FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB4666, 68 aa 1>>>pF1KB4666 68 - 68 aa - 68 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.4705+/-0.000259; mu= 10.9353+/- 0.016 mean_var=46.8440+/- 9.270, 0's: 0 Z-trim(120.0): 30 B-trim: 75 in 1/54 Lambda= 0.187390 statistics sampled from 34636 (34667) to 34636 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.808), E-opt: 0.2 (0.406), width: 16 Scan time: 3.900 The best scores are: opt bits E(85289) NP_001017998 (OMIM: 604389) guanine nucleotide-bin ( 68) 436 124.1 1.7e-29 NP_001185593 (OMIM: 604389) guanine nucleotide-bin ( 68) 436 124.1 1.7e-29 NP_005265 (OMIM: 600874) guanine nucleotide-bindin ( 68) 264 77.6 1.7e-15 NP_443079 (OMIM: 604430) guanine nucleotide-bindin ( 68) 249 73.6 2.8e-14 XP_016882095 (OMIM: 604430) PREDICTED: guanine nuc ( 68) 249 73.6 2.8e-14 XP_016876866 (OMIM: 606981) PREDICTED: guanine nuc ( 71) 228 67.9 1.5e-12 NP_001230702 (OMIM: 606981) guanine nucleotide-bin ( 71) 228 67.9 1.5e-12 XP_011535148 (OMIM: 606981) PREDICTED: guanine nuc ( 71) 228 67.9 1.5e-12 XP_016876865 (OMIM: 606981) PREDICTED: guanine nuc ( 71) 228 67.9 1.5e-12 NP_001230703 (OMIM: 606981) guanine nucleotide-bin ( 71) 228 67.9 1.5e-12 XP_006720236 (OMIM: 606981) PREDICTED: guanine nuc ( 71) 228 67.9 1.5e-12 NP_444292 (OMIM: 606981) guanine nucleotide-bindin ( 71) 228 67.9 1.5e-12 NP_061329 (OMIM: 615405) guanine nucleotide-bindin ( 72) 222 66.3 4.7e-12 XP_016857300 (OMIM: 615405) PREDICTED: guanine nuc ( 72) 222 66.3 4.7e-12 XP_016857299 (OMIM: 615405) PREDICTED: guanine nuc ( 72) 222 66.3 4.7e-12 XP_016857298 (OMIM: 615405) PREDICTED: guanine nuc ( 72) 222 66.3 4.7e-12 XP_006718563 (OMIM: 608941) PREDICTED: guanine nuc ( 75) 218 65.2 1e-11 NP_036334 (OMIM: 608941) guanine nucleotide-bindin ( 75) 218 65.2 1e-11 NP_001092191 (OMIM: 604388) guanine nucleotide-bin ( 75) 204 61.4 1.4e-10 NP_004476 (OMIM: 604388) guanine nucleotide-bindin ( 75) 204 61.4 1.4e-10 NP_001092192 (OMIM: 604388) guanine nucleotide-bin ( 75) 204 61.4 1.4e-10 XP_006711824 (OMIM: 604388) PREDICTED: guanine nuc ( 75) 204 61.4 1.4e-10 XP_011542469 (OMIM: 604388) PREDICTED: guanine nuc ( 75) 204 61.4 1.4e-10 NP_001185683 (OMIM: 139391) guanine nucleotide-bin ( 69) 147 46.0 5.7e-06 NP_001185685 (OMIM: 139391) guanine nucleotide-bin ( 69) 147 46.0 5.7e-06 NP_001185684 (OMIM: 139391) guanine nucleotide-bin ( 69) 147 46.0 5.7e-06 NP_113686 (OMIM: 139391) guanine nucleotide-bindin ( 69) 147 46.0 5.7e-06 NP_004117 (OMIM: 604390) guanine nucleotide-bindin ( 73) 143 44.9 1.3e-05 NP_068774 (OMIM: 189970) guanine nucleotide-bindin ( 74) 129 41.1 0.00018 NP_001316355 (OMIM: 