FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB4680, 522 aa
1>>>pF1KB4680 522 - 522 aa - 522 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.5710+/-0.000576; mu= 4.0850+/- 0.035
mean_var=411.1585+/-99.123, 0's: 0 Z-trim(116.0): 1595 B-trim: 1380 in 1/52
Lambda= 0.063251
statistics sampled from 24646 (26811) to 24646 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.672), E-opt: 0.2 (0.314), width: 16
Scan time: 10.880
The best scores are: opt bits E(85289)
XP_005273063 (OMIM: 608433,612337) PREDICTED: zinc ( 522) 3510 335.6 2.2e-91
XP_016855549 (OMIM: 608433,612337) PREDICTED: zinc ( 522) 3510 335.6 2.2e-91
NP_006343 (OMIM: 608433,612337) zinc finger and BT ( 522) 3510 335.6 2.2e-91
NP_001265125 (OMIM: 608433,612337) zinc finger and ( 522) 3510 335.6 2.2e-91
NP_991331 (OMIM: 608433,612337) zinc finger and BT ( 531) 3510 335.6 2.2e-91
XP_016876400 (OMIM: 613915,616248) PREDICTED: zinc ( 422) 791 87.3 9.7e-17
NP_001131073 (OMIM: 613915,616248) zinc finger and ( 422) 791 87.3 9.7e-17
NP_001311067 (OMIM: 604084) zinc finger and BTB do ( 740) 447 56.3 3.7e-07
XP_005246043 (OMIM: 604084) PREDICTED: zinc finger ( 747) 447 56.3 3.7e-07
XP_006723763 (OMIM: 614639) PREDICTED: zinc finger ( 589) 418 53.5 2e-06
XP_005260253 (OMIM: 614639) PREDICTED: zinc finger ( 589) 418 53.5 2e-06
XP_005260252 (OMIM: 614639) PREDICTED: zinc finger ( 589) 418 53.5 2e-06
NP_079500 (OMIM: 614639) zinc finger and BTB domai ( 589) 418 53.5 2e-06
XP_005260255 (OMIM: 614639) PREDICTED: zinc finger ( 589) 418 53.5 2e-06
XP_011526850 (OMIM: 614639) PREDICTED: zinc finger ( 589) 418 53.5 2e-06
XP_005260254 (OMIM: 614639) PREDICTED: zinc finger ( 589) 418 53.5 2e-06
NP_055687 (OMIM: 616590) zinc finger and BTB domai ( 677) 387 50.8 1.6e-05
XP_005251691 (OMIM: 616590) PREDICTED: zinc finger ( 677) 387 50.8 1.6e-05
XP_011511718 (OMIM: 616238) PREDICTED: zinc finger ( 643) 376 49.7 3e-05
XP_011524172 (OMIM: 616591) PREDICTED: zinc finger ( 619) 343 46.7 0.00024
XP_005258286 (OMIM: 616591) PREDICTED: zinc finger ( 619) 343 46.7 0.00024
NP_001305770 (OMIM: 616591) zinc finger and BTB do ( 619) 343 46.7 0.00024
XP_011524173 (OMIM: 616591) PREDICTED: zinc finger ( 619) 343 46.7 0.00024
NP_001034449 (OMIM: 616591) zinc finger and BTB do ( 619) 343 46.7 0.00024
XP_016881098 (OMIM: 616591) PREDICTED: zinc finger ( 619) 343 46.7 0.00024
XP_011524171 (OMIM: 616591) PREDICTED: zinc finger ( 627) 343 46.7 0.00024
XP_016881097 (OMIM: 616591) PREDICTED: zinc finger ( 627) 343 46.7 0.00024
XP_011524168 (OMIM: 616591) PREDICTED: zinc finger ( 628) 343 46.7 0.00024
XP_011524165 (OMIM: 616591) PREDICTED: zinc finger ( 628) 343 46.7 0.00024
XP_011524169 (OMIM: 616591) PREDICTED: zinc finger ( 628) 343 46.7 0.00024
XP_011524166 (OMIM: 616591) PREDICTED: zinc finger ( 628) 343 46.7 0.00024
XP_011524167 (OMIM: 616591) PREDICTED: zinc finger ( 628) 343 46.7 0.00024
XP_016881096 (OMIM: 616591) PREDICTED: zinc finger ( 628) 343 46.7 0.00024
XP_016881095 (OMIM: 616591) PREDICTED: zinc finger ( 628) 343 46.7 0.00024
XP_011524163 (OMIM: 616591) PREDICTED: zinc finger ( 668) 343 46.8 0.00025
XP_016881094 (OMIM: 616591) PREDICTED: zinc finger ( 668) 343 46.8 0.00025
XP_011524471 (OMIM: 604760) PREDICTED: zinc finger (1540) 347 47.7 0.00031
XP_011524470 (OMIM: 604760) PREDICTED: zinc finger (1560) 347 47.7 0.00031
XP_011524468 (OMIM: 604760) PREDICTED: zinc finger (1706) 347 47.7 0.00032
XP_005266819 (OMIM: 604760) PREDICTED: zinc finger (1790) 347 47.8 0.00033
XP_011524467 (OMIM: 604760) PREDICTED: zinc finger (1845) 347 47.8 0.00034
NP_031371 (OMIM: 604760) zinc finger protein 236 i (1845) 347 47.8 0.00034
NP_001293018 (OMIM: 604760) zinc finger protein 23 (1847) 347 47.8 0.00034
XP_016878339 (OMIM: 604191) PREDICTED: zinc finger ( 479) 326 45.0 0.00061
XP_006720897 (OMIM: 604191) PREDICTED: zinc finger ( 479) 326 45.0 0.00061
XP_006720896 (OMIM: 604191) PREDICTED: zinc finger ( 598) 326 45.1 0.00069
