FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB4619, 384 aa 1>>>pF1KB4619 384 - 384 aa - 384 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.3438+/-0.000302; mu= 13.1655+/- 0.019 mean_var=106.8231+/-20.985, 0's: 0 Z-trim(120.1): 176 B-trim: 19 in 1/53 Lambda= 0.124091 statistics sampled from 34647 (34839) to 34647 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.753), E-opt: 0.2 (0.408), width: 16 Scan time: 8.650 The best scores are: opt bits E(85289) NP_722548 (OMIM: 120920,612922) membrane cofactor ( 384) 2725 498.0 1.5e-140 XP_011507865 (OMIM: 120920,612922) PREDICTED: memb ( 385) 2578 471.7 1.3e-132 NP_758861 (OMIM: 120920,612922) membrane cofactor ( 377) 2577 471.5 1.4e-132 XP_016856797 (OMIM: 120920,612922) PREDICTED: memb ( 378) 2430 445.2 1.2e-124 XP_016856798 (OMIM: 120920,612922) PREDICTED: memb ( 363) 2178 400.1 4.4e-111 XP_011507866 (OMIM: 120920,612922) PREDICTED: memb ( 370) 2178 400.1 4.4e-111 NP_002380 (OMIM: 120920,612922) membrane cofactor ( 392) 2140 393.3 5.2e-109 NP_758869 (OMIM: 120920,612922) membrane cofactor ( 399) 2140 393.3 5.2e-109 NP_758860 (OMIM: 120920,612922) membrane cofactor ( 349) 2103 386.6 4.6e-107 NP_758862 (OMIM: 120920,612922) membrane cofactor ( 362) 2103 386.7 4.8e-107 NP_758863 (OMIM: 120920,612922) membrane cofactor ( 369) 2103 386.7 4.9e-107 XP_016856799 (OMIM: 120920,612922) PREDICTED: memb ( 348) 2078 382.2 1e-105 NP_758871 (OMIM: 120920,612922) membrane cofactor ( 355) 2078 382.2 1e-105 XP_005273309 (OMIM: 120830) PREDICTED: C4b-binding ( 597) 638 124.5 6.4e-28 NP_000706 (OMIM: 120830) C4b-binding protein alpha ( 597) 638 124.5 6.4e-28 XP_005273308 (OMIM: 120830) PREDICTED: C4b-binding ( 597) 638 124.5 6.4e-28 NP_000564 (OMIM: 120620,607486,611162) complement (2039) 507 101.5 1.9e-20 XP_006711229 (OMIM: 120620,607486,611162) PREDICTE (2459) 507 101.5 2.2e-20 NP_000642 (OMIM: 120620,607486,611162) complement (2489) 507 101.5 2.2e-20 XP_011507507 (OMIM: 120620,607486,611162) PREDICTE (2554) 507 101.5 2.3e-20 NP_000565 (OMIM: 125240,613793) complement decay-a ( 381) 402 82.1 2.3e-15 NP_001287833 (OMIM: 125240,613793) complement deca ( 384) 402 82.1 2.3e-15 XP_016855956 (OMIM: 125240,613793) PREDICTED: comp ( 412) 402 82.2 2.5e-15 NP_001287832 (OMIM: 125240,613793) complement deca ( 439) 402 82.2 2.6e-15 NP_001108224 (OMIM: 125240,613793) complement deca ( 440) 402 82.2 2.6e-15 NP_001287831 (OMIM: 125240,613793) complement deca ( 444) 402 82.2 2.6e-15 NP_783641 (OMIM: 605886) complement component rece ( 569) 380 78.3 4.9e-14 XP_011533056 (OMIM: 608397) PREDICTED: CUB and sus (2238) 371 77.1 4.4e-13 XP_011533055 (OMIM: 608397) PREDICTED: CUB and sus (2595) 371 77.2 4.9e-13 XP_016869220 (OMIM: 608397) PREDICTED: CUB and sus (3327) 371 77.3 6e-13 NP_000441 (OMIM: 131210,145500) E-selectin precurs ( 610) 360 74.8 6.2e-13 XP_011533054 (OMIM: 608397) PREDICTED: CUB and sus (3549) 371 77.3 6.3e-13 NP_150094 (OMIM: 608397) CUB and sushi domain-cont (3564) 371 77.3 6.4e-13 XP_016855679 (OMIM: 608398) PREDICTED: CUB and sus (3362) 361 75.5 2.1e-12 XP_016855678 (OMIM: 608398) PREDICTED: CUB and sus (3506) 361 75.5 2.2e-12 XP_016855683 (OMIM: 608398) PREDICTED: CUB and sus (3566) 361 75.5 2.2e-12 XP_016855677 (OMIM: 608398) PREDICTED: CUB and sus (3567) 361 75.5 2.2e-12 XP_016855676 (OMIM: 608398) PREDICTED: CUB and sus (3606) 361 75.5 2.2e-12 XP_016855674 (OMIM: 608398) PREDICTED: CUB and sus (3607) 361 75.5 2.2e-12 XP_016855675 (OMIM: 608398) PREDICTED: CUB and sus (3607) 361 75.5 2.2e-12 NP_001268885 (OMIM: 608398) CUB and sushi domain-c (3631) 361 75.5 2.2e-12 NP_001868 (OMIM: 120650,240500,610927,614699) comp (1033) 347 72.6 4.7e-12 XP_005245497 (OMIM: 147050,173610) PREDICTED: P-se ( 768) 342 71.6 6.9e-12 XP_005245496 (OMIM: 147050,173610) PREDICTED: P-se ( 790) 342 71.6 7.1e-12 XP_005245495 (OMIM: 147050,173610) PREDICTED: P-se ( 790) 342 71.6 7.1e-12 XP_005245493 (OMIM: 147050,173610) PREDICTED: P-se ( 830) 342 71.6 7.4e-12 NP_002996 (OMIM: 