Result of FASTA (omim) for
pF1KB4674
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB4674, 392 aa
1>>>pF1KB4674 392 - 392 aa - 392 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.3242+/-0.00036; mu= 16.3882+/- 0.022
mean_var=64.5608+/-13.019, 0's: 0 Z-trim(112.7): 13 B-trim: 0 in 0/54
Lambda= 0.159621
statistics sampled from 21769 (21781) to 21769 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.633), E-opt: 0.2 (0.255), width: 16
Scan time: 8.210
The best scores are: opt bits E(85289)
NP_000047 (OMIM: 248600,248611) 2-oxoisovalerate d ( 392) 2677 625.4 7.1e-179
NP_898871 (OMIM: 248600,248611) 2-oxoisovalerate d ( 392) 2677 625.4 7.1e-179
XP_011534326 (OMIM: 248600,248611) PREDICTED: 2-ox ( 353) 2332 545.9 5.4e-155
XP_011534327 (OMIM: 248600,248611) PREDICTED: 2-ox ( 350) 2330 545.5 7.3e-155
XP_011534325 (OMIM: 248600,248611) PREDICTED: 2-ox ( 359) 2330 545.5 7.5e-155
XP_005248813 (OMIM: 248600,248611) PREDICTED: 2-ox ( 360) 2330 545.5 7.5e-155
NP_001305904 (OMIM: 248600,248611) 2-oxoisovalerat ( 322) 2195 514.4 1.6e-145
XP_011534328 (OMIM: 248600,248611) PREDICTED: 2-ox ( 322) 2195 514.4 1.6e-145
NP_001302465 (OMIM: 179060,614111) pyruvate dehydr ( 341) 630 154.0 5e-37
NP_000916 (OMIM: 179060,614111) pyruvate dehydroge ( 359) 630 154.0 5.3e-37
NP_001166939 (OMIM: 179060,614111) pyruvate dehydr ( 341) 235 63.0 1.2e-09
>>NP_000047 (OMIM: 248600,248611) 2-oxoisovalerate dehyd (392 aa)
initn: 2677 init1: 2677 opt: 2677 Z-score: 3332.4 bits: 625.4 E(85289): 7.1e-179
Smith-Waterman score: 2677; 100.0% identity (100.0% similar) in 392 aa overlap (1-392:1-392)
10 20 30 40 50 60
pF1KB4 MAVVAAAAGWLLRLRAAGAEGHWRRLPGAGLARGFLHPAATVEDAAQRRQVAHFTFQPDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MAVVAAAAGWLLRLRAAGAEGHWRRLPGAGLARGFLHPAATVEDAAQRRQVAHFTFQPDP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 EPREYGQTQKMNLFQSVTSALDNSLAKDPTAVIFGEDVAFGGVFRCTVGLRDKYGKDRVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 EPREYGQTQKMNLFQSVTSALDNSLAKDPTAVIFGEDVAFGGVFRCTVGLRDKYGKDRVF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 NTPLCEQGIVGFGIGIAVTGATAIAEIQFADYIFPAFDQIVNEAAKYRYRSGDLFNCGSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 NTPLCEQGIVGFGIGIAVTGATAIAEIQFADYIFPAFDQIVNEAAKYRYRSGDLFNCGSL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 TIRSPWGCVGHGALYHSQSPEAFFAHCPGIKVVIPRSPFQAKGLLLSCIEDKNPCIFFEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TIRSPWGCVGHGALYHSQSPEAFFAHCPGIKVVIPRSPFQAKGLLLSCIEDKNPCIFFEP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 KILYRAAAEEVPIEPYNIPLSQAEVIQEGSDVTLVAWGTQVHVIREVASMAKEKLGVSCE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 KILYRAAAEEVPIEPYNIPLSQAEVIQEGSDVTLVAWGTQVHVIREVASMAKEKLGVSCE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 VIDLRTIIPWDVDTICKSVIKTGRLLISHEAPLTGGFASEISSTVQEECFLNLEAPISRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VIDLRTIIPWDVDTICKSVIKTGRLLISHEAPLTGGFASEISSTVQEECFLNLEAPISRV
310 320 330 340 350 360
370 380 390
pF1KB4 CGYDTPFPHIFEPFYIPDKWKCYDALRKMINY
::::::::::::::::::::::::::::::::
NP_000 CGYDTPFPHIFEPFYIPDKWKCYDALRKMINY
370 380 390
>>NP_898871 (OMIM: 248600,248611) 2-oxoisovalerate dehyd (392 aa)