XP_006720895 (OMIM: 604191) PREDICTED: zinc finger ( 644) 326 45.2 0.00072
XP_006720894 (OMIM: 604191) PREDICTED: zinc finger ( 670) 326 45.2 0.00074
XP_011520646 (OMIM: 604191) PREDICTED: zinc finger ( 683) 326 45.2 0.00074
NP_005732 (OMIM: 604191) zinc finger protein 263 [ ( 683) 326 45.2 0.00074
>>XP_005273063 (OMIM: 608433,612337) PREDICTED: zinc fin (522 aa)
initn: 3510 init1: 3510 opt: 3510 Z-score: 1761.6 bits: 335.6 E(85289): 2.2e-91
Smith-Waterman score: 3510; 100.0% identity (100.0% similar) in 522 aa overlap (1-522:1-522)
10 20 30 40 50 60
pF1KB4 MEFPDHSRHLLQCLSEQRHQGFLCDCTVLVGDAQFRAHRAVLASCSMYFHLFYKDQLDKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MEFPDHSRHLLQCLSEQRHQGFLCDCTVLVGDAQFRAHRAVLASCSMYFHLFYKDQLDKR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 DIVHLNSDIVTAPAFALLLEFMYEGKLQFKDLPIEDVLAAASYLHMYDIVKVCKKKLKEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DIVHLNSDIVTAPAFALLLEFMYEGKLQFKDLPIEDVLAAASYLHMYDIVKVCKKKLKEK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 ATTEADSTKKEEDASSCSDKVESLSDGSSHIAGDLPSDEDEGEDEKLNILPSKRDLAAEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ATTEADSTKKEEDASSCSDKVESLSDGSSHIAGDLPSDEDEGEDEKLNILPSKRDLAAEP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 GNMWMRLPSDSAGIPQAGGEAEPHATAAGKTVASPCSSTESLSQRSVTSVRDSADVDCVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GNMWMRLPSDSAGIPQAGGEAEPHATAAGKTVASPCSSTESLSQRSVTSVRDSADVDCVL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 DLSVKSSLSGVENLNSSYFSSQDVLRSNLVQVKVEKEASCDESDVGTNDYDMEHSTVKES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DLSVKSSLSGVENLNSSYFSSQDVLRSNLVQVKVEKEASCDESDVGTNDYDMEHSTVKES
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 VSTNNRVQYEPAHLAPLREDSVLRELDREDKASDDEMMTPESERVQVEGGMESSLLPYVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VSTNNRVQYEPAHLAPLREDSVLRELDREDKASDDEMMTPESERVQVEGGMESSLLPYVS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 NILSPAGQIFMCPLCNKVFPSPHILQIHLSTHFREQDGIRSKPAADVNVPTCSLCGKTFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NILSPAGQIFMCPLCNKVFPSPHILQIHLSTHFREQDGIRSKPAADVNVPTCSLCGKTFS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 CMYTLKRHERTHSGEKPYTCTQCGKSFQYSHNLSRHAVVHTREKPHACKWCERRFTQSGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CMYTLKRHERTHSGEKPYTCTQCGKSFQYSHNLSRHAVVHTREKPHACKWCERRFTQSGD
430 440 450 460 470 480
490 500 510 520
pF1KB4 LYRHIRKFHCELVNSLSVKSEALSLPTVRDWTLEDSSQELWK
::::::::::::::::::::::::::::::::::::::::::
XP_005 LYRHIRKFHCELVNSLSVKSEALSLPTVRDWTLEDSSQELWK
490 500 510 520
>>XP_016855549 (OMIM: 608433,612337) PREDICTED: zinc fin (522 aa)
initn: 3510 init1: 3510 opt: 3510 Z-score: 1761.6 bits: 335.6 E(85289): 2.2e-91
Smith-Waterman score: 3510; 100.0% identity (100.0% similar) in 522 aa overlap (1-522:1-522)
10 20 30 40 50 60
pF1KB4 MEFPDHSRHLLQCLSEQRHQGFLCDCTVLVGDAQFRAHRAVLASCSMYFHLFYKDQLDKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEFPDHSRHLLQCLSEQRHQGFLCDCTVLVGDAQFRAHRAVLASCSMYFHLFYKDQLDKR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 DIVHLNSDIVTAPAFALLLEFMYEGKLQFKDLPIEDVLAAASYLHMYDIVKVCKKKLKEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DIVHLNSDIVTAPAFALLLEFMYEGKLQFKDLPIEDVLAAASYLHMYDIVKVCKKKLKEK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 ATTEADSTKKEEDASSCSDKVESLSDGSSHIAGDLPSDEDEGEDEKLNILPSKRDLAAEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ATTEADSTKKEEDASSCSDKVESLSDGSSHIAGDLPSDEDEGEDEKLNILPSKRDLAAEP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 GNMWMRLPSDSAGIPQAGGEAEPHATAAGKTVASPCSSTESLSQRSVTSVRDSADVDCVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GNMWMRLPSDSAGIPQAGGEAEPHATAAGKTVASPCSSTESLSQRSVTSVRDSADVDCVL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 DLSVKSSLSGVENLNSSYFSSQDVLRSNLVQVKVEKEASCDESDVGTNDYDMEHSTVKES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLSVKSSLSGVENLNSSYFSSQDVLRSNLVQVKVEKEASCDESDVGTNDYDMEHSTVKES
