FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB4679, 201 aa 1>>>pF1KB4679 201 - 201 aa - 201 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.6978+/-0.000847; mu= 9.8451+/- 0.051 mean_var=201.0270+/-42.509, 0's: 0 Z-trim(114.0): 76 B-trim: 853 in 1/53 Lambda= 0.090458 statistics sampled from 14494 (14576) to 14494 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.783), E-opt: 0.2 (0.448), width: 16 Scan time: 2.190 The best scores are: opt bits E(32554) CCDS58580.1 SRSF1 gene_id:6426|Hs108|chr17 ( 201) 1431 198.1 3e-51 CCDS11600.1 SRSF1 gene_id:6426|Hs108|chr17 ( 248) 1307 182.1 2.5e-46 CCDS9199.1 SRSF9 gene_id:8683|Hs108|chr12 ( 221) 865 124.3 5.5e-29 CCDS333.1 SRSF4 gene_id:6429|Hs108|chr1 ( 494) 464 72.4 5.1e-13 CCDS32109.1 SRSF5 gene_id:6430|Hs108|chr14 ( 272) 456 71.1 7.3e-13 CCDS13318.1 SRSF6 gene_id:6431|Hs108|chr20 ( 344) 449 70.3 1.6e-12 >>CCDS58580.1 SRSF1 gene_id:6426|Hs108|chr17 (201 aa) initn: 1431 init1: 1431 opt: 1431 Z-score: 1033.6 bits: 198.1 E(32554): 3e-51 Smith-Waterman score: 1431; 100.0% identity (100.0% similar) in 201 aa overlap (1-201:1-201) 10 20 30 40 50 60 pF1KB4 MSGGGVIRGPAGNNDCRIYVGNLPPDIRTKDIEDVFYKYGAIRDIDLKNRRGGPPFAFVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 MSGGGVIRGPAGNNDCRIYVGNLPPDIRTKDIEDVFYKYGAIRDIDLKNRRGGPPFAFVE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 FEDPRDAEDAVYGRDGYDYDGYRLRVEFPRSGRGTGRGGGGGGGGGAPRGRYGPPSRRSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 FEDPRDAEDAVYGRDGYDYDGYRLRVEFPRSGRGTGRGGGGGGGGGAPRGRYGPPSRRSE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 NRVVVSGLPPSGSWQDLKDHMREAGDVCYADVYRDGTGVVEFVRKEDMTYAVRKLDNTKF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 NRVVVSGLPPSGSWQDLKDHMREAGDVCYADVYRDGTGVVEFVRKEDMTYAVRKLDNTKF 130 140 150 160 170 180 190 200 pF1KB4 RSHEVGYTRILFFDQNWIQWS ::::::::::::::::::::: CCDS58 RSHEVGYTRILFFDQNWIQWS 190 200 >>CCDS11600.1 SRSF1 gene_id:6426|Hs108|chr17 (248 aa) initn: 1303 init1: 1303 opt: 1307 Z-score: 945.1 bits: 182.1 E(32554): 2.5e-46 Smith-Waterman score: 1307; 96.9% identity (98.4% similar) in 192 aa overlap (1-190:1-192) 10 20 30 40 50 60 pF1KB4 MSGGGVIRGPAGNNDCRIYVGNLPPDIRTKDIEDVFYKYGAIRDIDLKNRRGGPPFAFVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 MSGGGVIRGPAGNNDCRIYVGNLPPDIRTKDIEDVFYKYGAIRDIDLKNRRGGPPFAFVE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 FEDPRDAEDAVYGRDGYDYDGYRLRVEFPRSGRGTGRGGGGGGGGGAPRGRYGPPSRRSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 