FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB4702, 574 aa 1>>>pF1KB4702 574 - 574 aa - 574 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.8533+/-0.00061; mu= 15.1746+/- 0.038 mean_var=316.7580+/-74.135, 0's: 0 Z-trim(112.6): 186 B-trim: 647 in 1/53 Lambda= 0.072063 statistics sampled from 21451 (21637) to 21451 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.6), E-opt: 0.2 (0.254), width: 16 Scan time: 8.300 The best scores are: opt bits E(85289) NP_001647 (OMIM: 601747) E3 ubiquitin-protein liga ( 574) 3872 417.6 5.5e-116 XP_016864933 (OMIM: 601747) PREDICTED: E3 ubiquiti ( 569) 3714 401.2 4.8e-111 NP_150230 (OMIM: 601747) E3 ubiquitin-protein liga ( 569) 3714 401.2 4.8e-111 NP_150231 (OMIM: 601747) E3 ubiquitin-protein liga ( 546) 3633 392.7 1.6e-108 XP_005248554 (OMIM: 601747) PREDICTED: E3 ubiquiti ( 398) 2666 291.9 2.6e-78 NP_001019399 (OMIM: 103180) ADP-ribosylation facto ( 181) 699 86.9 6.3e-17 NP_001019398 (OMIM: 103180) ADP-ribosylation facto ( 181) 699 86.9 6.3e-17 NP_001649 (OMIM: 103180) ADP-ribosylation factor 1 ( 181) 699 86.9 6.3e-17 NP_001019397 (OMIM: 103180) ADP-ribosylation facto ( 181) 699 86.9 6.3e-17 NP_001650 (OMIM: 103190) ADP-ribosylation factor 3 ( 181) 697 86.7 7.3e-17 XP_005268913 (OMIM: 103190) PREDICTED: ADP-ribosyl ( 181) 697 86.7 7.3e-17 NP_001653 (OMIM: 103188) ADP-ribosylation factor 5 ( 180) 671 84.0 4.7e-16 NP_001651 (OMIM: 601177) ADP-ribosylation factor 4 ( 180) 664 83.2 7.8e-16 NP_001654 (OMIM: 600464) ADP-ribosylation factor 6 ( 175) 632 79.9 7.7e-15 NP_001168 (OMIM: 603425) ADP-ribosylation factor-l ( 181) 561 72.5 1.3e-12 XP_006719454 (OMIM: 103190) PREDICTED: ADP-ribosyl ( 137) 528 68.9 1.2e-11 XP_016856722 (OMIM: 103180) PREDICTED: ADP-ribosyl ( 212) 526 69.0 1.8e-11 NP_004302 (OMIM: 604695) ADP-ribosylation factor-l ( 182) 509 67.1 5.6e-11 XP_016871749 (OMIM: 604695) PREDICTED: ADP-ribosyl ( 182) 509 67.1 5.6e-11 NP_036229 (OMIM: 608960) ADP-ribosylation factor-l ( 179) 503 66.5 8.5e-11 NP_001658 (OMIM: 601175) ADP-ribosylation factor-l ( 184) 495 65.7 1.5e-10 NP_079323 (OMIM: 614439) ADP-ribosylation factor-l ( 192) 495 65.7 1.6e-10 NP_848930 (OMIM: 608909) ADP-ribosylation factor-l ( 179) 484 64.5 3.3e-10 NP_001652 (OMIM: 600732) ADP-ribosylation factor-l ( 201) 453 61.4 3.3e-09 XP_011523084 (OMIM: 600732) PREDICTED: ADP-ribosyl ( 201) 453 61.4 3.3e-09 NP_005728 (OMIM: 604787) ADP-ribosylation factor-l ( 192) 452 61.2 3.5e-09 NP_001269360 (OMIM: 604787) ADP-ribosylation facto ( 201) 452 61.3 3.6e-09 NP_001182325 (OMIM: 604786) ADP-ribosylation facto ( 200) 442 60.2 7.3e-09 NP_997625 (OMIM: 