FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB4708, 444 aa 1>>>pF1KB4708 444 - 444 aa - 444 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.2639+/-0.000993; mu= 17.2422+/- 0.059 mean_var=57.5379+/-12.074, 0's: 0 Z-trim(103.2): 21 B-trim: 394 in 1/49 Lambda= 0.169082 statistics sampled from 7280 (7295) to 7280 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.6), E-opt: 0.2 (0.224), width: 16 Scan time: 2.710 The best scores are: opt bits E(32554) CCDS8012.1 FADS2 gene_id:9415|Hs108|chr11 ( 444) 3118 769.1 0 CCDS60807.1 FADS2 gene_id:9415|Hs108|chr11 ( 422) 2641 652.8 1.9e-187 CCDS60808.1 FADS2 gene_id:9415|Hs108|chr11 ( 413) 2637 651.8 3.7e-187 CCDS8013.1 FADS3 gene_id:3995|Hs108|chr11 ( 445) 2051 508.9 4.2e-144 CCDS8011.2 FADS1 gene_id:3992|Hs108|chr11 ( 501) 1984 492.5 3.9e-139 >>CCDS8012.1 FADS2 gene_id:9415|Hs108|chr11 (444 aa) initn: 3118 init1: 3118 opt: 3118 Z-score: 4107.2 bits: 769.1 E(32554): 0 Smith-Waterman score: 3118; 100.0% identity (100.0% similar) in 444 aa overlap (1-444:1-444) 10 20 30 40 50 60 pF1KB4 MGKGGNQGEGAAEREVSVPTFSWEEIQKHNLRTDRWLVIDRKVYNITKWSIQHPGGQRVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS80 MGKGGNQGEGAAEREVSVPTFSWEEIQKHNLRTDRWLVIDRKVYNITKWSIQHPGGQRVI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 GHYAGEDATDAFRAFHPDLEFVGKFLKPLLIGELAPEEPSQDHGKNSKITEDFRALRKTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS80 GHYAGEDATDAFRAFHPDLEFVGKFLKPLLIGELAPEEPSQDHGKNSKITEDFRALRKTA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 EDMNLFKTNHVFFLLLLAHIIALESIAWFTVFYFGNGWIPTLITAFVLATSQAQAGWLQH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS80 EDMNLFKTNHVFFLLLLAHIIALESIAWFTVFYFGNGWIPTLITAFVLATSQAQAGWLQH 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 DYGHLSVYRKPKWNHLVHKFVIGHLKGASANWWNHRHFQHHAKPNIFHKDPDVNMLHVFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS80 DYGHLSVYRKPKWNHLVHKFVIGHLKGASANWWNHRHFQHHAKPNIFHKDPDVNMLHVFV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 LGEWQPIEYGKKKLKYLPYNHQHEYFFLIGPPLLIPMYFQYQIIMTMIVHKNWVDLAWAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS80 LGEWQPIEYGKKKLKYLPYNHQHEYFFLIGPPLLIPMYFQYQIIMTMIVHKNWVDLAWAV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 SYYIRFFITYIPFYGILGALLFLNFIRFLESHWFVWVTQMNHIVMEIDQEAYRDWFSSQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS80 SYYIRFFITYIPFYGILGALLFLNFIRFLESHWFVWVTQMNHIVMEIDQEAYRDWFSSQL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB4 TATCNVEQSFFNDWFSGHLNFQIEHHLFPTMPRHNLHKIAPLVKSLCAKHGIEYQEKPLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS80 TATCNVEQSFFNDWFSGHLNFQIEHHLFPTMPRHNLHKIAPLVKSLCAKHGIEYQEKPLL 370 380 390 400 410 420 430 440 pF1KB4 