189970) guanine nucleotide-bin ( 74) 129 41.1 0.00018 >>NP_001017998 (OMIM: 604389) guanine nucleotide-binding (68 aa) initn: 436 init1: 436 opt: 436 Z-score: 650.5 bits: 124.1 E(85289): 1.7e-29 Smith-Waterman score: 436; 100.0% identity (100.0% similar) in 68 aa overlap (1-68:1-68) 10 20 30 40 50 60 pF1KB4 MSSGASASALQRLVEQLKLEAGVERIKVSQAAAELQQYCMQNACKDALLVGVPAGSNPFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSSGASASALQRLVEQLKLEAGVERIKVSQAAAELQQYCMQNACKDALLVGVPAGSNPFR 10 20 30 40 50 60 pF1KB4 EPRSCALL :::::::: NP_001 EPRSCALL >>NP_001185593 (OMIM: 604389) guanine nucleotide-binding (68 aa) initn: 436 init1: 436 opt: 436 Z-score: 650.5 bits: 124.1 E(85289): 1.7e-29 Smith-Waterman score: 436; 100.0% identity (100.0% similar) in 68 aa overlap (1-68:1-68) 10 20 30 40 50 60 pF1KB4 MSSGASASALQRLVEQLKLEAGVERIKVSQAAAELQQYCMQNACKDALLVGVPAGSNPFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSSGASASALQRLVEQLKLEAGVERIKVSQAAAELQQYCMQNACKDALLVGVPAGSNPFR 10 20 30 40 50 60 pF1KB4 EPRSCALL :::::::: NP_001 EPRSCALL >>NP_005265 (OMIM: 600874) guanine nucleotide-binding pr (68 aa) initn: 280 init1: 264 opt: 264 Z-score: 399.2 bits: 77.6 E(85289): 1.7e-15 Smith-Waterman score: 264; 52.9% identity (91.2% similar) in 68 aa overlap (1-68:1-68) 10 20 30 40 50 60 pF1KB4 MSSGASASALQRLVEQLKLEAGVERIKVSQAAAELQQYCMQNACKDALLVGVPAGSNPFR ::...:..:....:.::.::::..:.:::::::.:.:.:.::: .: ::.:: ...:::: NP_005 MSGSSSVAAMKKVVQQLRLEAGLNRVKVSQAAADLKQFCLQNAQHDPLLTGVSSSTNPFR 10 20 30 40 50 60 pF1KB4 EPRSCALL . :..: NP_005 PQKVCSFL >>NP_443079 (OMIM: 604430) guanine nucleotide-binding pr (68 aa) initn: 267 init1: 249 opt: 249 Z-score: 377.3 bits: 73.6 E(85289): 2.8e-14 Smith-Waterman score: 249; 52.9% identity (82.4% similar) in 68 aa overlap (1-68:1-68) 10 20 30 40 50 60 pF1KB4 MSSGASASALQRLVEQLKLEAGVERIKVSQAAAELQQYCMQNACKDALLVGVPAGSNPFR ::. . . ..:::::..:::.::::::.::..:..:: :.: .: :::::::. :::. NP_443 MSATNNIAQARKLVEQLRIEAGIERIKVSKAASDLMSYCEQHARNDPLLVGVPASENPFK 10 20 30 40 50 60 pF1KB4 EPRSCALL . . : .: NP_443 DKKPCIIL >>XP_016882095 (OMIM: 604430) PREDICTED: guanine nucleot (68 aa) initn: 267 init1: 249 opt: 249 Z-score: 377.3 bits: 73.6 E(85289): 2.8e-14 Smith-Waterman score: 249; 52.9% identity (82.4% similar) in 68 aa overlap (1-68:1-68) 10 20 30 40 50 60 pF1KB4 MSSGASASALQRLVEQLKLEAGVERIKVSQAAAELQQYCMQNACKDALLVGVPAGSNPFR ::. . . ..:::::..:::.::::::.::..:..:: :.: .: :::::::. :::. XP_016 MSATNNIAQARKLVEQLRIEAGIERIKVSKAASDLMSYCEQHARNDPLLVGVPASENPFK 10 20 30 40 50 60 pF1KB4 EPRSCALL . . : .: XP_016 DKKPCIIL >>XP_016876866 (OMIM: 606981) PREDICTED: guanine nucleot (71 aa) initn: 230 init1: 212 opt: 228 Z-score: 346.3 bits: 67.9 