604786) ADP-ribosylation factor-l ( 200) 442 60.2 7.3e-09 NP_001032241 (OMIM: 604786) ADP-ribosylation facto ( 200) 442 60.2 7.3e-09 NP_005729 (OMIM: 604786) ADP-ribosylation factor-l ( 200) 442 60.2 7.3e-09 NP_001287997 (OMIM: 603425) ADP-ribosylation facto ( 135) 435 59.2 9.9e-09 NP_816931 (OMIM: 209900,268000,600151,608845,61357 ( 186) 427 58.6 2.1e-08 NP_115522 (OMIM: 209900,268000,600151,608845,61357 ( 186) 427 58.6 2.1e-08 XP_016862800 (OMIM: 209900,268000,600151,608845,61 ( 186) 427 58.6 2.1e-08 NP_001265222 (OMIM: 209900,268000,600151,608845,61 ( 186) 427 58.6 2.1e-08 NP_001310442 (OMIM: 209900,268000,600151,608845,61 ( 193) 425 58.4 2.4e-08 NP_817114 (OMIM: 608960) ADP-ribosylation factor-l ( 142) 420 57.7 3e-08 NP_001032251 (OMIM: 608960) ADP-ribosylation facto ( 142) 420 57.7 3e-08 NP_612459 (OMIM: 609351) ADP-ribosylation factor-l ( 196) 412 57.1 6.3e-08 XP_005266310 (OMIM: 609351) PREDICTED: ADP-ribosyl ( 196) 412 57.1 6.3e-08 XP_005252458 (OMIM: 608909) PREDICTED: ADP-ribosyl ( 142) 406 56.2 8.2e-08 NP_001310443 (OMIM: 209900,268000,600151,608845,61 ( 159) 354 50.9 3.7e-06 XP_016862801 (OMIM: 209900,268000,600151,608845,61 ( 159) 354 50.9 3.7e-06 NP_001254477 (OMIM: 604699) ADP-ribosylation facto ( 201) 339 49.5 1.2e-05 NP_003215 (OMIM: 604699) ADP-ribosylation factor-r ( 201) 339 49.5 1.2e-05 NP_001254476 (OMIM: 604699) ADP-ribosylation facto ( 201) 339 49.5 1.2e-05 XP_011526784 (OMIM: 604699) PREDICTED: ADP-ribosyl ( 201) 339 49.5 1.2e-05 XP_011526785 (OMIM: 604699) PREDICTED: ADP-ribosyl ( 201) 339 49.5 1.2e-05 XP_016883065 (OMIM: 604699) PREDICTED: ADP-ribosyl ( 201) 339 49.5 1.2e-05 >>NP_001647 (OMIM: 601747) E3 ubiquitin-protein ligase T (574 aa) initn: 3872 init1: 3872 opt: 3872 Z-score: 2203.3 bits: 417.6 E(85289): 5.5e-116 Smith-Waterman score: 3872; 100.0% identity (100.0% similar) in 574 aa overlap (1-574:1-574) 10 20 30 40 50 60 pF1KB4 MATLVVNKLGAGVDSGRQGSRGTAVVKVLECGVCEDVFSLQGDKVPRLLLCGHTVCHDCL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MATLVVNKLGAGVDSGRQGSRGTAVVKVLECGVCEDVFSLQGDKVPRLLLCGHTVCHDCL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 TRLPLHGRAIRCPFDRQVTDLGDSGVWGLKKNFALLELLERLQNGPIGQYGAAEESIGIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TRLPLHGRAIRCPFDRQVTDLGDSGVWGLKKNFALLELLERLQNGPIGQYGAAEESIGIS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 GESIIRCDEDEAHLASVYCTVCATHLCSECSQVTHSTKTLAKHRRVPLADKPHEKTMCSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GESIIRCDEDEAHLASVYCTVCATHLCSECSQVTHSTKTLAKHRRVPLADKPHEKTMCSQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 