FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB4637, 300 aa 1>>>pF1KB4637 300 - 300 aa - 300 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.7072+/-0.000713; mu= 10.4802+/- 0.043 mean_var=116.7727+/-22.883, 0's: 0 Z-trim(113.8): 21 B-trim: 0 in 0/51 Lambda= 0.118687 statistics sampled from 14368 (14383) to 14368 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.787), E-opt: 0.2 (0.442), width: 16 Scan time: 2.450 The best scores are: opt bits E(32554) CCDS85.1 PHF13 gene_id:148479|Hs108|chr1 ( 300) 2093 368.5 3.4e-102 CCDS67144.1 PHF23 gene_id:79142|Hs108|chr17 ( 336) 434 84.5 1.2e-16 CCDS67143.1 PHF23 gene_id:79142|Hs108|chr17 ( 399) 434 84.5 1.4e-16 CCDS42250.1 PHF23 gene_id:79142|Hs108|chr17 ( 403) 434 84.5 1.4e-16 >>CCDS85.1 PHF13 gene_id:148479|Hs108|chr1 (300 aa) initn: 2093 init1: 2093 opt: 2093 Z-score: 1948.1 bits: 368.5 E(32554): 3.4e-102 Smith-Waterman score: 2093; 100.0% identity (100.0% similar) in 300 aa overlap (1-300:1-300) 10 20 30 40 50 60 pF1KB4 MDSDSCAAAFHPEEYSPSCKRRRTVEDFNKFCTFVLAYAGYIPYPKEELPLRSSPSPANS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS85 MDSDSCAAAFHPEEYSPSCKRRRTVEDFNKFCTFVLAYAGYIPYPKEELPLRSSPSPANS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 TAGTIDSDGWDAGFSDIASSVPLPVSDRCFSHLQPTLLQRAKPSNFLLDRKKTDKLKKKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS85 TAGTIDSDGWDAGFSDIASSVPLPVSDRCFSHLQPTLLQRAKPSNFLLDRKKTDKLKKKK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 KRKRRDSDAPGKEGYRGGLLKLEAADPYVETPTSPTLQDIPQAPSDPCSGWDSDTPSSGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS85 KRKRRDSDAPGKEGYRGGLLKLEAADPYVETPTSPTLQDIPQAPSDPCSGWDSDTPSSGS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 CATVSPDQVKEIKTEGKRTIVRQGKQVVFRDEDSTGNDEDIMVDSDDDSWDLVTCFCMKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS85 CATVSPDQVKEIKTEGKRTIVRQGKQVVFRDEDSTGNDEDIMVDSDDDSWDLVTCFCMKP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 FAGRPMIECNECHTWIHLSCAKIRKSNVPEVFVCQKCRDSKFDIRRSNRSRTGSRKLFLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS85 FAGRPMIECNECHTWIHLSCAKIRKSNVPEVFVCQKCRDSKFDIRRSNRSRTGSRKLFLD 250 260 270 280 290 300 >>CCDS67144.1 PHF23 gene_id:79142|Hs108|chr17 (336 aa) initn: 585 init1: 395 opt: 434 Z-score: 412.2 bits: 84.5 E(32554): 1.2e-16 Smith-Waterman score: 569; 36.8% identity (56.1% similar) in 321 aa overlap (10-286:17-326) 10 20 30 40 50 pF1KB4 MDSDSCAAAFHPEEYSPSCKRRRTVEDFNKFCTFVLAYAGYIPYPKEELPLRS ..:: : :::::.:::::::.:::::::::: :..: : . CCDS67 MLEAMAEPSPEDPPPTLKPETQPPE-KRRRTIEDFNKFCSFVLAYAGYIP-PSKEAPDSA 10 20 30 40 50 60 70 80 90 pF1KB4 SPSPANSTAGTI-DSDGWDAG--FSDI---------ASSVPLPVSDRCFSH--------- . . .. : :: .. .: :. .:.:.:. .:: CCDS67 TLLEKMKLKDSLFDLDGPKVASPLSPTSLTHTSRPPAALTPVPLSQGDLSHPPRKKDRKN 60 70 80 90 100 110 100 110 120 130 pF1KB4 --LQPT------LLQRAKPSNFLLDRKKTDKLKKKKKRKRRDSD------APGKEGYRGG : : .:.: .:. : .: ...::.:::: . .. :: . CCDS67 RKLGPGAGAGFGVLRRPRPTP--GDGEKRSRIKKSKKRKLKKAERGDRLPPPGPPQAPPS 120 130 140 150 160 170 140 150 160 170 180 190 pF1KB4 LLKLEAADPYVETPTSPTLQDI--PQAPSDPCSGWDSDTPSSGSCATVSPDQVKEIKTEG : . : . . .:: : ..: ::: :. : .:. CCDS67 DTDSEEEEEEEEEEEEEEMATVVGGEAPV-PVLPTPPEAPRPP--ATVHPEGVPPADSES 180 190 200 210 220 230 200 210 220 230 240 pF1KB4 