E(85289): 1.5e-12 Smith-Waterman score: 228; 54.9% identity (78.9% similar) in 71 aa overlap (1-68:1-71) 10 20 30 40 50 pF1KB4 MSSGASASALQ--RLVEQLKLEAGVERIKVSQAAAELQQYCMQNACKDALLVGVPAGSNP :.:. .:: : .::::::.::...:::::.:::.:. :: .: .: ::. :::. :: XP_016 MASNNTASIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENP 10 20 30 40 50 60 60 pF1KB4 FREPRS-CALL ::: . ::.: XP_016 FREKKFFCAIL 70 >>NP_001230702 (OMIM: 606981) guanine nucleotide-binding (71 aa) initn: 230 init1: 212 opt: 228 Z-score: 346.3 bits: 67.9 E(85289): 1.5e-12 Smith-Waterman score: 228; 54.9% identity (78.9% similar) in 71 aa overlap (1-68:1-71) 10 20 30 40 50 pF1KB4 MSSGASASALQ--RLVEQLKLEAGVERIKVSQAAAELQQYCMQNACKDALLVGVPAGSNP :.:. .:: : .::::::.::...:::::.:::.:. :: .: .: ::. :::. :: NP_001 MASNNTASIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENP 10 20 30 40 50 60 60 pF1KB4 FREPRS-CALL ::: . ::.: NP_001 FREKKFFCAIL 70 >>XP_011535148 (OMIM: 606981) PREDICTED: guanine nucleot (71 aa) initn: 230 init1: 212 opt: 228 Z-score: 346.3 bits: 67.9 E(85289): 1.5e-12 Smith-Waterman score: 228; 54.9% identity (78.9% similar) in 71 aa overlap (1-68:1-71) 10 20 30 40 50 pF1KB4 MSSGASASALQ--RLVEQLKLEAGVERIKVSQAAAELQQYCMQNACKDALLVGVPAGSNP :.:. .:: : .::::::.::...:::::.:::.:. :: .: .: ::. :::. :: XP_011 MASNNTASIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENP 10 20 30 40 50 60 60 pF1KB4 FREPRS-CALL ::: . ::.: XP_011 FREKKFFCAIL 70 >>XP_016876865 (OMIM: 606981) PREDICTED: guanine nucleot (71 aa) initn: 230 init1: 212 opt: 228 Z-score: 346.3 bits: 67.9 E(85289): 1.5e-12 Smith-Waterman score: 228; 54.9% identity (78.9% similar) in 71 aa overlap (1-68:1-71) 10 20 30 40 50 pF1KB4 MSSGASASALQ--RLVEQLKLEAGVERIKVSQAAAELQQYCMQNACKDALLVGVPAGSNP :.:. .:: : .::::::.::...:::::.:::.:. :: .: .: ::. :::. :: XP_016 MASNNTASIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENP 10 20 30 40 50 60 60 pF1KB4 FREPRS-CALL ::: . ::.: XP_016 FREKKFFCAIL 70 >>NP_001230703 (OMIM: 606981) guanine nucleotide-binding (71 aa) initn: 230 init1: 212 opt: 228 Z-score: 346.3 bits: 67.9 E(85289): 1.5e-12 Smith-Waterman score: 228; 54.9% identity (78.9% similar) in 71 aa overlap (1-68:1-71) 10 20 30 40 50 pF1KB4 MSSGASASALQ--RLVEQLKLEAGVERIKVSQAAAELQQYCMQNACKDALLVGVPAGSNP :.:. .:: : .::::::.::...:::::.:::.:. :: .: .: ::. :::. :: NP_001 MASNNTASIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENP 10 20 30 40 50 60 60 pF1KB4 FREPRS-CALL ::: . ::.: NP_001 FREKKFFCAIL 70 68 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 03:08:25 2016 done: Fri Nov 4 03:08:26 2016 Total Scan time: 3.900 Total Display time: -0.040 Function used was FASTA [36.3.4 Apr, 2011]