FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB4675, 494 aa 1>>>pF1KB4675 494 - 494 aa - 494 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.4888+/-0.000412; mu= 18.0125+/- 0.026 mean_var=97.6259+/-19.137, 0's: 0 Z-trim(112.1): 190 B-trim: 213 in 1/61 Lambda= 0.129805 statistics sampled from 20695 (20905) to 20695 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.622), E-opt: 0.2 (0.245), width: 16 Scan time: 8.360 The best scores are: opt bits E(85289) NP_005142 (OMIM: 607274) ubiquitin carboxyl-termin ( 494) 3245 618.7 1.2e-176 NP_001032411 (OMIM: 607274) ubiquitin carboxyl-ter ( 459) 2589 495.8 1.1e-139 XP_005272731 (OMIM: 300050) PREDICTED: ubiquitin c ( 690) 189 46.5 0.00028 XP_011542290 (OMIM: 300050) PREDICTED: ubiquitin c ( 690) 189 46.5 0.00028 XP_016864046 (OMIM: 612849) PREDICTED: ubiquitin c ( 341) 185 45.5 0.00029 NP_001127695 (OMIM: 612849) ubiquitin carboxyl-ter ( 359) 185 45.5 0.0003 NP_073743 (OMIM: 612849) ubiquitin carboxyl-termin ( 366) 185 45.5 0.0003 NP_004642 (OMIM: 300050) ubiquitin carboxyl-termin ( 963) 190 46.9 0.00032 XP_006719781 (OMIM: 604731) PREDICTED: ubiquitin c ( 775) 185 45.8 0.00052 XP_016875774 (OMIM: 604731) PREDICTED: ubiquitin c ( 860) 185 45.9 0.00056 XP_016875773 (OMIM: 604731) PREDICTED: ubiquitin c ( 860) 185 45.9 0.00056 NP_006304 (OMIM: 604731) ubiquitin carboxyl-termin ( 952) 185 45.9 0.0006 NP_001239007 (OMIM: 604731) ubiquitin carboxyl-ter ( 981) 185 45.9 0.00061 NP_955475 (OMIM: 603486) ubiquitin carboxyl-termin ( 916) 180 45.0 0.0011 NP_003354 (OMIM: 603486) ubiquitin carboxyl-termin ( 963) 180 45.0 0.0012 XP_011539358 (OMIM: 615146) PREDICTED: ubiquitin c ( 600) 163 41.6 0.0075 XP_006721395 (OMIM: 609818) PREDICTED: ubiquitin c ( 602) 163 41.6 0.0075 XP_016879352 (OMIM: 609818) PREDICTED: ubiquitin c ( 602) 163 41.6 0.0075 XP_011521745 (OMIM: 609818) PREDICTED: ubiquitin c ( 602) 163 41.6 0.0075 XP_011521743 (OMIM: 609818) PREDICTED: ubiquitin c ( 602) 163 41.6 0.0075 XP_016879358 (OMIM: 609818) PREDICTED: ubiquitin c ( 602) 163 41.6 0.0075 XP_011521742 (OMIM: 609818) PREDICTED: ubiquitin c ( 602) 163 41.6 0.0075 XP_016879354 (OMIM: 609818) PREDICTED: ubiquitin c ( 602) 163 41.6 0.0075 XP_016879356 (OMIM: 609818) PREDICTED: ubiquitin c ( 602) 163 41.6 0.0075 XP_016879355 (OMIM: 609818) PREDICTED: ubiquitin c ( 602) 163 41.6 0.0075 XP_016879357 (OMIM: 609818) PREDICTED: ubiquitin c ( 602) 163 41.6 0.0075 XP_016879353 (OMIM: 609818) PREDICTED: ubiquitin c ( 602) 163 41.6 0.0075 XP_016856218 (OMIM: 615146) PREDICTED: ubiquitin c ( 752) 163 41.7 0.0088 XP_011522361 (OMIM: 604334) PREDICTED: ubiquitin c ( 786) 163 41.7 0.0091 NP_005144 (OMIM: 609818) ubiquitin carboxyl-termin ( 798) 163 41.7 0.0092 NP_001259004 (OMIM: 609818) ubiquitin carboxyl-ter ( 802) 163 41.7 0.0092 XP_016856215 (OMIM: 615146) PREDICTED: ubiquitin c ( 804) 163 41.7 0.0092 XP_016856213 (OMIM: 615146) PREDICTED: ubiquitin c ( 812) 163 41.7 0.0093 XP_016856214 (OMIM: 615146) PREDICTED: ubiquitin c ( 