HQVHAIEFVCLEEGCQTSPLMCCVCKEYGKHQGHKHSVLEPEANQIRASILDMAHCIRTF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HQVHAIEFVCLEEGCQTSPLMCCVCKEYGKHQGHKHSVLEPEANQIRASILDMAHCIRTF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 TEEISDYSRKLVGIVQHIEGGEQIVEDGIGMAHTEHVPGTAENARSCIRAYFYDLHETLC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TEEISDYSRKLVGIVQHIEGGEQIVEDGIGMAHTEHVPGTAENARSCIRAYFYDLHETLC 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 RQEEMALSVVDAHVREKLIWLRQQQEDMTILLSEVSAACLHCEKTLQQDDCRVVLAKQEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RQEEMALSVVDAHVREKLIWLRQQQEDMTILLSEVSAACLHCEKTLQQDDCRVVLAKQEI 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB4 TRLLETLQKQQQQFTEVADHIQLDASIPVTFTKDNRVHIGPKMEIRVVTLGLDGAGKTTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TRLLETLQKQQQQFTEVADHIQLDASIPVTFTKDNRVHIGPKMEIRVVTLGLDGAGKTTI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB4 LFKLKQDEFMQPIPTIGFNVETVEYKNLKFTIWDVGGKHKLRPLWKHYYLNTQAVVFVVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LFKLKQDEFMQPIPTIGFNVETVEYKNLKFTIWDVGGKHKLRPLWKHYYLNTQAVVFVVD 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB4 SSHRDRISEAHSELAKLLTEKELRDALLLIFANKQDVAGALSVEEITELLSLHKLCCGRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSHRDRISEAHSELAKLLTEKELRDALLLIFANKQDVAGALSVEEITELLSLHKLCCGRS 490 500 510 520 530 540 550 560 570 pF1KB4 WYIQGCDARSGMGLYEGLDWLSRQLVAAGVLDVA :::::::::::::::::::::::::::::::::: NP_001 WYIQGCDARSGMGLYEGLDWLSRQLVAAGVLDVA 550 560 570 >>XP_016864933 (OMIM: 601747) PREDICTED: E3 ubiquitin-pr (569 aa) initn: 3714 init1: 3714 opt: 3714 Z-score: 2114.5 bits: 401.2 E(85289): 4.8e-111 Smith-Waterman score: 3714; 100.0% identity (100.0% similar) in 550 aa overlap (1-550:1-550) 10 20 30 40 50 60 pF1KB4 MATLVVNKLGAGVDSGRQGSRGTAVVKVLECGVCEDVFSLQGDKVPRLLLCGHTVCHDCL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MATLVVNKLGAGVDSGRQGSRGTAVVKVLECGVCEDVFSLQGDKVPRLLLCGHTVCHDCL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 TRLPLHGRAIRCPFDRQVTDLGDSGVWGLKKNFALLELLERLQNGPIGQYGAAEESIGIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TRLPLHGRAIRCPFDRQVTDLGDSGVWGLKKNFALLELLERLQNGPIGQYGAAEESIGIS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 GESIIRCDEDEAHLASVYCTVCATHLCSECSQVTHSTKTLAKHRRVPLADKPHEKTMCSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GESIIRCDEDEAHLASVYCTVCATHLCSECSQVTHSTKTLAKHRRVPLADKPHEKTMCSQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 HQVHAIEFVCLEEGCQTSPLMCCVCKEYGKHQGHKHSVLEPEANQIRASILDMAHCIRTF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HQVHAIEFVCLEEGCQTSPLMCCVCKEYGKHQGHKHSVLEPEANQIRASILDMAHCIRTF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 