initn: 2677 init1: 2677 opt: 2677 Z-score: 3332.4 bits: 625.4 E(85289): 7.1e-179
Smith-Waterman score: 2677; 100.0% identity (100.0% similar) in 392 aa overlap (1-392:1-392)
10 20 30 40 50 60
pF1KB4 MAVVAAAAGWLLRLRAAGAEGHWRRLPGAGLARGFLHPAATVEDAAQRRQVAHFTFQPDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_898 MAVVAAAAGWLLRLRAAGAEGHWRRLPGAGLARGFLHPAATVEDAAQRRQVAHFTFQPDP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 EPREYGQTQKMNLFQSVTSALDNSLAKDPTAVIFGEDVAFGGVFRCTVGLRDKYGKDRVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_898 EPREYGQTQKMNLFQSVTSALDNSLAKDPTAVIFGEDVAFGGVFRCTVGLRDKYGKDRVF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 NTPLCEQGIVGFGIGIAVTGATAIAEIQFADYIFPAFDQIVNEAAKYRYRSGDLFNCGSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_898 NTPLCEQGIVGFGIGIAVTGATAIAEIQFADYIFPAFDQIVNEAAKYRYRSGDLFNCGSL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 TIRSPWGCVGHGALYHSQSPEAFFAHCPGIKVVIPRSPFQAKGLLLSCIEDKNPCIFFEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_898 TIRSPWGCVGHGALYHSQSPEAFFAHCPGIKVVIPRSPFQAKGLLLSCIEDKNPCIFFEP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 KILYRAAAEEVPIEPYNIPLSQAEVIQEGSDVTLVAWGTQVHVIREVASMAKEKLGVSCE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_898 KILYRAAAEEVPIEPYNIPLSQAEVIQEGSDVTLVAWGTQVHVIREVASMAKEKLGVSCE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 VIDLRTIIPWDVDTICKSVIKTGRLLISHEAPLTGGFASEISSTVQEECFLNLEAPISRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_898 VIDLRTIIPWDVDTICKSVIKTGRLLISHEAPLTGGFASEISSTVQEECFLNLEAPISRV
310 320 330 340 350 360
370 380 390
pF1KB4 CGYDTPFPHIFEPFYIPDKWKCYDALRKMINY
::::::::::::::::::::::::::::::::
NP_898 CGYDTPFPHIFEPFYIPDKWKCYDALRKMINY
370 380 390
>>XP_011534326 (OMIM: 248600,248611) PREDICTED: 2-oxoiso (353 aa)
initn: 2332 init1: 2332 opt: 2332 Z-score: 2903.7 bits: 545.9 E(85289): 5.4e-155
Smith-Waterman score: 2332; 99.7% identity (100.0% similar) in 347 aa overlap (1-347:1-347)
10 20 30 40 50 60
pF1KB4 MAVVAAAAGWLLRLRAAGAEGHWRRLPGAGLARGFLHPAATVEDAAQRRQVAHFTFQPDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAVVAAAAGWLLRLRAAGAEGHWRRLPGAGLARGFLHPAATVEDAAQRRQVAHFTFQPDP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 EPREYGQTQKMNLFQSVTSALDNSLAKDPTAVIFGEDVAFGGVFRCTVGLRDKYGKDRVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EPREYGQTQKMNLFQSVTSALDNSLAKDPTAVIFGEDVAFGGVFRCTVGLRDKYGKDRVF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 NTPLCEQGIVGFGIGIAVTGATAIAEIQFADYIFPAFDQIVNEAAKYRYRSGDLFNCGSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NTPLCEQGIVGFGIGIAVTGATAIAEIQFADYIFPAFDQIVNEAAKYRYRSGDLFNCGSL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 TIRSPWGCVGHGALYHSQSPEAFFAHCPGIKVVIPRSPFQAKGLLLSCIEDKNPCIFFEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TIRSPWGCVGHGALYHSQSPEAFFAHCPGIKVVIPRSPFQAKGLLLSCIEDKNPCIFFEP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 KILYRAAAEEVPIEPYNIPLSQAEVIQEGSDVTLVAWGTQVHVIREVASMAKEKLGVSCE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KILYRAAAEEVPIEPYNIPLSQAEVIQEGSDVTLVAWGTQVHVIREVASMAKEKLGVSCE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 VIDLRTIIPWDVDTICKSVIKTGRLLISHEAPLTGGFASEISSTVQEECFLNLEAPISRV
::::::::::::::::::::::::::::::::::::::::::::::.