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 VSTNNRVQYEPAHLAPLREDSVLRELDREDKASDDEMMTPESERVQVEGGMESSLLPYVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VSTNNRVQYEPAHLAPLREDSVLRELDREDKASDDEMMTPESERVQVEGGMESSLLPYVS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 NILSPAGQIFMCPLCNKVFPSPHILQIHLSTHFREQDGIRSKPAADVNVPTCSLCGKTFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NILSPAGQIFMCPLCNKVFPSPHILQIHLSTHFREQDGIRSKPAADVNVPTCSLCGKTFS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 CMYTLKRHERTHSGEKPYTCTQCGKSFQYSHNLSRHAVVHTREKPHACKWCERRFTQSGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CMYTLKRHERTHSGEKPYTCTQCGKSFQYSHNLSRHAVVHTREKPHACKWCERRFTQSGD
430 440 450 460 470 480
490 500 510 520
pF1KB4 LYRHIRKFHCELVNSLSVKSEALSLPTVRDWTLEDSSQELWK
::::::::::::::::::::::::::::::::::::::::::
XP_016 LYRHIRKFHCELVNSLSVKSEALSLPTVRDWTLEDSSQELWK
490 500 510 520
>>NP_006343 (OMIM: 608433,612337) zinc finger and BTB do (522 aa)
initn: 3510 init1: 3510 opt: 3510 Z-score: 1761.6 bits: 335.6 E(85289): 2.2e-91
Smith-Waterman score: 3510; 100.0% identity (100.0% similar) in 522 aa overlap (1-522:1-522)
10 20 30 40 50 60
pF1KB4 MEFPDHSRHLLQCLSEQRHQGFLCDCTVLVGDAQFRAHRAVLASCSMYFHLFYKDQLDKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MEFPDHSRHLLQCLSEQRHQGFLCDCTVLVGDAQFRAHRAVLASCSMYFHLFYKDQLDKR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 DIVHLNSDIVTAPAFALLLEFMYEGKLQFKDLPIEDVLAAASYLHMYDIVKVCKKKLKEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 DIVHLNSDIVTAPAFALLLEFMYEGKLQFKDLPIEDVLAAASYLHMYDIVKVCKKKLKEK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 ATTEADSTKKEEDASSCSDKVESLSDGSSHIAGDLPSDEDEGEDEKLNILPSKRDLAAEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 ATTEADSTKKEEDASSCSDKVESLSDGSSHIAGDLPSDEDEGEDEKLNILPSKRDLAAEP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 GNMWMRLPSDSAGIPQAGGEAEPHATAAGKTVASPCSSTESLSQRSVTSVRDSADVDCVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 GNMWMRLPSDSAGIPQAGGEAEPHATAAGKTVASPCSSTESLSQRSVTSVRDSADVDCVL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 DLSVKSSLSGVENLNSSYFSSQDVLRSNLVQVKVEKEASCDESDVGTNDYDMEHSTVKES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 DLSVKSSLSGVENLNSSYFSSQDVLRSNLVQVKVEKEASCDESDVGTNDYDMEHSTVKES
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 VSTNNRVQYEPAHLAPLREDSVLRELDREDKASDDEMMTPESERVQVEGGMESSLLPYVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 VSTNNRVQYEPAHLAPLREDSVLRELDREDKASDDEMMTPESERVQVEGGMESSLLPYVS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 NILSPAGQIFMCPLCNKVFPSPHILQIHLSTHFREQDGIRSKPAADVNVPTCSLCGKTFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 NILSPAGQIFMCPLCNKVFPSPHILQIHLSTHFREQDGIRSKPAADVNVPTCSLCGKTFS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 CMYTLKRHERTHSGEKPYTCTQCGKSFQYSHNLSRHAVVHTREKPHACKWCERRFTQSGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 CMYTLKRHERTHSGEKPYTCTQCGKSFQYSHNLSRHAVVHTREKPHACKWCERRFTQSGD
430 440 450 460 470 480
490 500 510 520
pF1KB4 LYRHIRKFHCELVNSLSVKSEALSLPTVRDWTLEDSSQELWK
::::::::::::::::::::::::::::::::::::::::::
NP_006 LYRHIRKFHCELVNSLSVKSEALSLPTVRDWTLEDSSQELWK
490 500 510 520
>>NP_001265125 (OMIM: 608433,612337) zinc finger and BTB (522 aa)
initn: 3510 init1: 3510 opt: 3510 Z-score: 1761.6 bits: 335.6 E(85289): 2.2e-91
Smith-Waterman score: 3510; 100.0% identity (100.0% similar) in 522 aa overlap (1-522:1-522)
10 20 30 40 50 60
pF1KB4 MEFPDHSRHLLQCLSEQRHQGFLCDCTVLVGDAQFRAHRAVLASCSMYFHLFYKDQLDKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEFPDHSRHLLQCLSEQRHQGFLCDCTVLVGDAQFRAHRAVLASCSMYFHLFYKDQLDKR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 DIVHLNSDIVTAPAFALLLEFMYEGKLQFKDLPIEDVLAAASYLHMYDIVKVCKKKLKEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DIVHLNSDIVTAPAFALLLEFMYEGKLQFKDLPIEDVLAAASYLHMYDIVKVCKKKLKEK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 ATTEADSTKKEEDASSCSDKVESLSDGSSHIAGDLPSDEDEGEDEKLNILPSKRDLAAEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ATTEADSTKKEEDASSCSDKVESLSDGSSHIAGDLPSDEDEGEDEKLNILPSKRDLAAEP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 GNMWMRLPSDSAGIPQAGGEAEPHATAAGKTVASPCSSTESLSQRSVTSVRDSADVDCVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GNMWMRLPSDSAGIPQAGGEAEPHATAAGKTVASPCSSTESLSQRSVTSVRDSADVDCVL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 DLSVKSSLSGVENLNSSYFSSQDVLRSNLVQVKVEKEASCDESDVGTNDYDMEHSTVKES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLSVKSSLSGVENLNSSYFSSQDVLRSNLVQVKVEKEASCDESDVGTNDYDMEHSTVKES
