FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB4670, 401 aa 1>>>pF1KB4670 401 - 401 aa - 401 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.7542+/-0.00079; mu= 12.3642+/- 0.049 mean_var=145.6206+/-30.389, 0's: 0 Z-trim(112.9): 51 B-trim: 766 in 1/51 Lambda= 0.106283 statistics sampled from 13561 (13612) to 13561 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.763), E-opt: 0.2 (0.418), width: 16 Scan time: 3.280 The best scores are: opt bits E(32554) CCDS45217.1 MEIS2 gene_id:4212|Hs108|chr15 ( 401) 2817 443.2 2e-124 CCDS45218.1 MEIS2 gene_id:4212|Hs108|chr15 ( 394) 2744 432.0 4.6e-121 CCDS45219.1 MEIS2 gene_id:4212|Hs108|chr15 ( 388) 2720 428.3 5.8e-120 CCDS10044.1 MEIS2 gene_id:4212|Hs108|chr15 ( 477) 2679 422.1 5.2e-118 CCDS42014.1 MEIS2 gene_id:4212|Hs108|chr15 ( 381) 2647 417.1 1.3e-116 CCDS10045.1 MEIS2 gene_id:4212|Hs108|chr15 ( 470) 2606 410.9 1.2e-114 CCDS45220.1 MEIS2 gene_id:4212|Hs108|chr15 ( 306) 2090 331.6 5.9e-91 CCDS46309.1 MEIS1 gene_id:4211|Hs108|chr2 ( 390) 2074 329.3 3.8e-90 CCDS74406.1 MEIS3 gene_id:56917|Hs108|chr19 ( 375) 1599 256.4 3.1e-68 CCDS33064.1 MEIS3 gene_id:56917|Hs108|chr19 ( 421) 1229 199.7 4.1e-51 CCDS46132.1 MEIS3 gene_id:56917|Hs108|chr19 ( 358) 913 151.2 1.4e-36 CCDS13692.1 PKNOX1 gene_id:5316|Hs108|chr21 ( 436) 436 78.2 1.7e-14 CCDS41730.1 PKNOX2 gene_id:63876|Hs108|chr11 ( 472) 380 69.6 6.8e-12 CCDS68211.1 PKNOX1 gene_id:5316|Hs108|chr21 ( 319) 355 65.6 7.3e-11 >>CCDS45217.1 MEIS2 gene_id:4212|Hs108|chr15 (401 aa) initn: 2817 init1: 2817 opt: 2817 Z-score: 2347.4 bits: 443.2 E(32554): 2e-124 Smith-Waterman score: 2817; 100.0% identity (100.0% similar) in 401 aa overlap (1-401:1-401) 10 20 30 40 50 60 pF1KB4 MAQRYDELPHYGGMDGVGVPASMYGDPHAPRPIPPVHHLNHGPPLHATQHYGAHAPHPNV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 MAQRYDELPHYGGMDGVGVPASMYGDPHAPRPIPPVHHLNHGPPLHATQHYGAHAPHPNV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 MPASMGSAVNDALKRDKDAIYGHPLFPLLALVFEKCELATCTPREPGVAGGDVCSSDSFN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 MPASMGSAVNDALKRDKDAIYGHPLFPLLALVFEKCELATCTPREPGVAGGDVCSSDSFN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 EDIAVFAKQVRAEKPLFSSNPELDNLMIQAIQVLRFHLLELEKVHELCDNFCHRYISCLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 EDIAVFAKQVRAEKPLFSSNPELDNLMIQAIQVLRFHLLELEKVHELCDNFCHRYISCLK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 GKMPIDLVIDERDGSSKSDHEELSGSSTNLADHNPSSWRDHDDATSTHSAGTPGPSSGGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 GKMPIDLVIDERDGSSKSDHEELSGSSTNLADHNPSSWRDHDDATSTHSAGTPGPSSGGH 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 ASQSGDNSSEQGDGLDNSVASPGTGDDDDPDKDKKRQKKRGIFPKVATNIMRAWLFQHLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 ASQSGDNSSEQGDGLDNSVASPGTGDDDDPDKDKKRQKKRGIFPKVATNIMRAWLFQHLT 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 HPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRAGFLLDPSVSQGAAYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 HPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRAGFLLDPSVSQGAAYS 310 320 330 340 350 360 370 380 390 400 pF1KB4 PEGQPMGSFVLDGQQHMGIRPAGPMSGMGMNMGMDGQWHYM ::::::::::::::::::::::::::::::::::::::::: CCDS45 PEGQPMGSFVLDGQQHMGIRPAGPMSGMGMNMGMDGQWHYM 370 380 390 400 >>CCDS45218.1 MEIS2 gene_id:4212|Hs108|chr15 (394 aa) initn: 2407 init1: 2407 opt: 2744 Z-score: 2287.0 bits: 432.0 E(32554): 4.6e-121 Smith-Waterman score: 2744; 98.3% identity (98.3% similar) in 401 aa overlap (1-401:1-394) 10 20 30 40 50 60 pF1KB4 MAQRYDELPHYGGMDGVGVPASMYGDPHAPRPIPPVHHLNHGPPLHATQHYGAHAPHPNV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 MAQRYDELPHYGGMDGVGVPASMYGDPHAPRPIPPVHHLNHGPPLHATQHYGAHAPHPNV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 MPASMGSAVNDALKRDKDAIYGHPLFPLLALVFEKCELATCTPREPGVAGGDVCSSDSFN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 MPASMGSAVNDALKRDKDAIYGHPLFPLLALVFEKCELATCTPREPGVAGGDVCSSDSFN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 EDIAVFAKQVRAEKPLFSSNPELDNLMIQAIQVLRFHLLELEKVHELCDNFCHRYISCLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 EDIAVFAKQVRAEKPLFSSNPELDNLMIQAIQVLRFHLLELEKVHELCDNFCHRYISCLK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 GKMPIDLVIDERDGSSKSDHEELSGSSTNLADHNPSSWRDHDDATSTHSAGTPGPSSGGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 GKMPIDLVIDERDGSSKSDHEELSGSSTNLADHNPSSWRDHDDATSTHSAGTPGPSSGGH 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 ASQSGDNSSEQGDGLDNSVASPGTGDDDDPDKDKKRQKKRGIFPKVATNIMRAWLFQHLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 ASQSGDNSSEQGDGLDNSVASPGTGDDDDPDKDKKRQKKRGIFPKVATNIMRAWLFQHLT 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 HPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRAGFLLDPSVSQGAAYS ::::::::::::::::::::::::::::::::::::::::::::: :::::::: CCDS45 HPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRA-------VSQGAAYS 310 320 330 340 350 370 380 390 400 pF1KB4 PEGQPMGSFVLDGQQHMGIRPAGPMSGMGMNMGMDGQWHYM ::::::::::::::::::::::::::::::::::::::::: CCDS45 PEGQPMGSFVLDGQQHMGIRPAGPMSGMGMNMGMDGQWHYM 360 370 380 390 >>CCDS45219.1 MEIS2 gene_id:4212|Hs108|chr15 (388 aa) initn: 2720 init1: 2720 opt: 2720 Z-score: 2267.2 bits: 428.3 E(32554): 5.8e-120 Smith-Waterman score: 2720; 100.0% identity (100.0% similar) in 388 aa overlap (14-401:1-388) 10 20 30 40 50 60 pF1KB4 MAQRYDELPHYGGMDGVGVPASMYGDPHAPRPIPPVHHLNHGPPLHATQHYGAHAPHPNV ::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 MDGVGVPASMYGDPHAPRPIPPVHHLNHGPPLHATQHYGAHAPHPNV 10 20 30 40 70 80 90 100 110 120 pF1KB4 MPASMGSAVNDALKRDKDAIYGHPLFPLLALVFEKCELATCTPREPGVAGGDVCSSDSFN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 MPASMGSAVNDALKRDKDAIYGHPLFPLLALVFEKCELATCTPREPGVAGGDVCSSDSFN 