XP_011 VIDLRTIIPWDVDTICKSVIKTGRLLISHEAPLTGGFASEISSTVQQLEDTGD
310 320 330 340 350
370 380 390
pF1KB4 CGYDTPFPHIFEPFYIPDKWKCYDALRKMINY
>>XP_011534327 (OMIM: 248600,248611) PREDICTED: 2-oxoiso (350 aa)
initn: 2330 init1: 2330 opt: 2330 Z-score: 2901.3 bits: 545.5 E(85289): 7.3e-155
Smith-Waterman score: 2330; 100.0% identity (100.0% similar) in 346 aa overlap (1-346:1-346)
10 20 30 40 50 60
pF1KB4 MAVVAAAAGWLLRLRAAGAEGHWRRLPGAGLARGFLHPAATVEDAAQRRQVAHFTFQPDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAVVAAAAGWLLRLRAAGAEGHWRRLPGAGLARGFLHPAATVEDAAQRRQVAHFTFQPDP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 EPREYGQTQKMNLFQSVTSALDNSLAKDPTAVIFGEDVAFGGVFRCTVGLRDKYGKDRVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EPREYGQTQKMNLFQSVTSALDNSLAKDPTAVIFGEDVAFGGVFRCTVGLRDKYGKDRVF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 NTPLCEQGIVGFGIGIAVTGATAIAEIQFADYIFPAFDQIVNEAAKYRYRSGDLFNCGSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NTPLCEQGIVGFGIGIAVTGATAIAEIQFADYIFPAFDQIVNEAAKYRYRSGDLFNCGSL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 TIRSPWGCVGHGALYHSQSPEAFFAHCPGIKVVIPRSPFQAKGLLLSCIEDKNPCIFFEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TIRSPWGCVGHGALYHSQSPEAFFAHCPGIKVVIPRSPFQAKGLLLSCIEDKNPCIFFEP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 KILYRAAAEEVPIEPYNIPLSQAEVIQEGSDVTLVAWGTQVHVIREVASMAKEKLGVSCE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KILYRAAAEEVPIEPYNIPLSQAEVIQEGSDVTLVAWGTQVHVIREVASMAKEKLGVSCE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 VIDLRTIIPWDVDTICKSVIKTGRLLISHEAPLTGGFASEISSTVQEECFLNLEAPISRV
::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VIDLRTIIPWDVDTICKSVIKTGRLLISHEAPLTGGFASEISSTVQGLRF
310 320 330 340 350
370 380 390
pF1KB4 CGYDTPFPHIFEPFYIPDKWKCYDALRKMINY
>>XP_011534325 (OMIM: 248600,248611) PREDICTED: 2-oxoiso (359 aa)
initn: 2330 init1: 2330 opt: 2330 Z-score: 2901.1 bits: 545.5 E(85289): 7.5e-155
Smith-Waterman score: 2330; 100.0% identity (100.0% similar) in 346 aa overlap (1-346:1-346)
10 20 30 40 50 60