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 VSTNNRVQYEPAHLAPLREDSVLRELDREDKASDDEMMTPESERVQVEGGMESSLLPYVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VSTNNRVQYEPAHLAPLREDSVLRELDREDKASDDEMMTPESERVQVEGGMESSLLPYVS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 NILSPAGQIFMCPLCNKVFPSPHILQIHLSTHFREQDGIRSKPAADVNVPTCSLCGKTFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NILSPAGQIFMCPLCNKVFPSPHILQIHLSTHFREQDGIRSKPAADVNVPTCSLCGKTFS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 CMYTLKRHERTHSGEKPYTCTQCGKSFQYSHNLSRHAVVHTREKPHACKWCERRFTQSGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CMYTLKRHERTHSGEKPYTCTQCGKSFQYSHNLSRHAVVHTREKPHACKWCERRFTQSGD
430 440 450 460 470 480
490 500 510 520
pF1KB4 LYRHIRKFHCELVNSLSVKSEALSLPTVRDWTLEDSSQELWK
::::::::::::::::::::::::::::::::::::::::::
NP_001 LYRHIRKFHCELVNSLSVKSEALSLPTVRDWTLEDSSQELWK
490 500 510 520
>>NP_991331 (OMIM: 608433,612337) zinc finger and BTB do (531 aa)
initn: 3510 init1: 3510 opt: 3510 Z-score: 1761.5 bits: 335.6 E(85289): 2.2e-91
Smith-Waterman score: 3510; 100.0% identity (100.0% similar) in 522 aa overlap (1-522:10-531)
10 20 30 40 50
pF1KB4 MEFPDHSRHLLQCLSEQRHQGFLCDCTVLVGDAQFRAHRAVLASCSMYFHL
:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_991 MCPKGYEDSMEFPDHSRHLLQCLSEQRHQGFLCDCTVLVGDAQFRAHRAVLASCSMYFHL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB4 FYKDQLDKRDIVHLNSDIVTAPAFALLLEFMYEGKLQFKDLPIEDVLAAASYLHMYDIVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_991 FYKDQLDKRDIVHLNSDIVTAPAFALLLEFMYEGKLQFKDLPIEDVLAAASYLHMYDIVK
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB4 VCKKKLKEKATTEADSTKKEEDASSCSDKVESLSDGSSHIAGDLPSDEDEGEDEKLNILP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_991 VCKKKLKEKATTEADSTKKEEDASSCSDKVESLSDGSSHIAGDLPSDEDEGEDEKLNILP
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB4 SKRDLAAEPGNMWMRLPSDSAGIPQAGGEAEPHATAAGKTVASPCSSTESLSQRSVTSVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_991 SKRDLAAEPGNMWMRLPSDSAGIPQAGGEAEPHATAAGKTVASPCSSTESLSQRSVTSVR
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB4 DSADVDCVLDLSVKSSLSGVENLNSSYFSSQDVLRSNLVQVKVEKEASCDESDVGTNDYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_991 DSADVDCVLDLSVKSSLSGVENLNSSYFSSQDVLRSNLVQVKVEKEASCDESDVGTNDYD
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB4 MEHSTVKESVSTNNRVQYEPAHLAPLREDSVLRELDREDKASDDEMMTPESERVQVEGGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_991 MEHSTVKESVSTNNRVQYEPAHLAPLREDSVLRELDREDKASDDEMMTPESERVQVEGGM
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB4 ESSLLPYVSNILSPAGQIFMCPLCNKVFPSPHILQIHLSTHFREQDGIRSKPAADVNVPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_991 ESSLLPYVSNILSPAGQIFMCPLCNKVFPSPHILQIHLSTHFREQDGIRSKPAADVNVPT
370 380 390 400 410 420
420 430 440 450 460 470
pF1KB4 CSLCGKTFSCMYTLKRHERTHSGEKPYTCTQCGKSFQYSHNLSRHAVVHTREKPHACKWC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_991 CSLCGKTFSCMYTLKRHERTHSGEKPYTCTQCGKSFQYSHNLSRHAVVHTREKPHACKWC
430 440 450 460 470 480
480 490 500 510 520
pF1KB4 ERRFTQSGDLYRHIRKFHCELVNSLSVKSEALSLPTVRDWTLEDSSQELWK
:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_991 ERRFTQSGDLYRHIRKFHCELVNSLSVKSEALSLPTVRDWTLEDSSQELWK
490 500 510 520 530
>>XP_016876400 (OMIM: 613915,616248) PREDICTED: zinc fin (422 aa)
initn: 1578 init1: 767 opt: 791 Z-score: 421.6 bits: 87.3 E(85289): 9.7e-17
Smith-Waterman score: 1267; 45.6% identity (63.1% similar) in 502 aa overlap (1-498:1-422)
10 20 30 40 50
pF1KB4 MEFPDHSRHLLQCLSEQRHQGFLCDCTVLVGDAQFRAHRAVLASCSMYFHLFYKDQ-LDK
::::.:. .:: : .::. :::::::::::::.: :::::::.::.::::::.:. .