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB4 EDIAVFAKQVRAEKPLFSSNPELDNLMIQAIQVLRFHLLELEKVHELCDNFCHRYISCLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 EDIAVFAKQVRAEKPLFSSNPELDNLMIQAIQVLRFHLLELEKVHELCDNFCHRYISCLK 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB4 GKMPIDLVIDERDGSSKSDHEELSGSSTNLADHNPSSWRDHDDATSTHSAGTPGPSSGGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 GKMPIDLVIDERDGSSKSDHEELSGSSTNLADHNPSSWRDHDDATSTHSAGTPGPSSGGH 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB4 ASQSGDNSSEQGDGLDNSVASPGTGDDDDPDKDKKRQKKRGIFPKVATNIMRAWLFQHLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 ASQSGDNSSEQGDGLDNSVASPGTGDDDDPDKDKKRQKKRGIFPKVATNIMRAWLFQHLT 230 240 250 260 270 280 310 320 330 340 350 360 pF1KB4 HPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRAGFLLDPSVSQGAAYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 HPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRAGFLLDPSVSQGAAYS 290 300 310 320 330 340 370 380 390 400 pF1KB4 PEGQPMGSFVLDGQQHMGIRPAGPMSGMGMNMGMDGQWHYM ::::::::::::::::::::::::::::::::::::::::: CCDS45 PEGQPMGSFVLDGQQHMGIRPAGPMSGMGMNMGMDGQWHYM 350 360 370 380 >>CCDS10044.1 MEIS2 gene_id:4212|Hs108|chr15 (477 aa) initn: 2704 init1: 2674 opt: 2679 Z-score: 2232.1 bits: 422.1 E(32554): 5.2e-118 Smith-Waterman score: 2679; 97.2% identity (97.5% similar) in 400 aa overlap (1-394:1-400) 10 20 30 40 50 60 pF1KB4 MAQRYDELPHYGGMDGVGVPASMYGDPHAPRPIPPVHHLNHGPPLHATQHYGAHAPHPNV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 MAQRYDELPHYGGMDGVGVPASMYGDPHAPRPIPPVHHLNHGPPLHATQHYGAHAPHPNV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 MPASMGSAVNDALKRDKDAIYGHPLFPLLALVFEKCELATCTPREPGVAGGDVCSSDSFN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 MPASMGSAVNDALKRDKDAIYGHPLFPLLALVFEKCELATCTPREPGVAGGDVCSSDSFN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 EDIAVFAKQVRAEKPLFSSNPELDNLMIQAIQVLRFHLLELEKVHELCDNFCHRYISCLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 EDIAVFAKQVRAEKPLFSSNPELDNLMIQAIQVLRFHLLELEKVHELCDNFCHRYISCLK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 GKMPIDLVIDERDGSSKSDHEELSGSSTNLADHNPSSWRDHDDATSTHSAGTPGPSSGGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 GKMPIDLVIDERDGSSKSDHEELSGSSTNLADHNPSSWRDHDDATSTHSAGTPGPSSGGH 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 ASQSGDNSSEQGDGLDNSVASPGTGDDDDPDKDKKRQKKRGIFPKVATNIMRAWLFQHLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 ASQSGDNSSEQGDGLDNSVASPGTGDDDDPDKDKKRQKKRGIFPKVATNIMRAWLFQHLT 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 HPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRAGFLLDPSVSQGAAYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 HPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRAGFLLDPSVSQGAAYS 310 320 330 340 350 360 370 380 390 400 pF1KB4 PEGQPMGSFVLDGQQHMGIRPAG--PMSG----MGMNMGMDGQWHYM ::::::::::::::::::::::: : : .: ::: CCDS10 PEGQPMGSFVLDGQQHMGIRPAGLQSMPGDYVSQGGPMGMSMAQPSYTPPQMTPHPTQLR 370 380 390 400 410 420 CCDS10 HGPPMHSYLPSHPHHPAMMMHGGPPTHPGMTMSAQSPTMLNSVDPNVGGQVMDIHAQ 430 440 450 460 470 >>CCDS42014.1 MEIS2 gene_id:4212|Hs108|chr15 (381 aa) initn: 2310 init1: 2310 opt: 2647 Z-score: 2206.8 bits: 417.1 E(32554): 1.3e-116 Smith-Waterman score: 2647; 98.2% identity (98.2% similar) in 388 aa overlap (14-401:1-381) 10 20 30 40 50 60 pF1KB4 MAQRYDELPHYGGMDGVGVPASMYGDPHAPRPIPPVHHLNHGPPLHATQHYGAHAPHPNV ::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 MDGVGVPASMYGDPHAPRPIPPVHHLNHGPPLHATQHYGAHAPHPNV 10 20 30 40 70 80 90 100 110 120 pF1KB4 MPASMGSAVNDALKRDKDAIYGHPLFPLLALVFEKCELATCTPREPGVAGGDVCSSDSFN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 MPASMGSAVNDALKRDKDAIYGHPLFPLLALVFEKCELATCTPREPGVAGGDVCSSDSFN 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB4 EDIAVFAKQVRAEKPLFSSNPELDNLMIQAIQVLRFHLLELEKVHELCDNFCHRYISCLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 EDIAVFAKQVRAEKPLFSSNPELDNLMIQAIQVLRFHLLELEKVHELCDNFCHRYISCLK 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB4 GKMPIDLVIDERDGSSKSDHEELSGSSTNLADHNPSSWRDHDDATSTHSAGTPGPSSGGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 GKMPIDLVIDERDGSSKSDHEELSGSSTNLADHNPSSWRDHDDATSTHSAGTPGPSSGGH 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB4 ASQSGDNSSEQGDGLDNSVASPGTGDDDDPDKDKKRQKKRGIFPKVATNIMRAWLFQHLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 ASQSGDNSSEQGDGLDNSVASPGTGDDDDPDKDKKRQKKRGIFPKVATNIMRAWLFQHLT 230 240 250 260 270 280 310 320 330 340 350 360 pF1KB4 HPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRAGFLLDPSVSQGAAYS ::::::::::::::::::::::::::::::::::::::::::::: :::::::: CCDS42 HPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRA-------VSQGAAYS 290 300 310 320 330 340 370 380 390 400 pF1KB4 PEGQPMGSFVLDGQQHMGIRPAGPMSGMGMNMGMDGQWHYM ::::::::::::::::::::::::::::::::::::::::: CCDS42 PEGQPMGSFVLDGQQHMGIRPAGPMSGMGMNMGMDGQWHYM 350 360 370 380 >>CCDS10045.1 MEIS2 gene_id:4212|Hs108|chr15 (470 aa) initn: 2611 init1: 2407 opt: 2606 Z-score: 2171.7 bits: 410.9 E(32554): 1.2e-114 Smith-Waterman score: 2606; 95.5% identity (95.8% similar) in 400 aa overlap (1-394:1-393) 10 20 30 40 50 60 pF1KB4 MAQRYDELPHYGGMDGVGVPASMYGDPHAPRPIPPVHHLNHGPPLHATQHYGAHAPHPNV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 MAQRYDELPHYGGMDGVGVPASMYGDPHAPRPIPPVHHLNHGPPLHATQHYGAHAPHPNV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 MPASMGSAVNDALKRDKDAIYGHPLFPLLALVFEKCELATCTPREPGVAGGDVCSSDSFN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 MPASMGSAVNDALKRDKDAIYGHPLFPLLALVFEKCELATCTPREPGVAGGDVCSSDSFN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 EDIAVFAKQVRAEKPLFSSNPELDNLMIQAIQVLRFHLLELEKVHELCDNFCHRYISCLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 