pF1KB4 MAVVAAAAGWLLRLRAAGAEGHWRRLPGAGLARGFLHPAATVEDAAQRRQVAHFTFQPDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAVVAAAAGWLLRLRAAGAEGHWRRLPGAGLARGFLHPAATVEDAAQRRQVAHFTFQPDP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 EPREYGQTQKMNLFQSVTSALDNSLAKDPTAVIFGEDVAFGGVFRCTVGLRDKYGKDRVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EPREYGQTQKMNLFQSVTSALDNSLAKDPTAVIFGEDVAFGGVFRCTVGLRDKYGKDRVF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 NTPLCEQGIVGFGIGIAVTGATAIAEIQFADYIFPAFDQIVNEAAKYRYRSGDLFNCGSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NTPLCEQGIVGFGIGIAVTGATAIAEIQFADYIFPAFDQIVNEAAKYRYRSGDLFNCGSL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 TIRSPWGCVGHGALYHSQSPEAFFAHCPGIKVVIPRSPFQAKGLLLSCIEDKNPCIFFEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TIRSPWGCVGHGALYHSQSPEAFFAHCPGIKVVIPRSPFQAKGLLLSCIEDKNPCIFFEP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 KILYRAAAEEVPIEPYNIPLSQAEVIQEGSDVTLVAWGTQVHVIREVASMAKEKLGVSCE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KILYRAAAEEVPIEPYNIPLSQAEVIQEGSDVTLVAWGTQVHVIREVASMAKEKLGVSCE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 VIDLRTIIPWDVDTICKSVIKTGRLLISHEAPLTGGFASEISSTVQEECFLNLEAPISRV
::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VIDLRTIIPWDVDTICKSVIKTGRLLISHEAPLTGGFASEISSTVQMSVIQSVCDLPIL
310 320 330 340 350
370 380 390
pF1KB4 CGYDTPFPHIFEPFYIPDKWKCYDALRKMINY
>>XP_005248813 (OMIM: 248600,248611) PREDICTED: 2-oxoiso (360 aa)
initn: 2330 init1: 2330 opt: 2330 Z-score: 2901.1 bits: 545.5 E(85289): 7.5e-155
Smith-Waterman score: 2330; 100.0% identity (100.0% similar) in 346 aa overlap (1-346:1-346)
10 20 30 40 50 60
pF1KB4 MAVVAAAAGWLLRLRAAGAEGHWRRLPGAGLARGFLHPAATVEDAAQRRQVAHFTFQPDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MAVVAAAAGWLLRLRAAGAEGHWRRLPGAGLARGFLHPAATVEDAAQRRQVAHFTFQPDP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 EPREYGQTQKMNLFQSVTSALDNSLAKDPTAVIFGEDVAFGGVFRCTVGLRDKYGKDRVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EPREYGQTQKMNLFQSVTSALDNSLAKDPTAVIFGEDVAFGGVFRCTVGLRDKYGKDRVF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 NTPLCEQGIVGFGIGIAVTGATAIAEIQFADYIFPAFDQIVNEAAKYRYRSGDLFNCGSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NTPLCEQGIVGFGIGIAVTGATAIAEIQFADYIFPAFDQIVNEAAKYRYRSGDLFNCGSL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 TIRSPWGCVGHGALYHSQSPEAFFAHCPGIKVVIPRSPFQAKGLLLSCIEDKNPCIFFEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TIRSPWGCVGHGALYHSQSPEAFFAHCPGIKVVIPRSPFQAKGLLLSCIEDKNPCIFFEP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 KILYRAAAEEVPIEPYNIPLSQAEVIQEGSDVTLVAWGTQVHVIREVASMAKEKLGVSCE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KILYRAAAEEVPIEPYNIPLSQAEVIQEGSDVTLVAWGTQVHVIREVASMAKEKLGVSCE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 VIDLRTIIPWDVDTICKSVIKTGRLLISHEAPLTGGFASEISSTVQEECFLNLEAPISRV