RALLDIIRSLKKSGKLWLDAYLHK :::::::::::::::::::::::: CCDS80 RALLDIIRSLKKSGKLWLDAYLHK 430 440 >>CCDS60807.1 FADS2 gene_id:9415|Hs108|chr11 (422 aa) initn: 2637 init1: 2637 opt: 2641 Z-score: 3478.7 bits: 652.8 E(32554): 1.9e-187 Smith-Waterman score: 2641; 96.7% identity (98.0% similar) in 393 aa overlap (53-444:35-422) 30 40 50 60 70 80 pF1KB4 WEEIQKHNLRTDRWLVIDRKVYNITKWSIQHPGGQRVIGH-YAGEDATDAFRAFHPDLEF ::.. :: .:.. :::::::::::: CCDS60 EAGPFVCVCVLLASIPTPQTPLLQASLPPFHPASA---GHPITGQQ--DAFRAFHPDLEF 10 20 30 40 50 90 100 110 120 130 140 pF1KB4 VGKFLKPLLIGELAPEEPSQDHGKNSKITEDFRALRKTAEDMNLFKTNHVFFLLLLAHII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 VGKFLKPLLIGELAPEEPSQDHGKNSKITEDFRALRKTAEDMNLFKTNHVFFLLLLAHII 60 70 80 90 100 110 150 160 170 180 190 200 pF1KB4 ALESIAWFTVFYFGNGWIPTLITAFVLATSQAQAGWLQHDYGHLSVYRKPKWNHLVHKFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 ALESIAWFTVFYFGNGWIPTLITAFVLATSQAQAGWLQHDYGHLSVYRKPKWNHLVHKFV 120 130 140 150 160 170 210 220 230 240 250 260 pF1KB4 IGHLKGASANWWNHRHFQHHAKPNIFHKDPDVNMLHVFVLGEWQPIEYGKKKLKYLPYNH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 IGHLKGASANWWNHRHFQHHAKPNIFHKDPDVNMLHVFVLGEWQPIEYGKKKLKYLPYNH 180 190 200 210 220 230 270 280 290 300 310 320 pF1KB4 QHEYFFLIGPPLLIPMYFQYQIIMTMIVHKNWVDLAWAVSYYIRFFITYIPFYGILGALL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 QHEYFFLIGPPLLIPMYFQYQIIMTMIVHKNWVDLAWAVSYYIRFFITYIPFYGILGALL 240 250 260 270 280 290 330 340 350 360 370 380 pF1KB4 FLNFIRFLESHWFVWVTQMNHIVMEIDQEAYRDWFSSQLTATCNVEQSFFNDWFSGHLNF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 FLNFIRFLESHWFVWVTQMNHIVMEIDQEAYRDWFSSQLTATCNVEQSFFNDWFSGHLNF 300 310 320 330 340 350 390 400 410 420 430 440 pF1KB4 QIEHHLFPTMPRHNLHKIAPLVKSLCAKHGIEYQEKPLLRALLDIIRSLKKSGKLWLDAY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 QIEHHLFPTMPRHNLHKIAPLVKSLCAKHGIEYQEKPLLRALLDIIRSLKKSGKLWLDAY 360 370 380 390 400 410 pF1KB4 LHK ::: CCDS60 LHK 420 >>CCDS60808.1 FADS2 gene_id:9415|Hs108|chr11 (413 aa) initn: 2637 init1: 2637 opt: 2637 Z-score: 3473.6 bits: 651.8 E(32554): 3.7e-187 Smith-Waterman score: 2637; 100.0% identity (100.0% similar) in 375 aa overlap (70-444:39-413) 40 50 60 70 80 90 pF1KB4 DRKVYNITKWSIQHPGGQRVIGHYAGEDATDAFRAFHPDLEFVGKFLKPLLIGELAPEEP :::::::::::::::::::::::::::::: CCDS60 RRVNSLMLYTLRSITSHRSSHPERWATSSQDAFRAFHPDLEFVGKFLKPLLIGELAPEEP 10 20 30 40 50 60 100 110 120 130 140 150 pF1KB4 SQDHGKNSKITEDFRALRKTAEDMNLFKTNHVFFLLLLAHIIALESIAWFTVFYFGNGWI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 SQDHGKNSKITEDFRALRKTAEDMNLFKTNHVFFLLLLAHIIALESIAWFTVFYFGNGWI 70 80 90 100 110 120 160 170 180 190 200 210 pF1KB4 