FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB4680, 522 aa 1>>>pF1KB4680 522 - 522 aa - 522 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.6652+/-0.0014; mu= 2.8529+/- 0.081 mean_var=280.6112+/-62.863, 0's: 0 Z-trim(108.8): 858 B-trim: 457 in 1/50 Lambda= 0.076563 statistics sampled from 9422 (10432) to 9422 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.674), E-opt: 0.2 (0.32), width: 16 Scan time: 3.540 The best scores are: opt bits E(32554) CCDS1622.1 ZBTB18 gene_id:10472|Hs108|chr1 ( 531) 3510 401.9 9.1e-112 CCDS45174.1 ZBTB42 gene_id:100128927|Hs108|chr14 ( 422) 791 101.5 2e-21 CCDS8034.1 ZBTB3 gene_id:79842|Hs108|chr11 ( 574) 700 91.6 2.6e-18 >>CCDS1622.1 ZBTB18 gene_id:10472|Hs108|chr1 (531 aa) initn: 3510 init1: 3510 opt: 3510 Z-score: 2120.1 bits: 401.9 E(32554): 9.1e-112 Smith-Waterman score: 3510; 100.0% identity (100.0% similar) in 522 aa overlap (1-522:10-531) 10 20 30 40 50 pF1KB4 MEFPDHSRHLLQCLSEQRHQGFLCDCTVLVGDAQFRAHRAVLASCSMYFHL ::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS16 MCPKGYEDSMEFPDHSRHLLQCLSEQRHQGFLCDCTVLVGDAQFRAHRAVLASCSMYFHL 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB4 FYKDQLDKRDIVHLNSDIVTAPAFALLLEFMYEGKLQFKDLPIEDVLAAASYLHMYDIVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS16 FYKDQLDKRDIVHLNSDIVTAPAFALLLEFMYEGKLQFKDLPIEDVLAAASYLHMYDIVK 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB4 VCKKKLKEKATTEADSTKKEEDASSCSDKVESLSDGSSHIAGDLPSDEDEGEDEKLNILP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS16 VCKKKLKEKATTEADSTKKEEDASSCSDKVESLSDGSSHIAGDLPSDEDEGEDEKLNILP 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB4 SKRDLAAEPGNMWMRLPSDSAGIPQAGGEAEPHATAAGKTVASPCSSTESLSQRSVTSVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS16 SKRDLAAEPGNMWMRLPSDSAGIPQAGGEAEPHATAAGKTVASPCSSTESLSQRSVTSVR 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB4 DSADVDCVLDLSVKSSLSGVENLNSSYFSSQDVLRSNLVQVKVEKEASCDESDVGTNDYD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS16 DSADVDCVLDLSVKSSLSGVENLNSSYFSSQDVLRSNLVQVKVEKEASCDESDVGTNDYD 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB4 MEHSTVKESVSTNNRVQYEPAHLAPLREDSVLRELDREDKASDDEMMTPESERVQVEGGM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS16 MEHSTVKESVSTNNRVQYEPAHLAPLREDSVLRELDREDKASDDEMMTPESERVQVEGGM 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB4 ESSLLPYVSNILSPAGQIFMCPLCNKVFPSPHILQIHLSTHFREQDGIRSKPAADVNVPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS16 ESSLLPYVSNILSPAGQIFMCPLCNKVFPSPHILQIHLSTHFREQDGIRSKPAADVNVPT 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB4 