XP_016 MEFPEHGGRLLGRLRQQRELGFLCDCTVLVGDARFPAHRAVLAACSVYFHLFYRDRPAGS
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB4 RDIVHLNSDIVTAPAFALLLEFMYEGKLQFKDLPIEDVLAAASYLHMYDIVKVCKKKLKE
:: :.::.::::::::. ::.:::::.:....::.:::::::::::::::::::: .:.:
XP_016 RDTVRLNGDIVTAPAFGRLLDFMYEGRLDLRSLPVEDVLAAASYLHMYDIVKVCKGRLQE
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB4 KATTEADSTKKEEDASSCSDKVESLSDGSSHIAGDLPSDEDEGEDE-KLNILPSKRDLAA
: :. ::. :. : :.. .. :. :
XP_016 K------------------DR--SLDPGNP-APGAEPAQPPCPWPVWTADLCPAARKAKL
130 140 150
180 190 200 210 220 230
pF1KB4 EPGNMWMRLPSDSAGIPQAGGEAEPHATAAGKTVASPCSSTESLSQRSVTSVRDSADVDC
: .. :: ..: : ::. : . :
XP_016 PPFGVKAALPPRASGPP-------------------PCQVPE--------------ESDQ
160 170 180
240 250 260 270 280 290
pF1KB4 VLDLSVKSSLSGVENLNSSYFSSQDVLRSNLVQVKVEKEASCDESDVGTNDY--DMEHST
.::::.::. . ::.. : :.. . :.. : . :
XP_016 ALDLSLKSGPR------QERVHPPCVLQTPL----------CSQRQPGAQPLVKDERDSL
190 200 210 220 230
300 310 320 330 340 350
pF1KB4 VKESVSTNNRVQYEPAHLAPLREDSVLRELDREDKASDDEMMTPESERVQVEGGMESSLL
.. :...: . : . :. . : . : . :..... .: .:
XP_016 SEQEESSSSRSPHSPPKPPPVPAAKGLVVGLQPLPLSGEG-----SRELELGAGRLAS--
240 250 260 270 280
360 370 380 390 400 410
pF1KB4 PYVSNILSPAGQIFMCPLCNKVFPSPHILQIHLSTHFREQDGIRSKPAADVNVPTCSLCG
. :.:.: . .::::.:.::: :.::.:::.::::.:. :.. . : .::: :::
XP_016 ---EDELGPGGPLCICPLCSKLFPSSHVLQLHLSAHFRERDSTRARLSPDGVAPTCPLCG
290 300 310 320 330 340
420 430 440 450 460 470
pF1KB4 KTFSCMYTLKRHERTHSGEKPYTCTQCGKSFQYSHNLSRHAVVHTREKPHACKWCERRFT
::::: ::::::::::::::::::.:::::::::::::::.:::::::::::.:::::::
XP_016 KTFSCTYTLKRHERTHSGEKPYTCVQCGKSFQYSHNLSRHTVVHTREKPHACRWCERRFT
350 360 370 380 390 400
480 490 500 510 520
pF1KB4 QSGDLYRHIRKFHCELVNSLSVKSEALSLPTVRDWTLEDSSQELWK
::::::::.::::: ::.:: :
XP_016 QSGDLYRHVRKFHCGLVKSLLV
410 420
>>NP_001131073 (OMIM: 613915,616248) zinc finger and BTB (422 aa)
initn: 1578 init1: 767 opt: 791 Z-score: 421.6 bits: 87.3 E(85289): 9.7e-17
Smith-Waterman score: 1267; 45.6% identity (63.1% similar) in 502 aa overlap (1-498:1-422)
10 20 30 40 50
pF1KB4 MEFPDHSRHLLQCLSEQRHQGFLCDCTVLVGDAQFRAHRAVLASCSMYFHLFYKDQ-LDK
::::.:. .:: : .::. :::::::::::::.: :::::::.::.::::::.:. .