PTLITAFVLATSQAQAGWLQHDYGHLSVYRKPKWNHLVHKFVIGHLKGASANWWNHRHFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 PTLITAFVLATSQAQAGWLQHDYGHLSVYRKPKWNHLVHKFVIGHLKGASANWWNHRHFQ 130 140 150 160 170 180 220 230 240 250 260 270 pF1KB4 HHAKPNIFHKDPDVNMLHVFVLGEWQPIEYGKKKLKYLPYNHQHEYFFLIGPPLLIPMYF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 HHAKPNIFHKDPDVNMLHVFVLGEWQPIEYGKKKLKYLPYNHQHEYFFLIGPPLLIPMYF 190 200 210 220 230 240 280 290 300 310 320 330 pF1KB4 QYQIIMTMIVHKNWVDLAWAVSYYIRFFITYIPFYGILGALLFLNFIRFLESHWFVWVTQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 QYQIIMTMIVHKNWVDLAWAVSYYIRFFITYIPFYGILGALLFLNFIRFLESHWFVWVTQ 250 260 270 280 290 300 340 350 360 370 380 390 pF1KB4 MNHIVMEIDQEAYRDWFSSQLTATCNVEQSFFNDWFSGHLNFQIEHHLFPTMPRHNLHKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS60 MNHIVMEIDQEAYRDWFSSQLTATCNVEQSFFNDWFSGHLNFQIEHHLFPTMPRHNLHKI 310 320 330 340 350 360 400 410 420 430 440 pF1KB4 APLVKSLCAKHGIEYQEKPLLRALLDIIRSLKKSGKLWLDAYLHK ::::::::::::::::::::::::::::::::::::::::::::: CCDS60 APLVKSLCAKHGIEYQEKPLLRALLDIIRSLKKSGKLWLDAYLHK 370 380 390 400 410 >>CCDS8013.1 FADS3 gene_id:3995|Hs108|chr11 (445 aa) initn: 2076 init1: 1064 opt: 2051 Z-score: 2700.5 bits: 508.9 E(32554): 4.2e-144 Smith-Waterman score: 2051; 62.6% identity (84.1% similar) in 446 aa overlap (1-444:1-445) 10 20 30 40 50 pF1KB4 MGKGGNQG--EGAAEREVSVPTFSWEEIQKHNLRTDRWLVIDRKVYNITKWSIQHPGGQR :: :. : :: :. . .::: ::.:. :. :.::::.:.::.:..:. .::::.: CCDS80 MGGVGEPGPREGPAQPGAPLPTFCWEQIRAHDQPGDKWLVIERRVYDISRWAQRHPGGSR 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB4 VIGHYAGEDATDAFRAFHPDLEFVGKFLKPLLIGELAPEEPSQDHGKNSKITEDFRALRK .:::...::::::::::: ::.:: :::.::::::::::::::: :....::::::.. CCDS80 LIGHHGAEDATDAFRAFHQDLNFVRKFLQPLLIGELAPEEPSQDGPLNAQLVEDFRALHQ 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB4 TAEDMNLFKTNHVFFLLLLAHIIALESIAWFTVFYFGNGWIPTLITAFVLATSQAQAGWL .::::.:: .. .:: .::.::.:.: .::. .. .: ::.:. ..::.:: ::::. : CCDS80 AAEDMKLFDASPTFFAFLLGHILAMEVLAWLLIYLLGPGWVPSALAAFILAISQAQSWCL 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB4 QHDYGHLSVYRKPKWNHLVHKFVIGHLKGASANWWNHRHFQHHAKPNIFHKDPDVNMLHV ::: :: :...: :::...:::.:.::: ::.::: ::::::::::::::::::.. : CCDS80 QHDLGHASIFKKSWWNHVAQKFVMGQLKGFSAHWWNFRHFQHHAKPNIFHKDPDVTVAPV 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB4 FVLGEWQPIEYGKKKLKYLPYNHQHEYFFLIGPPLLIPMYFQYQIIMTMIVHKNWVDLAW :.::: . .:::::: .:::::.:: :::::::::: . :. . . :.: .:.:: : CCDS80 FLLGE-SSVEYGKKKRRYLPYNQQHLYFFLIGPPLLTLVNFEVENLAYMLVCMQWADLLW 250 260 270 280 290 300 310 320 330 340 350 pF1KB4 AVSYYIRFFITYIPFYGILGALLFLNFIRFLESHWFVWVTQMNHIVMEIDQEAYRDWFSS :.:.: :::..:.::::. :.:::. .: ::::::::.:::::: :: .: .::: :: CCDS80 