EDIAVFAKQVRAEKPLFSSNPELDNLMIQAIQVLRFHLLELEKVHELCDNFCHRYISCLK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 GKMPIDLVIDERDGSSKSDHEELSGSSTNLADHNPSSWRDHDDATSTHSAGTPGPSSGGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 GKMPIDLVIDERDGSSKSDHEELSGSSTNLADHNPSSWRDHDDATSTHSAGTPGPSSGGH 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 ASQSGDNSSEQGDGLDNSVASPGTGDDDDPDKDKKRQKKRGIFPKVATNIMRAWLFQHLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 ASQSGDNSSEQGDGLDNSVASPGTGDDDDPDKDKKRQKKRGIFPKVATNIMRAWLFQHLT 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 HPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRAGFLLDPSVSQGAAYS ::::::::::::::::::::::::::::::::::::::::::::: :::::::: CCDS10 HPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRA-------VSQGAAYS 310 320 330 340 350 370 380 390 400 pF1KB4 PEGQPMGSFVLDGQQHMGIRPAG--PMSG----MGMNMGMDGQWHYM ::::::::::::::::::::::: : : .: ::: CCDS10 PEGQPMGSFVLDGQQHMGIRPAGLQSMPGDYVSQGGPMGMSMAQPSYTPPQMTPHPTQLR 360 370 380 390 400 410 CCDS10 HGPPMHSYLPSHPHHPAMMMHGGPPTHPGMTMSAQSPTMLNSVDPNVGGQVMDIHAQ 420 430 440 450 460 470 >>CCDS45220.1 MEIS2 gene_id:4212|Hs108|chr15 (306 aa) initn: 1753 init1: 1753 opt: 2090 Z-score: 1746.5 bits: 331.6 E(32554): 5.9e-91 Smith-Waterman score: 2090; 97.4% identity (97.8% similar) in 313 aa overlap (89-401:1-306) 60 70 80 90 100 110 pF1KB4 NVMPASMGSAVNDALKRDKDAIYGHPLFPLLALVFEKCELATCTPREPGVAGGDVCSSDS .::::::::::::::::::::::::::::: CCDS45 MALVFEKCELATCTPREPGVAGGDVCSSDS 10 20 30 120 130 140 150 160 170 pF1KB4 FNEDIAVFAKQVRAEKPLFSSNPELDNLMIQAIQVLRFHLLELEKVHELCDNFCHRYISC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 FNEDIAVFAKQVRAEKPLFSSNPELDNLMIQAIQVLRFHLLELEKVHELCDNFCHRYISC 40 50 60 70 80 90 180 190 200 210 220 230 pF1KB4 LKGKMPIDLVIDERDGSSKSDHEELSGSSTNLADHNPSSWRDHDDATSTHSAGTPGPSSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 LKGKMPIDLVIDERDGSSKSDHEELSGSSTNLADHNPSSWRDHDDATSTHSAGTPGPSSG 100 110 120 130 140 150 240 250 260 270 280 290 pF1KB4 GHASQSGDNSSEQGDGLDNSVASPGTGDDDDPDKDKKRQKKRGIFPKVATNIMRAWLFQH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 GHASQSGDNSSEQGDGLDNSVASPGTGDDDDPDKDKKRQKKRGIFPKVATNIMRAWLFQH 160 170 180 190 200 210 300 310 320 330 340 350 pF1KB4 LTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRAGFLLDPSVSQGAA ::::::::::::::::::::::::::::::::::::::::::::::: :::::: CCDS45 LTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRA-------VSQGAA 220 230 240 250 260 360 370 380 390 400 pF1KB4 YSPEGQPMGSFVLDGQQHMGIRPAGPMSGMGMNMGMDGQWHYM ::::::::::::::::::::::::::::::::::::::::::: CCDS45 YSPEGQPMGSFVLDGQQHMGIRPAGPMSGMGMNMGMDGQWHYM 270 280 290 300 >>CCDS46309.1 MEIS1 gene_id:4211|Hs108|chr2 (390 aa) initn: 1548 init1: 947 opt: 2074 Z-score: 1731.8 bits: 329.3 E(32554): 3.8e-90 Smith-Waterman score: 2353; 84.3% identity (93.3% similar) in 401 aa overlap (1-401:1-390) 10 20 30 40 50 60 