NP_001 MEFPEHGGRLLGRLRQQRELGFLCDCTVLVGDARFPAHRAVLAACSVYFHLFYRDRPAGS
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB4 RDIVHLNSDIVTAPAFALLLEFMYEGKLQFKDLPIEDVLAAASYLHMYDIVKVCKKKLKE
:: :.::.::::::::. ::.:::::.:....::.:::::::::::::::::::: .:.:
NP_001 RDTVRLNGDIVTAPAFGRLLDFMYEGRLDLRSLPVEDVLAAASYLHMYDIVKVCKGRLQE
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB4 KATTEADSTKKEEDASSCSDKVESLSDGSSHIAGDLPSDEDEGEDE-KLNILPSKRDLAA
: :. ::. :. : :.. .. :. :
NP_001 K------------------DR--SLDPGNP-APGAEPAQPPCPWPVWTADLCPAARKAKL
130 140 150
180 190 200 210 220 230
pF1KB4 EPGNMWMRLPSDSAGIPQAGGEAEPHATAAGKTVASPCSSTESLSQRSVTSVRDSADVDC
: .. :: ..: : ::. : . :
NP_001 PPFGVKAALPPRASGPP-------------------PCQVPE--------------ESDQ
160 170 180
240 250 260 270 280 290
pF1KB4 VLDLSVKSSLSGVENLNSSYFSSQDVLRSNLVQVKVEKEASCDESDVGTNDY--DMEHST
.::::.::. . ::.. : :.. . :.. : . :
NP_001 ALDLSLKSGPR------QERVHPPCVLQTPL----------CSQRQPGAQPLVKDERDSL
190 200 210 220 230
300 310 320 330 340 350
pF1KB4 VKESVSTNNRVQYEPAHLAPLREDSVLRELDREDKASDDEMMTPESERVQVEGGMESSLL
.. :...: . : . :. . : . : . :..... .: .:
NP_001 SEQEESSSSRSPHSPPKPPPVPAAKGLVVGLQPLPLSGEG-----SRELELGAGRLAS--
240 250 260 270 280
360 370 380 390 400 410
pF1KB4 PYVSNILSPAGQIFMCPLCNKVFPSPHILQIHLSTHFREQDGIRSKPAADVNVPTCSLCG
. :.:.: . .::::.:.::: :.::.:::.::::.:. :.. . : .::: :::
NP_001 ---EDELGPGGPLCICPLCSKLFPSSHVLQLHLSAHFRERDSTRARLSPDGVAPTCPLCG
290 300 310 320 330 340
420 430 440 450 460 470
pF1KB4 KTFSCMYTLKRHERTHSGEKPYTCTQCGKSFQYSHNLSRHAVVHTREKPHACKWCERRFT
::::: ::::::::::::::::::.:::::::::::::::.:::::::::::.:::::::
NP_001 KTFSCTYTLKRHERTHSGEKPYTCVQCGKSFQYSHNLSRHTVVHTREKPHACRWCERRFT
350 360 370 380 390 400
480 490 500 510 520
pF1KB4 QSGDLYRHIRKFHCELVNSLSVKSEALSLPTVRDWTLEDSSQELWK
::::::::.::::: ::.:: :
NP_001 QSGDLYRHVRKFHCGLVKSLLV
410 420
>>NP_001311067 (OMIM: 604084) zinc finger and BTB domain (740 aa)
initn: 1318 init1: 260 opt: 447 Z-score: 249.5 bits: 56.3 E(85289): 3.7e-07
Smith-Waterman score: 513; 26.5% identity (53.0% similar) in 536 aa overlap (1-504:1-511)
10 20 30 40 50 60
pF1KB4 MEFPDHSRHLLQCLSEQRHQGFLCDCTVLVGDAQFRAHRAVLASCSMYFHLFYKDQLDKR
:.::.::.:.:. :..::. :.::::: .: ..:.::.::::.:: ::.... :: .
NP_001 MDFPQHSQHVLEQLNQQRQLGLLCDCTFVVDGVHFKAHKAVLAACSEYFKMLFVDQ---K
10 20 30 40 50
70 80 90 100 110 120
pF1KB4 DIVHLNSDIVTAPAFALLLEFMYEGKLQFKDLPIEDVLAAASYLHMYDIVKVCKKKLKEK
:.::: :: .: : . : :. . : . . .. . .: . ..
NP_001 DVVHL--DISNA---AGGDKRAKEEKVATSTLSRLEQAGRSTPIGPSRDLKEERGGQAQS
60 70 80 90 100 110
130 140 150 160 170
pF1KB4 ATTEADSTKKEEDASSCSDKVESLSDGSSHIAG-DLPSDEDEGEDEKLNILPSKRDLAAE
:.. :..:.: :: :: : .: .:. . . .:. ...... :... . :
NP_001 AASGAEQTEKA-DAPREPPPVELKPDPTSGMAAAEAEAALSESSEQEMEVEPARK--GEE
120 130 140 150 160
180 190 200 210 220 230
pF1KB4 PGNMWMRLPSDSAG---IPQAGGEAEPHATAAGKTVASPCSSTESLSQ--RSVTSVRDSA
. . ..:: . . :.. : .. : .. ..:.: .. . ..:...
NP_001 EQKEQEEQEEEGAGPAEVKEEGSQLE-NGEAPEENENEESAGTDSGQELGSEARGLRSGT
170 180 190 200 210 220
240 250 260 270 280
pF1KB4 DVDCVLDLSVKSSLSGVENLNSSYFSSQDVLRSNLVQVKVEKEASCDESDVGTND-----
: . . . : . :. .. . . . : ... :: :: : . . .:
NP_001 YGDRTESKAYGSVIHKCEDCGKEFTHTGNFKRHIRIHTG-EKPFSCRECSKAFSDPAACK
230 240 250 260 270 280
290 300 310 320 330 340
pF1KB4 -YDMEHSTVKESVSTNNRVQYEPAHLAPLREDSVLRELD-REDKASDDEMMTPESERVQ-
.. :: .: . .:. : :.. : : . . . . .: :
NP_001 AHEKTHSPLKPYGCEECGKSYRLISLLNLHKKRHSGEARYRCEDCGKLFTTSGNLKRHQL
290 300 310 320 330 340
350 360 370 380 390
pF1KB4 VEGGMESSLLPYVSNILS-PAGQI-----------FMCPLCNKVFPSPHILQIHLSTHFR
:..: . : . .: :.... :: :.: : . :. ::. :.