TEEISDYSRKLVGIVQHIEGGEQIVEDGIGMAHTEHVPGTAENARSCIRAYFYDLHETLC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TEEISDYSRKLVGIVQHIEGGEQIVEDGIGMAHTEHVPGTAENARSCIRAYFYDLHETLC 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 RQEEMALSVVDAHVREKLIWLRQQQEDMTILLSEVSAACLHCEKTLQQDDCRVVLAKQEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RQEEMALSVVDAHVREKLIWLRQQQEDMTILLSEVSAACLHCEKTLQQDDCRVVLAKQEI 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB4 TRLLETLQKQQQQFTEVADHIQLDASIPVTFTKDNRVHIGPKMEIRVVTLGLDGAGKTTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TRLLETLQKQQQQFTEVADHIQLDASIPVTFTKDNRVHIGPKMEIRVVTLGLDGAGKTTI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB4 LFKLKQDEFMQPIPTIGFNVETVEYKNLKFTIWDVGGKHKLRPLWKHYYLNTQAVVFVVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LFKLKQDEFMQPIPTIGFNVETVEYKNLKFTIWDVGGKHKLRPLWKHYYLNTQAVVFVVD 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB4 SSHRDRISEAHSELAKLLTEKELRDALLLIFANKQDVAGALSVEEITELLSLHKLCCGRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSHRDRISEAHSELAKLLTEKELRDALLLIFANKQDVAGALSVEEITELLSLHKLCCGRS 490 500 510 520 530 540 550 560 570 pF1KB4 WYIQGCDARSGMGLYEGLDWLSRQLVAAGVLDVA :::::::::: XP_016 WYIQGCDARSVFQIICDQYTGKEVVTEKG 550 560 >>NP_150230 (OMIM: 601747) E3 ubiquitin-protein ligase T (569 aa) initn: 3714 init1: 3714 opt: 3714 Z-score: 2114.5 bits: 401.2 E(85289): 4.8e-111 Smith-Waterman score: 3714; 100.0% identity (100.0% similar) in 550 aa overlap (1-550:1-550) 10 20 30 40 50 60 pF1KB4 MATLVVNKLGAGVDSGRQGSRGTAVVKVLECGVCEDVFSLQGDKVPRLLLCGHTVCHDCL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_150 MATLVVNKLGAGVDSGRQGSRGTAVVKVLECGVCEDVFSLQGDKVPRLLLCGHTVCHDCL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 TRLPLHGRAIRCPFDRQVTDLGDSGVWGLKKNFALLELLERLQNGPIGQYGAAEESIGIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_150 TRLPLHGRAIRCPFDRQVTDLGDSGVWGLKKNFALLELLERLQNGPIGQYGAAEESIGIS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 GESIIRCDEDEAHLASVYCTVCATHLCSECSQVTHSTKTLAKHRRVPLADKPHEKTMCSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_150 GESIIRCDEDEAHLASVYCTVCATHLCSECSQVTHSTKTLAKHRRVPLADKPHEKTMCSQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 HQVHAIEFVCLEEGCQTSPLMCCVCKEYGKHQGHKHSVLEPEANQIRASILDMAHCIRTF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_150 HQVHAIEFVCLEEGCQTSPLMCCVCKEYGKHQGHKHSVLEPEANQIRASILDMAHCIRTF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 TEEISDYSRKLVGIVQHIEGGEQIVEDGIGMAHTEHVPGTAENARSCIRAYFYDLHETLC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_150 TEEISDYSRKLVGIVQHIEGGEQIVEDGIGMAHTEHVPGTAENARSCIRAYFYDLHETLC 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 