::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VIDLRTIIPWDVDTICKSVIKTGRLLISHEAPLTGGFASEISSTVQIYPHERTSVKFSVN
310 320 330 340 350 360
370 380 390
pF1KB4 CGYDTPFPHIFEPFYIPDKWKCYDALRKMINY
>>NP_001305904 (OMIM: 248600,248611) 2-oxoisovalerate de (322 aa)
initn: 2195 init1: 2195 opt: 2195 Z-score: 2733.8 bits: 514.4 E(85289): 1.6e-145
Smith-Waterman score: 2195; 100.0% identity (100.0% similar) in 322 aa overlap (71-392:1-322)
50 60 70 80 90 100
pF1KB4 TVEDAAQRRQVAHFTFQPDPEPREYGQTQKMNLFQSVTSALDNSLAKDPTAVIFGEDVAF
::::::::::::::::::::::::::::::
NP_001 MNLFQSVTSALDNSLAKDPTAVIFGEDVAF
10 20 30
110 120 130 140 150 160
pF1KB4 GGVFRCTVGLRDKYGKDRVFNTPLCEQGIVGFGIGIAVTGATAIAEIQFADYIFPAFDQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GGVFRCTVGLRDKYGKDRVFNTPLCEQGIVGFGIGIAVTGATAIAEIQFADYIFPAFDQI
40 50 60 70 80 90
170 180 190 200 210 220
pF1KB4 VNEAAKYRYRSGDLFNCGSLTIRSPWGCVGHGALYHSQSPEAFFAHCPGIKVVIPRSPFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VNEAAKYRYRSGDLFNCGSLTIRSPWGCVGHGALYHSQSPEAFFAHCPGIKVVIPRSPFQ
100 110 120 130 140 150
230 240 250 260 270 280
pF1KB4 AKGLLLSCIEDKNPCIFFEPKILYRAAAEEVPIEPYNIPLSQAEVIQEGSDVTLVAWGTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AKGLLLSCIEDKNPCIFFEPKILYRAAAEEVPIEPYNIPLSQAEVIQEGSDVTLVAWGTQ
160 170 180 190 200 210
290 300 310 320 330 340
pF1KB4 VHVIREVASMAKEKLGVSCEVIDLRTIIPWDVDTICKSVIKTGRLLISHEAPLTGGFASE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VHVIREVASMAKEKLGVSCEVIDLRTIIPWDVDTICKSVIKTGRLLISHEAPLTGGFASE
220 230 240 250 260 270
350 360 370 380 390
pF1KB4 ISSTVQEECFLNLEAPISRVCGYDTPFPHIFEPFYIPDKWKCYDALRKMINY
::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ISSTVQEECFLNLEAPISRVCGYDTPFPHIFEPFYIPDKWKCYDALRKMINY
280 290 300 310 320
>>XP_011534328 (OMIM: 248600,248611) PREDICTED: 2-oxoiso (322 aa)
initn: 2195 init1: 2195 opt: 2195 Z-score: 2733.8 bits: 514.4 E(85289): 1.6e-145
Smith-Waterman score: 2195; 100.0% identity (100.0% similar) in 322 aa overlap (71-392:1-322)
50 60 70 80 90 100
pF1KB4 TVEDAAQRRQVAHFTFQPDPEPREYGQTQKMNLFQSVTSALDNSLAKDPTAVIFGEDVAF
::::::::::::::::::::::::::::::
XP_011 MNLFQSVTSALDNSLAKDPTAVIFGEDVAF
10 20 30
110 120 130 140 150 160