812) 163 41.7 0.0093 XP_016856212 (OMIM: 615146) PREDICTED: ubiquitin c ( 820) 163 41.7 0.0094 NP_963920 (OMIM: 615146) ubiquitin carboxyl-termin ( 828) 163 41.7 0.0094 XP_011539357 (OMIM: 615146) PREDICTED: ubiquitin c ( 843) 163 41.8 0.0096 XP_005270706 (OMIM: 615146) PREDICTED: ubiquitin c ( 851) 163 41.8 0.0096 >>NP_005142 (OMIM: 607274) ubiquitin carboxyl-terminal h (494 aa) initn: 3245 init1: 3245 opt: 3245 Z-score: 3292.5 bits: 618.7 E(85289): 1.2e-176 Smith-Waterman score: 3245; 100.0% identity (100.0% similar) in 494 aa overlap (1-494:1-494) 10 20 30 40 50 60 pF1KB4 MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 IKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 IKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 QCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 QCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLH 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 MAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 MAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 SLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 SLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 QSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 QSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB4 PELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 PELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB4 QAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 QAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLY 430 440 450 460 470 480 490 pF1KB4 GPRRVEIMEEESEQ :::::::::::::: NP_005 GPRRVEIMEEESEQ 490 >>NP_001032411 (OMIM: 607274) ubiquitin carboxyl-termina (459 aa) initn: 3015 init1: 2589 opt: 2589 Z-score: 2629.0 bits: 495.8 E(85289): 1.1e-139 Smith-Waterman score: 2949; 92.9% identity (92.9% similar) in 494 aa overlap (1-494:1-459) 10 20 30 40 50 60 pF1KB4 MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 IKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATV ::::: :::::::::::::::::::: NP_001 IKIKN-----------------------------------MELPCGLTNLGNTCYMNATV 70 80 130 140 150 160 170 180 pF1KB4 QCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLH 90 100 110 120 130 140 190 200 210 220 230 240 pF1KB4 MAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKK 150 160 170 180 190 200 250 260 270 280 290 300 pF1KB4 SLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITK 210 220 230 240 250 260 310 320 330 340 350 360 pF1KB4 QSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCT 270 280 290 300 310 320 370 380 390 400 410 420 pF1KB4 PELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDL 330 340 350 360 370 380 430 440 450 460 470 480 pF1KB4 QAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLY 390 400 410 420 430 440 490 pF1KB4 GPRRVEIMEEESEQ :::::::::::::: NP_001 GPRRVEIMEEESEQ 450 >>XP_005272731 (OMIM: 300050) PREDICTED: ubiquitin carbo (690 aa) initn: 259 init1: 141 opt: 189 Z-score: 197.7 bits: 46.5 E(85289): 0.00028 Smith-Waterman score: 189; 27.7% identity (55.0% similar) in 202 aa overlap (82-266:11-204) 60 70 80 90 100 pF1KB4 TLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKT-VFVEDMTEEQLA-SAMELPCGLTN :::. :. ..:.::. ... ::::: XP_005 METRKKDGTWPSAQLHVMNNNMSEEDEDFKGQPGICGLTN 10 20 30 40 110 120 130 140 150 160 pF1KB4 LGNTCYMNATVQCIRSVPELKDALKR--YAGALRASGEMASAQYITAALRDLFDSM--DK :::::.::...::. .::.: . . : : . .. :. : :: . . XP_005 LGNTCFMNSALQCLSNVPQLTEYFLNNCYLEELNFRNPLGMKGEIAEAYADLVKQAWSGH 50 60 70 80 90 100 170 180 190 200 210 220 pF1KB4 TSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIED----- : .: .. . :.: :: : : :.:..: .. :.. :. .. XP_005 HRSIVPHVFKNKVGHFA-SQFL--G----YQQHDSQELLSFLLDGLHEDLNRVKKKEYVE 110 120 130 140 150 230 240 250 260 270 pF1KB4 --DSVKETDSSSASAATPSKKKS----LIDQFFGVEFETTMKCTESEEEEVTKGKENQLQ :.. . :. :. : ..:. ..: : :. :..:. : . . :: XP_005 LCDAAGRPDQEVAQEAWQNHKRRNDSVIVDTFHGL-FKSTLVCPDCGNVSVTFDPFCYLS 160 170 180 190 200 210 280 290 300 310 320 330 pF1KB4 LSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYK XP_005 VPLPISHKRVLEVFFIPMDPRRKPEQHRLVVPKKGKISDLCVALSKHTGISPERMMVADV 220 230 240 250 260 270 >>XP_011542290 (OMIM: 300050) PREDICTED: ubiquitin carbo (690 aa) initn: 259 init1: 141 opt: 189 Z-score: 197.7 bits: 46.5 E(85289): 0.00028 Smith-Waterman score: 189; 27.7% identity (55.0% similar) in 202 aa overlap (82-266:11-204) 60 70 80 90 100 pF1KB4 TLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKT-VFVEDMTEEQLA-SAMELPCGLTN :::. :. ..:.::. ... ::::: XP_011 METRKKDGTWPSAQLHVMNNNMSEEDEDFKGQPGICGLTN 10 20 30 40 110 120 130 140 150 160 pF1KB4 LGNTCYMNATVQCIRSVPELKDALKR--YAGALRASGEMASAQYITAALRDLFDSM--DK :::::.::...::. .::.: . . : : . .. :. : :: . . XP_011 LGNTCFMNSALQCLSNVPQLTEYFLNNCYLEELNFRNPLGMKGEIAEAYADLVKQAWSGH 50 60 70 80 90 100 170 180 190 200 210 220 pF1KB4 TSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIED----- : .: .. . :.: :: : : :.:..: .. :.. :. .. XP_011 HRSIVPHVFKNKVGHFA-SQFL--G----YQQHDSQELLSFLLDGLHEDLNRVKKKEYVE 110 120 130 140 150 230 240 250 260 270 pF1KB4 --DSVKETDSSSASAATPSKKKS----LIDQFFGVEFETTMKCTESEEEEVTKGKENQLQ :.. . :. :. : ..:. ..: : :. :..:. : . . :: XP_011 LCDAAGRPDQEVAQEAWQNHKRRNDSVIVDTFHGL-FKSTLVCPDCGNVSVTFDPFCYLS 160 170 180 190 200 210 280 290 300 310 320 330 pF1KB4 LSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYK XP_011 VPLPISHKRVLEVFFIPMDPRRKPEQHRLVVPKKGKISDLCVALSKHTGISPERMMVADV 220 230 240 250 260 270 >>XP_016864046 (OMIM: 612849) PREDICTED: ubiquitin carbo (341 aa) initn: 237 init1: 83 opt: 185 Z-score: 197.6 bits: 45.5 E(85289): 0.00029 Smith-Waterman score: 201; 22.1% identity (47.4% similar) in 380 aa overlap (90-457:21-334) 60 70 80 90 100 110 pF1KB4 NIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNAT .:. ::. : ::.:.::::: :.. XP_016 MTVRNIASICNMGTNASALEKDIGPEQFP-INEHYFGLVNFGNTCYCNSV 10 20 30 40 120 130 140 150 160 170 pF1KB4 VQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSM---DKTSSSIPPIILL .: . ... . : .... . . . . : ::: :. : . ::: .. XP_016 LQALYFCRPFRENVLAY------KAQQKKKENLLTCLADLFHSIATQKKKVGVIPPKKFI 