FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB4698, 883 aa 1>>>pF1KB4698 883 - 883 aa - 883 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.2086+/-0.000543; mu= 20.8336+/- 0.033 mean_var=65.7637+/-13.115, 0's: 0 Z-trim(106.1): 135 B-trim: 0 in 0/48 Lambda= 0.158154 statistics sampled from 14094 (14230) to 14094 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.501), E-opt: 0.2 (0.167), width: 16 Scan time: 11.360 The best scores are: opt bits E(85289) NP_000817 (OMIM: 138247) glutamate receptor 2 isof ( 883) 5797 1332.9 0 NP_001077088 (OMIM: 138247) glutamate receptor 2 i ( 883) 5738 1319.4 0 NP_001077089 (OMIM: 138247) glutamate receptor 2 i ( 836) 5486 1261.9 0 XP_016863606 (OMIM: 138247) PREDICTED: glutamate r ( 836) 5480 1260.5 0 XP_016863605 (OMIM: 138247) PREDICTED: glutamate r ( 836) 5480 1260.5 0 XP_016863603 (OMIM: 138247) PREDICTED: glutamate r ( 836) 5421 1247.1 0 XP_016863602 (OMIM: 138247) PREDICTED: glutamate r ( 836) 5421 1247.1 0 XP_016863604 (OMIM: 138247) PREDICTED: glutamate r ( 836) 5421 1247.1 0 XP_011541077 (OMIM: 138246) PREDICTED: glutamate r ( 884) 4537 1045.4 0 NP_001070711 (OMIM: 138246) glutamate receptor 4 i ( 884) 4482 1032.8 0 XP_006718886 (OMIM: 138246) PREDICTED: glutamate r ( 902) 4353 1003.4 0 NP_000820 (OMIM: 138246) glutamate receptor 4 isof ( 902) 4343 1001.1 0 NP_015564 (OMIM: 300699,305915) glutamate receptor ( 894) 4336 999.5 0 XP_005271575 (OMIM: 138246) PREDICTED: glutamate r ( 902) 4308 993.1 0 NP_000819 (OMIM: 300699,305915) glutamate receptor ( 894) 4278 986.3 0 NP_001107655 (OMIM: 138248) glutamate receptor 1 i ( 906) 4158 958.9 0 NP_000818 (OMIM: 138248) glutamate receptor 1 isof ( 906) 4127 951.8 0 XP_011535937 (OMIM: 138248) PREDICTED: glutamate r ( 886) 4115 949.1 0 NP_001244951 (OMIM: 138248) glutamate receptor 1 i ( 916) 4114 948.9 0 NP_001244950 (OMIM: 138248) glutamate receptor 1 i ( 916) 4083 941.8 0 XP_016873098 (OMIM: 138246) PREDICTED: glutamate r ( 814) 4037 931.3 0 XP_016864882 (OMIM: 138248) PREDICTED: glutamate r ( 837) 4005 924.0 0 NP_001244952 (OMIM: 138248) glutamate receptor 1 i ( 837) 3974 916.9 0 NP_001244949 (OMIM: 138248) glutamate receptor 1 i ( 811) 3870 893.2 0 XP_016873099 (OMIM: 138246) PREDICTED: glutamate r ( 771) 3834 884.9 0 XP_016864881 (OMIM: 138248) PREDICTED: glutamate r ( 846) 3822 882.2 0 XP_011541079 (OMIM: 138246) PREDICTED: glutamate r ( 732) 3666 846.6 0 XP_016873100 (OMIM: 138246) PREDICTED: glutamate r ( 732) 3666 846.6 0 XP_011541078 (OMIM: 138246) PREDICTED: glutamate r ( 732) 3666 846.6 0 NP_001244948 (OMIM: 138248) glutamate receptor 1 i ( 826) 3563 823.1 0 XP_011534080 (OMIM: 138244,611092) PREDICTED: glut ( 869) 2021 471.3 8.7e-132 NP_786944 (OMIM: 138244,611092) glutamate receptor ( 869) 2021 471.3 8.7e-132 XP_011534079 (OMIM: 138244,611092) PREDICTED: glut ( 892) 2021 471.3 8.9e-132 NP_001159719 (OMIM: 138244,611092) glutamate recep ( 892) 2021 471.3 8.9e-132 NP_068775 (OMIM: 138244,611092) glutamate receptor ( 908) 2021 471.3 9.1e-132 XP_005267002 (OMIM: 138244,611092) PREDICTED: glut ( 908) 2021 471.3 9.1e-132 XP_005267003 (OMIM: 138244,611092) PREDICTED: glut ( 859) 1995 465.4 5.3e-130 NP_000822 (OMIM: 138243) glutamate receptor ionotr ( 919) 1956 456.5 2.7e-127 XP_005261001 (OMIM: 138245) PREDICTED: glutamate r ( 903) 1945 454.0 1.5e-126 NP_783300 (OMIM: 138245) glutamate receptor ionotr ( 905) 1945 454.0 1.5e-126 NP_001317922 (OMIM: 138245) glutamate receptor ion ( 934) 1945 454.0 1.5e-126 NP_001307550 (OMIM: 138245) glutamate receptor ion ( 763) 1846 431.3 8.2e-120 NP_001106283 (OMIM: 138246) glutamate receptor 4 i ( 433) 1724 403.4 1.2e-111 NP_001070712 (OMIM: 138246) glutamate receptor 4 i ( 433) 1724 403.4 1.2e-111 XP_016866270 (OMIM: 138244,611092) PREDICTED: glut ( 707) 1661 389.1 3.9e-107 XP_011541089 (OMIM: 600282) PREDICTED: glutamate r ( 702) 1647 385.9 3.6e-106 XP_011541088 (OMIM: 600282) PREDICTED: glutamate r ( 714) 1647 385.9 3.6e-106 XP_011541086 (OMIM: 600282) PREDICTED: glutamate r ( 902) 1647 386.0 4.4e-106 NP_001269399 (OMIM: 600282) glutamate receptor ion ( 956) 1647 386.0 4.6e-106 NP_055434 (OMIM: 600282) glutamate receptor ionotr ( 956) 1647 386.0 4.6e-106 >>NP_000817 (OMIM: 138247) glutamate receptor 2 isoform (883 aa) initn: 5797 init1: 5797 opt: 5797 Z-score: 7143.1 bits: 1332.9 E(85289): 0 Smith-Waterman score: 5797; 100.0% identity (100.0% similar) in 883 aa overlap (1-883:1-883) 10 20 30 40 50 60 pF1KB4 MQKIMHISVLLSPVLWGLIFGVSSNSIQIGGLFPRGADQEYSAFRVGMVQFSTSEFRLTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 MQKIMHISVLLSPVLWGLIFGVSSNSIQIGGLFPRGADQEYSAFRVGMVQFSTSEFRLTP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 HIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 HIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTDG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 THPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVTAINV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 THPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVTAINV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 GNINNDKKDEMYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYHYIIANL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 GNINNDKKDEMYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYHYIIANL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 GFTDGDLLKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTTTIKYTSALT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 GFTDGDLLKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTTTIKYTSALT 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 YDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEGLSGNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 YDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEGLSGNI 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB4 KFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTELPSGNDTSGLENKTVVVTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 KFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTELPSGNDTSGLENKTVVVTT 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB4 ILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 ILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKI 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB4 WNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 WNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLD 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB4 PLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQSSESTNEFGIFNSLWF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 PLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQSSESTNEFGIFNSLWF 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB4 SLGAFMRQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 SLGAFMRQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDL 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB4 SKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 SKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGK 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB4 YAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLRTPVNLAVLKLSEQGVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 YAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLRTPVNLAVLKLSEQGVL 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB4 DKLKNKWWYDKGECGAKDSGSKEKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 DKLKNKWWYDKGECGAKDSGSKEKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSR 790 800 810 820 830 840 850 860 870 880 pF1KB4 AEAKRMKVAKNAQNINPSSSQNSQNFATYKEGYNVYGIESVKI ::::::::::::::::::::::::::::::::::::::::::: NP_000 AEAKRMKVAKNAQNINPSSSQNSQNFATYKEGYNVYGIESVKI 850 860 870 880 >>NP_001077088 (OMIM: 138247) glutamate receptor 2 isofo (883 aa) initn: 5738 init1: 5738 opt: 5738 Z-score: 7070.4 bits: 1319.4 E(85289): 0 Smith-Waterman score: 5738; 99.0% identity (99.5% similar) in 883 aa overlap (1-883:1-883) 10 20 30 40 50 60 pF1KB4 MQKIMHISVLLSPVLWGLIFGVSSNSIQIGGLFPRGADQEYSAFRVGMVQFSTSEFRLTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MQKIMHISVLLSPVLWGLIFGVSSNSIQIGGLFPRGADQEYSAFRVGMVQFSTSEFRLTP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 HIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTDG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 THPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVTAINV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 THPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVTAINV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 GNINNDKKDEMYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYHYIIANL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GNINNDKKDEMYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYHYIIANL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 GFTDGDLLKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTTTIKYTSALT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GFTDGDLLKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTTTIKYTSALT 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 YDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEGLSGNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEGLSGNI 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB4 KFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTELPSGNDTSGLENKTVVVTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTELPSGNDTSGLENKTVVVTT 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB4 ILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKI 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB4 WNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLD 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB4 PLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQSSESTNEFGIFNSLWF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQSSESTNEFGIFNSLWF 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB4 SLGAFMRQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SLGAFMRQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDL 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB4 SKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGK 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB4 YAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLRTPVNLAVLKLSEQGVL ::::::::::::::::::::::::::::::::::::::::::::. ::::::::.:::.: NP_001 YAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLRNAVNLAVLKLNEQGLL 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB4 DKLKNKWWYDKGECGAKDSGSKEKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSR :::::::::::::::. . :::::::::::::::::::::::::::::::::::::::: NP_001 DKLKNKWWYDKGECGSGGGDSKEKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSR 790 800 810 820 830 840 850 860 870 880 pF1KB4 AEAKRMKVAKNAQNINPSSSQNSQNFATYKEGYNVYGIESVKI ::::::::::::::::::::::::::::::::::::::::::: NP_001 AEAKRMKVAKNAQNINPSSSQNSQNFATYKEGYNVYGIESVKI 850 860 870 880 >>NP_001077089 (OMIM: 138247) glutamate receptor 2 isofo (836 aa) initn: 5486 init1: 5486 opt: 5486 Z-score: 6760.0 bits: 1261.9 E(85289): 0 Smith-Waterman score: 5486; 100.0% identity (100.0% similar) in 836 aa overlap (48-883:1-836) 20 30 40 50 60 70 pF1KB4 LIFGVSSNSIQIGGLFPRGADQEYSAFRVGMVQFSTSEFRLTPHIDNLEVANSFAVTNAF :::::::::::::::::::::::::::::: NP_001 MVQFSTSEFRLTPHIDNLEVANSFAVTNAF 10 20 30 80 90 100 110 120 130 pF1KB4 CSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTDGTHPFVIQMRPDLKGALL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTDGTHPFVIQMRPDLKGALL 40 50 60 70 80 90 140 150 160 170 180 190 pF1KB4 SLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVTAINVGNINNDKKDEMYRSLFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVTAINVGNINNDKKDEMYRSLFQ 100 110 120 130 140 150 200 210 220 230 240 250 pF1KB4 DLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYHYIIANLGFTDGDLLKIQFGGANV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYHYIIANLGFTDGDLLKIQFGGANV 160 170 180 190 200 210 260 270 280 290 300 310 pF1KB4 SGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTTTIKYTSALTYDAVQVMTEAFRNLRKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTTTIKYTSALTYDAVQVMTEAFRNLRKQ 220 230 240 250 260 270 320 330 340 350 360 370 pF1KB4 RIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEGLSGNIKFDQNGKRINYTINIME :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEGLSGNIKFDQNGKRINYTINIME 280 290 300 310 320 330 380 390 400 410 420 430 pF1KB4 LKTNGPRKIGYWSEVDKMVVTLTELPSGNDTSGLENKTVVVTTILESPYVMMKKNHEMLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LKTNGPRKIGYWSEVDKMVVTLTELPSGNDTSGLENKTVVVTTILESPYVMMKKNHEMLE 340 350 360 370 380 390 440 450 460 470 480 490 pF1KB4 GNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAI 400 410 420 430 440 450 500 510 520 530 540 550 pF1KB4 APLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 APLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGV 460 470 480 490 500 510 560 570 580 590 600 610 pF1KB4 SVVLFLVSRFSPYEWHTEEFEDGRETQSSESTNEFGIFNSLWFSLGAFMRQGCDISPRSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SVVLFLVSRFSPYEWHTEEFEDGRETQSSESTNEFGIFNSLWFSLGAFMRQGCDISPRSL 520 530 540 550 560 570 620 630 640 650 660 670 pF1KB4 SGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLSKQTEIAYGTLDSGSTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLSKQTEIAYGTLDSGSTK 580 590 600 610 620 630 680 690 700 710 720 730 pF1KB4 EFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRK 640 650 660 670 680 690 740 750 760 770 780 790 pF1KB4 PCDTMKVGGNLDSKGYGIATPKGSSLRTPVNLAVLKLSEQGVLDKLKNKWWYDKGECGAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PCDTMKVGGNLDSKGYGIATPKGSSLRTPVNLAVLKLSEQGVLDKLKNKWWYDKGECGAK 700 710 720 730 740 750 800 810 820 830 840 850 pF1KB4 DSGSKEKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSRAEAKRMKVAKNAQNINP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DSGSKEKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSRAEAKRMKVAKNAQNINP 760 770 780 790 800 810 860 870 880 pF1KB4 SSSQNSQNFATYKEGYNVYGIESVKI :::::::::::::::::::::::::: NP_001 SSSQNSQNFATYKEGYNVYGIESVKI 820 830 >>XP_016863606 (OMIM: 138247) PREDICTED: glutamate recep (836 aa) initn: 5480 init1: 5480 opt: 5480 Z-score: 6752.6 bits: 1260.5 E(85289): 0 Smith-Waterman score: 5480; 99.9% identity (100.0% similar) in 836 aa overlap (48-883:1-836) 20 30 40 50 60 70 pF1KB4 LIFGVSSNSIQIGGLFPRGADQEYSAFRVGMVQFSTSEFRLTPHIDNLEVANSFAVTNAF :::::::::::::::::::::::::::::: XP_016 MVQFSTSEFRLTPHIDNLEVANSFAVTNAF 10 20 30 80 90 100 110 120 130 pF1KB4 CSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTDGTHPFVIQMRPDLKGALL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTDGTHPFVIQMRPDLKGALL 40 50 60 70 80 90 140 150 160 170 180 190 pF1KB4 SLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVTAINVGNINNDKKDEMYRSLFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVTAINVGNINNDKKDEMYRSLFQ 100 110 120 130 140 150 200 210 220 230 240 250 pF1KB4 DLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYHYIIANLGFTDGDLLKIQFGGANV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYHYIIANLGFTDGDLLKIQFGGANV 160 170 180 190 200 210 260 270 280 290 300 310 pF1KB4 SGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTTTIKYTSALTYDAVQVMTEAFRNLRKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTTTIKYTSALTYDAVQVMTEAFRNLRKQ 220 230 240 250 260 270 320 330 340 350 360 370 pF1KB4 RIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEGLSGNIKFDQNGKRINYTINIME :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEGLSGNIKFDQNGKRINYTINIME 280 290 300 310 320 330 380 390 400 410 420 430 pF1KB4 LKTNGPRKIGYWSEVDKMVVTLTELPSGNDTSGLENKTVVVTTILESPYVMMKKNHEMLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LKTNGPRKIGYWSEVDKMVVTLTELPSGNDTSGLENKTVVVTTILESPYVMMKKNHEMLE 340 350 360 370 380 390 440 450 460 470 480 490 pF1KB4 GNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAI 400 410 420 430 440 450 500 510 520 530 540 550 pF1KB4 APLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 APLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGV 460 470 480 490 500 510 560 570 580 590 600 610 pF1KB4 SVVLFLVSRFSPYEWHTEEFEDGRETQSSESTNEFGIFNSLWFSLGAFMRQGCDISPRSL :::::::::::::::::::::::::::::::::::::::::::::::::.:::::::::: XP_016 SVVLFLVSRFSPYEWHTEEFEDGRETQSSESTNEFGIFNSLWFSLGAFMQQGCDISPRSL 520 530 540 550 560 570 620 630 640 650 660 670 pF1KB4 SGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLSKQTEIAYGTLDSGSTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLSKQTEIAYGTLDSGSTK 580 590 600 610 620 630 680 690 700 710 720 730 pF1KB4 EFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRK 640 650 660 670 680 690 740 750 760 770 780 790 pF1KB4 PCDTMKVGGNLDSKGYGIATPKGSSLRTPVNLAVLKLSEQGVLDKLKNKWWYDKGECGAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PCDTMKVGGNLDSKGYGIATPKGSSLRTPVNLAVLKLSEQGVLDKLKNKWWYDKGECGAK 700 710 720 730 740 750 800 810 820 830 840 850 pF1KB4 DSGSKEKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSRAEAKRMKVAKNAQNINP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DSGSKEKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSRAEAKRMKVAKNAQNINP 760 770 780 790 800 810 860 870 880 pF1KB4 SSSQNSQNFATYKEGYNVYGIESVKI :::::::::::::::::::::::::: XP_016 SSSQNSQNFATYKEGYNVYGIESVKI 820 830 >>XP_016863605 (OMIM: 138247) PREDICTED: glutamate recep (836 aa) initn: 5480 init1: 5480 opt: 5480 Z-score: 6752.6 bits: 1260.5 E(85289): 0 Smith-Waterman score: 5480; 99.9% identity (100.0% similar) in 836 aa overlap (48-883:1-836) 20 30 40 50 60 70 pF1KB4 LIFGVSSNSIQIGGLFPRGADQEYSAFRVGMVQFSTSEFRLTPHIDNLEVANSFAVTNAF :::::::::::::::::::::::::::::: XP_016 MVQFSTSEFRLTPHIDNLEVANSFAVTNAF 10 20 30 80 90 100 110 120 130 pF1KB4 CSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTDGTHPFVIQMRPDLKGALL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTDGTHPFVIQMRPDLKGALL 40 50 60 70 80 90 140 150 160 170 180 190 pF1KB4 SLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVTAINVGNINNDKKDEMYRSLFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVTAINVGNINNDKKDEMYRSLFQ 100 110 120 130 140 150 200 210 220 230 240 250 pF1KB4 DLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYHYIIANLGFTDGDLLKIQFGGANV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYHYIIANLGFTDGDLLKIQFGGANV 160 170 180 190 200 210 260 270 280 290 300 310 pF1KB4 SGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTTTIKYTSALTYDAVQVMTEAFRNLRKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTTTIKYTSALTYDAVQVMTEAFRNLRKQ 220 230 240 250 260 270 320 330 340 350 360 370 pF1KB4 RIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEGLSGNIKFDQNGKRINYTINIME :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEGLSGNIKFDQNGKRINYTINIME 280 290 300 310 320 330 380 390 400 410 420 430 pF1KB4 LKTNGPRKIGYWSEVDKMVVTLTELPSGNDTSGLENKTVVVTTILESPYVMMKKNHEMLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LKTNGPRKIGYWSEVDKMVVTLTELPSGNDTSGLENKTVVVTTILESPYVMMKKNHEMLE 340 350 360 370 380 390 440 450 460 470 480 490 pF1KB4 GNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAI 400 410 420 430 440 450 500 510 520 530 540 550 pF1KB4 APLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 APLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGV 460 470 480 490 500 510 560 570 580 590 600 610 pF1KB4 SVVLFLVSRFSPYEWHTEEFEDGRETQSSESTNEFGIFNSLWFSLGAFMRQGCDISPRSL :::::::::::::::::::::::::::::::::::::::::::::::::.:::::::::: XP_016 SVVLFLVSRFSPYEWHTEEFEDGRETQSSESTNEFGIFNSLWFSLGAFMQQGCDISPRSL 520 530 540 550 560 570 620 630 640 650 660 670 pF1KB4 SGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLSKQTEIAYGTLDSGSTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLSKQTEIAYGTLDSGSTK 580 590 600 610 620 630 680 690 700 710 720 730 pF1KB4 EFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRK 640 650 660 670 680 690 740 750 760 770 780 790 pF1KB4 PCDTMKVGGNLDSKGYGIATPKGSSLRTPVNLAVLKLSEQGVLDKLKNKWWYDKGECGAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PCDTMKVGGNLDSKGYGIATPKGSSLRTPVNLAVLKLSEQGVLDKLKNKWWYDKGECGAK 700 710 720 730 740 750 800 810 820 830 840 850 pF1KB4 DSGSKEKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSRAEAKRMKVAKNAQNINP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DSGSKEKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSRAEAKRMKVAKNAQNINP 760 770 780 790 800 810 860 870 880 pF1KB4 SSSQNSQNFATYKEGYNVYGIESVKI :::::::::::::::::::::::::: XP_016 SSSQNSQNFATYKEGYNVYGIESVKI 820 830 >>XP_016863603 (OMIM: 138247) PREDICTED: glutamate recep (836 aa) initn: 5421 init1: 5421 opt: 5421 Z-score: 6679.8 bits: 1247.1 E(85289): 0 Smith-Waterman score: 5421; 98.8% identity (99.5% similar) in 836 aa overlap (48-883:1-836) 20 30 40 50 60 70 pF1KB4 LIFGVSSNSIQIGGLFPRGADQEYSAFRVGMVQFSTSEFRLTPHIDNLEVANSFAVTNAF :::::::::::::::::::::::::::::: XP_016 MVQFSTSEFRLTPHIDNLEVANSFAVTNAF 10 20 30 80 90 100 110 120 130 pF1KB4 CSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTDGTHPFVIQMRPDLKGALL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTDGTHPFVIQMRPDLKGALL 40 50 60 70 80 90 140 150 160 170 180 190 pF1KB4 SLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVTAINVGNINNDKKDEMYRSLFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVTAINVGNINNDKKDEMYRSLFQ 100 110 120 130 140 150 200 210 220 230 240 250 pF1KB4 DLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYHYIIANLGFTDGDLLKIQFGGANV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYHYIIANLGFTDGDLLKIQFGGANV 160 170 180 190 200 210 260 270 280 290 300 310 pF1KB4 SGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTTTIKYTSALTYDAVQVMTEAFRNLRKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTTTIKYTSALTYDAVQVMTEAFRNLRKQ 220 230 240 250 260 270 320 330 340 350 360 370 pF1KB4 RIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEGLSGNIKFDQNGKRINYTINIME :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEGLSGNIKFDQNGKRINYTINIME 280 290 300 310 320 330 380 390 400 410 420 430 pF1KB4 LKTNGPRKIGYWSEVDKMVVTLTELPSGNDTSGLENKTVVVTTILESPYVMMKKNHEMLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LKTNGPRKIGYWSEVDKMVVTLTELPSGNDTSGLENKTVVVTTILESPYVMMKKNHEMLE 340 350 360 370 380 390 440 450 460 470 480 490 pF1KB4 GNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAI 400 410 420 430 440 450 500 510 520 530 540 550 pF1KB4 APLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 APLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGV 460 470 480 490 500 510 560 570 580 590 600 610 pF1KB4 SVVLFLVSRFSPYEWHTEEFEDGRETQSSESTNEFGIFNSLWFSLGAFMRQGCDISPRSL :::::::::::::::::::::::::::::::::::::::::::::::::.:::::::::: XP_016 SVVLFLVSRFSPYEWHTEEFEDGRETQSSESTNEFGIFNSLWFSLGAFMQQGCDISPRSL 520 530 540 550 560 570 620 630 640 650 660 670 pF1KB4 SGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLSKQTEIAYGTLDSGSTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLSKQTEIAYGTLDSGSTK 580 590 600 610 620 630 680 690 700 710 720 730 pF1KB4 EFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRK 640 650 660 670 680 690 740 750 760 770 780 790 pF1KB4 PCDTMKVGGNLDSKGYGIATPKGSSLRTPVNLAVLKLSEQGVLDKLKNKWWYDKGECGAK :::::::::::::::::::::::::::. ::::::::.:::.::::::::::::::::. XP_016 PCDTMKVGGNLDSKGYGIATPKGSSLRNAVNLAVLKLNEQGLLDKLKNKWWYDKGECGSG 700 710 720 730 740 750 800 810 820 830 840 850 pF1KB4 DSGSKEKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSRAEAKRMKVAKNAQNINP . ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GGDSKEKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSRAEAKRMKVAKNAQNINP 760 770 780 790 800 810 860 870 880 pF1KB4 SSSQNSQNFATYKEGYNVYGIESVKI :::::::::::::::::::::::::: XP_016 SSSQNSQNFATYKEGYNVYGIESVKI 820 830 >>XP_016863602 (OMIM: 138247) PREDICTED: glutamate recep (836 aa) initn: 5421 init1: 5421 opt: 5421 Z-score: 6679.8 bits: 1247.1 E(85289): 0 Smith-Waterman score: 5421; 98.8% identity (99.5% similar) in 836 aa overlap (48-883:1-836) 20 30 40 50 60 70 pF1KB4 LIFGVSSNSIQIGGLFPRGADQEYSAFRVGMVQFSTSEFRLTPHIDNLEVANSFAVTNAF :::::::::::::::::::::::::::::: XP_016 MVQFSTSEFRLTPHIDNLEVANSFAVTNAF 10 20 30 80 90 100 110 120 130 pF1KB4 CSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTDGTHPFVIQMRPDLKGALL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTDGTHPFVIQMRPDLKGALL 40 50 60 70 80 90 140 150 160 170 180 190 pF1KB4 SLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVTAINVGNINNDKKDEMYRSLFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVTAINVGNINNDKKDEMYRSLFQ 100 110 120 130 140 150 200 210 220 230 240 250 pF1KB4 DLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYHYIIANLGFTDGDLLKIQFGGANV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYHYIIANLGFTDGDLLKIQFGGANV 160 170 180 190 200 210 260 270 280 290 300 310 pF1KB4 SGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTTTIKYTSALTYDAVQVMTEAFRNLRKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTTTIKYTSALTYDAVQVMTEAFRNLRKQ 220 230 240 250 260 270 320 330 340 350 360 370 pF1KB4 RIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEGLSGNIKFDQNGKRINYTINIME :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEGLSGNIKFDQNGKRINYTINIME 280 290 300 310 320 330 380 390 400 410 420 430 pF1KB4 LKTNGPRKIGYWSEVDKMVVTLTELPSGNDTSGLENKTVVVTTILESPYVMMKKNHEMLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LKTNGPRKIGYWSEVDKMVVTLTELPSGNDTSGLENKTVVVTTILESPYVMMKKNHEMLE 340 350 360 370 380 390 440 450 460 470 480 490 pF1KB4 GNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAI 400 410 420 430 440 450 500 510 520 530 540 550 pF1KB4 APLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 APLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGV 460 470 480 490 500 510 560 570 580 590 600 610 pF1KB4 SVVLFLVSRFSPYEWHTEEFEDGRETQSSESTNEFGIFNSLWFSLGAFMRQGCDISPRSL :::::::::::::::::::::::::::::::::::::::::::::::::.:::::::::: XP_016 SVVLFLVSRFSPYEWHTEEFEDGRETQSSESTNEFGIFNSLWFSLGAFMQQGCDISPRSL 520 530 540 550 560 570 620 630 640 650 660 670 pF1KB4 SGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLSKQTEIAYGTLDSGSTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLSKQTEIAYGTLDSGSTK 580 590 600 610 620 630 680 690 700 710 720 730 pF1KB4 EFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRK 640 650 660 670 680 690 740 750 760 770 780 790 pF1KB4 PCDTMKVGGNLDSKGYGIATPKGSSLRTPVNLAVLKLSEQGVLDKLKNKWWYDKGECGAK :::::::::::::::::::::::::::. ::::::::.:::.::::::::::::::::. XP_016 PCDTMKVGGNLDSKGYGIATPKGSSLRNAVNLAVLKLNEQGLLDKLKNKWWYDKGECGSG 700 710 720 730 740 750 800 810 820 830 840 850 pF1KB4 DSGSKEKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSRAEAKRMKVAKNAQNINP . ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GGDSKEKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSRAEAKRMKVAKNAQNINP 760 770 780 790 800 810 860 870 880 pF1KB4 SSSQNSQNFATYKEGYNVYGIESVKI :::::::::::::::::::::::::: XP_016 SSSQNSQNFATYKEGYNVYGIESVKI 820 830 >>XP_016863604 (OMIM: 138247) PREDICTED: glutamate recep (836 aa) initn: 5421 init1: 5421 opt: 5421 Z-score: 6679.8 bits: 1247.1 E(85289): 0 Smith-Waterman score: 5421; 98.8% identity (99.5% similar) in 836 aa overlap (48-883:1-836) 20 30 40 50 60 70 pF1KB4 LIFGVSSNSIQIGGLFPRGADQEYSAFRVGMVQFSTSEFRLTPHIDNLEVANSFAVTNAF :::::::::::::::::::::::::::::: XP_016 MVQFSTSEFRLTPHIDNLEVANSFAVTNAF 10 20 30 80 90 100 110 120 130 pF1KB4 CSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTDGTHPFVIQMRPDLKGALL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTDGTHPFVIQMRPDLKGALL 40 50 60 70 80 90 140 150 160 170 180 190 pF1KB4 SLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVTAINVGNINNDKKDEMYRSLFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVTAINVGNINNDKKDEMYRSLFQ 100 110 120 130 140 150 200 210 220 230 240 250 pF1KB4 DLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYHYIIANLGFTDGDLLKIQFGGANV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYHYIIANLGFTDGDLLKIQFGGANV 160 170 180 190 200 210 260 270 280 290 300 310 pF1KB4 SGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTTTIKYTSALTYDAVQVMTEAFRNLRKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTTTIKYTSALTYDAVQVMTEAFRNLRKQ 220 230 240 250 260 270 320 330 340 350 360 370 pF1KB4 RIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEGLSGNIKFDQNGKRINYTINIME :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEGLSGNIKFDQNGKRINYTINIME 280 290 300 310 320 330 380 390 400 410 420 430 pF1KB4 LKTNGPRKIGYWSEVDKMVVTLTELPSGNDTSGLENKTVVVTTILESPYVMMKKNHEMLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LKTNGPRKIGYWSEVDKMVVTLTELPSGNDTSGLENKTVVVTTILESPYVMMKKNHEMLE 340 350 360 370 380 390 440 450 460 470 480 490 pF1KB4 GNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAI 400 410 420 430 440 450 500 510 520 530 540 550 pF1KB4 APLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 APLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGV 460 470 480 490 500 510 560 570 580 590 600 610 pF1KB4 SVVLFLVSRFSPYEWHTEEFEDGRETQSSESTNEFGIFNSLWFSLGAFMRQGCDISPRSL :::::::::::::::::::::::::::::::::::::::::::::::::.:::::::::: XP_016 SVVLFLVSRFSPYEWHTEEFEDGRETQSSESTNEFGIFNSLWFSLGAFMQQGCDISPRSL 520 530 540 550 560 570 620 630 640 650 660 670 pF1KB4 SGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLSKQTEIAYGTLDSGSTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLSKQTEIAYGTLDSGSTK 580 590 600 610 620 630 680 690 700 710 720 730 pF1KB4 EFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRK 640 650 660 670 680 690 740 750 760 770 780 790 pF1KB4 PCDTMKVGGNLDSKGYGIATPKGSSLRTPVNLAVLKLSEQGVLDKLKNKWWYDKGECGAK :::::::::::::::::::::::::::. ::::::::.:::.::::::::::::::::. XP_016 PCDTMKVGGNLDSKGYGIATPKGSSLRNAVNLAVLKLNEQGLLDKLKNKWWYDKGECGSG 700 710 720 730 740 750 800 810 820 830 840 850 pF1KB4 DSGSKEKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSRAEAKRMKVAKNAQNINP . ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GGDSKEKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSRAEAKRMKVAKNAQNINP 760 770 780 790 800 810 860 870 880 pF1KB4 SSSQNSQNFATYKEGYNVYGIESVKI :::::::::::::::::::::::::: XP_016 SSSQNSQNFATYKEGYNVYGIESVKI 820 830 >>XP_011541077 (OMIM: 138246) PREDICTED: glutamate recep (884 aa) initn: 4028 init1: 3425 opt: 4537 Z-score: 5589.4 bits: 1045.4 E(85289): 0 Smith-Waterman score: 4537; 74.4% identity (92.5% similar) in 890 aa overlap (1-883:1-884) 10 20 30 40 50 pF1KB4 MQKIMHISVLLSPVLWGLIFGVSSNSIQIGGLFPRGADQEYSAFRVGMVQFSTSE----- :. : . ::: .::: .:. .:.:::::: :..::::.:::... .:: XP_011 MRIISRQIVLLFSGFWGLAMGAFPSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEA 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB4 -FRLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITP : :.::.::.:.:::::::::::::.::::.::::.:::.::.:.::::..::.:.::: XP_011 PFNLVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITP 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB4 SFPTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQ ::::.: ::.:.::.:.::::::...:.:. :..:::.::: : :::....:... :. XP_011 SFPTEGESQFVLQLRPSLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWH 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB4 VTAINVGNINNDKKDEMYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYH :.:: : :.: : ::.:...:. ..:.. ..::: .....:..:....:::::::: XP_011 VSAICVENFN----DVSYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVKGYH 190 200 210 220 230 240 250 260 270 280 290 pF1KB4 YIIANLGFTDGDLLKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTTTIK :::::::: : .: .. :::::.:::.::.. .: :...::. :...::::..: : XP_011 YIIANLGFKDISLERFIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSETPP-K 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB4 YTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVE ::::::::.: ::.:.::.::.:.:.:::::::::::::::.:::::...::.::::... XP_011 YTSALTYDGVLVMAETFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQ 300 310 320 330 340 350 360 370 380 390 400 410 pF1KB4 GLSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTELPS-GNDTSGLEN ::.::..::. :.:.:::....:::..::::.:::...::.:. . ..:. ::::...:: XP_011 GLTGNVQFDHYGRRVNYTMDVFELKSTGPRKVGYWNDMDKLVL-IQDVPTLGNDTAAIEN 360 370 380 390 400 410 420 430 440 450 460 470 pF1KB4 KTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGA .:::::::.::::::.::::::.:::..:::::::::.::::: :.:::..:: :::::: XP_011 RTVVVTTIMESPYVMYKKNHEMFEGNDKYEGYCVDLASEIAKHIGIKYKIAIVPDGKYGA 420 430 440 450 460 470 480 490 500 510 520 530 pF1KB4 RDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKP ::::::::::::::::::::.::::::::::::::::::::::::::::::::::::::: XP_011 RDADTKIWNGMVGELVYGKAEIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKP 480 490 500 510 520 530 540 550 560 570 580 590 pF1KB4 GVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQSSESTNEFG ::::::::::::::::::::::::::::::::::::::::::: :::.: :.. :::: XP_011 GVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEPEDGKEGPSDQPPNEFG 540 550 560 570 580 590 600 610 620 630 640 650 pF1KB4 IFNSLWFSLGAFMRQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSP :::::::::::::.:::::::::::::::::::::::::::::::::::::::::::::: XP_011 IFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSP 600 610 620 630 640 650 660 670 680 690 700 710 pF1KB4 IESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVAR :::::::.::::::::::::::::::::::::::..::::::::::::::.::::::::: XP_011 IESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWTYMRSAEPSVFTRTTAEGVAR 660 670 680 690 700 710 720 730 740 750 760 770 pF1KB4 VRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLRTPVNLAVLK :::::::.:.:::::::::::::::::::::::::::::::.:::::::::::::::::: XP_011 VRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSSLRTPVNLAVLK 720 730 740 750 760 770 780 790 800 810 820 830 pF1KB4 LSEQGVLDKLKNKWWYDKGECGAKDSGSKEKTSALSLSNVAGVFYILVGGLGLAMLVALI ::: :::::::::::::::::: ::::::.:::::::::::::::::::::::::::::: XP_011 LSEAGVLDKLKNKWWYDKGECGPKDSGSKDKTSALSLSNVAGVFYILVGGLGLAMLVALI 780 790 800 810 820 830 840 850 860 870 880 pF1KB4 EFCYKSRAEAKRMKVAKNAQNINPSSSQNSQNFATYKEGYNVYGIESVKI :::::::::::::::::.::..::.::::.::.:::.::::::: ::.:: XP_011 EFCYKSRAEAKRMKVAKSAQTFNPTSSQNTQNLATYREGYNVYGTESIKI 840 850 860 870 880 >>NP_001070711 (OMIM: 138246) glutamate receptor 4 isofo (884 aa) initn: 3973 init1: 3370 opt: 4482 Z-score: 5521.6 bits: 1032.8 E(85289): 0 Smith-Waterman score: 4482; 73.5% identity (92.1% similar) in 890 aa overlap (1-883:1-884) 10 20 30 40 50 pF1KB4 MQKIMHISVLLSPVLWGLIFGVSSNSIQIGGLFPRGADQEYSAFRVGMVQFSTSE----- :. : . ::: .::: .:. .:.:::::: :..::::.:::... .:: NP_001 MRIISRQIVLLFSGFWGLAMGAFPSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEA 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB4 -FRLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITP : :.::.::.:.:::::::::::::.::::.::::.:::.::.:.::::..::.:.::: NP_001 PFNLVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITP 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB4 SFPTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQ ::::.: ::.:.::.:.::::::...:.:. :..:::.::: : :::....:... :. NP_001 SFPTEGESQFVLQLRPSLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWH 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB4 VTAINVGNINNDKKDEMYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYH :.:: : :.: : ::.:...:. ..:.. ..::: .....:..:....:::::::: NP_001 VSAICVENFN----DVSYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVKGYH 190 200 210 220 230 240 250 260 270 280 290 pF1KB4 YIIANLGFTDGDLLKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTTTIK :::::::: : .: .. :::::.:::.::.. .: :...::. :...::::..: : NP_001 YIIANLGFKDISLERFIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSETPP-K 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB4 YTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVE ::::::::.: ::.:.::.::.:.:.:::::::::::::::.:::::...::.::::... NP_001 YTSALTYDGVLVMAETFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQ 300 310 320 330 340 350 360 370 380 390 400 410 pF1KB4 GLSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTELPS-GNDTSGLEN ::.::..::. :.:.:::....:::..::::.:::...::.:. . ..:. ::::...:: NP_001 GLTGNVQFDHYGRRVNYTMDVFELKSTGPRKVGYWNDMDKLVL-IQDVPTLGNDTAAIEN 360 370 380 390 400 410 420 430 440 450 460 470 pF1KB4 KTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGA .:::::::.::::::.::::::.:::..:::::::::.::::: :.:::..:: :::::: NP_001 RTVVVTTIMESPYVMYKKNHEMFEGNDKYEGYCVDLASEIAKHIGIKYKIAIVPDGKYGA 420 430 440 450 460 470 480 490 500 510 520 530 pF1KB4 RDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKP ::::::::::::::::::::.::::::::::::::::::::::::::::::::::::::: NP_001 RDADTKIWNGMVGELVYGKAEIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKP 480 490 500 510 520 530 540 550 560 570 580 590 pF1KB4 GVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQSSESTNEFG ::::::::::::::::::::::::::::::::::::::::::: :::.: :.. :::: NP_001 GVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEPEDGKEGPSDQPPNEFG 540 550 560 570 580 590 600 610 620 630 640 650 pF1KB4 IFNSLWFSLGAFMRQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSP :::::::::::::.:::::::::::::::::::::::::::::::::::::::::::::: NP_001 IFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSP 600 610 620 630 640 650 660 670 680 690 700 710 pF1KB4 IESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVAR :::::::.::::::::::::::::::::::::::..::::::::::::::.::::::::: NP_001 IESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWTYMRSAEPSVFTRTTAEGVAR 660 670 680 690 700 710 720 730 740 750 760 770 pF1KB4 VRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLRTPVNLAVLK :::::::.:.:::::::::::::::::::::::::::::::.:::::::: . ::::::: NP_001 VRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSSLGNAVNLAVLK 720 730 740 750 760 770 780 790 800 810 820 830 pF1KB4 LSEQGVLDKLKNKWWYDKGECGAKDSGSKEKTSALSLSNVAGVFYILVGGLGLAMLVALI :.:::.::::::::::::::::. . ::.:::::::::::::::::::::::::::::: NP_001 LNEQGLLDKLKNKWWYDKGECGSGGGDSKDKTSALSLSNVAGVFYILVGGLGLAMLVALI 780 790 800 810 820 830 840 850 860 870 880 pF1KB4 EFCYKSRAEAKRMKVAKNAQNINPSSSQNSQNFATYKEGYNVYGIESVKI :::::::::::::::::.::..::.::::.::.:::.::::::: ::.:: NP_001 EFCYKSRAEAKRMKVAKSAQTFNPTSSQNTQNLATYREGYNVYGTESIKI 840 850 860 870 880 883 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 15:23:29 2016 done: Thu Nov 3 15:23:31 2016 Total Scan time: 11.360 Total Display time: 0.360 Function used was FASTA [36.3.4 Apr, 2011]