pF1KB4 GGVFRCTVGLRDKYGKDRVFNTPLCEQGIVGFGIGIAVTGATAIAEIQFADYIFPAFDQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GGVFRCTVGLRDKYGKDRVFNTPLCEQGIVGFGIGIAVTGATAIAEIQFADYIFPAFDQI
40 50 60 70 80 90
170 180 190 200 210 220
pF1KB4 VNEAAKYRYRSGDLFNCGSLTIRSPWGCVGHGALYHSQSPEAFFAHCPGIKVVIPRSPFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VNEAAKYRYRSGDLFNCGSLTIRSPWGCVGHGALYHSQSPEAFFAHCPGIKVVIPRSPFQ
100 110 120 130 140 150
230 240 250 260 270 280
pF1KB4 AKGLLLSCIEDKNPCIFFEPKILYRAAAEEVPIEPYNIPLSQAEVIQEGSDVTLVAWGTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AKGLLLSCIEDKNPCIFFEPKILYRAAAEEVPIEPYNIPLSQAEVIQEGSDVTLVAWGTQ
160 170 180 190 200 210
290 300 310 320 330 340
pF1KB4 VHVIREVASMAKEKLGVSCEVIDLRTIIPWDVDTICKSVIKTGRLLISHEAPLTGGFASE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VHVIREVASMAKEKLGVSCEVIDLRTIIPWDVDTICKSVIKTGRLLISHEAPLTGGFASE
220 230 240 250 260 270
350 360 370 380 390
pF1KB4 ISSTVQEECFLNLEAPISRVCGYDTPFPHIFEPFYIPDKWKCYDALRKMINY
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ISSTVQEECFLNLEAPISRVCGYDTPFPHIFEPFYIPDKWKCYDALRKMINY
280 290 300 310 320
>>NP_001302465 (OMIM: 179060,614111) pyruvate dehydrogen (341 aa)
initn: 464 init1: 178 opt: 630 Z-score: 785.7 bits: 154.0 E(85289): 5e-37
Smith-Waterman score: 630; 34.4% identity (67.1% similar) in 331 aa overlap (69-391:13-340)
40 50 60 70 80 90
pF1KB4 AATVEDAAQRRQVAHFTFQPDPEPREYGQTQKMNLFQSVTSALDNSLAKDPTAVIFGEDV
..... .......:. : .: . ..::.:
NP_001 MAAVSGLVRRPLREVTVRDAINQGMDEELERDEKVFLLGEEV
10 20 30 40
100 110 120 130 140 150
pF1KB4 A-FGGVFRCTVGLRDKYGKDRVFNTPLCEQGIVGFGIGIAVTGATAIAEIQFADYIFPAF
: . :... . :: ::: :...::. :.:..:...: :..: : :.. .. . :.
NP_001 AQYDGAYKVSRGLWKKYGDKRIIDTPISEMGFAGIAVGAAMAGLRPICEFMTFNFSMQAI
50 60 70 80 90 100
160 170 180 190 200 210
pF1KB4 DQIVNEAAKYRYRSGDLFNCGSLTIRSPWGCVGHGALYHSQSPEAFFAHCPGIKVVIPRS
::..: ::: : :: : ...:.: : . : ::: :...::::.::: : .
NP_001 DQVINSAAKTYYMSGGLQPV-PIVFRGPNGASAGVAAQHSQCFAAWYGHCPGLKVVSPWN
110 120 130 140 150 160
220 230 240 250 260 270
pF1KB4 PFQAKGLLLSCIEDKNPCIFFEPKILYRAAAE---EVPIEPYNIPLSQAEVIQEGSDVTL
.::::. : :.:.:: . .: ...: . : :. . . ::...:.. ..:. .:.
NP_001 SEDAKGLIKSAIRDNNPVVVLENELMYGVPFEFPPEAQSKDFLIPIGKAKIERQGTHITV
170 180 190 200 210 220
280 290 300 310 320 330
pF1KB4 VAWGTQV-HVIREVASMAKEKLGVSCEVIDLRTIIPWDVDTICKSVIKTGRLLISHEAPL
:. . : : .. .: ..:: :: ::::..::: : :..:: ::.::..:. . .
