKCTAPEVENAI 1550 1560 1570 1580 1590 1600 240 250 260 270 280 290 pF1KB4 QISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKVSTSSTTKSPAS .. : . : . :.:. :: . :: :. :..:. : : .:.: .: CCDS44 RVPGNRSFFTLTEIIRFRCQPGFVMVGSHTVQCQTNGRWGPKLPHCSRVCQPPPEILHGE 1610 1620 1630 1640 1650 1660 300 310 320 330 340 350 pF1KB4 SASGPRPTYKPPVSNYPGYPKPEEGILDSLDVWVIAVIVIAIVVGVAVICVVPYRYLQRR CCDS44 HTLSHQDNFSPGQEVFYSCEPSYDLRGAASLHCTPQGDWSPEAPRCTVKSCDDFLGQLPH 1670 1680 1690 1700 1710 1720 >-- initn: 389 init1: 277 opt: 507 Z-score: 500.1 bits: 103.7 E(32554): 1.6e-21 Smith-Waterman score: 507; 31.9% identity (57.5% similar) in 285 aa overlap (28-301:740-1013) 10 20 30 40 50 pF1KB4 MEPPGRRECPFPSWRFPGLLLAAMVLLLYSFSDACEEPPTFEAMELIGKPKPYYEIG : : : .:. :: : . : . : CCDS44 EVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPG 710 720 730 740 750 760 60 70 80 90 100 110 pF1KB4 ERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCP-YIRDPLNGQAV-PANG ..: :.:. :: . :. : . : :.. .: ..: .. . :::... :.: CCDS44 QEVFYSCEPGY-DLRGAASMR-CTPQGDWSPAAP-TCEVKSCDDFMGQLLNGRVLFPVN- 770 780 790 800 810 820 120 130 140 150 160 170 pF1KB4 TYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTF ..: .. :.:.::. : : :: : : ..:... :.::...: :: : ::.:: CCDS44 -LQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTG 830 840 850 860 870 880 180 190 200 210 220 pF1KB4 SEVEVFEYLDAVTYSCDPAPG-PDPFSLIGESTIYCGD----NSVWSRAAPECKVV-KCR . .::: . ::.:.::: : :.::::::: : . :.::: ::.: .. .:. CCDS44 KPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQ 890 900 910 920 930 940 230 240 250 260 270 280 pF1KB4 FP--VVENGKQISGFGKKFYYKATVMFECDKGFYLDGSD-TIVCDSNSTWDPPVPKCLKV : . . . .. : ... .:: .: : .:.: .: .:. : : . CCDS44 APDHFLFAKLKTQTNASDFPIGTSLKYECRPEYY--GRPFSITCLDNLVWSSPKDVCKRK 950 960 970 980 990 1000 290 300 310 320 330 340 pF1KB4 STSSTTKSPASSASGPRPTYKPPVSNYPGYPKPEEGILDSLDVWVIAVIVIAIVVGVAVI : :.: . ..: CCDS44 SC----KTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKP 1010 1020 1030 1040 1050 >-- initn: 582 init1: 272 opt: 502 Z-score: 495.1 bits: 102.8 E(32554): 2.9e-21 Smith-Waterman score: 502; 31.6% identity (57.5% similar) in 285 aa overlap (28-301:290-563) 10 20 30 40 50 pF1KB4 MEPPGRRECPFPSWRFPGLLLAAMVLLLYSFSDACEEPPTFEAMELIGKPKPYYEIG : : : .:. :: : . : . : CCDS44 EVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPG 260 270 280 290 300 310 60 70 80 90 100 110 pF1KB4 ERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCP-YIRDPLNGQAV-PANG ..: :.:. :: . :. : . : :.. .: ..: .. . :::... :.: CCDS44 QEVFYSCEPGY-DLRGAASMR-CTPQGDWSPAAP-TCEVKSCDDFMGQLLNGRVLFPVN- 320 330 340 350 360 370 120 130 140 150 160 170 pF1KB4 TYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTF ..: .. :.:.::. : : :: : : ..:... :.::...: :: : ::.:: CCDS44 -LQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTG 380 390 400 410 420 430 180 190 200 210 220 pF1KB4 SEVEVFEYLDAVTYSCDPAPG-PDPFSLIGESTIYCGD----NSVWSRAAPECKVV-KCR . .::: . .:.:.::: : :.::::::: : . :.::: ::.: .. .:. CCDS44 KPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQ 440 450 460 470 480 490 230 240 250 260 270 280 pF1KB4 FP--VVENGKQISGFGKKFYYKATVMFECDKGFYLDGSD-TIVCDSNSTWDPPVPKCLKV : . . . .. : ... .:: .: : .:.: .: .:. : : . CCDS44 APDHFLFAKLKTQTNASDFPIGTSLKYECRPEYY--GRPFSITCLDNLVWSSPKDVCKRK 500 510 520 530 540 550 290 300 310 320 330 340 pF1KB4 STSSTTKSPASSASGPRPTYKPPVSNYPGYPKPEEGILDSLDVWVIAVIVIAIVVGVAVI : :.: . ..: CCDS44 SC----KTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKP 560 570 580 590 600 >-- initn: 512 init1: 198 opt: 464 Z-score: 457.4 bits: 95.8 E(32554): 3.7e-19 Smith-Waterman score: 464; 30.1% identity (55.3% similar) in 266 aa overlap (35-289:1650-1910) 10 20 30 40 50 60 pF1KB4 GRRECPFPSWRFPGLLLAAMVLLLYSFSDACEEPPTFEAMELIGKPKPYYEIGERVDYKC :. :: . : . . . :..: :.: CCDS44 QPGFVMVGSHTVQCQTNGRWGPKLPHCSRVCQPPPEILHGEHTLSHQDNFSPGQEVFYSC 1620 1630 1640 1650 1660 1670 70 80 90 100 110 120 pF1KB4 KKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPL-NGQAV-PANGTYEFGYQ . .: . : : . : : . : ..: . : .:... : : ..: . CCDS44 EPSYDLRGAASLH--CTPQGDWSPEAPR-CTVKSCDDFLGQLPHGRVLLPLN--LQLGAK 1680 1690 1700 1710 1720 1730 130 140 150 160 170 180 pF1KB4 MHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFE . :.:.::. : :. .: : : :.:... :.::...: :: : ::.:: . . CCDS44 VSFVCDEGFRLKGRSASHCVLAGMKALWNSSVPVCEQIFCPNPPAILNGRHTGTPFGDIP 1740 1750 1760 1770 1780 1790 190 200 210 220 230 pF1KB4 YLDAVTYSCDPAPGPD-PFSLIGESTIYCGD----NSVWSRAAPECKV---VKCRFPV-V : ..:.:: : :.:::::.: : . :.::: ::.:.. . : : . CCDS44 YGKEISYACDTHPDRGMTFNLIGESSIRCTSDPQGNGVWSSPAPRCELSVPAACPHPPKI 1800 1810 1820 1830 1840 1850 240 250 260 270 280 290 pF1KB4 ENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKVSTSSTTK .::. :.: . . :. . :: :. : :. : : ... :. : .:. : CCDS44 QNGHYIGGHVSLYLPGMTISYICDPGYLLVGKGFIFCTDQGIWSQLDHYCKEVNCSFPLF 1860 1870 1880 1890 1900 1910 300 310 320 330 340 350 pF1KB4 SPASSASGPRPTYKPPVSNYPGYPKPEEGILDSLDVWVIAVIVIAIVVGVAVICVVPYRY CCDS44 MNGISKELEMKKVYHYGDYVTLKCEDGYTLEGSPWSQCQADDRWDPPLAKCTSRTHDALI 1920 1930 1940 1950 1960 1970 >-- initn: 495 init1: 219 opt: 439 Z-score: 432.6 bits: 91.2 E(32554): 8.9e-18 Smith-Waterman score: 439; 33.5% identity (57.4% similar) in 209 aa overlap (118-316:1022-1230) 90 100 110 120 130 140 pF1KB4 PVSDDACYRETCPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSV . : .... :. :. :::. : :.:.. CCDS44 WSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNT 1000 1010 1020 1030 1040 1050 150 160 170 180 190 200 pF1KB4 AIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCD-PAPGPDPFSLIGES : :: :::::... : :: : :: .. : :.: ..::: :. . : : :.:: CCDS44 AHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEP 1060 1070 1080 1090 1100 1110 210 220 230 240 250 260 pF1KB4 TIYCGDNS----VWSRAAPECKVV-KCRFPVVENGKQISGFGKKFYYKATVMFECDKGFY .::: .:. .:: ::.: . :: : :::: .: . : . .: :.:. :: CCDS44 SIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFV 1120 1130 1140 1150 1160 1170 270 280 290 300 310 pF1KB4 LDGSDTIVCDSNSTWDPPVPKCLKVSTSSTTKSPASSASGPRPTYKPP----VSNYPGYP . : . :.. . :.: .:.: .: . . . . ...: : ::: CCDS44 MKGPRRVKCQALNKWEPELPSCSRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYD 1180 1190 1200 1210 1220 1230 320 330 340 350 360 370 pF1KB4 KPEEGILDSLDVWVIAVIVIAIVVGVAVICVVPYRYLQRRKKKGKADGGAEYATYQTKST CCDS44 LRGAASLHCTPQGDWSPEAPRCAVKSCDDFLGQLPHGRVLFPLNLQLGAKVSFVCDEGFR 1240 1250 1260 1270 1280 1290 >-- initn: 414 init1: 203 opt: 425 Z-score: 418.7 bits: 88.6 E(32554): 5.3e-17 Smith-Waterman score: 425; 37.7% identity (61.7% similar) in 167 aa overlap (118-278:572-738) 90 100 110 120 130 140 pF1KB4 PVSDDACYRETCPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSV . : .... :. :. :::. : :.:.. CCDS44 WSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNA 550 560 570 580 590 600 150 160 170 180 190 200 pF1KB4 AIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDP-FSLIGES : :: :::::... : :: : :: .. : :.: ..::: :.:. : : :.:: CCDS44 AHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEP 610 620 630 640 650 660 210 220 230 240 250 260 pF1KB4 TIYCGDNS----VWSRAAPECKVV-KCRFPVVENGKQISGFGKKFYYKATVMFECDKGFY .::: .:. .:: ::.: . :: : :::: .: . : . .: :.:. :: CCDS44 SIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFV 670 680 690 700 710 720 270 280 290 300 310 320 pF1KB4 LDGSDTIVCDSNSTWDPPVPKCLKVSTSSTTKSPASSASGPRPTYKPPVSNYPGYPKPEE . : . :.. . :.: CCDS44 MKGPRRVKCQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYD 730 740 750 760 770 780 >-- initn: 307 init1: 205 opt: 343 Z-score: 337.3 bits: 73.6 E(32554): 1.8e-12 Smith-Waterman score: 343; 34.6% identity (60.1% similar) in 153 aa overlap (80-225:1240-1389) 50 60 70 80 90 100 pF1KB4 PKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPL-NG : . : : . : ..: . : .: CCDS44 PSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTPQGDWSPEAPR-CAVKSCDDFLGQLPHG 1210 1220 1230 1240 1250 1260 110 120 130 140 150 160 pF1KB4 QAV-PANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPK ... : : ..: .. :.:.::. : : . .: : : ..:... :.::...: :: CCDS44 RVLFPLN--LQLGAKVSFVCDEGFRLKGSSVSHCVLVGMRSLWNNSVPVCEHIFCPNPPA 1270 1280 1290 1300 1310 1320 170 180 190 200 210 220 pF1KB4 IKNGKHTFSEVEVFEYLDAVTYSCDPAPGPD-PFSLIGESTIYCGD----NSVWSRAAPE : ::.:: . . : ..:.::: : :.::::::: : . :.::: ::. CCDS44 ILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIGESTIRCTSDPHGNGVWSSPAPR 1330 1340 1350 1360 1370 1380 230 240 250 260 270 280 pF1KB4 CKVVKCRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPK :.. CCDS44 CELSVRAGHCKTPEQFPFASPTIPINDFEFPVGTSLNYECRPGYFGKMFSISCLENLVWS 1390 1400 1410 1420 1430 1440 384 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 03:05:58 2016 done: Fri Nov 4 03:05:59 2016 Total Scan time: 2.960 Total Display time: 0.090 Function used was FASTA [36.3.4 Apr, 2011]