50 60 70 80 90 100 180 190 200 210 220 230 pF1KB4 QFLHMAFPQFAEKGEQGQYLQQDANECWIQMMR----VLQQKLEAIEDDSVKETDSSSAS . :. : .:.::::.: .. .::.. . .... .. . . XP_016 SRLRKENDLF------DNYMQQDAHEFLNYLLNTIADILQEEKKQEKQNGKLKNGNMNEP 110 120 130 140 150 240 250 260 270 280 pF1KB4 AATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYL-----F : . . . . . ..: . . .: . : :.. :. :.:: ..:... : XP_016 AENNKPELTWVHEIFQGTLTNETRCLNCET--VSSKDEDFLDLSVDVEQNTSITHCLRDF 160 170 180 190 200 210 290 300 310 320 330 340 pF1KB4 TGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDV .. . : : : . : ....:: :.... :: : :. .:. : XP_016 SNTET-LCSEQKYYCETCCSKQEAQKRMRVKKLPMILALHLKRFKYMEQLHRYTKLSYRV 220 230 240 250 260 270 350 360 370 380 390 400 pF1KB4 KFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFA ::: : .. ::: . XP_016 VFPLELRLF------------------------------NTS-----------------S 280 410 420 430 440 450 460 pF1KB4 DDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLS : .. . .::: ::..: : . . :::.. :: .. :. :::: : . XP_016 DAVNLDR--MYDLVAVVVHCGSGPNRGHYITIVK-SHGFWLLFDDDIVEVGLQIILQ 290 300 310 320 330 340 470 480 490 pF1KB4 GGGDWHIAYVLLYGPRRVEIMEEESEQ >>NP_001127695 (OMIM: 612849) ubiquitin carboxyl-termina (359 aa) initn: 241 init1: 83 opt: 185 Z-score: 197.3 bits: 45.5 E(85289): 0.0003 Smith-Waterman score: 208; 21.9% identity (47.4% similar) in 411 aa overlap (90-483:14-358) 60 70 80 90 100 110 pF1KB4 NIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNAT .:. ::. : ::.:.::::: :.. NP_001 MNCFQGTNASALEKDIGPEQFP-INEHYFGLVNFGNTCYCNSV 10 20 30 40 120 130 140 150 160 170 pF1KB4 VQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSM---DKTSSSIPPIILL .: . ... . : .... . . . . : ::: :. : . ::: .. NP_001 LQALYFCRPFRENVLAY------KAQQKKKENLLTCLADLFHSIATQKKKVGVIPPKKFI 50 60 70 80 90 180 190 200 210 220 230 pF1KB4 QFLHMAFPQFAEKGEQGQYLQQDANECWIQMMR----VLQQKLEAIEDDSVKETDSSSAS . :. : .:.::::.: .. .::.. . .... .. . . NP_001 SRLRKENDLF------DNYMQQDAHEFLNYLLNTIADILQEEKKQEKQNGKLKNGNMNEP 100 110 120 130 140 150 240 250 260 270 280 pF1KB4 AATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYL-----F : . . . . . ..: . . .: . : :.. :. :.:: ..:... : NP_001 AENNKPELTWVHEIFQGTLTNETRCLNCET--VSSKDEDFLDLSVDVEQNTSITHCLRDF 160 170 180 190 200 290 300 310 320 330 340 pF1KB4 TGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDV .. . : : : . : ....:: :.... :: : :. .:. : NP_001 SNTET-LCSEQKYYCETCCSKQEAQKRMRVKKLPMILALHLKRFKYMEQLHRYTKLSYRV 210 220 230 240 250 260 350 360 370 380 390 400 pF1KB4 KFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFA ::: : .. ::: . NP_001 VFPLELRLF------------------------------NTS-----------------S 270 280 410 420 430 440 450 460 pF1KB4 DDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLS : .. . .::: ::..: : . . :::.. :: .. :. :::: : . . : .. NP_001 DAVNLDR--MYDLVAVVVHCGSGPNRGHYITIVK-SHGFWLLFDDDIVEKIDAQAIEEFY 290 300 310 320 330 470 480 490 pF1KB4 G-----GGDWHIAYVLLYGPRRVEIMEEESEQ : . . . .:.:.: : NP_001 GLTSDISKNSESGYILFYQSRE 340 350 >>NP_073743 (OMIM: 612849) ubiquitin carboxyl-terminal h (366 aa) initn: 241 init1: 83 opt: 185 Z-score: 197.2 bits: 45.5 E(85289): 0.0003 Smith-Waterman score: 208; 21.9% identity (47.4% similar) in 411 aa overlap (90-483:21-365) 60 70 80 90 100 110 pF1KB4 NIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNAT .:. ::. : ::.:.::::: :.. NP_073 MTVRNIASICNMGTNASALEKDIGPEQFP-INEHYFGLVNFGNTCYCNSV 10 20 30 40 120 130 140 150 160 170 pF1KB4 VQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSM---DKTSSSIPPIILL .: . ... . : .... . . . . : ::: :. : . ::: .. NP_073 LQALYFCRPFRENVLAY------KAQQKKKENLLTCLADLFHSIATQKKKVGVIPPKKFI 50 60 70 80 90 100 180 190 200 210 220 230 pF1KB4 QFLHMAFPQFAEKGEQGQYLQQDANECWIQMMR----VLQQKLEAIEDDSVKETDSSSAS . :. : .:.::::.: .. .::.. . .... .. . . NP_073 SRLRKENDLF------DNYMQQDAHEFLNYLLNTIADILQEEKKQEKQNGKLKNGNMNEP 110 120 130 140 150 240 250 260 270 280 pF1KB4 AATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYL-----F : . . . . . ..: . . .: . : :.. :. :.:: ..:... : NP_073 AENNKPELTWVHEIFQGTLTNETRCLNCET--VSSKDEDFLDLSVDVEQNTSITHCLRDF 160 170 180 190 200 210 290 300 310 320 330 340 pF1KB4 TGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDV .. . : : : . : ....:: :.... :: : :. .:. : NP_073 SNTET-LCSEQKYYCETCCSKQEAQKRMRVKKLPMILALHLKRFKYMEQLHRYTKLSYRV 220 230 240 250 260 270 350 360 370 380 390 400 pF1KB4 KFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFA ::: : .. ::: . NP_073 VFPLELRLF------------------------------NTS-----------------S 280 410 420 430 440 450 460 pF1KB4 DDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLS : .. . .::: ::..: : . . :::.. :: .. :. :::: : . . : .. NP_073 DAVNLDR--MYDLVAVVVHCGSGPNRGHYITIVK-SHGFWLLFDDDIVEKIDAQAIEEFY 290 300 310 320 330 340 470 480 490 pF1KB4 G-----GGDWHIAYVLLYGPRRVEIMEEESEQ : . . . .:.:.: : NP_073 GLTSDISKNSESGYILFYQSRE 350 360 >>NP_004642 (OMIM: 300050) ubiquitin carboxyl-terminal h (963 aa) initn: 234 init1: 141 opt: 190 Z-score: 196.9 bits: 46.9 E(85289): 0.00032 Smith-Waterman score: 190; 27.0% identity (54.0% similar) in 215 aa overlap (69-266:271-477) 40 50 60 70 80 90 pF1KB4 VQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKT-VFVEDMTEEQL :..: . :::. :. ..:.::. NP_004 RLWAKNSEGSLDRLYDTHITVLDAALETGQLIIMETRKKDGTWPSAQLHVMNNNMSEEDE 250 260 270 280 290 300 100 110 120 130 140 150 pF1KB4 A-SAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKR--YAGALRASGEMASAQYITA ... ::::::::::.::...::. .::.: . . : : . .. :. NP_004 DFKGQPGICGLTNLGNTCFMNSALQCLSNVPQLTEYFLNNCYLEELNFRNPLGMKGEIAE 310 320 330 340 350 360 160 170 180 190 200 210 pF1KB4 ALRDLFDSM--DKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQ : :: . . : .: .. . :.: :: : : :.:..: .. :. NP_004 AYADLVKQAWSGHHRSIVPHVFKNKVGHFA-SQF-----LG-YQQHDSQELLSFLLDGLH 370 380 390 400 410 220 230 240 250 260 pF1KB4 QKLEAIED-------DSVKETDSSSASAATPSKKKS----LIDQFFGVEFETTMKCTESE . :. .. :.. . :. :. : ..:. ..: : :. :..:. : . NP_004 EDLNRVKKKEYVELCDAAGRPDQEVAQEAWQNHKRRNDSVIVDTFHGL-FKSTLVCPDCG 420 430 440 450 460 470 