CSLCGKTFSCMYTLKRHERTHSGEKPYTCTQCGKSFQYSHNLSRHAVVHTREKPHACKWC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS16 CSLCGKTFSCMYTLKRHERTHSGEKPYTCTQCGKSFQYSHNLSRHAVVHTREKPHACKWC 430 440 450 460 470 480 480 490 500 510 520 pF1KB4 ERRFTQSGDLYRHIRKFHCELVNSLSVKSEALSLPTVRDWTLEDSSQELWK ::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS16 ERRFTQSGDLYRHIRKFHCELVNSLSVKSEALSLPTVRDWTLEDSSQELWK 490 500 510 520 530 >>CCDS45174.1 ZBTB42 gene_id:100128927|Hs108|chr14 (422 aa) initn: 1578 init1: 767 opt: 791 Z-score: 498.1 bits: 101.5 E(32554): 2e-21 Smith-Waterman score: 1267; 45.6% identity (63.1% similar) in 502 aa overlap (1-498:1-422) 10 20 30 40 50 pF1KB4 MEFPDHSRHLLQCLSEQRHQGFLCDCTVLVGDAQFRAHRAVLASCSMYFHLFYKDQ-LDK ::::.:. .:: : .::. :::::::::::::.: :::::::.::.::::::.:. . CCDS45 MEFPEHGGRLLGRLRQQRELGFLCDCTVLVGDARFPAHRAVLAACSVYFHLFYRDRPAGS 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB4 RDIVHLNSDIVTAPAFALLLEFMYEGKLQFKDLPIEDVLAAASYLHMYDIVKVCKKKLKE :: :.::.::::::::. ::.:::::.:....::.:::::::::::::::::::: .:.: CCDS45 RDTVRLNGDIVTAPAFGRLLDFMYEGRLDLRSLPVEDVLAAASYLHMYDIVKVCKGRLQE 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB4 KATTEADSTKKEEDASSCSDKVESLSDGSSHIAGDLPSDEDEGEDE-KLNILPSKRDLAA : :. ::. :. : :.. .. :. : CCDS45 K------------------DR--SLDPGNP-APGAEPAQPPCPWPVWTADLCPAARKAKL 130 140 150 180 190 200 210 220 230 pF1KB4 EPGNMWMRLPSDSAGIPQAGGEAEPHATAAGKTVASPCSSTESLSQRSVTSVRDSADVDC : .. :: ..: : ::. : . : CCDS45 PPFGVKAALPPRASGPP-------------------PCQVPE--------------ESDQ 160 170 180 240 250 260 270 280 290 pF1KB4 VLDLSVKSSLSGVENLNSSYFSSQDVLRSNLVQVKVEKEASCDESDVGTNDY--DMEHST .::::.::. . ::.. : :.. . :.. : . : CCDS45 ALDLSLKSGPR------QERVHPPCVLQTPL----------CSQRQPGAQPLVKDERDSL 190 200 210 220 230 300 310 320 330 340 350 pF1KB4 VKESVSTNNRVQYEPAHLAPLREDSVLRELDREDKASDDEMMTPESERVQVEGGMESSLL .. :...: . : . :. . : . : . :..... .: .: CCDS45 SEQEESSSSRSPHSPPKPPPVPAAKGLVVGLQPLPLSGEG-----SRELELGAGRLAS-- 240 250 260 270 280 360 370 380 390 400 410 pF1KB4 PYVSNILSPAGQIFMCPLCNKVFPSPHILQIHLSTHFREQDGIRSKPAADVNVPTCSLCG . :.:.: . .::::.:.::: :.::.:::.::::.:. :.. . : .::: ::: CCDS45 ---EDELGPGGPLCICPLCSKLFPSSHVLQLHLSAHFRERDSTRARLSPDGVAPTCPLCG 290 300 310 320 330 340 420 430 440 450 460 470 pF1KB4 KTFSCMYTLKRHERTHSGEKPYTCTQCGKSFQYSHNLSRHAVVHTREKPHACKWCERRFT ::::: ::::::::::::::::::.:::::::::::::::.:::::::::::.::::::: CCDS45 KTFSCTYTLKRHERTHSGEKPYTCVQCGKSFQYSHNLSRHTVVHTREKPHACRWCERRFT 350 360 370 380 390 400 480 490 500 510 520 pF1KB4 QSGDLYRHIRKFHCELVNSLSVKSEALSLPTVRDWTLEDSSQELWK ::::::::.::::: ::.:: : CCDS45 QSGDLYRHVRKFHCGLVKSLLV 410 420 >>CCDS8034.1 ZBTB3 gene_id:79842|Hs108|chr11 (574 aa) initn: 1055 init1: 294 opt: 700 Z-score: 442.2 bits: 91.6 E(32554): 2.6e-18 Smith-Waterman score: 915; 39.3% identity (59.8% similar) in 507 aa overlap (1-491:51-525) 10 20 30 pF1KB4 MEFPDHSRHLLQCLSEQRHQGFLCDCTVLV ::::.::..::: : ::: :::::::::.: CCDS80 KRSLLRGAVGRYRGATGGDLFWAPFPSWGTMEFPEHSQQLLQSLREQRSQGFLCDCTVMV 30 40 50 60 70 80 40 50 60 70 80 pF1KB4 GDAQFRAHRAVLASCSMYFHLFYKD-QLDKRDIVHLNSDIVTAPAFALLLEFMYEGKLQF :..:: :::::::::: .:.::::. .:::::.: ....:::::::.:::.::: :.: . CCDS80 GSTQFLAHRAVLASCSPFFQLFYKERELDKRDLVCIHNEIVTAPAFGLLLDFMYAGQLTL 90 100 110 120 130 140 90 100 110 120 130 140 pF1KB4 K-DLPIEDVLAAASYLHMYDIVKVCKKKLKEKATTEADSTKKEEDASSCSDKVESLSDGS . : :.:::::::::::: :::::::..:. .: .:::::::::...: ..: ::. : CCDS80 RGDTPVEDVLAAASYLHMNDIVKVCKRRLQARALAEADSTKKEEETNSQLPSLEFLSSTS 150 160 170 180 190 200 150 160 170 180 190 200 pF1KB4 SHIAGDLPSDEDEGE----DEKLNILPSKRDLAAEPGNMWMRLPSDSAGIPQAGGEAE-- .: : : :. . : . :: . : . : :..: : : :.. CCDS80 RGTQPSLASAETSGHWGKGEWKGSAAPSP--TVRPPDEPPM---SSGADTTQPGMEVDAP 210 220 230 240 250 210 220 230 240 250 pF1KB4 ----PHATAAGKTVASPCSSTESLSQRSVTSVRDSADVDCVLDLSVKSSLSGVENLNSSY :: .: ..::: ::::.. .: ...... . .:.: : :.: CCDS80 HLRAPHPPVADVSLASPSSSTETIPTNYFSSGISAVSLEPLPSLDV-----GPESLR--V 260 270 280 290 300 260 270 280 290 300 310 pF1KB4 FSSQDVLRSNLVQVKVEKEASCDESDVGTNDYDMEHSTVKESVSTNNRVQYEPAHLAPLR .: .. .: :: : . :. : .. . : :.:. .. CCDS80 VEPKDP--GGPLQ-GFYPPASAPTS---------APAPVSAPVPSQAPAPAE-AELVQVK 310 320 330 340 350 320 330 340 350 360 370 pF1KB4 EDSVLRELDREDKASDDEMMTPESERVQVEGGMESSLLPYVSNILSPAGQIFMCPLCNKV .... :.: .::.. . : ::. :: . : . . : . ..: CCDS80 VEAIVIS-DEETDVSDEQPQGP--ERAFPSGGAVYGAQPSQPEAFEDPGAAGL----EEV 360 370 380 390 400 380 390 400 410 420 430 pF1KB4 FPSPHILQI--HLSTHFREQDGIRSKPAADVNVPT-CSLCGKTF-SCMYTLKRHERTHSG :: :.: :: :. : . . .:. :: . : : CCDS80 GPSDHFLPTDPHLPYHLLPGAGQYHRGLVTSPLPAPASLHEPLYLSSEYEAAPGSFGVFT 410 420 430 440 450 460 440 450 460 470 480 490 pF1KB4 EKPYTCTQCGKSFQYSHNLSRHAVVHTREKPHACKWCERRFTQSGDLYRHIRKFHCELVN : :: :::.:. :..: :::.:::::.:. :..: : .:::::::::::: : : CCDS80 EDVPTCKTCGKTFSCSYTLRRHATVHTRERPYECRYCLRSYTQSGDLYRHIRKAHNEDLA 470 480 490 500 510 520 500 510 520 pF1KB4 SLSVKSEALSLPTVRDWTLEDSSQELWK CCDS80 KRSKPDPEVGPLLGVQPLPGSPTADRQSSSGGGPPKDFVLAPKTNI 530 540 550 560 570 522 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 15:21:04 2016 done: Thu Nov 3 15:21:04 2016 Total Scan time: 3.540 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]