KRTIVRQGKQVVFRDEDSTGN-------DEDIMVDSDDDSWDLVTCFCMKPFAGRPMIEC :.. :. . .: :.... ::::::.: ::::::.::.: ::::::::::: CCDS67 KEV----GSTETSQDGDASSSEGEMRVMDEDIMVESGDDSWDLITCYCRKPFAGRPMIEC 240 250 260 270 280 250 260 270 280 290 300 pF1KB4 NECHTWIHLSCAKIRKSNVPEVFVCQKCRDSKFDIRRSNRSRTGSRKLFLD . : ::::::::::.:.:::. : ::::.. . . :: CCDS67 SLCGTWIHLSCAKIKKTNVPDFFYCQKCKELRPEARRLGGPPKSGEP 290 300 310 320 330 >>CCDS67143.1 PHF23 gene_id:79142|Hs108|chr17 (399 aa) initn: 667 init1: 395 opt: 434 Z-score: 411.1 bits: 84.5 E(32554): 1.4e-16 Smith-Waterman score: 435; 33.7% identity (53.9% similar) in 258 aa overlap (39-286:158-389) 10 20 30 40 50 60 pF1KB4 AFHPEEYSPSCKRRRTVEDFNKFCTFVLAYAGYIPYPKEELPLRSSPSPANSTAGTIDSD :. : : . : : . . . CCDS67 KLKDSLFDLDGPKVASPLSPTSLTHTSRPPAALTPVPLSQGDLSHPPRKKDRKNRKL-GP 130 140 150 160 170 180 70 80 90 100 110 120 pF1KB4 GWDAGFSDIASSVPLPVSDRCFSHLQPTLLQRAKPSNFLLDRKKTDKLKKKKKRKRRDSD : :::. . : : . . :... . .. : . .. :.: . :: CCDS67 GAGAGFGVLRRPRPTPGDGEKRSRIKKSKKRKLKKA------ERGDRLPPPGPPQAPPSD 190 200 210 220 230 240 130 140 150 160 170 180 pF1KB4 APGKEGYRGGLLKLEAADPYV---ETPTSPTLQDIPQAPSDPCSGWDSDTPSSGSCATVS . ..: . . : : :.:. :.: :.:: : ::: CCDS67 TDSEEEEEEEEEEEEEEMATVVGGEAPV-PVLPTPPEAPRPP--------------ATVH 250 260 270 280 190 200 210 220 230 pF1KB4 PDQVKEIKTEGKRTIVRQGKQVVFRDEDSTGN-------DEDIMVDSDDDSWDLVTCFCM :. : .:.:.. :. . .: :.... ::::::.: ::::::.::.: CCDS67 PEGVPPADSESKEV----GSTETSQDGDASSSEGEMRVMDEDIMVESGDDSWDLITCYCR 290 300 310 320 330 340 240 250 260 270 280 290 pF1KB4 KPFAGRPMIECNECHTWIHLSCAKIRKSNVPEVFVCQKCRDSKFDIRRSNRSRTGSRKLF :::::::::::. : ::::::::::.:.:::. : ::::.. . . :: CCDS67 KPFAGRPMIECSLCGTWIHLSCAKIKKTNVPDFFYCQKCKELRPEARRLGGPPKSGEP 350 360 370 380 390 300 pF1KB4 LD >>CCDS42250.1 PHF23 gene_id:79142|Hs108|chr17 (403 aa) initn: 641 init1: 395 opt: 434 Z-score: 411.1 bits: 84.5 E(32554): 1.4e-16 Smith-Waterman score: 435; 33.7% identity (53.9% similar) in 258 aa overlap (39-286:162-393) 10 20 30 40 50 60 pF1KB4 AFHPEEYSPSCKRRRTVEDFNKFCTFVLAYAGYIPYPKEELPLRSSPSPANSTAGTIDSD :. : : . : : . . . CCDS42 KLKDSLFDLDGPKVASPLSPTSLTHTSRPPAALTPVPLSQGDLSHPPRKKDRKNRKL-GP 140 150 160 170 180 190 70 80 90 100 110 120 pF1KB4 GWDAGFSDIASSVPLPVSDRCFSHLQPTLLQRAKPSNFLLDRKKTDKLKKKKKRKRRDSD : :::. . : : . . :... . .. : . .. :.: . :: CCDS42 GAGAGFGVLRRPRPTPGDGEKRSRIKKSKKRKLKKA------ERGDRLPPPGPPQAPPSD 200 210 220 230 240 130 140 150 160 170 180 pF1KB4 APGKEGYRGGLLKLEAADPYV---ETPTSPTLQDIPQAPSDPCSGWDSDTPSSGSCATVS . ..: . . : : :.:. :.: :.:: : ::: CCDS42 TDSEEEEEEEEEEEEEEMATVVGGEAPV-PVLPTPPEAPRPP--------------ATVH 250 260 270 280 190 200 210 220 230 pF1KB4 PDQVKEIKTEGKRTIVRQGKQVVFRDEDSTGN-------DEDIMVDSDDDSWDLVTCFCM :. : .:.:.. :. . .: :.... ::::::.: ::::::.::.: CCDS42 PEGVPPADSESKEV----GSTETSQDGDASSSEGEMRVMDEDIMVESGDDSWDLITCYCR 290 300 310 320 330 340 240 250 260 270 280 290 pF1KB4 KPFAGRPMIECNECHTWIHLSCAKIRKSNVPEVFVCQKCRDSKFDIRRSNRSRTGSRKLF :::::::::::. : ::::::::::.:.:::. : ::::.. . . :: CCDS42 KPFAGRPMIECSLCGTWIHLSCAKIKKTNVPDFFYCQKCKELRPEARRLGGPPKSGEP 350 360 370 380 390 400 300 pF1KB4 LD 300 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 03:07:17 2016 done: Fri Nov 4 03:07:17 2016 Total Scan time: 2.450 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]