pF1KB4 MAQRYDELPHYGGMDGVGVPASMYGDPHAPRPIPPVHHLNHGPPLHATQHYGAHAPHPNV ::::::.:::::::::::.:..::::::: : . ::::::::::::. :. :. : :. CCDS46 MAQRYDDLPHYGGMDGVGIPSTMYGDPHAARSMQPVHHLNHGPPLHSHQY--PHTAHTNA 10 20 30 40 50 70 80 90 100 110 120 pF1KB4 MPASMGSAVNDALKRDKDAIYGHPLFPLLALVFEKCELATCTPREPGVAGGDVCSSDSFN : ::::.:::::::::::::::::::::::.::::::::::::::::::::::::.::: CCDS46 MAPSMGSSVNDALKRDKDAIYGHPLFPLLALIFEKCELATCTPREPGVAGGDVCSSESFN 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB4 EDIAVFAKQVRAEKPLFSSNPELDNLMIQAIQVLRFHLLELEKVHELCDNFCHRYISCLK :::::::::.:::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 EDIAVFAKQIRAEKPLFSSNPELDNLMIQAIQVLRFHLLELEKVHELCDNFCHRYISCLK 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB4 GKMPIDLVIDERDGSSKSDHEELSGSSTNLADHNPSSWRDHDDATSTHSAGTPGPSSGGH ::::::::::.:.:.:::: :... :.::.:. :: :::::..::.:.:::::::::: CCDS46 GKMPIDLVIDDREGGSKSDSEDIT-RSANLTDQ-PSWNRDHDDTASTRSGGTPGPSSGGH 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB4 ASQSGDNSSEQGDGLDNSVASPGTGDDDDPDKDKKRQKKRGIFPKVATNIMRAWLFQHLT .:.:::::::::::::::::::.:::::::::::::.::::::::::::::::::::::: CCDS46 TSHSGDNSSEQGDGLDNSVASPSTGDDDDPDKDKKRHKKRGIFPKVATNIMRAWLFQHLT 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB4 HPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRAGFLLDPSVSQGAAYS ::::::::::::::::::::::::::::::::::::::::::::: ::::. :. CCDS46 HPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRA-------VSQGTPYN 300 310 320 330 340 370 380 390 400 pF1KB4 PEGQPMGSFVLDGQQHMGIRPAGPMSGMGMNMGMDGQWHYM :.:::::.::.::::::::: ::::::::::::.:::::: CCDS46 PDGQPMGGFVMDGQQHMGIRAPGPMSGMGMNMGMEGQWHYM 350 360 370 380 390 >>CCDS74406.1 MEIS3 gene_id:56917|Hs108|chr19 (375 aa) initn: 1795 init1: 1125 opt: 1599 Z-score: 1338.4 bits: 256.4 E(32554): 3.1e-68 Smith-Waterman score: 1755; 66.3% identity (82.0% similar) in 410 aa overlap (1-401:1-375) 10 20 30 40 50 pF1KB4 MAQRYDELPHYGGM-DGVGVPASMYGDPHAPRPIPPVHHLNHGPPLHATQHYGAHAPHPN ::.:::::::: :. :: ::.. . :. .: : :: :: : : :. CCDS74 MARRYDELPHYPGIVDG---PAALAS---FPETVPAVP----GP-------YGPHRP-PQ 10 20 30 40 60 70 80 90 100 110 pF1KB4 VMPASMGSAVNDALKRDKDAIYGHPLFPLLALVFEKCELATCTPREPGVAG------GDV .: .. : :.:::.:: ::::::::::::::::::::::.::. . :: ::: CCDS74 PLPPGLDS---DGLKREKDEIYGHPLFPLLALVFEKCELATCSPRDGAGAGLGTPPGGDV 50 60 70 80 90 120 130 140 150 160 170 pF1KB4 CSSDSFNEDIAVFAKQVRAEKPLFSSNPELDNLMIQAIQVLRFHLLELEKVHELCDNFCH :::::::::::.::::::.:.:::::::::::::::::::::::::::::::.::::::: CCDS74 CSSDSFNEDIAAFAKQVRSERPLFSSNPELDNLMIQAIQVLRFHLLELEKVHDLCDNFCH 100 110 120 130 140 150 180 190 200 210 220 230 pF1KB4 RYISCLKGKMPIDLVIDERDGSSKSDHEELSGSSTNLADHNPSSW-RDHDDATSTHSAGT :::.::::::::::::..:::. . : :. .: .: :.: . : :::.:. :.: :: CCDS74 RYITCLKGKMPIDLVIEDRDGGCREDFEDYPASCPSLPDQN-NMWIRDHEDSGSVH-LGT 160 170 180 190 200 210 240 250 260 270 280 290 pF1KB4 