FEDPRDAEDAVYGRDGYDYDGYRLRVEFPRSGRGTGRGGGGGGGGGAPRGRYGPPSRRSE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 NRVVVSGLPPSGSWQDLKDHMREAGDVCYADVYRDGTGVVEFVRKEDMTYAVRKLDNTKF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 NRVVVSGLPPSGSWQDLKDHMREAGDVCYADVYRDGTGVVEFVRKEDMTYAVRKLDNTKF 130 140 150 160 170 180 190 200 pF1KB4 RSHE--VGYTRILFFDQNWIQWS :::: ..: :. CCDS11 RSHEGETAYIRVKVDGPRSPSYGRSRSRSRSRSRSRSRSNSRSRSYSPRRSRGSPRYSPR 190 200 210 220 230 240 >>CCDS9199.1 SRSF9 gene_id:8683|Hs108|chr12 (221 aa) initn: 507 init1: 462 opt: 865 Z-score: 633.9 bits: 124.3 E(32554): 5.5e-29 Smith-Waterman score: 875; 68.9% identity (82.4% similar) in 193 aa overlap (1-190:1-182) 10 20 30 40 50 60 pF1KB4 MSGGGVIRGPAGNNDCRIYVGNLPPDIRTKDIEDVFYKYGAIRDIDLKNRRGGPPFAFVE ::: . :: :..: :::::::: :.: ::.::.::::: ::.:.::::.: :::::. CCDS91 MSGWADERG--GEGDGRIYVGNLPTDVREKDLEDLFYKYGRIREIELKNRHGLVPFAFVR 10 20 30 40 50 70 80 90 100 110 pF1KB4 FEDPRDAEDAVYGRDGYDYDGYRLRVEFPRSGRGTGRGGGGGGGGGAPRG-RYGPPSRRS ::::::::::.:::.:::: ::::::::. :: :: ::: : :::.::: CCDS91 FEDPRDAEDAIYGRNGYDYGQCRLRVEFPRTY---------GGRGGWPRGGRNGPPTRRS 60 70 80 90 100 120 130 140 150 160 170 pF1KB4 ENRVVVSGLPPSGSWQDLKDHMREAGDVCYADVYRDGTGVVEFVRKEDMTYAVRKLDNTK . ::.:::::::::::::::::::::::::::: .::.:.::..::::: ::.::::.:: CCDS91 DFRVLVSGLPPSGSWQDLKDHMREAGDVCYADVQKDGVGMVEYLRKEDMEYALRKLDDTK 110 120 130 140 150 160 180 190 200 pF1KB4 FRSHE--VGYTRILFFDQNWIQWS ::::: ..: :. CCDS91 FRSHEGETSYIRVYPERSTSYGYSRSRSGSRGRDSPYQSRGSPHYFSPFRPY 170 180 190 200 210 220 >>CCDS333.1 SRSF4 gene_id:6429|Hs108|chr1 (494 aa) initn: 443 init1: 143 opt: 464 Z-score: 347.3 bits: 72.4 E(32554): 5.1e-13 Smith-Waterman score: 464; 45.4% identity (66.1% similar) in 174 aa overlap (17-185:3-170) 10 20 30 40 50 60 pF1KB4 MSGGGVIRGPAGNNDCRIYVGNLPPDIRTKDIEDVFYKYGAIRDIDLKNRRGGPPFAFVE :.:.: : . : .:.: : :: : ..:::: : ::: CCDS33 MPRVYIGRLSYQARERDVERFFKGYGKILEVDLKNGYG-----FVE 10 20 30 40 70 80 90 100 110 pF1KB4 FEDPRDAEDAVYGRDGYDYDGYRLRVEFPRSGRGTGRGGGGGGGGG---APRGRYGPPSR :.: :::.:::: .: : : :. :: :. : : :.: .: : . : .::::.: CCDS33 FDDLRDADDAVYELNGKDLCGERVIVEHARGPRRDGSYGSGRSGYGYRRSGRDKYGPPTR 50 60 70 80 90 100 120 130 140 150 160 170 pF1KB4 RSENRVVVSGLPPSGSWQDLKDHMREAGDVCYADVY--RDGTGVVEFVRKEDMTYAVRKL .: :..: .: :::::::.::.::.: :::.. : . ::.::: :: :..:: CCDS33 -TEYRLIVENLSSRCSWQDLKDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKL 110 120 130 140 150 160 180 190 200 pF1KB4 DNTKFRSHEVGYTRILFFDQNWIQWS :.:. .... CCDS33 DGTEVNGRKIRLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRS 170 180 190 200 210 220 >>CCDS32109.1 SRSF5 gene_id:6430|Hs108|chr14 (272 aa) initn: 474 init1: 175 opt: 456 Z-score: 344.5 bits: 71.1 E(32554): 7.3e-13 Smith-Waterman score: 456; 45.8% identity (67.8% similar) in 177 aa overlap (16-185:4-174) 10 20 30 40 50 60 pF1KB4 MSGGGVIRGPAGNNDCRIYVGNLPPDIRTKDIEDVFYKYGAIRDIDLKNRRGGPPFAFVE ::...: : : : ::.: : :: ::::::: :: :.::: CCDS32 MSGCRVFIGRLNPAAREKDVERFFKGYGRIRDIDLK--RG---FGFVE 10 20 30 40 70 80 90 100 110 pF1KB4 FEDPRDAEDAVYGRDGYDYDGYRLRVEFPRS-GRGTGRGGGGGG---GGGAPRG-RYGPP :::::::.:::: :: . . :. .: :. .:: ::: : . .. ::. : . : CCDS32 FEDPRDADDAVYELDGKELCSERVTIEHARARSRG-GRGRGRYSDRFSSRRPRNDRRNAP 50 60 70 80 90 100 120 130 140 150 160 170 pF1KB4 SRRSENRVVVSGLPPSGSWQDLKDHMREAGDVCYADVYRD--GTGVVEFVRKEDMTYAVR :.:::..: .: ::::::: ::.::.: .::..: . :::::. :. :.. CCDS32 PVRTENRLIVENLSSRVSWQDLKDFMRQAGEVTFADAHRPKLNEGVVEFASYGDLKNAIE 110 120 130 140 150 160 180 190 200 pF1KB4 KLDNTKFRSHEVGYTRILFFDQNWIQWS ::.. .. .... CCDS32 KLSGKEINGRKIKLIEGSKRHSRSRSRSRSRTRSSSRSRSRSRSRSRKSYSRSRSRSRSR 170 180 190 200 210 220 >>CCDS13318.1 SRSF6 gene_id:6431|Hs108|chr20 (344 aa) initn: 522 init1: 159 opt: 449 Z-score: 338.4 bits: 70.3 E(32554): 1.6e-12 Smith-Waterman score: 449; 45.6% identity (65.0% similar) in 180 aa overlap (17-185:3-176) 10 20 30 40 50 60 pF1KB4 MSGGGVIRGPAGNNDCRIYVGNLPPDIRTKDIEDVFYKYGAIRDIDLKNRRGGPPFAFVE :.:.: : ..: :::. : :: . ..:::: : ::: CCDS13 MPRVYIGRLSYNVREKDIQRFFSGYGRLLEVDLKNGYG-----FVE 10 20 30 40 70 80 90 100 110 pF1KB4 FEDPRDAEDAVYGRDGYDYDGYRLRVEF---PRSGR-GTGRGGGGGGGGGAPR---GR-- ::: :::.:::: .: . : :. :: :: : : . :. .:::: . : :: CCDS13 FEDSRDADDAVYELNGKELCGERVIVEHARGPRRDRDGYSYGSRSGGGGYSSRRTSGRDK 50 60 70 80 90 100 120 130 140 150 160 pF1KB4 YGPPSRRSENRVVVSGLPPSGSWQDLKDHMREAGDVCYADVYRDGT--GVVEFVRKEDMT :::: : .: :..: .: ::::::: ::.::.: :::.... : ::.:: :: CCDS13 YGPPVR-TEYRLIVENLSSRCSWQDLKDFMRQAGEVTYADAHKERTNEGVIEFRSYSDMK 110 120 130 140 150 160 170 180 190 200 pF1KB4 YAVRKLDNTKFRSHEVGYTRILFFDQNWIQWS :. :::.:.. .... CCDS13 RALDKLDGTEINGRNIRLIEDKPRTSHRRSYSGSRSRSRSRRRSRSRSRRSSRSRSRSIS 170 180 190 200 210 220 201 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 15:19:51 2016 done: Thu Nov 3 15:19:51 2016 Total Scan time: 2.190 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]