147050,173610) P-selectin precurs ( 830) 342 71.6 7.4e-12 XP_005245492 (OMIM: 147050,173610) PREDICTED: P-se ( 830) 342 71.6 7.4e-12 XP_011507508 (OMIM: 120650,240500,610927,614699) P ( 969) 339 71.2 1.2e-11 NP_001006659 (OMIM: 120650,240500,610927,614699) c (1092) 339 71.2 1.3e-11 >>NP_722548 (OMIM: 120920,612922) membrane cofactor prot (384 aa) initn: 2725 init1: 2725 opt: 2725 Z-score: 2644.3 bits: 498.0 E(85289): 1.5e-140 Smith-Waterman score: 2725; 100.0% identity (100.0% similar) in 384 aa overlap (1-384:1-384) 10 20 30 40 50 60 pF1KB4 MEPPGRRECPFPSWRFPGLLLAAMVLLLYSFSDACEEPPTFEAMELIGKPKPYYEIGERV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_722 MEPPGRRECPFPSWRFPGLLLAAMVLLLYSFSDACEEPPTFEAMELIGKPKPYYEIGERV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 DYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGTYEFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_722 DYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGTYEFG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 YQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_722 YQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 FEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVVENGKQIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_722 FEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVVENGKQIS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 GFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKVSTSSTTKSPASSAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_722 GFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKVSTSSTTKSPASSAS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 GPRPTYKPPVSNYPGYPKPEEGILDSLDVWVIAVIVIAIVVGVAVICVVPYRYLQRRKKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_722 GPRPTYKPPVSNYPGYPKPEEGILDSLDVWVIAVIVIAIVVGVAVICVVPYRYLQRRKKK 310 320 330 340 350 360 370 380 pF1KB4 GKADGGAEYATYQTKSTTPAEQRG :::::::::::::::::::::::: NP_722 GKADGGAEYATYQTKSTTPAEQRG 370 380 >>XP_011507865 (OMIM: 120920,612922) PREDICTED: membrane (385 aa) initn: 2115 init1: 2115 opt: 2578 Z-score: 2502.0 bits: 471.7 E(85289): 1.3e-132 Smith-Waterman score: 2578; 95.3% identity (96.4% similar) in 385 aa overlap (1-384:1-385) 10 20 30 40 50 60 pF1KB4 MEPPGRRECPFPSWRFPGLLLAAMVLLLYSFSDACEEPPTFEAMELIGKPKPYYEIGERV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MEPPGRRECPFPSWRFPGLLLAAMVLLLYSFSDACEEPPTFEAMELIGKPKPYYEIGERV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 DYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGTYEFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGTYEFG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 YQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 FEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVVENGKQIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVVENGKQIS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 GFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKVSTSSTTKSPASSAS :::::::::::::::::::::::::::::::::::::::::::::: :.:: :: : : XP_011 GFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKVLPPSSTKPPALSHS 250 260 270 280 290 300 310 320 330 340 350 pF1KB4 -GPRPTYKPPVSNYPGYPKPEEGILDSLDVWVIAVIVIAIVVGVAVICVVPYRYLQRRKK . : : :.:. ::::::::::::::::::::::::::::::::::::::::::::: XP_011 VSTSSTTKSPASSASGYPKPEEGILDSLDVWVIAVIVIAIVVGVAVICVVPYRYLQRRKK 310 320 330 340 350 360 360 370 380 pF1KB4 KGKADGGAEYATYQTKSTTPAEQRG ::::::::::::::::::::::::: XP_011 KGKADGGAEYATYQTKSTTPAEQRG 370 380 >>NP_758861 (OMIM: 120920,612922) membrane cofactor prot (377 aa) initn: 2577 init1: 2577 opt: 2577 Z-score: 2501.2 bits: 471.5 E(85289): 1.4e-132 Smith-Waterman score: 2577; 100.0% identity (100.0% similar) in 361 aa overlap (1-361:1-361) 10 20 30 40 50 60 pF1KB4 MEPPGRRECPFPSWRFPGLLLAAMVLLLYSFSDACEEPPTFEAMELIGKPKPYYEIGERV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_758 MEPPGRRECPFPSWRFPGLLLAAMVLLLYSFSDACEEPPTFEAMELIGKPKPYYEIGERV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 DYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGTYEFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_758 DYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGTYEFG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 YQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_758 YQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 FEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVVENGKQIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_758 FEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVVENGKQIS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 GFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKVSTSSTTKSPASSAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_758 GFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKVSTSSTTKSPASSAS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 GPRPTYKPPVSNYPGYPKPEEGILDSLDVWVIAVIVIAIVVGVAVICVVPYRYLQRRKKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_758 GPRPTYKPPVSNYPGYPKPEEGILDSLDVWVIAVIVIAIVVGVAVICVVPYRYLQRRKKK 310 320 330 340 350 360 370 380 pF1KB4 GKADGGAEYATYQTKSTTPAEQRG : NP_758 GTYLTDETHREVKFTSL 370 >>XP_016856797 (OMIM: 120920,612922) PREDICTED: membrane (378 aa) initn: 2115 init1: 2115 opt: 2430 Z-score: 2358.9 bits: 445.2 E(85289): 1.2e-124 Smith-Waterman score: 2430; 95.0% identity (96.1% similar) in 362 aa overlap (1-361:1-362) 10 20 30 40 50 60 pF1KB4 MEPPGRRECPFPSWRFPGLLLAAMVLLLYSFSDACEEPPTFEAMELIGKPKPYYEIGERV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MEPPGRRECPFPSWRFPGLLLAAMVLLLYSFSDACEEPPTFEAMELIGKPKPYYEIGERV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 DYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGTYEFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGTYEFG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 YQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 FEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVVENGKQIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVVENGKQIS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 GFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKVSTSSTTKSPASSAS :::::::::::::::::::::::::::::::::::::::::::::: :.:: :: : : XP_016 GFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKVLPPSSTKPPALSHS 250 260 270 280 290 300 310 320 330 340 350 pF1KB4 -GPRPTYKPPVSNYPGYPKPEEGILDSLDVWVIAVIVIAIVVGVAVICVVPYRYLQRRKK . : : :.:. ::::::::::::::::::::::::::::::::::::::::::::: XP_016 VSTSSTTKSPASSASGYPKPEEGILDSLDVWVIAVIVIAIVVGVAVICVVPYRYLQRRKK 310 320 330 340 350 360 360 370 380 pF1KB4 KGKADGGAEYATYQTKSTTPAEQRG :: XP_016 KGTYLTDETHREVKFTSL 370 >>XP_016856798 (OMIM: 120920,612922) PREDICTED: membrane (363 aa) initn: 2167 init1: 2167 opt: 2178 Z-score: 2115.4 bits: 400.1 E(85289): 4.4e-111 Smith-Waterman score: 2430; 96.1% identity (96.1% similar) in 361 aa overlap (1-361:1-347) 10 20 30 40 50 60 pF1KB4 MEPPGRRECPFPSWRFPGLLLAAMVLLLYSFSDACEEPPTFEAMELIGKPKPYYEIGERV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MEPPGRRECPFPSWRFPGLLLAAMVLLLYSFSDACEEPPTFEAMELIGKPKPYYEIGERV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 DYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGTYEFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGTYEFG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 YQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 FEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVVENGKQIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVVENGKQIS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 GFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKVSTSSTTKSPASSAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKVSTSSTTKSPASSAS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 GPRPTYKPPVSNYPGYPKPEEGILDSLDVWVIAVIVIAIVVGVAVICVVPYRYLQRRKKK : ::::::::::::::::::::::::::::::::::::::::::::: XP_016 G--------------YPKPEEGILDSLDVWVIAVIVIAIVVGVAVICVVPYRYLQRRKKK 310 320 330 340 370 380 pF1KB4 GKADGGAEYATYQTKSTTPAEQRG : XP_016 GTYLTDETHREVKFTSL 350 360 >>XP_011507866 (OMIM: 120920,612922) PREDICTED: membrane (370 aa) initn: 2167 init1: 2167 opt: 2178 Z-score: 2115.2 bits: 400.1 E(85289): 4.4e-111 