RQEEMALSVVDAHVREKLIWLRQQQEDMTILLSEVSAACLHCEKTLQQDDCRVVLAKQEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_150 RQEEMALSVVDAHVREKLIWLRQQQEDMTILLSEVSAACLHCEKTLQQDDCRVVLAKQEI 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB4 TRLLETLQKQQQQFTEVADHIQLDASIPVTFTKDNRVHIGPKMEIRVVTLGLDGAGKTTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_150 TRLLETLQKQQQQFTEVADHIQLDASIPVTFTKDNRVHIGPKMEIRVVTLGLDGAGKTTI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB4 LFKLKQDEFMQPIPTIGFNVETVEYKNLKFTIWDVGGKHKLRPLWKHYYLNTQAVVFVVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_150 LFKLKQDEFMQPIPTIGFNVETVEYKNLKFTIWDVGGKHKLRPLWKHYYLNTQAVVFVVD 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB4 SSHRDRISEAHSELAKLLTEKELRDALLLIFANKQDVAGALSVEEITELLSLHKLCCGRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_150 SSHRDRISEAHSELAKLLTEKELRDALLLIFANKQDVAGALSVEEITELLSLHKLCCGRS 490 500 510 520 530 540 550 560 570 pF1KB4 WYIQGCDARSGMGLYEGLDWLSRQLVAAGVLDVA :::::::::: NP_150 WYIQGCDARSVFQIICDQYTGKEVVTEKG 550 560 >>NP_150231 (OMIM: 601747) E3 ubiquitin-protein ligase T (546 aa) initn: 3633 init1: 3633 opt: 3633 Z-score: 2069.2 bits: 392.7 E(85289): 1.6e-108 Smith-Waterman score: 3633; 100.0% identity (100.0% similar) in 540 aa overlap (1-540:1-540) 10 20 30 40 50 60 pF1KB4 MATLVVNKLGAGVDSGRQGSRGTAVVKVLECGVCEDVFSLQGDKVPRLLLCGHTVCHDCL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_150 MATLVVNKLGAGVDSGRQGSRGTAVVKVLECGVCEDVFSLQGDKVPRLLLCGHTVCHDCL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 TRLPLHGRAIRCPFDRQVTDLGDSGVWGLKKNFALLELLERLQNGPIGQYGAAEESIGIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_150 TRLPLHGRAIRCPFDRQVTDLGDSGVWGLKKNFALLELLERLQNGPIGQYGAAEESIGIS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 GESIIRCDEDEAHLASVYCTVCATHLCSECSQVTHSTKTLAKHRRVPLADKPHEKTMCSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_150 GESIIRCDEDEAHLASVYCTVCATHLCSECSQVTHSTKTLAKHRRVPLADKPHEKTMCSQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 HQVHAIEFVCLEEGCQTSPLMCCVCKEYGKHQGHKHSVLEPEANQIRASILDMAHCIRTF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_150 HQVHAIEFVCLEEGCQTSPLMCCVCKEYGKHQGHKHSVLEPEANQIRASILDMAHCIRTF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 TEEISDYSRKLVGIVQHIEGGEQIVEDGIGMAHTEHVPGTAENARSCIRAYFYDLHETLC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_150 TEEISDYSRKLVGIVQHIEGGEQIVEDGIGMAHTEHVPGTAENARSCIRAYFYDLHETLC 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 RQEEMALSVVDAHVREKLIWLRQQQEDMTILLSEVSAACLHCEKTLQQDDCRVVLAKQEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_150 RQEEMALSVVDAHVREKLIWLRQQQEDMTILLSEVSAACLHCEKTLQQDDCRVVLAKQEI 