NP_001 VSHSRPVGHCLEAAAVLSKE--GVECEVINMRTIRPMDMETIEASVMKTNHLVTVEGGWP
230 240 250 260 270
340 350 360 370 380 390
pF1KB4 TGGFASEISSTVQEECFLN-LEAPISRVCGYDTPFPH--IFEPFYIPDKWKCYDALRKMI
: ..:: . ..: .: :.:: :: : :.:.:. :.: ::. :..: .
NP_001 QFGVGAEICARIMEGPAFNFLDAPAVRVTGADVPMPYAKILEDNSIPQVKDIIFAIKKTL
280 290 300 310 320 330
pF1KB4 NY
:
NP_001 NI
340
>>NP_000916 (OMIM: 179060,614111) pyruvate dehydrogenase (359 aa)
initn: 464 init1: 178 opt: 630 Z-score: 785.3 bits: 154.0 E(85289): 5.3e-37
Smith-Waterman score: 630; 34.5% identity (67.0% similar) in 330 aa overlap (70-391:32-358)
40 50 60 70 80 90
pF1KB4 ATVEDAAQRRQVAHFTFQPDPEPREYGQTQKMNLFQSVTSALDNSLAKDPTAVIFGEDVA
.... .......:. : .: . ..::.::
NP_000 AAVSGLVRRPLREVSGLLKRRFHWTAPAALQVTVRDAINQGMDEELERDEKVFLLGEEVA
10 20 30 40 50 60
100 110 120 130 140 150
pF1KB4 -FGGVFRCTVGLRDKYGKDRVFNTPLCEQGIVGFGIGIAVTGATAIAEIQFADYIFPAFD
. :... . :: ::: :...::. :.:..:...: :..: : :.. .. . :.:
NP_000 QYDGAYKVSRGLWKKYGDKRIIDTPISEMGFAGIAVGAAMAGLRPICEFMTFNFSMQAID
70 80 90 100 110 120
160 170 180 190 200 210
pF1KB4 QIVNEAAKYRYRSGDLFNCGSLTIRSPWGCVGHGALYHSQSPEAFFAHCPGIKVVIPRSP
:..: ::: : :: : ...:.: : . : ::: :...::::.::: : .
NP_000 QVINSAAKTYYMSGGLQPV-PIVFRGPNGASAGVAAQHSQCFAAWYGHCPGLKVVSPWNS
130 140 150 160 170 180
220 230 240 250 260 270
pF1KB4 FQAKGLLLSCIEDKNPCIFFEPKILYRAAAE---EVPIEPYNIPLSQAEVIQEGSDVTLV
.::::. : :.:.:: . .: ...: . : :. . . ::...:.. ..:. .:.:
NP_000 EDAKGLIKSAIRDNNPVVVLENELMYGVPFEFPPEAQSKDFLIPIGKAKIERQGTHITVV
190 200 210 220 230 240
280 290 300 310 320 330
pF1KB4 AWGTQV-HVIREVASMAKEKLGVSCEVIDLRTIIPWDVDTICKSVIKTGRLLISHEAPLT
. . : : .. .: ..:: :: ::::..::: : :..:: ::.::..:. . .
NP_000 SHSRPVGHCLEAAAVLSKE--GVECEVINMRTIRPMDMETIEASVMKTNHLVTVEGGWPQ
250 260 270 280 290
340 350 360 370 380 390
pF1KB4 GGFASEISSTVQEECFLN-LEAPISRVCGYDTPFPH--IFEPFYIPDKWKCYDALRKMIN
: ..:: . ..: .: :.:: :: : :.:.:. :.: ::. :..: .:
NP_000 FGVGAEICARIMEGPAFNFLDAPAVRVTGADVPMPYAKILEDNSIPQVKDIIFAIKKTLN
300 310 320 330 340 350
pF1KB4 Y
NP_000 I
392 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 05:59:15 2016 done: Sat Nov 5 05:59:17 2016
Total Scan time: 8.210 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]