AASFYARFFLSYLPFYGVPGVLLFFVAVRVLESHWFVWITQMNHIPKEIGHEKHRDWVSS 300 310 320 330 340 350 360 370 380 390 400 410 pF1KB4 QLTATCNVEQSFFNDWFSGHLNFQIEHHLFPTMPRHNLHKIAPLVKSLCAKHGIEYQEKP ::.:::::: :.:..:::::::::::::::: ::::: ..::::::::::::. :. :: CCDS80 QLAATCNVEPSLFTNWFSGHLNFQIEHHLFPRMPRHNYSRVAPLVKSLCAKHGLSYEVKP 360 370 380 390 400 410 420 430 440 pF1KB4 LLRALLDIIRSLKKSGKLWLDAYLHK .: ::.::.::::::: .:::::::. CCDS80 FLTALVDIVRSLKKSGDIWLDAYLHQ 420 430 440 >>CCDS8011.2 FADS1 gene_id:3992|Hs108|chr11 (501 aa) initn: 2028 init1: 1030 opt: 1984 Z-score: 2611.4 bits: 492.5 E(32554): 3.9e-139 Smith-Waterman score: 1984; 63.4% identity (84.1% similar) in 440 aa overlap (11-444:64-501) 10 20 30 pF1KB4 MGKGGNQGEGAAEREVSVPT---FSWEEIQKHNLRTDRWL ::: .. :: :.:.:. ... .::: CCDS80 WSPRTPSTRLTAPAGPARGVARPAMAPDPVAAETAAQGPTPRYFTWDEVAQRSGCEERWL 40 50 60 70 80 90 40 50 60 70 80 90 pF1KB4 VIDRKVYNITKWSIQHPGGQRVIGHYAGEDATDAFRAFHPDLEFVGKFLKPLLIGELAPE :::::::::.... .::::.:::.::::.:::: : ::: . .: :... ::::::.:: CCDS80 VIDRKVYNISEFTRRHPGGSRVISHYAGQDATDPFVAFHINKGLVKKYMNSLLIGELSPE 100 110 120 130 140 150 100 110 120 130 140 150 pF1KB4 EPSQDHGKNSKITEDFRALRKTAEDMNLFKTNHVFFLLLLAHIIALESIAWFTVFYFGNG .:: . ::...:..:: :: :.: :.:.:.::::::: : ::. :.. ::.:.. ::.. CCDS80 QPSFEPTKNKELTDEFRELRATVERMGLMKANHVFFLLYLLHILLLDGAAWLTLWVFGTS 160 170 180 190 200 210 160 170 180 190 200 210 pF1KB4 WIPTLITAFVLATSQAQAGWLQHDYGHLSVYRKPKWNHLVHKFVIGHLKGASANWWNHRH ..: :. : .:.. ::::::::::.:::::. :::::.:.::::::::: :.:::: : CCDS80 FLPFLLCAVLLSAVQAQAGWLQHDFGHLSVFSTSKWNHLLHHFVIGHLKGAPASWWNHMH 220 230 240 250 260 270 220 230 240 250 260 270 pF1KB4 FQHHAKPNIFHKDPDVNMLH--VFVLGEWQPIEYGKKKLKYLPYNHQHEYFFLIGPPLLI :::::::: :.::::.:: : :.::. .: ::.: ::.::::::.:::::::: :. CCDS80 FQHHAKPNCFRKDPDINM-HPFFFALGKILSVELGKQKKKYMPYNHQHKYFFLIGPPALL 280 290 300 310 320 330 280 290 300 310 320 330 pF1KB4 PMYFQYQIIMTMIVHKNWVDLAWAVSYYIRFFITYIPFYGILGALLFLNFI-RFLESHWF :.:::. :.. .: .:.:::::: ...:.:::.::.:. : : :.: : :: :::::.:: CCDS80 PLYFQWYIFYFVIQRKKWVDLAWMITFYVRFFLTYVPLLG-LKAFLGLFFIVRFLESNWF 340 350 360 370 380 390 340 350 360 370 380 390 pF1KB4 VWVTQMNHIVMEIDQEAYRDWFSSQLTATCNVEQSFFNDWFSGHLNFQIEHHLFPTMPRH ::::::::: :.::.. :: :.:: :::::..: :::::::::::::::::::::::: CCDS80 VWVTQMNHIPMHIDHDRNMDWVSTQLQATCNVHKSAFNDWFSGHLNFQIEHHLFPTMPRH 400 410 420 430 440 450 400 410 420 430 440 pF1KB4 NLHKIAPLVKSLCAKHGIEYQEKPLLRALLDIIRSLKKSGKLWLDAYLHK : ::.::::.::::::::::: :::: :. :::.:::.::.::::::::. CCDS80 NYHKVAPLVQSLCAKHGIEYQSKPLLSAFADIIHSLKESGQLWLDAYLHQ 460 470 480 490 500 444 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 06:01:40 2016 done: Sat Nov 5 06:01:41 2016 Total Scan time: 2.710 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]