PGPSSGGHASQSGDNSSEQGDGLDNSVASPGTG-DDDDPDKDKKRQKKRGIFPKVATNIM ::::::: :::::::::.::::::.:::::..: .:.: :....:.:::::::::::::: CCDS74 PGPSSGGLASQSGDNSSDQGDGLDTSVASPSSGGEDEDLDQERRRNKKRGIFPKVATNIM 220 230 240 250 260 270 300 310 320 330 340 350 pF1KB4 RAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRAGFLLDP ::::::::.::::::::::::::::::::::::::::::::::::::::::::.: CCDS74 RAWLFQHLSHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRTG----- 280 290 300 310 320 330 360 370 380 390 400 pF1KB4 SVSQGAAYSPEGQPMGSFVLDGQQHMGIRPAGPMSGMGMNMGMDGQWHYM ::::.::::::.:... . : :...:: : ..::.....:.:::. CCDS74 ---QGAAFSPEGQPIGGYT-ETQPHVAVRPPG---SVGMSLNLEGEWHYL 340 350 360 370 >>CCDS33064.1 MEIS3 gene_id:56917|Hs108|chr19 (421 aa) initn: 1781 init1: 818 opt: 1229 Z-score: 1031.2 bits: 199.7 E(32554): 4.1e-51 Smith-Waterman score: 1642; 59.7% identity (73.6% similar) in 454 aa overlap (1-399:1-419) 10 20 30 40 50 pF1KB4 MAQRYDELPHYGGM-DGVGVPASMYGDPHAPRPIPPVHHLNHGPPLHATQHYGAHAPHPN ::.:::::::: :. :: ::.. . :. .: : :: :: : : :. CCDS33 MARRYDELPHYPGIVDG---PAALAS---FPETVPAVP----GP-------YGPHRP-PQ 10 20 30 40 60 70 80 90 100 110 pF1KB4 VMPASMGSAVNDALKRDKDAIYGHPLFPLLALVFEKCELATCTPREPGVAG------GDV .: .. : :.:::.:: ::::::::::::::::::::::.::. . :: ::: CCDS33 PLPPGLDS---DGLKREKDEIYGHPLFPLLALVFEKCELATCSPRDGAGAGLGTPPGGDV 50 60 70 80 90 120 130 140 150 160 170 pF1KB4 CSSDSFNEDIAVFAKQVRAEKPLFSSNPELDNLMIQAIQVLRFHLLELEKVHELCDNFCH :::::::::::.::::::.:.:::::::::::::::::::::::::::::::.::::::: CCDS33 CSSDSFNEDIAAFAKQVRSERPLFSSNPELDNLMIQAIQVLRFHLLELEKVHDLCDNFCH 100 110 120 130 140 150 180 190 200 210 220 230 pF1KB4 RYISCLKGKMPIDLVIDERDGSSKSDHEELSGSSTNLADHNPSSW-RDHDDATSTHSAGT :::.::::::::::::..:::. . : :. .: .: :.: . : :::.:. :.: :: CCDS33 RYITCLKGKMPIDLVIEDRDGGCREDFEDYPASCPSLPDQN-NMWIRDHEDSGSVH-LGT 160 170 180 190 200 210 240 250 260 270 280 290 pF1KB4 PGPSSGGHASQSGDNSSEQGDGLDNSVASPGTG-DDDDPDKDKKRQKKRGIFPKVATNIM ::::::: :::::::::.::::::.:::::..: .:.: :....:.:::::::::::::: CCDS33 PGPSSGGLASQSGDNSSDQGDGLDTSVASPSSGGEDEDLDQERRRNKKRGIFPKVATNIM 220 230 240 250 260 270 300 pF1KB4 RAWLFQHLT----------------------------------------------HPYPS ::::::::. ::::: CCDS33 RAWLFQHLSRRSEAPVLPDVCLGLGSPSPGPRWARPWGSDCGRPGRQSDSCWWLQHPYPS 280 290 300 310 320 330 310 320 330 340 350 360 pF1KB4 EEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRAGFLLDPSVSQGAAYSPEGQP :::::::::::::::::::::::::::::::::::::::.: ::::.:::::: CCDS33 EEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRTG--------QGAAFSPEGQP 340 350 360 370 380 370 380 390 400 pF1KB4 MGSFVLDGQQHMGIRPAGPMSGMGMNMGMDGQWHYM .:... . : :...:: : ..::.....:.:: CCDS33 IGGYT-ETQPHVAVRPPG---SVGMSLNLEGEWHYL 390 400 410 420 401 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 15:19:14 2016 done: Thu Nov 3 15:19:15 2016 Total Scan time: 3.280 Total Display time: 0.040 Function used was FASTA [36.3.4 Apr, 2011]