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB4 TRLLETLQKQQQQFTEVADHIQLDASIPVTFTKDNRVHIGPKMEIRVVTLGLDGAGKTTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_150 TRLLETLQKQQQQFTEVADHIQLDASIPVTFTKDNRVHIGPKMEIRVVTLGLDGAGKTTI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB4 LFKLKQDEFMQPIPTIGFNVETVEYKNLKFTIWDVGGKHKLRPLWKHYYLNTQAVVFVVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_150 LFKLKQDEFMQPIPTIGFNVETVEYKNLKFTIWDVGGKHKLRPLWKHYYLNTQAVVFVVD 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB4 SSHRDRISEAHSELAKLLTEKELRDALLLIFANKQDVAGALSVEEITELLSLHKLCCGRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_150 SSHRDRISEAHSELAKLLTEKELRDALLLIFANKQDVAGALSVEEITELLSLHKLCCGRS 490 500 510 520 530 540 550 560 570 pF1KB4 WYIQGCDARSGMGLYEGLDWLSRQLVAAGVLDVA NP_150 CFSDNM >>XP_005248554 (OMIM: 601747) PREDICTED: E3 ubiquitin-pr (398 aa) initn: 2666 init1: 2666 opt: 2666 Z-score: 1527.1 bits: 291.9 E(85289): 2.6e-78 Smith-Waterman score: 2666; 100.0% identity (100.0% similar) in 398 aa overlap (177-574:1-398) 150 160 170 180 190 200 pF1KB4 CSECSQVTHSTKTLAKHRRVPLADKPHEKTMCSQHQVHAIEFVCLEEGCQTSPLMCCVCK :::::::::::::::::::::::::::::: XP_005 MCSQHQVHAIEFVCLEEGCQTSPLMCCVCK 10 20 30 210 220 230 240 250 260 pF1KB4 EYGKHQGHKHSVLEPEANQIRASILDMAHCIRTFTEEISDYSRKLVGIVQHIEGGEQIVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EYGKHQGHKHSVLEPEANQIRASILDMAHCIRTFTEEISDYSRKLVGIVQHIEGGEQIVE 40 50 60 70 80 90 270 280 290 300 310 320 pF1KB4 DGIGMAHTEHVPGTAENARSCIRAYFYDLHETLCRQEEMALSVVDAHVREKLIWLRQQQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DGIGMAHTEHVPGTAENARSCIRAYFYDLHETLCRQEEMALSVVDAHVREKLIWLRQQQE 100 110 120 130 140 150 330 340 350 360 370 380 pF1KB4 DMTILLSEVSAACLHCEKTLQQDDCRVVLAKQEITRLLETLQKQQQQFTEVADHIQLDAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DMTILLSEVSAACLHCEKTLQQDDCRVVLAKQEITRLLETLQKQQQQFTEVADHIQLDAS 160 170 180 190 200 210 390 400 410 420 430 440 pF1KB4 IPVTFTKDNRVHIGPKMEIRVVTLGLDGAGKTTILFKLKQDEFMQPIPTIGFNVETVEYK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IPVTFTKDNRVHIGPKMEIRVVTLGLDGAGKTTILFKLKQDEFMQPIPTIGFNVETVEYK 220 230 240 250 260 270 450 460 470 480 490 500 pF1KB4 NLKFTIWDVGGKHKLRPLWKHYYLNTQAVVFVVDSSHRDRISEAHSELAKLLTEKELRDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NLKFTIWDVGGKHKLRPLWKHYYLNTQAVVFVVDSSHRDRISEAHSELAKLLTEKELRDA 280 290 300 310 320 330 510 520 530 540 550 560 pF1KB4 LLLIFANKQDVAGALSVEEITELLSLHKLCCGRSWYIQGCDARSGMGLYEGLDWLSRQLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LLLIFANKQDVAGALSVEEITELLSLHKLCCGRSWYIQGCDARSGMGLYEGLDWLSRQLV 340 350 360 370 380 390 570 pF1KB4 AAGVLDVA :::::::: XP_005 AAGVLDVA >>NP_001019399 (OMIM: 103180) ADP-ribosylation factor 1 (181 aa) initn: 698 init1: 558 opt: 699 Z-score: 424.9 bits: 86.9 E(85289): 6.3e-17 Smith-Waterman score: 699; 62.8% identity (86.0% similar) in 164 aa overlap (402-565:15-177) 380 390 400 410 420 430 pF1KB4 QQFTEVADHIQLDASIPVTFTKDNRVHIGPKMEIRVVTLGLDGAGKTTILFKLKQDEFMQ : :.:.. .:::.:::::::.::: :.. NP_001 MGNIFANLFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVT 10 20 30 40 440 450 460 470 480 490 pF1KB4 PIPTIGFNVETVEYKNLKFTIWDVGGKHKLRPLWKHYYLNTQAVVFVVDSSHRDRISEAH :::::::::::::::..::.:::::. :.::::.::. :::...:::::. :.:..::. NP_001 TIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAR 50 60 70 80 90 100 500 510 520 530 540 550 pF1KB4 SELAKLLTEKELRDALLLIFANKQDVAGALSVEEITELLSLHKLCCGRSWYIQGCDARSG :: ..:.: :::::.::.::::::. .:... :::. :.::.: :.::::. : :: NP_001 EELMRMLAEDELRDAVLLVFANKQDLPNAMNAAEITDKLGLHSLR-HRNWYIQATCATSG 110 120 130 140 150 160 560 570 pF1KB4 MGLYEGLDWLSRQLVAAGVLDVA :::::::::: :: NP_001 DGLYEGLDWLSNQLRNQK 170 180 >>NP_001019398 (OMIM: 103180) ADP-ribosylation factor 1 (181 aa) initn: 698 init1: 558 opt: 699 Z-score: 424.9 bits: 86.9 E(85289): 6.3e-17 Smith-Waterman score: 699; 62.8% identity (86.0% similar) in 164 aa overlap (402-565:15-177) 380 390 400 410 420 430 pF1KB4 QQFTEVADHIQLDASIPVTFTKDNRVHIGPKMEIRVVTLGLDGAGKTTILFKLKQDEFMQ : :.:.. .:::.:::::::.::: :.. NP_001 MGNIFANLFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVT 10 20 30 40 440 450 460 470 480 490 pF1KB4 PIPTIGFNVETVEYKNLKFTIWDVGGKHKLRPLWKHYYLNTQAVVFVVDSSHRDRISEAH :::::::::::::::..::.:::::. :.::::.::. :::...:::::. :.:..::. NP_001 TIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAR 50 60 70 80 90 100 500 510 520 530 540 550 pF1KB4 SELAKLLTEKELRDALLLIFANKQDVAGALSVEEITELLSLHKLCCGRSWYIQGCDARSG :: ..:.: :::::.::.::::::. .:... :::. :.::.: :.::::. : :: NP_001 EELMRMLAEDELRDAVLLVFANKQDLPNAMNAAEITDKLGLHSLR-HRNWYIQATCATSG 110 120 130 140 150 160 560 570 pF1KB4 MGLYEGLDWLSRQLVAAGVLDVA :::::::::: :: NP_001 DGLYEGLDWLSNQLRNQK 170 180 >>NP_001649 (OMIM: 103180) ADP-ribosylation factor 1 [Ho (181 aa) initn: 698 init1: 558 opt: 699 Z-score: 424.9 bits: 86.9 E(85289): 6.3e-17 Smith-Waterman score: 699; 62.8% identity (86.0% similar) in 164 aa overlap (402-565:15-177) 380 390 400 410 420 430 pF1KB4 QQFTEVADHIQLDASIPVTFTKDNRVHIGPKMEIRVVTLGLDGAGKTTILFKLKQDEFMQ : :.:.. .:::.:::::::.::: :.. NP_001 MGNIFANLFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVT 10 20 30 40 440 450 460 470 480 490 pF1KB4 PIPTIGFNVETVEYKNLKFTIWDVGGKHKLRPLWKHYYLNTQAVVFVVDSSHRDRISEAH :::::::::::::::..::.:::::. :.::::.::. :::...:::::. :.:..::. NP_001 TIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAR 50 60 70 80 90 100 500 510 520 530 540 550 pF1KB4 SELAKLLTEKELRDALLLIFANKQDVAGALSVEEITELLSLHKLCCGRSWYIQGCDARSG :: ..:.: :::::.::.::::::. .:... :::. :.::.: :.::::. : :: NP_001 EELMRMLAEDELRDAVLLVFANKQDLPNAMNAAEITDKLGLHSLR-HRNWYIQATCATSG 110 120 130 140 150 160 560 570 pF1KB4 MGLYEGLDWLSRQLVAAGVLDVA :::::::::: :: NP_001 DGLYEGLDWLSNQLRNQK 170 180 >>NP_001019397 (OMIM: 103180) ADP-ribosylation factor 1 (181 aa) initn: 698 init1: 558 opt: 699 Z-score: 424.9 bits: 86.9 E(85289): 6.3e-17 Smith-Waterman score: 699; 62.8% identity (86.0% similar) in 164 aa overlap (402-565:15-177) 380 390 400 410 420 430 pF1KB4 QQFTEVADHIQLDASIPVTFTKDNRVHIGPKMEIRVVTLGLDGAGKTTILFKLKQDEFMQ : :.:.. .:::.:::::::.::: :.. NP_001 MGNIFANLFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVT 10 20 30 40 440 450 460 470 480 490 pF1KB4 PIPTIGFNVETVEYKNLKFTIWDVGGKHKLRPLWKHYYLNTQAVVFVVDSSHRDRISEAH :::::::::::::::..::.:::::. :.::::.::. :::...:::::. :.:..::. NP_001 TIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAR 50 60 70 80 90 100 500 510 520 530 540 550 pF1KB4 SELAKLLTEKELRDALLLIFANKQDVAGALSVEEITELLSLHKLCCGRSWYIQGCDARSG :: ..:.: :::::.::.::::::. .:... :::. :.::.: :.::::. : :: NP_001 EELMRMLAEDELRDAVLLVFANKQDLPNAMNAAEITDKLGLHSLR-HRNWYIQATCATSG 110 120 130 140 150 160 560 570 pF1KB4 MGLYEGLDWLSRQLVAAGVLDVA :::::::::: :: NP_001 DGLYEGLDWLSNQLRNQK 170 180 >>NP_001650 (OMIM: 103190) ADP-ribosylation factor 3 [Ho (181 aa) initn: 694 init1: 558 opt: 697 Z-score: 423.8 bits: 86.7 E(85289): 7.3e-17 Smith-Waterman score: 697; 62.3% identity (85.6% similar) in 167 aa overlap (399-565:13-177) 370 380 390 400 410 420 pF1KB4 KQQQQFTEVADHIQLDASIPVTFTKDNRVHIGPKMEIRVVTLGLDGAGKTTILFKLKQDE :: : :.:.. .:::.:::::::.::: : NP_001 MGNIFGNLLKSLIGKK-EMRILMVGLDAAGKTTILYKLKLGE 10 20 30 40 430 440 450 460 470 480 pF1KB4 FMQPIPTIGFNVETVEYKNLKFTIWDVGGKHKLRPLWKHYYLNTQAVVFVVDSSHRDRIS .. :::::::::::::::..::.:::::. :.::::.::. :::...:::::. :.:.. NP_001 IVTTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVN 50 60 70 80 90 100 490 500 510 520 530 540 pF1KB4 EAHSELAKLLTEKELRDALLLIFANKQDVAGALSVEEITELLSLHKLCCGRSWYIQGCDA ::. :: ..:.: :::::.::.::::::. .:... :::. :.::.: :.::::. : NP_001 EAREELMRMLAEDELRDAVLLVFANKQDLPNAMNAAEITDKLGLHSLR-HRNWYIQATCA 110 120 130 140 150 160 550 560 570 pF1KB4 RSGMGLYEGLDWLSRQLVAAGVLDVA :: :::::::::. :: NP_001 TSGDGLYEGLDWLANQLKNKK 170 180 574 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 15:25:36 2016 done: Thu Nov 3 15:25:37 2016 Total Scan time: 8.300 Total Display time: 0.050 Function used was FASTA [36.3.4 Apr, 2011]