NP_001 VHSGEKPYQCDYCGRSFSDPTSKMRHLETHDTDKEHKCPHCDKKFNQVGNLKAHLKIHI-
350 360 370 380 390 400
400 410 420 430 440 450
pF1KB4 EQDGIRSKPAADVNVPTCSLCGKTFSCMYTLKRHERTHSGEKPYTCTQCGKSFQYSHNLS
:: : : ::: :. .:::: : :::::::.: .: ..: :.
NP_001 -ADG----PLK------CRECGKQFTTSGNLKRHLRIHSGEKPYVCIHCQRQFADPGALQ
410 420 430 440 450
460 470 480 490 500
pF1KB4 RHAVVHTREKPHACKWCERRFTQSGDLYRHIRK------FHCELVNSLSVKSEALSLPTV
::. .:: ::: : : . :::...: :.:. . :: .. :.: :.
NP_001 RHVRIHTGEKPCQCVMCGKAFTQASSLIAHVRQHTGEKPYVCERCGKRFVQSSQLANHIR
460 470 480 490 500 510
510 520
pF1KB4 RDWTLEDSSQELWK
NP_001 HHDNIRPHKCSVCSKAFVNVGDLSKHIIIHTGEKPYLCDKCGRGFNRVDNLRSHVKTVHQ
520 530 540 550 560 570
>>XP_005246043 (OMIM: 604084) PREDICTED: zinc finger and (747 aa)
initn: 1318 init1: 260 opt: 447 Z-score: 249.5 bits: 56.3 E(85289): 3.7e-07
Smith-Waterman score: 513; 26.5% identity (53.0% similar) in 536 aa overlap (1-504:1-511)
10 20 30 40 50 60
pF1KB4 MEFPDHSRHLLQCLSEQRHQGFLCDCTVLVGDAQFRAHRAVLASCSMYFHLFYKDQLDKR
:.::.::.:.:. :..::. :.::::: .: ..:.::.::::.:: ::.... :: .
XP_005 MDFPQHSQHVLEQLNQQRQLGLLCDCTFVVDGVHFKAHKAVLAACSEYFKMLFVDQ---K
10 20 30 40 50
70 80 90 100 110 120
pF1KB4 DIVHLNSDIVTAPAFALLLEFMYEGKLQFKDLPIEDVLAAASYLHMYDIVKVCKKKLKEK
:.::: :: .: : . : :. . : . . .. . .: . ..
XP_005 DVVHL--DISNA---AGGDKRAKEEKVATSTLSRLEQAGRSTPIGPSRDLKEERGGQAQS
60 70 80 90 100 110
130 140 150 160 170
pF1KB4 ATTEADSTKKEEDASSCSDKVESLSDGSSHIAG-DLPSDEDEGEDEKLNILPSKRDLAAE
:.. :..:.: :: :: : .: .:. . . .:. ...... :... . :
XP_005 AASGAEQTEKA-DAPREPPPVELKPDPTSGMAAAEAEAALSESSEQEMEVEPARK--GEE
120 130 140 150 160
180 190 200 210 220 230
pF1KB4 PGNMWMRLPSDSAG---IPQAGGEAEPHATAAGKTVASPCSSTESLSQ--RSVTSVRDSA
. . ..:: . . :.. : .. : .. ..:.: .. . ..:...
XP_005 EQKEQEEQEEEGAGPAEVKEEGSQLE-NGEAPEENENEESAGTDSGQELGSEARGLRSGT
170 180 190 200 210 220
240 250 260 270 280
pF1KB4 DVDCVLDLSVKSSLSGVENLNSSYFSSQDVLRSNLVQVKVEKEASCDESDVGTND-----
: . . . : . :. .. . . . : ... :: :: : . . .:
XP_005 YGDRTESKAYGSVIHKCEDCGKEFTHTGNFKRHIRIHTG-EKPFSCRECSKAFSDPAACK
230 240 250 260 270 280
290 300 310 320 330 340
pF1KB4 -YDMEHSTVKESVSTNNRVQYEPAHLAPLREDSVLRELD-REDKASDDEMMTPESERVQ-
.. :: .: . .:. : :.. : : . . . . .: :
XP_005 AHEKTHSPLKPYGCEECGKSYRLISLLNLHKKRHSGEARYRCEDCGKLFTTSGNLKRHQL
290 300 310 320 330 340
350 360 370 380 390
pF1KB4 VEGGMESSLLPYVSNILS-PAGQI-----------FMCPLCNKVFPSPHILQIHLSTHFR
:..: . : . .: :.... :: :.: : . :. ::. :.
XP_005 VHSGEKPYQCDYCGRSFSDPTSKMRHLETHDTDKEHKCPHCDKKFNQVGNLKAHLKIHI-
350 360 370 380 390 400
400 410 420 430 440 450
pF1KB4 EQDGIRSKPAADVNVPTCSLCGKTFSCMYTLKRHERTHSGEKPYTCTQCGKSFQYSHNLS
:: : : ::: :. .:::: : :::::::.: .: ..: :.