Smith-Waterman score: 2578; 96.4% identity (96.4% similar) in 384 aa overlap (1-384:1-370) 10 20 30 40 50 60 pF1KB4 MEPPGRRECPFPSWRFPGLLLAAMVLLLYSFSDACEEPPTFEAMELIGKPKPYYEIGERV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MEPPGRRECPFPSWRFPGLLLAAMVLLLYSFSDACEEPPTFEAMELIGKPKPYYEIGERV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 DYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGTYEFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGTYEFG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 YQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 FEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVVENGKQIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVVENGKQIS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 GFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKVSTSSTTKSPASSAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKVSTSSTTKSPASSAS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 GPRPTYKPPVSNYPGYPKPEEGILDSLDVWVIAVIVIAIVVGVAVICVVPYRYLQRRKKK : ::::::::::::::::::::::::::::::::::::::::::::: XP_011 G--------------YPKPEEGILDSLDVWVIAVIVIAIVVGVAVICVVPYRYLQRRKKK 310 320 330 340 370 380 pF1KB4 GKADGGAEYATYQTKSTTPAEQRG :::::::::::::::::::::::: XP_011 GKADGGAEYATYQTKSTTPAEQRG 350 360 370 >>NP_002380 (OMIM: 120920,612922) membrane cofactor prot (392 aa) initn: 2179 init1: 2115 opt: 2140 Z-score: 2078.1 bits: 393.3 E(85289): 5.2e-109 Smith-Waterman score: 2537; 96.0% identity (96.0% similar) in 376 aa overlap (1-361:1-376) 10 20 30 40 50 60 pF1KB4 MEPPGRRECPFPSWRFPGLLLAAMVLLLYSFSDACEEPPTFEAMELIGKPKPYYEIGERV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MEPPGRRECPFPSWRFPGLLLAAMVLLLYSFSDACEEPPTFEAMELIGKPKPYYEIGERV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 DYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGTYEFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 DYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGTYEFG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 YQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 YQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 FEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVVENGKQIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 FEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVVENGKQIS 190 200 210 220 230 240 250 260 270 280 pF1KB4 GFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKV-------------- :::::::::::::::::::::::::::::::::::::::::::::: NP_002 GFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKVLPPSSTKPPALSHS 250 260 270 280 290 300 290 300 310 320 330 340 pF1KB4 -STSSTTKSPASSASGPRPTYKPPVSNYPGYPKPEEGILDSLDVWVIAVIVIAIVVGVAV ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 VSTSSTTKSPASSASGPRPTYKPPVSNYPGYPKPEEGILDSLDVWVIAVIVIAIVVGVAV 310 320 330 340 350 360 350 360 370 380 pF1KB4 ICVVPYRYLQRRKKKGKADGGAEYATYQTKSTTPAEQRG :::::::::::::::: NP_002 ICVVPYRYLQRRKKKGTYLTDETHREVKFTSL 370 380 390 >>NP_758869 (OMIM: 120920,612922) membrane cofactor prot (399 aa) initn: 2179 init1: 2115 opt: 2140 Z-score: 2078.0 bits: 393.3 E(85289): 5.2e-109 Smith-Waterman score: 2685; 96.2% identity (96.2% similar) in 399 aa overlap (1-384:1-399) 10 20 30 40 50 60 pF1KB4 MEPPGRRECPFPSWRFPGLLLAAMVLLLYSFSDACEEPPTFEAMELIGKPKPYYEIGERV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_758 MEPPGRRECPFPSWRFPGLLLAAMVLLLYSFSDACEEPPTFEAMELIGKPKPYYEIGERV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 DYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGTYEFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_758 DYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGTYEFG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 YQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_758 YQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 FEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVVENGKQIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_758 FEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVVENGKQIS 190 200 210 220 230 240 250 260 270 280 pF1KB4 GFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKV-------------- :::::::::::::::::::::::::::::::::::::::::::::: NP_758 GFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKVLPPSSTKPPALSHS 250 260 270 280 290 300 290 300 310 320 330 340 pF1KB4 -STSSTTKSPASSASGPRPTYKPPVSNYPGYPKPEEGILDSLDVWVIAVIVIAIVVGVAV ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_758 VSTSSTTKSPASSASGPRPTYKPPVSNYPGYPKPEEGILDSLDVWVIAVIVIAIVVGVAV 310 320 330 340 350 360 350 360 370 380 pF1KB4 ICVVPYRYLQRRKKKGKADGGAEYATYQTKSTTPAEQRG ::::::::::::::::::::::::::::::::::::::: NP_758 ICVVPYRYLQRRKKKGKADGGAEYATYQTKSTTPAEQRG 370 380 390 >>NP_758860 (OMIM: 120920,612922) membrane cofactor prot (349 aa) initn: 2336 init1: 2078 opt: 2103 Z-score: 2043.0 bits: 386.6 E(85289): 4.6e-107 Smith-Waterman score: 2310; 95.6% identity (95.6% similar) in 339 aa overlap (1-339:1-324) 10 20 30 40 50 60 pF1KB4 MEPPGRRECPFPSWRFPGLLLAAMVLLLYSFSDACEEPPTFEAMELIGKPKPYYEIGERV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_758 MEPPGRRECPFPSWRFPGLLLAAMVLLLYSFSDACEEPPTFEAMELIGKPKPYYEIGERV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 DYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGTYEFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_758 DYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGTYEFG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 YQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_758 YQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 FEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVVENGKQIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_758 FEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVVENGKQIS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 GFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKVSTSSTTKSPASSAS ::::::::::::::::::::::::::::::::::::::::::::: NP_758 GFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLK--------------- 250 260 270 280 310 320 330 340 350 360 pF1KB4 GPRPTYKPPVSNYPGYPKPEEGILDSLDVWVIAVIVIAIVVGVAVICVVPYRYLQRRKKK ::::::::::::::::::::::::::::::::::::::: NP_758 GPRPTYKPPVSNYPGYPKPEEGILDSLDVWVIAVIVIAIGKQMVELNMPLTRLNQPLQQS 290 300 310 320 330 340 370 380 pF1KB4 GKADGGAEYATYQTKSTTPAEQRG NP_758 REAE >>NP_758862 (OMIM: 120920,612922) membrane cofactor prot (362 aa) initn: 2482 init1: 2078 opt: 2103 Z-score: 2042.8 bits: 386.7 E(85289): 4.8e-107 Smith-Waterman score: 2456; 95.8% identity (95.8% similar) in 361 aa overlap (1-361:1-346) 10 20 30 40 50 60 pF1KB4 MEPPGRRECPFPSWRFPGLLLAAMVLLLYSFSDACEEPPTFEAMELIGKPKPYYEIGERV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_758 MEPPGRRECPFPSWRFPGLLLAAMVLLLYSFSDACEEPPTFEAMELIGKPKPYYEIGERV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 DYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGTYEFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_758 DYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGTYEFG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 YQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_758 YQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 FEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVVENGKQIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_758 FEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVVENGKQIS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 GFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKVSTSSTTKSPASSAS ::::::::::::::::::::::::::::::::::::::::::::: NP_758 GFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLK--------------- 250 260 270 280 310 320 330 340 350 360 pF1KB4 GPRPTYKPPVSNYPGYPKPEEGILDSLDVWVIAVIVIAIVVGVAVICVVPYRYLQRRKKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_758 GPRPTYKPPVSNYPGYPKPEEGILDSLDVWVIAVIVIAIVVGVAVICVVPYRYLQRRKKK 290 300 310 320 330 340 370 380 pF1KB4 GKADGGAEYATYQTKSTTPAEQRG : NP_758 GTYLTDETHREVKFTSL 350 360 384 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 03:05:59 2016 done: Fri Nov 4 03:06:00 2016 Total Scan time: 8.650 Total Display time: 0.040 Function used was FASTA [36.3.4 Apr, 2011]