270 280 290 300 310 320 pF1KB4 EEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLP . :: NP_004 NVSVTFDPFCYLSVPLPISHKRVLEVFFIPMDPRRKPEQHRLVVPKKGKISDLCVALSKH 480 490 500 510 520 530 >>XP_006719781 (OMIM: 604731) PREDICTED: ubiquitin carbo (775 aa) initn: 135 init1: 135 opt: 185 Z-score: 193.0 bits: 45.8 E(85289): 0.00052 Smith-Waterman score: 185; 27.5% identity (51.5% similar) in 200 aa overlap (82-266:266-457) 60 70 80 90 100 110 pF1KB4 TLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLG :: . :..: . . :::.::: XP_006 STLPKISPSSLSNNYNNMNNRNVKNSNYCLPSYTAYKNYDYSEPGRNNEQPGLCGLSNLG 240 250 260 270 280 290 120 130 140 150 160 pF1KB4 NTCYMNATVQCIRSVPELKDAL--KRYAGALRASGEMASAQYITAALRDLFDSM--DKTS :::.::...::. ..: : . . .: : .. .. :. . .:. .: : : XP_006 NTCFMNSAIQCLSNTPPLTEYFLNDKYQEELNFDNPLGMRGEIAKSYAELIKQMWSGKFS 300 310 320 330 340 350 170 180 190 200 210 220 pF1KB4 SSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIED------- : . : ..: :::. : : ::: .: .. :.. :. :. XP_006 YVTPRAFKTQVGRFA-PQFS--G----YQQQDCQELLAFLLDGLHEDLNRIRKKPYIQLK 360 370 380 390 400 230 240 250 260 270 pF1KB4 DSVKETDSSSASAATPSKKKS----LIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLS :. . :. : : .. : ..: : :. :..:. : : . :: XP_006 DADGRPDKVVAEEAWENHLKRNDSIIVDIFHGL-FKSTLVCPECAKISVTFDPFCYLTLP 410 420 430 440 450 460 280 290 300 310 320 330 pF1KB4 CFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEK XP_006 LPMKKERTLEVYLVRMDPLTKPMQYKVVVPKIGNILDLCTALSALSGIPADKMIVTDIYN 470 480 490 500 510 520 >>XP_016875774 (OMIM: 604731) PREDICTED: ubiquitin carbo (860 aa) initn: 206 init1: 135 opt: 185 Z-score: 192.4 bits: 45.9 E(85289): 0.00056 Smith-Waterman score: 185; 27.5% identity (51.5% similar) in 200 aa overlap (82-266:145-336) 60 70 80 90 100 110 pF1KB4 TLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLG :: . :..: . . :::.::: XP_016 STLPKISPSSLSNNYNNMNNRNVKNSNYCLPSYTAYKNYDYSEPGRNNEQPGLCGLSNLG 120 130 140 150 160 170 120 130 140 150 160 pF1KB4 NTCYMNATVQCIRSVPELKDAL--KRYAGALRASGEMASAQYITAALRDLFDSM--DKTS :::.::...::. ..: : . . .: : .. .. :. . .:. .: : : XP_016 NTCFMNSAIQCLSNTPPLTEYFLNDKYQEELNFDNPLGMRGEIAKSYAELIKQMWSGKFS 180 190 200 210 220 230 170 180 190 200 210 220 pF1KB4 SSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIED------- : . : ..: :::. : : ::: .: .. :.. :. :. XP_016 YVTPRAFKTQVGRFA-PQFS--G----YQQQDCQELLAFLLDGLHEDLNRIRKKPYIQLK 240 250 260 270 280 230 240 250 260 270 pF1KB4 DSVKETDSSSASAATPSKKKS----LIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLS :. . :. : : .. : ..: : :. :..:. : : . :: XP_016 DADGRPDKVVAEEAWENHLKRNDSIIVDIFHGL-FKSTLVCPECAKISVTFDPFCYLTLP 290 300 310 320 330 340 280 290 300 310 320 330 pF1KB4 CFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEK XP_016 LPMKKERTLEVYLVRMDPLTKPMQYKVVVPKIGNILDLCTALSALSGIPADKMIVTDIYN 350 360 370 380 390 400 494 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 05:59:55 2016 done: Sat Nov 5 05:59:56 2016 Total Scan time: 8.360 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]