XP_005 -ADG----PLK------CRECGKQFTTSGNLKRHLRIHSGEKPYVCIHCQRQFADPGALQ
410 420 430 440 450
460 470 480 490 500
pF1KB4 RHAVVHTREKPHACKWCERRFTQSGDLYRHIRK------FHCELVNSLSVKSEALSLPTV
::. .:: ::: : : . :::...: :.:. . :: .. :.: :.
XP_005 RHVRIHTGEKPCQCVMCGKAFTQASSLIAHVRQHTGEKPYVCERCGKRFVQSSQLANHIR
460 470 480 490 500 510
510 520
pF1KB4 RDWTLEDSSQELWK
XP_005 HHDNIRPHKCSVCSKAFVNVGDLSKHIIIHTGEKPYLCDKCGRGFNRVDNLRSHVKTVHQ
520 530 540 550 560 570
>>XP_006723763 (OMIM: 614639) PREDICTED: zinc finger and (589 aa)
initn: 595 init1: 214 opt: 418 Z-score: 236.2 bits: 53.5 E(85289): 2e-06
Smith-Waterman score: 474; 25.7% identity (54.7% similar) in 536 aa overlap (1-489:8-498)
10 20 30 40 50
pF1KB4 MEFPDHSRHLLQCLSEQRHQGFLCDCTVLVGDAQFRAHRAVLASCSMYFHLFY
::. .: ::::. :.:::..: ::: :.: :.::. :: . : ::. .:
XP_006 MNNRKEDMEITSHYRHLLRELNEQRQHGVLCDVCVVVEGKVFKAHKNVLLGSSRYFKTLY
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB4 ---KDQLDKRDIVHLNSDIVTAPAFALLLEFMYEGKLQFKDLPIEDVLAAASYLHMYDIV
. .. ..:: ::::: .: ...::: ..: . . . .:..:::.:.: :::
XP_006 CQVQKTSEQATVTHL--DIVTAQGFKAIIDFMYSAHLALTSRNVIEVMSAASFLQMTDIV
70 80 90 100 110
120 130 140
pF1KB4 KVCKKKLKEKATTEADSTKKEEDA-----SSCSDKVESL---------------------
..:. .: : ..: : .: :...:.:
XP_006 QACHDFIKAALDISIKSDASDELAEFEIGASSSSSTEALISAVMAGRSISPWLARRTSPA
120 130 140 150 160 170
150 160 170 180 190
pF1KB4 -SDGSSHIAGDLPSDEDEGEDEKLNILPSKRDLAAEPGNMW--------MRLPSDSAGIP
:.:.: ::. . . :.... . :....: .: .:. ....
XP_006 NSSGDSAIASCHDGGSSYGKEDQEPKADGPDDVSSQP--LWPGDVGYGPLRIKEEQVSPS
180 190 200 210 220 230
200 210 220 230 240
pF1KB4 QAGGEAEPHAT-AAGKTVASPCSSTESLSQRSVTSVRDSADV-----DCVLDLSVKSS-L
: :: : : .: .. : :. .. . . . : . .. . : : : :: .
XP_006 QYGGSELPSAKDGAVQNSFSEQSAGDAWQPTGRRKNRKNKETVRHITQQVEDDSRASSPV
240 250 260 270 280 290
250 260 270 280 290 300
pF1KB4 SGVENLNSSYFSSQDVLRSNLVQVKVEKEASCDESDVGTNDYDMEHSTVKESVSTNNRVQ
. .. :::.: :: ....: . .: : . .. .. :.:.. .....
XP_006 PSFLPTSGWPFSSRD---SN-ADLSVTEASSSD----SRGERAELYAQVEEGL-LGGEAS
300 310 320 330 340
310 320 330 340 350 360
pF1KB4 YEPAHLAPLREDSVLRELDREDKASDDEMMTPESERVQVEGGMESSLLPYVSNILSPAGQ
: :.: ..:.. . . . .:. ..::: ...:. :.
XP_006 YLGPPLTPEKDDALHQATAVANLRA--ALMS------------KNSLLSLKADVLGDDGS
350 360 370 380 390
370 380 390 400 410 420
pF1KB4 IFMCPLCNKVFP-SPHILQIHLSTHFREQDGIRSKPAADVNVPTCSLCGKTFSCMYTLKR
... . .: . : :... : .:.. . : ::. . .:. :::
XP_006 LLF-----EYLPRGAHSLSLNEFTVIRKK----------FKCPYCSF-SAMHQCI--LKR
400 410 420 430
430 440 450 460 470 480
pF1KB4 HERTHSGEKPYTCTQCGKSFQYSHNLSRHAVVHTREKPHACKWCERRFTQSGDL-YRHIR
: :.:.::.:: : :::.: ....::..::...: ..:: : : : ..... ::
XP_006 HMRSHTGERPYPCEICGKKFTRREHMKRHTLVHSKDKKYVCKVCSRVFMSAASVGIRHGS
440 450 460 470 480 490
490 500 510 520
pF1KB4 KFHCELVNSLSVKSEALSLPTVRDWTLEDSSQELWK
. :
XP_006 RRHGVCTDCAGRGMAGPLDHGGGGGEGSPEALFPGDGPYLEDPEDPRGEAEELGEDDEGL
500 510 520 530 540 550
522 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 15:21:04 2016 done: Thu Nov 3 15:21:06 2016
Total Scan time: 10.880 Total Display time: 0.100
Function used was FASTA [36.3.4 Apr, 2011]